#it's the third one in four years time

[newkiqx]

one advantage of having mice is you'll always have perfect bait for wild mice on hand

a disadvantage is that you will often need that because wild mice will be tempted to enter your house quite often

but it's not all bad. You get to catch a mouse really fast (you have perfect bait). And you get to look at this cute little guy you caught before releasing them

[kings-highway]

not sure if the overlap of ppl who read my stories and the people who will get this joke even exists, but I am so convinced that Daichi is afflicted by the markiplier "im not a masochist i just want to see if my body can handle it" curse.

[thebirdandhersong]

lads it is mostly my fault (was sick, didn't tell healthcare until it was Dire, was sentenced to bed rest for the rest of my time at camp) that I literally can't say goodbye to these 100+ people I've come to love properly before I leave. I'm not permitted to participate in any singing, dancing, communal joy, any event that's remotely fun (that's nearly word for word what they said) here at camp. and I'm leaving EARLY, am still miserably sick, and have a four hour commute back home on top of that, because there's no one available to drive. literally cried my eyes out over everything just now and am This Close to crying my eyes out againnnnn

[fluffalpenguin]

the mean girls of duel academia

[idontliketomatoesleavemealone]

I think my mom doesn’t understand that people grow apart sometimes and that’s okay

[tipytap]

what am i supposed to do now. find another book to read???? wack

[peach-pot]

I love how the tumblr app becomes practically unusable when you have a post getting a lot of notes

[aparticularbandit]

Yui. Bestie. I love you. But Kyoko is literally twelve. And you are sixteen.

And like. I know the series are really, really trying to set them up as older sister/younger sister. And as Kyoko being a second attempt for Yui at protecting her own younger sister.

But then you get tiny descriptions like this and I just.

Yui. Bestie. I just.

I'm having a hard time grappling with the sisters dynamic I know is supposed to be here when you keep making comments about Kyoko's appearance and wanting to dress up to go out with her and how much you depend on her.

Twelve year old Kyoko? Definitely can have a crush on her oni-sama. Totally believable.

But Yui??

Meeeeeeeehhhhhhh.

[samarecharm]

Scheming…

[trans-cuchulainn]

okay i've finished rewatching pride now i will stop having feelings all over your dash

[continuousmeowing]

I have a 5 or 6 hour flight there are like 4 ways this is going to end. I am going to die.

[struggling-to-find-home]

Sometimes I remember the fact that one time during camp me & four other girls got sent to live in a cabin meant for 25+ people by ourselves and during the three weeks we spent there had the biggest amounts of horror experiences I've ever experienced in a single camp trip and I just think to myself, what the fuck

[seekerstone]

12.5k/25k nano camp words :) five whole days ahead of schedule too :) i love nano so much i wish it were all year round but with occasional breaks so i don’t explode and die

[daisyachain]

The question of when Hanai and Tajima will get together. I’ve seen it put that Hanai is a fairly normal well-mannered person and Tajime is open as a book, so there’s no earthly reason to engage in Abe and Mihashi’s struggle for proximity. I’ve also seen it said that their friendship is too much based on their inferiority complexes and that to meet on even terms they’d have to reboot their friendship and built it independent from the game.

I’d raise the third option of: Hanai’s sensible and Tajima’s empathetic. No way is Hanai going to go out with Tajima without a long term plan. It’s too important a friendship to squander on a few failed dates and it’s also too weird of a friendship to transition without some serious thought to what it’s going to look like being exposed to Tajima 7 days a week forever. No way would he ask him out or accept a date before second-year uni at the earliest. Now, Hanai is restrained in his signals and Tajima often reads him like a book despite that. Just as Hanai wouldn’t date him without serious commitment in mind, I wager that Tajima picks up on the we’ll-cross-that-bridge vibes and maintains a friendly level of flirt. He wouldn’t be too keen on being rejected.

[bluedestinybluebird]

I have 2020 autumn's flashbacks (except they're compiled into one (yester)day)

[reasonsforhope]

"The first modern attempt at transferring a uterus from one human to another occurred at the turn of the millennium. But surgeons had to remove the organ, which had become necrotic, 99 days later. The first successful transplant was performed in 2011 — but even then, the recipient wasn’t immediately able to get pregnant and deliver a baby. It took three more years for the first person in the world with a transplanted uterus to give birth. 

More than 70 such babies have been born globally in the decade since. “It’s a complete new world,” said Giuliano Testa, chief of abdominal transplant at Baylor University Medical Center.

Almost a third of those babies — 22 and counting — have been born in Dallas at Baylor. On Thursday, Testa and his team published a major cohort study in JAMA analyzing the results from the program’s first 20 patients. All women were of reproductive age and had no uterus (most having been born without one), but had at least one functioning ovary. Most of the uteri came from living donors, but two came from deceased donors.

Fourteen women had successful transplants, all of whom were able to have at least one baby.  

“That success rate is extraordinary, and I want that to get out there,” said Liza Johannesson, the medical director of uterus transplants at Baylor, who works with Testa and co-authored the study. “We want this to be an option for all women out there that need it.”

Six patients had transplant failures, all within two weeks of the procedure. Part of the problem may have been a learning curve: The study initially included only 10 patients, and five of the six with failed transplants were in that first group. These were “technical” failures, Testa said, involving aspects of the surgery such as how surgeons connected the organ’s blood vessels, what material was used for sutures, and selecting a uterus that would work well in a transplant. 

The team saw only one transplant fail in the second group of 10 people, the researchers said. All 20 transplants took place between September 2016 and August 2019.

Only one other cohort study has previously been published on uterus transplants, in 2022. A Swedish team, which included Johannesson before she moved to Baylor, performed seven successful transplants out of nine attempts. Six women, including the first transplant recipient to ever deliver a baby back in 2014, gave birth.

“It’s hard to extract data from that, because they were the first ones that did it,” Johannesson said. “This is the first time we can actually see the safety and efficacy of this procedure properly.”

So far, the signs are good: High success rates for transplants and live births, safe and healthy children so far, and early signs that immunosuppressants — typically given to transplant recipients so their bodies don’t reject the new organ — may not cause long-term harm, the researchers said. (The uterine transplants are removed after recipients no longer need them to deliver children.) And the Baylor team has figured out how to identify the right uterus for transfer: It should be from a donor who has had a baby before, is premenopausal, and, of course, who matches the blood type of the recipient, Testa said...

“They’ve really embraced the idea of practicing improvement as you go along, to understand how to make this safer or more effective. And that’s reflected in the results,” said Jessica Walter, an assistant professor of reproductive endocrinology and infertility at Northwestern University Feinberg School of Medicine, who co-authored an editorial on the research in JAMA...

Walter was a skeptic herself when she first learned about uterine transplants. The procedure seemed invasive and complicated. But she did her fellowship training at Penn Medicine, home to one of just four programs in the U.S. doing uterine transplants. 

“The firsts — the first time the patient received a transplant, the first time she got her period after the transplant, the positive pregnancy test,” Walter said. “Immersing myself in the science, the patients, the practitioners, and researchers — it really changed my opinion that this is science, and this is an innovation like anything else.” ...

Many transgender women are hopeful that uterine transplants might someday be available for them, but it’s likely a far-off possibility. Scientists need to rewind and do animal studies on how a uterus might fare in a different “hormonal milieu” before doing any clinical trials of the procedure with trans people, Wagner said.

Among cisgender women, more long-term research is still needed on the donors, recipients, and the children they have, experts said.

“We want other centers to start up,” Johannesson said. “Our main goal is to publish all of our data, as much as we can.”"

-via Stat, August 16, 2024