#Medical technology

[reasonsforhope]

"A team of researchers at Washington University in St. Louis has developed a real-time air monitor that can detect any of the SARS-CoV-2 virus variants that are present in a room in about 5 minutes.

The proof-of-concept device was created by researchers from the McKelvey School of Engineering and the School of Medicine at Washington University...

The results are contained in a July 10 publication in Nature Communications that provides details about how the technology works.

The device holds promise as a breakthrough that - when commercially available - could be used in hospitals and health care facilities, schools, congregate living quarters, and other public places to help detect not only the SARS-CoV-2 virus, but other respiratory virus aerosol such as influenza and respiratory syncytial virus (RSV) as well.

“There is nothing at the moment that tells us how safe a room is,” Cirrito said, in the university’s news release. “If you are in a room with 100 people, you don’t want to find out five days later whether you could be sick or not. The idea with this device is that you can know essentially in real time, or every 5 minutes, if there is a live virus in the air.”

How It Works

The team combined expertise in biosensing with knowhow in designing instruments that measure the toxicity of air. The resulting device is an air sampler that operates based on what’s called “wet cyclone technology.” Air is sucked into the sampler at very high speeds and is then mixed centrifugally with a fluid containing a nanobody that recognizes the spike protein from the SARS-CoV-2 virus. That fluid, which lines the walls of the sampler, creates a surface vortex that traps the virus aerosols. The wet cyclone sampler has a pump that collects the fluid and sends it to the biosensor for detection of the virus using electrochemistry.

The success of the instrument is linked to the extremely high velocity it generates - the monitor has a flow rate of about 1,000 liters per minute - allowing it to sample a much larger volume of air over a 5-minute collection period than what is possible with currently available commercial samplers. It’s also compact - about one foot wide and 10 inches tall - and lights up when a virus is detected, alerting users to increase airflow or circulation in the room.

Testing the Monitor

To test the monitor, the team placed it in the apartments of two Covid-positive patients. The real-time air samples from the bedrooms were then compared with air samples collected from a virus-free control room. The device detected the RNA of the virus in the air samples from the bedrooms but did not detect any in the control air samples.

In laboratory experiments that aerosolized SARS-CoV-2 into a room-sized chamber, the wet cyclone and biosensor were able to detect varying levels of airborne virus concentrations after only a few minutes of sampling, according to the study.

“We are starting with SARS-CoV-2, but there are plans to also measure influenza, RSV, rhinovirus and other top pathogens that routinely infect people,” Cirrito said. “In a hospital setting, the monitor could be used to measure for staph or strep, which cause all kinds of complications for patients. This could really have a major impact on people’s health.”

The Washington University team is now working to commercialize the air quality monitor."

-via Forbes, July 11, 2023

-

Holy shit. I know it's still early in the technology and more testing will inevitably be needed but holy shit.

Literally, if it bears out, this could revolutionize medicine. And maybe let immunocompromised people fucking go places again

Also, for those who don't know, Nature Communications is a very prestigious scientific journal that focuses on Pretty Big Deal research. Their review process is incredibly rigorous. This is an absolutely HUGE credibility boost to this research and prototype

[swtechspecs]

Zaltin Corporation Bacta Tank

Source: The Essential Guide to Weapons and Technology (Del Rey, 1997)

[reality-detective]

Clones are real then confirmed. Now the question is are we using this for good or evil?

Why are children dying waiting for transplants when this is possible and you know if it can be done, then they have already been doing it. 🤔

[materialsscienceandengineering]

Scientists transform blood into regenerative materials, paving the way for personalized, 3D-printed implants

Scientists have created a new 'biocooperative' material based on blood, which has been shown to successfully repair bones, paving the way for personalized regenerative blood products that could be used as effective therapies to treat injury and disease. Researchers from the Schools of Pharmacy and Chemical Engineering at the University of Nottingham have used peptide molecules that can guide key processes taking place during the natural healing of tissues to create living materials that enhance tissue regeneration. The research is published in Advanced Materials. Most of our body tissues have evolved to regenerate ruptures or fractures with remarkable efficacy, as long as these are small in size. This healing process is highly complex. The initial stages rely on liquid blood forming the solid regenerative hematoma (RH), a rich and living microenvironment comprising key cells, macromolecules, and factors that orchestrate regeneration.

Read more.

[heardatmedschool]

Medical Intern: Actually Medical Technology was my first choice when I graduated high school.

MT: Why? Did you think your grades were too low for medical school?

Intern: No, I was just scared of people.

what is a medical technologist?

[wikipediapictures]

Automated dispensing cabinet

“Pyxis SupplyStation automated dispensing cabinet at Campbell County Memorial Hospital in Gillette, Wyoming.” - via Wikimedia Commons

[troythecatfish]

[abybweisse]

Hey Aby ! I have a question (actually, two) for you regarding bizzare dolls that came into my mind just recently, maybe you’ve answered this question before so i apologize in advance.

Firstly, why do you think the Star Lords exist in the first place ? Like, sure, they “take care” of the blood collecting centers, but what else ? Do you think they have any purpose other than this ? Are they part of something greater ? Because as of now it seems to me they’re actually a waste of energies for Undertaker (like, you know, having to harvest blood for all of them, making sure they’re healthy and don’t lose control…)

Second and last question, why the different blood types ? I’ll explain this better, if Undertaker’s main goal is to keep R!Ciel ‘alive’ why not collecting just Sirius blood and calling it a day ?

I take this opportunity to thank you for being the literal pillar and backbone of our fandom 🫶🏻 who knows what we would be without you ! Lots of love !

⚠️ long post ⚠️

Ok, so I've sort of answered these questions before, but I'll try to be more specific and in depth about it here.

Why the Star Lords to begin with?

There are several parts to this answer, and I'll go into some more details about each one:

The star lords exist because Undertaker wants to bring back real Ciel

Even this part of the answer requires looking at a few different aspects. Real Ciel is one of the star lords, so wanting to bring him back automatically explains why he's one of them. Bringing in other individuals can serve some purposes. Such as:

So real Ciel isn't the only one; he's not alone. It gives him the added bonus of having (loyal) allies to go up against our earl and his allies (particularly Baldo, Mey-Rin, and Finny). These star lords can fight very well (though that might not be the case for real Ciel, since he's apparently only getting AB blood transfusions. More on that later. And he might naturally not be as physically inclined or well-trained). We pretty much have to assume, by now, that Polaris is the one who kills Agni. Real Ciel shooting at Soma (who mistook the shooter for our earl) and Polaris (mistaken for Sebastian, probably) killing Agni turned Soma into an enemy. Much of the star lords' existence seems to be about getting rid of our earl's support system.

The others might end up serving real Ciel in some other way, too, such as collecting blood supplies from the other facilities; we know Vega (Layla/Al) and Polaris are sent off by Undertaker to do that. At some point, real Ciel wants one of them to act as his butler, and later Polaris seems to be filling that role, even though he was away and unable to serve as one earlier. Either way, Polaris identifies as a butler "even in death".

So there's a representative for each major blood type (more on that in part two). That's about religion (or occultism), symbolism, and balance. It's also about scientific research.

The star lords exist because Undertaker wants to make a point to our earl about the choices he makes (which I find very ironic).

Choosing Doll (to represent Canopus) might have something to do with wanting to make our earl feel guilty for her death... if he ever sees her or finds out about her return. We won't know what/how he finds out until we get back to him and he's receiving reports. We aren't quite sure yet who Polaris is, but I suspect he's a former Phantomhive butler, and that could make our earl feel bad about his death, too, even though there was no way for him to prevent it. (Mostly, someone like a former Phantomhive butler for Polaris would be for the fierce loyalty that could be achieved with his "episodes".)

The star lords exist because Yana-san needs to provide more adversity.

Undertaker might also see Doll as someone who could take Snake away from our earl, because of their history. And even if Undertaker doesn't have that in mind, Yana-san sure does; it makes sense from a writer's perspective to have each of our earl's helpers deal with something that exposes their emotions and/or weaknesses. With Doll, Snake feels a sense of belonging, while Finny feels guilt. Layla/Al is good to go up against Lau and Baldo because they likely wouldn't suspect a little girl (by all appearances) to be much of a threat. Polaris is so strong, fast, and flexible that Mey-Rin and Ran-Mao have no idea how lucky they are that they were gone by the time Polaris found out what had happened. Agni and Soma weren't as lucky, dealing with Polaris and real Ciel. 😢

The star lords exist because backers of Aurora Society begged and/or paid to have dead loved ones revived.

At least that's what I think in the case of Layla/Al. I suspect she might be Baron Heathfield's dead daughter. Undertaker agreeing to help restore Heathfield's family might be why Heathfield got involved with Undertaker and the Aurora Society. Not just to find the right "soul shape" for his wife... but also to somehow revive his daughter.

The star lords exist because Undertaker is still curious about humanity (life, death, souls, etc.).

He's continuing to experiment. Even though the main purpose seems to be to revive real Ciel, the effects are much wider in scope. They really are one big series of experiments. Some elements of what he's been working on (possibly with a helper, like Druitt, on the medical aspects):

Manipulating cinematic records. He started out -- probably long before real Ciel was killed -- just adding little snippets of himself to their records, much like the BDs on the ship. He says that when he started working on real Ciel his revival techniques weren't up to snuff (not nonexistent, just not strong enough), so he needed to make quick progress. The others on the ship weren't for that purpose, so they don't really count here. The murders at Weston gave him an opportunity to improve upon record manipulation. And so do the other lords of the stars. This gives him more time to cherry pick which "episodes" to use for each one.

Blood typing and transfusion technology. It is way more advanced (than it should be at this time) because of his work... or the work of whoever is helping him in the lab. It's already led to the development of dialysis machines, too, which brings in another money-making opportunity. The star lords might not have functioning hearts, bone marrow, livers, or kidneys, so the blood transfusions are an ongoing need.

Organ transplants. Experimentation continues with organ transplants, since the orphanage staff mentions something about how hard it is to match the kids up with the star lords based on aptitude. With organ transplants, matching blood type isn't always enough. The personality test doesn't guarantee any more precision, of course, either, but that's not exactly the purpose of that test. Also, transplanted organs don't last forever, even in living humans, so they probably last even less time in a BD. As a star lord wears out their transfused blood, they probably also wear out transplanted organs and other tissues.

Soul transplants. We don't have absolute proof just yet, but I do think Undertaker is also experimenting with transplanting souls into the star lords. On the ship, he says BDs can't do anything with the souls of the people they attack. And he says he can't make souls. However, he hasn't said he can't manipulate souls that already exist; definitely, he has soul manipulation abilities that the BDs lack, and I think he's testing the limits of his own abilities. He's also got Heathfield thinking that he needs to find a woman with a soul the same "shape" as his dead wife's. As I said before, I think Undertaker might be using Heathfield's dead wife as a test subject for soul transplants. I do think he wants to transplant a similar or same-shaped soul into each of the star lords. Either Layla has Al due to one of these experiments... or Undertaker chose Layla to be one of the star lords partly because she already has Al, and Undertaker wants to study this dual personality. His reasoning might go that if he could just transplant the right soul into a star lord, then that star lord would be truly revived... would be able to pump and clean the blood that's been transfused... would be able to make more blood for themselves... would be able to make better use of the organs they've received.

The star lords exist because Undertaker needs a gimmick to lure in people to give blood (whether or not they know that blood is being taken) and for patrons to donate money.

And that's where the different blood types become even more important.

Why the different blood types?

I suppose Undertaker could focus all the efforts on just getting AB "Sirius" blood for real Ciel. But there are benefits to collecting all four types in the ABO blood grouping system (ignoring Rh factor).

AB is rare, and it would still require blood typing a large number of people to figure out who has AB. Hence why they opened Sphere Music Hall and made it a mixing space for all walks of life, placed ads for maids of all backgrounds for Heathfield, offered state of the art medical services for veterans at Athena Sanatorium. and provided a shelter and rare education opportunity for orphans at F. O. L. And people would feel unwelcome if most of them (or any of them, really) were turned away. Making the facilities as inclusive as possible (particularly the music hall and Heathfield's manor) increases the likelihood of getting enough AB blood for real Ciel.

And since Undertaker (and whoever) now also has all this blood for A, B, and O, he should do something with it. By then, probably anticipating the fact that he'd have blood supplies for different recipients, he'd have selected the other three star lords to match the remaining blood types. Each star lord just sort of falls into place, most likely. Real Ciel has AB. "Polaris" is A, so that works. This girl Layla is unusual, plus she's got type O; great, let's bring her on board. And Doll happens to be B; perfect, now all four types are covered.

In the case of Sphere Music Hall, there's also a major occult aspect to it, and having these four portray worshipped individuals works out well to lure people in and gives each visitor a purpose. Even the lesser "stars" that make up the multitudes are useful. Truth is, most of them didn't even know about the star lords; they were too caught up in adoration for the idol singers. Built-in idolatry. Layer upon layer to shroud the star lords in mystery.

For a while, there was so much extra A and O blood that they could also distribute it to renal failure patients who donated money to Aurora Society. Like those old guys in Bath.

There's also the fact that a major truth about the ABO blood grouping system has been, so far, either ignored or misunderstood within the story. When it comes to whole blood transfusions, AB is the universal recipient, so real Ciel doesn't have to "starve" from the scarcity of his blood type. All this time, he could have accepted any of them. It actually all could have been collected for him... from anyone (again, ignoring rh factor). All this trouble to collect AB blood for him could have been avoided, but either the researchers don't yet know this fact, or they know but still aren't making use of it. There is also the possibility that even real Ciel now knows this, but he's refusing anything but AB due to elitist bias. Keep in mind that they have created their own caste system within this "blue cult", despite saying how everyone is welcome and to be treated equally. There's obviously a premium put on Sirius and Canopus. And there've been a few times where individuals talked down to anyone who wasn't amongst the cult's elite and described the vast majority of participants as lesser or "dim" stars.

I'm still waiting for someone (maybe Sieglinde?) to point this out to Undertaker (and whoever is doing the bulk of the blood work). So, part of the reason to have a star lord for each blood type might be to lead up to the revelation that they went through a bunch of completely unnecessary lengths... and to maybe show them that -- for all the knowledge they had -- they still knew so little.

Well, I hope this sufficiently answers your questions. 😂 I feel like I'm forgetting something, but after typing this much, I can't think too clearly about what that might be. 😮‍💨 😅

And thank you so much!! 😊

[vizreef]

‘Lift your left or right hand accordingly‘

Beltone Audiometer Model 15C (US, 1960s)

[razzek]

Whenever people start getting excitted about tech companies putting things in their heads, I tell them about what Second Sight did to their Argus II patients.

[burikumu]

Sharing my "ideal" study schedule weeks before the MTLE March 2024 (Board Exam)

Of course this didn't happen/ there were some adjustments made 😅

Also I'm not sure what I was doing. I might go on a little bit of more detail about the schedule on the NEXT POST.

What I did basically:

SCHEDULING

I've allotted Sunday as my rest day and scheduled my breaks.

Each subject, supposedly covers 4 hours (but I miscalculated the other times of the day and only became about 3 hrs, hence the adjustments)

INTERLEAVING

Since I had a lot of subjects to cover I've tried to incorporate this method instead of blocking.

Videos that helped me in Scheduling and Interleaving:

How to study MANY SUBJECTS without crying from stress & regret 😭 by fayefilms

A Science based System for Learning ANYTHING quickly by Python Programmer

How to study multiple subjects by Koi Academy

Videos that help me to understand revision and other study methods:

Lecture #9: How to Read so that you *Retain* Information by Jeffrey Kaplan

Spend 1 Hour Studying to Save 20 Hrs Later by Justin Sung

Study With Me (Live) - Guided Technique Walkthrough by Justin Sung

How to Revise EFFICIENTLY | STUDY CLINIC by Justin Sung

The Ultimate Speed Learning Tutorial (Learning in Layers) by Koi Academy

How Do You Revise for an Exam? (Live Coaching | JUST-IN-CASE) by Justin Sung

[reasonsforhope]

"Thanks to a new discovery by researchers at the Massachusetts Institute of Technology, painful injections and intravenous drugs could potentially be a thing of the past.

Inspired by the way squids (yes, squids!) use jets to propel themselves through the ocean, shooting ink clouds, researchers took this biological process to the lab.

The result is an ingestible capsule that “releases a burst of drugs directly into the wall of the stomach or other organs in the digestive tract,” developed by researchers from MIT and Novo Nordisk...

Traverso was the senior author of the study, which concludes that the capsule could offer an alternative to delivering drugs that normally have to be injected, like insulin, antibodies, and even mRNA.

The reason these drugs cannot be taken orally is because they consist of large proteins that are easily broken down in the digestive tract, rendering them ineffective. 

For years, Traverso’s lab has been working on a solution, encapsulating these drugs in small devices that protect them through their journey in the body until they reach the lining of the digestive tract, where they can be injected directly into the system.

In previous iterations, he and his colleagues devised capsules that use microneedles to deliver the drugs once they enter the digestive system.

But in this new study (recently published in Nature), the researchers went completely needle-free.

Taking inspiration from cephalopods — or squids and octopuses — the researchers came up with two ways to mimic their siphon organ, which allows these animals to shoot jets of ink to distract predators...

And don’t fret — once the drugs are administered, the capsules (which are made of metal and plastic) simply pass through the digestive tract naturally.

Although researchers have only tested the device on animals so far, the trails have shown resounding success. In these tests, the capsule successfully delivered insulin, a drug similar to Ozempic, and a type of RNA that can be used in treating genetic disorders.

In this research, success was calculated by measuring the concentration of drugs in the animals’ bloodstream, which reached the same levels as drugs administered by injections. Plus, there was no tissue damage after the fact...

According to MIT, the researchers will now work to further develop the capsules, in hopes of testing them in humans.

Their ultimate vision is that the capsules could be used at home by patients who need to take insulin or other injected drugs frequently. The approach also eliminates the need to dispose of sharp needles, creating a safer — and more comfortable — experience for patients and providers alike."

-via GoodGoodGood, November 25, 2024

[swtechspecs]

Darth Vader's Chest Box (Life Systems Computer)

Source: Star Wars Technical Journal (Del Rey, 1995)

[thoughts-of-therese]

Slayed Biochemistry!

Hello there! Just slammed my biochemistry finals for this semester. And I've gotta say that it was a 7/10 for me being 10 as difficult. I was glad since we no longer did a departamental exam but I know for a fact that I would just get a fine score 🤣

So for tomorrow, I will be partaking on our histology and HIS finals! A little nervous on histology so I will be pulling an all nighter tonight! 😭 but I know that I can do this, all with fullpower and motivation.

[materialsscienceandengineering]

In a paper published this week in Chaos, by AIP Publishing, researchers from Sergio Arboleda University in Bogotá, Colombia, and the Georgia Institute of Technology in Atlanta used an electrophysiological computer model of the heart's electrical circuits to examine the effect of the applied voltage field in multiple fibrillation-defibrillation scenarios. They discovered far less energy is needed than is currently used in state-of-the-art defibrillation techniques. "The results were not at all what we expected. We learned the mechanism for ultra-low-energy defibrillation is not related to synchronization of the excitation waves like we thought, but is instead related to whether the waves manage to propagate across regions of the tissue which have not had the time to fully recover from a previous excitation," author Roman Grigoriev said. "Our focus was on finding the optimal variation in time of the applied electric field over an extended time interval. Since the length of the time interval is not known a priori, it was incremented until a defibrillating protocol was found."

Read more.

[heardatmedschool]

*In the CT room*

Medical Technologist: *handing out lead apron* Careful, it’s heavy.

Intern: Last week I was on orthopedic surgery, I think I can hadle it.