#cell expansion

[botanyone]

Are Giant Tomatoes the Future of Climate-Resilient Crops?

Gigantism, a common domestication trait in many crops, triggers a disproportionate growth in edible parts like stems, leaves or fruits. In a recent study by Mateus Vicente and colleagues, published in Annals of Botany, the researchers at the University of São Paulo in Brazil identified the locus that controls vegetative and reproductive organ size in tomato.  Tomato, scientifically known as…

[whats-in-a-sentence]

Upon binding to IDA, the HAE/HSL2 receptor complex is thought to trigger the MAPK cascade, which leads to the transcriptional activation of genes encoding cell wall loosening enzymes, cell expansion, and cell separation (Figure 22.25).

"Plant Physiology and Development" int'l 6e - Taiz, L., Zeiger, E., Møller, I.M., Murphy, A.

[tenth-sentence]

These lateral root primordia cells continue cell division and cell expansion until the new lateral root emerges through the cortical and epidermal cell layers (Figure 18.37).

"Plant Physiology and Development" int'l 6e - Taiz, L., Zeiger, E., Møller, I.M., Murphy, A.

[technolgy0411]

Global Cell expansion Market Insights and It’s Growth Outlook By 2027

An exhaustive evaluation of restrains included in Cell expansion Market report portrays dissimilarity to drivers and hence, gives room for tactical planning. Characteristics that overshadow market progress are as essential as they can be understood to advance different bends for getting hold of lucrative scenarios that are existing in this ever-growing market. Furthermore, insights into the key specialist’s opinions have been well-thought-out to understand this market better.

The study elaborates growth rate of the Cell expansion Market supported and analysed after exhaustive and reliable company profile analysis. The study offers an in-depth investigation, market size, share, insights, evaluation for developing segment and numerous other important market characteristic in the Cell expansion Market industry.

The Prominent/Emerging Players in the Cell expansion Market includes:

BD (US) Merck KGaA (Germany) Thermo Fisher Scientific, Inc (US) Terumo Corporation (Japan) General Electric Company (US) Corning Incorporated (US) Miltenyi Biotec (US) Danaher (US) Lonza (Switzerland) Stemcell Technologies, Inc (Canada)

The global Cell expansion Market segmented by company, region (country), by Type, and by Application. Players, stakeholders, and other participants in the global Cell expansion Market will be able to gain the upper hand as they use the report as a powerful resource. The segmental analysis focuses on revenue and forecast by region (country), by Type, and by Application for the period 2019­­­­­­–2027.

Cell expansion Market Segment by Regions, regional analysis covers

North America (United States, Canada and Mexico) Europe (Germany, France, UK, Russia and Italy) Asia-Pacific (China, Japan, Korea, India and Southeast Asia) South America (Brazil, Argentina, Colombia etc.) Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)

The report currently provides detailed insights on trends, market share, market size, market value, and trading volume. The global Cell expansion Market report provides a comprehensive analysis of COVID-19 infections and how it has impacted market growth. This study explains the future opportunities for market participants. In addition, the market includes recent collaborations, mergers, acquisitions, and partnerships along with regulatory frameworks across different regions impacting the market trajectory.

Research objectives:

To study and analyze the global Cell expansion Market size by key regions/countries, product type and application, history data from 2018 to 2020, and forecast to 2028. To understand the structure of Cell expansion Market by identifying its various sub segments. Focuses on the key global Cell expansion Market players, to define, describe and analyze the value, market share, market competition landscape, SWOT analysis and development plans in next few years. To analyze the Cell expansion Market with respect to individual growth trends, future prospects, and their contribution to the total market. To share detailed information about the key factors influencing the growth of the market (growth potential, opportunities, drivers, industry-specific challenges and risks). To project the size of Cell expansion Market submarkets, with respect to key regions (along with their respective key countries). To analyze competitive developments such as expansions, agreements, new product launches and acquisitions in the market. To strategically profile the key players and comprehensively analyze their growth strategies.

Table of Contents: Cell expansion Market

Part 1: Overview of Cell expansion Market Part 2: Cell expansion Market Carts: Global Market Status and Forecast by Regions Part 3: Global Market Status and Forecast by Types Part 4: Global Market Status and Forecast by Downstream Industry Part 5: Market Driving Factor Analysis Part 6: Market Competition Status by Major Manufacturers Part 7: Major Manufacturers Introduction and Market Data Part 8: Upstream and Downstream Market Analysis Part 9: Cost and Gross Margin Analysis Part 10: Marketing Status Analysis Part 11: Market Report Conclusion Part 12: Cell expansion Market: Research Methodology and Reference

About Us:

The Insight Partners is a one stop industry research provider of actionable intelligence. We help our clients in getting solutions to their research requirements through our syndicated and consulting research services. We specialize in industries such as Semiconductor and Electronics, Aerospace and Defense, Automotive and Transportation, Biotechnology, Healthcare IT, Manufacturing and Construction, Medical Device, Technology, Media and Telecommunications, Chemicals and Materials.

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If you have any queries about this report or if you would like further information, please

Contact Person: Sameer Joshi

E-mail: sales@theinsightpartners.com

Phone: +1-646-491-9876

[enkimesh-truther]

Whats the story behind ur url??

no but like literally

[bpod-bpod]

Centriole Building

The centriole – an organelle vital for the faithful separation into each daughter cell when a cell divides – is composed of an assembly of proteins. Using expansion microscopy, this study correlates the spatial location of 24 of those proteins with structural features of the human centriole, and then models the molecular architecture of the centriole as it assembles (shown here)

Read the published research article here

Video from work by Marine H. Laporte and colleagues

University of Geneva, Department of Molecular and Cellular Biology, Faculty of Sciences, Geneva, Switzerland

Video originally published with a Creative Commons Attribution 4.0 International (CC BY-NC 4.0)

Published in Cell, April 2024

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[hewkii]

if sanitized octarians don't have vitals are they able to heal from injury? bc healing requires cell division, which requires oxygen, which requires a blood flow, which requires at least one beating heart

although since sanitized ink is made of other organisms maybe they're able to absorb cells out of it rather than creating their own. that would mean they'd need new sanitized ink every time they get hurt. that could become a problem now that there's (presumably) no more being produced 🤔

[wersa]

wait i just realized we finally get valeera and liadrin in the same place this xpac please please please i am on my knees-

[notoriousthicc]

Don't open until christmas! <3

[quietwingsinthesky]

even has killed people—though perhaps that depends on your definition of people—and it’s not. how do i put it. it’s never cool, you know? it’s never a moment where this puts them in control of a situation, where they can show off some skill in putting someone down. because even is not, generally, very powerful, and they do not know how to do this.

it just gets messy.

which is one of those terrible reasons why they… well, they don’t like the master, but they have to like that she can do it easy, quick, clean. she can give even the ability to, as well, when she wants. if for no other reason than it means that they won’t have to scrub it raw off their skin later, they appreciate that.

[sidewalkchemistry]

Maintaining a great level of metabolic activity is important because it helps your temperature regulation. So, if you get very easily cold or hot, or if you find it hard to tolerate the cold or heat of your climate, your metabolism is a key part of the equation!!

[whats-in-a-sentence]

Ethylene regulates a wide range of responses in plants, including seed germination and seedling growth, cell expansion and differentiation, leaf and flower senescence and abscission, and responses to biotic and abiotic stresses, including epinasty (Figure 15.12B).

"Plant Physiology and Development" int'l 6e - Taiz, L., Zeiger, E., Møller, I.M., Murphy, A.

[industrynewsupdates]

Cell Expansion Market Insights: A Look at Regional Growth and Opportunities

The global cell expansion market was valued at USD 17.75 billion in 2022 and is expected to grow at a compound annual growth rate (CAGR) of 12.85% from 2023 to 2030. This growth is primarily driven by advancements in automated solutions for cell expansion, the increasing demand for cell therapy products (CTPs), and the development of gene therapies and other biologics. Automation in the cell expansion process plays a crucial role in minimizing manpower and costs, while simultaneously enhancing the reliability and efficiency of production systems, leading to more robust and consistent processes.

As the cell expansion market evolves, technological advancements are not only improving the scalability and cost-effectiveness of production but also helping ensure higher product quality and efficiency. The demand for gene therapies and biologics is growing, especially in the treatment of complex diseases, and this is driving the need for more effective and optimized cell expansion solutions.

For example, in January 2021, Thermo Fisher Scientific introduced the Gibco CTS OpTmizer Pro Serum-Free Media platform, a specialized solution aimed at improving the development and expansion of human T lymphocytes for cell therapy developers working with allogeneic workflows. This platform is specifically designed to target donor cell metabolism, making it ideal for developing off-the-shelf, allogeneic cell therapies. By eliminating the need for serum and providing a more controlled environment for cell growth, this serum-free media platform offers a more cost-effective, scalable, and reliable solution for cell therapy manufacturing.

This product is a significant advancement in addressing the manufacturing challenges faced by developers of allogeneic therapies, where donor variability and the need for scalable production are key concerns. The introduction of such innovations by industry leaders helps to ensure that companies are better equipped to meet the increasing demand for cell-based therapies and biologics globally.

Gather more insights about the market drivers, restrains and growth of the Cell Expansion Market

Regional Insights

North America

In 2022, North America accounted for the largest revenue share of 39.0% in the global cell expansion market. The region is expected to maintain its leading position over the forecast period due to a combination of factors, including increased funding from both government agencies and private organizations. These funding initiatives are critical in accelerating the manufacturing of stem cells and the development of regenerative medicines and cellular therapy products, which are driving the demand for cell expansion platforms in North America.

The investment in regenerative medicine and cell therapies in the region is expected to continue to grow, as the need for more effective treatments for conditions such as cancer, neurological disorders, and cardiovascular diseases increases. In addition, the presence of key players in the biotechnology and pharmaceutical industries, along with a well-established healthcare infrastructure, further bolsters North America's dominance in the market. The ongoing focus on stem cell research and biologics development will continue to fuel the demand for advanced cell expansion technologies in the coming years.

Asia Pacific

The Asia Pacific region is projected to experience the fastest compound annual growth rate (CAGR) of over 15.0% during the forecast period. This rapid growth can be attributed to the increasing efforts of local pharmaceutical and biotechnology companies in the region to develop and commercialize their cellular therapies. As the biopharmaceutical sector in countries like India, China, and Japan expands, the need for advanced cell expansion technologies to support the production of cell therapies is becoming more pronounced.

A key example of the region’s growing focus on cellular therapies is the collaboration between Alkem Laboratories and Stempeutics in September 2022, which led to the launch of “StemOne”, the first off-the-shelf cell therapy product for treating knee osteoarthritis in India. The product received regulatory approval from the Drugs Controller General of India (DCGI), marking the first approval of an allogeneic cell therapy product for commercial use in the country. This significant development reflects the growing investment in regenerative medicine and cell therapy in India and is expected to further drive the demand for cell expansion platforms in the region.

The Asia Pacific market is also supported by factors such as increasing healthcare spending, advances in biotechnology, and the growing prevalence of chronic diseases. As companies in this region continue to make strides in developing new cell therapies and biologics, the need for advanced cell expansion solutions will continue to grow.

Browse through Grand View Research's Medical Devices Industry Research Reports.

• The global biologics market size was valued at USD 461.74 billion in 2022 and is expected to grow at a compound annual growth rate (CAGR) of 10.3% from 2023 to 2030. 

• The global cell therapy market size was estimated at USD 4.74 billion in 2023 and is expected to grow at a compound annual growth rate (CAGR) of 22.66% from 2024 to 2030.

Key Companies & Market Share Insights

The cell expansion market is highly competitive, with several key players focusing on expanding their market presence through a variety of strategies, including collaborations, partnerships, product development, and expansion into untapped regions. To maintain a competitive edge, these companies are increasingly leveraging cutting-edge technologies and innovative solutions to meet the growing demand for cell-based therapies.

Strategic Collaborations and Developments

1. STEMCELL Technologies and Applied Cells Inc. entered into a partnership in April 2022 to create an innovative solution for cell separation. The collaboration combined STEMCELL’s EasySep kits with Applied Cells’ MARS platform to enhance the ease and automation of isolating cells from different biological samples, such as whole blood, bone marrow, apheresis products, and tissues. This advancement will improve the efficiency and effectiveness of cell isolation for both research and medical purposes, significantly enhancing the overall cell expansion process.

2. In May 2023, panCELLa and BioCentriq signed a research agreement to explore stem cell-derived Natural Killer (NK) cell expansion technology. The collaboration aims to evaluate panCELLa’s genetically engineered feeder cells, which are designed to enhance the expansion rate, total yield, and potency of NK cells. NK cells have gained attention for their role in immunotherapy, particularly in treating cancers, and the collaboration is expected to improve the efficiency of NK cell production, facilitating the development of new therapies.

Key Companies in the Cell Expansion Market

The global cell expansion market is driven by a number of leading companies that specialize in providing innovative products and solutions to support the production of cell therapy products. Some of the prominent players in the market include:

• Thermo Fisher Scientific, Inc.

• Corning Incorporated

• Merck KGaA

• Miltenyi Biotec

• BD (Becton, Dickinson and Company)

• Terumo BCT, Inc.

• Sartorius AG

• Takara Bio Inc.

• TRINOVA BIOCHEM GmbH

• upcyte technologies GmbH

Order a free sample PDF of the Cell Expansion Market Intelligence Study, published by Grand View Research.

[luckydige45]

The global cell expansion market is valued at USD 18.75 Billion in 2023 and is projected to reach a value of USD 60.08 Billion by 2033 at a CAGR (Compound Annual Growth Rate) of 12.35% between 2024 and 2033.

[enkimesh-truther]

Thank you, everyone! Happy Halloween!

[bpod-bpod]

Blown-up in Blood

An atlas of development of the malaria parasite as it proliferates in its blood cell stage generated using expansion microscopy – a means of physically inflating tissue to enhance the microscopic view

Read the published research article here

Image from work by Benjamin Liffner and Ana Karla Cepeda Diaz, and colleagues

Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, IN, USA

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in eLife, December 2023

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