#viral load

[pandemic-info]

COVID patients breathe large amounts of virus early on - Northwestern Now

It is the first longitudinal, direct measure of the number of SARS-CoV-2 viral copies exhaled per minute over the course of the infection — from the first sign of symptoms until 20 days after. On day eight, exhaled levels of virus drop steeply, down to near the limit of detection — an average of two copies exhaled per minute. Northwestern investigators tested breath samples — collected multiple times daily from 44 individuals — over the entire course of infection to determine when a person is most infectious.

...

“The vast majority of research on viral loads over the course of a COVID-19 infection has been based on nasal or oral swabs, which measure virus in the nose or throat,” said lead study author Gregory Lane, senior research project manager in Zelano’s lab. “However, SARS-CoV-2 is spread through breath, and virus on the breath may not match virus in the nose. The dynamics of viral shedding on breath over the course of infection are poorly understood, despite the fact that this is how the virus spreads.”

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[fidicushiv]

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[nowstomorrow]

Very interesting study on the amount of viral particles expired throughout infection!

“The vast majority of research on viral loads over the course of a COVID-19 infection has been based on nasal or oral swabs, which measure virus in the nose or throat,” said lead study author Gregory Lane, senior research project manager in Zelano’s lab. “However, SARS-CoV-2 is spread through breath, and virus on the breath may not match virus in the nose. The dynamics of viral shedding on breath over the course of infection are poorly understood, despite the fact that this is how the virus spreads.”

“For example, if we assume the infectious dose for COVID is 300 copies, then a person who is exhaling 1,000 viral copies per minute would exhale an infectious dose in 20 seconds (highly risky in an elevator), whereas a person who is exhaling two viral copies per minute would exhale an infectious dose in about two hours (probably safe in an elevator),” Lane said. It is not yet known what an infectious dose of viral airborne particles is.

“Once you can answer the question of how many viruses you are exhaling for each day after your symptoms start, critical pieces of the puzzle of how to avoid the spread of COVID-19 fall into place,” Lane said. “This information speaks directly to when someone with COVID-19 should isolate; when they are more likely to infect other people by breathing out virus into the air around them; and when they become much less likely to spread the infection. These two pieces of information are very important for infection control and for informing public health recommendations.” The study measured virus on breath from the first day symptoms start, which is day zero. From that day until day eight, infected people exhaled lots of virus, the scientists found. The amount varied, with peaks of 1,000 viral copies a minute, but the average was high. Then, on day eight, it dropped steeply to levels that hovered around the limit of detection (about two copies a minute), with few exceptions.

[plant-bioreactor-answers]

Okay, so one of my Weird Plant Stories is a tradition among high-level engineers that began on Old Earth but has adherents in... probably every SEEDS ship. Let us call it "Spontaneous Machine-Religion." If humans are not given a religion to follow, it seems like they'll inevitably make it up and Plants HELP. No, I am not talking about out and out Plant-cults you might have heard of, but something far stranger and coming from SCIENTIFIC minds. So, some Plants are open to receiving sacrifices. I've seen it myself. What I mean is, some caught on that some Plants will have a higher output of their specific creation if the people who are watching them do something a little superstitious. This stuff always starts as pranks and jokes. The "Let's tell the guy who's a virgin that we need to prick his finger because the Plant runs on the blood of virgins" or "We need to burn this donut from our morning work-dozen at the foot of the Plant bulb on an altar to show her that she is our co-worker." Maybe they do not eat and technically do not require anything in tribute, but the Plants become USED to it. I think they develop a feeling of contentedness to their engineers this way, it makes them feel acknowledged. Because it WORKS. Whenever - down to the last Plant - a Plant that has been given little tributes stops receiving tribute for whatever reason - a hard new boss, a lack of resources, the office virgin getting a girlfriend, whatever... the Plant lowers their output. Without fail. Sometimes they even do less output than original programming or they get...finicky... and problems arise in the system. Older engineers try to tell newer ones "don't even start" with the silly altar-tribute games because once it starts, it will not end. _ R. S.

[zenon-karr]

POV you’re buddie and you find out on Chim’s phone your drunk karaoke video went viral and you called it ‘Buddie- What I like About You:

[meezer]

woke up coughing due to the sorest throat known to man

[hvlthgxth]

Borkfast.

[princehendir]

This is kind of an awful thing to say but as someone who's taken A Lot of rapid tests over the last two weeks I'm starting to feel like those super-faint lines that people keep reporting on twitter is a like, skill issue

[eirianerisdar]

A little "good luck" for lunar new year for all medical professionals like me:

龍年大吉 (Good fortune in the Year of the Dragon) 生意淡薄 (May your business be thin and little) 準時收工 (Leave work on time)

[pandemic-info]

Viral shedding by asymptomatic people may represent a subset of total infections, but uncertainty remains regarding how much they contribute to totals.

Viral shedding may antedate symptoms, usually two days.

Viral titers are highest in the earliest phases of infection, 1-2 days before the onset of symptoms, and then in the first 4-6 days of illness in patients without immunosuppression.

When Is COVID-19 the Most Contagious?

Researchers estimate that people who get infected with COVID-19 can spread it to others 2-3 days before symptoms start and are most contagious 1-2 days before they feel sick.

&

How long after exposure will you test positive for COVID-19?

Depending on which COVID-19 variant you've been exposed to, you may test positive 3-5 days later. If you've been exposed to the virus but don't have any symptoms, wait for 5 days before you get tested. If you test too early and you do have COVID-19, you may falsely test negative.

[fastwalker]

so covid blisters isn't a symptom I had last time

love having atypical symptoms doctors will call you insane over if you dare to bring them up <3

[downfallofi]

I wanna be off quarantine so fucking bad but the test I took has just the faintest positive line and it made me want to punch my stupid, stupid body right in the stomach

[umbrellacorphq]

Employees are reminded that leaving food in the fridge, injecting yourself with expensive viral loads, and wearing open-toed shoes have all now been added to the conduct documentation and are not permitted.

[millerflintstone]

Sometimes I feel ok. Sometimes my nose is super runny but then stops. Sometimes I'm so tired I just fall asleep. Sometimes I'm too tired to sleep.

It's like this crap has multiple personalities. Unfriendly's symptoms are similar. I did pick up more rapid tests to check again

[funnuraba]

Watching creator after creator, from professionals to twitch streamers on down, post about how they’re really weirdly sick with cold/flu and medications aren’t helping, and knowing a huge number of them have Covid that they’re gonna keep spreading for weeks after “recovering” because they have no idea they should be testing or masking

[oddside]

big vaxxed papi no longer untouchable :(