#EXOGENOUS

[losprimeros]

altima down presents document in conjunction with neurotek sound | free party los angeles | 16th december 2023

[whats-in-a-sentence]

Such excised sections often respond to exogenous auxin by rapidly increasing their growth rate back to the level in the intact plant (Figure 18.12). (...) Thus, the outer tissues must be limiting the extension rate of the stem in absence of auxin (see Figure 18.12).

"Plant Physiology and Development" int'l 6e - Taiz, L., Zeiger, E., Møller, I.M., Murphy, A.

[conza]

Reality: Endogenous vs exogenous theory as to origin of the state. Endogenous is natural elite unfortunately "insisted against the opposition of other members of the social elite, that all conflicts within a specified territory be brought before him..."

— Hoppe

[tenth-sentence]

The application of exogenous gibberellin causes downregulation of the GA20ox and GA3ox genes, whose products catalyze the two final two steps in the formation of bioactive gibberellins (GA1 and GA4).

"Plant Physiology and Development" int'l 6e - Taiz, L., Zeiger, E., Møller, I.M., Murphy, A.

[arbitersart]

you're my best friend, i'll love you 'till one of us dies.

[tanadrin]

It’s nigh impossible to get through to people who have gen anxiety and depression for whatever reason. I try every day and fail, you just can’t win if a person hasn’t experienced cognition free of depression and reality testing and analysis free of anxiety. And if they are neurotic on top of it all, any advice or instruction will be taken as an insult and victimhood mentality will be reinforced. I say this with the utmost sympathy, it’s a really fucked up state to be trapped in.

It is! I’ve been in it. I’ve had people very close to me in it. It’s brutal. And if you are smart, rational, thoughtful, and this is a new development, it’s worse, because the idea that the systems with which you synthesize attitudes about the world are miscalibrated or stuck in some kind of pessimistic attractor state due to inputs that have nothing to do with the thing you are fixating on as the problem, is one that just seems inherently implausible. Insulting, even.

But that’s just how the human brain works. Our emotions, which we rely on for all kinds of judgements for cognitively kludgey reasons, can be affected by things that seem to not be related, like how much exercise we got today, or the last time we hung out with friends being too long ago, or not enough sunshine.

But even if we are smart and rational and thoughtful, we are also highly social savannah runners who need to do highly social savannah runner things to be happy.

[microsoftoutlook]

smiling peacefully

[samwiselastname]

why is hysto is the default surgery for ftms anyway. pap smears are fine. I'm going to be seeing a gynecologist for the rest of my life anyway. your uterus is literally uninvolved in the endocrine system. the uterus doesn't cause periods. oophorectomy removes your ability to get pregnant, stops periods, has even lower complication rates, and a much quicker recovery time. no one said the word 'ovary' to me until I brought it up and when I did bring it up, the psych writing my insurance letter was like "fight for that if you want it." like hello? there's not much gender in the uterus really!

[senselessalchemist]

finally have an actual job so maybe I can stop being a hermit and get officially divorced and feel sort of financially stable and possibly try dating again and get a cat ??? is that allowed? no I probably shouldn't unless I get a bigger place and can have two cats to be friends

downside is when the fuck am I supposed to draw dumb comics if I'm working for hours and hours a day? Hell and suffering on earth. maybe i should get an iPad or a whatthefuck ever and draw on the commute so I don't lose even more of my meager art skills

[riotingrogue]

I am an exogenic singlet.

explanation!!

I am a system. My system is traumagenic, I experienced the whole 9 yards as a kid, I have DID. But I really only associate my DID with my traumatic experiences, I don't really identify with system hood for my day to day life, and I'd rather be a singlet on a lot of days. So I coined exogenic to describe the origin of my singularity. I wasn't born a singlet and I didn't integrate, I just decided to be one because it's easier. Sometimes I'll call myself a system if it's relevant but honestly I really just prefer being an exogenic singlet

[religion-is-a-mental-illness]

By: Michael Searles

Published: May 26, 2024

Transgender men are suffering from “postmenopausal” problems like incontinence in their 20s because of taking testosterone, a study has revealed.

Experts analysed 68 transgender men who were taking the cross-sex hormone to change their identity from female to male and found that 95 per cent had developed pelvic floor dysfunction.

The participants, who were as young as 18 and had an average age of 28, had bladder and bowel symptoms that medics would expect to see in a woman after the menopause.

Experts said the impact of the sex-changing drugs on bodily functions are under-researched and under-reported, with people “not being informed of the risks at gender clinics”.

Around 87 per cent of the participants had urinary symptoms such as incontinence, frequent toilet visits and bed-wetting, while 74 per cent had bowel issues including constipation or being unable to hold stools or wind in. Some 53 per cent suffered from sexual dysfunction.

The researchers said the rate of urinary incontinence, where urine unintentionally leaks, was around three times higher in transgender men than women, affecting around one in four compared to eight per cent of the general female population.

Other trans men suffered from frequent urinating including during the night, burning sensations, hesitancy, urgency and difficulty in going, while others had issues defecating.

Almost half had an “orgasm disorder”, while a quarter suffered from pain during sexual intercourse.

Experts warned that the drugs were putting young people on “exactly the same trajectory” as those going through the menopause. A third of the participants in the study were students.

Elaine Miller, a pelvic health physiotherapist and member of the Chartered Society of Physiotherapy, said: “A lot of women are absolutely fine until the menopause and then they start to get leaky. That appears to be exactly the same trajectory for female people who take cross-sex hormones, but there hasn’t been much in the way of research.”

She said she had worked with around 20 detransitioners who sought help for pelvic floor issues - and many more from around the world had been in touch - but that there was a “stigma” around incontinence and that people were “embarrassed” and minimised the issue.

“Wetting yourself is something that just is not socially acceptable, and it stops people from exercising, it stops them from having intimate relationships, it stops them from travelling, it has work impacts,” she said.

“The impact a bit of leaking has on these young people’s lives is huge. It really needs to be properly discussed within gender clinics because I would expect that almost 100 per cent of female people that take cross-sex hormones will end up with these problems,” she added, noting that the study was “robust” and probably underplayed the issue.

“It’s really sad when we hear people say, ‘nobody ever told me this’, and they should have been informed of the risks in gender clinics.”

The menopause causes a loss of muscle mass and body strength, which affects the pelvic floor and can cause incontinence.

Women who start the menopause early or prematurely, under the age of 45, should be offered Hormone Replacement Therapy (HRT) on the NHS because the oestrogen can help prevent the onset of conditions such as coronary heart disease, osteoporosis and dementia.

Taking testosterone may accelerate the menopausal process because it stops the ovaries from functioning and reduces the amount of oestrogen the body produces.

Testosterone is also known to affect muscle mass and hair loss, and has been linked to blood clots and gallstones, but there has been little research into pelvic floor issues and incontinence.

Ms Miller said the treatment for trans men was “the same as with any other postmenopausal female, which seems kind of ludicrous when you’re talking about people that are in their early 20s”.

“It’s making sure they are not constipated, getting them into a routine where they are not dehydrating themselves because they’re worried about having an accident. A lot of it is about bladder and bowel education about what is normal, and doing pelvic floor exercises, which can make a big difference,” she added.

Kate Barker, chief executive at the LGB Alliance, said the group had “consistently spoken out about the damage done by these experimental surgeries, the overwhelming majority of which are carried out on LGB [lesbian, gay and bisexual] people”.

“Our annual conference has heard testimony from detransitioners who live every day with the consequences of actions they took when they were very young - sometimes in their teens - including permanent sterilisation and loss of sexual function,” she said. “This has finally been officially confirmed by the Cass Review.”

The Cass Review saw the NHS stop prescribing puberty blockers outside of clinical trials and a pause to cross-sex hormones being given to under 18s. It called for more care to be given in the treatment of under 25s and the health service is reviewing adult clinics as a result.

The authors of the study, led by Lyvia Maria Bezerra da Silva at the Federal University of Pernambuco, Brazil, said the findings “showed a high frequency of at least one of the pelvic floor dysfunction symptoms” and that more research into the impact of testosterone was needed because the “long-term effects are still unknown”.

The research was published in the International Urogynecology Journal.

[ Via: https://archive.today/wNl3q ]

--

Abstract

Introduction and Hypothesis

The objective of this research is to explore the effects of hormone therapy using testosterone on pelvic floor dysfunction (PFD) in transgender men. We hypothesize that PFD might be prevalent among transgender men undergoing hormone therapy. Therefore, this study was aimed at verifying the frequency of these dysfunctions.

Methods

A cross-sectional study was conducted between September 2022 and March 2023 using an online questionnaire, which included transgender men over 18 years old who underwent gender-affirming hormone therapy. Volunteers with neurological disease, previous urogynecology surgery, active urinary tract infection, and individuals without access to the internet were excluded. The questionnaire employed validated tools to assess urinary symptoms, such as urinary incontinence (UI), as well as sexual dysfunction, anorectal symptoms, and constipation. The data were analyzed descriptively and presented as frequencies and prevalence ratios with their respective confidence intervals (95% CI), mean, and standard deviation.

Results

A total of 68 transgender men were included. Most participants had storage symptoms (69.1%), sexual dysfunction (52.9%), anorectal symptoms (45.6%), and flatal incontinence (39.7%). Participants with UI symptoms reported moderate severity of the condition.

Conclusions

Transgender men on hormone therapy have a high incidence of PFD (94.1%) and experience a greater occurrence of urinary symptoms (86.7%).

[losprimeros]

altima down presents document in conjunction with neurotek sound | free party los angeles | 16th december 2023

[stigmasochist]

.

[chicago-geniza]

On the other hand I've had maybe one migraine a month since we raised my T dose and I've been having daily to weekly-at-absolute-minimum migraines since I was five or six years old. It's fucking insane that hormones can do that

[noinou]

TAKE ESTROGEN TAKE ESTROGEN TAKE ESTROGEN BABE IM SO SORRY BUT U NEED TO GET ON E

[arbitersart]

i really oopsied taking on too much responsibility, huh