#period pain

[reasonsforhope]

"A medical technology company in Australia is aiming for a world-first: it wants to launch a blood test for endometriosis (sometimes called 'endo' for short) within the first half of this year [2025].

In a recent peer-reviewed trial, its novel test proved 99.7 percent accurate at distinguishing severe cases of endometriosis from patients without the disease but with similar symptoms.

Even in the early stages of the disease, when blood markers may be harder to pick out, the test's accuracy remained over 85 percent.

The company behind the patent, Proteomics International, says it is currently adapting the method "for use in a clinical environment," with a target launch date in Australia for the second quarter of this year [2025].

The test is called PromarkerEndo.

"This advancement marks a significant step toward non-invasive, personalized care for a condition that has long been underserved by current medical approaches," managing director of Proteomics International Richard Lipscombe said in a press release from December 30.

Endometriosis is a common inflammatory disease that occurs when tissue similar to the lining of the uterus grows in other parts of the body, forming lesions. The disease can be very painful, and yet the average patient often suffers debilitating symptoms for up to seven years before they are properly diagnosed.

While there are numerous reasons for such a long delay, symptoms of endometriosis are often highly variable, unpredictable, difficult to measure or describe, and dismissed or overlooked by doctors.

Today, the only definitive way to diagnose endometriosis is via keyhole surgery called a laparoscopy, which is expensive, invasive, and carries risks.

Proteomics International is hoping to change that.

In collaboration with researchers at the University of Melbourne and the Royal Women's Hospital, the company compared the bloodwork data from 749 participants of mostly European descent.

Some had endometriosis and others had symptoms that were similar to endo but without the lesions. All participants had a laparoscopy to confirm the presence or absence of the disease.

Sifting through the bloodwork, researchers ran several different algorithms to figure out which proteins in the blood were best at predicting endometriosis of varying stages.

Building on previous research, a panel of 10 proteins showed a "clear association" with endometriosis.

For years now, scientists have investigated possible blood biomarkers of endometriosis to see if they could differentiate between those who have endo and those who do not. Similar to cancerous tumors, endo lesions can establish their own blood supply, and if cervical cancer can be diagnosed via a blood test, it seemed possible that endometriosis could be, too...

Proteomics International claims patents for PromarkerEndo are "pending in all major jurisdictions," starting first in Australia.

It remains to be seen if the company's blood test lives up to the hype and is approved by the Australian Therapeutic Goods Administration (TGA). But that's not outside the realm of possibility.

In November of 2023, some researchers predicted that a "reliable non-invasive biomarker for endometriosis is highly likely in the coming years."

Perhaps this is the year."

-via ScienceAlert, January 9, 2025

--

Note: As someone with endometriosis, let me say that this is a HUGE deal. The condition is incredibly common, incredibly understudied, and incredibly often dismissed. Massive sexism at work here.

I got very lucky and got diagnosed after about 6 months of chronic pain (and extra extra lucky, because my pain went away with medication). But as the article says, the average time to diagnosis is seven years.

Being able to confirm endometriosis diagnoses/rates without invasive surgery will also lead to huge progress in studying/creating treatments for endo.

And fyi: If you have a period that is so painful that you can't stand up, or have to go home from school/work, or vomit, or anything else debilitating (or if any of those things apply if you forget to take pain meds), that is NOT NORMAL, and you should talk to a competent gynecologist asap.

[magentasnail]

as part of trying to have a better relationship with my body I'm trying to not think of the uterus as evil like this:

but rather as trying it's best while being a bit useless, like this:

[deesi-academia]

I think it's high time we invent a way for a person to transfer their period pains and symptoms to their current most hated misogynistic "alpha" male

[wisherbysharlight]

It took me nearly 15 years to get my endometriosis diagnosis and comprehensive treatment, but I recognize I’m super privileged in being able to access care where I live from one of the top doctors in endometriosis research(specifically endometriosis in adolescents, but his research spans all age groups). I want to share some of the things I learned, along with study sources he linked me to, so others can advocate to their providers for the care they need. So without further ado:

✨ What I Wish I Knew About Endometriosis 15 Years Ago ✨

No amount of pain is “normal”

Don’t get gaslit into thinking “everyone” who has periods goes through pain. Seek treatment - you deserve better.

Diagnosis/treatment is kinda a pain, even with a doc who takes you seriously

The general course of action for diagnosis/treatment will be attempt treatment through OTC painkillers (Tylenol, Midol, etc), attempt at least 1-2 forms of hormonal birth control(typically oral contraceptive/birth control pill or the ring/patch/shot), then decide with your doctor whether to pursue either further hormone treatments, such as GnRH(which suppress estrogen/can help stop progression of endo) or an IUD, and/or surgical intervention where they go in and find/remove the existing lesions.

Surgery for me took a couple hours, and I had an IUD placed during the operation(at recommendation of my doc). Full recovery was around 2 weeks. Its worth noting right now you can technically only be diagnosed through surgery.

You may have to mix-and-match to find the right solution.

Only 33% of people with endometriosis in a recent controlled study saw significant improvement by IUD alone, as compared to IUD with supplementary hormonal treatment(like oral birth control or hormone inhibitors). Source: https://www.sciencedirect.com/science/article/abs/pii/S1083318812002379

Some options may actually make it worse. Keep an eye on your symptoms.

Studies show that estrogen based treatments can potentially exacerbate endometriosis and promote endometrial growth, so treatments without estrogen or with specific types of estrogen are more recommended. Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC5683134/

Its Got Hella Comorbidities

Fibromyalgia, scoliosis, arthritis, thyroid disease, migraines, chronic fatigue, and bowel disease(IBS, crohn’s, celiac, etc), and more are all potential associations/comorbitities. It’s also worth noting that having any of these in your family history may also put you at higher risk for endo. As my doc said - you’re not guaranteed to get all, or even any, of these, but they’re things to keep an eye out for. Sources:

IBS: https://pmc.ncbi.nlm.nih.gov/articles/PMC9357916/

IBD/Crohns: https://pubmed.ncbi.nlm.nih.gov/32629225/

Celiac: https://pubmed.ncbi.nlm.nih.gov/24992792/

Thyroid: https://pmc.ncbi.nlm.nih.gov/articles/PMC10234359/

Migraine: https://pubmed.ncbi.nlm.nih.gov/38436302/

Painful Bladder Syndrome: https://pmc.ncbi.nlm.nih.gov/articles/PMC3015716/

EDS: https://www.sciencedirect.com/science/article/abs/pii/S0002937824001637

Arthritis: https://pubmed.ncbi.nlm.nih.gov/35258592/

Scoliosis: https://pubmed.ncbi.nlm.nih.gov/9238674/

TMJ: https://pmc.ncbi.nlm.nih.gov/articles/PMC10144081/

Kidney Stones: https://pmc.ncbi.nlm.nih.gov/articles/PMC9108729/

POTS: https://pmc.ncbi.nlm.nih.gov/articles/PMC3413773/

Fibromyalgia: https://pubmed.ncbi.nlm.nih.gov/30682223/

Chronic Fatigue: https://pmc.ncbi.nlm.nih.gov/articles/PMC6537603/

Sjogren’s Syndrome: https://pubmed.ncbi.nlm.nih.gov/39083399/

Bonus Advice

No published studies exist showing any increase/decrease of symptoms between usage of different menstrual products. Do whatever makes you most comfortable!

For OTC pain management, Tylenol or Aleve may be your best bets over Advil, based on their anti-inflammatory nature.

He also recommended probiotics pretty heavily, since digestive issues(ie bad period poops) are super common. Any with >10Bn active cultures are good!

(Disclaimer: I am not a doctor, just someone that learned a lot and wants to share)

[scary-friend]

✨I’m not doing well✨

[cottoncandycasketspray]

[immadatdisney2]

What are some of your favorite VAT7K headcanons (personal or popular within the fandom)??

My first question!

Okay, so I'll list my favorites because I have WAY too many

Nurus dress has pockets (as all dresses should)

Hugo hates having his hair down because he doesn't like how it feels when it brushes against his neck

Olivia can play music through her little speakers

Hugo's is basically a polyglot and his main languages are English, French and Igvarian

When they aren't fighting, Hugo and Nuru love to braid each other's hair

When Varian finds out Yong loves baking, he always sets some time aside to awake with him after each trial

Hugo has a bad habit of picking his nails till they bleed when he's stressed or anxious, so to help Varian starting painting his nails just like he would with Rapunzel back in Corona

One time for his birthday, Donella got Hugo a pair of Goggles with his same glasses prescription so he could actually use them functionally

Hugo will eat anything but he's not a big fan of meat, avoids it when he can and seafood makes him sick to his stomach

Hugo steals and wears Nurus earrings just to piss her off

Hugo never bully's Nuru when she's on her period, always makes sure she has some kind of tea or hot towel and makes sure the others don't bother her if she's uncomfortable (especially Varian who will most likely pass our just knowing she's bleeding)

Yong got really good at playing pranks thanks to Hugo

thease are just a couple of my favorites (sorry for so many Hugo he's, he's kinda my favorite) and let me know if you'd like to hear anymore!!! <3<3<3

[donutenthusiast]

My period cramps are hurting like a motherfucker and let me tell you, nothing sounds better than cuddling the flaming donut himself, using his body heat as a way to soothe the cramps, snuggling closer into his chest and inhaling his comforting scent as we fall asleep...

I'm craving some genuine domestic affection rn and this man is emitting some crazy husband vibes

[slickver-draws]

ITS THAT TIME OF THE MONTH!!!! AAAAAHHHH

[getinthecar-elizabeth]

Title: Period Pain Sneak Attack

Summary: Kylian rescuing you from your surprise period.

Pairing: Kylian Mbappé x Wife!reader

♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡

You've always had painful periods, but you had found a way to manage them. You made sure to track your period and had a stash of painkillers with you when you knew it was coming.

But this time you didn't see it coming. Mainly because it came early. You realized that eating too much beetroot was not such a good idea. You were at your mother-in-law's house for dinner over a week ago and Fayza had made the best beetroot you'd ever tasted. When you left you asked for some and she packaged it for you in a container. You ate the beetroot day and night for an entire week and now you were suffering the consequences.

Worst of all you were not home. You were at a restaurant celebrating your husband's younger brother, Ethan's birthday.

You felt that familiar wetness between your legs and thought it was just your ovulation. But after a couple of hours, a certain discomfort in your lower abdomen sent you to the bathroom. To your surprise, you were met with blood.

You didn't want to leave early and seem rude so you didn't say anything. Luckily, you had a pad in your purse and you managed to get a painkiller from someone at the party, but unfortunately, you were too far gone.

You patiently waited for the medicine to take effect but the pain only got worse. The next time you went to the bathroom the nausea had taken over and you threw up. The pain had gotten to the point where you could feel it in your knees, making your legs weak.

Your husband noticed that you were gone for too long so he went to look for you. He found you outside the lady's bathroom. You were leaning against the wall and bent over with your hand on your stomach.

"Mon amour (my love), what's wrong?" He rushed to your side and put his hand on your back.

"Period pain," you muttered in pain.

"Oh no, you don't have your painkillers?" He asked.

You answered him by shaking your head.

"Okay, let's get you home," he helped you stand up straight.

Kylian knew it was bad. You could barely walk and you couldn't stand up straight on your own. You leaned your body against him as he helped you walk.

"Attends ici (wait here)," he left you by an empty table and hurried to get your things. He whispered something in his mother's ear who turned to look at you and nodded while giving you a sad look. She knew how much your period bothered you.

Kylian returned to your side and helped you to the car. He opened the passenger door for you and helped you settle in before clipping your seat belt in place. He got into the driver's seat and started the car (let's assume he can drive in this one). He drove you home as fast as he could without committing any traffic violations. He kept on looking over at you. The pain was written all over your face. You were breathing heavily and shaking.

When you got home, he parked the car in the garage and carried you into the house. He carried you to your bedroom and gently placed you on the bed. You lay on your side in a fetal position, your arms wrapped around your belly.

He ran downstairs to the kitchen and put the kettle on. He grabbed a bottle of water from the water cabinet and brought it to the bedroom. You were already stripping out of your dress when he got back. He got your painkillers from the side drawer and gave you two and the water to drink. He took the bottle from you when you were done and placed it on the bedside table.

He went to the closet and got you a comfy set of pyjamas to wear. He helped you put them on and tucked you in. He got your hot water bottle from the bathroom and went back to the kitchen. The kettle was done boiling when he arrived. He poured the hot water into the bottle, closed it tight and made sure it wouldn't spill. He brought the bottle back into the bedroom and covered it with a towel so it wouldn't burn you. He placed the water bottle under the covers near your stomach.

You hugged the bottle close to you and thanked him.

Kylian stripped out of his clothes and put on a pair of sweatpants. He got under the covers behind you and pulled you close to him. He rubbed your back as he listened to your moans of pain. It was all he could do at this moment.

After a while, he noticed that you had gone still and quiet. He looked over you and saw that you were asleep. The pain on your face was replaced with a calm expression and your painful moans with gentle breaths. He was glad that you were not in pain anymore.

♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡♡

[smolomega-9]

Headache pains has me like

[ghxstyfae]

Cramping ♡ R.Cameron

Synopsis: Headcanons of Rafe × reader on her period with bad cramps (/endo/pcos/etc.)

Warnings: mentions of heavy bleeding, bad cramps, medications, possibilities of drug use, labelled nsfw section

(Sfw)

Look, Rafe is an actual asshole and hes never really had to worry about any of his exes on their periods. He didnr care enough

But he legitimately loves you, and seeing you in pain breaks his heart.

At first it took some learning... "Kid, im sure its not that bad. Dont you all get this every month?"

But after seeing balled up in a *very* unusual positon, tears flowing freely, he starts doing anything in his power to help alleviate your pain.

He has a little container he puts out on his bathroom counter when you're on your period for pads/tampons/whatever u use

And another basket in his closet that has heating pads, midol (and other pain medications), chocolate and other snacks, and obviously extra boxes of any products you use.

If you are someone who has an extreamly heavy flow and bleed through things alot you dont need to be embarrassed w him.

He'll keep darker sheets for when your on your period and has no problem washing them and anything you need. "No worries Doll, i got a bubble bath in there, just go relax baby." 🫶🏻

If you find it helps with the pain, he'll offer weed. He loves getting you all high and brainless, especially when youre so anxious and emotional on your period, its easier to just let him think for you

Cuddles cuddles cuddles

"Let me rub the pain away baby"

Keeps the lights off and makes sure youre all snuggled up with some blankets, heating pads, an emotional support water bottle, and snacks if he needs to leave you alone

Which he probably wont too much throughout the cycle. I mean, if you want space he can leave the room?

Whenever someone else comments on how "overdramatic" hes being he gets so pissed.

Eventually this teaches him abt periods in general and hes able to help Wheezie out if need be

(Nsfw)

Would never be opposed to period sex. Hes a grown man (in his head smh) and doesnt mind getting messy, plus if you cumming will help with the pain, whos he to say no?

Speaking of cumming, you on your period and being in so much pain activates his breeding kink sfm...

"Come on Sweetheart, lemme fill you up. Gonna put my baby in your tummy, yeah? If i keep you full youll never have to deal with this again hm?"

[lucifer-is-a-bag-of-dicks]

hey if your period literally fucking cripples you every month but everyone keeps telling you that's normal and you're just overreacting

consider that it might not be normal

I've been on the depo shot contraceptive for several years longer than you're supposed to because it manages these symptoms, I had to go off it for a while by doctor suggestion to reassess if I still need it, my period has been back for three days and I'm seeing my doctor TODAY to get back on depo because I just can't handle the physical and emotional toll it takes on me

this shit is genuinely crippling, I cannot function, don't let people convince you that this is normal, listen to your body and get help

[nicxxx5]

y'all why did evolution decide bleeding for a week straight was favorable for survival?

why have periods not been lost been lost to evolution???

why were periods introduced by evolution?!?!?!

natural selection what the fuck

[manisimp]

You need a Cup of Tea?

Hello.Im on my Period right now and did a Drabble.Have fun.

WC: ~1,230.

Pairing: Tsukishima Kei x Fem! Reader

CW: Period Pain,Insecure Reader.Fluff.Really fluffy.

(Whish i Had someone to Take Care of me Like that)

You we're writhing on your bed, attempting to find a compfortable Position to Rest in despite the cramps in your lower abdomen,but it seems Impossible.You already took pain meds AND cramp-loosening Meds,But to No avail.The endless cramps that dig into your flesh Like hot Cuts seem to only  worsen.You groan in dissatisacftion.Why does Life have to be Like this?

Knock-Knock.

Someones at your door.You frown.Anything but company right now.You Hope they go away when you ignore it,But then you hear him.His voice.

"Y/N,i know youre in there.Let me in."

That voice alone,even with the slight harshness to it,makes you feel a bit better.But only a bit.

You groan as you sit up,crawling over your bed to Stretch to your doorhandle and Open it.You have No strength to sit up.

What you See when the door Swings open is excatly what you expected.Tsukishima Kei,your Boyfriend.He Looks Like always.Beige sweater,Headphones around His neck,And the Sports bag thrown over the shoulder.He probably came Here straight from practice.

But his face is focused,zeroed in on you.You can See the slight furrow of his brow,His hard,almost Distant eyes skimming over your slightly trembling Form,with your own arm over your Belly.And then his eyes find yours,grow less Distant,but still questioning.

"I missed you today.You werent waiting for me after practice."

You feel a pang of guilt.Its Tuesday,and normally,you Pick him Up after Practice on Tuesday.You rarely miss it.And you even forgot to Text him.

You Dip your head in shame.

"im sorry,Tsukki,i forgot-"

You Stop when He tilts your face up with one Finger.

"Tell me whats wrong,Y/N."

His words are Level,flat.Almost.Anyone who didnt know Tsukki would think He was concealing Anger,with how his eyes narrow and and He now Cups your entire Jaw.

You know better.You know thats him careing.Hes trying to figure it out before you tell him.

"M' on my Period.I forgot to Tell you,Kei.Im sorry."

"You NEVER forget."

That hits.Because yeah,you never forget him.Never,Ever.You Always let him know if Something Happens,if you cant come.Always, unless...

"Its bad,isnt it?"

His voice now carries a softer undertone,His understanding of you getting that at that when you even forget to Text him,it must be Bad.

Which it is.

And the sudden Hit of a cramp that makes you fold Forward and let Out a silent groan dosent Help.

You cant do anything but nod.

"Tsukki,I-"

You were intending to say youre fine,that you can handle yourself,but IT falls on dead ears.Your Boyfriend already has taken Control,carefully but firmly pushing you down on the mattress again.

And only a few Minutes later,youre curled around him,His finger drawing Lazy circles in your side as you feel the warmth of the bed bottle seep into your abdomen and a nice bottle of Woman's-Coat Tea in your Hand,both courtesy of him.

"you didnt have to do that all, Tsukki" you say,but Silently very grateful that He did do that all.The warmth of the bed bottle and the Tea actually spread throughout you,making you feel warm and lengths better than what you did Just Minutes ago.

But First and foremost,what helps is him,His Love,His Care.Even if Hes Just sitting There,caressing your Side like Second Nature while Reading His Book -something about Dinosaurs,If you can guess from the cover- even if Hes not cocooning you in Care and touches,you feel cared for.

Because His eyes Dart to yours every so often,checking silently if youre still okey.

Because His Hand Just cant keep Off of you,Sometimes inching to your Abdomen to Check how tense it is,massaging IT gently with one Hand Till he thinks its good.

Because you know,with one ear,He listens to your rambles about anything and everything,even If Hes reading.

Because He dosent leave your Side.

"you seem to really Like that i did that though, judging by how much youre cradling that bed bottle."

He responds,finally, looking at you over the rim of His glasses.

"also,your cheeks have much more colour now.Im doing Something right."

"i mean,yeah,im Not complaining -"

"You are."

"i mean,im not Mad that you did it!Im Just,yk,i wouldve Survived without you doing-that."

He Rolls His eyes and groans silently at that.

He hates that.When you think you arent worthy of His affection or whatever.

He Puts His Book aside,Completly focused on you now.He Turns to face you fully,His now free Hand cupping your cheek,Feeling how warm and flush it is.He let His thumb caress the smooth skin.

"you gotta Stop doing that,Y/N.Its Not attractive"

"Uhm, Tsukki,what?" You furrow your brow.You've Always been reluctant to admit that you are worthy of His Attention and care,and today is No diffrent.If anything,the cramps make IT worse.

"You need to Stop thinking youre not deserving or whatever.Can you do that,Y/N?Just let me Care for you because i want to."

He cocks His head,and smirks.And you already know whats coming next from that smug Expression.

"at least thats what you Always say to me,Sweetheart.'

Tóuche.You do.

Whenever you Care for Kei,and He pushes you away for whatever reason,you insist that he 'let you Love him because you want to.'

Too Bad your weapon now got used against you.You Hiss weakly, suddenly Feeling Exposed.But not in a Bad way.

You desperately Scramble at words,trying to find a retort,but the pain,the painful twist and tug in your abdomen,the suddeness of his words and His cocky grin dont make IT easy.

Before you can even think of a retort,He Laughs.He Laughs,cocky yet sweet,so full of Care,yet absolutely teasing you.

He Looks Back at you,the corners of His eyes crinkled when he Brings his Other Hand to your cheek to,cupping your face.Hus golden eyes sparkle with barely veiled affection.

He lightly squeezes your cheeks in a teasing manner,before he gives your lips a quick peck.

"a realtionship IS a two way road,you know ,Princess?"

He says,His words nothing but true affection that hit you right in the Heart and make you feel all fuzzy inside.You know him,and Moments Like These are to be cherished.They arent often.

"Despite,you Look awful when you're in pain.Much cuter when youre curled around me and ramble Like the usual annoying nerd you are."

And Hes Back to His teasing.You Fake a frown , playfully Hurt by His words.You pout.

"Tsukki,that wasnt nice."

"Well,you arent Dating me because im nice."

You attempt to Roll your eyes,but before you can complete the Roll, your eyes are forced shut by another felt kiss to your lips,Slow and affectionate this time.One Hand of his moves to the Back of your head,tilting it a bit,and your hands let go of the bed bottle to instead cradle him,falling around His neck.

When you let go,you cant Help but Smile happily.

Tsukishima Kei might be teasing,sarcastic and to some, emotionless,but to you,Hes everything you ever needed and wanted.

Youd wouldnt give him Up for the world.

"You need another Cup of tea?"

Note: In Case anyone wondering,Womans Coat is a herbal Tea that helps with Period cramps and various other Things.I Always take it and OT helps a Lot.