#molecular structure
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science-lover33 · 2 years ago
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Exploring the Marvels of Biological Macromolecules: The Molecular Machinery of Life (Part 3)
Proteins and Enzymes: Catalysts of Molecular Reactions
Proteins are the central players in macromolecular interactions. Enzymes, a specialized class of proteins, catalyze biochemical reactions with remarkable specificity. They bind to substrates, facilitate reactions, and release products, ensuring that cellular processes occur with precision.
Protein-Protein Interactions: Orchestrating Cellular Functions
Proteins often interact with other proteins to form dynamic complexes. These interactions are pivotal in processes such as signal transduction, where cascades of protein-protein interactions transmit signals within cells, regulating diverse functions such as growth, metabolism, and immune responses.
Protein-Ligand Interactions: Molecular Recognition
Proteins can also interact with small molecules called ligands. Receptor proteins, for instance, bind to ligands such as hormones, neurotransmitters, or drugs, initiating cellular responses. These interactions rely on specific binding sites and molecular recognition.
Protein-DNA Interactions: Controlling Genetic Information
Transcription factors, a class of proteins, interact with DNA to regulate gene expression. They bind to specific DNA sequences, promoting or inhibiting transcription, thereby controlling RNA and protein synthesis.
Membrane Proteins: Regulating Cellular Transport
Integral membrane proteins participate in macromolecular interactions by regulating the transport of ions and molecules across cell membranes. Transport proteins, ion channels, and pumps interact precisely to maintain cellular homeostasis.
Cooperativity and Allosteric Regulation: Fine-Tuning Cellular Processes
Cooperativity and allosteric regulation are mechanisms that modulate protein function. In cooperativity, binding one ligand to a protein influences the binding of subsequent ligands, often amplifying the response. Allosteric regulation occurs when a molecule binds to a site other than the active site, altering the protein's conformation and activity.
Interactions in Signaling Pathways: Cellular Communication
Signal transduction pathways rely on cascades of macromolecular interactions to transmit extracellular signals into cellular responses. Kinases and phosphatases, enzymes that add or remove phosphate groups, play pivotal roles in these pathways.
Protein Folding and Misfolding: Disease Implications
Proteins must fold into specific three-dimensional shapes to function correctly. Misfolded proteins can lead to Alzheimer's, Parkinson's, and prion diseases. Chaperone proteins assist in proper protein folding and prevent aggregation.
References
Voet, D., Voet, J. G., & Pratt, C. W. (2016). Fundamentals of Biochemistry: Life at the Molecular Level. Wiley.
Lehninger, A. L., Nelson, D. L., & Cox, M. M. (2017). Lehninger Principles of Biochemistry. W. H. Freeman.
Berg, J. M., Tymoczko, J. L., & Stryer, L. (2002). Biochemistry. W. H. Freeman
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polarmolecule · 2 years ago
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molecular geometry my sweetheart my baby. electron orbitals kill yourself.
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animegirlsayingwow · 1 year ago
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I’m dumb but convinced this says something, does anyone know how to read molecular structures?? Got this at the thrift shop yesterday.
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moaan · 9 months ago
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Hey! by Katsuaki Shoda Via Flickr: Canon EOS R6m2 + RF24-105mm F4L IS USM
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cylexplastics · 4 months ago
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Weather resistance and corrosion resistance of PVDF
In the vast starry sky of material science, polyvinylidene fluoride (PVDF) is like a shining star, illuminating the way for many industrial applications with its excellent weather resistance and corrosion resistance. As a high-performance fluoropolymer, PVDF stands out among many materials with its unique molecular structure and chemical properties, and has become an indispensable key material in…
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aanews69 · 10 months ago
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All our links in one place:https://sleekbio.com/aanews69Visit our Patreonhttps://www.patreon.com/DNPLServicesWe deliver stories. We also give you guides, tip...
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tenth-sentence · 1 year ago
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In the next several sections, we describe how these measurements are made for nuclear spin states of these two isotopes and then how this information can be correlated with molecular structure.
"Chemistry" 2e - Blackman, A., Bottle, S., Schmid, S., Mocerino, M., Wille, U.
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zorangezest · 25 days ago
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(part 4) fun for the whole family continues!!
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did you spot rumble? :)
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just-null · 2 months ago
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(LATE) MAID DAY!!!!!!!!!
extra:
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kyannnite · 1 year ago
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murderous tendencies be damned my boy can work a violin
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tsuchinokoroyale · 2 years ago
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You are what you eat and baby I’m always making that jello jigglers resippy 😏
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garaks-padded-bra · 4 months ago
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You ever have arguably too much Nutella and it like fucks you up a little
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alliebirb · 4 months ago
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Atom Eve next season needs less time as Mark’s therapist and more time going balls to wall w/ her OP powers!!!! I’m tired of this green lantern object generation, have her turn the air in a viltrumite’s lungs into mayonnaise!!!!!!!
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myheartisbro-ken · 8 months ago
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My brain, every other second for the past 6 weeks straight gay: what if we rewatched Agatha All Along?
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enderwoah · 2 years ago
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what's stronger than a diamond?
take this antarctic empire inspired fusion design of phil and techno! he was real fun to design (my favourite bit is his cape, it turns into mist at the very bottom like a waterfall (or into snow, your choice)) :D
also fun fact, this was lined with a feather pen that i had to dip into an inkwell :D my lining pen was broken by my siblings but this had the perfect nib !
red king design by @cherrifire + the gemcyt au by @chrisrin!
stupid doodle under the cut:
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fuckytrollbabies · 6 months ago
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First little group of intros, more coming soon. :)
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