#Bristol food

[scholarastrid]

The sun is shining, it’s finally getting warm again, and I’m spoiling myself with some Ahh Toots. Delicious croissant cake and cherryade. Perfection!

[whitefireprincess]

Christmas Sandwiches are back! | Sandwich Sandwich

[weather-mood]

that podcast episode… need five business days to recover

[lemonadeboyfriend]

[thiswillnotdo]

2023_05_31

[immortalsins]

i'm aware how lucky i am to have never been short of food (in my parent's house) and always been taken relatively good care of so the fact this is a new experience to me means it's one of privilege. but my dad hasn't bought food in days and he just showed up at my door to ask if i had alcohol requests from the shop in the village ?? hello if you're buying alcohol i'd like to request something to eat

[daimonclub]

Christmas Markets in England

London Christmas markets Christmas markets in England, the best wonderful Christmas markets in London, and in Bath, Bristol, Chester, Winchester, York, Leeds, Birmingham and Manchester The festive period is fast approaching and what better way to celebrate than with a trip to a Christmas market in England? Christmas markets in England mean sparkling lights, gorgeous presents, carol-singers, ice rinks, and mugs of mulled wine, making the winter holiday season a delightful time of year. Every big city has a Christmas Market when the time is right. England’s Christmas Markets are fun, they’re festive and the fragrance of mulled wine on the airwaves keeps the punters coming. Best Christmas markets in London The locations below annually host some of the top Christmas markets in London, which usually stay open until the New Year. Christmas by the River at London Bridge City Christmas By The River at London Bridge City is set against stunning views of Tower Bridge and the Tower of London, offering wooden huts packed with original presents, handmade crafts and plenty of delicious snacks. Indulge in mouthwatering food from an array of pop-up stalls and admire one of London's most iconic skyline views with a steaming cup of mulled wine. Selfridges Christmas Market The Selfridges Christmas Market returns to Edwards Mews again this Christmas. Enjoy sizzling street food from vendors curated by the founder of Street Feast, Dominic Cools-Lartigue, including waffles dripping with chocolate, Filipino treats and pie and mash. This outdoor market brings fairground rides for kids and adults, personalised wreaths made in front of you and heaps of stalls selling Christmas goodies. Winter Wonderland Christmas market The annual Hyde Park Winter Wonderland is situated in one of the city’s most spectacular parks. You’ll find over 100 illuminated wooden chalets decorated in Bavarian style selling handicrafts and fantastic gifts from around the world, including handmade crafts and beautiful pieces of jewellery. You can also enjoy traditional German street food and mulled wine. Winter Follow the lights to Hyde Park and immerse yourself in the festive atmosphere of Winter Wonderland, one of the biggest Christmas markets in London. You can also get your skates on at the UK's biggest outdoor ice rink, see London sparkle from the Giant Observation Wheel, or sit back and enjoy one of Winter Wonderland's top Christmas shows.

Winterville Christmas Market Leicester Square Christmas market Experience festive fun with Christmas in Leicester Square, which gives the home of blockbuster film premieres a yuletide makeover. Browse the traditional market filled with a wonderful array of crafts and tempting treats. Afterwards, head to the Belgian spiegeltent to enjoy a brilliant lineup of comedy, cabaret and magic shows. Southbank Centre Winter Market See the South Bank's riverside transformed into a wintry wonderland, where global cuisine and an artisan Christmas market come together in one sparkling location for Southbank Centre's Winter Festival. Amble past the traditional wooden chalets lining the banks of the Thames and pick up gorgeous stocking fillers from the Winter Market. Or, tuck into cheese-based food, cocktails and mulled wine surrounded by the glow of neon artworks, as part of the Winter Lights display. Eccleston Yards Christmas Market Explore the buzzy open-air mall which makes up this stunning courtyard. Browse stalls filled with trinkets and unique gifts at Eccleston Yards Christmas Market, which brings festive cheer, new traders and live music to this open space during the countdown to Christmas. Treat the special people in your life to London vouchers for top spots or browse luxury Christmas gifts and experiences in the city. Borough Market Tour the historical arches of Borough Market, decked out with lights, decorations and twinkling ornaments, as you source the finest seasonal foods while listening to choirs and buskers singing jolly tunes. Indulge in An Evening of Cheese (15 Dec), or pick up foodie tips and tricks during three days of Festive Kitchen demonstrations (7-9 Dec). From 16 Nov Greenwich Christmas market Tick items off your Christmas shopping list while browsing Greenwich Market's 150 stalls and shops, selling a range of stocking fillers, fashion items, crafts and original artworks. Make sure to also wander around the ancient maritime neighbourhood of Greenwich, which is decked out with lights and festive goodies. Plus, watch as brightly coloured lanterns parade through the area during the Christmas lights switch on.

Christmas markets in England Christmas under the Canopy at King's Cross Get hands-on at craft workshops at Christmas under the Canopy, a covered market found in King's Cross. Following your creative work, browse the array of stalls to find live jazz, carol singers, food tastings, mulled wine and masterclasses at Canopy Market, which welcomes a number of independent, ethical and sustainable vendors. Kingston Christmas Market Venture over to picturesque Kingston upon Thames, where you can search the riverside town's Ancient Market Place for unique Christmas gifts at the Kingston Christmas Market. The cosy cabins are packed with a range of handmade arts and crafts, beautiful decorations and stocking fillers. Afterwards, enjoy seasonal entertainment while tucking into some specialist street food. Other Best Christmas Markets in England Manchester Christmas Markets Birmingham Frankfurt Christmas Market Leeds Christkindelmarkt Bath Christmas Market York’s St Nicholas Christmas Fair Bristol Christmas Market Chester Christmas Market Winchester Christmas Market Manchester Christmas Markets Manchester is home to some of the best Christmas markets in the country and is known as one of the best markets in Europe. There are more than nine of them scattered throughout the city centre, which makes it a true paradise for Christmas enthusiasts! You’ll find a diverse range of food and drink stalls at all of them, each offering a unique experience. The largest market is in Albert Square, which features a German village packed with food and drink stalls. If you’re visiting Manchester in December, it’s a must do!

Manchester Christmas market Birmingham Frankfurt Christmas Market In Birmingham, you can find the largest authentic German Christmas Market outside of Germany. Anyone looking for some Christmas gifts will find beautiful decorations and handcrafted items to choose from, but the real reason to go is for the fab food and drink. Victoria Square is filled with the most delicious smell of Christmas as stalls sell traditional German food. You can sample authentic bratwurst, pretzels, schnitzels, and hot chestnuts. You can even get half-metre sausages, if that sounds good to you – and if you’re thirsty there are four pint jugs of beer or sweet little mugs of flavoured gluhwein too. Leeds Christkindelmarkt Leeds Chrsitkindelmarkt is one of the oldest German Christmas markets in England. Throughout the square are wooden stalls selling beautiful toys, jewellery, crafts, decorations, and other items. A jingling carousel ride with lively music and vibrant coloured lights creates a festive mood throughout the entire Christmas village. The fairground style rides for children and its ‘Breakfast with Santa’ experience are among its most popular attractions. This is a ticketed event that happens on Saturday and Sunday. The Bavarian style restaurant Alp Chalet is in the centre of Millennium Square, and during Christmas, families and kids are invited to enjoy a Christmas breakfast with Santa in traditional German style. Bath Christmas Market Bath hosts one of the most beautiful Christmas markets in England every year. During the winter months, Bath isn’t only wonderful due to its gorgeous architecture, but even more beautiful thanks to its festive atmosphere, and the excellent Bath Christmas Market. A day out in Bath is always a good idea, particularly in winter when it’s definitely one of the best festive days out in the Cotswolds. “With over 130 twinkling chalets, soak up the sights and scents of Christmas as you meander through the cobbled streets surrounded by some of the South West’s most talented crafters. Enjoy a festive experience like no other, surrounded by some of Britain’s iconic architecture. Christmas Markets with stalls are spread all over Bath, on its streets and in small squares surrounding Bath Cathedral.

Bath Christmas Market It’s possible to find independent producers selling their products on many stalls. It’s a great place to find all kinds of handcrafted gifts and decorations, as well as some of the best food and mulled wine. Festive streetlights are strung on the town’s most iconic buildings and streets. A major feature of Bath Christmas Market is the Victorian merry-go-round, suitable for children and adults on the horses or in carriages. York’s St Nicholas Christmas Fair York’s Christmas Market is one of the most picturesque Christmas markets in England. Wooden, alpine-style chalets border York’s pedestrianised city streets, selling locally manufactured crafts, art, food, and drink. Shoppers can enjoy a range of tantalising free samples to try as well as one-of-a-kind presents to purchase. A big, decorated Christmas tree, live entertainment, and beautiful night time illuminations help to create a bright festive mood. Thor’s Tipi, a massive canvas tipi specially created for the Christmas season, is the show-stopper at the Christmas market. Foot-sore customers can relax on soft blankets in front of a roaring log fire and sip mulled wine or creamy hot chocolate and soak up the atmosphere. York Christmas Market is one of the best Christmas days out in Yorkshire! Bristol Christmas Market Bristol Christmas Market in England is more about spending time to appreciate the ambiance and allowing yourself the opportunity to relax or see friends. The Bristol Christmas Market takes place in Broadmead, the city’s Shopping Quarter. It’s a compact but well structured market with a well-planned assortment of booths offering something unique, ensuring you’ll discover the ideal one-of-a-kind Christmas gift. The bar at the heart of the market attracts families with a singing reindeer at the entrance, and while they do serve alcoholic drinks, you can also get a reasonably priced hot chocolate to keep you warm while listening to your favourite festive tunes and watching the frantic last-minute shoppers running past. “Located in the very heart of Bristol City Centre, the Christmas market is home to over 50 unique stalls, as well as entertainment from the likes of Santa and reindeer visits in December. Visitors can enjoy heated seating, delicious drinks and live music in our Jäger Barn Bar, and also try their hand at the much-loved sport of curling for some competitive fun.“

Christmas markets in the UK Chester Christmas Market This mediaeval city in northwest England is notable for its Roman fortifications and walls, as well as Tudor-style timber houses. Then there’s the magical Chester Christmas Market. This is one of the greatest English Christmas markets to visit if you’re looking for something a bit more traditional. Over 70 traditional wooden chalets are situated on the city’s Town Hall Square, with the magnificent Chester Cathedral as a backdrop. Visiting makes for a great day out in Cheshire. Pick up some mulled wine or a tasty hog roast bap after browsing the stalls for handmade crafts, clothing, jewellery, and local produce. Stop by the Real Ale Bar for a Christmas drink or a local cask ale and take a photo in front of the spectacular Christmas tree to really make your Chester Christmas Market experience. Winchester Christmas Market What better way to immerse yourself in the Christmas spirit than at Winchester Cathedral? The monumental Gothic cathedral, in the centre of Britain’s former capital city, towers imposingly over the quaint English Christmas Market, which promises tidings of joy. Winchester has one of the best Christmas Markets in Hampshire, if not England. Follow your nose to stalls touting fine food and drink. Mulled wine in hand, then follow your ears to join the gathered crowd singing along with the carolling choir. And, full of golden festive spirit, mooch around the stalls and support local craftspeople and traders whilst you do your Christmas shopping. https://www.youtube.com/watch?v=X4jsR5PXidU https://www.youtube.com/watch?v=aAJYkO3G8VU Read also our other posts on Christmas  ; Christmas markets in America ; Christmas markets in Italy and Germany ; Christmas quotes ; 60 great Christmas quotes ; Christmas tree origin and quotes ;  Christmas short stories ; Ella Gray A Christmas short story ; Traditional Christmas Carols ; Christmas jokes ; Christmas cracker jokes ; Funny Christmas Stories ; Amusing Christmas stories ; Christmas food ; Christmas thoughts ; Christmas story ; Christmas in Italy ; Christmas holidays ; Christmas songs ; Christmas poems ; An Essay on Christmas by Chesterton ; Read the full article

[rifoodwars]

An example of locally produced propaganda. We have plenty of corn in RI so use it and save wheat!

[veganrecipeclub]

Nominate your favourite Bristol eatery into our Vegan Recipe Club Awards 2023 for a chance to win an exclusive Viva! hamper that includes a year’s free Viva! membership, and access to an extensive discount scheme! 💚

[perrieedwards]

i feel like people are skimming over the uk riots in a way that makes me want to tear my hair out. muslims in the uk are in active danger. immigrants in the uk are in active danger. refugees in the uk are in active danger. people of colour in the uk are in active danger. asian communities in the uk are in active danger. black communities in the uk are in active danger.

there are massive far right riots throughout the country right now and people like fucking elon musk and nigel farage are inciting it and still have a platform to speak. people have used three young girls deaths, people's genuine grief in southport, to try and gain traction for their own racist bullshit and it's working.

a lot of refugee charities have been forced to close leaving many people without support, homes, funding, food, etc. if you aren't able to donate please consider sending a message via the conversation over borders campaign! it will send a hopeful, welcoming letter to a refugee in the uk. there is also a guide to staying safe here.

please do your own research and donate to refugee charities, anti-islamophobia charities, mosques who are trying to rebuild after being destroyed, counter protesters, here are some i've heard positive things about but the list is extensive; southport strong together (support for the southport victims and their families), southport mosque rebuilding, riot repair fund, middlesbrough vulnerable residents, nasir mosque rebuilding, hull help for refugees, bristol welcomes migrants,

[scholarastrid]

I prefer doing editing work with pens on printed paper. The kinetic action of physically striking something off a document or writing in something feels more organized in my brain. Decided to do some editing work in Ah Toots, a cakery and cafe that has immaculate dark academia vibes. Had their vegan Victoria sponge topped with fresh fruit and an excellent dirty chai.

[xtruss]

Food and Drug Administration (FDA) Approves the First New Schizophrenia Drug in Decades

— By Alice Park | September 27, 2024

Steve Belkowitz (Bristol Myers Squibb)

No new treatments for schizophrenia have been approved in nearly three decades, but that changed on September 26, when the U.S. Food and Drug Administration (FDA) approved Cobenfy for the psychiatric disorder.

Developed by Karuna Therapeutics, which was subsequently acquired by Bristol Myers Squibb, the drug works in an entirely different way from existing medications for schizophrenia, which is building excitement and enthusiasm among doctors and patients alike.

How Scientists Developed The New Drug

While schizophrenia treatments primarily target the dopamine neurotransmitter system in the brain, Cobenfy goes after a different one, the cholinergic system, through muscarinic receptors. Decades ago, scientists at Eli Lilly had studied the muscarinic system as a possible treatment for Alzheimer’s disease, since manipulating it seemed to reduce some of the symptoms of Alzheimer’s-related psychosis that some patients develop. The company's researchers also serendipitously learned that a compound they developed to activate the system also improved symptoms of schizophrenia. But cells in many parts of the body—the brain, but also the bladder, gut, salivary glands, eyes, and heart—contain receptors for the muscarinic system, which meant it was challenging to selectively target just those in the brain and not elsewhere. Because the compound, called xanomeline, caused wide-ranging side effects, Lilly's researchers shelved further study on it.

Andrew Miller, co-founder of Karuna, became intrigued by this research and tried to figure out how to activate the muscarinic system in the brain while tamping it down elsewhere in the body. He and his team tested 7,000 compounds and eventually combined xanomeline with a drug that had been approved by the FDA in the 1970s for treating overactive bladder, to suppress muscarinic activity elsewhere in the body. "It's a pretty out-of-the-box approach," says Miller. The overactive bladder drug "has nothing to do with psychiatry," he said. Combining it with a serendipitous discovery of xanomeline "didn't fit the traditional model of innovative drug discovery." But it worked.

What Studies Have Found

In a study the company published last December in the journal Lancet, the researchers reported that the combination—now called Cobenfy but then called KarXT—helped to significantly reduce symptoms of schizophrenia such as hallucinations, delusions, paranoia, social withdrawal, and a loss of motivation compared to a placebo. Those data were part of the application that the company submitted to the FDA for approval.

Bristol Myers Squibb acquired Karuna in 2023 largely based on these encouraging results. “When we looked at the available neuroscience and neuropsychiatric assets out there, we didn’t want the next dopamine agonist or antagonist in the marketplace, which all of the physicians have [already] seen,” says Adam Lenkowsky, chief commercialization officer for Bristol Myers Squibb. “We wanted a truly revolutionary asset, one with a different mechanism: a first-in-class, best-in-category asset we think could transform the space.”

Samit Hirawat, chief medical officer at Bristol Myers Squibb, says that not only does Cobenfy address schizophrenia in an entirely new way, but its approach could be used for other neurological conditions as well. "The breadth of applicability of this medicine is what attracted us.”

Dr. Rishi Kakar, chief scientific officer at Segal Trials who led several studies on Cobenfy, says that “the uniqueness of the mechanism of action differentiated this medication from everything else we had so far, and truly caught my eye right off the bat.” Kakar—a psychiatrist who treats patients as well as conducts research—says that historically, only about 40% of people with schizophrenia respond to dopamine-based treatments, and the other 60% who may respond often stop taking their medications because of intolerable side effects, which can include uncontrolled muscle movements, dizziness, fainting, and weight gain.

The trials included patients who were hospitalized for acute schizophrenia and randomly assigned to receive Cobenfy—as a pill taken twice a day—or a placebo for five weeks. In order to reflect the real-world population of patients, some had been taking existing medications but stopped because of the side effects, or weren’t compliant. All patients went through a wash-out period of up to two weeks to ensure any measurements of their outcomes during the study were due solely to Cobenfy or placebo. Patients received escalating doses of the drug, and prescribing doctors were able to adjust dosages for their patients depending on their symptoms.

The studies documented a significant reduction in overall symptoms of schizophrenia in the patients receiving Cobenfy compared to placebo. “My viewpoint is that [this difference] can mean someone can potentially carry on a better life by having symptom control,” says Kakar.

What Else To Know About Cobenfy

The FDA approved Cobenfy as a monotherapy—meaning it is meant to be taken alone, without other medications—but more studies will be needed to see how the medication works in combination with existing treatments, and what the benefits and risks are of combining them. “I think many clinicians are going to try this as a first-time pharmacological option, because they will find that the reduction in symptoms is fairly robust,” says Kakar. “From what I saw, it has true value for the unmet need we have.” Lenkowsky says Bristol Myers Squibb is conducting a trial studying Cobenfy in combination with dopamine-based medications that will yield results in about a year.

In contrast to the existing dopamine-based treatments, the side effects of Cobenfy reported by the volunteers in the studies were mostly mild to moderate, involving nausea and gastrointestinal distress, and tended to lessen with time. The label also alerts patients that the drug is associated with urinary retention, increased heart rate and swelling in the face in rare cases; the medication is not recommended for people with a history of liver or kidney disorders.

Bristol Myers Squibb is continuing to study the drug for its longer term effects, as well as to understand and potentially guide doctors on how to adjust doses for patients as their symptoms change over time. The success in schizophrenia patients may lead to other uses of the drug in other conditions as well. “Neuropsychiatry is at the cusp of bringing an explosion of new medicines, and Cobenfy is the start of a pipeline of potential products,” says Hirawat. The company is currently studying the drug in Alzheimer’s-related psychosis, and next year plans to start late-stage trials investigating whether it can improve bipolar mania, Alzheimer’s-associated agitation, and Alzheimer’s-associated cognitive impairment. In 2027, the company hopes to begin trials in people with autism.

How Much Will Cobenfy Cost?

According to a Bristol Myers Squibb spokesperson, the wholesale cost for a month's supply will be $1,850. Depending on people's insurance coverage, that cost could be lower for individual patients. Bristol Myers Squibb estimates that 80% of people with schizophrenia in the U.S. have insurance coverage either through Medicare or Medicaid.

[rayjuss]

Novafunk Guest Mix Ray Juss

- Track Title - Artist

1 - Channel - Michael Fakesch 2 - ESTA & LAKIM - W Hotel - Soulection 3 - Break My Heart - Jaygee Rmc 4 - I Wish (Jim Sharp 'Spinna' Edit) - Stevie Wonder 5 - Elkie Brooks - The Rising Cost Of Love - Various Artists 6 - Money's Too Tight To Mention - Valentine Brothers 7 - Personal Information - Jimmy Edgar 8 - You Belong - Hercules And Love Affair 9 - Aaliyah - If Your Girl Only Knew (Ysus Dion Remix) - Ysus Dion 10 - In Sunny G - Werkha 11 - Bailar - performed by Aloe Blacc - J. Rawls 12 - BTB - Moses Boyd 13 - Strawberries In Vinegar - Silhouette Brown 14 - Copacabana [The Reflex Revision] - The Reflex 15 - Dionne - Osunlade 16 - Paused - Kiasmos 17 - We Can Get Down (Groove Chronicles Remix) - Myron 18 - Bloscid - Boxcutter

[formeryelpers]

Lazy Acres Natural Market, 1841 N Western Ave, Los Angeles (Los Feliz), CA 90027

Lazy Acres recently opened in Hollywood. It’s a natural foods store that reminds me of Whole Foods and Bristol Farms. It’s clean, bright, and attractive with lots of organic produce and goods, supplements, and prepared foods. As for the prepared foods, you can build your own poke bowl or order fish tacos, BBQ plates, The salad/hot food bar is $11.99/lb and the food looked tasty. They also have prepackaged sushi, sandwiches, salads, sides, juices, hot soup bar, etc. There’s an in-store bakery and coffee/juice bar as well. The coffee bar serves organic coffee beans and organic milk.

The produce selection is impressive. They even had purple asparagus. The health and wellness selection is large and they also have very cute gifts (plush toys, tote bags), greeting cards, and fresh flowers. And there’s a bulk section. A Mary’s rotisserie chicken is $15.99.

My picks:

Gardein classic meatballs ($4.99): these are faux meatballs

Chicken tamale ($5.99): twice as big as your usual tamale, pretty moist, shredded chicken in a spicy red sauce, pretty good, a bit too salty

Lazy Acres has the same owners as Bristol Farms. Self-checkout is available. I noticed the parking lot had wider spaces – a thoughtful touch. If you want to dine there, they have a dining area. If you bring your own bag, you can ask for a token and then decide how that gets donated. They even have cooking classes.

4 out of 5 stars

By Lolia S.

[trevlad-sounds]

Ode to Rain

11.07.2014

Ten years ago today.

Peter Broderick & Machinefabriek-Rain 00:00 Message To Bears-November 04:54 Koen Holtkamp-Excerpt from "Loosely Based on Bees" 07:54 Andy Quark-Cloud 13:19 Brassica-New Jam City 17:02 Cardioze-Like A Rainy Summer 25:11 Bearhead & Tape Sounds-Anthracnose 29:57 Michna-Through The City On The Edge Of Forever 30:48 Padang Food Tigers-In My Heart I'm Already Gone 35:19 daisuke miyatani-wake up with ice cocoa 38:03 Sangam & Cholombian-Shelter Me 38:29 TONTO's Expanding Head Band-Tama 44:23

[iamjosiahmovie]

Film Scouting www.iamJosiahMovie.com