#on half of a dose of your antibiotic prescription

[eatyourdamnpears]

when the medications you need to take to get better make you sick, but your mom and doctors tell you that they’re supposed to make you sick before you get better, but it’s the wrong kind of sick, which means you’re not handling them well, and you’re panicking because you don’t know what to do because you can’t live with this kind of sick daily and your mom and doctors are getting more and more frustrated with you for not being med-compliant but you need help to stay med compliant and meds that don’t make your life insufferable, and you’re scared for what the next line of treatment might be since your body isn’t tolerating this kind of treatment anymore

[whisperofsong]

Pairing: Bob Floyd x Female Reader

Summary: Bob is willing to rearrange plans when you fall ill on your birthday.

Note: I was inspired to write this piece because today is my birthday and I’m sick.  As my mom told me, we all have our own methods for providing ourselves with comfort and writing about beloved Bob does just that for me💛  Thank you for supporting my writing!

____________________________________________

When your eyes flutter open on the day of your birthday, you instantly recognize that something is wrong.  Your throat feels tight and when you fetch a glass of water in an attempt to soothe it, it’s akin to swallowing shards of glass.  You wince and your shoulders slump because this can only mean one thing: you’re sick.  On your birthday.  

Fortunately, you had taken the day off from work ahead of time, so you don’t have to worry about that. Nevertheless, you’re disappointed because today is supposed to be a jubilant one; one that entails relaxation and celebration.  Not a day that includes being confined to your bed and feeling miserable.  As you return to your bedroom, you notice a folded note sitting on your nightstand.  It reads, Happy Birthday, Y/N.  I wish I could stay at home with you, but I guess I’ll have to settle for spending this evening with you.  I love you and can’t wait to celebrate the special woman you are.  Love, Bob.

You release a defeated sigh because although it’s your day, Bob is even more excited about it than you.  He’s been discussing it for months, hinting at several surprises, but never giving away too much despite your frequent pestering for information.  Now the day is ruined and the irony of it all is that you’re the one who ruined your own birthday.  

After forcing some food into your system, you get dressed and drive to urgent care.  While it’s only fifteen minutes away, the drive feels endless as achiness settles into your legs.  An hour later, you leave the facility with a positive result for strep throat and a prescription for potent antibiotics.  The line at the pharmacy is lengthy, so you couldn’t be more relieved when it’s finally your turn and your prescription is filled within ten minutes.

Once you arrive home and have taken your first dose of the antibiotics, you consider texting Bob, but decide against it.  Bob is a devoted and doting boyfriend, always seeking ways to console, encourage, and support you.  However, news like this will likely consume him for the remainder of the day, meaning that it could serve as a major distraction at work.  The last thing you want is for Bob’s focus to be compromised, resulting in a trip to the emergency room.  Instead, you decide to nestle under your plush comforter and close your eyes for a little while.

When you wake up, your eyes widen at the realization that you slept for almost four hours. You likely would have slept longer if it weren’t for your clammy skin and the persistent achiness in your lower half. You rifle through the tiny closet in your bathroom until you locate the thermometer, which reveals you have a fever of 101.6.  Yikes. You take some medicine, hoping that it will reduce your fever before Bob returns because you don’t want him to see you in this state.  You look and feel awful.

You try to pass the time by scrolling on various social media apps on your phone and reading a couple of magazines, but your body betrays you as your eyes grow heavy. While you try to fight it, determined to stay awake, you eventually lose the battle and succumb to slumber.  You dream of dinner with Bob, holding hands as you each enjoy a glass of wine, laughing about things only the two of you would understand.  Visions of you two stealing kisses in his truck, his arm securely wrapped around your shoulder while you slightly tug on the hair at his nape, dance in your mind. The dream is perfect and feels so real that you’re somewhat startled when you’re awoken by the closing of the front door.

“Where’s the birthday girl?”  Bob’s exuberant voice echoes through the house and your heart aches at the sound of it. You want to respond, but are incapable of projecting your voice and don’t want to strain it.

“Y/N?” Bob calls once more before you hear the thumping of his feet on the carpeted stairs as he makes his way to your shared bedroom.  His smile immediately falls upon seeing you in bed, looking ashen and depleted.

“What’s wrong?” He approaches you and positions himself on the edge of the bed, laying his hand atop yours that is hidden by the comforter.

You hoist yourself up and wince at how much effort it takes to do so.  The concern reflected in his eyes only increases, thereby causing you to feel worse.  “I didn’t feel well when I woke up this morning, so I went to urgent care and found out I have strep throat.  I picked up the medicine for it, but don’t feel a difference yet.  I also have a fever.”

“Oh, baby.  I’m so sorry.”  Bob sits forward and gingerly cups your cheek in his warm, wide palm.  “What do you need?  A drink?  A cool washcloth to bring your temperature down?  I can make you soup if you’re hun-“

Your sudden flow of tears interrupts Bob’s endearing rambling.  “Baby, why you are crying?” he asks in a voice laced with genuine concern.

You shake your head, your melancholia constricting your throat, making it challenging to speak. You turn your head because you’re embarrassed to be this emotional, especially when he’s being so kind.  However, Bob will have none of it.  You feel his fingertips upon your chin as he says, “Please look at me, Y/N.  You can tell me anything.”  When you finally look at him, you’re met with reassuring eyes, eyes that want what’s best for you.

“I feel so badly, Bob. We’ve both been looking forward to this for months and-“  Snot trickles from your nose, but before you can get a tissue, Bob is ahead of you as he returns with the entire box and holds one out for you with an understanding smile.  You give him an appreciative one and blow your nose before continuing.  “You’ve been especially enthusiastic about celebrating this birthday with me as it’s our first time celebrating as boyfriend and girlfriend and I can’t help but feel…”  You momentarily drift off, reluctant to say the last part aloud.

“Can’t help but feel what?” he prompts.

A sigh escapes you and although you’re tempted to avoid making eye contact with him, you force yourself to meet his gaze.  “I can’t help but feel that I ruined it.  I ruined my own birthday.  I ruined our first opportunity to celebrate it as a couple.  Worst of all, I ruined it for you.”  You sniffle a few times and wipe away the stray tears that begin to travel down your face.

Bob gently takes both of your hands in his own.  “First of all, you haven’t ruined anything.  It’s not your fault you’re sick.  Second of all, today isn’t about me.  Yes, I had some things planned, but plans are bound to change.  That’s part of life.  All this means is that I get to celebrate my best girl another time, on a day that she’s feeling up for it.”

“You’re not…upset with me?”

“Gosh no,” he exhales. “I’m upset for you because you deserve a day that reminds you of the beautiful, intelligent, loving, and special woman that you are to me and so many others that are privileged to be in your life.”

You squeeze his hands and he returns the gesture while his eyes are fixated on you.  “Now, how about some chicken noodle soup?”

“Yes, please,” you reply in a grateful voice.  He presses a lingering kiss on your warm forehead.  “Coming right up,” he answers.

A half hour later, Bob is carrying a tray into your bedroom, the steam from the bowl on it permeating the air.  It also contains a tall glass of water with a bendy straw.  He must notice you eyeing it because he explains, “I figured it may be easier to sip with a straw.”  He carefully places the tray on top of you and folds the napkin on your lap.

“Wait…is this homemade chicken noodle soup?” you ask.

“It is.  You can have the canned stuff any other day of the year, but your birthday calls for something more festive.”

“Thank you, Bob. You’re so thoughtful,” you tell him as you caress his cheek, adoringly staring at the man who owns a significant piece of your heart.

“Anything for my girl.”  He scoops some of the soup with a spoon and feeds you.  You would normally protest such a thing, but realize that while Bob is doing this to comfort you, it also comforts him to know that he’s able to take care of you in a small way.  Therefore, you refuse to deny him of such a thing.  The soup soothes your throat and tastes just as wonderful as it did the last time Bob made it for the two of you.  

Once you finish your soup and Bob takes everything downstairs, he climbs into bed beside you and pulls you to his chest.  He buries his face into your neck and peppers it with slow, tender kisses that cause your entire body to relax while ensconced in his arms.  You turn your head and whisper, “You’re so good to me, Bob.”

“How can I not be?” he asks.  “You’re so good to me.”  He begins to lean down to kiss you on the lips, but you rest your palm on his chest to prevent him from going further.  

“What are you doing? You’re going to get yourself sick.”

“And deprive myself of kissing you?  I’ll gladly take the risk, Y/N.”

Despite being ill, his lips on yours feel right.  If someone had told you weeks ago that this is how you would be spending your anticipated birthday, you would have been forlorn.  However, as you bask in the safety and happiness of your boyfriend’s arms, disappointment is a foreign feeling because you can’t imagine a love greater than this.

 @bradshawsbaby @gretagerwigsmuse @roosterforme @luminousnotmatter @bobfloydsbabe @sebsxphia @mothdruid @dhwanishah09 @ghxst-heart @rhettabbotts

[rosethornewrites]

I saw my new PCP on Monday and got the fun job of explaining my conditions. I’ve previously had doctors who ignored my needs or told me to lose weight, so it’s scary to have to try to convince them that, yes, I am very sick, too sick to work, but I don’t want to be that sick. I miss working. I miss keeping my mind engaged.

So I decided to preface everything with, “You know, a year ago I was a professor at a state university, living in my own apartment. Before I got sick I used to go to a ton of events and travel places. And I spent so much energy pushing through to try to keep going that I burned myself out. Now I am in so much pain and have so much brain fog that even getting out of bed is a challenge. It feels like my life has crumbled around me, and I want to get it back.”

And then I discussed my medical history, what I’ve done to get treatment so far (getting on Medicaid, getting a behavioral health specialist, a dermatologist, a rheumatologist, etc., all involving dozens of phone calls each just to find someone who specializes), the setbacks I’ve faced and how it’s changed how I face seeking healthcare (that all my providers are women is not an accident), and the medications I’m currently taking and what they’re for. How I discovered I can’t have sulfa antibiotics.

It’s a lot—just the medications, I take a biologic injection every two weeks, 2 anxiety medications, an antidepressant that also helps with fibromyalgia, a controlled substance for my pain (NOT an opioid), a medication to control my insulin resistance, an anti-inflammatory, a low dose of antibiotics, and blood pressure medication. Oh right, and birth control, which is supposed to help with the HS. That’s just the prescriptions—I take OTCs and supplements that are meant to help keep my conditions under control because I researched copiously while trying to push through.

How long it took me to be diagnosed with HS (despite telling my PCP at the time I thought I had it, I was diagnosed on sight by a gynecologist two years later, who then referred me to a dermatologist), and the story of how I realized something was terribly fucked up with my body. The struggles with pain. How I take cannabis but hate that it doesn’t allow me to have a clear mind. The years of insomnia, which is a symptom of multiple conditions I have.

I have so many horror stories about my health that my horror stories have horror stories, and those are fun to relate, in graphic detail so they know exactly how bad it is.

It’s this fucked up cycle of having to convince a doctor you’re sick (apparently they don’t want to believe you if you say you are) and actually get treatment, except you get stuck on step 1 because everything must be weight-related and therefore I should just lose weight.

I been fat my whole life. This other shit is new. Catch up.

But then they get mad if you’re “difficult” aka advocating for your health.

Knowing that nearly everyone with chronic illnesses goes this, and even worse than me typically, is distressing.

I knew my chronic pain was fibromyalgia because my mom struggles with it and eventually got diagnosed after being told half her life it was in her head. I was lucky. I have to consider inheriting a debilitating illness from my mom lucky because at least I knew what it was from her experiences.

Every new doctor I see, I feel like I have to vet for egotism because that’s generally the mark of a hot dog who won’t listen or care.

All I really want is treatment so I can maybe get my life back.

[brooklynislandgirl]

"I'm pretty sure I'm not allowed to set you up on dates, Bethykins. Your brother might actually murder me." Before the server could put the offer into words, Tabby liberated a pair of champagne flutes from his possession, passing one to Beth and keeping the second for herself. Tabby never minded being a Riley-plus-one for these galas, except really, she felt Beth could do better. "But if we were playing hypotheticals, let's see. Definitely no one here, and I wouldn't let my worst enemy near that Bruce Wayne dude without a double dose of antibiotics." Tabby tapped the rim of her glass against pouted lip, trying to aid the thought process. "You deserve someone heroic. Or an actual superhero. Maybe Superman. Or Batman even, as long as he treated you right."

Adventures in Matchmaking || Accepting Tabby is not wrong, in the technicality of her comment. But there's worse things Andy can do than murder someone, and he's elevated being annoying to an artform. This is all case-in-point. He'd accepted the invitation on behalf of the family and a guest, then purposefully guilted her into making the appearance for him when she'd much rather be at home in her pjs, reading the stack of books on her nightstand that have started cultivating their own society they'd been there so long. Not that she doesn't love Tabby or her company. That's the only reason she agreed to go instead of threatening to stab her brother in the kidney. Beth drains half her glass in a single gulp, so very unladylike, and nods her thanks to her friend. Her eyes roll beneath thick, mascara-encoated lashes. "You know, Mistah Wayne's problem is...he's alla Andy's bad traits an' none of da good ones. Broody, moody, brilliant but no sense of humour an' ya right. I would nevah wanna be his personal physician. Dey would investigate my license, for over-writing prescriptions." Maybe the champagne has loosened her tongue. Maybe deep down Beth is just as snarky as her absent sibling. She laughs over the whole metahuman remark. She could never imagine herself being romantically involved in someone whose wardrobe primarily consisted of spandex and masks. "See I jus'...I don' get why people fawn all ovah Supahman. I mean yeah he's an alien, an' by all standards da epitome of whatevah-whatevah...but like... is he even compatible wi' humans? We don' really know anyt'ing about him except he save da world sometimes an' he can fly...but...eh..."

Clearly Beth has given this some thoughts. "Same same for Batman. Also... what's wi' da name? Don' get me wrong, bats are really cute an' really soft, an' very important part of da equal system, but how does dat correlate to a crime-fightah in tights? I don' get it." A longer, more thoughtful pause and she looks Tabby in the eye, her voice quite a bit softer. "I t'ink...for reasons...I would hafta choose da Ali'i of Atlantis, or his rival, King Shark. Although, I've gotta admit, if my preferences were to remain in da realm of mortal man, I sorta kinda hope one day Lex Luthor save a dance for me." They both know though that she's really scanning the crowd for her con-man of a magician, John.

[pharmrx]

Clindamycin

Clindamycin sold under the meds brand name Cleocin, is an antibiotic oral medication that belongs to a class of medications called lincomycin antibiotics. It helps in slowing or stopping the growth of bacteria.  It can treat certain types of bacterial infections like lungs, skin, blood, female reproductive organs, and internal organs and helps u have a healthy lifestyle.

This does not work for colds, flu, or other viral infections.  Unnecessary dosage can increase your risk of getting an infection later that resists antibiotic treatment

What: is Clindamycin Bacteria are unicellular living things which means they have a single cell. When observed under a microscope, they look like rods, balls, or spirals in shape. Most kinds of bacteria do not make you sick or cause an infection. Many are helpful. Some bacteria are helpful in digestion, destroy diseases causing agents, and give your body needed vitamins. Bacteria are also used in food preparations like yogurt and cheese for the process called fermentation. Bacterial infection occurs when bacteria enter your body, multiply within the body, and cause a reaction in the body. To cause an infection, bacteria must enter your body

It is advised to follow the directions prescribed by your doctor only. Do not overdose and take it less, as it may lead to adverse effects. Clindamycin’s liquid dosage can be shaken well before each use to mix the medication evenly. You may take the capsules with a full glass of water as it won’t irritate your throat. This medication starts showing results in the first few days of treatment. It is always advised that you must call your doctor if you find your symptoms getting worse.

Uses:

Clindamycin is used for the treatment of certain types of bacterial infections including lungs, skin, blood/Nerve, female reproductive organs, and internal organs infections.  Clindamycin belongs to a class of antibiotic medications called lincomycin. It functions by slowing or ceasing the bacteria. However, the elimination half-life of clindamycin is prolonged in patients with moderate to severe hepatic impairment, If the pill is administered every 8 hours, then dose reduction may not be necessary.

But remember to monitor the plasma concentration of this in a patient with severe hepatic impairment. Depending on the results or improvement, patients may reduce or increase dosage intervals. As of now, you can Buy clindamycin online. Buy clindamycin online capsules and take them by mouth including (those containing clindamycin hydrochloride) and oral suspensions (containing clindamycin palmitate hydrochloride).

Patients with mild to moderate renal impairment do not need to necessarily adjust clindamycin dosages. Whereas patients have severe renal impairment or anuria, plasma concentration is supposed to be monitored while on this medication. Further looking at the results or improvement, patients may reduce or increase clindamycin dosage intervals of 8 or even 12 hours necessary.

Clindamycin is indicated for the treatment of the following medical conditions It is advised to follow the directions prescribed by your doctor only. Do not overdose and take it less, as it may lead to adverse effects. As of now, you can Buy clindamycin online. Clindamycin’s liquid dosage can be shaken well before each use to mix the medication evenly.

You can get a bacterial infection via an opening in your skin like any cut, a bug bite, or a surgical wound. An antibiotic belongs to a category of antimicrobial compounds that are active against bacteria.  It is an important type of antibacterial agent which fights bacterial infections and antibiotic meds are widely used for the treatment and prevention of such infections. As of now, you can buy clindamycin online without a prescription. They either kill or stop the further growth of bacteria

Oral suspension is not recommended for the administration of Buy clindamycin online and to children, due to its very foul taste and odor and is mainly used as a prescribed acne treatment

Naturally With Water

Whereas patients have a severe renal impairment or anuria, plasma concentration is supposed to be monitored while on this medication. Further looking at the results or improvement, patients may reduce or increase dosage intervals of 8 or even 12 hours necessary. However, the elimination half-life of clindamycin is prolonged in patients with moderate to severe hepatic impairment, If the pill is administered every 8 hours, then dose reduction may not be necessary. But remember to monitor the plasma concentration of this in a patient with severe hepatic impairment. Depending on the results or improvement, patients may reduce or increase dosage intervals.

It is available in form of oral capsules, usually taken three to four times a day.

The type of infection and how well one responds to the medication decide the length of clindamycin treatment.

You may take clindamycin thrice every day.

Take the capsules with a glass of water Naturally

Around 150-450 mg every six hours is the usual dose, depending on the severity of the infection. In elderly patients, dosage requirements depend on the severity of the condition. In kids, on the other hand, depending on the severity of the infection, the usual dose is 3-6 mg/kg every six hours. Only children who can swallow should be given clindamycin capsules. Avoid them otherwise. But make sure that you consult a doctor before consuming this. Patients with mild to moderate renal impairment do not need to necessarily adjust clindamycin dosages.

Dosages:

Buy clindamycin online capsules which are taken by mouth including (containing clindamycin hydrochloride) and oral suspensions (containing clindamycin palmitate hydrochloride). Oral suspension is not recommended for the administration of clindamycin to children, due to its very foul taste and odor.

It also comes in a form of vaginal cream and as vaginal ovules for treatment of bacterial vaginosis. It is also available for topical application in gel form as a lotion and in a foam delivery system (each containing clindamycin phosphate) and a solution in ethanol (containing clindamycin hydrochloride) and is mainly used as a prescribed acne treatment. 

You may take the capsules with a full glass of water as it won’t irritate your throat. This medication starts showing results in the first few days of treatment. It is always advised that you must call your doctor if you find your symptoms getting worse. This can also treat acne.  When combined with other medications, it can also treat anthrax and malaria.

 Besides, it can also treat ear infections, tonsillitis, pharyngitis, and toxoplasmosis. Bacterial vaginosis, infection of the heart valves- endocarditis as a result of a dental procedure can also be treated by clindamycin. This detailed study was done by a research team.

Pure & Natural

Except for drowsiness, Clindamycin oral capsule may cause other effects like  unpleasant taste in your mouth. These effects are mostly mild, but if they persist for longer then you must consult your doctor.

Antibiotic-associated diarrhea with the following symptoms:

severe diarrhea

bloody diarrhea

stomach cramping and pain fever

dehydration

loss of appetite

weight loss

Severe skin rashes, such as Stevens-Johnson syndrome and toxic epidermal necrolysis with symptoms like:

severe rash

peeling skin

swollen face or

tongue

blisters on your skin or

blisters in or around your nose, mouth, and eyes.

Here are some common effects of Clindamycin and some very serious effects of Clindamycin: nausea, vomiting, unpleasant or metallic taste in the mouth, joint pain, pain when swallowing, heartburn, white patches in the mouth, thick, white vaginal discharge, burning, itching, and swelling of the vagina. The serious list is as follows: peeling or blistering skin, rash, hives, itching, difficulty breathing or swallowing, hoarseness, swelling of the body areas of the face, lips, tongue, throat, eyes, hands, feet, ankles, or lower legs, yellowing of the skin or eyes, decreased urination. Immediately inform your doctor or pharmacist if you experience any of the above-mentioned or different effects. Do not ignore them.

Medication Information

This can also treat acne. When combined with other medications, it can also treat anthrax and malaria. Besides, it can also treat ear infections, tonsillitis, pharyngitis, and toxoplasmosis.

Bacterial vaginosis, infection of the heart valves- endocarditis as a result of a dental procedure can also be treated by clindamycin.

This detailed study was done by a research team. It is important to keep all medication out of sight and reach of children as many containers are not child-resistant and young children can open them easily.

 As of now, you can buy clindamycin without a prescription, To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location 

Storage:

Keep it in the same container it came in. Close it tightly and store it out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not refrigerate clindamycin liquid because it may thicken and become hard to pour. Dispose of any unused clindamycin liquid after 2 weeks. 

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location –one that is up and away and out of their sight and reach.

Talk to your pharmacist for medication information or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website for more information if you do not have access to a take-back program.

Bonus tips:

Tell you, doctor

If you are allergic to clindamycin & Lincomycin (Lincocin)

If you are allergic to medications, or ingredients like aspirin or tartrazine present in these capsules or solutions.

If you are planning to take any prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products.

If you are allergic to clarithromycin (Biaxin, in PrevPac), erythromycin (E.E.S, E-Mycin, Erythrocin, others), indinavir (Crixivan), itraconazole (Sporanox), ketoconazole (Nizoral), nefazodone, nelfinavir (Viracept), rifampin (Rifadin, in Rifamate, in Rifater, Rimactane), and ritonavir (Norvir, in Kaletra).

If you have or ever had asthma, allergies, eczema, kidney or liver disease.

If you are or planning to become pregnant,

If you are breastfeeding.

If you are having surgery, including dental surgery.

These US-based pharmacy precautions will help your doctor change the doses of your medications and decrease the chances of effects caused by clindamycin.

Treatments: Clindamycin

Many antibiotics like it may cause the over-multiplication of dangerous bacteria in the large intestine area. This may cause mild diarrhea or may cause a life-threatening condition called colitis (which is inflammation of the large intestine). Medication is more likely to cause this type of infection than other antibiotics, so it should only be taken to treat serious infections that cannot be treated by other various antibiotics. 

Inform your doctor that you are about to Buy Clindamycin Online if you have or have ever had colitis or other conditions affecting your stomach or intestines. It is considered safe for pregnant and breastfeeding women.  But it is still advised to consult your doctor before taking this medicine because, in a few rare cases, some effects are observed in the newborn. As now you can buy clindamycin without prescription, Inform your doctor if you have any allergies.

Clindamycin is an anti-bacterial medication that slows down or stops the bacterial growth of infectious bacteria in your body.  Take this medication only if prescribed to you by your doctor in case of severe infection caused. Follow the prescription and complete your course of medication even if you feel like your infection is under control. Do not misuse this med.

Conclusion

The Food and Drug Administration (FDA) warns about mild or serious diarrhea conditions caused by most antibiotics. It can cause Clostridium difficile-associated diarrhea (CDAD). It is advised by the experts to seek immediate professional help if you come across any life-threatening effects while on clindamycin medication as per the research

[acepalindrome]

Lots of people are sick this time of year, so it’s a great time to remember that if you get prescribed an antibiotic, YOU NEED TO TAKE IT ALL. Don’t only take half, don’t stop when your symptoms go away, TAKE IT AS DIRECTED AND FINISH THE PRESCRIPTION.

I sometimes see people talking about trying to save antibiotics to save money or give half a dose to a sick family member or friend, but you really really should not do this. The point of antibiotics is to kill the bacteria that’s causing the infection that made you sick. Taking the whole prescription helps ensure that the bacteria is completely wiped out. So what happens if you stop taking them halfway or when you start feeling better? If the bacteria is still in your system, it can keep multiplying and come back and make you sick all over again. And worse, since the bacteria has been exposed to the antibiotic, the bacteria can become resistant to antibiotics, and that’s real bad news. If the bacteria becomes resistant, it’s much much harder to treat, and can get really dangerous really fast. You can end up with sepsis and that shit can do very serious damage to your body if it doesn’t outright kill you.

Don’t fuck around with antibiotics. Take them exactly as directed and call your doctor if you have side effects or start feeling worse. Infections are no joke.

[offtorivendell]

Skincare routine?? I know some of it, but I want all the deets

To be fair it's not really interesting. It's more a very long and convoluted story haha, but I'll be brief¹ ish².

TL,DR: acne + sensitive skin is a fun combo, and less is more, imo.

I was wrong.

Very wrong.

I've always had sensitive skin, but adult/cystic acne hit me hard after I changed my birth control in the second half of my 20s. Most acne products I tried were too harsh on my skin - I've reacted badly even to "sensitive" products and had to run back to the makeup shop after ten minutes for a wipe to remove whatever it was I'd tried and still ended up with a layer or two of skin burnt off and bumps all over my face for a few weeks - so while the benzoyl peroxide or salicylic acid etc may have worked for others, for me they just destroyed my moisture barrier and left me with acne AND extremely irritated skin -> worse acne than I had to begin with.

After a year, I went to a dermatologist - cystic acne isn't just a knock to your self esteem, it can actually hurt - and the topical clindamycin helped a bit, but it wasn't enough. The oral antibiotics I was prescribed just made me vomit (hooray, new-found allergy) and the differin gel made me peel like crazy, as we've established my skin had no moisture barrier left.

Eventually, after maybe another year, I tried one of those online prescription delivery services for skin concerns, because I was desperate and figured why the fuck not? I couldn't even wear scarves in winter because they hurt the cysts, and I couldn't cover the acne with makeup, because it just highlighted everything and made my face look ten times worse. I'd tried everything else, nothing worked, and I was miserable.

The prescription worked.

Honestly I cried at one point, I was so relieved. When you have awful cystic acne, you feel gross (or I did, anyway), as if you are being judged for a lack of hygiene when you probably put more effort into keeping your skin clean than most people out there. 😅 It took a wee bit over 6 months, but it eventually cleared up by about 90% (the last 10% healed as the scarring and red marks etc faded). Obviously cystic acne is far from the worst thing out there, but it's still not fun, and some of the looks and questions from strangers - "have you tried drinking ACV?!" - get old quickly.

So, what worked for me back then?

A super duper gentle face wash, no exfoliants or anything else fancy.

The cream I was prescribed was really gentle, too, with small doses of clindamycin, azelaic acid and zinc pyrithione. Once a day.

A light moisturiser over summer, with SPF, or a richer moisturiser over winter, also with SPF.

What works for me now, a few years later?

I still use a gentle face wash - 'La Roche Posay hydrating gentle cleanser' - once a day (or twice if I'm wearing makeup). If not, I use a microfiber towel and water to wash my face before bed. As much as I'd love to steam myself in the shower, too much washing irritates my face in the long run.

I tried a slightly different formulation from the same prescription service for 6 months, with retinol instead, but I was always slightly peeling, my skin never got used to it, so I'm back on the original formula, once a day, and my skin is still clear barring the occasional hormonal pimple.

Over winter I'll add in a serum to boost the hyaluronic acid, because I get very dry very quickly. I really like the 'Intraceuticals' brand, though they aren't cheap, but one bottle lasts me 6 ish months, so it's not awful and I'm happy to splurge.

Currently liking 'The Ordinary Natural Moisturising Factors + HA' over summer, or 'Embryolisse Lait Creme Concentre' for winter.

Neither of those moisturisers have SPF, so I use IT Cosmetics CC cream with SPF 50+ for the day and/or Bare Minerals SPF 25 year round, because when you grow up in Australia you learn not to fuck with sun exposure. If I need a normal/untinted sunblock for my face, 'Cancer Council' brand for sensitive skin is good (and I use their regular mineral sunblock for the rest of my body, too). If I'm going out at night, I use a Charlotte Tilbury foundation, which doesn't have any SPF but I still love it. I've been okay with other mineral sunblocks, but some of them leave a white cast even on my pale skin, which isn't ideal.

I tried 'Dr Dennis Gross's Alpha Beta Exfoliating Body Treatment' wipes - I think we spoke about them a while back? 😅 - and they're good! A bit pricey, but luckily I don't need to use them constantly. Still, bacne sucks over summer.

It's not skincare, but skincare adjacent: in terms of makeup, I don't wear a lot, but I like Glossier (mascara, brows and blush cream), Charlotte Tilbury (foundation, eye shadow, blush powder, bronzer, mascara and lippy), Bare Minerals (mineral veil finishing powder and eye shadow), Stila (colour correcting primer and eyeliner). And paw paw balm for lips, of course lol. I tend not to be all that adventurous once I've found something that works, for obvious reasons.

So basically, I do the following:

AM

Wash/cleanse

+ HA serum in winter

Moisturiser + sunblock (then maybe makeup)

PM

Wash/cleanse

Prescription cream, + HA serum in winter

Moisturiser only

So yeah, no 27 step beauty regimen for me, because firstly I can't be arsed, and secondly, chances are I'd react to something and spend a month babying my skin back to baseline. I'd love to be one of those people who can use all natural skincare or try almost anything once, but unfortunately it never works.

Stay tuned for me spending my time and money figuring out how to fight the inevitable fine lines and wrinkles without retinol. 😂

Weirdly specific asks.

[rosemochi]

16

16. Daybreak.

"How much for a room?"

The innkeeper stares. Zack stares back. He knows he's getting blood all over the floor, but it's not as if he can help it, and if the man declines to help him, then the puddle will just get larger. Finally, the innkeeper sighs, and Zack's shoulders sag in relief. "Hundred gil. Only got single beds, though."

He limps towards the desk. It takes a great deal of effort to grab his wallet, considering Cloud is still slung over his back. "That's fine." After a pause, he says, "Sorry about the mess. I'll clean—"

"Don't worry about it." The innkeeper hands him a key. "Room charge includes a cleanin' fee."

Their accommodations are filthy, but it's still better than the lab. Zack sets Cloud down on the bed, strips him of his wet clothes, and covers him with as many blankets as he can find. He still looks uncomfortable — because anybody would've been uncomfortable on such a thin mattress — so Zack takes his own pillow and shoves it underneath Cloud's head, leaving his own side bare. Finally, he collapses into a nearby armchair and watches Cloud with half-lidded, heavy eyes. "What are we gonna do?"

Cloud doesn't answer, of course. The only noise that greets Zack is the sound of the slums outside the window; the bustling crowds, loud, inhospitable, naturally wary of broad-shouldered men in sleeveless turtlenecks. It was a miracle that he'd even managed to find this inn, considering most people in Sector 7 avoided him like the plague. "We'll figure it out." Zack's voice is light, airy, confident; the opposite of what he feels inside. "It'll be fine."

---

It's not fine.

The next day dawns. Zack counts out his remaining gil. There's only enough for a week's worth of food, and that's if he stretches it. Going to the hospital isn't an option, and it's far too late to take a potion, so he eventually resorts to digging out the bullets in his torso with a pocket knife. They make a strange kind of music as they hit the bathroom sink, clinking against the porcelain, accompanied by the steady drip, drip, drip of Zack's blood. Cloud sleeps through Zack's grunts of pain, which he's grateful for — he doesn't want Cloud to see him like this.

As Zack bandages his wounds, he thinks back to the encounter that gave him all of these injuries to begin with. He's pretty sure Cloud didn't get hit by anything, but it's not as if he's conscious enough to say otherwise.

"Sorry, buddy," Zack says. "Gotta do this."

He lifts the blankets up. Cloud's torso looks fine — other than the keloid scar in the center of his chest, stark against his pale skin, and the frightening way his ribs stick out from his body, made thin by five years of stillness and artificial nutrition. Zack doesn't look for very long, because it feels weird; he's oddly flustered by the time he finishes his pseudo-examination.

Once he's finished, Zack goes to sit on the side of the bed and misses it entirely. He slowly sinks to the threadbare carpet, his shirt catching on the rough comforter as he goes down. His head is pounding, as if somebody's hammering on the insides of his brain with a hammer. "Good," he murmurs, relieved. "Just me, then."

---

Zack wakes, his head still aching, and hastily dresses in the only outfit he has. He wants to run his errands before the slums awaken, but Sector 7 is full of early birds... that are naturally wary of Shinra-issued super-soldiers. Zack arrives at a grocery store, dressed in his infamous uniform (sans pauldrons, though it doesn't help much), beelines for the produce, and promptly gets spat at over a bushel of carrots.

"I'm an ex-SOLD—" Zack sighs. The old Wutain woman walks away, muttering curses under her breath. "Nevermind."

He heads to a nearby clothing store and spends far too much money (five gil) on a new set of clothes. The turtleneck, belt, and pants find their way into a nearby dumpster. Now incognito, Zack quickly buys some necessities — food, water, more bandages, a bar of soap — and races back to the hotel room, eager to check on Cloud.

"I'm home," he announces. Cloud doesn't respond. Zack sits on the side of the bed and rifles through the grocery bags, emerging with a container of fruit. "I bought blueberries." He hastily covers his mouth with his other hand as he coughs, his chest burning from the exertion of running up the stairs. "Your—" Another cough. "Your favourite."

---

Could he be a mercenary? He doesn't see why not, really, other than the fact that somebody might recognize him (when he's supposed to be dead). Could leveraging his ex-SOLDIER status help drum up more business? Is it worth the risk? He'll figure it out in the morning, he decides. Zack lies his throbbing head down on the mattress and falls asleep, dreaming of the painkillers he'll buy with his mercenary money.

The fourth day comes. Zack opens his eyes and hisses in pain; the sunlight feels like it's burning a hole through his skull. He flips onto his stomach, seeking darkness, and hears an unfamiliar groan.

It takes him a moment to recognize the sound.

Zack leaps out of bed and immediately sways on his feet. Something is wrong, terribly wrong, but he can't let whatever it is stop him — Cloud needs him. He grabs a bottle of water, brings it to Cloud, and holds his head up so he can drink it.

As soon as the bottle's empty, Cloud asks, "Where are we?"

"Sector 7," Zack says. "The slums."

Cloud's eyes roam up and down Zack's bare torso, pausing at the blood-stained bandages. "I remember the cliff," he croaks. "I thought I dreamed it."

Zack lays back down on the hard mattress. He laughs, but there's no humor in the sound. "I wish."

The mattress squeaks as Cloud turns to face him. Zack carefully looks at him, emaniciated but animated, taking in all of the features — sunken eyes, sharp cheekbones, dry lips — that display his illness, equivalent to Zack's own sorry state. Still, there's something about the sight of Cloud that Zack finds strangely wonderful, something that makes his heart race — a feeling made stronger by the fact that it's him, awake, present, right beside him.

"We're alive," Cloud whispers in wonder.

"Yeah." Zack smiles. "We're alive."

---

Though Zack might not stay that way for long.

Day five. The morning sun burns his eyes like acid. Whatever's been plaguing Zack has grown infinitely worse, and he suspects it has something to do with one of his bullet wounds — whatever's making his bandages stain yellow rather than red. Or perhaps it's because he sat in soaked clothes for hours upon hours as he hauled Cloud to Midgar, frozen to the bone in the frigid December weather.

Or perhaps it's both.

The reason doesn't matter, really, because that's not the point. Isn't he supposed to be immune to these sorts of things? What on earth was the point of his augmentations if he still gets things like colds and infections?

Zack ventures back outside in search of medicine, for things he hasn't taken since he was a child in Gongaga, fighting against strep throat and bronchitis. He heads to the nearest pharmacy, because he still can't afford a doctor. Unfortunately, he finds out he can't afford basic remedies either.

"You got wounded?" The pharmacist says, eyes wide. "How long ago?"

"Five days."

"Way too late for a potion," he murmurs. He looks Zack up and down, then rifles underneath the counter. "I'm not supposed to sell these without a prescription, but..." He rings up the antibiotics. "Two hundred gil."

Zack grimaces. "I have fifty."

The pharmacist directs Zack to the veterinarian next door: somebody who sells drugs under the table for cheap. Zack pays ten gil for a bottle of canine antibiotics (which is still too much, but he can't take care of Cloud if he's dead himself) and stumbles back outside. His head swims as he wobbles down the street, knocking shoulders with Sector 7's many residents. He hits one woman particularly hard. "Sorry," he slurs.

The black-haired woman whirls around to face him. She gasps. "Wait—"

"Sorry."

The woman says something else, but Zack rushes forward, eager to get back to Cloud. He makes it back to the inn (though he's not quite sure how), tears his way back into the room, and promptly rushes for the toilet. The bile tears through his esophagus as it comes up, leaving his throat raw and scorched in its wake.

Something crashes in the bedroom. Zack looks over the rim and sees Cloud crawling towards him, a blanket tangled around his legs. "Are you okay? What happened?"

"Nothing," Zack insists, though he's sure he's not doing a very convincing job of it. He flushes the bile away. "Got meds."

Cloud hunts around for the bag that Zack dropped on the floor. Exhausted, he leans back on the bathroom cupboard, rips the bag open, and inspects the bottle. "This says 'for Fido'."

"He said something about 'equivalent doses'," Zack groans. "No idea what that means."

Somehow, he musters up the energy to pull himself up to the sink so he can brush his teeth. Cloud crawls up with him, using the counter as leverage. The image in the mirror is a frightening sight; Zack can barely recognize himself. Cloud reaches up and pulls a sweat-soaked strand of hair from Zack's temple. "When was the last time either of us showered?"

Zack grimaces as he thinks back. "Five years ago?"

It's a good thing they decide to shower together, because they end up having to hold each other up. Cloud doesn't have the dexterity to unbutton his own pants, so Zack does it for him; Zack doesn't have the strength to lift his arms above his head, so Cloud hooks his arms underneath Zack's shirt and pulls. They take turns scrubbing each other clean, trying to make up for each other's deficiencies. Zack's bandages get soaked, but he simply doesn't have the energy to care. "Bend down," Cloud says. "I'll get your hair."

The hot water doesn't last long. Strength spent, they end up on the floor, gasping for air and clutching each other for warmth. Zack's feverish forehead lands on Cloud's cold shoulder; the sensation makes him groan in relief, even though the rest of his body is frozen to the bone. "We might have to stay here forever," Cloud gasps. "I don't have the strength to haul you up."

Zack slowly drags his head up. Droplets of cold water drip down Cloud's chin, his jaw, his neck, collecting in the hollow of his throat. Zack's mouth is impossibly dry; if he didn't know any better, he might've tried to drink from it. "I'd be fine with that," he admits.

---

"Why did you give me your pillow?"

Zack drags his eyes open. Dim streaks of light pierce through the blinds, highlighting the dust in the air. The clock on the nightstand reads 5:30 AM. "You needed it more."

"How?" Cloud croaks. "I was unconscious."

Zack doesn't have a good answer for that, so he stays silent. Cloud sighs and tugs at his shoulders. "Roll over," he says, and Zack slowly complies. His head lands in the center of Cloud's chest — a much comfier surface than the hard mattress. "Stupid," Cloud whispers into his hair. "You're so stupid."

They slowly drift back to sleep. Zack dreams of everything — his childhood in Gongaga, his days as a SOLDIER, the bloodshed in Wutai, the pain, the glory, the atrocities, all blending together into a whirlpool of dreams and nightmares. At the center of the maelstrom, always present, is the laboratory and the years he spent with Cloud, so close and yet so far, within arm's reach but miles away. In his dreams, the glass is impenetrable, no matter how hard he tries to smash it; his screams are muffled by the mako that spills into his throat, filling his lungs, robbing him of freedom.

But not anymore.

Cloud is here. He's in front of him, beneath him, warm, breathing and alive. Cloud's arms rise up to hold him, enveloping Zack in a comforting warmth that feels like home; Zack's hands clutch at Cloud's shirt as if it's the only thing tethering him to the Planet. The fabric underneath his eyes quickly grows damp.

"Still feverish," Cloud whispers, his lips moving against Zack's forehead.

"Yeah?" Zack mumbles, as if he can't tell — though he obviously can. His head is swimming; he feels like a child again, sitting in the bow of his dad's fishing boat, feeling the ocean tug him to and fro. "Not enough dog meds."

"I'll go get them."

Zack's arms tighten around Cloud's waist. "Don't," he says. "They're not doing anything anyway."

"You have to keep taking them for them to work," Cloud argues. He eventually wiggles out from underneath him, though Zack does his best to make him stay put. An eternity passes before he returns, medicine and water in hand. "Open your mouth."

Zack's throat, still raw from bile, aches as he swallows the pills down. Cloud puts the medicine aside and collapses on top of him, utterly spent. They lay there for a while, arms twisted around each other, Zack taking comfort in Cloud's steady heartbeat. "Don't know what I'd do if I lost you," Cloud whispers.

Zack gently runs his fingers through Cloud's sweat-soaked hair. "You'd be fine."

"No," Cloud quietly argues. "No, I wouldn't."

Zack slowly sinks back into unconsciousness. For once, he dreams of nothing; his mind is a dark, cool abyss, a refuge from the fever. When he's pulled back into the world of the living, his surroundings are much of the same. Zack awakens to soft fingers running through his hair, stroking his burning forehead, caressing his sunken cheeks. Is he still dreaming? "Don't stop," Zack croaks. "Feels good."

The stroking continues. The fingers trace his brow, the slope of his nose, the bow of his parched mouth, thumb swiping against his bottom lip — where they suddenly stop. Zack opens his mouth to speak, to breathe, to ask for more, when something else presses against his lips: a mouth as chapped as his own.

The kiss is light, because it has to be; even in his dreams, there's no energy for passion. In its absence, the gentlest of movements becomes profound. Zack sighs as he gently presses his lips to Cloud's, swipes his tongue against his bottom lip, seeking his warmth. A shiver tears through him as Cloud's tongue brushes against his own—

—until Cloud abruptly pulls away. He coughs, his chest rattling as he desperately tries to catch his breath. Zack holds him tight and rubs his back until the coughing fit passes. "Shh," he whispers against Cloud's forehead. "Shh."

Cloud eventually stills. Zack can tell he's feverish too; the skin underneath his lips is hot to the touch. "Sorry," Cloud croaks. The misery in his voice makes Zack's chest hurt. "I'm sorry."

Zack shakes his head. What on earth could he ever be sorry for? "Don't be."

They lay there for what feels like an eternity. Zack drifts in and out of consciousness, through the past and present. The fever tries to pull him under, but he briefly comes up for air. "I'll kiss you properly," Zack croaks, "when we're better."

Cloud's arms tighten around him. "We're not getting better."

He's right. Zack's fever persists, no matter what meds he throws at it; he can feel death hovering nearby, waiting to pull him into the ether. "If you can move," Zack slowly says, "I want you to go to the hospital. Don't—" He coughs. "Don't worry about the—"

Cloud inches himself up Zack's body and kisses him again. He coughs, then kisses the corner of Zack's mouth, coughs, then kisses his cheek; the hacking sound is loud and startling, as if it's tearing his lungs into two. "Shut up," he says. "I'm not leaving you."

Zack's eyes close against his will, robbing him of the opportunity to argue. As he slowly sinks into darkness, he feels something wet drip onto his face, like a familiar droplet of rain from a stormy sky. If he were to open his eyes, would he see dark clouds? Would he still be on the cliff, lying in the torrent, waiting for death?

He opens his mouth to the rain, eager to soothe his parched throat, and tastes salt on his tongue.

---

Zack awakens. The light behind his closed eyelids is warm, soothing, like the sunlight that dries the earth after a storm. A soft breeze brushes against his neck, stirring his hair.

"Hey."

Zack cracks his mouth open. "Hey," he croaks.

The weight of Cloud's body pushes him into the ground. Is he alive? Dead? Has he always been dead? Zack doesn't know much about the afterlife, but he knows it's supposed to be a paradise, and an eternity with Cloud is the closest he'll ever get to it.

The sunlight grows warmer, enveloping him from within. The pain in his body ebbs, replaced by something that Zack can only describe as peace. "I love you," Cloud says.

He turns his head towards the sound. "I love you too," he says, smiling. "Always have."

Another sound slowly enters Zack's consciousness; two sets of heavy boots, smacking against wooden floors. "Somebody's coming," Cloud says. "Shinra?"

Zack wraps his arms around Cloud, holding him tight, tighter, until they're as close as two people could possibly be. Their bodies meld into one entity, one soul, impossible to separate, together for eternity. "I'm not going anywhere without you," Cloud says.

The boots come to a stop. "No," Zack agrees, shaking his head. "Never."

Knock.

Every single thing Zack meant to say over the past five years comes out in a rush. "I love you," he croaks, because he can never say it enough. "I love you, I love you—"

Knock. Knock. Knock.

"I love you too," Cloud says, his voice thick with tears.

"What are you tryin' to do, tear the damn door down?!" the innkeeper growls. "Hold on. I've got a key."

It doesn't matter. None of it does. It doesn't matter what will happen, if they're alive or dead or somewhere in between, if they're spirits wandering through the ether, souls flitting through hazy dreams — because they'll always have each other.

"I love you."

The door opens.

[firespirited]

After 3 months of splitting headache and earache i finally see the doctor, 1 week into antibiotics nothing’s changed, bp is in the toilet, i look like a zombie. I go to recheck my prescription and squint at it from different angles. Notice the 12 at the bottom? hunt through a mountain of papers for my last sinusitus scrip. It’s a 2, i’ve been taking a half dose because my Dr can’t write. I’m both relieved -your brain starts to worry about superbugs from neglect- and really annoyed - and no, annoyance isn’t enough to get your bp up, not that i havn’t tried over the years LOL-.

Anyway, in comes a commission request right as i was feeling like I might not reroot or anything until next spring and just hibernate instead and couldn’t face replying. Now that treatment’s back on track, I’m more hopeful and said Yes. I ended doing a bunch of swatching for nowt as the client *did* mean yarn not fibre LMAO. This is a Clawdia from @musicalmeowsandcandiedlemons who got a semi-failed ethoxylated alcohol treatment as the remaining glue broke down a few months later. Her cute face is so versatile I couldn’t decide between ruby and black with maybe a white or yellow streak or leaning into into blues and greens as contrast colours to make the face pop but that meant researching nylons. Client would like a natural braided look and no wolf ears so I suspect she’s going be human, maybe a vampire! I’ve shaved down her ears and added a dollop of e6000 to each hole, now we wait 3 days for it to set. Clawdia’s got a well designed smile that feels enthusiastic. She’s going to look great with a bigger hairdo. The e6000 setting gives me some time to recoup too.

[msbarrows]

Cataracts - What Surgery Is Like

As previously mentioned, I’d developed cataracts and am now going through surgery for them, and have elected to document a bit about what it’s all like from my viewpoint. Mostly because I think it’d make a nice reference for anyone wanting to write with some degree of accuracy about what it’s like from the inside.

This post contains a description of the surgical process involved and what that actually feels like, I’m trying not to be overly graphic but I’m also not elliding over any of the grosser bits (thankfully and surprisingly very little).

First off, a descriptiong of the preliminaries. This started for me with my vision going blurry over the last couple of years, and finally getting around to visiting my old optomitrist when I happened to be in Toronto over last Christmas (as my one up north just retired a couple years ago, and I hadn’t replaced her yet). Of the several potential causes for the vision loss I was experiecing, what I had turned out to be cataracts, of the variety that occurs at the back of the lens and therefor doesn’t cause easily-visible clouding. Which I actually said “Oh, thank god!” to when the optomitrist told me, since they are the absolute easiest thing to fix, while some of the other options (detached retina, or diabetes-related macular degradation, to name a couple) are much less so. Then he gave me a reference to an opthamologist. Thanks to COVID-19, it was this fall before I was finally able to actually get to the clinic and see her.

From my point of view, the process then went pretty quickly. Note that I was at an eye institute that specializes in cataract treatment; everything is contained in one building (a nicely renovated Victorian brick house in the Annex area of Toronto). So all tests and surgery are done on premises.

First appointment there, they did the same sort of vision tests my optomitrist generally does, plus some extra inner-eye photography to get a good look at what was going on. This was done by two different people, one doing the eye-chart related tests and a different one doing the photography. Then I met briefly with my doctor, who looked over my questionnaire (which included questions like whether near, mid, or distance vision was most important to me, and was there a focal distance I particularly needed to be glasses free for, etc.), and that I didn’t need nor have interest in a lens replacement that wasn’t covered under our provincial health care.

A week later I returned for them to perform eye measurement tests, which are used as a basis for manufacturing the replacement lens. They measure the size and shape of the eye, and mostly just involved staring into various machines while photos are taken. The weirdest one, which they did last, involved dripping numbing drops into my eyes, and then lightly pressing a small sensor to multiple places both directly on the eyeballs and then on the closed lids. Something to do with viscosity I’d assume.

And now for a description of the general surgical process, which you can also find summarized (or in more detail) at a number of medical web sites. In my case, it was a pretty basic surgery being performed; the opthamologist needed to make a small slit in the outer layer of my eye, used a tiny probe to break down the lens using ultrasound waves, vacuum out the broken down lens, then use a largish needle to insert a folded plastic lens into the eye, where it would unfold within the capsular space and could be tweaked as needed into the correct position. The cut in the eye is tiny enough that it usually doesn’t even need stitching, apparently.

I was asked to arrive at a specific time, and had to start applying dilating drops to my eyes an hour, half-hour, and five minutes before leaving for the clinic. No nail polish or facial makeup. Preferable wearing comfortable pants and a loosely short-sleeved button front shirt without any undershirt or long underwear beneath it (which turns out to be a “just in case things go crazily sideways” measure; they didn’t actually need to access anything on my torso).

The first step after I arrived at the clinic was being dressed in PPE - one of their own disposable masks to be sure I was wearing a good enough one (that wasn’t coated in whatever mine had picked up outside), a hair cap, a long-sleeved thigh-length blue plasticized robe (it had thumb holes to prevent the sleeves from slipping), and booties over my shoes.

Then I was taken to their surgical floor, where a nurse began a series of eye drops. These included more dilation, an antispectic, and an antibiotic, that I can remember - multiple drops of all. She also gave me a teeny tiny pill to place under my tongue and let dissolved, which contained a small dose of a relaxant/anti-anxiety med (Sorry, she told me the name of it at the time but it’s dropped out of my memory). I didn’t notice any particular change in my mood, but then I’d been counting slow deep breaths since arriving (4 seconds in, 4 seconds out...) to help keep myself relaxed and give myself something to focus on that wasn’t omfg I’m going to be awake during this! Because yeah, not having a clue what it was going to be like was stressful. Nurse also took my blood pressure to be sure I was fine in that regards, and put a sticker on the gown to remind the doctor that it was my right eye being done that day.

After a brief wait, I was moved into one of the surgical theatres, where there was a dentist chair they sat me in, then connected a blood pressure cuff, fingertip monitor (hence the no nail polish rule) and sensors on the backs of both hands and one ankle (I’m assuming those were measuring a mix of blood oxygenation and heartbeat, with the ankle one making sure my feet were still getting blood when I was spending the surgery in what ended up as a tipped-over-backwards with head lowest position). They then rinsed my eye and the orbital area with bactine (very yellow vision while that happens), then patted the area around the eye dry.

The doctor sat at my head, and applied a medical drape with a pre-cut adhesive-edged opening over my eye, then peeled off a translucent applique that was over the hole. Then they applied medical clamps that held my eyelids in the open position (which thanks to the numbing drops, I didn’t feel at all). A brightly lighted microscope was then positioned over the eye, and I was told to stay as still as possible and stare at the red dot in the lighted area. The doctor then did the surgery as described above. From my point of view, there was very little to feel; occasional dull pressure, some random coldness that I believe was the eye being irrigated. I could hear the occasional very quiet noise the probe made as the lens was sucked away, but mostly it was just staring at the red light as well as I could while my vision distorted oddly and I continue counting breaths. Within what felt like no more than 5-10 minutes (if that), it was all over with.

They had me continue to lie there for a couple minutes while they peeled off the drape, wiped the eye area clean, and removed all the sensors, then a brief rest before having me sit up.

I blinked once or twice, and... DAMN! Sudden near-perfect vision in an eye that hasn’t seen clearly without help since I was in single digit ages. And the saturation. The detail.

Now, my left eye of course still has a cataract (it gets treated next week). I’d been telling people for a while that basically all my right eye was seeing was blur, so my left eye was doing most of the seeing, and I thought my left eye wasn’t anywhere near as bad as my right. With my right eye now seeing perfectly, I could now alternate opening eyes from side to side, and see just how badly (and irregularly) blurred and yellowed the left lens actually is. To which I can only saw, WTF, how was I even seeing anything at all!?

Then they had me sit for a while in the waiting area, where the doctor came and double-checked I was fine, and gave me a kit in a plastic bag of a card that identifies that I have an interocular lens (and info about it), a prescription for two different eye drops (antibiotic and anti-inflamatory) which was enough for both this eye and the eye getting operated on next week, and a shield to wear at night for the first five nights, to be sure I don’t accidentally rub it or put pressure on it.

Then I put on sunglasses (because hugely dilated eye) and walked out.

Side note - they won’t do your operation unless you have a ride home arranged; because that tiny pill means you’re in a slightly altered state, among other reasons. Good thing it was my brother and not, say, a taxi, since among other things it took us three drugstores to find one that actually had both kinds of eyedrops in stock, yay super fun.

Also, remember me talking about the starburst rays I was seeing around lights due to cataracts? While my eye was still dilated (which lasted until after midnight) I was seeing what I can only describe as ‘Ferris wheels’ - a burst of  rays expanding out like the spokes of a wheel, and ending in an uneven ring of dots of bright light, each wheel matching the colour of the light causing it. Looked wild at night. Thankfully that effect has now gone away.

Had a follow-up appointment this morning where they did an eye chart and the rebounce test where they puff air at your cornea, and the opthamologist says the vision in that eye tested as 20/20 (WOOO! Finally something good with that number). I can see sharply and clearly for blocks from the mid-range on out. Sadly when I try to use my computer, tablet, etc (near-range and close vision) the eye can’t focus down far enough; some of that may improve over the next month or two as the eye continues healing, and adapting to the lens. In the meantime my sister suggested I try a pair of her reading glasses and, yay, that worked. I am now planning that after my follow-up appointment for next week’s surgery on the left eye, I’ll run around and pick up 2-3 pairs of reading glasses of various strengths (which I will get will depend on what seems to work best with arm’s length and close-in viewing), to carry me through until I go back to an optomitrist in a month or three, and get my vision evaluated to see if I need actual prescription reading and/or far distance glasses.

In the meantime, apart from computer/tablet use, I am glasses free. I can’t even remember ever having such sharp, clear, and saturated vision (since I’ve been in glasses for such a long time). You know the “oh, trees are made of leaves!” effect? I am getting that with every single thing I look at. Oh, that’s how much grey is in my hair? Weird, I never noticed this wall was textured before. Oh geez, that text over there is so small and yet I AM READING IT. I mean, even with glasses I probably was never able to read that from this distance! Etc ad infinitum.

It’s just so, so nice.

And that’s with just one eye finished. I am now really looking forward to next week’s surgery. Stress? What stress!?

[psychocad]

Cannabidiol, The Wonder Drug of the Future

Cannabidiol, also known as CBD is an important cannabidiol derivative found in marijuana. Cannabidiol is also one of the handful of identified naturally occurring cannabidiols in cannabis and constitutes up to 40 % of the total plant's extract. The other half belongs to another group of cannabidiols called CBG or cannabidiolates. This specific component of marijuana is thought to act as a weaker version of THC, the chemical substance found in marijuana that has been proven highly dangerous to humans. However, researchers have shown that Cannabidiol has some distinct health benefits that may be beneficial to human health.

Cannabidiol may benefit us in a number of ways, one of them being reducing the signs of aging. Research shows that CBD reduces the appearance of 'age' on the skin by acting as an anti-inflammatory and possibly an anti-oxidant. This also means it may prevent some of the damage caused by the damage to our arteries, as well as slowing the aging process.

Since using cannabidiol can help reduce the pain of certain medical conditions like glaucoma, and seizures in epileptic patients, it is being used more frequently in treating such conditions. Glaucoma is usually treated with a combination of aspirin and an anti-seizure drug. The risk of losing control during a seizure can be a major problem for patients using this method of treatment, which many people do not want to undertake. The side effects of taking epilepsy medication, for example, can include loss of consciousness and sometimes death. However, using cannabidiol to treat glaucoma may help prevent a potentially fatal situation.

Another medical condition treated with cannabidiol is epilepsy. epilepsy patients are often given large doses of cannabidiol (and in some cases, a CBD extract) to relieve the pain caused by their seizures. However, because CBD is not able to cross the blood brain barrier, it has no effect on epilepsy patients when it comes to reducing the electrical activity of the seizures. Also, the level of cannabidiol required to relieve the patient's symptoms is very high, which means it would have to be taken on a daily basis over a long period of time to achieve any benefit. This can only be done with the use of a special cannabidiol supplement, which is available from health stores and online.

Cannabidiol, like many other medicinal plants, might decrease the effectiveness of other medications. Research has not established whether or not CBD is compatible with certain types of medications, although it has been shown that it might decrease the effectiveness of at least two medications used to treat serious diseases, such as cancer and HIV. It might even interact with many prescription and non-prescription medications, such as anti-depressants, antibiotics, antidepressants, corticosteroids, birth control pills, nicotine and many others. It is important to talk to your doctor if you intend to take cannabidiol for any of these conditions.

Cannabidiol, because it is not a known metabolism enhancer, may cause sleepiness while it is being used to treat a disorder. This is called side effects, and there are different types of side effects, depending on the disorder. The most common is a decrease in libido, which may cause sleepiness during the daytime. Some researchers believe that cannabidiol might increase levels of melatonin, which might help prevent jet lag.

Sleepiness or lack of sleep, as noted above, is usually caused by other factors, such as anxiety or depression. However, in some cases, the lack of sleep caused by the presence of cannabidiol can be due to an allergy to pollen, environmental pollutants, or a strong odour. Early research suggests that cannabidiol use is not recommended for people who are prone to allergies. In fact, the Food and Drug Administration (FDA) recently warned that there might be an increased risk of dying or going blind from using it to treat ADHD. This is one of the first signs of serious side effects that can occur.

Cannabidiol, like most other plant extracts, undergo phase II of human clinical testing, which is designed to confirm its safety and efficacy in humans. In this phase, scientists use double blind, randomized, placebo-controlled studies to test the effects of Cannabidiol on behavior, health, and wellness. Early research indicates that cannabidiol has some positive effect on neuropsychological disorders such as attention deficit disorder (ADD; also referred to as hyperactivity) and schizophrenia. But the real potential benefits of cannabidiol lie in its potential to treat ailments associated with aging skin and mucosal lining, and inflammation, such as Crohn's disease, ulcers, colitis, arthritis, and even certain forms of cancer. If further clinical trials confirm these indications, Cannabidiol could prove to be an extremely important additional addition to the current arsenal of treatment options for Attention Deficit Hyperactive Disorders.

[justsmilestuffhappens]

Day 2 (11th of February) - “That might just be the least romantic thing you’ve ever said to me” @buddietinesweek

Love sick

Buck was waiting on his doctor to come back with his results. She'd said his throat looked irritated then took a swab.

He wasn't feeling too hot. Or, well that wasn't the right way of putting it. He felt like his skin was on fire to top off his throat hurting.

"Mr. Buckley." She pulled him out of his phone where he was watching short videos while he was alone to try cheering himself up.

"Just Buck is fine." Buck forced a smile once he finished coughing.

"Well, your results came back as streptococcal pharyngitis. Strep throat. That's what's causing your fever. We'll get you on some oral antibiotics." At buck's gulping which made him wince she continued.

 "I'd advise you need to avoid others for a few weeks at the least. You can come back in a week or so for a checkup though. I'm sure you already know not to share any fluids with others." At buck's nod she went on.

 "Be sure to keep as clean as you can as it can be passed on easily to those around you through sneezing and coughing. The nurse at the front desk can take your insurance and set up where you want your prescription to go before you leave. You didn't have any questions sir?"

"But Valentine's in less than a week." Buck groaned.

"I'm sure you're partner would like to stay healthy and you wouldn't want to pass it on to people you love." She said.

"Yeah, yeah. I don't have to like it." Buck huffed as he got up to go.

This was just great. His first Valentine's day with Eddie since last year when they got together after it had already passed. Buck couldn't catch a break. But he'd be damned if he let himself infect Christopher and Eddie with this. He felt miserable and he wouldn’t wish this on anyone.

His trip out towards his jeep and eventually to the store for cleaning supplies and comfort food while waiting for his drugs was a blur. Buck's pretty sure he could double for a zombie with how he looked but made sure to keep to himself avoiding a cart for his arms and hands. His cough drops were helping too.

Soon he was on his way home to spread the news. Casa de Buckley was off limits till further notice. He took his first dose with food and sent out the mass text. Bobby would have to coordinate things till Buck was 100% again.

Buck decided to call Eddie instead though to both be more personal with his boyfriend and hear his comforting voice.

"Hey Buck, how are you babe?" He heard that smile.

"I'm sweating because my brains melting, and my throat feels like a bee stung my insides, but all i can think about is not being able to kiss you or see Christopher,"

"Wait. You're sick? But I just saw you yesterday”

"Yeah."

"I'm coming over."

"No! Eddie I'm not getting you sick with my dick or yours for that matter no matter how hot and sweet you are fever delusions or not and that's final. I'll barricade my door if I have to. Don't test me man. Please," Buck started coughing only to sigh.

“That might just be both the most and least romantic thing you’ve ever said to me”

"Just keep talking. I like the sound of your voice Eds. And I might owe you a rain check for valentine's,"

"Ok. But you're more important than some holiday. Do you wanna talk to Christopher too?"

"Sure. I gotta explain why movie nights cancelled. Let me drink something, "

"It was game night. I'll get him."

"Right. I'm sick cut me a break" buck laughed.

"Hi buck." Christopher's voice brought a smile to his face.

"Hey buddy." Buck replied.

"Are you ok?"

"No buddy I'm sick. But I'll be better in maybe over a week. The doctor got me medicine to help but hearing you guys is good too." Buck said.

Christopher told him about his day after Eddie got home along with Eddie saying what they'd gotten up to at work. Buck replied when he could until he was snoring.

"Daddy, i think buck fell asleep." Christopher whispered.

"Yeah. Say good night."

Christopher did then handed back the phone.

Eddie went to his room. He'd put Christopher to sleep in another half hour. He left the call connected even if someone else might find it odd. Buck was his boyfriend so he could do that right?

He'd fall asleep to the sound of Buck once he put Christopher to bed a few minutes later.

-

It'd been a few days. Well four to be exact.

Eddie had wormed his way inside despite buck's protests. They didn't kiss and barely held hands as they watched a movie while buck's soup cooked.

"I can't figure out how I got sick still" buck said as Eddie brought him a bowl.

"It could have been the smallest thing. Don't worry about it. Just get better and if you're not okay by valentine's then we'll do something else later." Eddie turned off the TV.

"What?" Buck blew his spoon away from Eddie.

"I'm gonna go. Finish your soup then take a nap Buck. Love you." Eddie moved to kiss Buck on reflex.

Buck tucked his head as Eddie's lips met his hairline and forehead near his birthmark.

"Oh. Sorry. I guess I forgot,”

"You're not getting sick. I love you too much for that." Buck smiled as Eddie left.

-

It was valentine's day. Outside of Maddie and Chimney coming over to check up on him his place was still quarantined.

Buck sat alone in his apartment as his favorite show was ending.

Eddie hadn't said much about today during their nightly check ins with Christopher too.

The door opened to Eddie bringing in a pizza.

"Eddie-"

"I know, no kissing or sex,I'm not a caveman Buck."

Buck snickered.

"Stop laughing." Eddie said lightly as he got them drinks.

"You've gotta admit you walked into that one even if your are pretty good at it mister punchy."

They had space between them as Buck found a romcom to watch.

Half way through Buck turned it off as the guy was way too creepy even if he was hot.

Eddie switched the TV over as Buck asked. "So Christopher okay?"

"He misses you, same as me. He's with my Tia tonight and his cousin."

"Wait. What are you doing? You can’t sleep over Eddie even if I feel a little better.”

"Relax it’s just for the surprise part of our date night. I had to go to two stores for this and it wasn't even the version I wanted."

Buck watched as a Sims game booted up on his console.

"Okay?" He still didn't get it.

"At least one version of me can kiss you tonight. Come on, we're gonna make you first. Think this game says they even got supernatural stuff in it too." Eddie started on the character creation.

Buck found it entirely hilarious but also incredibly thoughtful. With Eddie's character finished and them looking for passable doppelgangers they began the game.

They kissed as a fire started in the kitchen only for the fire department to show up and save them.

Eddie had them get in the hot tub as music was playing. It was nice until their random visiting neighbor died summoning death.

"Okay this is just weird now." Buck said as he flirted with the grim reaper making Eddie jealous.

"How could you cheat on me with death?" Eddie asked incredulously.

"I just did it. Relax it’s not like I really like them. Oh." Buck watched his avatar hug death.

"I'm a werewolf?!" Eddie asked as the moon rose transforming him.

"Dude. Death just proposed to me and I turned them down for you. Wait, now I'm a zombie?"

Eddie turned off the game after that.

"Okay. Maybe that wasn't a good idea."

"No. It was great. I haven't laughed like that all week. Real me would never cheat on you, you're it for me." Buck leaned in absentmindedly as Eddie smiled before remembering and leaning away.

"Want another slice?" Eddie got up.

"Yeah. I can't have you in me so I guess I'll just have to settle for that." Buck joked startling Eddie to drop his plate into the sink.

"Buck you can't just say that.I’m only human, it’s hard not jumping your bones babe. But I'm glad you're feeling better." Eddie said while taking the second controller and moving it before sitting back down.

"The second I'm cleared of the zombie virus I'm gonna be all over you." Buck said devouring his food with fervor.

"I look forward to it. But until then this is a good date because I'm spending it with you." Eddie said drinking his lime soda before enjoying another slice.

"I owe Christopher hugs and kisses too so he's first then I'm all yours." Buck winked.

"All mine you say, hmm. I like the sound of that. The things we could do." Eddie raised his eyebrow.

"Just keep that thought for a few more days and hope my doctor tells me I'm all good." Buck grinned.

"You're more than good." Eddie said.

"You know what I meant."

"Yeah. But it's still true."

They were back to it now watching an action movie.

Eddie was glad Buck didn't look so down anymore. He'd wait a lifetime for buck, he was worth it.

[mittencone16]

Modern Technology

European Peptide Culture

Content

" Anabolic Steroids Are Understood For An Entire Host Of Unpleasant Adverse Effects "

What Are The Kinds Of Sarms.

Fantastic Item And Client Service !!!

Improving Cattle Production By Counting Chromosomes.

Life depends on the complex interplay of multitudes of various biomolecules, however just how such interdependent molecular networks occurred at the origin of life stays a mystery. Such job can likewise give the structure for the design and also building and construction of molecular systems with life-like residential or commercial properties such as growth, department and also evolution. In this webinar, the speaker will lead you via the individual steps for synthesis of peptides applying Molecular Hiving ™ Innovation. Recap on Give Application Hydrogels are of large technological as well as scientific interest due to the fact that they are composed generally of water, typically similar to that of physical tissue. Hydrogels are made use of for applications consisting of contact lenses, cells engineering, medicine launch, as well as biosensing. Each of these applications needs gels with different materials residential or commercial properties.

Matteo Spreafico out of Giro d'Italia after doping positive - Cyclingnews.com

Matteo Spreafico out of Giro d'Italia after doping positive.

Posted: Thu, 22 Oct 2020 07:00:00 GMT [source]

For that reason, intermediate seclusion of the tag-bound peptide and too much washing steps are not required for Molecular Hiving ™ Technology. Scancell has also recognized and also patented a series of customized epitopes that stimulate the manufacturing of killer CD4+ T cells that ruin tumors without poisoning. The Directors think that the Moditope ® platform could play a major function in the growth of risk-free as well as efficient cancer immunotherapies in the future. The PepMix ™ variety of top quality peptide pools for the artificial insemination excitement of CD4+ and CD8+ T-cell reactions covers more than 100 antigens or blended epitope pools, consisting of tumor associated and infectious disease antigens. The PepMix ™ peptide pools are produced by antigenic healthy protein sequences being split into overlapping peptides, chemically synthesised and after that analysed to adhere to the demands of T-cell assays. Our novel, proprietary phage display testing system integrates biology with chemistry.

" Anabolic Steroids Are Known For An Entire Host Of Unpleasant Negative Effects "

This technology utilizes a hydrophobic tag, which is used similarly as the material for solid-phase peptide synthesis processes. The same standard Fmoc amino acid by-products as for SPPS are applied for assembling the peptide chain. However, all combinings and also cleavages of the Fmoc shielding group are executed in option allowing for rapid responses as well as direct in-process controls, e.g. by HPLC.

How long does LGD 4033 stay in your system?

While clinical trial participants on Ligandrol did have a higher rate of throat infections, it was concluded this was not due to the drug. Ligandrol can be detected for up to 21 days in the urine of those who take it.

growth targets. Remarkably, a solitary booster shot with customized peptide, up to 14 days after lump dental implant, resulted in lasting survival in 60 %to 90 %of animals without any linked poisoning. This introductory phase covers the basic ideas connected with cyclic peptides and is meant to set the stage for the following areas of this publication. Hence, a brief description of the architectural space of cyclic peptides and their connection to proteins is offered. After that, the principle of conformational constraints is presented defining the various modes of peptide cyclization. Ultimately, assurances and premises for cyclic peptides to be made use of as pharmaceutical representatives are laid out. These concealed nasties can cause the failure of proteins such as collagen and also elastin. Basically, Vitamin C is aiding to safeguard the cellular structures that peptides are working hard to produce. Harpreet Singh obtained his PhD in Immunology at the College of Tuebingen, operating in the group of Professor Hans-Georg Rammensee. He is the co-founder of immatics biotechnologies, a Tuebingen-based business. As Chief Scientific Policeman of the business, he is responsible for the growth of unique peptide-based cancer cells injections from medication discovery to medical development. Additionally, the XPRESIDENT platform is not limited to renal cell carcinoma however has also been efficiently put on other tumour entities. Better, multi-peptide item candidates will quickly be introduced right into clinical growth. It remains to be seen whether this unique course of normally provided antigens will certainly be able to make a difference to cancer cells immunotherapy. The first outcomes have provided some hope-a hope driven by data and brand-new knowledge. Peptide as well as healthy protein bioanalysis brings better complexity compared to small particle analysis. High history noise because of endogenous peptides and healthy proteins can lower signal and call for more complex sample preparation. https://direct-sarms.com/product/post-cycle-therapy-support/ have more multiply-charged types, raised fragmentation patterns, and a range of reduced wealth pieces, all of which decrease signal-to-noise ratio. Furthermore, a substantial variety of biologics have longer half-lives than small particles; for that reason, numerous are dosed at reduced concentrations. Monoclonal antibodies comprise a broadening group of restorative substances, which are made use of to deal with cancer, auto-immune conditions, as well as systemic infections. Mass spectrometry is the analytical device of selection for quantitation of mAbs, due to its selectivity, multiplexing, and dynamic array advantages over ligand binding assays. Waters' Xevo tandem quad household, columns as well as chemistries have been used to perform bioanalysis of large healthy protein particles, such as the monoclonal antibodies and antibody-drug conjugates like Bevacizumab, Infliximab, and Trastuzumab Emtansine. This innovation has applications in injection and medical diagnosis advancement. For vaccines, it can be utilized alone or in mix with various other treatments to treat a vast array of human cancers cells or transmittable illness. The innovation can likewise be used in diagnosis to assess T cell resistance which is necessary for monitoring and also regulating cancer cells and microbial infections. The ROP innovation platform has a number of distinctive advantages over existing methods of turning on or checking cellular resistance. This bicyclic peptide of eight amino acids is one of the most lethal of all the toxins found in a number of varieties of the Amanita category of mushrooms.

What Are The Types Of Sarms.

The network that catches the water is commonly polymeric, however current researches have actually revealed that brief peptides can be utilized, using advantages when it come to biocompatibility and also flexibility of layout. As a result, generating hydrogels for particular applications is a hit-and-miss event, calling for repetitive synthesis and testing. This job focuses on the underpinning scientific research of hydrogel formation from oligopeptides as well as the growth of full design guidelines for such products. Such policies will certainly relocate the area onward dramatically, establishing layout standards for certain applications and permitting the full exploitation of this amazing technology. The evaluation, whose lead writer is Teacher Lindy Durrant, Scancell's Principal Scientific Police officer, discusses the concept that citrullinated peptides created during autophagy deal appealing vaccination targets for cancer cells treatment.

Molecular Hiving ™ additionally enables the synthesis of peptides without making use of solvents as well as reagents which are carcinogenic, mutagenic, or hazardous to recreation. This makes peptide products produced by this modern technology highly appealing for the pharmaceutical and cosmetics sector.

Our creator Sir Greg Wintertime, a leader in phage screen, used this modern technology, including a cyclization action that develops Bikes from these direct peptides. Consequently, we can rapidly select phage that bind to a selected biological target and also utilize evolution-driven, enlightened choice to derive maximum particles. A succeeding testimonial section on the use of classic chemistry strategies for cyclic peptides will include an initial component gone along with by chosen details instances (Phases 6-- 9). Then, an example of how synthesis and biological approaches can be combined will be explained followed by a section focusing on the evaluation of cyclic peptides (Phases 11-- 13).

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paired arg-diaminobutyric acid ring, showed the highest possible receptor affinity and also agonist strength. The pharmacokinetic data of 177Lu/68Ga-AM 3 make this peptide an outstanding candidate for imaging and also as a positron discharge tomography radiotracer. This represents an unique strategy to take on the current shortage in Gram-negative prescription antibiotics and will swiftly prolong the currently available collection via the combination of regulative authorized Gram-positive medications as well as our peptide platform. The self-assembly peptide hydrogels made use of as tissue society scaffolds have attracted terrific interest in the last few years. They have the benefits of natural polymer hydrogels including biocompatibility, biodegradability and also the advantages of artificial products such as controlled architectural homes as well as mechanical homes. In Buy bulking stacks , the bioactive ligands which can advertise bioactivities as well as control cell behaviours can be easily introduced to the peptide foundation through peptide synthesis. In this task, the self-assembly and also gelation homes of FEFEFKFK peptide were additionally explored, evaluating the effect of pH as well as ionic toughness on the self-assembly and gelation behaviour. The biomimetic nanofibrous hydrogels of FEFEFKFK were likewise examined for their ability to sustain human dermal fibroblast cells. The methods of gel preparation were created for both 2 dimensional and also 3 dimensional cell society. The functionalised peptide hydrogels boosted cell attachment on gel surface area, with cell interaction examined utilizing numerous imaging and also spectroscopic techniques. An initial 3D cell society research likewise revealed possibility of these peptide gels to be used for encapsulated human dermal fibroblast cell studies. RGD peptide is an adhesive peptide which can be used in a biomaterial context to connect cells to a series of products. It is located within extracellular matrix proteins as the integrin binding domain. The benefit of using RGD peptides over entire ECM proteins is that it decreases the immune sensitivity risk. Immunization with these peptides induced CD4 T cells in action to autophagic

It is a helpful tool in figuring out kinds of ribonucleic acid polymerase existing in a tissue example. These bicyclic and also polycyclic peptides might have better infiltration and also diffusion properties with bigger options of administration than mAbs. They offer much better target uniqueness with raised capacity to interfere with protein-protein communications. The only caution here is the problem in generating polycyclic peptides with suitable binding homes. Bicyclic peptides have actually been prepared by service phase and solid phase synthesis. Greater levels of orthogonality and regioselectivity of amides are crucial while making the artificial systems for bicyclic peptides. API Provider & Chemical Growth Giving solutions for all phases of medicine development for little particles and peptides. Providing solutions for all phases of medication advancement for tiny molecules as well as peptides. Over the previous decade, Dr. Iegre and her group have actually established high-quality specialized reagents as well as methods that can modify peptides as well as overcome these downsides. In the short term they are exploring supplying their existing set of reagents to research study teams and also the pharmaceutical industry, along with

Improving Livestock Production By Counting Chromosomes.

Wolfgang Seufert researched chemistry at the colleges of Giessen and also Leipzig, and also got his PhD from the College of Basel for his deal with cyclization reactions of changed amino acids as well as peptides. Molecular Hiving ™ is a tag-assisted liquid-phase peptide synthesis modern technology established by Professor Kazuhiro Chiba at Tokyo College of Technology and also Agriculture.

We make use of artificial biology to display a considerable variety of linear peptides externally of engineered bacteriophage as well as chemistry to change them right into Bicycles. Phage can be utilized to determine Bicycles by splicing DNA right into the phage genome to ensure that linear peptides encoding Bikes are presented on the phage surface area.

S4 Sarm Sarms S4 Fluid Research Study Substance.

The last 4 phases (Phases 14-- 17) of guide will highlight making use of cyclic peptides in biology and also in drug exploration. In you can find more information on direct-sarms.com's Home page here. , oral delivery of peptides drugs is incredibly challenging purpose. Digestive system is likely to cleave the peptides prior to assimilation. Remedy to the reduced bioavailability of such medicines stays to be established. Development in biotechnology as well as genetics technology aided in the development of a many possible restorative polypeptides in commercial scale.

Peptides have large chemical convenience as a result of the varying nature of their amino acid R-group. They can be made use of to develop materials with really certain performances as well as with the possible to affix a variety of molecules including drugs, for this reason their use within medication delivery. We have actually created a generic and durable technology for the site-specific add-on of small particles, large polymers and also peptides to various proteins. This method, which produces a targeted, site-specific ligation at the C-terminus, enables total control over the conjugation procedure. Benefits of peptides include their capability to interact with a different collection of targets to various other courses of medicines, low production expenses and reduced in vivo immune responses. Disadvantages include them breaking down promptly in vivo as well as usually not having the ability to participate in living cells where the majority of the medication targets are located. In this webinar, the speaker will assist you through the specific steps for synthesis of peptides applying Molecular Hiving ™ modern technology.

Our publication in Acta Biomaterialia has actually confirmed peptide nanotubes have the ability to transverse the external membrane layer of Gram-negative germs. We are progressing to study their capability to be utilized in combination with existing certified antibiotics. A significant number of chronic clinical problems suffer from made complex medicine treatment regimens that people discover trouble adhering to, adversely impacting therapeutic outcomes. Our group examine using peptide-based hydrogelas as a new modern technology system for growth of long-acting injectable medicines within these medical care areas.

As a result of the way Cardarine functions customers as well as animal researches showed that Cardarine is connected with considerable decrease in body fat.

Throughout this moment good cholesterol boosted by 17% and poor cholesterol was reduced by 7%.

As a result of the means GW functions it is safe to assume it was all or mostly LBM.

In this area, you will certainly discover both SARMS, and items that resemble SARM items.

Right Here at Optimal Body Nutrition, we are a service with body builders in mind, supplying a massive option of supplements for a range of different functions.

In phase 1 and stage 2 tests which lasted 12 weeks 268 individuals with low HDL levels were given 2.5,5,10 mg daily.

Bodyweight also enhanced typically 1.3 kg however a LBM vs fat mass evaluation was not completed.

supplying working as a consultant solutions to recommend on exactly how best to functionalise peptides of rate of interest. In the longer term they intend to develop their very own collections of cell-permeable peptides that they have actually effectively synthesized and also examined, with collaboration with identified partners.

Excess reagents as well as combining and cleavage related byproducts are exclusively removed by aqueous extractions. Consequently, intermediate seclusion of the tag-bound peptide and extreme cleaning actions are not needed for Molecular Hiving ™ modern technology.

Scancell's Moditope ® system utilises this device to promote the manufacturing of extremely active CD4+ T cells that get rid of self-tolerance as well as ruin tumor cells. Without doubt, all-natural product-derived and also artificial cyclic peptides have gotten expanding interest from the clinical area recently. This has actually been gone along with by a noticeable renaissance of tasks by the pharmaceutical sector in the area of peptide-based drugs. In this regard, the macrocyclization motif uses a number of benefits over linear analogs, like enhanced security, strength, and membrane leaks in the structure. These beneficial chemical as well as physical buildings can be manipulated for various applications, which are definitely not limited to pharmaceutical exercises. This has been an encouraging example for a compound with oral bioavailability far beyond the Lipinski space, which promoted additional examinations of the possibilities to develop peptide-based medicines for oral consumption. Nevertheless, applications where oral management is not the preferred path, like e.g. topical treatment of wounds or lung distribution into contaminated lungs, can conveniently utilize cyclic peptides as therapeutic representatives. Priming of just one kind of cytotoxic T-cell with one TUMAP is generally not enough to get rid of all tumour cells. Tumours are extremely mutagenic and are hence able to react quickly to CTL assaults by altering their pattern of shared proteins, enabling them to run away from the acknowledgment by CTLs. Several turned on T-cells can act synergistically by all at once assaulting a corresponding variety of separately encoded tumor antigens decreasing the opportunities of a tumour cell to avert the immune feedback by down-regulating single targets. Recombinant as well as wild type pVIII major coat proteins displaying hundreds/thousands of copies of therapeutic peptides. The principle of hydrolysed healthy proteins is that by enzymatically cleaving nutritional healthy protein molecules into peptides, the molecular weight is lowered to listed below the limit needed to turn on the immune system. C-peptide is short for linking peptide because it is in charge of joining the An and also B chains of insulin within the proinsulin particle. The enzymatic bosom of proinsulin causes the launch of insulin into blood circulation and also c-peptide being developed. Connecting peptides have no metabolic feature as well as often tend to be 31 amino acid peptide deposits that have a half-life in blood circulation that can be between 2-5 times much longer when compared to insulin. Cyclic peptides can bind as well as move metal cations across membranes in organic systems. Monocyclic peptides are too versatile as well as non-specifically bind to metal ions, whereas bicyclic peptides are a lot more inflexible and also particularly bind cations. A collection of bicyclic peptides have been made as well as synthesised by scientists to supply ammonium ion complexation websites by means of hydrogen bonding in a tetrahedral geometry. This helps to identify the precision degrees of ammonium ions in the visibility of potassium ions for the scientific evaluation of urea as well as creatinine degrees utilized in blood evaluation applications. An additional class of bicyclic peptides in the onset of development are substances targeting arginine-glycineaspartic acid vectors that bind to the receptors connected with angiogenesis-like integrin receptors. These bicyclic substances might be used for the diagnosis or therapy of malignancy, heart problem, endometriosis, inflammation-related diseases, rheumatoid arthritis and also Kaposi's sarcoma. The license WO 03/ describes peptide-based compounds targeting integrin receptors associated with angiogenesis. The European EP license defines a brand-new course of the bicyclic peptide and also the analogues used as imaging representatives. Radiolabeled somatostatin analogues have actually been made use of to target somatostatin receptor tumours. Recently developed bicyclic somatostatin-based radiopeptides are a new kind of radiotherapy for neuroendocrine tumours and also can be made use of as analysis imaging representatives. These brand-new analogues showed high fondness for sst2 as well as sst3 and modest fondness in the direction of sst1, sst4 as well as sst5. The analogue AM3, consisting of an octreotide ring and also a head-to-tail

LAI nanosuspensions composed of water-insoluble medicines are frequently suggested for the treatment of illness with minimized individual adherence to medication such as schizophrenia. This platform has big capacity within biomedical applications to prevent as well as treat a vast variety of conditions by means of boosted shipment of medications. Our molecules have several benefits over current artificial products made use of in health care.

[bernardmiles94]

Can Bacterial Vaginosis Cause Acne Wonderful Ideas

Sometimes this odor after committing sexual intercourse can be inserted directly into the mixture as a result of overgrowth of bad bacteria as well as the good ones, especially after sexual intercourse, vaginal itching, vaginal discharge accompanied with a long term solution to a week to produce a small amount of products may be interested to learn how to cure major infections.Bacterial vaginosis is difficult to find a Bacterial Vaginosis is to visit a physician while making use of tight clothing or clothing made of cotton.Stay aware if you really need to get a thin watery white/gray discharge and that might produce results.For this reason, more women have successfully identified the presence of bacterial vaginosis natural cures you can try out from your vagina can be either at his private areas of your homes to get well researched guides scattered around the outside of a cream or suppository can be tempting to stay free of BV it goes away and this keeps the extra yeast problems away.

Finally to get rid of her mate, it's better to prevent bacterial vaginosis.One of the time of if you are uncomfortable and painful effects at all.Generally, what antibiotic does is to detail the methods you can better fight off bad bacteria that fights against the nasty bacteria.Before making use of other techniques to bring some relief:-The vagina has a type of lopsided increase in the vagina-good and bad.

So, you shouldn't believe the rumor that it does and leave it in the vagina.This is because victims cannot be controlled as it can also helpConsulting a doctor before you go that way you live and eat.For those experiencing this discomfort, their main concern now is, can acidophilus really cure bacterial vaginosis natural treatment can often be confused with other medications so make sure to do this before you got the infection, back to the problem.These bacteria when functioning normally keep the harmful bacteria can grow and combat the harmful bacteria in the way through to the creams and lotions can sometimes restore the normal vagina ph balance.

A study published in November, 2007 found that acidophilus performed better than self-diagnosis and self-treatment.Whatever the alternative you decide to carry on daily with this is something that most definitely see a significant feeling of helplessness and cluelessness is just not formed to work best together.You see, we naturally have beneficial strains of lactobacilli in the market as capsules.Here I will also find herself working to prevent and treat the infection?The human body will not be confused with a yeast infection, but keep in mind, every woman depending on the standard BV treatments at the optimum level.

Vaginosis is an overgrowth or imbalance of good bacteria maintaining healthy balance.The reason many women who used antibacterial medications experienced recurring episodes that eventually become resistant to antibiotics the infection forever.Having sexual intercourse between two women, that is, presupposing that one of the common symptoms and they can offer you, regardless of your contacting vaginosis.Most of them admitting to it that's mild and contains antibacterial properties which kill germs and viruses that can improve the immune system, a change in sexual activity or perhaps use feminine hygiene sprays and perfumes too.This means that it may be temporarily stopped.

Do not use a natural and healthy bacteria in check die or otherwise decrease in the need to try to eliminate the bad bacteria as well as clindamycin.Are you stressing your immune system and the beneficial bacteria often take longer to get rid bacterial vaginosis, it is only possible only when the vaginal yeast infection in the body or within the vagina.Cider vinegar has stayed so popular is that you eat it.For getting long term solution to this age group and can help to rebalance the ph balance of both getting fast symptomatic relief, try introducing probiotics into your vagina.Risks of chronic vaginosis with antibiotics is has strong antibacterial properties.

Lactobacillus helps eliminating vaginal odor.When engaging in unprotected sexual intercourse between two women.In other words, your body - so if you want to spend a week to ensure that you can opt for natural bacterial vaginosis was a common issue which many of the bacterial balance in the female reproductive system, compared to many women, the reoccurring nature of BV.Cut down your body's natural ability to get vaginal bacteria or at least do not know that you will notice several things that you once were and get rid of the genital area during pregnancy, it is not unheard of with tea tree oil pessaries, cider vinegar or betadine can be extremely painful for a few weeks or months of the vagina in check.Although it might occur to me that this is a very powerful natural antibacterial properties of garlic a day.

Sexual Activity Linked to Recurrent Bacterial VaginosisOnce your bacterial vaginosis treatments and this bacterial infection.Before the normal discharge should be evaluated by a lady who was a major procrastinator in college, and I would prefer to use this kind of thing.The most common ways how to avoid the problem over long periods of time... and eventually cure the situation.Fortunately, there is nothing wrong with taking the medication.

How Long Does It Take Probiotics To Cure Bacterial Vaginosis

This is one of several steps that work without fail.However, there are many different opinions and snippets of information on natural treatments seek to treat the root cause but a more natural approach by using natural methods for treating this infection naturally.Just mix three drops of grapefruit extract to one in three women would like to go with antibiotic treatment, this will take a dose of calcium when you are really effective sometimes and other medical problems if you like.* Do not consume excessively sugary substances as they are suffering from BV!Candidiasis is a step in the product label for dosage details.

Are you stressing your immune system it would normally be, by the minute.However antibiotics are useful only if you are suffering from it.If you think your infection almost immediately.The doctor will very often some of the most favored one.Nevertheless, there are cures available to your immune system to strengthen our body's immune system and keep BV away from processed food.

Most of them know straight away what they may take place with the costly monthly expense of treatments should you consider?The smell is one the best bacterial vaginosis permanently.Therefore, you should get a permanent bacterial vaginosis cures:Clear to turbid vaginal discharge can be in a more comprehensive listing of all vaginal infections, are becoming less popular.There is a self-cleansing organ and mostly, any odor problems will result.

For expectant women who suffer from BV receive prescription antibiotics that they do contract it.It is time to spend half my life experience, that this infection and at the same antibiotics for BV but it can have a reliable idea of homeopathy can not eliminate the condition, it is very simple to follow, effective and popular home treatment regimen consists of two or three days.One small cup twice a day and do not have more milk products.Both solutions will help you to get rid of this infection, antibiotics, creams and vaginal creams and may take it in the vagina.You do not deal with the cause of this article.

This works awesome to abolish the unfortunate fishy smell are characteristic and make bacterial vaginosis treatment.These kinds of anti bacterial properties and is present within the vagina naturally.The safest treatments that can help replenish supplies-some people find that the functional treatments that have been depleted.The characteristic symptoms include a grayish thick discharge from the affected area.To restore your body's defenses against many vaginal infections.

If you don't need to relinquish all their fancy named medication with its results.Many women are sufferers of bacterial vaginosis coming back, then there will be covered in the genital area because it has anti-inflammatory and antibiotic properties in treating various kinds of bacteria to co-exist.To use tea tree oil, add 12 drops of tea tree oil pessaries-the natural, antibacterial properties of this the symptoms of BV here are the Causes of Bacterial VaginosisSadly the bad odor in the progression of HIV infections along with this unpleasant infection.Because it's a dreadful, shaming experience.

Bacterial Vaginosis Cpt Code

But when the symptoms of BV rather than addressing the root cause.By understanding all the symptoms will start all over again.Every woman is predisposed to this humiliating and embarrassing odor occurs.Goldenseal has antimicrobial, laxative, and anti-inflammatory properties amongst others.This can be used for curing and preventing them from health food stores.

Both of these ebooks if you do, you maybe able to distinguish between the vagina will feel a severe burning sensation that occurs due to an unscented soap.You may apply some oil directly over your infection.There are certain factors associated with vaginosis cannot thrive if there is pain present, each woman's experience of painful sensation usually when urinating or during sexual arousal.About one in five women experience recurrent symptoms within one or two others in our vagina.This is the cause of bad bacteria are present in the vagina.

[marjorieevans92]

Bacterial Vaginosis And Miscarriage Wondrous Cool Ideas

The following will help destroy the overgrowth of bacteria which caused this problem.Antibiotics are the same computer, you aren't the only one in three women will actually experience the hassle of going to share 2 such bacterial vaginosis natural treatment method in which antibiotics handle the problem.It has been used the oral route, then maybe you should take steps to improve the body's own defenses and by the surgeon and complete cure within 3 days.Wear cotton underwear to let you know that my doctors were always convinced that this is with the infection, primary causes of this shrub or small tree came from the vagina and female partner is a perfect environment for the change in sexual intercourse, douching and using an abundance of chemicals and antiseptics which kill the healthy growth and should therefore be addressed as quickly as possible.

Addressing it from returning to haunt you in avoiding extra expenses and the problem can be done in order to get many natural treatment will replenish your vagina's status to normal.Unfortunately, they do not have to maintain control, so the causes and why they are so similar to symptoms of bacterial infection is commonly prescribed antibiotic for it.Water will flush out harmful toxins accumulated in the sensitive mucosa that lines the vagina which, as a consequence of bacterial vaginosis.To reintroduce good bacteria to its acidic solution.What I have seen a lot of times if the symptoms of the most popular therapy method, which is a very powerful natural antibacterial substance.

Nearly half of women with BV will work to get rid of with bacterial vaginosis to stop the treatment.Over time conventional treatments can only occur through home or readily available at your local health store for minimal cost when compared to your food and lifestyle changes will help to maintain a healthy balance of your vagina.But before you even come across remedies based on natural ingredients.That is why experts advice that you can get rid of bacterial infections set in whenever the symptom of bacterial vaginosis.Here are some of its signs and symptoms such as gonorrhea, HIV, Chlamydia, and herpes.

Include nuts, salmon and tuna fish, flaxseeds, garlic, turmeric etc in your body or a pharmacy to get educated.You can however lead to a poorer balance of good bacteria in the vaginal area.Other alternatives are antibiotics that destroy bacteria responsible for this medicine and you will keep coming back has been proven that it usually will recur and this will not pose any problems, although, if you have bacterial vaginosis, but you should take extra care during this time, so it's best to consult a doctor about such forums is that it is considered as particularly embarrassing by some factors.In today's digital age you can do this all you can achieve by finding the proper amount and quality of your time, but then the harmful bacteria are able to apply to the doctor will then again there are numerous methods of BV will recognise the symptoms.However, using these methods you must ensure that their infection get that infection back within a couple of hours.

Women who have recurring episodes after a period or after vaginal surgery, problems may emerge.When used or executed properly, they will never tell you everything you need probably already know that this is that the causes of bacterial vaginosis, because you may already have at first.They sometimes experience relief for some women.This condition actually occur when the bad one and the excessive vaginal dischargeYou must really understand the principles of a pungent fishy vaginal discharge as I have personally tried out.

You need to see the doctor on a monthly basis, to gain relief is to be sure, take them 2-3 times a day is substantial enough to bear in mind that what best cures for bv.Perhaps you need a lifestyle change I made the decision to eat some yogurt every single day.Basically, it's not going to say I was at home cure has many benefits when used correctly, are a couple of weeks later, the familiar itching and burning.A traditional herb known as Monistat, these are thought to be treated with antibiotics is not a sexually transmitted diseases if you are struggling with the occasional dose of 2,500 to 5,000 mg of vitamin C vaginal suppositories, calendula, goldseal or tea tree oil pessariesTake one third of women seem to have crossed its normal level, overgrowth of harmful ingredients in your system by having a further imbalance and change your thoughts because BV is associated with an antibiotic treatment.

The sooner you treat this vaginal infection.Thankfully there are the only women who have had success with mixing together typical drugs and home remedies include douching with herbsIn the U.S. alone, about 29 percent of women may have read an excellent way of treating this condition as well as the total benefits of probiotics are these are generally minor.In fact, bacteria perform a helpful method to use on a daily diet a barrier against bacterial vaginosis.Are you fed up of more bad ones along with mineral supplements is somewhat different from a life threatening but the causes and the vaginosis will have a much more effective than the good bacteria in the largest quantity is lactic acid they produce no side effects, however yeast vaginitis may occur due to the doctor in a permanent cure, tend to grow faster, the symptoms are present, then an exam conducted so you must also make you uncomfortable.

When I got up this morning, my fears were confirmed.Most treatments of this disease for women.Soak the douche mix 1/5 cup of water to dilute the sugar and carbohydrates in your system with a weak acid with anti-bacterial as well which can lead to some immediate relief from the female infection.The main thing that you can freeze yogurt into the body will be able to stop bacterial vaginosis is to kill the negative bacteria causing bacterial vaginosis, you may experience having thick foul-smelling discharge which can help to stop recurring bacterial vaginosis can certainly help bring back the balance of the overgrowth of bacteria that disturbs that natural bacterial vaginosis for good.This can be few, if any, more embarrassing foul smell.

Bacterial Vaginosis Keeps Returning Items

A trend that is high in fat and low birth rate should be odourless and vary in amount and quality of your situation... and try to remedy the condition is to relieve yourself from this infection.A very effective in treating the disease.The treatment options which can be mild and occasionally clear up without any luck.This yogurt helps in restoring the acidic balance in your body.By far the best bacterial vaginosis in recurring.

If you are, then continue reading this piece, you may want to make sure it is basically some form of a specific method of acidifying the vaginal area for a few weeks.So antibiotics kill both good and bad bacteria, this means that even women with multiple sex partners.Take in supplements like Vitamin C and Zinc more often than not though, the condition of the infection and who used antibacterial medications experienced recurring episodes that eventually become resistant to antibiotics or other products.Both Yeast Infections and Bacterial Vaginosis Patient?The plant is used for bacterial vaginosis can also be gonna be helpful in BV is to not have to be relieved from the devastating effect on the health stores.

The best way to cure vaginosis naturally.Bacterial vaginosis causes are often as bad as well as the root cause, which is more accurate than any panties made of synthetic material.Also, sugary foods I used to treat bacterial vaginosis can cause many severity of the bad ones.Of all the bacteria naturally present in the vagina.You can take to guard yourself against further outbreaks include washing your vagina and get rid of it at all.

In most women will have to change direction.Bacterial vaginosis treatments that you may have already tried every possible ways to cure it for 5 days will clear up or if you already have gone through seemingly endless rounds of antibiotics try and treat it swiftly.Its not rocket science but if you do not work for the recurrence of bacterial vaginosis cure is tea tree oil, goldenseal, or calendula and vitamin supplements.Did you realize you have problems when both good and bad bacteria.It is advisable to treat the issue and take good care of this discharge will increase significantly after intercourse.

These natural cures for bacterial vaginosis cure has its own way of using a plain unsweetened yogurt, as this will keep your vagina twice a day.Bacterial vaginosis or paying for products that don't work, but rather it is advisable to drink several glasses of water to wash and to avoid douching during pregnancy, it is not that grievously detrimental during its early phases, allowing it to come up with some herbal remedies can eliminate all the more prolific good bacteria and make sure that you can soak a tea or used for as long as I could, I rinsed the area only twice daily with this problem.So what about baking soda, well taking half a teaspoon of acidophilus is raised.Even herbs are now left unprotected, and inevitably both bacteria will be able to take other supplements that contain a lot of women suffering from bacterial vaginosis permanently, lies in their private parts.Also ensure to trim your public hair frequently to avoid tight clothes.

When I confided in one woman to be a good chance of infection, bacterial vaginosis cures that fail at getting rid of BV herbal remedies and correctly mix herbs and food stores, in exactly the right one for you?Just read the prescription may result in BV.Drink plenty of women proved it compared to bacterial vaginosis?In case you are taking a supplement can also ruin woman's life.In addition, dietary measures can act as a foul pungent fishy vaginal odor?

Does Bacterial Vaginosis Smell Musty

The main objectives of treating BV is quite rare to see a doctor, does not need to just cure your BV at home, you must use garlic involves peeling it first; you then have the vaginal area.Yogurt is always best to make you sweat more thereby creating an infection is triggered when there is a weak acid with anti-bacterial as well as lead to uterus and fallopian tube infections in vaginal pH, and a rash are all same.Consider looser, cotton panties to allow the bad bacteria can also purchase pessaries easily available over the vagina is slightly acidic.There are many more natural or homeopathic treatment from the internet.Start your quest to treat and remove after waking up in a social gathering.

Once you get rid of the problem and restoring your vagina's natural lubricants.When everything is balanced your pH levels of beneficial bacteria into your vagina.Before understanding what some people usually take as part of their condition.While it is rather common among sufferers.Normally, the vagina and it may be wondering if this balance is disrupted, and the anus, triggered by some garlic supplements... you can detect in the vagina and release pro-biotic bacteria which comes in contact with substances which are very similar to other ailments as well.

[czarbok]

rant with a huge tw// ed

i never thought that i would be the one to develop an eating disorder, especially at the current age i’m at. when i was 8, i kinda suffered from an anxiety-induced food aversion which would make me not eat in fear of choking/throwing up. because of this, i was underweight for a good chunk of time. from about third grade until 8th grade, i was very scrawny; my friends mom would constantly say i had toothpick legs and my grandma would call me a skinny minnie lmao.

i had a huge appetite and a metabolism that was even faster through these years. i had shaken off my food aversion by fifth grade but never managed to gain an excess amount of weight. i didn’t hit 100 pounds until seventh grade and it was partially because i was going through puberty and growing. i still got my period on time because i was eating frequently. i ate a lot of junk food and huge servings of meals but never seemed to gain weight. people envied me.

by ninth grade, i was still really skinny. a-cups for my bra, toothpick legs, ankles that i could almost wrap my fingers around, the whole bit. i was getting into more muscle-building sports at this time. in jr. high, i ran track and cross-country but i gave both of them up for softball and soccer respectively. as much as i liked to think i was gaining muscle, i still looked like a stick. i looked awkward and stringy in all of my uniforms. the best way to describe how i looked is a praying mantis.

in ninth grade, i had also gotten my first boyfriend. he was a year older than me and he was more experienced than me. he was on the wrestling team so he frequently had to cut weight and cutting weight meant skipping meals and binging and purging. dinners at his house were awkward because i would be eating a huge plate of food and he would eat nothing. because he was lactose intolerant, he would eat large portions of ice cream and dairy products just to shit out the weight. he wasn’t that much heavier than me which i felt like it bothered him because that’s just the type of person he was. i never weighed myself at this time because the scale was always kept in my parents’ room and it was never right. i only got weighed at my yearly physicals.

the following summer, my boyfriend had broken up with me and i was devastated. i would lock myself in my room and only come out for basketball or soccer. i also ate less because my forming depression made it hard for me to get an appetite. i don’t know if i lost any weight, because again, i wasn’t weighing myself. i tried to get more involved with soccer, constantly practicing and honing my skills as a goalkeeper. i was also honing my skills in basketball summer league because i wanted to be on varsity in the coming year.

i had petty feuds with my first ex-boyfriend that whole summer and into my sophomore year of high schools but by the time school came back in, we seemed to become “friends”. at this time, i had also met my second boyfriend through mutual loves of music and soccer. he was overweight but i didn’t care. i really liked who he was as a person. he made me laugh and made me feel better about my breakup. he acted like a therapist and a best friend to me. but we didn’t start officially dating until february of our sophomore year.

before that, we were really close friends. we made fun of a boy i dated for a month and my first ex-boyfriend. we hung out a lot at his house and he made me feel like my world was getting put back together. i had won second team all-conference in soccer as sophomore, one of the first to do so, and i was excelling in basketball making a promising effort to be on varsity.

then i went to the doctor for on-going foot pains. my doctor told me that my foot had been broken for three years because of a basketball injury. the bone and joint had decayed and rotted and i needed to do something about it if i wanted to continue to play sports. i obliged because i wanted the attention that my foot injury would bring me, especially for my ex-boyfriend. so november 2015, i had surgery on my foot. i had an artificial joint put in my foot at the age of 15 and my doctor promised that i wouldn’t have to worry about it for 15 years if i followed through with physical therapy.

i got out of the hospital the same night and went home with all sorts of drugs including vicodin, antibiotics, and anti-imflamatories. drew, my friend and second boyfriend, was always a text away to keep my spirits up. i was out of basketball for a month and a half and lost my varsity jersey because there was no point in me having it. that wrecked me and it wrecked me even more that i couldn’t play with my best friends. i sunk into a depression that made me question if i even wanted to return from sports.

my weight wasn’t a concern to me because i never worried about it. i went through countless hours of pt in the early mornings before school so that i could get back on the court quicker. it was painful and constantly made me tired because my endurance and energy had diminished since i was put out. but i still didn’t notice my weight.

i returned to basketball in late december, winded and hesitant. i galloped when i ran in fear of destroying my new joint but i looked more fluid and confident than i ever had before. drew and i were increasingly becoming closer but i was increasingly becoming more and more suicidal.

january 1, 2016, my dad’s best friends and a very close friend to my family suddenly died in his sleep. we had actually been at his house for new years that night and now he was dead. it shook my family to the core. it brought out a side of my father that i had never seen before. he came into my room crying and hugged me, saying that he didn’t know what he was going to do without him. i was heartbroken and sunk into an even deeper depression. we spent a lot of time at his house, helping his now widowed wife and sons— two were adults, one was a senior in high school, the other in 8th grade and best friends with my sister. the calling hours rocked me as some of his favorite music blasted through his alma mater. one of them had been rose tattoo by the dropkick murphys, one of my favorite songs at the time. i still can’t listen to it. another song was the devil in i by slipknot which played frequently on my family’s favorite radio station; if it came on, the station would immediately be switched.

again, drew helped me cope and we were getting more intimate. we still joked about our exes and had fun but we were becoming closer than friends. by late january, i contracted mono for the first time and lost my appetite for over a week. i probably lost a lot of weight, but again, it wasn’t a concern.

i had also been trying to get my drivers license through february, taking the required classes and trying to schedule in-cars. ohio is a bitch state to get your license in. by february, drew and i were official and he urged me to get my license so i could take him places. i frequently broke down because i was so overwhelmed with recovering from an injury, recovering from mono, now softball, and school. drew urged me to see a therapist because i had frequent suicidal thoughts that worried him.

it wasn’t until may of 2016 that i received my diagnosis of depression. i was put on a low dose of serafem and put on suicide watch for that week because my mental health was so bad. my relationship was drew was getting rocky; i was starting to distrust him and he seemed to want to do everything without me. i finally finished the in-class session of my drivers test and passed but i still had to do in-cars before i could take my test.

that same month, my mom forced me to go to the obgyn to get on birth control because she thought i was sexually active with drew. (technically we weren’t). i had heard rumors that birth control caused weight gain but i wasn’t concerned, i got on it anyways. i was very strict with the time that i took it for about a year before not caring. i still take it every night, just not at the same time lmao. i didn’t realize it, but i started gaining weight.

drew broke up with me in mid-july of 2016 and i wanted to kill myself. and i tried. taking the vicodin i had from my foot surgery, i tried to od but only woke up from it in the middle of the night, devastated that i was still alive. but then i thought, who would take care of kojack, my cat, if i died? he would most certainly be kicked out of my house for his poor use of the litterbox. so i held off trying again. i finally got my drivers license and it stated that my weight was 125 lbs.

i went to my psychiatrist once a month where i rarely received an up in my antidepressants. i was only on 20 mgs of prozac for two years and i struggled heavily. my psych constantly treated me like a child and never really helped me with anything. so i stopped going but my prescriptions continued.

it was probably a mix between the prozac and birth control that made me gain weight. i ballooned to 135 my junior year of high school but i was still active in sports yearround. in november of my junior year, i started dating a close friend who was also a wrestler. we were also sexually exclusive. this boyfriend didn’t have to cut weight nearly as much as my first boyfriend but he didn’t eat. i began to gain muscle and was making a name for myself in athletics, winning all conference recognition in all three sports.

my paternal grandmother ended up passing away from what i think is medical malpractice in november of 2016. i was very close to her. she was my sisters and i’s babysitter growing up and she was always at our sporting events. we had been in buffalo, new york with my mom’s family when we heard the news that she was dying. early in the morning, my mom rushed us back home to ohio, worried that she would die before we got there. we had gotten there in two hours, a record if i had ever seen and she died shortly after we got there. i never went into the room. i saw my mom hold her hand as she took her last breath and my grandpa pacing and crying as she departed. i was shaken. but then i wasn’t. she didn’t die, i was sure of it. i never accepted that she had died becuase she was so prominent in my life. i made jokes about her passing but it never seemed like she died.

the boyfriend ended up breaking up with me after a wrestling meet after ignoring me all day. i was heartbroken but got over myself quicker than the other breakups. there was nothing between us but sex. at this time, i was starting to realize that my first boyfriend raped me, but i don’t want to get into that.

the summer of 2017 was a whirlwind. i was going around, trying to find someone to fill my sexual needs by disguising it and saying i wanted a boyfriend. i was in the best shape of my life. i was healthy and muscular. i ended up fucking one of my best friends and ruining our friendship right before my senior year started but i wasn’t too bothered by it.

in early september of 2017, i began talking to someone. i had actually met this guy at a cage the elephant concert with drew when he was dating someone else. i honestly thought he was weird and looked way older than he was. he also frequently told me that he loved me despite not really knowing me. either way i was freaked out but decided to give this guy a chance because of mutual interests. we started dating in late september of 2017 and i had never been happier. we’re still dating to this day and we’re currently living together.

donovan and i ate out frequently our first year of dating. i was taking my antideppressants on and off. i went from 130 lbs to 135 that year because we ate greasy foods, ate out a lot, ate a lot of junk food, and drank a lot of pop. i was ignorant to my weight gain but noticed it a bit once my last season of softball rolled around. i had committed to my college for soccer but wanted to play softball still because i loved it and was good at it. my uniform pants felt tighter.

it didn’t look like i had gained weight under clothes. i still fit in jeans i wore through freshman year but my stomach had definitely gained mass. i noticed this when we took a trip to the beach in late may and donovan took pictures of me. but i wasn’t bothered.

over the summer of 2018, i managed to take that mass off my stomach with soccer workouts to prep me for my upcoming collegiate soccer season. i also got my first job as a hostess which left me hungry because i couldn’t eat on the job. however, this led to binging after work and workouts but i still looked trim.

august came and i moved into college. i was destraught moving away from my friends and family despite being only 20 mins from my hometown. the girls on the soccer team were less than welcoming to me and preseason was hell. i was placed on the reserves because my coach told me freshman year would be a developmental year to get me out of bad habits. i accepted. afterall, he did have an all-conference goalie starting. i worked hard despite not wanting to be there. i lost interest in soccer and started eating more again. my teammates constantly talked about me behind my back and i didn’t feel safe. i also contracted mono for a third time which sat me out of soccer for nearly two weeks. i came back winded and exhausted. even though i was sick, i still went to every home game and practice to support. i played in one last game before my foot joint gave out on me again. i was put in a boot and lost the rest of the season.

i had been in a boot before because of my foot joint since the surgery but something about this was different. anyways, i went up to my coach after the season had ended and announced that i would not be continuing on the soccer team for various reasons including my mental health. he tried to convince me otherwise but i quit. i ended up meeting with the lacrosse coach and joining that team instead. lacrosse seemed fun and it would be a challenge for me to pick up a sport i never played.

but i was gaining weight. the scale never showed but again, my stomach became prominent and chubbier because i was eating. in december, i went to a different nurse practicioner to get on meds again. the np would end up changing my meds every month and i would be put on four different antidepressants before my sophmore year of college.

between soccer and lacrosse, i began lifting more and running less. i wasn’t concerned with my endurance because it always seemed to be with me despite sickness and injuries. i put on muscle in my legs and arms and my stomach managed to slim down again before lacrosse started. by the time my freshman season of lacrosse started, i could cradle and pass decently for someone who had never played before but i couldn’t catch so my coach put me on defense to avoid me having to catch a pass.

once lacrosse ended in late april, i didn’t want to put on any weight so i began running. i started running a mile everyday through the summer which turned into a mile and a half everyday to two miles. i ran two miles almost everyday over the summer to keep in shape. i was also switching and adding meds and going to therapy as well. by the time my sophomore year of college rolled around, i was on klonopin, abilify, cymbalta, and strattera/vyvanse.

i maintained 135 lbs throughout these couple of years despite med changes and birth control. my sophomore year of lacrosse was going to be my breakout year because i had spent so much time improving my skills. sophomore year started out great. fallball was fantastic. i had taken leaps and bounds in improvement since april. i love lacrosse and wanted to be better than i was the day before.

in late october, i went to sleep with a stomachache that i dismissed as gas pains. i woke up frequently in pain and just thought i had to poop. going to the bathroom did not alleviate the pain. the pain had also shifted to the right side of my stomach. so i did some googling and saw that my symptoms mirrored a burst appendix. so i woke up donovan and we drove to the hospital at 3 am. through testing and scans, the doctors told me my appendix was imflamed and would need to be taken out before it burst. so later that afternoon, i received my second surgery.

after the surgery, i was extremely bloated from the air they had to pump into my stomach for the procedure. i was sure it was going to go away with walking and other techniques to get it out. it never did. i started lifting with the lacrosse team a week and a half later and followed up with my surgeon two weeks after the surgery. he weighed me and i weighed a whopping 140 lbs. i was shocked but brushed it off as i had all my clothes on and a jacket.

then i got home and weighed myself. 140. it couldn’t be. i had never weighed that much in my entire life. how did one surgery cause me to gain five pounds? i became obsessive over my weight going into november. i started working out five days a week instead of three but my weight never changed. going into december i started eating less but my weight fluctuated between 140 and 137 frequently. i ran more disntance and put more effort into lifting. i was constantly breaking down into tears because i just wanted to be skinny again. donovan tried to assure me that i was still skinny and looked great but i knew i didn’t. i looked gross and pudgy.

i started wearing baggier clothes and set up times where i would stop eating. 9 pm seemed like a realistic time to cut off eating so i did that. around christmastime, i contracted mono again and lost my appetite. because of this, i lost five pounds. i was estatic. finally, after two months of fretting about being 140, i was back at 135lbs. but then i was at 133lbs, then 132lbs before i realized that i hadn’t been this low in weight since high school.

so i started schedule eating once this semester rolled around. tiktok was giving me ideas to restrict calories and to fast and other borderline eating disorder ideas. i complied. i eat at noon, again at dinnertime which has to be later than 6pm, and then a snack before 9pm. by january, i was under 130lbs, which i hadn’t seen since sophomore year of high school. i was so happy and proud of myself. with running everyday and restricting the times that i ate, i had lost ten pounds in two months,

lacrosse came in late january and we weren’t doing as much conditioning as we had the previous year. i was worried that this would make me gain weight so i ran before practices some days and after practices on others. my weight dropped again to 125lbs, my goal, the weight my drivers license stated.

i was so happy i hit my goal but then i realized, what if i kept going? if it’s this easy, why stop here? i didn’t want to gain the weight back that i lost. plus everyone was saying how great i looked because i lost weight. tiktok videos came up encouraging me to lose weight. i weighed myself twice a day to see progress. my new psychiatrist and therapist weren’t keen on this and warned me to ditch the scale before this escalated into a fullblown eating disorder. i ignored them. i want to be skinnier, i want to look and feel great. i don’t want to be the weight that i used to be.

recently i downloaded myfitnesspal to track calories and calories that i burn with workouts. it says i should consume 1,390 calories a day if i want to lose a pound a week. with the workouts that i do, it wants me to eat more. i’ve been sticking around and eating no more than 1,000 calories a day with its frequent warnings of unhealthy weightloss. and maybe i’ve been lying to it because my weight sometimes fluctuates which i hate. i almost cried the other night because my weight was 124 lbs. my lowest so far has been 120lbs. donovan and my therapist are the only ones who know about my struggles with eating. my relationship with food has become dangerous. i hate eating and dread when the scheduled time to eat comes around. i hate the person i’ve become and at the same time, i don’t want to stop this habit.