#Not Medical

[stoicmike]

If you sleep with people who have troubles, you will certainly catch them. -- Michael Lipsey.

Inspired by Nelson Algren's, "Never play cards with a man called Doc, and never sleep with a woman whose troubles are worse than your own." But I never gambled, at least with cards...

[rivetgoth]

It's honestly crazy that discussion around testosterone HRT skews so much towards the beginning stages of it (to the point that you have dozens of guys thinking their transition is "failed" if they don't pass by like a year in lol) and what the initial changes of the first couple of months to years look like, like the classic laundry list of those early basic changes like bottom growth, voice drop, etc, when IMO literally none of that compares remotely to the depth and intensity of the long term total masculinization you start to experience like 3-5+ years in.

[neurotypicalabusesurvivor]

This is a friendly reminder that none disabled people often do benefit from the same accommodations disabled people benefit from.

[powpowhammer]

faded blue house portrait hanging on the wall at the local urgentcare

[icarusinfreefall]

reminder that adhd medication isn't a luxury or preference, but a lifesaving medication. a 10 year long study in the usa showed that, when properly medicated, the rate of car crashes people with adhd get into goes down significantly--men's rate drops by 38%, and women's by 42%. the med shortage, denial of meds by doctors, rising prices, and the "war on drugs" has killed--with such a car dependent society, not driving frequently isn't an option, which means we need better healthcare and need it now.

https://shorturl.at/8VD8B

edit because i forgot to explain: short link is to an article by the washington post, it should be free to read

[beaft]

i went to get my t-shot yesterday and it took me an hour and a half to get to the clinic and as soon as i got on the bed the nurse dropped my t-shot and it broke and now they're trying to make me pay for the replacement. i think the fuck not lmao

[mostly-funnytwittertweets]

[system-of-an-up]

"Life is too short, ask your crush out"

Bro, I'm dead inside, not even crying because I'm at my lowest, rejected and my life is still short in addition to making me want to shorten my life

I won't kms though I don't want him to think he's the cause of all that especially when I asked him if we could meet up as friends to our usual weekly activities (archery 🏹)

I was lucky the rejection was sweet though but wtf you mean "I've known you for way too long to go out together sorry but you're a very good bro to me"

What is too long tho

I kinda wanna know

[wanologic]

sorry danny, sam will never think you’re cool

[accidentalkilljoys]

What order do you take pills in?

A followup post, because this has been fascinating!

[daisywords]

One of my biggest nitpicks in fiction concerns the feeding of babies. Mothers dying during/shortly after childbirth or the baby being separated form the mother shortly after birth is pretty common in fiction. It is/was also common enough in real life, which is why I think a lot of writers/readers don't think too hard about this. however. Historically, the only reason the vast majority of babies survived being separated from their mother was because there was at least one other woman around to breastfeed them. Before modern formula, yes, people did use other substitutes, but they were rarely, if ever, nutritionally sufficient.

Newborns can't eat adult food. They can't really survive on animal milk. If your story takes place in a world before/without formula, a baby separated from its mother is going to either be nursed by someone else, or starve.

It doesn't have to be a huge plot point, but idk at least don't explicitly describe the situation as excluding the possibility of a wetnurse. "The father or the great grandmother or the neighbor man or the older sibling took and raised the baby completely alone in a cave for a year." Nope. That baby is dead I'm sorry. "The baby was kidnapped shortly after birth by a wizard and hidden away in a secret tower" um quick question was the wizard lactating? "The mother refused to see or touch her child after birth so the baby was left to the care of the ailing grandfather" the grandfather who made the necessary arrangements with women in the neighborhood, right? right? OR THAT GREAT OFFENDER "A newborn baby was left on the doorstep and they brought it in and took care of it no issues" What Are You Going to Feed That Baby. Hello?

Like. It's not impossible, but arrangements are going to have to be made. There are some logistics.

[cryptocism]

that half-blank, half-apocalyptic look

"i can b ur angle or yuor devil" etc etc "get a man who can do both" etc etc

obsessed with this vamp i think he should get to do whatever he wants forever

[wearenotjustnumbers2]

Reminder that Palestinians in Gaza are being deliberately starved by Israel. Families in gaza are boiling plant leaves and eating them. They're also eating animals and birds food to stay alive. There are reported cases of kids and infants who died out of hunger and/ or cold. Starving people is part of genocide too. Remember how fast medicine was provided for the Israeli hostages, while Palestinians are starving for food and water and getting operations and amputations performed with no medication or anesthesia whatsoever.

[cocklessboy]

The other day I told a friend of mine that I never forget to take my ADHD meds because I fucking love my ADHD meds. I'm in my late 30s, I didn't finally get a diagnosis and meds until less than two years ago, and they have changed my entire life.

And he raised his eyebrow at me. We'd been discussing addictive medications a few minutes before, like the Tramadol I finally got from the pain specialist to take once a week or so to give me a break from my chronic pain, so I reassured him that methylpenidate (Ritalin/Concerta) is not addictive (at least not in people with ADHD).

His response? To raise his eyebrow even harder and say "Well it sure SOUNDS like it's addictive!"

And I had to explain to this man - who works in a healthcare related job by the way - that just because medication makes you feel good and helps you, just because you look forward to taking it, that doesn't make it addictive or dangerous. And he wasn't convinced.

The simple fact that I was excited to take a daily pill that has literally changed my life, after decades of fighting to get that medication, made him think I shouldn't be taking it so often. That it must inherently be dangerous.

I'm not even in America, but I'm pretty sure this attitude began there and then spread over here to Europe. This Puritan idea of "if something feels good, you must beware of it. Pleasure is dangerous, it is sinful, it is addiction, it is evil."

I know too many people who subconsciously believe that pleasure = addictive = dangerous = bad. Joy is a slippery slope to hell.

So here is your reminder for today that you don't need to be afraid of feeling good. If something improves your life, use it. Even if it is addictive - learn what that addiction means, whether the addiction is inherently dangerous or not, and whether the benefits outweigh the drawbacks and risks.

My ADHD meds are, in fact, not addictive. But I will take them every day because they make my life orders of magnitude easier. I will enjoy them every time I take them.

My tramadol is addictive. I will still take it. I will keep it on a schedule to avoid becoming addicted, primarily because addiction in this case would mean reduced effectiveness. But I am not afraid of my painkillers. They are life changing.

Take your meds, everyone. Don't let anyone scare you away from doing something that improves your life.

[reasonsforhope]

"The first modern attempt at transferring a uterus from one human to another occurred at the turn of the millennium. But surgeons had to remove the organ, which had become necrotic, 99 days later. The first successful transplant was performed in 2011 — but even then, the recipient wasn’t immediately able to get pregnant and deliver a baby. It took three more years for the first person in the world with a transplanted uterus to give birth. 

More than 70 such babies have been born globally in the decade since. “It’s a complete new world,” said Giuliano Testa, chief of abdominal transplant at Baylor University Medical Center.

Almost a third of those babies — 22 and counting — have been born in Dallas at Baylor. On Thursday, Testa and his team published a major cohort study in JAMA analyzing the results from the program’s first 20 patients. All women were of reproductive age and had no uterus (most having been born without one), but had at least one functioning ovary. Most of the uteri came from living donors, but two came from deceased donors.

Fourteen women had successful transplants, all of whom were able to have at least one baby.  

“That success rate is extraordinary, and I want that to get out there,” said Liza Johannesson, the medical director of uterus transplants at Baylor, who works with Testa and co-authored the study. “We want this to be an option for all women out there that need it.”

Six patients had transplant failures, all within two weeks of the procedure. Part of the problem may have been a learning curve: The study initially included only 10 patients, and five of the six with failed transplants were in that first group. These were “technical” failures, Testa said, involving aspects of the surgery such as how surgeons connected the organ’s blood vessels, what material was used for sutures, and selecting a uterus that would work well in a transplant. 

The team saw only one transplant fail in the second group of 10 people, the researchers said. All 20 transplants took place between September 2016 and August 2019.

Only one other cohort study has previously been published on uterus transplants, in 2022. A Swedish team, which included Johannesson before she moved to Baylor, performed seven successful transplants out of nine attempts. Six women, including the first transplant recipient to ever deliver a baby back in 2014, gave birth.

“It’s hard to extract data from that, because they were the first ones that did it,” Johannesson said. “This is the first time we can actually see the safety and efficacy of this procedure properly.”

So far, the signs are good: High success rates for transplants and live births, safe and healthy children so far, and early signs that immunosuppressants — typically given to transplant recipients so their bodies don’t reject the new organ — may not cause long-term harm, the researchers said. (The uterine transplants are removed after recipients no longer need them to deliver children.) And the Baylor team has figured out how to identify the right uterus for transfer: It should be from a donor who has had a baby before, is premenopausal, and, of course, who matches the blood type of the recipient, Testa said...

“They’ve really embraced the idea of practicing improvement as you go along, to understand how to make this safer or more effective. And that’s reflected in the results,” said Jessica Walter, an assistant professor of reproductive endocrinology and infertility at Northwestern University Feinberg School of Medicine, who co-authored an editorial on the research in JAMA...

Walter was a skeptic herself when she first learned about uterine transplants. The procedure seemed invasive and complicated. But she did her fellowship training at Penn Medicine, home to one of just four programs in the U.S. doing uterine transplants. 

“The firsts — the first time the patient received a transplant, the first time she got her period after the transplant, the positive pregnancy test,” Walter said. “Immersing myself in the science, the patients, the practitioners, and researchers — it really changed my opinion that this is science, and this is an innovation like anything else.” ...

Many transgender women are hopeful that uterine transplants might someday be available for them, but it’s likely a far-off possibility. Scientists need to rewind and do animal studies on how a uterus might fare in a different “hormonal milieu” before doing any clinical trials of the procedure with trans people, Wagner said.

Among cisgender women, more long-term research is still needed on the donors, recipients, and the children they have, experts said.

“We want other centers to start up,” Johannesson said. “Our main goal is to publish all of our data, as much as we can.”"

-via Stat, August 16, 2024