#pediatric brain cancer

[l1v3r-al0n3]

Big news.

I never planned to be open about this here, but I just got the biggest news of my life and I just need to share.

I was diagnosed with stage 2 brain cancer when I was eleven years old. I started rapidly going blind and was in chemotherapy until I turned 13. They stopped treating me after my right eye completely lost vision because they couldn't do anything else for me. When I finally got out of chemotherapy I had to get MRI's every 3 months for four years an until they switched to annually. I was told that it could and likely would come back and that it may become terminal.

Today I met with my specialists and they told me I was officially in remission. I don't have any more appointments, no MRI's, no more blood work, no more tests, and no more surgeries. I lost almost eight years of my life to cancer and now I'm finally getting to take them back. I'm officially a survivor. At 18 years old.

I officially beat cancer.

To the two of my exes who told me they hoped my cancer came back and wished death on me? Fuck you. Fuck you for everything. I beat cancers ass and there's nothing you can do about it. You can't take that away from me.

[medicomunicare]

EneMyc more than ever: kids' cancer has priority for precision medicine

Brain tumors are the leading cause of childhood cancer deaths, and medulloblastoma is the most common type of brain tumor in children. It affects approximately 500 children each year in Canada and the United States, making improved diagnosis and treatment a top priority in pediatric oncology. While some children with medulloblastoma respond well to treatment, others have aggressive tumors that…

[supernerdninja]

I Can Attest To The Fact That Brain Tumors Suck, Which Is Why I Go Hard For The Environment

More children die from brain tumors than any other cancer; those who survive must navigate a lifetime of side effects. The Pediatric Brain Tumor Foundation (www.curethekids.org/stay-connected) is the largest patient advocacy funder of pediatric brain tumor research and leading champion for families and survivors, providing patients, caregivers, and siblings with information, financial assistance,…

[mrcrawly]

MORE house MD headcanons (just hilson)

finished season 2 officially FINALLY. took forever. anyway these freaks live in the little furrows of my brain and eat my grey matter so here's this

House:

had multiple deadly allergies as a kid that he grew out of as an adult for some reason

the pickiest eater you have ever seen. the canned soup is not a laziness thing he's just afraid to waste his money on shit he won't eat

composes his own songs on the piano when he's got time but never writes then down, freestyles that shit

DEFINITELY has some pot he smokes a few times a year

obviously when Wilson learns this he's concerned that maybe it's laced and is like House where are you getting this and House literally tells him the exact location on the exact part of town on the exact street and where the guy normally is on weekdays because he assumes Wilson wanted in on it

subconsciously thinks of Chase, Cameron, and Foreman as his children. of course he doesn't realize it nor would he ever admit it so don't misinterpret but lwk worries about them a lot and talks about them to acquaintances in such a way that multiple people actually think he has three grown up children

gets overstimulated fairly easily but not the shut-down-get-quiet overstimulation he starts yelling and hitting things and getting pissed off

has bad anxiety but in the opposite way most people do. doesn't get anxious in most social situations at all whatsoever but give that man ten minutes alone with his thoughts in his own house and he's sweating

doesn't sing but has perfect pitch. sometimes someone in the office will hum something or make a noise and he'll just absently go "E flat" (based on one of my irl friends noah you won't see this but you freak me the fuck out with that)

runs cold all year (something something universal recipient)

eventually stops drinking because it gives him panic attacks and nightmares

sad weepy drunk

pretends not to care about patients but there have been several times that a patient died and made him completely shut down for days at a time

views his disability as something to compensate for

if House MD took place in the modern day he would definitely have a twitch live stream about a patient to get idea

chronic nail biter

most definitely would own one of those massive fucking brick flip phones even if the show was set today

he doesn't know what OS stands for. couldn't tell you what a USB-C looked like if his life depended on it. wouldn't be very good at operating a smart phone. has an extremely durable cheap phone because he's always dropping and/or throwing it

Wilson:

lactose intolerant methinks

or possibly gluten sensitive

would still eat gluten bread and dairy products regardless

never quite got the hang of chopsticks. if he gets sushi or Chinese takeout with House, House makes that little chopsticks contraption for him

do you guys know what im talking about

the kind of autism that makes you feel bad about everything ever all the time and obsessed with a particular thing

definitely collected baseball cards at some point in his life

doesn't really keep kosher but hates most meat so he rarely ends up mixing dairy and meat anyways

if you gave him one of those Nee Doh nice cube things he would sit there and play with that shit for hours at a time

if he was born in the right generation he would have loved slime as a kid

ended up really close with House's team

does marching Halloween costumes with House every single year

House actually doesn't like Halloween (lots of walking) but it makes Wilson happy so usually he agrees

one year they went as American Gothic (House insisted on being the old man with the pitchfork and now everyone has photos of Wilson in a bad blonde wig)

really good in pediatrics. it really wears on him if he has a young patient but he handles it really well

taught himself to make balloon animals for the pediatric cancer patients

runs warm all year (something something universal donor)

big spoon

has joint problems but he insists it's not that bad so he won't go get seen for it

favorite movie is Pretty in Pink

office teddy bear. working in oncology is hard and some of the nurses just don't take it as well, so if he's around he takes it upon himself to comfort them

shockingly pretty good with technology and phones. i like to think this is because he has a fairly adaptive personality as it is and medical technology (especially in oncology) is always changing so he's used to keeping up with new things

definitely would have one of those fucking military ass otterboxes and a tempered glass screen protector and a camera protector like someone is gonna come run over his fucking phone

lwk i think he'd be kinky asf but im gonna leave that there

[reasonsforhope]

"In a first-ever human clinical trial, an mRNA cancer vaccine developed at the University of Florida successfully reprogrammed patients’ immune systems to fiercely attack glioblastoma, the most aggressive and lethal brain tumor.

The results in four adult patients mirrored those in 10 pet dog patients suffering from brain tumors whose owners approved of their participation.

The discovery represents a potential new way to recruit the immune system to fight treatment-resistant cancers using an iteration of mRNA technology and lipid nanoparticles, similar to COVID-19 vaccines, but with two key differences: use of a patient’s own tumor cells to create a personalized vaccine, and a newly engineered complex delivery mechanism within the vaccine.

“Instead of us injecting single particles, we’re injecting clusters of particles that are wrapping around each other like onions,” said senior author Elias Sayour, M.D., Ph.D., a UF Health pediatric oncologist who pioneered the new vaccine, which like other immunotherapies attempts to “educate” the immune system that a tumor is foreign.

“These clusters alert the immune system in a much more profound way than single particles would.”

Among the most impressive findings was how quickly the new method spurred a vigorous immune-system response to reject the tumor, said Sayour, principal investigator at the University’s RNA Engineering Laboratory and McKnight Brain Institute investigator who led the multi-institution research team.

“In less than 48 hours, we could see these tumors shifting from what we refer to as ‘cold’—very few immune cells, very silenced immune response—to ‘hot,’ very active immune response,” he said.

“That was very surprising given how quick this happened, and what that told us is we were able to activate the early part of the immune system very rapidly against these cancers, and that’s critical to unlock the later effects of the immune response,” he explained in a video (below).

Glioblastoma is among the most devastating diagnoses, with median survival around 15 months. Current standard of care involves surgery, radiation and some combination of chemotherapy.

The new report, published May 1 in the journal Cell, is the culmination of seven years of promising studies, starting in preclinical mouse models.

In the cohort of four patients, genetic material called RNA was extracted from each patient’s own surgically removed tumor, and then messenger RNA (mRNA)—the blueprint of what is inside every cell, including tumor cells—was amplified and wrapped in the newly designed high-tech packaging of biocompatible lipid nanoparticles, to make tumor cells “look” like a dangerous virus when reinjected into the bloodstream to prompt an immune-system response.

The vaccine was personalized to each patient with a goal of getting the most out of their unique immune system...

While too early in the trial to assess the clinical effects of the vaccine, the patients either lived disease-free longer than expected or survived longer than expected. The 10 pet dogs lived a median of 4.5 months, compared with a median survival of 30-60 days typical for dogs with the condition.

The next step, with support from the Food and Drug Administration and the CureSearch for Children’s Cancer foundation, will be an expanded Phase I clinical trial to include up to 24 adult and pediatric patients to validate the findings. Once an optimal and safe dose is confirmed, an estimated 25 children would participate in Phase 2."

-via Good News Network, May 11, 2024

-video via University of Florida Health, May 1, 2024

[religion-is-a-mental-illness]

We have a serious problem

Michael Laidlaw, MD: I'm a board-certified endocrinologist, practicing in private practice for the last 16 years. I've been studying and publishing in this area for the last 5 years, including peer reviewed journals such as Journal of of Clinical Endocrinology and Metabolism, and others. I also have a patient who is a detransitioner.

I think it's important to note that studies are shown that desistance, or growing out of this condition, of children by adulthood is very high. It's some 50-98%.

I want to be sure before I give someone a very powerful hormone like Insulin that they in fact have diabetes.

What about cancer? Before we give any powerful agents such as chemotherapeutics or surgeries, we certainly want to have physical evidence of this problem, such as biopsies or imaging.

Now, the gender affirmative therapy treatment proposed by WPATH gives very powerful hormones and surgeries on what basis? Where can we find the gender identity to be certain that these children will not desist by adulthood? Can we use imaging of the brain or blood tests, genetic testing, are there other biomarkers to ensure that we are correct? There is no such thing.

Julia Mason, MD: The Endocrine Society put out guidelines in 2017, and they were very careful in the guidelines. One, to point out that the evidence was of low and very low quality. And they also said in the guidelines that they have no idea how you identify which kids are trans and require this treatment.

And then the American Academy of Pediatrics the next year just leapt into that void and said, oh, oh, we'll tell you how you know which kids. You ask them.

Prior to 2018 I had maybe one trans patient. But then there was another one. And another one. And another one.

It wasn't until later that I started asking questions like, wait, every single kid I send to the gender clinic gets put on puberty blockers or cross-sex hormones. Just, it was happening immediately.

Patrick Hunter, MD: This affirmative model of care has spread wildly in the last 8 years. Now we have objective, unbiased systematic reviews. These systematic reviews tell us the evidence for youth transition is poor quality, and with very low certainty for benefit.

In JAMA Pediatrics, there was a study reported from Northwestern University in Chicago. Patients ranged in age from 13 to 24 years. The authors concluded that mastectomy was beneficial and should not be delayed in youth. What lead them to that conclusion? The finding that 3 months after surgery, the 36 patients were happy with their flat chests. They lost 9% of their surgical cases to follow-up. Nine percent. In 3 months.

It is absurd, meaningless to draw any conclusions after 3 months.

This paper is indicative of the quality of research we have in this field, published in our most prestigious journals.

We have a serious problem.

[afeelgoodblog]

The Best News of Last Week - June 13, 2023

1. U.S. judge blocks Florida ban on care for trans minors in narrow ruling, says ‘gender identity is real’

A federal judge temporarily blocked portions of a new Florida law that bans transgender minors from receiving puberty blockers, ruling Tuesday that the state has no rational basis for denying patients treatment.

Transgender medical treatment for minors is increasingly under attack in many states and has been subject to restrictions or outright bans. But it has been available in the United States for more than a decade and is endorsed by major medical associations.

2. Eagle Who Thought Rock Was an Egg Finally Gets to Be a Dad

A week after their introduction the cage where the little eaglet was put, was removed so the two could interact more closely. When they were given food, a whole fish for Murphy and bite-sized pieces for his young charge, rather than each eating their separate dish, Murphy took his portion and ripped it up to feed to the baby.

3. Little penguins to reclaim Tasmanian car park as city-based population thrives

Not far from the centre of Tasmania's fourth largest city, a colony of the world's smallest penguins has been thriving, and their habitat is about to expand into an existing car park.

The bright lights and loud noises of Burnie have not been a deterrent for hundreds of penguins who set up home on the foreshore in the north-west Tasmanian city.

4. Latest population survey yields good news for endangered vaquita porpoise

The resilient little vaquita marina appears determined to survive the illegal fishing that has brought it dangerously close to extinction, according to the latest population survey. Despite an estimated annual decline of 45% in 2018, the endangered porpoise appears to be holding steady over the last five years, according to a report published Wednesday by the International Union for Conservation of Nature.

5. 'Extinct' butterfly species reappears in UK

The species, previously described as extinct in Britain for nearly 100 years, has suddenly appeared in countryside on the edge of London. Small numbers of black-veined whites have been spotted flying in fields and hedgerows in south-east London. First listed as a British species during the reign of King Charles II, they officially became extinct in Britain in 1925.

This month they have mysteriously appeared among their favourite habitat: hawthorn and blackthorn trees on the edge of London, where I and other naturalists watched them flitting between hedgerows.

6. Colombian is a hero in Peru: he rescued 25 puppies that were about to die in a fire

During a structural fire that occurred in a residential area of ​​Lima in Peru, a young Colombian became a hero. The Colombian, identified as Sebastián Arias, climbed onto the roof where the puppies were and threw them towards the community, that was waiting for them with sheets and mattresses. "I love them, dogs fascinate me," said the young man.

7. World-first trial for pediatric brain cancer

Researchers in Australia are conducting a world-first clinical trial for children diagnosed with ependymoma, a rare and devastating brain cancer. The trial aims to test a new drug called Deflexifol, which combines chemotherapy drugs 5-FU and leucovorin, offering potentially less toxic and more effective treatment compared to current options.

Ependymoma is the third most common brain tumor in children, and current treatments often lead to relapses, with a high fatality rate for those affected. The trial, led by researcher David Ziegler at the Kids Cancer Centre, has received support from the Kids with Cancer Foundation and the Cancer Institute NSW. The goal is to find a cure for every child diagnosed with ependymoma.

----

That's it for this week :)

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[tragicallyuncreative]

Chapter five soon queen? Hope all is well!

Consider this my T-minus 12 hours or sooner announcement!!! I WILL be posting Chapter 5 tonight. Whether it be before or after midnight, I can't tell you, but I have tomorrow off and nothing due in the next 24 hours so I'm determined not to sleep before it's posted.

Thank y'all SO much for being so patient. All is well, just been so insanely busy that I haven't had a time to breath, let alone finish editing the chapter. I have learned so much in the last few weeks during my ICU rotations. Spent today managing hemorrhagic shock in a GI bleed patient (original bleed had been repaired and was about to be discharged when it was suddenly like a massacre 😬) and we gave 2 units of blood over the span of 1 minutes through a line in his internal jugular, then watched as they did a bedside emergent colonoscopy and put in 2 endoclips. Coolest shit I've seen in a while (well, not for him, poor guy). @fangirl-docintraining have you had your ICU rotations yet? As my fellow medical nerd who gets so excited/ enthusiastic about new stuff, you will love it!

The biggest reason this chapter has taken so long is my balance between keeping it completely accurate to 1960s medicine vs. incorporating modern elements in a realistic way because it's just hard not to and I really want to keep my plot/ outline intact. If anyone wants clarification about what elements are modern or not that I don't specify in my chapter notes, don't hesitate to ask. There are two articles that I would really love everyone to read before or after reading my chapter. For years, I have been so passionate about St. Jude Hospital and several specific doctors and the work they did/ continue to do to treat pediatric cancer. Dr. Emil Freireich essentially eliminated bleeding as a cause of death in leukemia patients after experimenting with his own platelets and finding the correct way to infuse them. He then proposed that the method of treating tuberculosis (using multiple drugs at once) could also cure leukemia. In 1962, pediatric leukemia was a death sentence. People thought it was crazy that Danny Thomas and these doctors were stating that they would find a way to cure it. Kids diagnosed would die within weeks of diagnosis from infection or bleeding to death. Their experimental treatment of combining two or more chemotherapeutic agents was seen as inhumane by many doctors, who thought that would make these children sicker and it was better to let them die peacefully. To everyone's shock, they saw success. This treatment was trialed in the early 60s, but didn't become something doctors would refer patients to St. Jude to until 1968ish. In 1970, the man behind this extraordinary discovery, Dr. Don Pinkel, was able to officially proclaim that childhood leukemia was no longer a fatal disease, with the cure rate at 50%. Today, ALL has a 94% cure rate, but the treatment remains harsh and lasts approximately 2.5 years. And despite all the hard work of researchers, other pediatric cancers such as Wilm's tumor, Ewing's sarcoma, osteosarcoma, rhabdomyosarcoma, medulloblastoma, DIPG, and more have high relapse rates and higher fatality rates (DIPG is something I encourage everyone to research and support higher funding for- a pediatric brain cancer with 0% survival rate). I actually went to a conference at St. Jude when I was 19 for childhood cancer advocates as I was a top fundraiser that year and interested in a future career there. I cannot say enough positive things about it!

So obviously, my story will deviate the timeline a little and the fictional Children's Hospital of Oklahoma (which in reality was not established until the 21st century) will be offering this experimental treatment in '65. Some of the medications and medical devices I include were not available until after '65 (for example, ports/ central lines in this particular model were not a thing), but I also make a point to use meds that were more common during the time, not include certain devices such as heart monitors, pulse ox, etc.

This has turned into a really long ramble. The point is, I hope everyone is ready to learn a lot this chapter and I encourage you to let this motivate you to learn more about childhood cancer, the fact that it is not as rare as many think, and that it is severely underfunded.

So far, this chapter is 15K words. My last few hours of edits may result in more or a little less. So get comfy and settle in when it's time to read- it's a big one with a lot going on!!

[revscarecrow]

Translation of post:

I was bullshitting when I said I knew what the charity streams were this year. I thought that since one was done for Ukraine, one would possibly for done for Palestine or Israel (I don’t support Israel, I’m just insinuating your friends would). Everyone would most likely have a bad take, because they aren’t as political as you, possibly even being zionists. The pediatric cancer research fund and the Palestine children’s relief fund have the same acronym. Therefore, if they announced the charity stream for the cancer fund with the acronym, everyone would assume it would be for Palestine. I want you to stop being friends with the vinesauce circle, because they probably don’t have very good politics. The only other vinesauce related person to have ever done anything with Palestine stuff (to my knowledge) was Gpm, and that time it was apparently an accident. I’m not expecting a charity stream for Palestine, nor am I expecting any of them to speak about it, because I feel like they would all have bad takes. You do not need to tell them to do anything. But I generally feel like you shouldn’t be friends with any of them, because I feel they’re not leftist enough. Besides, from what I remember, Joel set up the Ukraine thing (I might be extremely wrong) and since he is from europe, he probably did it because he felt threatened by russia.

tldr: I think your friends are probably zionists. Tbh, until they show otherwise, I believe that most content creators/Jewish people are.

Alright I gave this another go this morning and I'll give you a hot tip. This shit does make more sense when sober. Evil until proven otherwise is an wild purity test. Assuming all Jewish people support Isreal is also a hell of a take. Not being friends with people because they don't do thier job just like me is also a fucked up take. It's a really really bad move financially to talk the way I do. 1. Because gamers are only political when it regards titty censorship or the occasional shitty boycott (until the next big announcement happens). 2. It also pisses people off who agree with me because they might know I'm right and have been dealing with it and fighting the good fight and now when they come home to relax I'm also talking about it as well. Sometimes people just want to turn off their brains and for good reason. Activist burn out is real. So this thing I do is a really bad idea in general but I'm the type of person who can't shut up so I do it anyway. That doesn't mean that everyone has the same view point on how to do this streaming YouTube thing. It just means that's how I do it. Watch who you want for whatever reason you want but don't tell me who to be friends with or how to do my job and expect me to follow your directives.

[darkmaga-returns]

Story at-a-glance

Nebraska study reveals a 10% increase in pesticide exposure is linked to 36% rise in childhood brain cancers, 23% increase in leukemia, and 30% overall increase in pediatric cancers

Research analyzing 2,512 cancer cases over 22 years identified herbicides dicamba, glyphosate, and paraquat as significant contributors to childhood cancer development in agricultural regions

Children face heightened vulnerability to pesticide exposure through air, water, and soil due to developing organs and frequent hand-to-mouth contact during play

The research demonstrates the importance of examining combined effects of multiple pesticides rather than individual chemicals, to represent real-world agricultural exposure more accurately

Future research recommendations include human biomonitoring studies measuring pesticide levels in children's blood, plasma, and urine to better understand health impacts

[matthew-petracca]

Name: Matthew "Matt" Petracca

GENDER & PRONOUNS: Cis male, He/Him

AGE & BIRTHDAY: 34, December 19

OCCUPATION: Pediatric surgical resident

RESIDENCE: The Loft District, Skyline Lofts 

THREE POSITIVE TRAITS: Outgoing, funny, intelligent

THREE NEGATIVE TRAITS: immature, absent minded, unreliable 

Biography: tw: divorce, cancer

Matt grew up in Florida with his younger sister. He has a pretty normal childhood. He was close with his sister, who he was always over protective of. His mom was a dental hygienist and his father worked a boring office job and they fought constantly, but didn’t get a divorce until their kids were grown and out of college.

Matt was a smart kid, too smart for his own good. From a young age, he was bored and started acting out in class just to entertain himself. He was constantly getting in trouble in elementary school for trying to crack jokes and disrupting the class. He was labeled a problem child until the third grade when a teacher even considered that he wasn’t a dumb kid, he was just bored and couldn’t sit still. He ended up getting tested and being diagnosed with ADHD. After that, he was still the class clown, but at least he was able to sit still.

He excelled in high school, when he was finally able to take classes that challenged him enough to keep his brain occupied. And it was in his sophomore year honors english class that he met his first girlfriend. Despite Matt being the class clown that was friends with everyone, he was still awkward as hell when it came to girls. He asked her to go to the homecoming game with him, which was awkward and uncomfortable, considering neither of them knew anything about football, nor did they care about it. Thankfully, neither of them knew how to admit they didn’t want a second date, so they went on another one. This time it was to a bookstore, a place they were both comfortable in. What was only supposed to be an hour, turned into hours of them browsing the aisles of the bookstore, laughing and talking.

When it was time to go to college, Matt got into the University of Pennsylvania, with the plan to go premed. His girlfriend went to school in New York, and despite the fact that most high school couples didn’t make it past Thanksgiving break, the pair managed to make it work. It wasn’t uncommon for them to find the cheapest bus they could and see each other every few weekends, even if they spent the majority of the weekend studying together.

In college, Matt was a social butterfly, joining clubs and going out on weekends. He made friends everywhere he went, something that is still true today.

After graduating with honors, Matt took a year off to apply to medical school, and to focus on getting married to his high school sweetheart. They had a small wedding, promising each other they would have a bigger wedding to renew their vows once they both finished their schooling and had some money. Unfortunately their marriage didn’t last. Matt went to medical school in Massachusetts, and his wife wanted to stay in New York for grad school. They weren’t in a place where they could put their relationship first, unfortunately. And despite how much they loved each other, it wasn’t enough and they filed for divorce before their first anniversary.

Heartbroken from his divorce, he made his way through his first year of medical school. He was experiencing health issues, but he assumed it was stress from school and divorce, and told himself it would all clear up once his break rolled around. Unfortunately it didn’t and his sister forced him to go to a doctor to get checked out. After a whole slew of tests, he was diagnosed with lymphoma. As a result, he took a year off of medical school to undergo treatment and recover. Thankfully, he has been in remission ever since.

Matt has found his home in Chicago and he hopes to stay once his residency is complete. Thanks to his outgoing and friendly personality, he was able to make tons of friends, even though his job doesn’t always allow him to see them. And although he isn’t always the most present friend, he is the most loyal. He will drop everything for those he cares about, and do anything for them. And he’s sorry he didn’t respond to your text three days ago, he wasn’t ignoring you, he just forgot. When he has free time he is usually exploring the city, making conversation with anyone who is willing, and befriending the few people in town he hasn’t already.

[dreamingkitsunewrites]

Hey homie, here's a question:

How would you interpret the meaning of Heart-Shaped Box by Nirvana?

Hey friend 💜

I love this question, and I’m honored to share my thoughts with you 😻

I’m actually pretty curious about this mysterious topic because Nirvana is one of my favorite bands. I even read an entire biography about In Utero back in the day, so please forgive my rambling in advance 😂

(possibly triggered and upsetting content under the cut)

Both the lyrics and the music video of this song have this haunting, surreal vibe. The fact that part of it recreates a hospital setting probably refers to a visit the band made to a pediatric hospital shortly before the song was written, which apparently left Kurt particularly moved. ("I wish I could eat your cancer when you turn black")

The subject of the song is definitely his relationship with Courtney Love, which seems to have been troubled, especially toward the end. The "box" in question could refer both to the gift Courtney gave him and also act as a metaphor for, well... feminine private parts (which could tie into the idea of a "toxic relationship based on sex"). "I've been locked inside your heart-shaped box for weeks"

Personally, I believe there’s much more behind both the lyrics and the video, reflecting Cobain’s unique insight into the world and his personal struggles. For instance, the imagery of Jesus on a cross in a field of poppies, which clearly symbolize drugs. And the numerous references to abortion, pro-life movements, and critiques of the Church.

I even like to think of the entire meaning as a visual, visionary interpretation of Nietzsche’s "God is dead" theory, but that’s just my own thought...

I don’t know, I feel like I’m rambling too much. I hope my thoughts make sense to you (sometimes I question my own brain 😂).

Now I’m curious—what do you think about it? 👀💜

[ask-head-of-oncology]

OC Introduction Post!!!

Dr. Francesca Scott

Head of Oncology at PPTH (after Wilson leaves in S8)

Birthday February 15, 1976, 36 years old

Cisgender, currently questioning her sexuality, she/they

6 foot, 4 inches tall

Hazel eyes

Mid-shoulder length, thick, curly black hair

Vascular birthmark on the right side of her body, has a few patches on their face, neck, torso, arms, and legs, with the majority of the birthmark concentrated on her hands and feet

Jewish

Distantly related to Cuddy, Francesca's mother is Cuddy's cousin

Backstory

Francesca is an only child. She grew up with a lot of pressure put on her by her parents to succeed academically. Because of this pressure put on her her entire childhood, Francesca feels that if she is not succeeding at everything in life, she is failing the people that she loves.

Francesca was diagnosed with a brain tumor at six. The tumor was at an inoperable size, so she underwent chemo to try and shrink the tumor. After her chemo plan ended, the tumor was still at an inoperable size. The doctors estimated that she only had a year left to live. One of her doctors convinced her parents to try chemo for just a bit longer, and after this it was discovered that the tumor had miraculously shrunk to an operable size. The doctors were able to remove the tumor, and after more chemo and radiation therapy, she was declared cancer-free. Francesca has now been in remission for 30 years. It was because of this experience that Francesca decided to become a pediatric oncologist.

They have officially been nicknamed "Wilson" at the hospital because they share many of Wilson's little mannerisms, and because they have also been married three times. Her first husband was abusive, and she divorced him after he hit her for the first time. Her second husband was the love of her life, but he died in the same car crash where Haven (he's my other OC who she's in a QPR with) lost his leg. Her third husband didn't want kids, and Francesca divorced him when she discovered that he had been cheating on him.

She was diagnosed with depression after her second husband died and Haven lost her leg in the car crash. They had depression before this point, but the crash pushed it past the point where she was normally able to deal with it. However, she often forgets to take her antidepressants due to the chaotic nature of her job.

Francesca wants to be a mother more than anything. However, she has had a variety of problems with trying to adopt and foster, and she is unable to conceive herself due to infertility caused by her chemo as a child.

Worked as the Head of Pediatric Oncology at another hospital for about three years before coming to work at PPTH.

Profile picture!

[thefreethoughtprojectcom]

The researchers found that a 10% increase in pesticide mixtures was associated with a significant rise in certain pediatric cancers.

Read More: https://thefreethoughtproject.com/new-study/new-study-links-multiple-pesticides-to-higher-brain-cancer-rates-in-children

#TheFreeThoughtProject

[lostfan23]

LOST 2024 AUCTION IS NOW OPEN!

From the website :

Bid Together, Buy Alone! The 2024 Cancer Gets Lost Online Charity Auction is now OPEN! The auction closes on May 18 at 1pm ET, numerically - one at a time! IF an item receives a bid in the final minute it is open, bidding will extended for 2-3 minutes. This will occur up to 3 times before a final bid is declared the winner. *PLEASE read all registration instructions and global shipping restrictions below BEFORE registering. Thank you!*

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[intermundia]

@ anon with the lovely hospital AU, apologies for the delay i was chewing on this for a couple days haha there's a whole season of grey's anatomy primetime soap worthy material. i love how fully you've filled out the AU with characters and unspooled all the drama. i can see why it would be difficult to write, it does have a big scope of imagination there. thank you for sharing it with meeeeeee

for everyone 700 words of lovely obikin hospital AU worldbuilding, continued beneath the cut!!

Shmi is a renowned heart surgeon. Best there is in the country (not just the state thank you very much) and she did it all while her son was young. Her grandmother (Grandma Mira) and her two cousins (Peli Moto and Beru Whitesun ) both helped her out a ton. She is admired and Skywalker is a name very well known in medical circles.

She decided to became a heart surgeon when her own mother (insert name here) died from a heart issue that no one wanted to touch surgically. Anakin was 9 years old. Anakin has his mom up on a pedestal - she is perfect and smart, the best surgeon, the best mom, she’s done it all. Anakin feels the pressure to be just as good as his mom. People expect him to be just as brilliant and successful as his mother. He expects it from himself. Shmi just wants him to be happy. Anakin is ready to start his residency at 25. His mother is in line to be chief of surgery at the hospital she works at (Twin Suns Medical Center). Its considered the hospital to intern at if you want your specialty to be heart surgery. Anakin isn’t really sure what he wants to specialize in, and he doesn’t want people to say that he got it easy during his internship. So he goes to the next best thing (it’s actually the number one hospital overall in the country but to Anakin is second to the hospital where shmi works because Shmi works there). He goes to Jedi Coruscant General Hospital. Chief Executive officer (in charge of whole hospital) : Breha Organa Chief of Surgery : Bail Organa (general surgeon) Brain Surgeon (top brain guy in the country) : Obi-Wan Kenobi 4th year resident: Padme Amidala (Anakin’s assigned resident) Heart Surgeon: Mace Windu Trauma Surgeon: Shaak Ti Pediatric Surgeon: Plo Koon Neonatal Surgeon: Siri Tachi Plastic Surgeon: Quinlan Vos Orthopedic Surgeon: Qui-Gon Jinn Head of the hospital board: Mon Mothma Cancer surgeon: Jocosta Nu Eye Surgeon: Dooku Vascular Surgeon: Wolffe Yoda - retired chief of surgery and general surgeon Anakin’s cohort: Aayla, Ferus Olin, Rex, Jesse, Echo, Fives 4th Year Residents: Sabe, Clovis, Bly 5th year residents: Depa Billaba, Bultar Swan, Cody Anakin’s running late on his first day, in the parking lot he’s too distracted trying to make sure he has everything in his bag that he bumps into a red head and spills the red head’s hot tea all of his shirt. “shit. Fuck. Sorry. Sorry.” Keeps walking but turns around to walk backwards to meet the really pretty blue eyes of the definitely pissed off red head “I owe you. I’ll bring you a … a coffee? Was it coffee during lunch. Sorry!” Ferus Olin, a childhood nemesis makes his appearance. He’s assigned to be Padme’s intern (the woman who gave him back his engagement ring when he was 22 and 27. He hadn’t realized she was back in town and that maybe it was purposeful that he didn’t know). Its turning out to be a truly shit day and then the pretty red head from the parking lot makes his appearance and anakin wants to sink into the ground. But. The red head picks him to help him with a surgery. … Its pretty much a grey’s anatomy AU. Obi-Wan and anakin start hooking up pretty much immediately. Ferus Olin and Anakin make nice and turn out to be pretty decent friends. Then. Anakin realizes that Padme had kids, with him. The twins. And never told him. 🤯. That’s smoothed over. He’s a dad now. He loves it. Obi-Wan’a supportive. Their secret relationship is starting to not be so secret anymore. Then. obi-wan’s ex wife (Satine Kryze) pop in with a kid. obi-wan’s kid. Obi-Wan never told him that he’d been married or that he had a kid. They break up. Anakin thinks about quitting. Then about transferring. Then gets side tracked because Aunt Beru (his mom’s cousin) got married and her husband’s dad was in a bad car crash. Its all hands on deck to save his life. Shmi makes an appearance at the hospital and Obi-Wan realizes that Anakin is Shmi’s son 🤯 Owen’s dad makes it. Anakin and Obi-Wan make up. Their relationship is outted but everything works out. There’s other small and big dramas but thats pretty much it lol