#antibiotic medicines

[monopharmacare]

Quality Healthcare Access: Mono Pharmacare Ltd, Fulfilling Antibiotics Needs in India...

Specializing in antibiotics, Mono Pharmacare Ltd operates as a prominent supplier within India's pharmaceutical market. With a focus on quality and reliability, the company contributes significantly to meeting the country's healthcare demands.

[foxett]

The 5 rw group making flower crowns post game ? :3

Hey guys i bring the

[reasonsforhope]

"An international research team has found almost a million potential sources of antibiotics in the natural world.

Research published in the journal Cell by a team including Queensland University of Technology (QUT) computational biologist Associate Professor Luis Pedro Coelho has used machine learning to identify 863,498 promising antimicrobial peptides -- small molecules that can kill or inhibit the growth of infectious microbes.

The findings of the study come with a renewed global focus on combatting antimicrobial resistance (AMR) as humanity contends with the growing number of superbugs resistant to current drugs.

"There is an urgent need for new methods for antibiotic discovery," Professor Coelho, a researcher at the QUT Centre for Microbiome Research, said. The centre studies the structure and function of microbial communities from around the globe.

"It is one of the top public health threats, killing 1.27 million people each year." ...

"Using artificial intelligence to understand and harness the power of the global microbiome will hopefully drive innovative research for better public health outcomes," he said.

The team verified the machine predictions by testing 100 laboratory-made peptides against clinically significant pathogens. They found 79 disrupted bacterial membranes and 63 specifically targeted antibiotic-resistant bacteria such as Staphylococcus aureus and Escherichia coli.

"Moreover, some peptides helped to eliminate infections in mice; two in particular reduced bacteria by up to four orders of magnitude," Professor Coelho said.

In a preclinical model, tested on infected mice, treatment with these peptides produced results similar to the effects of polymyxin B -- a commercially available antibiotic which is used to treat meningitis, pneumonia, sepsis and urinary tract infections.

More than 60,000 metagenomes (a collection of genomes within a specific environment), which together contained the genetic makeup of over one million organisms, were analysed to get these results. They came from sources across the globe including marine and soil environments, and human and animal guts.

The resulting AMPSphere -- a comprehensive database comprising these novel peptides -- has been published as a publicly available, open-access resource for new antibiotic discovery.

[Note: !!! Love it. Open access research databases my beloved.]"

-via Science Daily, June 5, 2024

[mindblowingscience]

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut. The drug, called lolamicin, also warded off secondary infections with Clostridioides difficile, a common and dangerous hospital-associated bacterial infection, and was effective against more than 130 multidrug-resistant bacterial strains in cell culture. The findings are detailed in the journal Nature. "People are starting to realize that the antibiotics we've all been taking—that are fighting infection and, in some instances, saving our lives—also are having these deleterious effects on us," said University of Illinois Urbana-Champaign chemistry professor Paul Hergenrother, who led the study with former doctoral student Kristen Muñoz.

Continue Reading.

[cookiewishesyou]

On this September 28, 2024, Cookie wishes you a clinical 95th anniversary to the bacteria-killing mold being noticed by Alexander Fleming while growing in his laboratory - later known to be penicillin (1928)!

[featheryalarmclock]

taste of his own medicine

Headcanon that I will stand by: Harvey LOVES to be taken care of whenever he's sick cuz he's a certified dork Also having an ex-doctor wife must be a real pain in the butt during flu season 🙄

[nerdgirlnarrates]

On the Value of Source Control:

ID Doc: what’s the best antibiotic?

Intern:……Meropenem?

ID Doc: wrong, it’s a good surgeon

[heardatmedschool]

“If you ever prescribe an aminoglycoside, and the patient doesn’t come back complaining because it fucked up their digestion, it’s because they didn’t take it.”

[wikipediapictures]

Etest

“Etest being used to determine the susceptibility of Neisseria gonorrhoeae to benzylpenicillin.” - via Wikipedia

[wronghands1]

[courtingwonder]

How To Make Penicillin --- From "The Book", pg. 34-35

[haveyouever-polls]

Have you ever stopped taking an antibiotic treatment before the end of the prescription (and without the stopping being caused by undesirable effects/lack of pills)?

(you can be honest, these polls are anonymous)

[resonanteye]

you can have hope.

photos from my partner's treatment for leukemia (B-ALL ph+) and bone marrow transplant, 2018-19.

(suggested that I tag in @hopepunk-humanity so I will)

[buscemifan]

please … no more utis for me ever … PLEASE

[mindblowingscience]

Antibiotics are the linchpin of modern medicine: without them, anyone with open wounds or needing to undergo surgery would be at constant risk of dangerous infections. Yet we continue to face a global antibiotics crisis, as more and more resistant strains of bacteria are evolving, while the rate of discovery of fundamentally new antibiotics has been much slower. But there is reason for hope: 70% of all currently licensed antibiotics have been derived from actinobacteria in the soil, and most environments on Earth have not yet been prospected for them.

Continue Reading.

[atomicstarburstlabware]

medicinal chemistry ☕🖤