#Day’s failed surgery

[maybe-boys-do-love]

lowkey obsessed with Aof Noppharnach’s consistent but subtle shade at Christmas. The Grinch of Thai BL.

[jabberwockypie]

I lived, bitches.

[varjopeura]

.

[iliveinprocrasti-nationn]

one thing abt being disabled/chronically ill that some people don’t get is that sometimes body maintenance that ensures you have the absolute minimum amount of function can also be something that takes away a lot of control and autonomy. you can argue till the cows come home that making those decisions to try and help yourself (or realistically to try to make sure things aren’t worse than they already are) is something that exhibits control and autonomy and stuff, but they can be so limiting in practice because they’re things that take up so much time but have to be done to do anything else

[llycaons]

I wrote a long post abt how hysteria over cheating with AI is borderline irrelevant to my field and how that post implying it's a huge epidemic annoys me and then deleted it bc nobody cares. lol

[chaoswillcalmusdown]

operation "how much estrogen leeway do we have" has commenced and it's only been 2 days but i'm so frustrated my muscles are still acting like they've been through a marathon

[no-face-no-shame]

I hate my fucking university so much it's unreal

[ereborne]

Song of the Day: January 18

"Settle Down" by The 1975

[flintstill]

God I loved that in my neighborhood back where my lease is that the grass gets mowed at like 5pm or a bit later

Fuck ye outside my window I’m trying to go back to sleep

[little-mouse-adventures]

Having a fuckin Thursday, my dudes (gender neutral)

[jabberwockypie]

Filled with perpetual despair that - while my mother traumatized me in multiple ways and left me with physical and emotional scars that I'll carry for the rest of my life - as parents go, like, she's not really even in the Top Ten Worst Parents I know of among people in my social circle?

She did at least recognize that children aren't just . . . potted plants you just have and then don't have to do anything with except yell at them if they make a mess. She understood that children have feelings and need to be taught how to deal with them and that you have to actually engage with your child about their interests and play with them and express that you love them in a way where they like, actually believe it.

Pro-tip: If you can't deal with the fact children make messes, are inconvenient, sometimes annoying, are not just an extension of you, and sometimes you have to say things like "Oh no, what are we going to do, Ariel? :-O" because you have been cast as the fish sidekick in an elaborate mermaid drama? Don't fucking have kids.

Because I will fucking find you and I will tell your kids that you were shit and that the things you did were not okay.

[hardtchill]

Did Vlatko not ring Christen up to see how her journey was going before telling everyone she should be ready for selection in April?

Are you surprised?

[reasonsforhope]

"The first modern attempt at transferring a uterus from one human to another occurred at the turn of the millennium. But surgeons had to remove the organ, which had become necrotic, 99 days later. The first successful transplant was performed in 2011 — but even then, the recipient wasn’t immediately able to get pregnant and deliver a baby. It took three more years for the first person in the world with a transplanted uterus to give birth. 

More than 70 such babies have been born globally in the decade since. “It’s a complete new world,” said Giuliano Testa, chief of abdominal transplant at Baylor University Medical Center.

Almost a third of those babies — 22 and counting — have been born in Dallas at Baylor. On Thursday, Testa and his team published a major cohort study in JAMA analyzing the results from the program’s first 20 patients. All women were of reproductive age and had no uterus (most having been born without one), but had at least one functioning ovary. Most of the uteri came from living donors, but two came from deceased donors.

Fourteen women had successful transplants, all of whom were able to have at least one baby.  

“That success rate is extraordinary, and I want that to get out there,” said Liza Johannesson, the medical director of uterus transplants at Baylor, who works with Testa and co-authored the study. “We want this to be an option for all women out there that need it.”

Six patients had transplant failures, all within two weeks of the procedure. Part of the problem may have been a learning curve: The study initially included only 10 patients, and five of the six with failed transplants were in that first group. These were “technical” failures, Testa said, involving aspects of the surgery such as how surgeons connected the organ’s blood vessels, what material was used for sutures, and selecting a uterus that would work well in a transplant. 

The team saw only one transplant fail in the second group of 10 people, the researchers said. All 20 transplants took place between September 2016 and August 2019.

Only one other cohort study has previously been published on uterus transplants, in 2022. A Swedish team, which included Johannesson before she moved to Baylor, performed seven successful transplants out of nine attempts. Six women, including the first transplant recipient to ever deliver a baby back in 2014, gave birth.

“It’s hard to extract data from that, because they were the first ones that did it,” Johannesson said. “This is the first time we can actually see the safety and efficacy of this procedure properly.”

So far, the signs are good: High success rates for transplants and live births, safe and healthy children so far, and early signs that immunosuppressants — typically given to transplant recipients so their bodies don’t reject the new organ — may not cause long-term harm, the researchers said. (The uterine transplants are removed after recipients no longer need them to deliver children.) And the Baylor team has figured out how to identify the right uterus for transfer: It should be from a donor who has had a baby before, is premenopausal, and, of course, who matches the blood type of the recipient, Testa said...

“They’ve really embraced the idea of practicing improvement as you go along, to understand how to make this safer or more effective. And that’s reflected in the results,” said Jessica Walter, an assistant professor of reproductive endocrinology and infertility at Northwestern University Feinberg School of Medicine, who co-authored an editorial on the research in JAMA...

Walter was a skeptic herself when she first learned about uterine transplants. The procedure seemed invasive and complicated. But she did her fellowship training at Penn Medicine, home to one of just four programs in the U.S. doing uterine transplants. 

“The firsts — the first time the patient received a transplant, the first time she got her period after the transplant, the positive pregnancy test,” Walter said. “Immersing myself in the science, the patients, the practitioners, and researchers — it really changed my opinion that this is science, and this is an innovation like anything else.” ...

Many transgender women are hopeful that uterine transplants might someday be available for them, but it’s likely a far-off possibility. Scientists need to rewind and do animal studies on how a uterus might fare in a different “hormonal milieu” before doing any clinical trials of the procedure with trans people, Wagner said.

Among cisgender women, more long-term research is still needed on the donors, recipients, and the children they have, experts said.

“We want other centers to start up,” Johannesson said. “Our main goal is to publish all of our data, as much as we can.”"

-via Stat, August 16, 2024

[ramblingandpie]

I made this a while ago but I feel like I can reuse it for this.

Someone passing out from fever or sickness, but in a fictional way where you can rush to pick them up and wrap them in a blanket on your couch, not where you call EMS and worry that they might have cracked their head on a sidewalk. Their eyes actually close, unlike in real life where people sometimes faint with their eyes partly or entirely open.

Someone being drugged, but in a fictional way where they glaze over and then gracefully faint, but continue breathing, instead of the real world way, where we have to have a respirator during surgery because substances that produce sustained unconsciousness also tend to paralyze breathing. I like sci fi settings where I can make up drugs for this reason, I know too much about anesthesia.

Someone being put to sleep with magic, which requires no qualifier because it never has medical health risks. I like fantasy settings because of this, too.

Someone passing out from being choked with someone's thighs or arm, but in a fictional way where they stay out without the risk of brain damage or death and they don't lose bowel or bladder control.

The comical clonk on the head is just ruined for me entirely unless it's an overt cartoon, because concussions are scary and subdural hematoma is even scarier.

As a writer I want to do research. As a whump fetishist I have learned that once I have done research, sometimes I harm my own suspension of disbelief. Oops.

[akiriith]

1. I want to play 7R so baaaad

2. Now that I finally started there is so much side stuff that it's kinda overwhelming. And I'm still in the Grasslands OTL.

at least the card game was fun

[butterflyeffectiooon]

Good intentions do not absolve abusive (in effect) treatment :)))))