#and not about... the healthcare

[colorisbyshe]

I do think it's interesting (yet extremely predictable) that the meme-ification of and conspiratorial thinking around Luigi has 100% smothered the embers of intentional movement. If you spend all of your time talking about how he didn't do it, someone else did, he's totally been framed you end up spending no time on actually talking about... what to do next?

A movement where no one actually did anything and nothing actually happens will always be a movement where no one does anything and nothing actually happens.

But it was always obvious it was going to go this way and it's gonna keep going this way because people are more interested in seeming smart and seeing the truth and jokes where no one else sees them than they are in like... figuring out what to do next

And I'm not above that, I don't know what to do next besides things so abstract they're meaningless but like... if there was a communal interest in doing this, it'd be much easier to figure this shit out together instead of just all of us, separately, spewing things so abstract they're meaningless

But tbh this post is a week late, everyone has moved on because no one has the attention span for a movement anyways

[bluesky-out-of-context]

[reasonsforhope]

A new treatment combining ReCET and semaglutide could eliminate the need for insulin in type 2 diabetes, with 86% of participants in a study no longer requiring insulin therapy. The treatment was safe and well-tolerated, and further trials are planned to confirm these results.

Groundbreaking research presented at UEG Week 2024 introduces a promising new treatment approach for type 2 diabetes (T2D) that has the potential to greatly reduce or even eliminate the need for insulin therapy.

This innovative approach, which combines a novel procedure known as ReCET (Re-Cellularization via Electroporation Therapy) with semaglutide, resulted in the elimination of insulin therapy for 86% of patients.

Globally, T2D affects 422 million people... While insulin therapy is commonly used to manage blood sugar levels in T2D patients, it can result in side effects... and further complicate diabetes management. [Note: Also very importantly it's fucking bankrupting people who need it!!] A need therefore exists for alternative treatment strategies.

Study Design and Outcomes

The first-in-human study included 14 participants aged 28 to 75 years, with body mass indices ranging from 24 to 40 kg/m². Each participant underwent the ReCET procedure under deep sedation, a treatment intended to improve the body’s sensitivity to its own insulin. Following the procedure, participants adhered to a two-week isocaloric liquid diet, after which semaglutide was gradually titrated up to 1mg/week.

Remarkably, at the 6- and 12-month follow-up, 86% of participants (12 out of 14) no longer required insulin therapy, and this success continued through the 24-month follow-up. In these cases, all patients maintained glycaemic control, with HbA1c levels remaining below 7.5%.

Tolerability and Safety

The maximum dose of semaglutide was well-tolerated by 93% of participants, one individual could not increase to the maximum dose due to nausea. All patients successfully completed the ReCET procedure, and no serious adverse effects were reported.

Dr Celine Busch, lead author of the study, commented, “These findings are very encouraging, suggesting that ReCET is a safe and feasible procedure that, when combined with semaglutide, can effectively eliminate the need for insulin therapy.”

“Unlike drug therapy, which requires daily medication adherence, ReCET is compliance-free [meaning: you don't have to take it every day], addressing the critical issue of ongoing patient adherence in the management of T2D. In addition, the treatment is disease-modifying: it improves the patient’s sensitivity to their own (endogenous) insulin, tackling the root cause of the disease, as opposed to currently available drug therapies, that are at best disease-controlling.”

Looking ahead, the researchers plan to conduct larger randomized controlled trials to further validate these findings. Dr. Busch added, “We are currently conducting the EMINENT-2 trial with the same inclusion and exclusion criteria and administration of semaglutide, but with either a sham procedure or ReCET. This study will also include mechanistic assessments to evaluate the underlying mechanism of ReCET.”

-via SciTechDaily, October 17, 2024

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Note: If it works even half as well as suggested, this could free so many people from the burden of the ongoing ridiculous cost of insulin. Pharma companies that make insulin can go choke (hopefully).

[incognitopolls]

This is asking about any significantly life altering or life threatening physical disease, infection, or accident that a medical specialist would have needed to test/treat you for.

Anon had a cancer scare that thankfully turned out to be benign, but some bad info and a long waitlist made for a very stressful time. They're wondering how many others have been there!

–

We ask your questions so you don’t have to! Submit your questions to have them posted anonymously as polls.

[wilwheaton]

[irlcupcake]

10 of my favorite easy glow up tips! 𐙚 ‧₊˚ ⋅

get a gua sha!! not expensive at all and made such a difference in my face shape and carving out my cheek bones and jawline. there’s lots of good tutorials on tiktok or youtube!

tea in the morning/night! there’s so many teas to help with different things but my favorite’s are spearmint tea for clearing skin and green tea for reducing bloating.

ice your face! helps SO much with de-puffing and closing up your pores! dipping your face in a bowl with ice water can reduce inflammation, help with acne and reduce oily skin!

make sure to get enough sleep! It’s so easy to stay up scrolling on tumblr until the sun comes up but getting enough sleep is so important mentally and physically!

find a skincare routine that works for you and remember too much skincare can be bad for your skin! my skin was breaking out the worst when i was using a bunch of skincare and It’s cleared so much since i simplified my routine.

use a lash/brow serum! my favorite brand is grande lash and it’s a little pricey but using castor oil works as well and it’s super affordable.

going on walks! I’ve never been a fan of intense exercises and I’m a chronic bed rotter but putting on my favorite hot girl playlist and strutting on the treadmill/sidewalk is genuinely so fun!

rosemary oil for hair growth! my holy grail of hair growth products along with a scalp massager. my whole life my hair grew so slow and since using rosemary oil i have to trim my bangs twice a month sometimes!

i cannot stress this one enough..wear what YOU want! don’t let new trends or judgment from others stop you from embracing your true style. we look our best when we feel most confident!

most importantly ~ take care of yourself! make sure you’re eating enough, drinking water, listening to your body and being gentle with yourself always. improving ourselves can be so fun but make sure it’s not at the expense of your mental health <3

[gmaybe666]

free luigi the new italian american folk hero

[faerygardenparty]

Idk it just annoys me as someone who was heavily affected by a mass shooting and had to suffer through a media parade of “he was just a poor bullied mentally ill kid who sat alone at lunch 😢” nonstop right after not knowing if I’ll ever see my friends again, only for THIS to be the fucking case where all of a sudden everyone grows a conscious and decides we’re not allowed to sympathize with the killer, like fuck right off, I spent the latter half of high school wondering if I was going to be next, there are still days where I can barely stand to be out in public places, I don’t actually give a shit that billionaire CEOs with their private security teams are crying about how scary it is and they don’t know if they’re going to be next and how we should all feel so so bad for them, that same sympathy was never extended to me or my loved ones so why should I give it to them?

[can-we-be-kind]

I genuinely wonder if this is going to start something

Will more people start killing CEOs?

Are there more people willing to potentially give up their freedom for the ‘greater good’?

How many people are in the position to actually access a weapon and be within proximity to a billionaire?

Will there actually be a revolution?

Are people too scared to actually start something?

Are the people who want to, too young, too weak, too ill, ect. to actually be able to do something?

Are you able to actively do something?

Are you able to go outside right now and kill a CEO?

Are the charities working? Are the protests working? Are the movements working?

Is it really getting better?

Maybe if you don’t like something, you should do something.

I dunno man, maybe 1700s France was onto something

[haberdashing]

Musings on the "depose" part of "deny, defend, depose":

When I first read those words, my mind, like most people's I think, read "depose" in the sense of "overthrow". Like how you'd depose a king, kicking him out of his position of authority, in a way that may or may not involve him losing his life as well as his power over others.

But when I mentioned it to a friend, that friend brought up that the word has a second meaning that might be relevant here as well.

In the legal field, "depose" is the verb form of "deposition". Deposition itself is one of the ways you can go about getting evidence from somebody. A deposition is when you get someone to swear that they're telling the truth, and you ask them questions, or ask them for explanations, and they have to answer truthfully. Documents might be part of a deposition, but it's not about the documents themselves, exactly; it's about what they mean, the essential truth behind what the documents describe.

(In my line of work, this might be something like, "Does that income amount listed on your court filing include this bonus listed in your bank statements?" but with a lot of questions leading up to that one to establish things like the bonus being from their employer and deposited into their bank account.)

In a way, it's like the cross-examination part of a trial isolated. (Assuming that it's the other side being deposed; it could also be a witness or third party, but almost by definition you only do depositions on a party that isn't your own client in the case.) One side asks the hard questions, and unless those questions break rules, the other side has to answer them. And like cross-examination, if someone's not truthful in a deposition, that can cause them to face all sorts of sanctions for perjury.

Now, it's very probable that the assassin in this case meant the word only in the more commonplace sense of the word, comparing the CEO to a ruler that needs to be removed from power. But when you consider the legal definition of the word, it seems almost like an ultimatum:

Tell the truth about your unjust business practices, or else lose your power to enact them.

Be deposed, or else be deposed.

[erinwantstowrite]

i am absolutely baffled by the amount of people who keep calling the CEO killer "just like Batman" because I thought it was common fucking knowledge that that man does not use guns??? and does not kill???? before I even got into Batman that was very much something that I knew. just because he is a vigilante does not mean that he's like Batman. I've even seen people call him the Joker???? what planet are you fucking living on??? if you want to compare him to a Batman character look at literally half of his kids when they're having a bad day. I'm more inclined to believe that this is something Jason Todd would do, if he somehow was like "I need to be discreet about it" for the first time in his life. honestly I can see Tim doing it. I know they keep saying that Tim did not kill anybody when he blew up all of the League bases... but let's be real for two seconds. Tim Drake has an alternate future where he becomes Gun Batman. he knows how to create multiple fake identities for himself and rarely gets caught. in a timeline where he wasn't losing his shit and was planning out a murder meticulously for a reason and a message it'd be like this. Jason and Tim both have the dramatics to put the Monopoly money in a backpack. Actually they'd consider this a bonding exercise and do it together

[hollow-keys]

THEE funniest thing about the Luigi Mangione case is establishment pundits trying to misapply class rhetoric to defend the healthcare executive like "Luigi Mangione came from a rich family, Brian Thompson worked his way up from middle class America" like broooo no way are you trying to weaponise misapplied idpol to gloss over real proletarian and bourgeoise dynamics and frame a fucking healthcare executive as more disadvantaged brooo you're only proving how out of touch you are with the material realities of class if you think any of this changes the material power Brian Thompson had and wielded over millions of people for a profit brooo you're trying to bring Clintonian idpol to a class warfare fight and you are going to lose SKSKEKAJDJ

[incognitopolls]

*Not counting routine checkups or normal doctor's visits– this is asking about serious illness, injury, etc where you were in a bed.

–

We ask your questions so you don’t have to! Submit your questions to have them posted anonymously as polls.

[doomdoomofdoom]

you know what, maybe living through historical events isnt so bad if they're fun ones

[closingremarks]

[inkskinned]

you have to go to work so you can pay for your doctor, who is not taking your insurance right now, and if you say i can't afford the doctor's you are told - get a better job. it is very sad that you are unwell, yes, but maybe you should have thought about that before not having a better job.

(where is the better job? who is giving out these better jobs? you are sick, you are hurting - how the hell are you supposed to be well enough for this better job?)

but you go to the doctor because you had the nerve to be hurt or sick or whatever else. and they tell you that it is because you have anxiety. you try your best. you are a self-advocate. you've done the reading (which sometimes pisses them off worse, honestly). you say it is actually adding to my anxiety, it is effecting my quality of life. so they say that you are fat. they say that all young people have this happen to them, isn't it a medical marvel! they say that you should eat more vegetables. they say that you probably just need to lose a little more weight, and that you are faking it for attention.

(what attention could this doctor possibly give? what validation? that's their fucking job, isn't it?)

there is always a hypochondriac, right. someone always tells you about a hypochondriac. or someone who is unnecessarily aggressive during the worst days of their life. or someone looking "for a quick fix". or some idiot who wasn't educated about how to properly care for themselves who just abandons their treatment. and again, the hypochondriac, the overly-cautious hysteric. these people don't deserve to be treated like humans (right), and since you might be one of these people, you also don't get treated like a human. because those people can really fuck with the system, you now have to pay for it. and besides. you're actually probably faking it.

(more often than not, you find a 2:1 ratio of these stories. for every "hypochondriac", there are 2 people who knew something was wrong, and yet nobody could fucking find it. the story often ends with pointless suffering. the story often ends with and now it's too late, and it's going to kill me.)

you are actually just making excuses. someone else got that procedure or that diagnosis and he's fine, you should be fine too. someone else said they watched a documentary about other inspirational people with your exact same condition, maybe you should be inspirational, too. you're just too morbid. your pain and your experience is probably just not statistically concerning. it is all self-reported anyway, and you're just being a baby.

(once, while sitting down in the middle of making coffee, you had the sudden, horrible thought - i could kill myself to make the pain stop. you had to call your best friend after that. had to pet your dog. had to cry about it in the shower. you won't, but that moment - god, fuck. the pain just goes on and on.)

you know someone who went in for routine surgery and said i still feel everything. they told her to just relax. it took her kicking and screaming before they figured out she wasn't lying - the anesthetic drip hadn't been working. you know someone who went in for severe migraines who was told drink water and lose weight. you know someone who was actively bleeding out and throwing up in the ER and was told you're just having a bad period.

in the ER there are always these little posters saying things like "don't wait! get checked today!" and you think about how often you do wait. how often the days spool out. you once waited a full week before seeing the doctor for what you thought was a sprained wrist. it had actually been broken - they had to rebreak it to set it.

but you go into the doctor. the problem you're having is immediate. the person behind the counter frowns and says we're not taking your insurance. you will be paying for this out-of-pocket.

they send you home with tylenol and a little health packet about weight loss or anxiety or attention deficit. on the front it has your birthday and diagnosis. you think about crying, and the words swim. it might as well say go fuck yourself. it might as well say you're a fucking idiot. it might as well say light your money on fire and lie down in it. and the entire fucking time - the problem persists.

it's okay. it's okay, it's just another thing, you think. it's just another thing i have to learn to live with.