#Improve Insulin Sensitivity

[mehmetyildizmelbourne-blog]

Here’s Why and How to Shift from a Sugar to a Fat-Burning Metabolism

Regardless of age, when our body is fat-adapted, it can effortlessly generate energy from sugar and fat, giving us a better metabolic position and a defined body.  A long time ago, when struggling with metabolic issues, I learned that anthropological studies indicated that humans survived famines and evolved by gaining fat-adapted bodies. When studying mechanisms, I found that gluconeogenesis…

[funsimplethings]

[myhealthstore]

Diet for type 2 diabetes - A healthy diet is essential for managing type 2 diabetes...

Type 2 diabetes is a chronic condition that affects millions of people around the world. The primary cause of this disease is insulin resistance, which means that your body cannot use insulin properly. This results in high levels of glucose in the blood, leading to various health complications. Diet plays a crucial role in managing type 2 diabetes, and it is important to follow a healthy eating plan that is rich in nutrients, vitamins, supplements, and minerals. Visit..

Here are some essential dietary recommendations for people with type 2 diabetes:

Focus on Whole Foods Whole foods are nutrient-dense and provide a range of health benefits. They are typically low in calories, high in fiber, and contain essential vitamins and minerals. Eating whole foods can help to manage blood glucose levels and promote overall health. Some examples of whole foods include fruits, vegetables, whole grains, lean proteins, nuts, and seeds. Discover!

Avoid Processed Foods Processed foods are often high in sugar, salt, and unhealthy fats. They can cause spikes in blood glucose levels and increase the risk of health complications associated with type 2 diabetes. Examples of processed foods include fast food, pre-packaged meals, and sugary snacks. It is best to avoid these types of foods and choose whole, unprocessed alternatives instead.

Choose Low-Glycemic Index Foods The glycemic index (GI) measures how quickly a food raises blood glucose levels. Foods with a high GI can cause blood sugar spikes, while foods with a low GI can help to regulate blood sugar levels. Some examples of low-GI foods include beans, lentils, whole grains, non-starchy vegetables, and fruits.

Supplement with Vitamins and Minerals People with type 2 diabetes may be deficient in certain vitamins and minerals, such as vitamin D, magnesium, and chromium. Supplementation with these nutrients can help to improve blood sugar control and reduce the risk of health complications. Consult with a healthcare provider to determine the appropriate dosage and type of supplements that are best for you.

Consider Herbal Supplements Some herbs and supplements, such as cinnamon, alpha-lipoic acid, and berberine, may help to improve insulin sensitivity and reduce blood glucose levels. However, it is important to consult with a healthcare provider before taking any herbal supplements, as they may interact with other medications or have side effects.

In conclusion, a healthy diet is essential for managing type 2 diabetes. It is important to focus on whole foods, avoid processed foods, choose low-GI foods, supplement with essential vitamins and minerals, and consider herbal supplements. By following these dietary recommendations, people with type 2 diabetes can help to regulate blood sugar levels, improve insulin sensitivity, and reduce the risk of health complications associated with this condition. Get..

[willowsearth]

Insulin Resistance: What it is and How to Reverse it

Insulin is a hormone produced by your pancreas that plays a crucial role in regulating your blood sugar levels. When you eat carbohydrates, your body breaks them down into glucose, which is then absorbed into your bloodstream. Insulin helps your cells take up glucose and use it for energy. However, if you eat too many carbohydrates or have a diet high in processed foods and sugars, your body may…

[smartweightlosstip]

1️⃣ Encourages Fat Burning: "By cutting carbs, your body shifts to burning fat for fuel, leading to faster fat loss." 2️⃣ Reduces Hunger: "Low-carb meals stabilize blood sugar levels, curbing cravings and keeping you satisfied for longer." 3️⃣ Improves Insulin Sensitivity: "Lowering carb intake can enhance insulin function, helping your body manage glucose efficiently and reducing fat storage." Examples of Low-Carb Foods: Proteins: Chicken, eggs, fish, and lean beef. Healthy Fats: Avocados, olive oil, and nuts. Low-Carb Vegetables: Broccoli, spinach, and cauliflower. When a Low-Carb Diet Works: "It works when you pair it with consistent meal planning and proper hydration. Incorporating vegetables ensures you get essential vitamins and minerals without the carb load." When It Fails: "A low-carb diet may fail when it lacks balance—cutting out carbs entirely can lead to fatigue or nutrient deficiencies. It's important to stay hydrated and add fiber-rich foods to prevent digestive issues." Beyond Weight Loss: Additional Benefits Better Mental Clarity: "Many people report improved focus and concentration with fewer carbs in their diet." Steady Energy Levels: "By avoiding carb crashes, you experience sustained energy throughout the day." Reduced Inflammation: "Lowering sugar and refined carbs helps decrease inflammation, promoting overall health

👉 Follow us for simple weight loss tips and healthy lifestyle habits to stay motivated on your journey!

Simple weight loss tips Diet for weight loss Low-calorie recipes Healthy lifestyle habits Quick weight loss tips #InsulinResistance #WeightLossTips #HealthyLiving #TopDiets #WeightLossMotivation #WeightLossTransformation #FatBurning #DropThePounds #ShedTheWeight #BurnFat #Simpleweightlosstips #Dietforweightloss #Low-calorierecipes #Healthylifestylehabits #Quickweightlosstips

[justposting1]

What Happens to Your Body When You Quit Sugar For 30 Days?

Sugar is a common part of many diets, but it’s also linked to a host of health issues when consumed in excess. For many, cutting out sugar can seem like a daunting task, but doing so can lead to remarkable changes in your body. Here’s what you can expect if you stop consuming sugar for 30 days. Week 1: Withdrawal Symptoms and Cravings The first week of quitting sugar can be challenging as your…

[diabetesreversalprograminindia]

Chia seeds benefits for diabetes

This article is originally published on Freedom from Diabetes website, available here. We always listen like Chota packet bada dhamaka. Here is also same like this with chia seeds. Chia seeds are one of thems. Chia seeds are small seeds black in color obtained from the plant Salvia hispanica. It is an important food due to its ability to provide sustainable energy. The fact is it has got its name “chia” from a Mayan word for “strength.”

Chia seeds are considered the healthiest foods on the planet. Do not go by their size they are Chota packet bada dhamaka with a pack of powerful nutritional punch.

First understand their nutritions details. Chia seeds and nutritions details 1 Ounce of chia seeds contain 137 calories, 11 grams fiber, 4 grams Protien, 9 grams Fat, 18% of the RDI Calcium, 30% of the RDI Manganese, 27%Phosphorus of the RDI. They also contain a good amount of vitamin B1, zinc, vitamin B3 (niacin), potassium, and vitamin B2. Now lets understand their benefits one by one.

Chia seeds benefits

Reduce Blood Sugar Levels Chia seeds play an important role in improving insulin sensitivity and blood sugar control by stabilizing sugar levels after meals thus benefitting people with type 2 diabetes.

Antioxidants Chia seed are of great help in protecting the delicate fats present in the seeds along with various health benefits.

Chia seed are good in carbohydrates, 28 grams chia seed give us 12 gram of carbs.

Chia seeds have a good amount of protein as compared to plants. The essential amino acids present in the chia seeds which help the right usage of this protein. These quality are helpful for the weight loss.

Reduce Chronic Inflammation Inflammation is the body's normal response to infection or injury. Chronic inflammation can cause a lot of harm in the form of increased risk of heart disease and cancer. Regular use of chia seed, reducing inflammation thus useful in diabetes.

So You can have chia seeds in the raw form or soaked and used in a smoothie also. One can sprinkle them on salads.

If you have not included chia seeds in your diet yet, start adding them from toady.

If you want to learn more about this, please click here. Also please connect with me on my website, Facebook page, and YouTube if you want to stay in touch or give me any feedback!

[wellextol]

Sugar Balance Review - Exploring the Potential of This Blood Sugar Stabilization SupplementBalancing blood sugar levels is crucial to overall health, particularly for individuals struggling with insulin resistance or those aiming to prevent such conditions. Sugar Balance, a supplement designed for blood sugar stabilization, has gained attention in this context. Examine Sugar Balance to determine its efficacy in managing blood sugar levels and reducing insulin resistance.

[reasonsforhope]

A new treatment combining ReCET and semaglutide could eliminate the need for insulin in type 2 diabetes, with 86% of participants in a study no longer requiring insulin therapy. The treatment was safe and well-tolerated, and further trials are planned to confirm these results.

Groundbreaking research presented at UEG Week 2024 introduces a promising new treatment approach for type 2 diabetes (T2D) that has the potential to greatly reduce or even eliminate the need for insulin therapy.

This innovative approach, which combines a novel procedure known as ReCET (Re-Cellularization via Electroporation Therapy) with semaglutide, resulted in the elimination of insulin therapy for 86% of patients.

Globally, T2D affects 422 million people... While insulin therapy is commonly used to manage blood sugar levels in T2D patients, it can result in side effects... and further complicate diabetes management. [Note: Also very importantly it's fucking bankrupting people who need it!!] A need therefore exists for alternative treatment strategies.

Study Design and Outcomes

The first-in-human study included 14 participants aged 28 to 75 years, with body mass indices ranging from 24 to 40 kg/m². Each participant underwent the ReCET procedure under deep sedation, a treatment intended to improve the body’s sensitivity to its own insulin. Following the procedure, participants adhered to a two-week isocaloric liquid diet, after which semaglutide was gradually titrated up to 1mg/week.

Remarkably, at the 6- and 12-month follow-up, 86% of participants (12 out of 14) no longer required insulin therapy, and this success continued through the 24-month follow-up. In these cases, all patients maintained glycaemic control, with HbA1c levels remaining below 7.5%.

Tolerability and Safety

The maximum dose of semaglutide was well-tolerated by 93% of participants, one individual could not increase to the maximum dose due to nausea. All patients successfully completed the ReCET procedure, and no serious adverse effects were reported.

Dr Celine Busch, lead author of the study, commented, “These findings are very encouraging, suggesting that ReCET is a safe and feasible procedure that, when combined with semaglutide, can effectively eliminate the need for insulin therapy.”

“Unlike drug therapy, which requires daily medication adherence, ReCET is compliance-free [meaning: you don't have to take it every day], addressing the critical issue of ongoing patient adherence in the management of T2D. In addition, the treatment is disease-modifying: it improves the patient’s sensitivity to their own (endogenous) insulin, tackling the root cause of the disease, as opposed to currently available drug therapies, that are at best disease-controlling.”

Looking ahead, the researchers plan to conduct larger randomized controlled trials to further validate these findings. Dr. Busch added, “We are currently conducting the EMINENT-2 trial with the same inclusion and exclusion criteria and administration of semaglutide, but with either a sham procedure or ReCET. This study will also include mechanistic assessments to evaluate the underlying mechanism of ReCET.”

-via SciTechDaily, October 17, 2024

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Note: If it works even half as well as suggested, this could free so many people from the burden of the ongoing ridiculous cost of insulin. Pharma companies that make insulin can go choke (hopefully).

[wellhealthhub]

A Comprehensive Guide to Managing Diabetes with Effective Medications

Greetings and welcome to our meticulously crafted and all-encompassing guide on the management of diabetes utilizing an array of highly effective medications. This profound and pervasive chronic condition impacts millions of individuals worldwide, necessitating scrupulous and unwavering attention to achieve optimal health and contentment. This article embarks on an odyssey, delving into the…

[diabetesknow]

Intermittent Fasting - Everything You Should Know - Diabetes Knowledge

[suchananewsblog]

6 Foods That Will Help You Combat Insulin Resistance, As Picked By A Nutritionist

If you suffer from insulin resistance, it means that your body is not responding to this crucial hormone properly. This implies that glucose is not entering our cells as usual, leading to an increase in blood sugar levels, among other complications. Research has shown that this can put you at risk of Type 2 diabetes. In the long term, insulin resistance may also lead to heart disease, PCOS and…

[fullgossip]

The Benefits of Keto: How Eating the Right Foods Can Change Your Life

The Benefits of Keto: How Eating the Right Foods Can Change Your Life is a comprehensive guide to the keto diet, a dietary approach that has been gaining popularity in recent years. In this book, you will learn about the basics of the keto diet, including its macronutrient ratios and the science behind how the diet works.

But this book is about much more than just the basics of the keto diet. It explores the many benefits of the keto diet for weight loss, cardiovascular health, blood sugar and insulin levels, brain health, and more. Each chapter is dedicated to a different aspect of the keto diet and its impact on overall health and well-being.

Chapter 1 explores the basics of the keto diet and how it works, including the macronutrient ratios that are required to achieve ketosis. This chapter provides a solid foundation for understanding the rest of the book and the science behind the keto diet.

Chapter 2 delves into the many benefits of the keto diet for cardiovascular health. By promoting the consumption of healthy fats and reducing the intake of carbohydrates, the keto diet can lead to improvements in cholesterol levels, reduced inflammation, and a lower risk of chronic diseases such as heart disease.

Chapter 3 explores the effectiveness of the keto diet for weight loss. By reducing overall calorie intake, promoting the consumption of healthy fats and moderate amounts of protein, and promoting the breakdown of stored body fat for fuel, the keto diet can lead to greater weight loss and improved overall health and well-being.

Chapter 4 delves into the impact of the keto diet on blood sugar and insulin levels. By reducing carbohydrate intake and promoting the breakdown of stored body fat for fuel, the keto diet can improve insulin sensitivity and reduce the risk of type 2 diabetes.

Chapter 5 explores the many benefits of the keto diet for brain health. By promoting the production of ketones for energy, the keto diet can improve cognitive function, provide neuroprotection, and be beneficial for people with certain neurological conditions.

Chapter 6 separates fact from fiction when it comes to common myths and misconceptions about the keto diet. This chapter explores some of the most common myths and misconceptions about the diet and provides evidence-based information to help readers make informed decisions about the keto diet.

The Benefits of Keto: How Eating the Right Foods Can Change Your Life is a comprehensive guide to the keto diet and its many health benefits. Whether you are interested in losing weight, improving cardiovascular health, or promoting overall health and well-being, this book provides evidence-based information and practical advice to help you achieve your goals. By following a balanced and sustainable approach, the keto diet can be a safe and effective way to achieve improved overall health and well-being.

Free download , no email required.

[healthylifeenjoy]

Gluco Shield Pro Supplements Health Product

used Gluco Shield Pro supplements for two months and found them to be a beneficial addition to my overall health regimen. This product is designed to support healthy blood sugar levels and promote overall well-being. In this review, I will share my personal experiences and insights into Gluco Shield Pro, including its benefits, ingredients, and usage.

Benefits of Gluco Shield Pro Gluco Shield Pro offers several potential benefits for individuals seeking to maintain healthy blood sugar levels. Firstly, the product contains a unique blend of natural ingredients that have been traditionally used to support metabolic health. These ingredients work synergistically to help regulate blood sugar levels and prevent spikes and crashes.

Secondly, Gluco Shield Pro may also contribute to improved energy levels and reduced fatigue. When blood sugar levels are balanced, the body can efficiently utilize glucose for energy production, leading to sustained mental and physical performance.

Ingredients Gluco Shield Pro is formulated with a carefully selected combination of natural ingredients, including:

Gymnema sylvestre: This herb has been traditionally used in Ayurvedic medicine to manage blood sugar levels. Gymnema sylvestre contains compounds that may help reduce sugar cravings and improve glucose absorption.

Bitter melon: Bitter melon is a tropical fruit with hypoglycemic properties. It contains substances that can help stimulate insulin production and increase glucose uptake by cells.

Cinnamon: Cinnamon is a spice with potential blood sugar-balancing effects. Studies have shown that cinnamon may improve insulin sensitivity and reduce fasting blood sugar levels.

Chromium: Chromium is a trace mineral that plays a role in glucose metabolism. It helps regulate blood sugar levels by enhancing insulin's effectiveness.

Usage Gluco Shield Pro comes in convenient capsule form. As per the manufacturer's recommendations, I took two capsules daily with meals. The capsules were easy to swallow and did not cause any digestive discomfort.

My Experience I have been using Gluco Shield Pro for the past two months and have noticed a positive impact on my overall health. My energy levels have increased significantly, and I no longer experience the same afternoon slumps as before. I also feel more mentally focused and alert.

While I cannot claim that Gluco Shield Pro has cured any underlying health conditions, I have observed a noticeable improvement in my blood sugar control. My occasional blood sugar readings have been within the normal range, and I have experienced fewer fluctuations.

Conclusion Overall, I am satisfied with my experience using Gluco Shield Pro. The product has provided me with several benefits, including improved energy levels, enhanced mental clarity, and potential support for healthy blood sugar management. If you are looking for a natural supplement to support your overall well-being, I would recommend giving Gluco Shield Pro a try.

Disclaimer It is important to note that individual results may vary. Gluco Shield Pro is not a substitute for medical advice or treatment. If you have any concerns about your health or blood sugar levels, it is crucial to consult with a healthcare professional.

[inclosedwalldelusion]

40 sentences that will teach you more about nutrition than a $400,000 medical degree

From Brett Boettcher @brettboettcher1

40 sentences that will teach you more about nutrition than a $400,000 medical degree.

1) Meat, eggs and animal organs are the most nutrient dense foods on the planet.

2) Bone broth is loaded in collagen and helps repair the gut so you can heal from the inside out.

3) Saturated fat doesn’t cause heart disease, insulin resistance does.

4) Your ratio of triglycerides to HDL is a great indicator of mortality risk; the lower the better. ·

5) Protein is the most metabolically active macronutrient and it isn’t bad for your kidneys.

6) There isn’t quality evidence to show that dietary cholesterol impacts the cholesterol in your blood. ·

7) There is even less evidence to support that total cholesterol is bad for your health since it is inversely correlated to mortality risk. · 4h 8) Walking before and after meals is a great way to improve digestion and reduce blood sugar spikes.

9) Fiber is the last thing you need if you have IBS or diverticulitis.

10) Dairy is great for your health and its saturated fat intake is inversely correlated to heart disease.

11) Most nutritional recommendations were introduced based on profit margins, not health outcomes.

12) Calories in and calories out is all that matter, but some calories make you hungrier (sugar/grains). Other calories (protein) help you burn more calories.

13) Multi grain just means they took 2+ different terrible sources of grain and put them together into one product.

14) Cereal and bread for breakfast will spike your blood sugar and have you starving before lunch. Try Greek yogurt or eggs instead. ·

15) “Intuitive eating” and “listen to your body” makes no sense considering 88% of people are metabolically unhealthy and addicted to food. No one would say “intuitive crack use.”

16) Eating is a stress on your body; The less often you can eat, the healthier you’ll be.

17) Plan your meals around the protein source (with its natural fat) and add a small side of carbs if needed.

18) Eating for satiety is more important than relying constantly on willpower. Find filling foods and avoid foods with addictive properties (ultra-processed).

19) You don’t have to know how to cook. Grill a meat, sauté a green vegetable, bake a potato. Mix and match a million ways.

20) Eating many of the same foods every week isn’t perfectly optimal but it’s likely your best path to consistency and therefore success. ·

21) Becoming more insulin sensitive should be the focus of any health-related nutrition plan.

22) Salad dressings are one of the worst things you can eat for your health. High in calories and inflammatory industrial oils.

23) Eating 5x per day won’t boost your metabolism. If you are trying to gain weight, it’s an excellent strategy.

24) Bacon can be healthy, just avoid the processing with nitrates.

25) Cottage cheese and Greek yogurt are two of the best sources of protein per calorie.

26) Carbs are beneficial around a workout. But many sources of carbs are processed and easily overeaten. Focus on single ingredient foods.

27) You can’t be healthy at any size no matter what your mother or liberal arts professor said.

28) Eat a high protein meal before attending social events that are filled with junk food.

29) If eating out, order the food with the highest protein content.

30) The #1 reason people fail is that they don’t prepare. Meal prep, meal plan, have ready to eat protein sources. · 31) The food you eat directly impacts your mental health and processed foods are correlated with depression and mental illness.

32) Processed foods have been engineered to be as addicting as possible. Your taste buds can be retrained with natural sources.

33) “Plant-based” foods are made in laboratories and are an easy way to sell overpriced junk to consumers at high margin.

34) Eating 1 gram of protein per lb of ideal body weight daily will do more for your body composition than spending 30 minutes on the treadmill.

35) When in doubt, if it comes from the center aisles of the grocery store or has more than 3 ingredients, it’s not good for you.

36) Many foods labeled as “keto” “paleo” or “high protein” are far from meeting the intended definition.

37) Your gut is responsible for 70% of your immune system; feeding it sugar and other inflammatory foods is making you sick now and later.

38) Genetics play a role but over 90% of the country has a resting metabolism within 500 calories daily. Being fit is possible for everyone.

39) Flipping the food pyramid upside down is closer to healthy eating than the traditional suggestions.

40) Eliminating drinking your calories is the first change to make when trying to improve your health.

[scientia-rex]

Because my most popular post is about weight loss and how it's a crock, I get a lot of questions about various things, including bariatric surgery--just posted the link to the post I did about that--but also Ozempic/Wegovy, the once-weekly injectable semaglutide medication that was developed for diabetes but was found to have independent benefits on weight loss.

I always said that weight loss was like Viagra: when a medication came along that actually worked, it would explode. We'd all hear about it. Fen-phen in the 90s worked, but it was bad for your heart. Stimulants, like meth, may cause weight loss, but they do it at the cost of heart health, and raise your likelihood of dying young. Over the counter weight loss supplements often contain illegal and unlisted thyroid hormone, which is also dangerous for the heart if taken in the absence of a real deficiency. Orlistat, or "Alli," works the same way as the Olestra chips Lays made in the 1990s--it shuts off your ability to digest fats, and the problem with that is that fats irritate the gut, so then you end up with fatty diarrhea and probably sharts. Plus Alli only leads to 8-10lbs of weight loss in the best case scenario, and most people are not willing to endure sharts for the sake of 8lbs.

And then came the GLP-1 agonists. GLP stands for glucagon-like peptide. Your body uses insulin to make cells uptake sugar. You can't just have free-floating sugar and use it, it has to go into the cells to be used. So if your body sucks at moving sugar into the cells, you end up with a bunch of glucose hanging out in places where it shouldn't be, depositing on small vessels, damaging nerves and your retinas and kidneys and everywhere else that has a whole lot of sensitive small blood vessels, like your brain.

Glucagon makes your liver break down stored sugars and release them. You can think of it as part of insulin's supporting cast. If your body needs sugar and you aren't eating it, you aren't going to die of hypoglycemia, unless you've got some rare genetic conditions--your liver is going to go, whoops, here you go! and cough it up.

But glucagon-like peptide doesn't act quite the same way. What glucagon-like peptide does is actually stimulating your body to release insulin. It inhibits glucagon secretion. It says, we're okay, we're full, we just ate, we don't need more glucagon right now.

This has been enough for many people to both improve blood sugar and cause weight loss. Some patients find they think about food less, which can be a blessing if you have an abnormally active hunger drive, or if you have or had an eating disorder.

However, every patient I've started on semaglutide in any form (Ozempic, Wegovy, or Rybelsus) has had nausea to start with, probably because it slows the rate of stomach emptying. And that nausea sometimes improves, and sometimes it doesn't. There's some reports out now of possible gastroparesis associated with it, which is where the stomach just stops contracting in a way that lets it empty normally into the small intestine. That may not sound like a big deal, but it's a lifelong ticket to abdominal pain and nausea and vomiting, and we are not good at treating it. We're talking Reglan, a sedating anti-nausea but pro-motility agent, which makes many of my patients too sleepy to function, or a gastric pacemaker, which is a relatively new surgery. You can also try a macrolide antibiotic, like erythromycin, but I have had almost no success in getting insurance to cover those and also they have their own significant side effects.

Rapid weight loss from any cause, whether illness, medication, or surgery, comes with problems. Your skin is not able to contract quickly. It probably will, over long periods of time, but "Ozempic face" and "Ozempic butt" are not what people who want to lose weight are looking for. Your vision of your ideal body does not include loose, excess skin.

The data are also pretty clear that you can't "kick start" weight loss with Ozempic and then maintain it with behavioral mechanisms. If you want to maintain the weight loss, you need to stay on the medication. A dose that is high enough to cause weight loss is significantly higher than the minimum dose where we see improvements in blood sugar, and with a higher dose comes higher risk of side effects.

I would wait on semaglutide. I would wait because it's been out for a couple of years now but with the current explosion in popularity we're going to see more nuanced data on side effects emerging. When you go from Phase III human trials to actual use in the world, you get thousands or millions more data points, and rare side effects that weren't seen in the small human trials become apparent. It's why I always say my favorite things for a drug to be are old, safe, and cheap.

I also suspect the oral form, Rybelsus, is going to get more popular and be refined in some way. It's currently prohibitively expensive--all of these are; we're talking 1200 or so bucks a month before insurance, and insurance coverage varies widely. I have patients who pay anything from zero to thirty to three hundred bucks a month for injectable semaglutide. I don't think I currently have anyone whose insurance covers Rybelsus who could also tolerate the nausea. My panel right now is about a thousand patients.

There are also other GLP-1 agonists. Victoza, a twice-daily injection, and Trulicity, and anything else that ends in "-aglutide". But those aren't as popular, despite being cheaper, and they aren't specifically approved for weight loss.

Mounjaro is a newer one, tirzepatide, that acts on two receptors rather than one. In addition to stimulating GLP-1 receptors, it also stimulates glucose-dependent insulinotropic polypeptide (GIP) receptors. It may work better; I'm not sure whether that's going to come with a concomitantly increased risk of side effects. It's still only approved for diabetes treatment, but I suspect that will change soon and I suspect we'll see a lot of cross-over in terms of using it to treat obesity.

I don't think these medications are going away. I also don't think they're right for everyone. They can reactivate medullary thyroid carcinoma; they can fuck up digestion; they may lead to decreased quality of life. So while there may be people who do well with them, it is okay if those people are not you. You do not owe being thin to anyone. You most certainly do not owe being thin to the extent that you should risk your health for it. Being thin makes navigating a deeply fat-hating world easier, in many ways, so I never blame anyone for wanting to be thin; I just want to emphasize that it is okay if you stay fat forever.