#tumor metastasis

[cbirt]

A significant obstacle to the clinical prognosis is tumor metastasis, or the spread of cancer cells from the original tumor to other locations. The current approaches to predicting and detecting tumor metastasis are inefficient and unclear since they rely on laborious tests and subjective clinical judgments. For treatment interventions to be successful and for patients to survive, accurate tumor metastasis likelihood prediction is essential. 

Finding important genes may yield useful information for locating biomarkers unique to each tumor. Using a K-fold cross-validation process, the researchers trained the classification model, and GNNExplainer was used to interpret the projected outcomes. By assessing the model, graph structure contribution, and multi-omics data, MetaGXplore’s efficacy was proven. Lastly, enrichment analysis of differentially expressed genes and pathways was carried out to investigate the biological roles of significant differential genes and the connections between important pathways. 

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[paolastinge]

Medendi non fa per me.

No, grazie: non ci tengo ad avere a che fare con "ricercatori" analfabeti funzionali che negano dignità alle persone offendendo utenti; dicendo ad essi che sono "metastasi" - soprattutto in veste di ricercatori in campo di tumori. Amo i competenti (e non è il caso di Maurizio Scaltriti @ScaltritiLab); @Medendi2.

Siamo quello che facciamo: un "ricercatore" incapace di controllare le proprie azioni scrivendo su un social, (dove si ha tutto il tempo di riflettere), lo è anche sul lavoro - e non avrà alcuna difficoltà a truccare dati di laboratorio.

[medicomunicare]

Battaglia al carcinoma triplo-negativo con attacco alle protein-chinasi: le scoperte su DAPK3

Il carcinoma mammario triplo negativo (TNBC) è il sottotipo di tumore al seno più difficile da trattare. Le pazienti con TNBC rappresentano oltre 20.000 casi di questa condizione ogni anno solo negli Stati Uniti. Hanno esiti peggiori rispetto alle pazienti con altri sottotipi di tumore al seno: il loro tasso di mortalità a cinque anni è di circa il 40%. Si pensa che l’alto tasso di mortalità…

[creativeera]

Bone Cancer Drugs Market is driven by growing demand for targeted therapies

The global Bone Cancer Drugs market is primarily driven by the increasing prevalence of cancer including bone tumor or bone cancer. Bone cancer drugs help in treating cancer that starts in the bones, such as osteosarcoma or Ewing's sarcoma. Bone cancer drugs include molecular target drugs, chemotherapy and others that help inhibit or block the growth of cancer cells. Bone cancer drugs are used for treating primary bone tumors and metastatic bone tumors. Primary bone tumors start within the bones whereas metastatic bone tumors spread to the bones from other parts of the body. Bone cancer drugs block the growth of cancer cells by interfering with cell division or inducing cell death. The increasing adoption of targeted therapies including monoclonal antibodies and small molecule inhibitors are helping treat various types of cancers more efficiently with lesser side effects. The growing prevalence of bone cancer coupled with availability of advanced targeted therapies are the major factors driving the growth of the global bone cancer drugs market.

The Global Bone Cancer Drugs Market is estimated to be valued at US$ 1423.67 Mn in 2024 and is expected to exhibit a CAGR of 5.2% over the forecast period 2024 to 2031. Key Takeaways Key players operating in the Bone Cancer Drugs market are Advaxis, Inc., Cellectar Biosciences, Inc., OPKO Health, Inc., Pfizer Inc., Amgen Inc., Novartis AG, Eli Lilly and Company, Debiopharm Group, Merck Co, Bayer AG, Bristol-Myers Squibb Company, Takeda Pharmaceutical, F. Hoffmann-La Roche Ltd and Teva Pharmaceutical. The demand for bone cancer drugs is increasing globally due to rising prevalence of primary bone tumors as well as bone metastasis. According to cancer research UK, around 2,300 new bone cancer cases are reported each year in the UK. The increasing incidences of bone metastasis from cancers originating in breasts, lungs and prostate is a major factor driving the Bone Cancer Drugs Market Size. According to American Cancer Society, over 170,000 new cases of breast cancer are expected to be diagnosed in 2021 in the US, out of which approximately 40,000 will develop bone metastases. The global companies are expanding their presence into emerging markets of Asia Pacific, Middle East and Latin America to tap the growth opportunities in these regions. Market key trends The Bone Cancer Drugs market is witnessing trend of availability of personalized medicines. With advancement in understanding of genetics and specific mutations driving cancers, targeted therapies are being developed that can identify unique mutations in an individual patient's cancer and target them precisely. This enables delivering the right treatment to the right patient and optimizing treatment outcomes. Companies are investing heavily in development of novel targeted therapies and companion diagnostics that help deliver personalized cancer care. This trend is expected to significantly influence the bone cancer treatment landscape and support market growth over the forecast period. Porter’s Analysis Threat of new entrants: High research and development costs and regulatory barriers related to clinical trials make it difficult for new companies to enter the bone cancer drugs market. Bargaining power of buyers: Patients have limited bargaining power due to serious nature of disease. However, availability of alternative treatment options provide some bargaining power. Bargaining power of suppliers: Established drug manufacturers have significant bargaining power due to their large product portfolios and scarce manufacturing capabilities. Threat of new substitutes: Alternatives like chemotherapy and radiation therapy impose a moderate threat as bone cancer drugs aim to target tumors specifically. Competitive rivalry: Potential for high profits drives major pharmaceutical companies to intensely compete through intensive research and clinical trials. Geographically, North America is currently dominating the bone cancer drugs market in terms of value owing to high prevalence, increasing healthcare expenditure and presence of major players. The market in Asia Pacific is projected to witness the fastest growth over the forecast period due to growing healthcare infrastructure, large patient pool and rising disposable income in developing countries. Another major geographical region concentrated with bone cancer drugs market is Western Europe. Countries like Germany, United Kingdom and France collectively account for highest market share due to well-developed healthcare systems and availability of favorable reimbursement policies.

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About Author:

Ravina Pandya, Content Writer, has a strong foothold in the market research industry. She specializes in writing well-researched articles from different industries, including food and beverages, information and technology, healthcare, chemical and materials, etc. (https://www.linkedin.com/in/ravina-pandya-1a3984191)

[moscanna]

Trasformazione in un albero

Traduzione in italiano della poesia di martedì 12 Marzo. * l’incantesimo é lanciato sono stata trasformata piuttosto rapidamente in un albero ben piantato in un letto . non posso andare da nessuna parte – velocemente . fisicamente circola solo l’energia ora attraverso le radici rami e capelli sparsi ovunque per la stanza . aderirò a questo miracolo nato da una triste fiaba…

[kondavanelos]

Πολλαπλές εγκεφαλικές μεταστάσεις από καρκίνο του πνεύμονα.

[10-dutchies-12-bicycles]

damn wound healing goes crazy fast when u eat a fuckton of vitamin C

[paolastinge]

QUANDO SEI UN ANALFABETA FUNZIONALE, MA FAI IL RICERCATORE. - Medendi non fa per me. (on Wattpad) https://www.wattpad.com/1345620061-quando-sei-un-analfabeta-funzionale-ma-fai-il?utm_source=web&utm_medium=tumblr&utm_content=share_reading&wp_uname=paolastinge&wp_originator=Ui4CAtgGpANH3FKbtAR5ijiLXTrz0Do%2Bh2UbTBxgaBKE5XqvPYscNjauuUurAEf0WOvVMit7cwWYtCEZT5qgyiSFjik8Z73ol7ELGLNuhaJrCF%2BhEG5zMleggX%2Beb4EE L'analfabetismo funzionale è riscontrabile anche fra gli stessi "ricercatori", cioè fra chi si dedica al campo della ricerca scientifica.

[stemk17]

Premio: "è meglio che sto zitto" assegnato a Maurizio Scaltriti.

L'analfabetismo funzionale di Maurizio Scaltriti (@ScaltritiLab su Twitter).

Quali sono i principi della deontologia medica?

1) Rispetto per i diritti e la dignità di ogni persona

2) Competenza

3) Responsabilità

4) Integrità

che non ritroviamo nell'atteggiamento sopra riportato in allegato, e ciò va a discapito dell'autorevolezza della scienza stessa.

[truth4ourfreedom]

THE BENEFITS OF IVERMECTIN. IF YOU HAVE CANCER, FREQUENT COLD OR INFECTIONS, MUSCLE SHRINKAGE, CARDIAC ISSUES, CROHNS, HERPES, ETC.

The study was published in the Cureus Journal of Medical Science.  LET'S TALK ABOUT IVERMECTIN 1 – Ivermectin prevents the damage caused to RNA Vaccines.  2 – Ivermectin blocks the entry of Spike Protein into cells.  So, if the person was vaccinated with COVID, they have hope, they have a way to treat themselves through Ivermectin.  3 – Ivermectin is a treatment after Covid and after vaccination, it is an effective medicine in all phases of Covid 19, even before entering the cell, Ivermectin already destroys the virus in the blood.  It only has beneficial effects and no harmful effects in the treatment of the coronavirus.  4 – Ivermectin has a very powerful anti-inflammatory action against Coronavirus.  5 – Ivermectin has a powerful action for traumatic and orthopedic injuries, it strengthens muscles and has no side effects like corticosteroids.  6 – Ivermectin treats autoimmune ailments such as: rheumatoid arthritis, ankylosing spondylitis, fibromyalgia, psoriasis, Crohn's disease, allergic rhinitis.  7 – Ivermectin reduces the frequency of flu and colds.  8 – Ivermectin improves the immunity of cancer patients.  9 – Ivermectin treats Herpes Simplex and Herpes Zoster.  10 – Ivermectin reduces the frequency of sinusitis and diverticulitis.  11 – Ivermectin protects the heart in cardiac overload, in an embolism for example, it prevents cardiac hypoxia because it stimulates the production of basic energy so that the tissue is not destroyed and thus improves cardiac function.  12 – Ivermectin is antiparasitic.  13 – Ivermectin is anti-neoplastic (anti-cancer), it suppresses the proliferation and metastasis of cancer cells, only killing cancer cells and preserving healthy cells, improving the effectiveness of chemotherapy treatment, as it kills cancer cells resistant to chemotherapy, defeating the resistance to multiple chemotherapeutics that tumors develop, and combined with chemotherapy and/or anti-cancer agents, it provides an increase in the effectiveness of these treatments.  14 – Ivermectin is antimicrobial (bacteria and viruses), and increases immunity.  15 – Ivermectin reaches the Central Nervous System and regenerates the nerves.  16 – Ivermectin regulates glucose and insulin metabolism.  17 – Ivermectin regulates cholesterol metabolism.  18 – Ivermectin reduces liver fat in steatose.  19 – Ivermectin protects the liver exposed to insecticides.  20 – Ivermectin attacks the virus wherever it is, regardless of mutations.  21 – Ivermectin serves for the prevention and treatment of coronavirus, surprisingly.  Unproven efficacy is not of Ivermectin, but of vaccines.  22 – Ivermectin, used as a prophylactic agent, was associated with a significant reduction in infection, hospitalization and mortality rates due to COVID-19.  23 - Ivermectin does not attack the liver, since it is not metabolized in it, and if in the intestine, on the contrary, it protects the liver. 

BIG PHARMA DOES NOT WANT YOU TO KNOW THIS.THEY WANT TO SELL YOU THE EXPENSIVE MEDS THEY MAKE BILLIONS ON.

Please read, save and re-blog before Tumblr takes this down.

[radishblogging]

Daikon and I stayed at my brother’s apartment as he lives in the same town as Daikon’s radiation oncologist…

And today we got great news! There is no sign of metastasis, her lymph nodes are normal, and the CT scan (which was taken for her radiation therapy planning) showed a big empty space where her tumor used to be. Just the medication she takes every day was enough to shrink it down to a fraction of the size it was at diagnosis. Daikon will still do the radiation therapy to catch the last of it but I feel really optimistic that she will beat this and become cancer free for many years. Thank you everyone for your kind words, thoughts, and wishes for Daikon’s good health!

[angels-roses]

A very dear friend has been dealing with breast cancer. The medication took a lot out of her, to the point she wasn’t able to do anything, so she took herself off all the meds and they tried a new treatment. The cancer metastasis and basically went through her whole body. She wasn’t feeling great but she was better, and a year has pasted. Yesterday she came down with a migraine headache and throwing up. It got so bad she called an ambulance, she was admitted to the hospital because she had a stroke. The doctors did more tests and they found a large cancerous tumor in her brain. She now has to have surgery or she could go blind and go into a coma.

She is an amazing person with very strong faith. I’m asking for your prayers to help her deal with the pain, and strength and support for her friends and family .

God Bless 🙏💕

[stanfordswifey]

"I'll be here for you, my love"

Ford Pines x reader

You've been in the hospital for 5 years straight, your cancer developing and spreading. The tumor you had ignored had now developed and evolved, spreading to your organs, causing your stage 1 liver tumor to evolve into stage 4 metastasis.

Just yesterday the doctor walked into your room quietly, it was unusual. She had some news to break to you. "I'm afraid you only have a couple more days left. I've told you this before but its any time now, i'm sorry." You smiled at her, noticing the tear falling down her cheek and frown mentally, keeping a fake strong facade. "It's not your fault. I'm glad you tried your.best and never gavs up on me." Your hand curls into a ball under the sheet, doing your best to sray strong. The doctor left soon after, leaving you alone in the room with only your thoughts, your brain wandered 'will i tell ford?' 'Will he be okay?' 'I hope he's going to be fine without me'

You stared mindlessly at the ceiling, thoughts and memories rolling around in your mind like a film for a movie, you curse at the solidarity of your life, eventually falling asleep. You felt pathetic, worthless even, knowing that your husband too busy to even worry about you.

(You eventually fall asleep and wake up the next day)

It was another dreary day at the hospital, the sight of white boring walls and minimalistic decor making you lose your sanity by the minute, not having anything to suppress the agonizing pain you felt in your body.

-ford's pov-

"It has been a while since I last visited them at the hospital"

He murmurs, to no one but himself.

You've been gone for so long, off he visited you time to time, but ultimately focusing on the portal more and more to distract himself from worrying about you too much.

As he was working on his portal, his phone suddenly rang, causing him to jump at the sudden sound, rolling his eyes as he pushes himself away from the table (yk those chairs w wheels he basically just rolled over to the phone LMAO).

He accepts the call, ruffling his hair in frustration.

"Ford Pines here, who is this?"

"Ah, sorry, I'm doctor may here, what is your relationship to (reader)?"

He hums, fidgeting with a machine part with his fingers

"I'm their fiancé, what's wrong?"

The doctor clears her throat on the other line,

"I'm sorry to tell you, their tumor has started to spread to numerous other organs, I fear they don't have much time left.."

Ford feels his stomach drop, his hand loosening.

".."

"I suggest you get them out of the hospital and just spend time together, I'm afraid there isn't much we can do now. It's best to spend time while they're still here"

"..I see, thank you doctor."

The call ended, he immediately drops his phone and covers his face with his hands, tears falling down. They really couldn't do anything now. He didn't know what to do.

That night he spent his time sobbing, thinking of ways to help you, looking for a cure, a remedy, anything to help you, he failed miserably.

After a couple hours of thinking it over and breaking down he decided to pick you up from the hospital and spend time together, if you couldn't be there for the entirety of his life, atleast he'd be there for yours.

A/N

Hi hi!! This was shitty! I havent written anything for a while T~T please do send me some ideas/requests or if I did anything wrong plz do comment it down, also English isn't my first language so It's not perfect, this will be like 2 or 3 parts? I dont know yet but I will update :33 thank you again for reading <33