#parkinson disease

[liquidgirl13]

Richard Lewis Dead: Beloved Comic, 'Curb Your Enthusiasm' Actor Was 76

RIP

Shine on!

[pwrn51]

Favre Parkinson’s diagnosis will have fallout

  Brett Favre’s admission that he has been diagnosed with Parkinson’s isn’t just a bad look for the NFL; it’ll have fallout far beyond that. College programs will bring in less money for athletic departments, costing other sports money. For that matter, other contact sports are in the same trouble as the NFL. We are providing the audio commentary with Dan Riley on Brett Favre’s diagnosis of…

[medicomunicare]

Cholesterol in brain network: how does its presence affects health or neurodegeneration?

Cholesterol in brain health and disease Cholesterol is found in the cell membranes of all human cells. It plays an integral role in neuronal signaling and synaptic connections, especially in the brain. Notably, the brain contains between 20-25% of all the body’s cholesterol reserves, making it the organ with the highest cholesterol concentration in the human body. Interestingly, peripheral…

[xceptionallearningindia]

A Case Study on the Impact of Digital Therapy in Parkinson’s Disease Management

Living with Parkinson’s Disease can present many challenges, particularly in terms of speech and communication. Today, I want to share an inspiring story about Gadha, a 63-year-old woman who has shown remarkable progress through digital therapy. Read More: https://xceptionallearning.com/2024/06/19/a-case-study-on-the-impact-of-digital-therapy-in-parkinsons-disease-management/

[regenhealthsolutions]

Exercise should be prescribed for people with Parkinson's: Aarhus University Researchers find

Based on a new study from Aarhus University, researchers recommend that exercise be considered as medicine for Parkinson’s disease and that it should be prescribed as a supplement as early as possible. No pharmacological medication currently available can cure or slow down Parkinson’s disease. However, based on an extensive literature review recently published in the reputable scientific…

[drforambhuta]

Exploring Diverse Applications of Stereotactic Radiosurgery:

The versatility of stereotactic radiosurgery spans various neurological conditions, providing personalized solutions for patients with different medical challenges. Notable applications include:

1. Brain Tumors: Stereotactic radiosurgery plays a vital role in treating both malignant and benign brain tumors. Whether addressing high-grade gliomas, meningiomas, or pituitary adenomas, SRS offers a non-invasive approach to reducing or eliminating tumors while preserving neurological function and quality of life.

2. Arteriovenous Malformations (AVMs): AVMs are abnormal clusters of blood vessels in the brain that increase the risk of hemorrhagic strokes. Stereotactic radiosurgery presents a compelling alternative to traditional surgical removal, allowing clinicians to destroy AVMs with targeted radiation while minimizing procedural risks.

3. Trigeminal Neuralgia: This condition causes severe facial pain and presents challenges in pain management. Stereotactic radiosurgery offers relief for patients who do not respond to medical therapy by selectively targeting the trigeminal nerve and disrupting abnormal pain signals.

4. Movement Disorders: Essential tremor and Parkinson's disease can significantly affect quality of life. Stereotactic radiosurgery allows clinicians to modulate neural circuits involved in these disorders, reducing symptoms and restoring functional independence for patients who have exhausted conventional treatments.

Unveiling the Benefits of Stereotactic Radiosurgery:

Adopting stereotactic radiosurgery brings several advantages to neurological care:

1. Minimally Invasive: Stereotactic radiosurgery eliminates the need for traditional surgery, reducing surgical risks, recovery time, and postoperative complications. This approach enhances patient comfort, promotes quicker recovery, and allows patients to resume normal activities sooner.

2. Precision: Utilizing advanced imaging and targeting technologies, stereotactic radiosurgery delivers radiation with exceptional precision, sparing healthy tissues while effectively treating lesions. This precision lowers the risk of treatment-related complications and improves therapeutic outcomes.

3. Expedited Treatment: Unlike conventional radiation therapy, which may require prolonged treatment over weeks or months, stereotactic radiosurgery typically involves only one to a few treatment sessions. This shorter treatment timeline improves patient convenience, compliance, and minimizes disruptions to daily life.

4. Versatility: Stereotactic radiosurgery can address a wide range of neurological conditions, offering tailored treatments for each patient's specific needs. This versatility highlights SRS as an adaptable therapeutic approach capable of meeting diverse patient requirements across the neurological spectrum.

There are many good hospitals in Mumbai that offer stereotactic radiosurgery followed by regular health checkups to check the success of treatment and also detect and manage any complications due to the procedure, such as a full body health checkup at Jaslok Hospital Mumbai.

[epocheldercare]

By recognizing the early signs, such as tremors, slowed movements, muscle stiffness, balance issues, and changes in speech and writing, caregivers and family can recognize Parkinson's disease and work closely with healthcare professionals to provide appropriate care and support.

[thewitfire]

Advances in Parkinson Disease Treatment

Advances in Parkinson Disease Treatment. #Parkinsondisease #sciencenews

Parkinson Disease Treatment: In a significant development in the field of regenerative medicine, Dr. Andrés Bratt-Leal, co-founder and senior vice-president of research and development at Aspen Neuroscience, has been recognized with the 2023 Biocom California Life Science Catalyst Award. This prestigious award honors young, inspiring minds contributing to meaningful changes in human health…

[bhospicefashion]

Parkinson disease

Parkinson's disease is a condition in which parts of the brain become progressively damaged over many years.

Symptoms of Parkinson's disease are:

involuntary shaking of particular parts of the body (tremor)

slow movement

stiff and inflexible muscles

A person with Parkinson's disease can also experience a wide range of other physical and psychological symptoms.

depression and anxiety

balance problems (this may increase the chances of a fall)

loss of sense of smell (anosmia)

problems sleeping (insomnia)

memory problems

Can Parkinson’s develop memory loss?

Changes in the structure and chemistry of the brain can cause memory and thinking problems in Parkinson’s. Alpha-synuclein, a protein that is central to Parkinson’s, forms sticky clumps, called Lewy bodies, that can disrupt normal brain functioning and lead to dementia.

Lewy body dementia includes two different types of related dementias, distinguished by which symptoms start when:

Parkinson’s disease dementia (PDD) – diagnosed when a person living with PD experiences significant cognitive decline after a year or more of motor symptoms (most typically after many years of experiencing motor symptoms).

Dementia with Lewy Bodies (DLB) – diagnosed when cognitive decline is the earliest symptom, or when cognitive decline and motor symptoms begin and progress together.

Parkinson’s could develop further in dementia, a severe or a lighter variation that can be controlled and balanced. If the brain is not functioning normally due to the Parkinson disease it may cause severe problems with memory loss and forgetting things such as not remembering family members or friends in some situations. This is not always the case as they might gain the memory back.there are easier days and harder days to control this depending on how they are doing.

[pwrn51]

The Emotional Terrain of Caregiving

  Betys’s show today features the remarkable Elliot Sisters—Natalie, JJ, and Emilie. Natalie is the Founder of Sisterhood of Care, LLC, JJ is the eldest, and Emilie is a hands-on caregiver for their mother battling Parkinson’s Disease. In the interview, we discussed the importance of understanding family dynamics in caregiving, emphasizing how recognizing each member’s strengths contributes to a…

[medicomunicare]

An UBIquitous Parkin to take a NAP iSINT BAD while OPTN' for cargo hold: but TANK-binding will lead to a mit-o-loss

There are several pathways to induce mitophagy, or the self-degradation of irreversibly damaged cellular mitochondria. The most well-characterized of these depends on proteins called PINK1 and Parkin, two proteins actively involved in the abnormalities of brain cells affected by Parkinson’s disease. Two other proteins, TFEB and HKDC1, play a key role in the maintenance of both mitochondria and…

[mindblowingscience]

Researchers have identified a series of blood markers that betray the presence of Parkinson's disease up to seven years before most symptoms present. If findings from this small study can be replicated in larger populations, a simple blood test could be developed to identify those at risk. With around 10 million people impacted by Parkinson's globally, there is an urgent need to develop better treatments and preventative strategies. One of the reasons this has proved challenging is our inability to identify people at risk of Parkinson's early enough to trial mitigation strategies. So, University College London biochemist Jenny Hällqvist and colleagues used machine learning models to find eight proteins in our blood that change as Parkinson's disease progresses.

Continue Reading.

[regenhealthsolutions]

Spinal Cord Stimulation helps a patient with Parkinson’s to walk

Gait impairment can be a significant challenge as Parkinson’s disease (PD) advances, with balance problems, frequent falls, and freezing of gait impeding quality of life. Often these challenges do not respond to increased amounts of PD medication or deep brain stimulation (DBS). In recent years, electrical stimulation of the spinal cord has been a research focus to help people with walking…

[beardedmrbean]

Badass

[lady-of-tearshed]

Precious times

Summary: You had never met Azriel's mother. You never dared to ask to come with him when he's visiting her. You discretly test the waters of this subject with him.

Words count: 1.7k

Warnings: slight angst, talking of Parkinson disease, mention of slight injuries

A/N: At your demand... here you go :)💕 I felt like being productive today, so a Azriel fic out, AND I'm going to go feed your deers @thehighladywrites 🤣

The raw weather of Velaris winters engulfed your house briefly when your mate walked into your home. He took off his flying leathers in peaceful silence, as usual. The usual thud of his boots as he puts them down on the carpet announcing the end of his arrival routine. You smile as he gently wraps his arms around your hips, his chest pressed tightly onto your back as you are cooking dinner. He hummed and kissed your jaw softly, his cold lips brushing against your skin making you shiver. He giggles “I missed you today.”

“You always do, handsome.” You smile and slightly turn your head to him so you can kiss him. He kisses you back quickly before slightly pulling back as a smell hits his nose. He doesn’t say a word as you keep stirring the soup boiling in the cauldron and his eyes scan the kitchen. He spots a familiar book spread open on the countertop beside you. “Where did you find this..?” He whispers and frowns his eyes at you.

One thing you knew about the spymaster is that he hated when you were snooping around his stuff. Not that he had things to hide from you, simply there were things he wasn’t ready yet to talk about. “Oh, found this when I placed your folded laundry into your drawer. I thought a recipe from your mother’s cooking book would make you happy.” 

He tenses slightly, then rests his head on your shoulder. “It does, love. It does… Thank you.”

The both of you stay in silence as you keep following the recipe written in his mother’s handwriting. You had never met her since you and Azriel got together. You knew he visited her every year around Solstice, and on special occasions, but he had never offered you to join him. And you knew better than to push him into something. It would only make him shut up like an oyster. 

“Are you going to visit her at Rosehall soon? Solstice is coming.” You start off carefully. He simply nods, his nose snuggled in the curve of your neck.

“I’ve never met her before.” You simply state, testing the waters. He hesitates for a while, then speaks up. “Do you wish to?” 

You spin around and narrow your eyes “Why wouldn’t I? She’s your mother. The one that raised you to the man you are today.”  You smile softly and turn off the oven. You caress his cheek, feeling that there was something more he wasn’t telling you about this topic. 

He bites his tongue, and sighs, trying to release some tension from his knotted stomach. 

“It’s… a bit complicated. She has a disease. neuro-degenerative disease. Parkinson.” He states and places his hand on the one caressing his cheek.

You had never seen him on the verge of tears as he is now. “She can barely talk now, I don’t think you would like to meet her like that-” “Azriel… I just want to meet her and thank her, for you. She seems like such an amazing person…” “She looks just like you.” He admits, his voice shaky. He forces a smile and kisses your lips tenderly. He then whispers against your lips.  “Next week. I’ll bring you with me next week, so we can celebrate Solstice all together.” 

—

You had spent all week wandering around Velaris marketplace with Feyre, digging for the best gift for Azriel’s mother. You had settled your choice on a photo of you and Azriel on the day of your mating ceremony placed in a sculpted silver frame. You had bought her a set of blue sapphire earrings, matching Azriel’s siphons. You were anxiously looking down at the gift in your hands as your lover walked into your shared bedroom. “Love… I don’t want to put pressure on you…” “No, I want to go, Az, really. I just… I want to make a good impression on her.” I want to be good enough for you… 

He lifts your chin up between his fingers and brushes a strand of hair behind your pointed ear. “You don’t have to prove anything. Be yourself, you are perfect in every way, love. I love you. And… she already loves you…” He mutters, red painting his cheeks. 

“You talked about me?” You give him a teasing grin. He grabs you by the hips and leads you towards the balcony, ready for take-off. “A little. Ready?” He says before taking off abruptly, making you shriek and giggle as he holds you close to his chest, his body warm enough to block out the cold winter wind.

—

Rosehall was a lot smaller than what you imagined. A little cottage covered in vines and thorns. It must be an even more beautiful place in hot summer weather, when the roses are blooming on the residence walls and archway. 

When he walks inside the house, Azriel is immediately alerted by the nurses's voices coming from his mother's room. He quickly lets go of your hand but before he goes inside the room, a maid stops him gently. 

“What is it?! What’s wrong with her?!” He suddenly hears a slight groan of pain coming from behind the door the maid was preventing him from passing. “Stop it. You’re hurting her.” He snarls, his siphons glimmering and shadows covering his feet, ready to burst. 

“No, they’re healing her, Azriel.” The old maid, probably familiar with Azriel's protective nature over his mother at this point. You walk slowly towards your mate and place a comforting hand on his tensed shoulder. The nurse takes a softer tone when she notices the anger slightly vanishing from his hazel eyes with only your touch. “Her health is slowly deteriorating. She’s having to develop end-stage symptoms. Her coordination isn’t the best anymore, she’s having a lot of muscle rigidity and even her voice has started to change… We tried to write you a letter, Sir.” 

Azriel’s jaw clenches, and his fingers slightly twitch at the maid's words. An overflowing feeling of shame and self-loathing runs through the bond, making you feel it as if it were your own. Azriel had been busier than ever the past month, and there were piles of unread letters on his desks. The missive from Rosehall about his mother’s health had probably gotten lost in the piles of work on his desk. You squeeze your boyfriend’s hand, it wasn't his fault. 

Before you can tell him comforting words, the nurses come out of the room and smile politely at Azriel “Is she okay?” He asks. “She’s comfortable now. She has a light bruise on her hip, but nothing alarming.” The nurses smile and leave with Azriel's nod of dismissal, the maid moving to let him in.

The sight of the woman lying in bed almost struck you in place, if it wasn't for your mate’s hand pulling you inside. She was exactly like him. The same long eyelashes fluttering in front of the most beautiful shade of hazel eyes you had ever seen, except Azriel’s, those high cheekbones, that sharp jawline, and this smooth tan skin. It was literally how you had imagined her. Her son was definitely the exact perfect portrait of his mother. 

Azriel’s mother's eyes seem to light up, chasing those heavy clouds of tiredness from them, when she sees you moving from behind him. “Eve.” She tries to smile at you, barely able to do so, the muscles from her face tightly and painfully tensed up. 

Azriel sits beside his mother on the bed and kisses her cheek. He pulls you down on the end of the ridiculously large bed and squeezes your hand lightly. 

“Mother, this is Eve.” “The Eve.” She cuts him off, her voice strangely monotone, due to her sickness. Azriel chuckles, “Yes, mother. The Eve… And Eve, this is my mother, Ymir.”

Your heart swells with happiness when you realize how much your boyfriend must be talking about you if his mother considers you as ‘The Eve’. The three of you take the rest of the night easy, exchanging gifts and talking about mostly everything. It’s mostly you and Azriel doing the talking, as Ymir wasn’t feeling all too well. But you didn’t mind at all.

As it was getting quite late, and Ymir was starting to get tired after today’s events, she asked Azriel to tuck her in and play her a song on the big piano placed in the center of the room. A small smile lingers on your lips as you stand next to your mate on the piano seat. His fingers dance on the tiles as he plays a relaxing and comforting song, a song he had probably played thousands of times before, considering the fluidity and accuracy of his notes. As the song finishes he stands up and goes to kiss her forehead, his mother already deeply asleep. 

The both of you quietly make your way out of the house, and you feel the shields your mate had put up, without you even noticing, crumbling down when the front door closes. Tears start falling down his face, just like the snow from the night sky. You hug him tightly into your arms as he silently cries into your neck, his shoulders quivering with each sob. You can’t help but wonder how many times he had to deal with it on his own, how many times he broke down alone without anyone to hold him tight. You want him to know that you’re here, that you’ll always be, and that everything he’s feeling is okay.

“You’re not alone. I’m here.” His sobs get slightly louder, his neck burying even deeper into the crook of your neck. He tries to get lost in your calming scent and to get a grip on his shaky breathing. You stroke his hair slowly, patiently waiting for him to deal with every feeling he’s dealing with right now. “That part is always the hardest… I’m sorry…” “Don’t be. It’s okay to be sad, it’s completely normal, Az.” 

You stay there for a while longer, before he flies the both of you back in your house. The both of you quietly get ready for bed, and put on the matching pair of socks his mother had lovingly knitted. He nuzzles into your neck and holds you close. It felt so good to have someone at his side… He regrets not bringing you with him sooner on his visits. 

“I love you…” He whispers, his voice barely audible. “I love you too, Az.” You answer back before falling asleep.

A/N: Azriel is a very complicated male to write about... there's not much we know about him, actually! Can't wait to see what Sarah J.Maas has planned for us in the next book, I hope we'll learn more about him. 💕😊

[cbrownjc]

Hi! I hope you don't mind getting an ask from me even though we've never interacted.

I have a question about Old Daniel in the IWTV series, but I don't know how to put it except: what exactly is his current health situation? He has Parkinson's disease (or at least they show us ha has some symtomps, and Daniel says it is Parkinson's), but in ep 01 of the first season Louis calls it an "autoimmune disease" (which Parkinson's is not).

They show us that Daniel keeps a bunch of pill containers on his table in his apartment, which makes sense with how Parkinson's would be treated, but then there's the "levodopa transfusion" scene which does not. (I could try to explain the pharmacokinetic reason if you're interested).

And then there's the meals, during which they keep filling his wine glass, the two Martini scenes. . . why do they keep giving him drinks?They arrange for a doctor to come and administer the "therapy" (I'm not buying that it's levodopa), but he can have all the alcoholic beverages in the world? When they most likely would interfere with the pharmacological therapy he's supposed to be taking?

It all seems a bit suspicious to me. What do you think?

(apologies for any mistakes, english is not my first language)

Hi! It's fine to ask me questions even if we've never interacted before, I don't mind. 🙂

So, as far as we know older Daniel on the show has Parkinson's disease for sure. Daniel pretty much confirmed he does because Louis said he had it and Daniel confirmed it in episode 1x01. And the shaking very much shows he does have it IMO. Because he was specifically shown to be shaking back in episode 1x01 when he was trying to put the Fall of the Reble Angles puzzle together.

Now, as many who read my blog likely already know, I've talked about how my mom had Parkinson's and I was her primary caregiver (before she passed away). So I know a lot already about how that disease works. And so when Armand -- as Rashid -- was talking about "levodopa transfusions" for Daniel being scheduled back in episode 1x04 I was very much "WTF?" about that. The whole idea of that is sus because I know from experience that Daniel should just be taking his levodopa via pills. The only time my mom ever got levodopa administered via an IV drip was when she was staying overnight at a hospital.

So I've long thought there is way more going on with that "levodopa transfusions" Daniel got, and have talked about it here and here. Though at the current time, the theory I talk about in those links might be outdated at this point, though I think there might still be a little something to them.

But, if you know the lore, Dr. Fareed -- the doctor who arrived back in episode 1x06 to administer Daniel's transfusion -- is not only a vampire himself but runs a clinic in the books where he looks into and does experiments regarding vampire physiology. And something else that caught my eye about that clinic he runs as I've been reading Prince Lestat, is that it is said in the book that Fareed and his vampire Maker (and lover) Seth, "ran a small clinic for mortal incurables."

And Parkinson's is very much "incurable."

So yeah, I think something is going on when it comes to Dr. Fareed giving Daniel that IV drip of levodopa. Because even when it comes to the idea of cloning, that's a lot to go through just to get something like a blood sample or something I think. But hey, there's really no saying when it comes to that I guess . . .

As to such as Louis calling it an "autoimmune disease" I just chalk that up to either a writing mistake or, hell just Louis being a vampire. He might just not know the correct medical term to use for it. That is also something that is going into in the Prince Lestat book -- how it can sometimes be very hard for vampires to keep abreast of tech and other things at any given time if they do not encounter it or use it regularly. (Lestat is always forgetting and losing his iPhones). As to the alcohol that, again, could just be the show not really looking too closely at such things (because outside of medical shows, many drama shows don't), or maybe Daniel only being allowed one glass a night and being given some okay about it we never saw. Who knows at this point. 🤷🏾‍♀️