#grapefruit writes
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macgyvermedical · 3 months ago
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I encountered a drug called "Dextromethorphan" when looking up things that react with grapefruits for a fic. I found out it's been banned in Sweden since the 90s, so I couldn't use it for this specific story, but if you've got any interesting history I'd be happy so know!
Are you ready for this? Like. Ask yourself. Are you really ready for this?
In 1954, a researcher with the US Public Health Service received $282,215 (1954 dollars) from the US Navy, ostensibly to find a non-addictive alternative to an opiate drug called codeine (used for pain and and as a cough suppressant).
So the researcher found a bunch of people who had substance abuse disorder and tested 800 substances on them, trying to find ones that couldn't cause physical or psychological dependence, even on people who were prone to that sort of thing.
(Now, you might be asking if this experiment was ethical. The USPHS was concurrently doing the infamous Tuskegee Syphilis Study, so while I couldn't find any concrete answer, imma guess no.)
Out of these 800 tested substances, we use 3 today: propoxyphene (used as a painkiller), diphenoxylate (used as a diarrhea medication), and dextromethophan (a cough suppressant (and, as of 2022, part of a fast-acting antidepressant)).
Importantly, it was later noted that all of these are addictive substances and today most of them require a prescription. Though depending on where you are in the world, you might just have to be over 21 and show an ID.
You might think this sounds like a pretty standard story.
You would be wrong.
Because while the US Navy was the one handing the money to the USPHS, the US Navy had come by it via the Central Intelligence Agency.
Yes. The good ol' CIA.
So what stake did the CIA have in a non-addictive codeine replacement? Nothing, it turns out. That's just what they'd told the US Navy. What they really wanted was an incapacitant- a drug that causes incapacitation like unconsciousness or continuous hallucinations- without killing. Incapacitants are also useful for discrediting prominent political figures by making them look like they have severe mental health concerns, which was another reason the CIA wanted them.
This was part of a project called MKPILOT.
And wouldn't you like to know which of the three listed above they liked the most? Dextromethorphan. Because at high doses it causes severe- and incapacitating- hallucinations (this is also why it is banned in Sweden).
The problem with it is that it requires really, really high doses (about 3 grams, which would have to be packaged in some other substrate)- this would make it difficult to slip into a drink or food.
(It should be noted that around the same time, the US Army was doing research into a much more usable incapacitant called 3-Quinuclidinyl Benzilate which required as little as 150mg of the substance to be useful- it was featured in a MacGyver episode and I did a nice little review of it here. While I have no sources that say the CIA was directly involved in funding this, based on their extensive funding of similar DoD projects at the time, they probably did.)
But you wanted to know about how grapefruit interacts with dextromethorphan:
A substance in grapefruit (along with seville oranges, limes, pomelos, and possibly pomegranates) blocks the pathway by which many drugs are metabolized in the liver. This causes the levels of drug in the body to be much higher than expected. In the case of dextromethorphan in particular, it can mean that the drug stays in the body a lot longer- up to 24 hours instead of the usual 3-4 hours. It can also make side effects and toxic effects significantly worse, leading to hallucinations and sedation, even at low doses normally used for coughing.
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purpleandgreen13 · 2 months ago
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Happy Inktober 2024 Stardew Valley peeps!
I'm using the Grapefruit Sky Stardew Valley Inktober List, twinned with the Stardew Valley Fanfiction Writers Discord. Here's my first contribution: New Clothes Full list is here: STARDEW VALLEY INKTOBER 2024 – @purpleandgreen13 on Tumblr I'm beginning the month with some Shane fluff. Don't faint, this is new for me too :D Don't forget if you're tackling any of these prompts as a writer there is a collection on AO3 you can add to if you want. Stardew Valley Inktober Challenge 2024
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necros-writing-stuff · 2 years ago
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Dare’s cock is 9 inches??? ��‍💫😵‍💫😵‍💫 God now I’m just imaging his first time with a really small wife, him having to basically mold her cunt around his cock,,,
Hammer would be a more appropriate verb here, I think.
I debated making him just like average in the schlong department, but then decided no. He shall be slanging because its another way he can hurt his wife and be an inconsiderate bitch for his own pleasure.
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i-think-i-loved-them-all · 7 days ago
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Journal Excerpt, Wednesday, October 23rd
There is still much to learn about myself. Today I tried a peach, whole, raw, for the first time... I liked it, but disliked the texture of the skin in my mouth. Pleasant to hold in my hand, though.
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dee-daa · 5 months ago
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i think we should start using the citrus scale again
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prozac-shaped-urn · 1 year ago
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Aaaaaaaaand the good shit is here!
Happy reading x
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hertwood · 8 months ago
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Very strong and brave (asked the ticket checker which direction the cafe car is)
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etchif · 10 months ago
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I love making polls so much it's so fun
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Clementines, Mandarins, and Other Orange Cravings: The Dictionary - Page 92
(Volume 1 and only, written by Noone You Need to Know)
Note: I wrote the entirety of this piece to nothing but this song on loop and I highly recommend reading it that way too :) Pg. Index and pg. 225, 401, 145, 159, 167, 152, 151, 60, 92, 134, 149, and 203
grapefruit (o •            • th • ang • ks) prep. the interior gut muscles rotting openly in the corner of your fruit bowl, much to the distaste of your houseguests. too clunky and oafish to share in any meaningful way. dirtybadwrong. [somewhere cold and cruel, most likely unnecessary.] Do not see; orange.
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[Image of an artistic rendition of a grapefruit, stylized for safe human consumption]
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animatedcatastrophe-au · 2 years ago
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Hey guys, I was scrolling though my phone and found some old art work. I really like them and decided to post them here
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Does anyone still remember when pear did that one rock song??? No? Just me? Ok
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olddirtybadfic · 1 year ago
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if this ship sinks, i won't blame the mermaids for eating my fingers off
I may have blueshipped too close to the vortex. Now I'm spiraling in a whirlpool of horny Gyarados and the submarine really isn't helping matters.
-O-o-O-o-O-
Meowth was a sucker for round things. In his gravid state, James fit the description to a “T.”
He gazed across the bed. James was laid out on his back, the moonlight from the window falling on the rise of his kitten bump. His hair fanned out over the pillow like so much blue silk. A slender hand nestled against his lower belly. A moon-pale, delicate foot poked out from under the sheets.
He let his eyes rest on that foot, with its finely shaped arch and soft toes. James often complained about the appearance of his swollen feet, but Meowth saw things differently. The few harsh angles were softened, emphasizing the smoothness of James’s skin. But maybe he was just so attracted to James, it didn’t matter what his feet looked like.
Meowth remembered the experiment that started this whole thing. They’d been asked by Team Rocket labs to participate in a special breeding experiment to determine if humans and Pokémon could interbreed. Since their team wasn’t exactly bringing in the powerful Pokémon, the higher-ups figured they could at least be useful as test subjects.
The fact that Meowth and James had already started a Pokébestial relationship was merely a bonus.
He let his mind drift back to their first breeding attempt. His Jimmy had been a virgin before the relationship, but he learned quick (at least when it came to sex). Within a few tries, Meowth had him squealing so loud, they probably woke the whole forest. Jessie invested in a comfortable set of earplugs after the first few times.
Meowth could hear the falsetto moan James had let out when he slid into him. He could almost get drunk on the memory of that potent perfume of roses, Victreebel saliva, and human pheromones that made up James’s signature scent. As James rolled his hips, the sides of his entrance caressed Meowth’s dick in a warm, wet embrace.
He remembered how James had gripped the sheets as he plunged deeper. James was panting like he’d pedaled the Magikarp sub around the entire Orange Archipelago. The pheromones radiated from hair as blue and wet as any ocean while Meowth plumbed James’s depths.
“Blast me off, Meowth,” James was moaning. “Blast me sky high so I can fall pregnant back to earth!”
So Meowth just started blasting.
That seemed to send James into orbit. His eyelashes fluttered and he twitched all over like he was getting shocked by Pikachu. Meowth vaguely remembered James biting the back of his fingers, as if he needed to balance the pleasure with pain. Meowth couldn’t be sure that was what was happening, though. He was wrapped up in his own climax as he planted his seed in James.
In that moment, he understood completely why Victreebel always wanted a taste of James. The smells coming off of James were sweeter than any Sweet Scent he’d faced in battle (not that he’d been in many battles; Meowth considered himself a different kind of Pokémon).
The scent reminded Meowth that it was now his cue to grab James’s dick and roll it between his paws. Gently, of course—his Jimmy was very sensitive. Just a few swivels were enough to push him over the edge.
Cats excelled at pushing things over the edge.
James’s rocket blasted off spectacularly. The ropes shot out like he’d just deployed a Poké-napping net. By the time he was spent, it looked like a Spinarak shot web across his stomach.
Meowth fell into the spot beside James as both of them basked in the afterglow. Meowth was purring. James was purring. Meowth grabbed James’s hand in his paw. James let out a barely audible sigh.
After they’d calmed down a bit, James had looked down at his stomach. “I made such a mess,” he said in mock remorse.
Meowth had rolled over to watch James clenchingly make his way to the bathroom. He didn’t know why, but he fixated on the pearls of jism rolling down James’s thigh. Probably because they, too, were round. Meowth was always a sucker for round things.
Over the next few weeks, it took them a few more tries, but eventually Meowth knocked James up. And here they were now.
Meowth was brought out of his reverie by a soft yawn. James shifted in his sleep, then opened his eyes and gave Meowth a smoldering half-smile. The half-mast eyelids and pheromone cocktail fanned the two green flames.
His Jimmy was rustled.
-O-o-O-
The heat was rising within James. The urge was upon him again.
James knew he wasn’t really in heat, of course. He was still pregnant, and humans didn’t go into heat, anyway. But as of late, he’d been feeling as though he might start caterwauling if Meowth didn’t stick him right then and there.
Ever since James had entered the latter weeks of his pregnancy, his hormones had been driving him mad. He and Meowth hadn’t copulated since it started and James had discovered quickly that certain desires did not wane, even after they’d served their purpose. His libido was somewhat dampened in the early stages, however. It was hard to get in the mood when one was virtually a vomit fountain.
Fortunately for him, his morning sickness subsided as the gestation wore on. Now his only issue was that he was too sleepy to think about sex.
No…. That wasn’t quite right. James had enjoyed a number of erotic dreams over the past few weeks. They ran the gamut from simple but sweet (James, clapping his buttocks on Meowth’s cock in a sort of anal applause) to stimulating and steamy.
One such fantasy transpired thus. James had washed up, sans raiment, on an unknown shore. The population appeared to consist entirely of tiny talking Meowths. Their Lilliputian leader was a hot air balloonist and announced that he wished to welcome the nude giant. He climbed into a hot air balloon with a phallus affixed to the basket. Just as he was about to dock it in the cave on James’s backside, a tidal wave sprang up from the ocean. James had woken up drenched in sweat. He also needed to change the sheets.
Another saw him as a fiery Moltres, soaring high above the earth. Meowth bounded after him in hot pursuit. James swooped down, flames trailing behind, and landed in a circle of flaming stones. There, he waited and watched as Meowth caught up to him. Meowth marched right into the ring of fire, the words “I am the unburnt,” on his lips. He rode James the Moltres, but not through the sky. James woke from that one feeling very flaming indeed.
Yet another flight of fancy put him in a hall of mirrors in front of a Jack-in-the-Box. Though the reflections were distorted, James could make out that he was sporting pigtails and a clown nose. In place of a crank, the Jack-in-the-Box bore a perfect replica of Meowth’s penis. James instinctively knew to massage the penis on the box. Out popped Meowth, dressed in a harlequin print jester costume. 
At that point in the dream, James’s nipples began to throb; he looked down and saw that they had transformed into bright red orbs, a funhouse mirror image of his clown nose. Meowth seemed intrigued by this; he put his paws on James’s nipples and gently squeezed. Each squeeze produced a honking sound and an arc of milk that Meowth caught in his mouth. James’s nethers were a flower squirting a liquid that was decidedly not seltzer. James awakened from that one with a tent in his pajamas and his teats tender and leaking.
He also had a craving for cream pie and Meowth was the only chef with the recipe.
Back in the present, James felt a flush rise on his face. He was hit by a sudden rush of shame at his loss of mental control, their failure to capture Pikachu, even his dreadful lack of sexual knowledge before the experiment. Meowth practically had to explain sex to him, since his parents hadn’t seen fit to. So many shames; it rhymed with James.
Meowth must have read it on his face. “No, Jimmy,” he said, placing a comforting set of paws on James’s shoulders. “It’s okay. You got needs, too.” Meowth’s voice was gentle, but James could hear undertones of reciprocal rut. The timing was perfect.
“I need you, Meowth. Right now.”
James didn’t need to ask twice. Meowth helped him out of his pajamas—no easy feat, considering how swollen James was at the moment, even with the lubricious luster his lust did muster. Verily, the sweat might have hindered Meowth’s removal of James’s clothing. Waiting only made James more randy. In his delirium, he found himself half whispering, half chanting, “Come, kitty. Come, kitty.”
Meowth chuckled. “We’ll get dere, Jimmy. Don’t getcha panties in a knot.”
“Growlithes have knots,” James thought. “But Meowth has a French tickler dick.” He’d learnt that the first time they coupled. He wondered if Meowth could control each individual nodule, like a Tentacruel and its tentacles. He could never quite remember to ask.
He couldn’t very well ask with Meowth’s lips pressing against his. And as soon as Meowth’s musk wafted into his nose, he forgot completely. The human sense of smell was not as strong as a Meowth’s, but the pregnancy hormones had sharpened James’s nose. Notes of catnip stood out in a scent stream sweeter than that tree sap Victreebel and Heracross loved.
“Like da taste?” Meowth asked, lapping at James’s chin.
“Yes,” James breathed. Baked tuna: James had cooked it for their dinner that evening.
Meowth worked his way down, giving ample attention to James’s nipples. No honking resulted; the only sounds were Meowth’s sucking and James’s low moaning as Meowth’s tongue nodules dandled James's dugs.
“Like the taste?” James drawled.
Meowth grinned. “Your milk’s comin’ in early.”
Meowth moved ever southward, brushing over the great dome that housed their five kittens. James giggled as Meowth rubbed himself all over the sensitive swelling.
“Oh, James, you’re so round.” Meowth swirled his tail around James’s sides. He tongued James’s navel, the nodules tracing the feathery white stretch marks.
James barely heard him. “Goodness gracious….”
“You ain’t seen nuttin’ yet.” Meowth slid himself into James’s crotch. He lifted James’s penis and nudged a feline finger into the orifice beneath. Those kitty beans on his pork sword were getting James nice and marinated.
Meowth noticed instantly. “You’re soaked. Lucky for you, I love dis kinda wet.”
Meowth dove in headfirst. James let out a cry of pleasure as he felt the nodules on his inner walls. He rolled his hips as much as his condition would allow. Meowth gyrated his own hips, causing his penis to stir inside of James like a spoon in cake batter. James kegeled on Meowth’s cock. Would that he had grippers in his nethers; he could massage every node on Meowth’s dick.
Meowth threw his head back, his whiskers fanning around his face. “I’m comin’, Jimmy!” he declared to the stars above. “I think it’s time!” His tail whipped around like a helicopter’s blade.
James was too far-gone to stay quiet. “Fill me with your white tomorrow!” he cried.
Meowth filled James like a cream pastry. James nipped at the back of his forefinger joints. It did little to curb his enthusiasm. He hoped Jessie’s earplugs held up.
But, oh. Oh no. His own cannoli was about to go explody. He’d forgotten to put on protection; he’d have such a mess to clean up and, in his state, he didn’t know if he’d have the energy.
Meowth seemed to notice his mild distress. “Don’t worry, Jimmy. I gotcha.” He pulled out of James and disappeared below the bump.
“Bless him,” James thought, tears misting his eyes. “He’s going to save me the cleanup.” 
Meowth closed his mouth around James’s penis and commenced the fellatio. He was always such a sucker for round things.
-O-o-O-o-O-
*puts on clown nose, walks plank, lands in James and Meowth's sex sweat* TONIGHT WE DINE ON DOVE
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necros-writing-stuff · 2 years ago
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Soft timeout from Darius is just him making you wear a shirt of his that’s saturated in his scent and just putting you in the nest, telling you to get your shit together and remember who your alpha is
Exactly that, except maybe with a little bit of spanking. Darius can have a little bit of spanking. As a treat.
And yes, this always leads to him fingering you after the spanking. And then him on his knees as he goes down on you.
AND THEN you get put in the nest. He'll be back in like 30 minutes to knot you anyways.
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skrillien · 2 years ago
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happy easter?
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killemwithkawaii · 2 years ago
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No better way to word this so Imma just say it: as a fellow peets enjoyer, I would enjoy reading your takes on the SFs Gangs feet. So if you ever need a excuse to talk about it… gestures
(Also calling it. Larry is ticklish as fuck down there which makes most of the kinky stuff one may want to do impossible because he already feels phantom tickles when you just wriggle your fingers in that general direction and becomes an absolutely giggly mess instead. Which also has its charm mind you)
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Anon, it is such a pleasure to be reminded that there are persons with impeccable taste, such as yourself, lurking in the fandom and on my blog, and it's even better when said persons encourage me to be as self-indulgent as you have with this ask. Please accept these headcanons that I thought about way more seriously than I probably should have lmao (I did my best to not let my personal preferences influence them, but a few maaay have sipped through the cracks, and so did yours 🙈💓💦)
What are the Gangs Feet like?-
[CW: Grapefruit (though this is 99% sfw), unsanitary, tickling]
Sally:
-Big feet for his height, greek shape, pronounced metacarpal and ankle bones, arches are a little high.
-Wears shitty off-brand high tops with zero arch support and doesn't seem like the type to own a pumice stone, so there's some callusing on his feet where his shoes rub, but the rest of the skin is relatively soft.
-Typically keeps his nails trimmed purely for comforts sake
-Smell varies from very minimal to strong, depending on whether he's been playing video games or hiking around the woods all day, and whether or not hes had the spoons to change and shower recently.
-Wears soft cotton ankle-length socks (sensory friendly and cushions his very exposed achilles tendons), occasionally with novelty prints. He keeps them on most of the time because his feet get cold easily.
-Sometimes paints his toenails (badly)
-Not ticklish unless you really, really try.
-Hesitant to accept a foot rub, but once you've assured him that you actually want to give him one and he gets used to the feeling, he'll slowly melt into his seat... 🥴
-Blushes if you play footsie with him. 😳
Larry:
-Big ol flipper feet, roman shape, a little wide, average arches.
-Wears sturdy, ankle length work boots with good support, so there's minimal callus, though the skin is overall a little tough.
-Might forget to trim his nails sometimes, and the smell can get pretty ripe if hes been working real hard all day... 😬
-Wears moisture-wicking, mid-crew length socks with strong elastic because he can't stand the feeling of his socks slipping down and bunching at the toe. He has a bad habit of stripping off his socks when he's lounging and leaving them on the floor.
-Has some moles on his feet (just like he has on the rest of him).
-He's ticklish as hell, so touches have to be predictable, deliberate and firm (unless you want to see him reduced to a giggling, thrashing wreck, in which case, do so at your own risk ⚠)
-Would lean back and 'feel like a king' getting his feet rubbed (once it's clear you're for sure not going to tickle him). 👑
-Taps and shakes his feet if he's sitting still for too long.
Ash:
-Larger than average, narrow, greek shape, low arches.
-Used to be that kid that always walked around outside barefoot, but her current use of cosmetics and shaved legs suggests a beauty regimen that would keep her feet looking presentable. She periodically uses a pumice stone, regularly moisturizes, keeps her nails trimmed and occasionally uses nail polish (purple, black or clear).
-Wears supportive, cushioned athletic shoes, and thin, no-show socks, generally in solid colors, but may choose to forgo socks altogether.
-Usually smells like her moisturizer or has a pretty mild scent, unless its especially hot out 🌸
-Average ticklishness
-Could be convinced to have her feet rubbed if it was a mutual thing, or she was especially sore and really needed it.
-Will totally do mani-pendis with a friend! 💅✨️
Todd:
-Average size, egyptian shape, average arches.
-Wears white and grey crew socks and sandals with shorts, so he has a noticeable tan line on his calves. He spends most of his time seated, so they're pretty soft, but the skin can be a little dry in patches.
-Generally keeps his nails tidy, though he can neglect them if he's become hyperfocused on a project, in which case Neil has to remind him to trim them after hes had enough of getting scratched while they're lying in bed togther. 🛌
-Not much of a scent, since the sandals let them breathe.
-Basically impervious to tickling thanks to his parents.
-Will accept the occasional foot rub from Neil, but is more likely to give them, and is pretty good at it, since he's learned a few techniques and pressure points over the years.
-Keeps his socks on most of the time (including during sex) unless it's very hot out. He's just more comfortable that way 🧦
Travis:
-Smaller than average, square shape, low arches.
-Wears mid-crew socks in various colors, sneakers, and dress shoes. Average amount of callous.
-Trimmed nails and almost no scent (he has to shower every day), but that likely changed when he became more involved in behind-the-scenes cult work, and he became increasingly disheveled as he began neglecting his personal hygiene.
-Ticklish to the point of kicking (and will not hold back) 🤬
-Does not like having his feet touched at all (hes touch averse in general), and you probably could not convince him to give a foot rub to anyone under any circumstances without blackmailing him into it. ❌
-Always has socks on unless he's changing or bathing, even when he's sleeping.
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hiraeth12 · 2 years ago
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Your Name
Your name is on the tip of my tongue,
With all the sweetness of cherries,
And all the bitterness of a grapefruit.
The perfect balance of flavours,
Like bittersweet chocolate,
I never want the taste to leave my mouth.
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therichremember · 11 months ago
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Friends, I think this might be misinformation. I could not find any studies backing up the fact that vitamin c affects absorption of adhd medication (if anyone has found any please send them my way). Also, I personally question how vitamin c being present in the stomach would interfere with the meds but stomach acid wouldnt. That being said it wont harm you to not eat any of the foods mentioned in the screenshot for a few hours a day but you might just be depriving yourself of delicious lemonade for no good reason.
(some online articles mentioned that vitamin c lowers the pH of your blood or just 'lowers the pH of your body', which prevents absorption. this is not true. your blood contains buffers to keep its pH within a narrow set range)
There are a lot of articles online repeating this information but they either provide no scientific sources or only reference the document linked above (which in itself provides no sources which is frustrating as hell). This becomes obvious because a lot of them mention the 1000 mg vitamin c dose. The daily recommended intake for most adults is <100 mg.
All that is to say, please don't take medical advice from tumblr at face value (including this addition. Im not an expert either). If your medications are having inconcsistent effects your should discuss this with a doctor or pharmacist if at all possible. Vitamin c is an important micronutrient and one of the easiest to obtain please dont stop eating fruit ok <3.
i know vitamin c basically neutralizes adhd meds but lemonade good
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