#I have All The Electrolytes in supplement form

[tj-crochets]

Hey y'all! The AC in my house is like half-broken and I have all the heat tolerance of a particularly sad penguin*, so I could use some advice. I am from a desert area, so I know the stay hydrated, electrolytes, loose clothes type advice, but do you have any advice for handling the heat in humid areas specifically? Also, does anyone have any recommendations for sun hats? Specific sun hats you recommend are what I'm looking for, but if you don't have a specific one an idea of what criteria I should look for would be very helpful too *I say this jokingly, idk how much heat tolerance penguins actually have. I have POTS, salt wasting syndrome, and some unknown autoimmune issue that probably involves my endocrine system? Docs are still working on it but the sum total is I cannot exist in hot temperatures

[lizzyscribbles]

Okay but can we talk about the amount of electrolytes (sodium specifically) that Bakugo must need to consume to exist??

Weird thing to fixate on, I know, blame my degree, but think about this: His quirk relies on his ability to sweat, which means the more he sweats the more he can use it. The main thing you lose when you sweat is water and sodium, the longer you sweat, the more those leave your body, that's common sense. Sodium helps you retain water and maintain the fluid balance inside and outside your body, which is why you see it hanging out with water so much and why it's such an important electrolyte that gets lost easily. Yes, technically, you also lose magnesium and potassium, but you lose less of those in sweat than sodium.

Most people don't actually need to supplement electrolytes, even those who exercise regularly, (this is excluding those with illnesses, just considering the average person here), you can get what you need from plain water. Even some athletes don't necessarily need to, it tends to depend heavily on how long you exercise, which is why you see people who do ultramarathons or ironmans downing them. There's ways to test whether or not you actually need them, but suffice it to say, more often than not, just drinking normal water is perfectly fine.

But Bakugo?? There's no way that boy doesn't burn through sodium like it's a fucking competition.

See, the key to whether or not electrolyte supplementation is needed is often found in how long you exercise for, as well as the environmental conditions. Say, if you're exercising outside in the spring for like, thirty minutes to an hours, just water is going to be all you need. Contrast that with a hero course student who likely exercises excessively, multiple times a day, every day, and has a quirk that relies on sweat. That is a recipe for ✨disaster✨ and you know what I don't see on his, or LITERALLY ANY OTHER HERO'S, costume??

A WATER BOTTLE.

I don't care if it ruins the aesthetic you're going for, dude, get a freaking water bottle and some little electrolyte packets before you pass out. How have any of these kids not thought of having some form of water on them while hero-ing?? Like y'all gonna be out on patrol for HOURS without any source of hydration? What a great way to die!

Honestly though, how many times do you think Bakugo just keeled over as a kid? Like dehydration can be a sneaky little shit, and with a quirk like that I'm sure they became besties.

Honestly, I wonder if he does actually carry electrolyte drinks and packets around with him because of that. Like, Izuku had to drag his ass back home too many times while they were out playing as kids and he got tired of it so he spent forever researching different electrolyte brands and sleuthing out which had the best water to sodium to sugar ratio (because you do want some sugar in your electrolyte drinks, the sodium uses it as a quick transport to get where it needs to go) for optimal rehydration. And now he's like, hyperaware of the symptoms and anytime his classmates look even a tiny bit like they might be dehydrated he just storms up and starts throwing electrolytes at their face like:

"DRINK YOUR WATER YOU IDIOTS, DO YOU WANT SURVIVE THE FUCKING LEAGUE OF VILLAINS JUST TO DIE OF DEHYDRATION?? THAT'S FUCKING PATHETIC. SIT DOWN AND DRINK THAT BEFORE YOU PASS OUT, DUMBASS."

All while violently shaking a water bottle with the electrolyte powder to shove down their throat.

Aggressive love, yk? At least he's trying.

[orchidyoonkook]

I'm the anonymous person from before..

I won't get into too much details about my personal conditions so I'm only giving enough details for you to know my remedies for migraines that might help. But, some remedies, you have already done by now.

So I severe from migraines a lot. And because I'm autistic, I've always had many migraines because of sensory overload type situations that would last days and even a week. Depends on the situations though.

Some of these are my "remedies" for my migraines.

Laying, even sleeping if that sleeps, in the darkest room you have so I would suggest covering your windows if you need to darken the room to make it less bright. Laying with an eye mask might help with that.

Ice. I recently got this icepack that's like wearing an eye mask, and it's giving enough pressure to your whole head (without hurting you) that tends to seem relaxing. But I don't think you have that. So you ice, ice packs, on your head and neck. Wearing the ice around your ice would be more effective than one your head from my personal experiences.

Drinking water. Coconut water, if you could actually be able to drink it since not everyone enjoys the flavor, is the real water that actually will help hydrate you faster. Mineral waters like fiji could help since lots of those waters have electrolytes. Maybe consume salty foods like soup or chips, or even a pinch of salt on your tongue, just to keep the water in your body. Since not everyone knows salt retains the water in body.

Ibuprofen. Or whichever medicine you usually take.. I would have said to try taking turmeric? Turmeric helps with head and body pains if it's a more holistic approach. Maybe add to your food? Supplements?

Bathing. Warm, or even hot, baths and showers. A hot salt water bath could help? Or just a regular hot shower. Not everyone knows a warm water may actually help with migraines. Since showers and baths are considered to be forms of heat therapy for migraines. They say that among other heat-related remedies, a warm shower has the power to stop pain signals from traveling to the brain and increase blood flow, which can help soothe muscles.

Eating. Because sometimes lack of eating causes migraines too.

Don't know if I missed anything? I was trying to think of my remedies.

Let me just say that I love you so much. I’ve only started getting migraines in the last 5-7 years so it’s still “new” to me.

Just wanted to start off saying thank you thank you thank you. I’m currently undiagnosed but very likely to be autistic as well and it’s only really presented itself fully in the last few years, meaning I’ve always had it, obvi, but I only recently started unmasking. So just learning that that could be a cause is something new and so super useful.

As for the dark room and laying down. I spent about 70% of the last two days sleeping and lying down hoping it would help. And it did a little bit.

The dark room is usually what I do for my severe migraines. I lock myself in my bathrooms and put a towel at the bottom of the door.

Ice is something I never thought about! I’ll have to go get some ice packs!!! I have a heat pad but no ice packs.

If I plug my nose I can drink coconut water but I’ve been guzzling all weekend I can promise you that ♥️.

I don’t have ibuprofen on hand but I did take a shit ton of acetaminophen and it unfortunately did nothing. however I’ve never tried tumeric so I will have to keep that on hand as well!!

And a shower was actually one of the first things I tried because I know it always helps. And it did. But I can’t stay in the shower for 48 hours :(. Stupid being a land mammal and the powers that be charging for a fundamental human right.

I had a really yummy dinner last night that my partner made me for eating. It was a big helping of chicken pasta Alfredo. I want to think it helped but I honestly couldn’t have told cause I felt a little nausea every time I took a bite. But it was so so good.

Hon if you’re missing anything I can’t say anything but thank you for the things that you did remember. I’m gunna keep this ask for later when I inevitably get another one because this has been so incredibly helpful.

Thank you thank you thank you so much truly ♥️♥️. You’re a good human. I hope you know that.

[anotherfauxredhead]

The Post-Bisalp Diaries, Part Two: Survival Of The Tubeless

Happy Two Week Anniversary of me noping the fallopes!

When I was reading up on how others managed post-Bisalp before my own surgery, I saw suggestions like "take Gas-X for bloating", "use stool softeners so you don't 'strain' yourself", "have a heating pad for the shoulder pain", and so forth. They sounded helpful, and it was a good thing I had that stuff already on hand (for other reasons).

That said, here's what really helped me out during my recovery. ***DISCLAIMER*** Your mileage may vary, all bodies are different, and I sure as shit am no doctor or medical practitioner!

*Turmeric-Curcumin Pills*

It's what I first turn to when I get crap like PMS cramps or headaches. I do have ibuprofen on hand, but it's more of a last resort remedy for me. The ones I've been taking post-surgery are Gaia Herbs Turmeric Supreme, but I also have Terry Naturally's Curamin (regular strength) pills.

*CBD Stuff*

Thank goodness I live in a state where CBD products are legal to own. Tinctures and gummies, particularly the ones from Lazarus Naturals, have been a godsend.

*Probiotics*

I still took probiotics pre-surgery, albeit in food form (yogurt, sauerkraut, etc.) since I couldn't have supplements then. When I learned that I was given antibiotics during my surgery, I knew I needed to take probiotics later in the day; it's what balances out your digestive system after the antibiotics fuck with it. Maybe it could explain why, even if my appetite was reduced for the first few days, I didn't have bad gas. I took a high-dose probiotic (think the pills with over 40+billion cultures) in the first week, then, for the second week, went down to probiotics with no more than 25 billion cultures. And some low-sugar yogurt.

*Pedialyte Pops*

Like with many others who had a Bisalp, sore throat is a common post-surgery symptom. (It's the result of having a breathing tube down your throat during the procedure.) Though I had regular popsicles on hand, I ended up buying Pedialyte Freezer Pops as well as they also have electrolytes in them. And they're also fairly low sugar!

*Thrift Stores*

So I had to change up my wardrobe a bit for my recovery. A month leading up to my surgery, I got some jumpsuits, loose, high waisted pants with a comfortable waistband, slip-in shoes so I don't have to bend over and tie my shoes, and even a bed rest pillow in case I felt like a lazy-ass. Thanks to thrift stores, I got all that for a bargain. Who the fuck needs Wal-Mart?

By the way, because of my need to be active, and me fighting the fatigue during the first few days of recovery, I didn't use that bed rest pillow. I guess I may need it down the road, and it only cost me $5.

*Eating Low-Carb, Minimally Processed Foods*

Having been on Keto for the past few years, the diet has not only helped me shed blubber, but I've become more active from it. I can't say if eating low-carb/sugar-free foods and minimally processed foods helped my body heal quicker, but, save for the first three days after surgery, I never felt sluggish in my recovery.

*A Decent Landlord & Loan Deferments*

OK, forget the physical aspects of my recovery; it's the financial aspects that took the real beating. I'm able to receive Short Term Disability while out from work (I do not work from home and my job is very physical), but waiting for the payments have become a pain in the clit. I'm still waiting for them, and it just happens to be a holiday weekend right now. Just my luck! So, I like to give a shout-out to my landlord who was cool with me underpaying my rent for this upcoming month, and the few loan companies who I have accounts with that were able to postpone my payments so I don't go so broke to where I need to sell my sterilized ass on the streets for a few bucks. (Like, literally a few bucks--it's the going rate for old millennial ass.)

Also, a friendly reminder that just because one is childfree doesn't mean they got deep pockets. Some of those "I got to vacation in Italy last week 'cause I got no kids!!!!" posts you see on Reddit's Childfree subreddit are likely made-up as hell (it's Reddit, after all). Now that I think about it, I think I'm more of a WINK (What Income? No Kids) instead of a SINK at the moment.

A Few Things I Got/Have That I Didn't Need In The End...

--GasX pills (I was never really gassy, and they were the 99-Cent Store version as opposed to the name brand, so I didn't lose money on that)

--Shoulder/Heating Pad (others have suggested it, but I only used it just once and that was because it was a cold night)

--stool softeners (I think the probiotics helped me out with this one)

--ibuprofen (took it once and it fucked with me. I'm used to the 200mg pills, but 600mg per pill?! Fuck no!)

--prescribed oxycodone (didn't even open that shit)

And A Couple Things You Don't Need To Buy...

--disposable underwear (the hospital will provide you with as many pairs as you need. I never bled, thankfully, but I was still given a few pairs.)

--anti-nausea patch (another thing the hospital will give you, but only if you request it. I could've saved myself $6 from the pack of anti-nausea patches I bought on eBay! *punches air*)

*****

Again, what helped me out post-Bisalp may or may not help the next person in recovery. If there's one thing I highly recommend that will help the next person recover from a Bisalp smoothly, it's having plenty of money so you don't have to worry about financial shit like me.

**ETA: Tumblr told me this is my 100th post here. I'd celebrate but I also outed myself as a broke bitch in the post, so...

[freyasfolly]

I am increasingly annoyed at the state of my healthcare and wondering what the actual hell is going on at my doctor's office.

In January, combination of dehydration and infection meant I had a surprise ER visit, where I learned I was a little low on potassium as well, and keep an eye on that.

No problem, I kept that in mind as I was grocery shopping, thought it was fine.

Two weeks ago I fucked around with my caffeine intake and Found Out in the form of chest pains, as well as some heart issues, which lead to a holter monitor for a few days, a chest x-ray, bloodwork, all sorts of fun things as they determined if I was having mini heart attacks or not. Everything came back fine, but I was never told 'well, come in to do more tests to find out if you're actively dying'. Meanwhile, I got desperate enough to pick up a potassium supplement as a hail Mary, hoping that an electrolyte imbalance was the cause of my problems.

And it looks like it was, because despite never having been told this from my bloodwork at this latest doctor's visit, the chest pains cleared up almost immediately and the heart stuff shortly after that.

And I still haven't heard back from my doctor's office, so either they assume that I'm not dying and I'll be fine so no need to talk to me, or they just aren't bothering to let me know what they're looking into.

[catsnuggler]

The "ick"post really grinds my gears.

I'm not the tallest man on earth. I'm not the heaviest man on earth.

I'm also over 6 feet tall, if only by a bit. I'm also a little over 200 lbs.

Regular ocean waves *won't* bowl me over. But why would a shorter, lighter man be worth less as a human being, simply for being somewhat more susceptible to ocean waves? Is he going to spend his whole life in those waves? Is he always going to be bowled over by waves? Is that all he is? Someone bowled over by the waves?

That said, I am not the man, though I feel pity and solidarity for him. No, I'm the man who would carry a water bottle.

Remember: I am over 6 feet tall, and I am over 200 lbs - about 205, 210 last I checked. I have significant body mass, and I have a large surface area. The heat affects me tremendously. If I have to stay out in the heat for a long time, and I have water, I might go through bottle after bottle of water, sweating and sweating it all out, and I may not have to urinate, for hours, because the water comes out in the form of sweat before it could ever possibly pool in my bladder enough that I'd have to pee. I also need lots of electrolytes, because I sweat so much that, good as water is, I get heat migraines from electrolyte loss unless I supplement my water with electrolytes, and drink a lot. It wasn't my choice to live in the desert, and my body is certainly not made for desert survival (thank you, Scottish genes, for preparing me to live in the Scottish uplands, when, aside from my dad's brief stay in the UK for a few years as a kid, my family hasn't been anywhere in Europe for centuries, too busy being damn colonizers on a land that deserves better than this, and had the bright idea of moving to hotter and drier places that aren't bad places, but are places we physically do not do well in). Nonetheless, I am in the desert, and I must deal with the heat as best I can, when exposed to the elements.

Yet adapting to circumstance is... "ick". What is this "ick"? "Disgusting"? "Weak"? "Inferior"? "Unattractive"? "Embarrassing?"

I am sure my dry, bloated, rotting body, dead from heat and dehydration, would, on the contrary, be ruggedly handsome, masculine, and sexy. Huh? Don't you want to fuck the dead body of a man who died from the heat, because he valued his masculinity enough not to carry a water bottle?

Disgusting. Such judgment is the true "ick".

[healthcar]

HerpaGreens Reviews - WARNING! I Tried This Herpa Greens For 30 Days!

HerpaGreens is a dietary supplement that claims to be effective in treating and preventing herpes outbreaks. The product is formulated with natural ingredients that work together to boost the immune system, reduce inflammation, and fight off the herpes virus. This article will provide an in-depth review of HerpaGreens, examining its ingredients, benefits, and potential side effects, as well as customer reviews and pricing information.

What is HerpaGreens?

HerpaGreens is a dietary supplement that is formulated to help treat and prevent herpes outbreaks. The product is designed to work by boosting the immune system and reducing inflammation in the body, which can help prevent the herpes virus from replicating. The supplement is made with natural ingredients, including fruits, vegetables, herbs, and spices, which are believed to have antiviral and immune-boosting properties.

According to the manufacturer, HerpaGreens is a safe and effective alternative to traditional herpes medications, which can cause a range of side effects and may not be effective for all patients. The supplement is also said to be easy to use, as it comes in a convenient powder form that can be mixed with water or added to smoothies or other beverages.

HerpaGreens Ingredients

HerpaGreens is made with a blend of natural ingredients that are believed to have antiviral and immune-boosting properties. Some of the key ingredients in the supplement include:

Spinach: Spinach is a nutrient-rich leafy green vegetable that is high in antioxidants, vitamins, and minerals. It is believed to have anti-inflammatory properties that can help reduce inflammation in the body and boost the immune system.

Broccoli: Broccoli is another nutrient-rich vegetable that is high in vitamins, minerals, and antioxidants. It is believed to have antiviral properties that can help fight off the herpes virus.

Tomato: Tomatoes are high in antioxidants and are believed to have immune-boosting properties. They are also believed to have antiviral properties that can help prevent herpes outbreaks.

Ginger: Ginger is a spice that is known for its anti-inflammatory and immune-boosting properties. It is also believed to have antiviral properties that can help fight off the herpes virus.

Green tea: Green tea is high in antioxidants and is believed to have immune-boosting properties. It is also believed to have antiviral properties that can help prevent herpes outbreaks.

Turmeric: Turmeric is a spice that is known for its anti-inflammatory and immune-boosting properties. It is also believed to have antiviral properties that can help fight off the herpes virus.

Garlic: Garlic is a natural antibiotic that is believed to have antiviral and immune-boosting properties. It is also believed to have anti-inflammatory properties that can help reduce inflammation in the body.

Spirulina: Spirulina is a type of blue-green algae that is high in protein, vitamins, and minerals. It is believed to have immune-boosting properties that can help prevent herpes outbreaks.

Reishi Mushroom: Reishi mushroom is a type of mushroom that is believed to have immune-boosting properties. It is also believed to have antiviral properties that can help fight off the herpes virus.

Coconut Water: Coconut water is a natural electrolyte that is believed to have immune-boosting properties. It is also believed to help reduce inflammation in the body.

[d3nt4l-d4m4g3]

Do you know if supplemental estrogen has the same level of harm for men as testosterone does for women? My cursory impression is that testosterone supplementation is much more deleterious for women's health in the long run, which just evidences the misogyny and female erasure in the movement. Estrogen has protective effects and been implicated in why women live longer on average. What are your thoughts? Signed, a radfem lurker who really appreciates all that you do :)

hey dear lurker!

yes, i'd say testosterone in women is more harmful as a rule than estrogen in men. in the cursory research I did, there aren't the same reports of chronic, debilitating pain in trans women as there are in trans men. However, that doesn't mean estrogen is without risks.

If you read my post about testosterone in the female body, you would see that testosterone lowers Ki67 levels. Ki67 is the protein that increases as cells prepare to divide. Dangerously low levels (as seen in FTMs) probably mean the cells aren't multiplying at all, leading to atrophy. Dangerously high levels means the cells are multiplying out of control, leading to cancer. Estrogen stimulates Ki67 levels. Estrogen is a known carcinogen.

In this study of 2260 trans women, it was found that the MTFs are 46 times as likely as their unmedicated counterparts to develop breast cancer. However, they were still not as likely to develop breast cancer as females.

The other major risk that stands out is cardiovascular. most pronounced is the increased risk of venous thromboembolism, the definition of which is:

is a condition in which a blood clot forms most often in the deep veins of the leg, groin or arm (known as deep vein thrombosis, DVT) and travels in the circulation, lodging in the lungs (known as pulmonary embolism, PE).

here is a table from this study that I will explain.

"expected cases" (ECs) means the control group, i.e. the risks of cardiovascular events in undrugged women and men respectively. The standardized incidence ratio, or SIR, is taken by dividing the number of observed cases (OCs) with the number of expected cases. a SIR under 1 means the incidence of a cardiovascular event is lower in trans women than in the control groups. a SIR above 1 means the incidence is increased.

For MTFS, the SIR is comfortably above 1 for both stroke and venous thromboembolism when compared with the male control group. (we can also see that for trans men, the SIR for myocardial infarction (heart attack) is very high, but that's for another post)

That means they are at higher risk for those cardiovascular events.

Now, because trans people are prone at higher incidences to "psychosocial stressors and smoking", synthetic hormones are probably not the only factors in the increased risk of cardiovascular events. But it's safe to say they are a major factor.

This study documents pain in MTF and FTM individuals after they've started cross-sex hormones.

(again, tangent— 61.5 PERCENT FTMS EXPERIENCED CHRONIC PAIN. OVER HALF. )

But MTFS also had a significant rate of chronic pain at 29.8 percent. they reported headaches, "breast" tenderness, and musculoskeletal pain. They also reported that the pain got worse as hormone "treatment" continued. it is also worth noting that testosterone dulls pain, meaning that MTFS on t-blockers and estrogen will be experiencing pain at a level and type that they've never felt before, which I can imagine is alarming. They also tend to be sexually impotent, prone to depression (as T is a mood stabilizer), and can suffer from lethargy, brain fog, and sleep disturbances off T, which can be partially attributed to the diuretic and anti-androgen Spironolactone.

here is a list of side effects of Spironolactone, link here:

(mild)

diarrhea and abdominal cramping

nausea and vomiting

high potassium levels

leg cramps

headache

dizziness

drowsiness

itching

(severe)

Allergic reactions. Symptoms can include:

skin rash

hives

fever

trouble breathing

swelling of your lips, mouth, tongue, or throat

Electrolyte and/or fluid problems. Symptoms can include:

mouth dryness

extreme thirst

extreme weakness and tiredness

fast heart rate and dizziness

not being able to urinate

Dangerously high potassium levels. Symptoms can include:

muscle weakness

not being able to move your legs and arms

extreme tiredness

tingling or numb feeling in your hands or feet

slow heart rate

Breast enlargement (gynecomastia). Symptoms can include:

growth of breast tissue in males and females

Severe skin reactions. Symptoms can include:

redness, blistering, peeling or loosening of your skin, including inside of your mouth.

now, most of these effects probably have low incidence rates, but the sheer number of effects leads me to think—if you're on this drug, there's a good chance you've got a handful of side effects. most of them are relatively harmless and some of them are debilitating.

I would throw in some testimonials from reddit, but r/mtf has recently been privated. It seems they felt it was necessary to have a safe space for males where they could talk about issues that pertain exclusively to them. I wonder why the same measures have not been taken for r/ftm. I wonder.

So, in conclusion, trans women do have an increased risk of cancer, cardiovascular events and chronic pain, and the drugs they take may have a range (a rainbow, even!) of nasty side effects. But chronic pain is nowhere near as guaranteed in trans women as in trans men.

edit: a couple of these studies are behind paywalls. I used sci-hub to access them.

[creekfiend]

Btw, these are fucking amazing. Never have to drink gatorade again!!!!! The Salt Sticks company realized a ton of ppl with autonomic dysfunction were using their electrolyte capsules to manage their illness, so they formulated a new kind aimed specifically at chronically ill people and the Vitassium Club mentioned on the label here is a list you can get on by filling out an online form, that will give you 20% off every order of Vitassium. You do not need to give proof of diagnosis to get on the club. All you need to do is tell them "yes I have a chronic illness which I need to manage with electrolyte supplements". They don't need a diagnosis name or a doctor's name. It is self reported. SO SIGN UP!!!!!!!

[kingocats]

DISCLAIMER: ABOVE ALL IF YOU HAVE AN EATING DISORDER, THE GOAL IS RECOVERY AND TO GET TO A PLACE WHERE YOU CAN EAT AGAIN! This post is merely a list of advice for what to do in the meantime to not worsen your situation.

Alright so as someone who has dealt with eating disorders since they were 12, I want to offer some potentially life saving advice. Of course the best course of action in an ED is to... not have one but that’s literally impossible. Eating disorders are usually chronic and although they can be managed, they can’t really be cured, so.

What do you do to stay as healthy (or rather as... alive) as possible while dealing with an ED?

1. Drink water!!!! Not diet soda, not coffee, water!! And like... as much water as possible, especially if you have bulimia. Eating disorders leave you dehydrated and though you might be able to go weeks without food, you can only go days without water, so please, keep yourself hydrated!!

2. Take supplements. They don’t have calories but they have essential vitamins and nutrients that your body is lacking. These could keep you from losing your hair, getting deathly ill and even permanently destroying your teeth. If you can’t get vitamins from food, make sure you are getting them in pill form at least.

3. Electrolytes. You can get these in Vitamin water zero. Again, doubly important with bulimia but still very important for anorexia because if your electrolytes become imbalanced you can have a heart attack.

4. This one might be asking too much but if you can manage it, try to eat and keep one very healthy meal a day. I know y'all have safe foods like idk in my case it was sweet potatoes with brown sugar (idfk man) but if you can manage a hearty salad with like chickpeas or something that could make all the difference, just one nutrient dense food to keep your body going. Really the goal here is just to stay as undamaged and alive as possible until you can manage recovery.

5. Brush your teeth and floss after vomiting. If you don’t you will regret it, trust me. 

These are just a few, and I definitely have more, some of which might be too challenging, some which have to do with recovery which is not the point of this post and others that are super specific (like avoid high elevations - try not to go skiing, you WILL have a heart attack if you do this while malnourished) but these are a few important points for now. I think we need to start thinking about eating disorders as addictions where recovery is a painful and terrifying process and sometimes impossible for the addict so while they suffer, they at least deserve the knowledge of how to do so without damaging themselves unnecessarily. I am here (as someone who has had an eating disorder for 16 years and been in a place of recovery for 7 of those years) if anyone wants to talk! And will happily add to this post upon request or if I think of something. To everyone struggling right now, I love you and you will get through this <3

[rayarmat]

A Guide to Outpatient COVID Treatment: Step-By-Step Doctors’ Plan That Could Save Your Life

Recently, Dr. Peter McCullough, MD, of Baylor University Medical Center in Dallas testified to Texas Senate HHS Committee  about how mass media and even some government agencies are silencing clinical outpatient evidence for effective treatment of COVID19 and instead push vaccines only (video shown below).

Treatments like those mentioned by Dr. McCullough can be found in sites like https://c19early.com/ but specifically, McCullough refers to the following Appendix to a document published by Association of American Physicians and Surgeons (AAPSonline.org) as an educational resource. It is based on a paper published in American Journal of Medicine (link), by Dr. Peter McCullough and 22 other clinicians (MDs) and researchers (PhDs).

“Seek early treatment and be your own advocate. All of the physicians contributing to this booklet are  on the frontlines treating outpatients at the first signs of COVID illness. Studies in the US and many other  countries clearly show that patients who are treated within the first 5 days of symptoms have better  outcomes using the combination of medications in the algorithm below.”

COVID-19 hospitalizations and death can be reduced with outpatient treatment.

Principles of COVID-19 outpatient care include: 1) reduction of reinoculation, 2) combination antiviral therapy, 3) immunomodulation, 4) antiplatelet/antithrombotic therapy 5) administration of oxygen, monitoring, and telemedicine.

“For the ambulatory patient with recognized early signs and symptoms of COVID-19, often with nasal real-time reverse transcription or oral antigen testing pending, the following 4 principles could be deployed in a layered and escalating manner depending on clinical manifestations of COVID-19-like illness and confirmed infection: 1) reduction of reinoculation, 2) combination antiviral therapy, 3) immunomodulation, and 4) antiplatelet/antithrombotic therapy. Because the results of testing could take up to a week to return, treatment can be started before the results are known. For patients with cardinal features of the syndrome (ie, fever, body aches, nasal congestion, loss of taste and smell, etc.) and suspected false-negative testing, treatment can be the same as those with confirmed COVID-19. Future randomized trials are expected to confirm, reject, refine, and expand these principles. In this article, they are set forth in emergency response to the growing pandemic as shown in Figure 1 .

Treatment algorithm for COVID-19-like and confirmed COVID-19 illness in ambulatory patients at home in self-quarantine. BMI = body mass index; CKD = chronic kidney disease; CVD = cardiovascular disease; DM = diabetes mellitus; Dz = disease; HCQ = hydroxychloroquine; Mgt = management; O2 = oxygen; Ox = oximetry; Yr = year.

The basic groups of prescription medicines and other therapies used in COVID-19: 

▪ Combination anti-viral medicines started as soon as symptoms occur ▪ Medicines to decrease inflammation, such as corticosteroids (called  immunomodulators) 

▪ Anticoagulant therapy to prevent blood-clots that can cause strokes, heart attacks,  kidney shut-down, and death. 

▪ Non-prescription supportive treatments with zinc, vitamin D, vitamin C, electrolyte  drinks such as Pedialyte, and others. 

▪ Home-based oxygen support, such as with an oxygen concentrator. These machines  are available by physician prescription from home health medical supply businesses and are covered on most medical insurance plans. 

I. Antiviral Agents:  

These must be started quickly at STAGE I (Days 1-5):  

Symptoms include sore throat, nasal stuffiness, fatigue, headaches, body aches, loss of  taste and/or smell, loss of appetite, nausea, diarrhea, fever.  

These medicines stop the virus from (1) entering the cells and (2) from multiplying once  inside the cells, and they reduce bacterial invasion in the sinuses and lung: 

▪ *Hydroxychloroquine (HCQ) with azithromycin (AZM) or doxycycline 

OR 

▪ Ivermectin with azithromycin (AZM) or doxycycline 

Either combination above must also include zinc sulfate or gluconate, plus supplemental vitamin D, and vitamin C. Some doctors also recommend adding a B complex vitamin. 

Zinc is critical. It helps block the virus from multiplying.  

Hydroxychloroquine is the carrier taking zinc INTO the cells to do its job.

An educational resource from The Association of American Physicians and Surgeons (AAPSonline.org) 16 

II. Anti-inflammatory Agents - Corticosteroids (“steroids”): Oral and Nebulized. 

These are started at STAGE II (Days 3-14) to reduce inflammation, the cause of added  damage to the lungs and critical organs. Symptoms include worsening cough, difficulty  breathing, chest heaviness/tightness or chest pain.  

As inflammation damages the airways interfering with normal oxygen-carbon dioxide  exchange, blood oxygen levels drop and people experience loss of focus, drowsiness, confusion, difficulty concentrating, low energy and severe fatigue.  

The exaggerated Inflammation response in COVID further increases the risk of blood clots. 

Prescription medicines and other support added now to Stage I medicines are: ▪ nebulized budesonide to help penetrate the lungs and reduce inflammation ▪ oral prednisone, methylprednisolone, dexamethasone 

▪ colchicine – may also be added to reduce inflammation 

▪ full strength adult aspirin 325 mg to reduce inflammation and risk of blood clots ▪ home oxygen concentrator may be needed to improve oxygen levels (requires  physician prescription) 

III. Prescription Anticoagulants (“blood thinners”):

STAGE III (Day 7 and beyond): Symptoms seen in Stage II intensify. Difficulty breathing becomes extreme, oxygen levels  drop sharply, risk of heart attack or stroke increases. At this point, people are critically ill.  

The medicines to be added to Stage I and II medicines now include: 

▪ Aspirin 325 mg unless told not to take by your doctors 

▪ And/or low molecular weight heparin injections (e.g. enoxaparin [Lovenox]) OR 

▪ apixaban (Eliquis), or rivaroxaban (Xarelto), or dabigatran (Pradaxa) or 

edoxaban (Savaysa) in standard doses for 5 to 30 days 

If these added steps do not lead to improvement, or the patient becomes unstable, a 911  call is warranted for ER evaluation and hospital admission so that more aggressive IV  medications (such as remdesivir, Regeneron, and others) may be considered, and more  intensive ventilation regimens are possible in ICU settings. 

IV. Vitamins, Supplements, and Oxygen.  

▪ Zinc sulfate, gluconate or citrate. These forms are available in pharmacies, health  food stores, and sold online. Zinc sulfate 220 mg provides 50 mg elemental zinc, the  recommended anti-viral dose. Zinc in the form of zinc picolinate form is not  recommended following reports of liver damage and tumors from studies about 20  years ago. Following these reports, the German Commission E that regulates  supplements used in medical practice in Germany banned this form of zinc. 

An educational resource from The Association of American Physicians and Surgeons (AAPSonline.org) 17 

▪ Vitamin D3, preferable in oil in capsules for better absorption. Recommended doses  for anti-viral benefit vary from 5000 IU or more for 5-30 days 

▪ Vitamin C with bioflavonoids for antioxidant, anti-inflammatory effects. Dose  

recommendations from our contributors vary from 1000 mg (1 gram) once or twice  a day up to 4 or more times a day. 

▪ A word about quercetin. Some physicians are recommending this supplement to  reduce viral illnesses because quercetin acts as a zinc ionophore to improve zinc  

uptake into cells. It is much less potent than HCQ as a zinc transporter, and it does  

not reach high concentrations in lung cells that HCQ does. Quercetin may help  

reduce risk of viral illness if you are basically healthy. But it is not potent enough to  replace HCQ for treatment of COVID once you have symptoms, and it does not  

adequately get into lung tissue unless you take massive doses (3-5 grams a day),  

which cause significant GI side effects such as diarrhea.

Control of Contagion

A major goal of self-quarantine is the control of contagion. Many sources of information suggest the main place of viral transmission occurs in the home. Facial covering for all contacts within the home as well as frequent use of hand sanitizer and hand washing is mandatory. Sterilizing surfaces such as countertops, door handles, phones, and other devices is advised. When possible, other close contacts can move out of the domicile and temporarily stay with others not ill with SARS-CoV-2. Findings from multiple studies indicate that policies concerning control of the spread of SARS-CoV-2 are effective and extension into the home as the most frequent site of viral transfer is paramount.

Reduction of Self-Reinoculation

It is well-recognized that COVID-19 exists outside the human body in a bioaerosol of airborne particles and droplets. Because exhaled air in an infected person is considered to be “loaded” with inoculum, each exhalation and inhalation is effectively reinoculation. In patients who are hospitalized, negative pressure is applied to the room air largely to reduce spread outside of the room. We propose that fresh air could reduce reinoculation and potentially reduce the severity of illness and possibly reduce household spread during quarantine. This calls for open windows, fans for aeration, or spending long periods of time outdoors away from others with no face covering to disperse and not reinhale the viral bioaerosol.

Combination Antiviral Therapy

Rapid and amplified viral replication is the hallmark of most acute viral infections. By reducing the rate, quantity, or duration of viral replication, the degree of direct viral injury to the respiratory epithelium, vasculature, and organs may be lessened. Additionally, secondary processes that depend on viral stimulation, including the activation of inflammatory cells, cytokines, and coagulation, could potentially be lessened if viral replication is attenuated. Because no form of readily available medication has been designed specifically to inhibit SARS-CoV-2 replication, 2 or more of the nonspecific agents listed here can be entertained. None of the approaches listed have specific regulatory approved advertising labels for their manufacturers; thus all would be appropriately considered acceptable “off-label” use.

Zinc Lozenges and Zinc Sulfate

Zinc is a known inhibitor of coronavirus replication. Clinical trials of zinc lozenges in the common cold have demonstrated modest reductions in the duration and or severity of symptoms. By extension, this readily available nontoxic therapy could be deployed at the first signs of COVID-19. Zinc lozenges can be administered 5 times a day for up to 5 days and extended if needed if symptoms persist. The amount of elemental zinc lozenges is <25% of that in a single 220-mg zinc sulfate daily tablet. This dose of zinc sulfate has been effectively used in combination with antimalarials in early treatment of high-risk outpatients with COVID-19.

Antimalarials

Hydroxychloroquine (HCQ) is an antimalarial/anti-inflammatory drug that impairs endosomal transfer of virions within human cells. HCQ is also a zinc ionophore that conveys zinc intracellularly to block the SARS-CoV-2 RNA-dependent RNA polymerase, which is the core enzyme of the virus replication. The currently completed retrospective studies and randomized trials have generally shown these findings: 1) when started late in the hospital course and for short durations of time, antimalarials appear to be ineffective, 2) when started earlier in the hospital course, for progressively longer durations and in outpatients, antimalarials may reduce the progression of disease, prevent hospitalization, and are associated with reduced mortality. In a retrospective inpatient study of 2541 patients hospitalized with COVID-19, therapy associated with an adjusted reduction in mortality was HCQ alone (hazard ratio [HR] = 0.34, 95% confidence interval [CI] 0.25-0.46, P <0.001) and HCQ with azithromycin (HR = 0.29, 95% CI 0.22-0.40, P <0.001). HCQ was approved by the US Food and Drug Administration in 1955, has been used by hundreds of millions of people worldwide since then, is sold over the counter in many countries, and has a well-characterized safety profile that should not raise undue alarm. Although asymptomatic QT prolongation is a well-recognized and infrequent (<1%) complication of HCQ, it is possible that in the setting of acute illness symptomatic arrhythmias could develop. Data safety and monitoring boards have not declared safety concerns in any clinical trial published to date. Rare patients with a personal or family history of prolonged QT syndrome and those on additional QT prolonging, contraindicated drugs (eg, dofetilide, sotalol) should be treated with caution and a plan to monitor the QTc in the ambulatory setting. A typical HCQ regimen is 200 mg bid for 5 days and extended to 30 days for continued symptoms. A minimal sufficient dose of HCQ should be used, because in excessive doses the drug can interfere with early immune response to the virus.

Azithromycin

Azithromycin is a commonly used macrolide antibiotic that has antiviral properties mainly attributed to reduced endosomal transfer of virions as well as established anti-inflammatory effects. It has been commonly used in COVID-19 studies initially based on French reports demonstrating markedly reduced durations of viral shedding, fewer hospitalizations, and reduced mortality combination with HCQ as compared to those untreated. In the large inpatient study (n = 2451) discussed previously, those who received azithromycin alone had an adjusted HR for mortality of 1.05, 95% CI 0.68-1.62, and P = 0.83.23 The combination of HCQ and azithromycin has been used as standard of care in other contexts as a standard of care in more than 300,000 older adults with multiple comorbidities. This agent is well-tolerated and like HCQ can prolong the QTc in <1% of patients. The same safety precautions for HCQ listed previously could be extended to azithromycin with or without HCQ. Azithromycin provides additional coverage of bacterial upper respiratory pathogens that could potentially play a role in concurrent or secondary infection. Thus, this agent can serve as a safety net for patients with COVID-19 against clinical failure of the bacterial component of community-acquired pneumonia. The same safety precautions for HCQ could be extended to azithromycin with or without HCQ. Because both HCQ and azithromycin have small but potentially additive risks of QTc prolongation, patients with known or suspected arrhythmias or taking contraindicated medications or should have more thorough workup (eg, review of baseline electrocardiogram, imaging studies, etc.) before receiving these 2 together. One of many dosing schemes is 250 mg po bid for 5 days and may extend to 30 days for persistent symptoms or evidence of bacterial superinfection.

Doxycycline

Doxycycline is another common antibiotic with multiple intracellular effects that may reduce viral replication, cellular damage, and expression of inflammatory factors. This drug has no effect on cardiac conduction and has the main caveat of gastrointestinal upset and esophagitis. As with azithromycin, doxycycline has the advantage of offering antibacterial coverage for superimposed bacterial infection in the upper respiratory tract. Doxycycline has a high degree of activity against many common respiratory pathogens including Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, anaerobes such as Bacteroides and anaerobic/microaerophilic streptococci and atypical agents like Legionella, Mycoplasma pneumoniae, and Chlamydia pneumoniae. One of many dosing schemes is 200 mg po followed by 100 mg po bid for 5 days and may extend to 30 days for persistent symptoms or evidence of bacterial superinfection. Doxycycline may be useful with HCQ for patients in whom the HCQ-azithromycin combination is not desired.

Favipiravir

Favipiravir, an oral selective inhibitor of RNA-dependent RNA polymerase, is approved for ambulatory use in COVID-19 in Russia, India, and other countries outside of the United States.35 It has been previously used for treatment of some life-threatening infections such as Ebola virus, Lassa virus, and rabies. Its therapeutic efficacy has been proven in these diseases. Like, the antimalarials and antibiotics, favipiravir has no large-scale randomized trials completed at this time, given the short time frame of the pandemic. A dose administration could be 1600 mg po bid on day 1, following by 600 mg po bid for 14 days.

Immunomodulators

The manifestations of COVID-19 that prompt hospitalization and that may well lead to multiorgan system failure are attributed to a cytokine storm. The characteristic profile of a patient acutely ill with COVID-19 includes leukocytosis with a relative neutropenia. These patients have higher serum level of cytokines (ie, TNF-α, IFN-γ, IL-1β, IL-2, IL-4, IL-6, and IL-10) and C-reactive protein than control individuals. Among patients with COVID-19, serum IL-6 and IL-10 levels appear even more elevated in the critically ill. As with any acute inflammatory state, early treatment with immunomodulators is expected to impart greater benefit. In COVID-19, some of the first respiratory findings are nasal congestion, cough, and wheezing. These features are due to excess inflammation and cytokine activation. Early use of corticosteroids is a rational intervention for patients with COVID-19 with these features as they would be in acute asthma or reactive airways disease. The RECOVERY trial randomized 6425 hospitalized patients with COVID-19 in a 2:1 ratio to dexamethasone 6 mg po/IV daily for up to 10 days and found dexamethasone reduced mortality (HR = 0.65, 95% CI 0.51-0.82, P <0.001). One potential dosing scheme for outpatients starting on day 5 or the onset of respiratory symptoms is prednisone 1 mg/kg given daily for 5 days with or without a subsequent taper.

Colchicine

Colchicine is a nonsteroidal antimitotic drug that blocks metaphase by binding to the ends of microtubules to prevent the elongation of the microtubule polymer. This agent has proven useful in gout and idiopathic recurrent pericarditis. The GRECCO-19 randomized open-label trial in 105 hospitalized patients with COVID-19 found that colchicine was associated with a reduction in D-dimer levels and improved clinical outcomes. The clinical primary end point (2-point change in World Health Organization ordinal scale) occurred in 14.0% in the control group (7 of 50 patients) and 1.8% in the colchicine group (1 of 55 patients) (odds ratio, 0.11; 95% CI, 0.01-0.96; P = 0.02). Because the short-term safety profile is well understood, it is reasonable to consider this agent along with corticosteroids in an attempt to reduce the effects of cytokine storm. A dosing scheme of 1.2 mg po, followed by 0.6 mg po bid for 3 weeks can be considered.

Antiplatelet Agents and Antithrombotics

Multiple studies have described increased rates of pathological macro- and micro-thrombosis. Patients with COVID-19 have described chest heaviness associated with desaturation that suggests the possibility of pulmonary thrombosis. Multiple reports have described elevated D-dimer levels in acutely ill patients with COVID-19, which has been consistently associated with increased risk of deep venous thrombosis and pulmonary embolism. Necropsy studies have described pulmonary microthrombosis in COVID-19. These observations support the notion that endothelial injury and thrombosis play a role oxygen desaturation, a cardinal reason for hospitalization and supportive care. Based on this pathophysiologic rationale, aspirin 81 mg daily can be administered as an initial antiplatelet and anti-inflammatory agent. Ambulatory patients can be additionally treated with subcutaneous low-molecular-weight heparin or with short-acting novel anticoagulant drugs in dosing schemes similar to those use in outpatient thromboprophylaxis. In a retrospective study of 2773 inpatients with COVID-19, 28% received anticoagulant therapy within 2 days of admission, and despite being used in more severe cases, anticoagulant administration was associated with a reduction in mortality (HR = 0.86 per day of therapy, 95% CI: 0.82-0.89; P <0.001). Additional supportive data on the use anticoagulants reducing mortality has been reported in hospitalized patients with elevated D-dimer levels and higher comorbidity scores.53 Many acutely ill outpatients also have general indications for venous thromboembolism prophylaxis applicable to COVID-19.

Delivery of Oxygen and Monitoring

Because ambulatory centers and clinics have been reticent to have face-to-face visits with patients with COVID-19, telemedicine is a reasonable platform for monitoring. Clinical impressions can be gained with audio and video interviews by the physician with the patient. Supplemental information, including vital signs and symptoms, will be important to guide the physician. A significant component of safe outpatient management is maintenance of arterial oxygen saturation on room air or prescribed home oxygen under direct supervision by daily telemedicine with escalation to hospitalization for assisted ventilation if needed. Self-proning could be entertained for confident patients with good at-home monitoring.

Many of the measures discussed in this article could be extended to seniors in COVID-19 treatment units in nursing homes and other nonhospital settings. This would leave the purposes of hospitalization to the administration of intravenous fluid and parenteral medication, assisted pressure or mechanical ventilation, and advanced mechanical circulatory support.”

This is the group’s statement on vaccines:

“Vaccines in Development: 

Several vaccine models are being investigated for SARS-CoV-2 (COVID-19) including DNA and RNA  vaccines. These vaccines take genetic information from other sources that is introduced into the cells. This  information includes instructions to produce a SARS2-like viral antigen itself, and the immune system then  reacts to it to develop immunity to the virus.  

The most important consideration before approving a vaccine for human use is to make sure that the  vaccine is safe and effective. Developing safe and controlled infection models for humans normally takes many  years of phased testing in the lab and then in humans. Many physicians and scientists have been concerned  that vaccine manufacturers, with government support, are speeding up this process in ways that are not  allowing adequate time for the usual phased testing leading up to human clinical trials. Two vaccine  manufacturers already have voluntarily paused their clinical trials in people due to serious adverse events. 

Currently, there are no RNA-based vaccines approved for human use so it would seem prudent to take  the time needed to ensure safety. Vaccines for RNA viruses are notoriously challenging and difficult to  develop. We still, after all these years since AIDS emerged in the 1980s, do not have a vaccine for the AIDS  virus, or the SARS-1 coronavirus that emerged in 2002-2003, and both are RNA viruses.  

Several attempts have been made to create vaccines for coronavirus and other respiratory viruses but  none of the vaccines have survived the testing phases. The vaccine trials for SARS-1 from 2003, for example,  was shut down because it produced autoimmune hypersensitivity reactions when exposed to the natural virus  after immunization in animal studies.  

Another problem is that the SARS-2 virus has already shown many mutations. Viruses adapt to the  environment to survive. Like the flu virus, it is difficult to predict what mutations will occur and circulate  around the world each season. A new vaccine must be reformulated to adjust to the changing genetic makeup  of the SARS-2 virus.  

Even the best vaccines for flu are only about 30-60% effective. Compare that with an effectiveness for  improvement ranging from 64% to more than 90% in more than 100 new studies showing early, outpatient  treatment with our existing medications described in chapters.  

As research on the vaccine continues, safety and effectiveness are of primary concern. The good news  is there are very safe and effective early treatments already available as we described in Chapter 3. Clearly,  early, home-based treatment has now been so successful and offers so much hope, there is less urgency to  have a vaccine.”

You can sign up to receive the full protocol here: https://aapsonline.org/covidpatientguide/  or find the research paper here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410805/

[no-footprints-in-the-snow]

The Pennywise Saga: Purging, Presents, and Predictable

TRIGGER WARNING: Discussion of disordered eating, and eating disorders.

Well, I figured things would go moderately smoothly because it was the first meeting in 8/9 months. And it did. We were kind, grey rocked, and they were kind. The restaurant we ended up going to didn't have any really healthy options, it was unfortunate, but that was my fault. It was me who chose it because it was the first one that came to mind.

Pennywise suffers from an eating disorder. We all know it. She eats a quarter of a meal, and sends it back. Hides food in her napkin. Plays with her food. Sends it back for too much dressing. She constantly berates the waitress, or tells the waitress to talk to the chef about what's wrong with the meal.

I've been doing Intermittent Fasting. I've lost 75lbs. I've been very mindful of my eating, but I've also gone overboard at many points. Fasting for 20 days straight (still taking vitamins, supplements, electrolytes, only drinking black coffee, water, and green tea). It took telling my doctor telling me that I may end up with hair loss for me to stop. My hair is the only thing I truly think is beautiful about me. It's the one thing Pennywise has always loved, too. Despite it being an auburn during the winter, and a ginger tone during the summer months – she had dyed my hair dark brown since I was nine or so to make me look more like the rest of the family. It took until I was 29 or so to stop the habit.

I carried on like this though and still have been doing this. Restricting harder and harder, fasting for 3-5 days twice a month, and even purging. Eating 300 calories or less a day. Exercising excessively despite my bad ankle (more metal than bone). Wearing a brace so that I can get in 20,000 steps. Now with the brown recluse bite on my upper, inner thigh, I've taken some time off, so as not to irritate the area (at my doctor's advice). Anyway, some doctors say that disordered eating is hereditary in a way. Monkey see, monkey do, I guess. I struggle with it immensely.

I've lost 75lbs / 34kg since mid-December. I quit drinking, ordering out, and did all the above. I was actually kind of excited to show off my weight loss, because she would be... proud. It's weird how the brain, despite knowing, despite being told that she's a narc, despite years of mistreatment, or buying 'goal clothes' for me for every birthday and Christmas ever since I was nine or so. If you don't know what 'goal clothes' are, they're clothes that are sizes too small so that you have to lose weight to fit into them. The only thing that ever fit me was shoes. However, she knew that I'd lost 75lbs, as I was rather proud of that fact, and had texted her about it. She couldn't respond because I had and still have all their numbers blocked, but I wanted to brag a little.

First comment when Pennywise saw me was,

"You look the same as when we saw you last time. I thought you said you lost weight."

It crushed me instantly.

We just continued on, I said nothing, smiled through it, and said our hellos. And of course, in the way my family does, we did our one-armed hugs (and air kisses to the one cheek for the women) -- we have very strict conduct of how we touch one another in our family. We stood our ground and did not allow either of them into the house. Pennywise did ask why she couldn't wait in the house, despite the rules being laid out in plain English the day before. I wouldn't have let her in even if she had to pee. I'd have let her piss herself before I let her in our home. We gave them their Christmas presents, and they gave us ours to take home later on, and headed to the restaurant.

When the waitress came, we all ordered. Pennywise asked for the fries that came with her meal to be put on a separate plate. Only… she didn't. Four times in a row, she asked for gravy to be put on a separate plate. When the waitress looked confused and asked,

"You want gravy on the side?" Pennywise looked confused and my father had to say,

"She means fries. She wants her fries on a separate plate."

Pennywise looking confused, countered with,

"That's what I said."

We all looked at her and shook our heads. She still looked confused, but the waitress accepted it, and we carried on. Perhaps Pennywise is starting to... I don't know. It was almost like a moment of aphasia.

In typical habit, I ordered knowing Pennywise would be watching what I ate. I ordered the 'Lunch Rush' without the soup, just the small salad and half a sandwich.

Only, she didn't watch what I ate.

Today, for the first time in my ENTIRE life (and the ENTIRE time that my husband has known her), she didn't send her food back, hide it in her napkin, and nearly finished everything on her plate. When we got home, I commented on how she actually ate. And even my husband noticed that she actually ate.

It was… Intriguing to watch. To see her actually eat. I know that sounds strange, but after so many years of watching her disordered eating -- it was just... kind of mind-blowing. She didn't watch what I ate. AND she ate. It was... a little confusing and intriguing to BE the one watching instead of being watched.

Then Pennywise discussed how her surgery was coming up, and discussed the nitty-gritty details of it. She spoke while we listened, and that was that.

Of course, she opened her Christmas present when we got back to the car. I got her handmade moccasins from the Native reservation because she always buys herself new ones from a store in the mall.  I thought she'd appreciate the real thing.

The beautiful handmade moccasins I got her from the reservation didn't fit – but I expected that – I got them in my size and for myself (she insists we're the same size - we're not). Nothing I buy her is ever good enough anyway, so I simply planned ahead this time. They wouldn't fit her, or she wouldn't like them, and I'd have to return them. Call me selfish if you want, but she's returned every gift I've gotten her since… well, honestly, I can't remember the last time I got her a gift she kept. So this time, I just planned ahead.

We left after giving them directions, doing our one-armed hugs, and went our own ways. It's not that exciting of a story. I think that Pennywise is suffering from the early signs of dementia. I don’t know how I feel about that. I feel despair. I feel anger that she’ll never remember all the horrible things she did to me. That she’ll never apologize. That her first words to me were to mock my weight despite being 75lbs lighter. I feel sad. I feel some weird form of elation -- that maybe she’ll forget me entirely, and I won’t have to worry about her anymore. Sympathy that she’s got cancer, and clearly showing the signs of dementia. My heart is breaking, and yet... I don’t know. I don’t know HOW to feel. I’m crying as I write this last part out because the emotions are so confusing. I always wished she would just disappear. That my troubles would... go away and distancing myself from my family made my troubles fade. But the fact that she’s actually fading away. That she may not make it through this... I feel... Confused. Broken. Validated. Vindictive. Heartbroken. It was like I made a wish, and it... came true, in the worst way possible. I wouldn’t wish this on my worst enemy or critic, and Pennywise is both of those things. This is not closure. This is not... a happy ending. This is just... an ending, in a way. It’s not over yet, and I’m over-analytical and hypervigilant from years of abuse and protecting myself. I’m still working out my feelings and they are just -gestures vaguely- all over the place. I don’t know how I should feel. When I first found out she had cancer, I just felt... numb. I felt like I should care more. But seeing her face-to-face, and seeing her fading away. Only a glimpse of the woman she’s always been at the beginning of her visit, before she became docile and suffered aphasia with her speech. It... broke me. In a way I can’t explain. Today has been an awful day, really. My emotions are... everywhere, and I can’t grasp any one feeling for long before it morphs into something else.

[incomefender9]

Peptide Chemistry

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Content

Dpc10 Peptide

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Ostarine (mk.

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Yet even after a number of days, I began to understand that my "hunger" was a signs and symptom of regular. Nutrition practices come to be deep-rooted and also we accumulate an internal narrative; "I can not function effectively without morning meal", "I need a coffee to start my day", "If I avoid lunch I obtain a mid-afternoon time-out". I enjoy food and also consume a lot of it, so the suggestion of taking in nothing for 72 hrs was intimidating.

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Collagen Peptides Market 2021-2026 In-Depth Analysis on Key Trends, Leading Players & Revolutionary Opportunities - SoccerNurds

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Posted: Fri, 08 Jan 2021 11:59:28 GMT [source]

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As they are proclaimed as a steroid choice without the side effects, it is not unusual how their appeal is quickly expanding. Such a medication might hypothetically serve at replacing testosterone usage in medical settings, which comes with several damaging adverse effects.

A Bluffers Guide To 2 Of Skin Cares Most Effective Active Ingredients.

The chances of estrogen-related sides and water retention are dramatically reduced, as well. Just as with AAS, stacking prevails with peptide hormones; competitors frequently blend and also match a cocktail of representatives. During an occasion they may additionally supplement this routine with a stimulant. EPO creates a rapid increase in haematocrit (occasionally as much as 60 per cent; normal variety per cent), with measurable rises still apparent 4 months complying with withdrawal of the medicine. This is because new members cells have a lifetime of around 120 days. Nevertheless, the pattern of management taken on by somebody seeking performance-enhancing benefits indicates that the degree of the medication in the blood is practically regularly elevated. This implies that they are damaged down by the acids in the belly, in much the same means as proteins in food throughout food digestion.

In contrast, the 'polar zipper' device refers to hydrogen bonding interactions in between the amino acid side chains on surrounding beta strands.

As a result, allowed ɸ values will be relatively restricted compared to various other amino acids.

In 2019 Vapourtec developed a collaboration in the direction of peptide synthesis with Professor Peter Seeberger as well as his Group at Max Plank Institute, Berlin.

This job has actually been released in the paper revealed instantly below.

The side-chain of proline is covalently bonded to the N of the amino team, so in polyproline, there will certainly be less freedom of turning about the Cα-- N bond than with other amino acids.

In overdose as well as most particularly when a rival has actually come to be dried, physical adverse effects can be harmful. Hyperthermia complying with amphetamine ingestion probably killed Tom Simpson on Mont Ventoux in 1967. Some evidence recommends that chronic stimulant misuse was a contributing consider the death of 1998 Scenic tour de France victor Marco Pantani.

Have a look at our recommendations sheet on Diet for concepts concerning exactly how diet regimen can assist your recuperation. Action pedometers can be bought for around ₤ 15 on Amazon.com, in camping stores like Blacks or from the BHF On-line Store. The inquiry that often occurs is just how much workout should we do? The NHS advises concerning 150 minutes or 2 as well as a half hours of moderately intense workout each week for grownups. In theory individuals taking antipsychotics ought to go for greater than this as they need to offset this additional threat element. One sort of workout that is commonly underestimated is basic activity such as home duties and caring for the garden.

Day one was the hardest-- by 5pm I had a cracking headache, regardless of drinking around six litres of water; I assume it went to the very least partly to caffeine withdrawal. A person suggested consuming a mineral-rich salt option such as Himalayan salt, which replaces the electrolytes cleared out of your body; whether it was a placebo effect or not, the headache soon went away. There's absolutely nothing wrong with hostile weight reduction, but reduced-- or in this situation no-- calorie diets are absolutely not lasting as well as ought to kept an eye on closely. If you are thinking of improving the amount of exercise you are obtaining then it may be a good time to think about enhancing your diet too.

SARMs have comparable effects to low doses of testosterone, however to a lesser degree. An additional among the primary advantages of SARMS is that, unlike testosterone, a lot of them do not get converted into 5α-DHT. On top of that, they do not show up to undertake aromatization right into estrogen which might decrease the occurrence of negative effects such as gynecomastia. At the very least in animal research studies, SARMs have actually shown to partly accomplish this, with compounds such as S1 as well as S4 binding to androgen receptors with high affinity and also demonstrating tissue selectivity.

Peptide-based Cardiovascular Therapeutics Market 2021 The demand for the Market will Drastically Increase In The Future - KSU The Sentinel Newspaper

Peptide-based Cardiovascular Therapeutics Market 2021 The demand for the Market will Drastically Increase In The Future.

Posted: Fri, 08 Jan 2021 09:59:15 GMT [source]

SARMs are a reduced term for careful androgen receptor modulators. To sum up, there are countless advantages you can receive from utilizing RAD140. In order to attain also far better results, experts recommend using RAD alongside various other supplements. It doesn't matter if you make use of supplements or go the all-natural way, the most crucial thing is you're keeping fit. Enhancing muscles is not constantly mosting likely to be easy as well as there is no harm in looking for assistance. Ibutamorenis non-hormonal as well as consequently requires no PCT after the cycle mores than. It is finest made use of in a minimum of a 3 month cycle with dosage raising every month.

Huge doses of caffeine can generate convulsions and stress and anxiety assaults. More seriously, long-lasting amphetamine as well as cocaine usage often causes dependency and also dependancy.

These can assist the professional athlete in escaping detection during regular or check, generally by raising the rate at which the medicine are eliminated from the body. It struck me that our mindset towards nutrition is governed as much by practice as by cravings. We drift through much of our life on auto-pilot, consuming when we generally consume. Norway peptides best buy from direct peptides anticipate picking up breakfast at my neighborhood coffeehouse, and also I was constantly "starving" when I arrived.

Considered that these agents really change exactly how a whole variety of genetics work, it's probably not shocking that the prospective adverse effects from lasting AAS use are considerable and also major. This indicates that lasting users go to much greater threat of experiencing a cardiac arrest or stroke. Unlike stimulants, AAS are taken constantly since they do not have instant medicinal results. They need to be taken over a fairly extended period in order to create substantial impacts on efficiency. Usually, a considerably raising dosage of several AAS is taken several months prior to competition-- a process referred to as 'stacking'-- with a reduction in dosage a month or 2 before an event.

The optimum dosing time for MK 677 goes to night straight before going to sleep. This is a non-peptidic, orally active and also selective agonist of the growth hormonal agent secretagogue (secretion-boosting) receptor. It simulates the action of ghrelin in the stomach, raising growth hormone and also IGF-1 levels, yet does not influence cortisol levels. LGD 4033 a SARM like Ostarine but 12 times as effective at just 1/3 the dose! SARMs are harmless to the liver and have little impact on blood pressure. This eliminates the requirement for preloading and on-cycle support supplements. Consequently, a SARM cycle will inevitably be more economical than a traditional AAS/PH (steroid/prohormone) cycle.

[jewish-space-laser]

I have a chronic illness in which makes me bruise so easy, three things my doc has recommended for bruise relief is 1. Heat compress or even soaking in a warm bath, that helps with blood circulation which helps already formed bruises to break down. 2. Vitamin C since it’s anti-inflammatory, either take supplements or eat Vitamin C rich veggies and fruit. 3. Pineapple, it has anti inflammatory enzymes in it.

Of course things could be different for different people and I’m not a doctor so obviously this is just stuff that I do. Please don’t do anything that makes you uncomfortable before talking to a real doctor. Wishing you all the best and hopefully some relief!!!!

Oh my goodness, thank you so much for this! I’m sorry you bruise easily, that must be a pain. My doctor knows about my condition and we’re working on finding a solution, but for now I just kind of randomly lose consciousness lol. It’s all good though, during the day my brother and his fiance stay with me just in case, and I always load up on electrolytes before driving! Again, thank you so much for this, I’m going to try out as many of these as I can. 

[a-zebra-n-her-servicedog-toad]

As all of you know if you don’t know by now I have a connective tissue disorder called Ehlers Danlos syndrome. I myself have referred to it as the “junk drawer disorder” due to the long list of comorbidities or conditions you can have a long with the primary condition. The definition of Comorbidity noun or plural noun: comorbidities Is the simultaneous presence of two chronic diseases or conditions in a patient.

When I discuss my medical issues many times it’s actually these “comorbidities” I am talking about. Although the majority of my medical issues can be explained by my genetic disease called Ehlers Danlos Syndrome. The majority of the time when I discuss my medical issues I get the looks of disbelief or some have even asked “do you really have all these problems?” The answer to that is simple, it’s yes!

So I decided I’ll list only the comorbidities that I have confirmed diagnoses (dxd) of. During the next couple of months I will discuss these medical problems in more detail.

These are not in any specific order. The list is a Semi-common Comorbidities (Unofficial) list. It's how the article labels it and I think it’s smart to label it this way. Mainly because there currently isn’t any statistics, how common these comorbidities are among EDS patients. The original list can be found at the website at the bottom of this post.

FELLOW ZEBRAS I’d like your input on anything you see that you also experience or have been diagnosed with.

~ Chronic Pain * dxd neuropathy*, neuralgia Myofascial Pain Syndrome* ACNES

~Fibromyalgia*

~Mood disorders dxd Anxiety*, PTSD*, Major Depressive Disorder*

~ irritable bowel syndrome IBS*

~Incontinence* at any age (often from occult tethered cord and/or MCAD or allergy induced) only experienced not diagnosed

~Uterine or rectal prolapse, pelvic floor dysfunction*

~Frequent (seemingly idiopathic) nausea and vomiting (may be from impinged vagus nerve/MCAD/hiatal hernia/gastroparesis/Chiari)

~ Arthritis of all kinds, Osteoarthritis* in the spine, neck and hands, but RA common especially early onset

~ Insomnia* also referred to as “painsomnia”(trouble falling and staying asleep, multiple causes in the EDS patient including pain and hyperadrenergic)

~ Hypotonia (unusually weak muscles despite “training” or physical therapy)

~Dizziness* (with or without syncope)

~Thyroid issues (high and low, often auto-immune despite normal TSH “levels For me Hyperparathyroidism*

~Deviated septum

~Chronic and recurrent sinus infections and sinusitis* (allergy shots have helped this)

~Frequent joint dislocations and subluxations (partial dislocations) or being so-called “double-jointed“ bracing is helping

~ PCOS and menorrhagia (very heavy periods)

~Tendonitis* and bursitis* of all kinds (aka “soft tissue rheumatism”, alt. tendinitis)

~Varicose veins* and spider veins, often early onset, easy bruising*

~Migraines* and headaches of ALL kinds and durations, (often driven by hydrocephalus from MCAD)

~ Strokes* (I had a TIA 2012)

~Mitral valve prolapse* (mine is mild)

~Easy bruising* often from no apparent cause or injury

~GERD* (weak hiatal sphincters and MCAD can contribute here – the stomach produces acid in response to histamine from food reactions)

~Gastroparesis* (slow or no stomach emptying) and dysmotility (poor digestive movement) beyond just constipation and IBS, possibly from impinged nerves & vessels

~Sciatica* (VA lists this as SI Joint Dysfunction

~Bilateral hip dysplasia* (sometimes seen at birth, and later) ability to “pop” – aka sublux – hips out and back in easily, which should be avoided!)

~Malabsorption and malnutrition* and nutritional deficiencies despite diet and even supplementation sometimes. (Poor absorption).

~Electrolyte imbalances* (often low potassium)

~Osteopenia* (low bone density) and osteoporosis* (brittle bones), often early onset

~Hiatal hernia* (stomach to esophagus sphincter) and all other forms of hernias just about anywhere (inguinal, duodenal, abdominal, etc.)

~Costochondritis* (pain at front rib attachment point to sternum)

~Chondromalacia* (cartilage loss) of all kinds, especially patellae (loss of cartilage in the knees, but can occur elsewhere, e.g. hips)

~Frozen shoulder

~Striae* aka “stretch marks” even in males and young (prepubescent) females (i.e. not always associated with pregnancy!)

~Bruxism* (jaw clenching, tooth grinding)

~TMJ* pain and issues, subluxations and dislocations (Temporo-mandibular joint syndrome, jaw alignment trouble)

~Restless Leg Syndrome* (RLS) and leg cramps (often eased by increased magnesium)

~Plantar Fasciitis*

~Chronically low Vitamin D and B12 levels* (caution urged for those with MTHFR mutations with the latter, may need a different form of Vi

Weak or crowded teeth, many need early or partial dentures

~Receding gums*

~Hair loss early, and even in women, especially those with signs of MCAD or iron imbalances

~Deviated septum (misaligned nasal cartilage)

~Trouble swallowing & choking issues, often neuropathic in origin from CCI, sometimes due to floppy laryngeal tissues

~Esophageal spasms (can extend to anywhere along GI tract also)

~Skin tears or rips, trouble suturing, would dehiscence (trouble healing post surgery, especially soft inner tissues)

~Liver problems, including fatty liver and lesions, enlarged liver

~Enlarged gallbladder & spleen, appendicitis (may be MCAD driven)

~Breast Ptosis (sagging, droopy breasts) had surgery to lift and reduce

~Leaky gut syndrome

~Dry eyes and blepharitis (bacterial eyelid infections), as well as retinal tears and more

http://ohtwist.com/about-eds/comorbidities

Remember Stay Zebra Strong!!