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alostwanderernotfound · 2 months ago

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HIV and COVID

A major barrier to preventing the spread of HIV is accurate test results.

There is a high chance there are many people with HIV that have it and do not know. We do not know how long this undetected time period is (lentiviruses are often associated with long periods of time of virus activity that goes undetected- 5 to 10 years or more), but there is a chance many individuals with HIV go undiagnosed for many years. Individuals during this time before an HIV diagnosis complain of fatigue and many undiagnosed disabling symptoms during that time period. HIV is able to cause changes to immune cells that prevent HIV tests from finding the infection. Some people get negative HIV tests when they are HIV positive. This means you could be HIV negative, but still have HIV in your blood and can spread HIV to other individuals.

Getting a COVID vaccination (and sometimes other vaccinations like the flu vaccination) can help the body identify HIV hiding in the body. This allows earlier treatment and intervention. Once HIV has been identified, it also reduces the risk for all individuals in our population to be exposed to more severe infections.

Getting tested regularly for HIV used to be part of our federal public health recommendations.

This just further emphasizes why this information is so important to know and healthcare needs to start testing for more diseases in more people and do these tests more often.

People often assume their infection came from an unfaithful partner, but in reality HIV has been spreading unknowingly to many in the medical community and still in the public sphere no one is talking about it like the huge deal it is.

This potential means people could be raped as a child, never have sex again, never encounter drugs, and then be miserable & living with an active HIV infection into their early 20s and they would never know. Once they got a positive test result they would have no idea where the infection even came from.

Our entire understanding of these types of diseases has to change and the seriousness of this topic has to be addressed by the world. This was theorized as a mechanism of HIV spread due to how many people were getting diagnosed but had no identifiable cause of their HIV, but now it’s proven and right in front of us. This is disastrous.

To everyone that told the truth about how they didn’t know how they got these types of diseases & how they had no idea where they got it from then faced judgement from others and even the medical community- you aren’t crazy.

On behalf of everything these types of diseases did to destroy families, relationships, and your body, I’m going to apologize right now for all the individuals that I know won’t ever give you an apology for what they did and what they said.

I believe you. I always did.

Without you telling your truth , we never would have been able to figure this out about HIV.

HIV is spreading in “HIV negative” individuals to other individuals as some researchers theorized.

The mRNA vaccination technology developed is now the foundation for the next generation of HIV treatment and disease control. We must continue to push and advocate for improving the lives of all people with disease and we all just took a huge step forward.

You do not have to be sexually active to develop HIV. Your sexual trauma doesn’t have to define your life for the rest of your life- you are stronger than you know and braver than you feel.

Find a place to get tested for HIV here:

I still recommend getting a NAT or “viral load” test done as the first test to see if you have HIV.

I think considering what we know about HIV and in consideration of all the things we still don’t know that this is the safest option. Any other test for this condition available today has too high of a chance of producing a wrong result. I find it extremely uncomfortable we still use the other types of tests in the hospital and doctor office settings.

If you choose to order a test through an online service be aware some tests only tell you about either HIV-1 or HIV-2 and will not always provide you information related to type 1 and type 2.

For example, here:

This will provide you information related to ordering a test that looks for both types of HIV instead of just one strain of HIV.

Stay safe.

#hiv #virus #sick #chronically ill #chronic pain #chronic illness #chronic fatigue #pain #doctor #medicine #viral

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batmanisagatewaydrug · 5 months ago

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would you like to tell us about your research on virginity?

but also...wdym STIs aren't as scary as we think??? I was told most of them are incurable? I know you can make aids untrasmittable and that they've even succeded in curing it a couple times but that's about it. I would love to be educated about this

yeah, the basic idea with the virginity project was that the whole concept of virginity is pretty bullshit in the context in which it was initially significant, namely cisgender women being penetrated by cisgender men, so as soon as you take it outside of that context by introducing gay and trans sexuality it totally falls apart. I mean, hell, it stops working if you even look at two cishet people doing literally anything OTHER than penis-in-vagina sex. I tripped up so many people initially when I started asking questions like "okay, so you don't think a woman loses her virginity from a man going down on her. so what if it's two women? what's the difference?" and just really getting people to face down their very penis-centered view of the sex, to the result of several people telling me that it kind of made them reevaluate what they actually think of as the first time they had sex. it's also fascinating to either read other people's accounts or discuss firsthand how queer people have either tried to make themselves fit into the binary of virginity - queer man disagreeing over whether or not you have to have penetrative anal sex to lose your virginity or oral sex is sufficient, a fascinating case of a lesbian who felt that have sex with other cis women didn't "count" and asked a cis male friend to have sex with her just so she could feel satisfied that she'd lost her virginity - or abandon it entirely. Hanne Blank's book Virgin was a formative starting point, and it really exploded for me from there.

as for the STIs - hey, bad news! you fell victim to the scare tactics used to make people afraid of sex! almost all sexually transmitted infections are very easy to treat and cure with the right medicine, which is why it's important to get tested regularly and check in with your healthcare provider at the first sign of something amiss. pubic lice, scabies, trichomoniasis, gonorrhea, chlamydia, syphilis - all of those are pretty easy to get rid of with some help from your doctor and a run to the pharmacy!

the major exceptions are the 4 H's: herpes, HIV, HPV, and hepatitis B.

herpes is with you forever but is an incredibly mild companion to share your body with, considering most people never experience any notable symptoms and those who do can curb the severity with medicine.

it's also worth noting that herpes is so common as to be virtually ubiquitous; the World Health Organization consistently estimates that somewhere around 80% of the world's adult population is carrying herpes simplex virus 1 or herpes simplex virus 2. a great deal of those people don't even get it from having sex, but rather by catching HSV-1 from a parent or other people they come is close contact with as a child.

you're actually thinking of HIV (human immunodeficiency virus) when you mention AIDS becoming untransmittable, but that's still a very good thing! the care available for people with HIV has come incredibly far since AIDS first became known and claimed so many lives, and today it's more than possible for people infected with HIV to live long, healthy lives by taking the proper medication to manage their viral load.

with management, people with HIV will not develop AIDS (which happens when the immune system is sufficiently depleted by HIV) and by consistently taking their medication people with HIV can become undetectable (the viral load in their body is too small to be detected or measured in tests), at which point they are unable to transmit the virus to other people.

HPV (human paillomavirus) comes in many different strains, most of which are absolutely harmless and go away on their own after a couple of months or years of freeloading in your body. I cannot emphasize this enough: HPV is so common that virtually everyone who has sex has, will have, or has had it in their lives, and the vast, VAST majority of those people will never be troubled by it literally at all.

the trouble comes from a few strains of HPV that can cause genital warts, and a few others that can cause cancers in the throat, anus, cervix, vulva, vagina, and penis. while HPV can't be treated, you can reduce your risk of developing cancer by getting the HPV vaccine if you haven't already and, if you have a cervix, getting regular Pap smears to catch early warning signs of cancerous developments.

hepatitis B is a viral infection that targets the liver. in rare cases it can cause chronic health problems that can be very dangerous, but I have to emphasize that's not common. in most adults who get hep B, there will be no symptoms and it will resolve itself in a matter of weeks. the infection is riskiest in children, but at least in America most people have received vaccines against hepatitis B as babies since the 90s.

in conclusion: get your shots, take your medicine, use protection, get tested, and talk to your doctor, but know that if there's one thing humans are good at it's figuring out how to manage STIs. we've been doing it for a long time - most sexually transmitted infections and parasites have been with us since before we we became modern humans - so we're really good at it!

#sex edventures 2024 #sti posts

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lastoneout · 8 months ago

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Things that can go in/pass through the vagina just fine:

penis (and/or semen)

sex toys made of body-safe materials

condoms (male and female)

lube

infants you are actively giving birth to

all that other shit that comes outta there during childbirth

period blood

mucus your body naturally produces so long as it doesn't smell or look weird

tongue

fingers

tampons and menstrual cups

IUD or other insertable birth control methods

ovulation tests

medical devices used during pap smears and pelvic exams or IVF treatments

dilators for those who've had bottom surgery

medications as directed by your doctor(like estrogen cream to prevent vaginal atrophy when on testosterone)

Things that should not go in there!!!

soap, oh my god do not put soap in there holy shit

food

flavored condoms/lube

douching fluids

crystals/special rocks

blood that isn't yours

pregnancy tests(you're supposed to pee on them)

sex toys made out of non-body safe materials unless you put a condom on them

stuff that isn't sterile or hasn't been cleaned properly

no fr like if you are doing anal you NEED to clean your penis/sex toy or at least swap to a new condom before putting it in the vagina holy fucking infections batman

anything you're allergic to(this includes everything on the safe list, if you're allergic to it it's not safe)

the body parts/bodily fluids of someone who has an STI unless you guys have protection(condoms, dental dams, latex gloves, you're taking PrEP/medications to keep your HIV viral load low enough that you can't pass it on, ect.)

Not a comprehensive list ofc but like since it does seem we occasionally need the reminder here ya go. If you're unsure about anything planned parenthood has a lot of sex education material up on their website, def check it out!!

#nsft

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covid-safer-hotties · 3 months ago

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Yes, there's hope in the fight against Long Covid.

Hope doesn't come in the form of natural immunity or subpar vaccines rolled out after waves of illness have already peaked. It comes in the form of clean indoor air, widespread masking, and better treatments. In that vein, the NIH is finally launching a new batch of clinical trials focused on Long Covid, five total, dedicated to different aspects of the condition. Institutes like Mount Sinai are running clinical trials on repurposed HIV drugs. So is HealthBio, a startup working on immune diseases. (They're testing maraviroc and atorvastatin.) Post-Viral Trials News is sharing updates as they roll in. Of course, the NIH and FDA need steady pressure to make sure they're funding trials that focus on a range of options. Given the urgency of the crisis, we should be doing far more. As Harvard economist David Cutler has said on developing treatments for Long Covid, "There is no amount that's overdoing it." We're talking about a $16 trillion crisis.

We're talking about an urgent need for dozens of expedited clinical trials for drugs that already exist, which have shown effectiveness in preventing and treating Long Covid in its various incarnations. We're talking about making those drugs accessible right now for off-label use, so that Covid survivors can finally get the help they need.

Long Covid is an emergency.

We're going to talk about prescription treatments first, and then supplements and extracts you can find yourself. Up front, you can try services like RTHM and CURE ID that aim to connect patients with treatments without endless waits. (I'm not endorsing them. I'm just telling you they exist.)

Let's dig in.

Healthcare largely abandoned monoclonal antibodies during the first Omicron wave, but some of them remain effective in higher doses as postviral therapies. We've also found new ones. For example: A study in Nature offers 5B8 as a therapy for fibrinogen, a protein in your body that binds to the Covid spike protein during infection. Afterward, that protein starts to behave differently, "forming pro-inflammatory blood clots" that lead to cardiac and brain dysfunction, especially in young patients with mild infections. It also suppresses your natural killer cells, weakening your immune system. So, damaged fibrinogen is the culprit behind a lot of the "mysterious" health problems we're seeing.

As the authors show, "fibrin-targeting immunotherapy may represent a therapeutic intervention for patients with acute Covid-19 and Long Covid." The monoclonal antibody 5B8 "provides protection...without adverse effects." The sooner you get it, the better it works.

A 2024 study in the American Journal of Emergency Medicine also found that the monoclonal antibody regeneron helped Long Covid survivors recover. Researchers "expressed surprise at the swift and comprehensive improvements observed in the patients," adding that "regardless of the duration of their Long Covid experience, significant progress was noted within a mere 5 days of receiving the Regeneron treatment." It might work because it helps your immune system eliminate residual amounts of virus or viral fragments, or it might replace damaged antibodies that attack your cells.

A 2022 study found that another monoclonal antibody, Sotrovimab, helped survivors with persistent viral loads after initial infection who were still reporting fatigue, chest pain, and trouble breathing months after infection. As the researchers note, the patients showed "rapid improvement of symptoms and inflammation markers as well as negative swabs."

Yet another 2022 study in Clinical Infectious Diseases found that a monoclonal antibody treatment called Leronlimab could help Long Covid patients recover by boosting their immune system in cases where Covid downregulated it, causing a drop in their CCR5 levels, a receptor found on a range of cells that fight pathogens, including your CD4 lymphocytes.

The Long Covid Action Project is also developing a list of drugs that desperately need clinical trials and faster deployment. They stress the need for monoclonal antibodies and antivirals like pemivibart, azvudine, ensitrelvir (Xocova), and sofosbuvir. They'll be releasing a full list later this year.

So while these monoclonal antibodies might not save your life during early infection, they can help your recovery.

There should be more clinical trials and off-label use.

Interferon treatments, specifically Interferon-Lambda, have shown the potential to help with immune system problems and cognitive deficits (caused by brain inflammation) after Covid infections.

Also:

A 2022 study in Frontiers in Immunology found that high doses of immunoglobulin have shown "a significant to remarkable clinical benefit" in treating a full range of brain, heart, and lung problems in Long Covid patients. A major 2023 study in Frontiers in Neuroscience confirmed that immunoglobulin lead to significant improvement in neurological problems. As researchers in a third study on immunoglobulins and Long Covid state, we already use this therapy to treat a variety of chronic inflammatory diseases, as well as flu, HIV, and measles. (The NIH has included immunoglobulins in their new clinical trials.)

HIV drugs have also shown promise for helping Long Covid patients. A 2023 study in Clinical Infectious Diseases found that Tenofovir reduced someone's Covid risk regardless of whether they had HIV. A range of studies have supported the use of Tenofovir, Darunavir Ethanolate, and Azvudine for Covid. As we noted earlier, clinical trials are currently testing HIV drugs for Long Covid.

Another study in Antiviral Research found that cobicistat, used to boost HIV antivirals, also fights Covid and leads to a significant reduction in overall risk. The researchers found that higher doses work better. They also found that higher doses work better for ritonavir, one of the key components of Paxlovid. By the way, ritonavir has been used in HIV treatments since the mid-1990s.

The research on repurposed HIV drugs points to the potential of many antiretroviral therapy (ART) medications for Long Covid, given that viral persistence plays a large role in most cases.

When you consider that Paxlovid itself contains an HIV antiviral, it sounds a little less extreme to compare Covid to HIV and discuss repurposing existing drugs.

Finally, studies have shown that molnupiravir and metformin have shown effectiveness against Covid. In particular, a 2024 study in Clinical Infectious Diseases found that metformin prescribed in the early stages of a Covid infection led to a 41 percent drop in Long Covid risk.

Other research has revealed that sometimes it takes a combination of these drugs to help patients recover. In a 2022 study in Clinical Infectious Diseases, researchers used nanopore technology to identify the specific variants patients were infected with and select the most effective treatments for that variant. In one case, a Long Covid patient with severe Paxlovid rebound only got better after doctors prescribed Paxlovid again and added remdesivir. Nobody had thought to try that yet.

It worked.

These are the drugs that demand renewed attention and clinical trials, given that most research on Long Covid points to ongoing infection, viral persistence, and the disruption of your immune system, which could mean a downregulated or weakened immune system or an overactive one. We especially need clinical trials that match drugs with specific conditions.

Specialists are going to decide the right dose for prescription drugs. Generally, the research indicates that if a standard dose doesn't work, a higher dose might as long as it doesn't trigger side effects. A combination of drugs can work when a single drug fails.

What can you do if you don't have access to these drugs?

This:

A major 2023 study in Cells found that eriodictyol, a flavonoid extracted from yerba santa, can help with the brain inflammation caused by Covid infections that leads to cognitive deficits and fatigue. Researchers have found that at least part of the "brain fog" from Long Covid happens when the virus triggers immune cells to attack the brain. Eriodictyol can also be derived from citrus fruits, tomatoes, and grapes. As the authors explain, a range of flavonoids "have been reported to prevent neuroinflammation, provide neuroprotection, and reduce cognitive dysfunction, especially brain fog."

The authors of the Cell study list flavanoids liposomal luteolin, oleuropein, and sulforaphane as all beneficial for recovering brain function. They identify formulas called BrainGain and FibroProtek containing flavonoids that helped Long Covid patients with severe brain fog in previous studies. Those contain luteolin. They ultimately recommend ViralProtek, which combines several flavonoids, "alone or together" with eriodictyol.

These formulas aren't just managing symptoms. According to the studies, they're helping you clear viral remnants and rehabilitate your immune system. They inhibit your microglia and mast cells, immune cells that often drive the brain inflammation behind Long Covid cognitive problems.

What else?

A 2022 study in Molecules found promise in nattokinase, "a popular traditional Japanese food made from soybeans fermented by Bacillus subtilis var." Not so coincidentally, nattokinase also "decreases the plasma levels of fibrinogen," the same protein that drives thrombosis in Long Covid patients and indeed "has drawn central attention in thrombolytic drug studies," as well as tumor treatment. It also inhibits the replication of bovine herpes virus. Clinical trials have found no adverse effects from eating natto. In this particular study, the researchers found that nattokinase degrades the Covid spike protein, inhibiting infection. As they conclude, "nattokinase and natto extracts have potential effects on the inhibition of SAS-cOv-2 host cell entry."

Martha Eckey describes natto extracts in more detail here, along with benefits, recommended dosage, and possible side effects. Respondents to her survey reported the best results when they took Solaray's natto extract along with serrapeptase, an enzyme and commonly used drug in Japan and Europe that helps your body break down proteins. A large number of patients reported improvement after taking the natto-serra combination, often within a week or two. Many of them also benefited from adding lumbrokinase, an enzyme shown to facilitate healing.

Like natto, lumbrokinase breaks down fibrin. We're seeing a theme here. Any kind of treatment that breaks down fibrin, whether it's a monoclonal antibody or an enzyme, helps after a Covid infection.

Take a look for yourself:

Eckey discusses cromolyn for brain inflammation and neurological issues, and some people have said it helps with other problems. She also wrote this great post about protecting kids from Long Covid.

A lot of it also applies to adults.

Another surprising study in Viruses from 2021 found that grapeseed extract (V. vinifera) contained dozens of flavonoid compounds that inhibited viral replication, including for Covid. The researchers used concentrations from 500 μg/ml down to 10 μg/ml.

Studies have even found that taurine supplements can do a lot to reduce your Covid risks, including Long Covid. A 2024 study in PLoS One found that the amino acid can serve as both a biomarker and a target for treatment in Long Covid. As they write, taurine has already "shown benefits such as reducing depressive behavior, improving memory, and mitigating age-related issues by addressing cellular senescence, chronic inflammation, DNA damage, and mitochondrial dysfunction." It can play "a potential protective role" in "alleviating the burdens of PCC." If that weren't enough, "taurine supplementation has demonstrated diverse therapeutic properties, including anti-oxidation, anti-aging, antiepileptic, cytoprotective, and cardioprotective effects in many diseases." Yes, even taurine from energy drinks. (And I guess it's a good thing I drink them.)

A standard diet contains about 40-400 mg of taurine per day. Medical use often starts at 6 grams a day.

There's a reason why many of these treatments don't get the attention they deserve, and Timothy Ferriss of all people describes it very well in the opening to The 4-Hour Body. As he learns from talking with a wide range of doctors and medical researchers, the industry frowns on any kind of treatment that doesn't look or feel "elite" enough. There's not a lot of incentive for major research on supplements or cheap, widely available drugs because they're just not cool enough, even if they work. For drug makers, it can't just work. It also has to generate enough profit.

That's what happens when you privatize medicine.

As a society, we have to overcome that. This shortcoming isn't going to help us address the myriad public health challenges of the future.

It's a little ironic that the catchphrase "do your own research," once levied against anti-vaxxers, is now used to insult Long Covid survivors and advocates who are trying desperately to find treatments. The difference is that we're not rejecting medicines.

We're simply not getting them.

This article can't replace a doctor or a nutritionist, but it offers a comprehensive starting point for anyone who needs it. You can do more digging and confirm what's here. You could also just make a list of all the things discussed here and take them to someone you trust, and go from there.

It's crucial for us to develop a range of treatments and therapies for Covid that go beyond the mainstream reliance on Paxlovid and vaccines, conveniently dominated by a single pharmaceutical company.

It won't last forever.

In fact, research has shown that Paxlovid leads increasingly to rebound infections in which "the virus can return unimpeded by the drug, bringing the risk of disease and even death."

That's the part left out by corporate media. Rebound doesn't simply mean another round of Paxlovid. It means decreased effectiveness.

It means evasion.

Just like our mediocre vaccines, Covid is developing resistance to Paxlovid. According to an article in Nature, researchers around the world are now quietly racing to develop alternatives. No doubt, viral evolution offers one of the unspoken reasons why many of us find it so hard to access the drug now. The elites are terrified of losing the thing that enables their denial and wishful thinking.

Here's what one researcher said:

“This type of approach helped to improve HIV drugs, and we think it’s a good way to improve antivirals against SARS-CoV-2,” says Sho Iketani, PhD, assistant professor of medical sciences at Columbia University’s Vagelos College of Physicians and Surgeons and Aaron Diamond AIDS Research Center, who co-led the research..."

Western countries are well behind the curve on these fronts. Japan now offers a drug called Xocova (ensitrelvir), arguably more effective than Paxlovid, and it's been sitting in the FDA approval queue for about a year. China approved HIV antivirals for Long Covid back in 2022. While some healthcare workers in Europe and North America know about combining and repurposing drugs, many of them are still busy pretending Covid is over.

It's time for government agencies to pull their heads out of the sand and do their jobs. If there had been more urgency over the last four years, and less favoritism toward one or two drug giants, we would already have these treatments deployed. As things stand, we need leaders to not only run these long overdue clinical trials but also prepare to scale up production considerably, while making sure that everyone has access, not just those with platinum insurance plans. We could already be doing that for emergency off-label use now. Why aren't we?

Although it's infuriating and demoralizing it took us so long to get here, it's encouraging to know that teams of scientists around the world have been working on this crisis and producing results. We just need the gates unlocked.

There's no time to waste.

Let's get moving.

#covid #mask up #pandemic #covid 19 #wear a mask #coronavirus #sars cov 2 #still coviding #public health #wear a respirator

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reasonsforhope · 1 year ago

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"Five people have gone into remission thanks to advancements in medicine — and a sixth patient may also now be free of HIV.

One of the biggest breakthroughs in HIV/AIDS prevention in recent years is the widespread use of PrEP (pre-exposure prophylaxis).

This drug therapy, approved by the Federal Drug Administration in 2012, has been a key player in preventing HIV transmission through sex or injection drug use. Antiretroviral drugs, such as PrEP, also slow the replication of the virus and prevent it from progressing to AIDS.

Although PrEP has become a more accessible treatment for the virus, scientists have been hurriedly working towards cures for HIV for decades — and we’re finally seeing some results.

In February of this year, scientists in Germany confirmed a fifth-ever patient had been cured of HIV after receiving stem cell transplants that include genetic mutations that carry a resistance to HIV.

But it looks like a sixth patient may soon be able to join this very exclusive club.

The man, referred to as the “Geneva patient,” underwent a stem cell transplant after cancer treatment, though these cells did not include the HIV-resistant genetic mutation.

Still, he went off antiretroviral therapy for HIV in November 2021, and his viral load remains undetectable.

Instead, doctors are researching whether a drug called ruxolitinib may be partially responsible for his recovery.

Ruxolitinib decreases inflammation associated with HIV by blocking two proteins, JAK1 and JAK2. This helps kill off “reservoir cells” that lay dormant in the body and have a potential to cause rebounds in patients with HIV.

Experts say the AIDS crisis can end by 2030 across the globe — as long as leaders prioritize this goal.

A new report from UNAIDS shows a clear, optimistic path to ending the AIDS crisis. (This looks like a 90% reduction in cases by 2030.)

The organization’s report includes data and case studies that show that ending AIDS is a political and financial choice — and that governments that have prioritized a path towards progress are seeing extraordinary results.

By following the data, science, and evidence; tackling inequality; and ensuring sufficient and sustainable funding across communities, the global community could wipe out the AIDS pandemic by the end of the decade.

The report demonstrates that progress has been strongest in the countries and regions that have the most financial investments, like eastern and southern Africa, where new HIV infections have been reduced by 57% since 2010.

Investments in treatments, education, and access to care have also led to a 58% reduction in new HIV infections among children from 2010 to 2022 — the lowest number since the 1980’s.

Plus, the number of people on antiretroviral treatment around the globe has risen from 7.7 million in 2010 to 29.8 million in 2022.

The moral of the story? This goal can be achieved, if world leaders put their minds — and wallets — to it.

A region in Australia might be the first place in the world to reach the United Nations targets for ending HIV transmission.

Researchers believe that the central district of Sydney, Australia is close to becoming the first locality in the world to reach the UN’s target for ending transmission of HIV.

Specifically, new infections among gay men have fallen by 88% between 2010 and 2022. In fact, there were only 11 new HIV cases recorded in central Sydney last year, and almost all HIV-positive Australians are on antiretroviral drugs.

... "These numbers show us that virtual elimination of HIV transmissions is possible. Now, we need to look closely at what has worked in Sydney, and adapt it for other cities and regions across Australia.”

Namibia is ahead of schedule in UN targets to end HIV/AIDS.

Although the virus is still the leading cause of death in Namibia, the country is well on track to hit 95-95-95 UNAIDS targets before its 2030 deadline.

In Namibia, 92% of people know their HIV status, 99% of people living with HIV are on treatment, and 94% of people living with HIV who are on treatment are virally suppressed.

In addition to these exciting statistics, new infections have plummeted. The estimated rate of new HIV infections in Namibia is five times lower than it was in 2002, according to the Centers for Disease Control & Prevention.

These encouraging numbers are thanks to the investment and strategic response of PEPFAR, but also to the willingness of local governmental agencies and organizations to adhere to the UN’s Fast-Track approach.

Breakthroughs are being made in HIV vaccine therapies.

Long before we were all asking each other “Pfizer or Moderna?” about our COVID-19 vaccines, scientists have been researching the potential of mRNA vaccines in treating some of the world’s deadliest diseases — like HIV.

And with the success of our mainstream mRNA vaccines, an HIV inoculation remains a goal for researchers across the globe.

Last year, the National Institutes of Health launched a clinical trial of three mRNA vaccines for HIV, and similar studies are being conducted in Rwanda and South Africa, as well.

CAR T-cell clinical trials are underway to potentially cure HIV.

This spring, UC Davis Health researchers have dosed the second participant in their clinical trial, which poses the use of CAR T-cell therapy as a potential cure for HIV.

The study involves taking a participant’s own white blood cells (called T-cells), and modifying them so they can identify and target HIV cells, ultimately controlling the virus without medication.

The first participant in the study was dosed with anti-HIV T-cells last August, and the trial is the first of its kind to utilize this technology to potentially treat HIV.

Of course, the trials have a long way to go, and the lab is still preparing to dose a third participant for the study, but CAR T-cell treatments have been successful for lupus and forms of cancer in the past...

“So far, there have been no adverse events observed that were related to the treatment, and the two participants are doing fine.”

Guidance on how to reduce stigma and discrimination due to HIV/AIDS is reaching people around the globe.

While the stigma surrounding HIV and AIDS has significantly decreased — especially towards the LGBTQ+ community — with advancements in treatment and prevention, discrimination is certainly not gone.

While most people now understand HIV/AIDS better than they did decades ago, those most impacted by the virus (like gay men and low-income women and children) still face ongoing barriers to care and economic security.

It is vital to maintain awareness and education interventions.

After all, experts suggest that eliminating discrimination and stigma are key factors in reducing disease. And not eliminating stigma impedes HIV services, argues UNAIDS, “limiting access to and acceptance of prevention services, engagement in care, and adherence to antiretroviral therapy.”

Luckily, UNAIDS provides guidance on how to reduce stigma and discrimination in the community, workplace, education, health care, justice, and emergency settings.

The goal is to, of course, decrease stigma in order to decrease disease, but also to provide folks with the culturally significant support they need to live safe, integrated lives — with or without disease.

For instance, a 2022 study conducted in Northern Uganda showed that local cultural knowledge passed through Elders was a successful intervention in reducing HIV-related stigma among young people.

“Research in school settings has shown that the use of local cultural stories, songs, myths, riddles, and proverbs increases resilient coping responses among students and strengthens positive and socially accepted morals and values,” the study’s discussion reads.

So, while an uptick in acceptance gives us hope, it also gives us a directive: Keep telling the accurate, full, and human stories behind HIV/AIDS, and we’ll all be better for it. "

-via GoodGoodGood, August 3, 2023

#hiv #hiv/aids #aids crisis #public health #medical research #vaccines #australia #namibia #united nations #queer issues #trans issues #lgbtq issues #lgbtq community #infection prevention #good news #hope

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letters-to-lgbt-kids · 2 years ago

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(TW: Sex - educational context, HIV prevention)

My dear lgbt+ kids,

After my last post about HIV, I received multiple asks like "I feel embarrassed to ask something so stupid but..." - and the pure fact that I got multiple of them already proves that not knowing something is no reason to be embarrassed!

Many people are not super confident in their HIV knowledge. Acknowledging that and seeking more info is a great thing. I decided to put all these questions in one post:

How do you even get HIV?

Certain body fluids can transmit HIV:

blood

semen (cum)

pre-seminal fluid (pre-cum)

rectal fluids

vaginal fluids

breast milk.

Most adults who get HIV get it through sex (vaginal or anal) or sharing needles (or other drug injection equipment). Getting it from oral sex is also possible but less common.

Parent-to-child transmission (birth, breastfeeding) is the most common way that children get HIV.

Can you get HIV from topping?

Yes. Both the top and the bottom can get HIV through penetrative sex (top means you are penetrating your partner, bottom means your partner is penetrating you).

During anal sex, the bottom has a higher risk. That's because HIV can enter the body through the rectum’s thin lining. But: HIV can also enter the body through the opening at the tip of the penis or the foreskin or small cuts/scratches/sores anywhere on the penis.

During vaginal sex, either partner can get HIV as well, through vaginal tissue, the cervix or the penis as described above.

Can you get HIV from kissing?

You can’t transmit HIV through saliva, so there would need to be blood (or another fluid of the ones named above) involved. That means you could theoretically get HIV from open-mouthed kissing if both partners have sores or bleeding gums - but this is very rare.

You can’t transmit HIV at all through closed-mouthed kissing.

Can you get HIV from a public toilet?

The only realistic risk of getting HIV from a public toilet is by having sex or sharing drug equipment in there!

HIV does not survive long outside the human body (like on the toilet seat or door handle) and it cannot reproduce outside a human host. Wash your hands, as there are other germs that do survive on surfaces, but don't worry about HIV.

Can you get HIV from getting a tattoo?

You theoretically could - if the equipment or ink has someone else’s blood in it. This is unlikely to happen unless the person doing your tattoo uses unsterilized needles.

If you get a tattoo or piercing, make sure that the person doing the procedure is properly licensed and uses only new or sterilized equipment.

Can you get HIV from masturbating?

No. The only possible way would be if there were bodily fluids from an infected person on your fingers or sex toys.

It's always a good idea to wash your hands first because there could be other germs/irritants on them - but if you are doing it all alone, there is no risk of HIV. If you are masturbating together with another person, try to avoid sharing toys. If you do share them, use a new condom for each partner.

Can you get HIV from drinking alcohol?

When we talk about transmission via drug use, we are talking about sharing needles or drug equipment - they may have someone else's blood on them.

Alcohol use doesn't involve needles, you can not directly get HIV from being drunk. But: being drunk (or high) can lead to risky behavior that sober you wouldn't participate in, such as unprotected sex! It's a good idea to be careful around alcohol.

Isn't there a cure for HIV by now?

No. Once you have HIV, you have it for life - but the good news are there is treatment available! Someone who is HIV-positive and starts receiving treatment early has a normal life expectancy.

Medicine can reduce the amount of HIV in the blood (this is called viral load). In fact, it can make the viral load so low that a test can’t detect it anymore - and if you have an undetectable viral load, you will not transmit HIV to others!

With all my love,

Your Tumblr Dad

#lgbt #lgbt+

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theside-b · 30 days ago

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Just finished Love In The Big City and I don’t know, it’s a sad story but I don’t feel crushed by it nor wanted a pretty little bow in the form of a “happy ending” for it.

I didn’t read the book so I’m basing on the show only: the ending was fitting. Though they could’ve explored a few things better, some nice ideas that were not fully fleshed out in the final episodes.

Now, the production value here? Whew, it leaves an impression, and so does the acting, role of a lifetime for Yoonsu — threw himself in this role, his Young feels authentic, real, he brings his A game and uses it to the max.

Personally, an important part of the story was jarring for the wrong reasons (to me). Everything surrounding Young’s status as HIV-positive left me shocked by the way they deal with it in South Korea (assuming the show portrays accurately), because from where I’m from it’s not handled that way at all, with patients having access to meds that lower the viral load to undetectable levels and alternative for the partners to prevent infection through sex, all of that for free, I was surprised seeing them dealing with his condition that way. Cultural difference that really made a difference for me here. Young and Gyu ho would hardly have the problems they did in the show with the right medical counseling.

Other than that I thought it was lovely show, albeit melancholic and moody — it’s like the sad gay cousin of Sex and the City. It’s witty, sexy, well acted and barely avoiding depression.

#love in the big city #bl review #hopefully this one does waves #and help kbls get out of this funk

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meanmisscharles · 2 years ago

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OKAY SO IT'S WORLD AIDS DAY, BABES

First of all, I'm going to just talk about KNOWING YOUR STATUS!

"Why, Meanmisscharles?"

BECAUSE KNOWING YOUR STATUS IS SUPER FUCKING IMPORTANT, EVEN IF YOU DON'T THINK IT IS.

Being tested for HIV (and other blood-borne viruses, like Hepatitis C) is the first step in AIDS prevention. You should get tested if you're having sex right now, if you've had sex, or if you think maybe you might have sex. You should also get tested if you've used syringes for substance use, are using syringes, or might use syringes for substance use, or are partners with someone that does. You can also acquire HIV from shared piercing and tattoo needles.

You should know YOUR status, even if you don't know your partner's status. Some testing centers offer couple's testing - but make sure that option is one that you feel safe and comfortable doing.

A "non-reactive" or "negative" HIV test means that you can get on PrEP and keep your status that way, with correct and regular use.

A "reactive" or "positive" HIV test means that you can start ART (anti-retroviral treatment) that with regular and correct use, can bring your status to "undetectable" - which means that your viral load is undetectable on standard blood tests and you won't pass HIV to partners through sex.

Knowing your status so you can take steps to prevent transmission, or start treatment, is about empowering yourself.

Find out where you can get free HIV testing here:

Freehivtest.net

Helpstopthevirus.com

I know all the smart young people following me know this, but I still wanted to put something out there. I remember what it was like, before testing was available and I remember the people that fought so hard for this to be different than it was then.

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queerism1969 · 1 year ago

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Things you should know before having SEX

There is absolutely nothing rude or accusatory about asking a new partner about their STD history

Use both a barrier method (male or female condom) AND a hormonal method for the best bet at preventing pregnancy

When you’re considering stopping using condoms with a partner, you can ask them if you can go together to get tested first

Don’t have sex with anyone who would hesitate to slow down or stop if you want to or who would be angry or upset with you because of it

Get tested regularly, every 1–3 months

You can go on PrEP if you feel you are truly at risk of getting HIV

Look at your partner and make sure they do not have cold sores, if they do, don’t kiss/do oral with them!

Always meet in public first

Have boundaries and don’t be afraid of kicking someone out/leaving

It’s easier and cheaper to change condoms than diapers.

If you're planning on having a lot of casual sex, you must accept that you will be exposed to STIs.

There is no such thing as safe sex - just risk reduced.

Pinch the reservoir tip of a condom as you slide it down the penis to make sure there is enough space for the semen to collect

Oral/vaginal/anal sex all have STD risks.

Do NOT use oil-based lubricants with a condom

Abstinence-only is a terrible idea, and statistics show it: STD rates and teen pregnancy rates are higher in areas with abstinence-only sex education programs.

Some people enjoy a little acting or role-playing during sex so it helps to have a pronounced safe word that nobody will say by accident.

Don't dominate on the first physical meeting.

Don't introduce new, undiscussed elements into a scene in the heat of the moment.

Dental dams for oral sex, surgical gloves with LOTS of lubes for fingering, trim your nails, and wash your hands.

Vagina penetration isn't going to be as easy, like they show in porn

it's essential to clean off the semen before putting on another condom.

Buy plenty of condoms

Pee after sex as it is important to prevent UTI.

Throw out everything you see in porn, it's unrealistic and most of the positions are not possible or enjoyable as they look on camera.

Have plenty of foreplay before penetration

When you get on the pill, ask your doc how long that pill takes to be effective.

Cum will drip out of you, and you will look silly waddling to the bathroom to go pee and clean up

If you take any kind of antibiotics, it will render your birth control pills ineffective for the rest of that month.

Never be ashamed to have cleanup supplies near your bed.

Doing kegel squeezes in the restroom really helps push most if not all the cum out.

Two people with a vulva can give each other STIs.

Let someone know where you are and when you'd be back.

Your hookup doesn't have to be for penetrative sex

Don't drink anything you're handed that you don't see poured and doesn't leave your sight.

Oral sex is very risky for things like gonorrhea, chlamydia, and syphilis (especially syphilis and pharyngeal gonorrhea).

Asking for Snapchat always does a good job of weeding out the fakes.

Always bring your own condoms and lube

Always let the person know that you’ll only have sex with condoms before meeting up

Obtain pepper spray just in case you’re put in a dangerous situation.

Clean your toys appropriately, and make sure it's body-safe material (if it starts to smell even after cleanings, throw it away).

Be sure to use the correct kind of lube

For any kind of sex, there generally shouldn't be pain. If there's pain, something is probably wrong.

If you brush your teeth before doing oral, wait till the minty flavor is gone before going down on them

Your pubic hair is normal and healthy. Trimming is fine, shaving I recommend a lot less.

Sex is a marathon, not a sprint

Not liking sex is okay.

HIV is no longer a death sentence. With proper treatment, your viral load can be so low that transition is impossible. You'll have to manage it for the rest of your life, and your partners would have to take PREP and HIV prevention drugs.

If you decide to practice kink, be aware that consent becomes much more explicit and requires a lot of prep to properly establish. Without consent, it's just abuse.

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mindblowingscience · 1 year ago

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Now an international team of researchers has discovered a new genetic variant in people of African ancestries that appears to restrict HIV replication after an infection sets in. Though more research is needed to confirm their findings, the discovery is a huge step forward for HIV research, which has long neglected African populations. "The findings may explain why certain people in these populations have a lower viral load, which slows down the virus from replicating and transmitting," says pathologist and study author Simon Mallal from Murdoch University in Perth, Australia. The discovery, from a combined analysis of nearly 3,900 individuals, could also pave the way to developing new antiviral drugs as previously identified genetic variants have done in the past.

#science #stem #health #medicine #genetics #virology #hiv

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sunflowers666 · 4 months ago

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Been living with HIV for nearly a decade. You will feel pretty crappy for a while even when you are undetectable. Once your body sorts everything out you will be right as rain with a few time you feel icky here and there. The better news is that the CDC has stated transmission from sexual fluids is impossible with an undetectable viral load. Steer clear of alcohol within a few hours of taking your pills and if you take anything for heartburn (not tums or anything like. Stuff like nexium or Prevacid) then make sure you take your anti-retrovirals first then and then wait two hours before you take the heartburn stuff. Take your stuff religiously and you and your girlfriend will be perfectly safe.

this ask made me kinda upset when i got it. .. i have known abt everything u said. i was posting at the time abt being stressed abt access to medications. having hiv does affect how ppl want to interact w me sexually even if i am undetectable. the acute infection did change me forever, i am weaker now. im nauseous all the time... "Long term toxicological effects of antiretroviral treatments can sometimes cause secondary morbidities even when the viral count is low." idk.. whatever, hope u survive

also fuck the cdc

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pierayanna · 10 months ago

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COVID-19

We are currently in the largest COVID surge of all-time in the US.

There is also a new variant that is not protected by the previous vaccine.

Please start back masking and please get the COVID-19 booster (schedule with your local pharmacy).

Wastewater counts are obscenely high right now, belying the official case numbers. Considering that we've stopped collecting or reporting most COVID data, wastewater is the best way we have to judge the actual infection rate now. Wastewater is collected from washing our hands, going the bathroom, etc. We shed COVID into the water system and based on the concentration of COVID in waste water, we can get very accurate estimates of how many people are infected at one time.

We are currently seeing ten million new infections a week, and can expect that to greatly increase within the next three weeks.

* If you've stopped masking, please start again, for your own safety and the safety of your community. Many hospital systems are already trending toward being overwhelmed right now; wear a mask when in crowded, enclosed, or poorly ventilated areas, and keep a safe distance from others, as feasible.

* Avoid unnecessary gatherings where possible.

* Ventilate your spaces well (Corsi-Rosenthal Box).

* Reevaluate casual habits (touching face, respiratory etiquette—covering coughs and sneezes, clean your hands regularly, stay home if you are sick, get tested if you have symptoms, or if you might have been exposed to someone with COVID-19 or influenza)

Please be aware of Long Covid.

COVID impacts the immune system similar to HIV in that it hides in the body and continues to wreak havoc in the various organ system by driving inflammation and disrupting the immune response. It causes neurological, vascular, and immune dysfunction.

Patients with long COVID generally have symptoms that fall into three categories or phenotypes: fatigue, neurocognitive symptoms such as brain fog or headaches, and cardiovascular symptoms such as shortness of breath, heart arrythmias, exercise intolerance, and blood clots. Patients may have more than one type, and some also have symptoms like constipation, diarrhea, or loss of taste and smell that don’t seem to fit neatly into one of the three groups.

This is a period where we need to act with more care. Not a time to panic, but a time to be more cautious.

If you contract COVID, these are some helpful things that work to reduce viral load in the hope of minimising symptoms. And your chance of developing Long Covid:

* Brush & floss as usual

* Mouthwash (CPC (cetylpyridinium chloride, an ingredient in many/most commercial mouthwashes), cooled green tea, salt water)

* Green Tea (drink on an empty stomach if possible; can also be used for swishing/gargling once it has cooled; if green tea isn't doable for you, black tea is an alternative)

* Nasal Spray (if chemicals in nasal spray causing an issue for you, saline nasal spray also an option)

* Vitamin C supplement

* Antihistamines

* Other prophylactics to consider: Nattokinase, Grape Seed Extract, EGCG supplements

* Natto (if this is something you already eat, or would like to try. It's fermented soya beans and is popular in Japan

* Mask & Vaccinate!! A fully vaccinated individual is five times less likely to continue to have any symptoms or ill-effects three months after their initial infection compared to someone who has not been vaccinated.

Not a medical professional but compiled resources from medical professionals and individuals with disabilities including long COVID.

Free Palestine. Free Congo. Free Sudan. Free Tigray. Stop Cop City. Eyes on the Mass Graves in Jackson.

Please SHARE & Please participate in the Global Strike for Palestine 1.21-1.28.

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