#thymine art

[thyminet]

Happy Pokémon Scarlet & Violet day~

[little-devil-child-g]

THEY ARE PONT DE SOUFFRE 🗣️

Here and focusing on life's downsides, Pont De Souffre is a punk band that I based on concepts I learned about in science class 🧬

I decided I would work on their designs in time for Art Fight 💪

Normalsy oc design lore drop coming up:

The name "Pont De Souffre" is inspired by "pont disulfure" or in English, disulfide bridges. It's a French play on words translating to "Bridge Of Suffering" ("souffre" referring to suffering, instead of "soufre" which refers to sulfur).

Gatac Okazi's name and parts of his design are inspired by Okazaki Fragments ("Okazi" being some letters from "Okazaki"). His shoes and accessories are inspired by the Bacteriophage virus. His first name (Gatac) comes from the DNA chemical bases : adenine (A), guanine (G), cytosine (C), and thymine (T). It's also inspired by the title of the film Gattaca, that was named in a similar way.

Nadah's name and design is inspired by cellular respiration (her first name being based off of NAD+/NADHs and her last name being a combination of "Mitochondria" and "Krebs" (referring to the Krebs Cycle specifically)). Her leg warmer and hairpin has car designs because NADHs were compared to taxis that transported electrons and hydrogen and I really liked that comparison lol

Tee-Min's name is based on the DNA chemical base thymine (T), their last name "Ceelyse" is based on cytolysis ("cytolyse" in French), this has also inspired their hair. Their shoes are inspired by agarose gel electrophoresis. Tee-Min's sweater has phospholipid sleeves and a phospholipid bilayer pattern on the torso. Their pants have a pattern referring to bacterial cloning vectors.

I learnt all of this in French originally so if any of the terms are wrong please forgive me 🙏 If you actually read any of this bless your little soul lol

[bhushans]

Unveiling the Power of Data: Global DNA Sequencing Services Market

The global DNA sequencing services market is anticipated to rise sharply and amount to USD 2,080.2 million by 2033. This significant increase from its USD 945.6 million base in 2023 is the outcome of an 8.2% compound annual growth rate (CAGR).

Because they enable the analysis of genetic material and the discovery of variants, mutations, and biomarkers associated with a range of disorders, including cancer, DNA sequencing services are crucial to the field of genomics. These services encompass a broad spectrum of sequencing methodologies and procedures, offering physicians, researchers, and pharmaceutical companies enlightening details on the genetic origins of illnesses and personalized therapeutic strategies.

Empower Strategies With Your Report Sample: https://www.futuremarketinsights.com/reports/sample/rep-gb-6453

The primary driver of the expected growth of the global market for DNA sequencing services is the rising incidence of cancer across the globe. The need for precision medical techniques and state-of-the-art genetic technologies to enhance diagnosis, prognosis, and treatment results is growing along with the global cancer patient population. The use of DNA sequencing services in oncology is being driven by researchers’ and doctors’ ability to define tumors, discover promising therapeutic targets, and create individualized therapy regimens based on individual genetic profiles.

DNA Sequencing: Unlocking the Secrets Within

The order of the four building units of DNA—adenine (A), thymine (T), guanine (G), and cytosine (C)—can be determined via DNA sequencing, a potent technology. Interestingly, A and C always pair with T and G, respectively. Deciphering the base pair sequence is essential to obtaining an individual’s genetic code. This information holds immense potential for various applications, including:

Identifying regulatory instructions within DNA

Pinpointing the location of genes

Understanding the genetic underpinnings of diseases

Top Highlights from the FMI’s Analysis of the DNA Sequencing Services Market: •The North American region is expected to account for the leading market share of more than 40.6% in 2023, followed by Europe, which is projected to account for 32.4% in the same year.

•The United Kingdom is forecast to expand at a CAGR of 12.9% over the estimated period, suggesting significant business avenues that the country is expected to present.

•India is anticipated to record a CAGR of 8.5% over the forecast period, whereas China is forecast to propel at a CAGR of 7.8%. DNA sequencing services are expected to increase in the region to meet the increasing medical demands of the population.

•Japan is forecast to account for a market share of 2.7%, comparatively lower than the other competitive markets. However, the market is expected to offer diverse growth opportunities to businesses.

•Based on solutions and services, the data analysis and sequencing services segment is forecast to account for 41.8% of the global market.

•Under the end-user category, the academic institutes and research centers segment is anticipated to record more than 37.7% over the forecast period.

Market Competition:

Illumina Inc., Thermo Fischer Scientific Inc., Oxford Nanopore Technologies Plc, Agilent Technologies, Inc., QIAGEN, Eurofins Scientific, F. Hoffmann-La Roche Ltd., Takara Bio Inc., GENEWIZ, Inc., Hamilton Company, Macrogen Inc., Zymo Research Corporation, and Tecan Trading AG are a few of the major players in the global DNA sequencing services market.

Owing to the involvement of multiple prominent players, the industry exhibits intense competition. International firms like Oxford Nanopore Technologies plc, Thermo Fischer Scientific Inc., and Illumina Inc. In addition to making up a sizeable portion of the market, a number of regional players are active in important growing areas, mainly in North America.

Recent Developments

In December 2020, Eurofins Genomics released SARS-CoV-2 NGS services that are both cost-effective and optimized, allowing for entire viral genome sequencing.

In May 2020, Roche introduced the KAPA Target Enrichmentportfolio and the KAPA HyperExome whole-exome research panel for target enrichment during sequencing.

Illumina recently received Emergency Use Authorization (EUA) from the FDA for its COVIDSeq Test, which is used to sequence the entire genome of the novel SARS-CoV-2 virus.

Face2Gene LABS was launched in June 2019 by PerkinElmer, Inc. and FDNA, an artificial intelligence company, to provide genomic services in conjunction with Next-Generation Phenotyping (NGP) technologies for more accurate and efficient diagnoses.

Key Segments Profiled in The DNA Sequencing Services Industry Survey:

By Product Type:

Maxam–Gilbert DNA Sequencing

Chain-Termination Methods

Dye-Terminator Sequencing

Automation and Sample Preparation

Large-scale DNA Sequencing

New DNA Sequencing Methods

High Throughput DNA Sequencing

Parallel Signature Sequencing (MPSS)

Polony Sequencing

Pyrosequencing

Illumina (Solexa) Sequencing

SOLiD Sequencing

Others

By End Use:

Automotive Industry

Chemical Industry

Agriculture

Oil and Gas

Research and Development

Other End Uses

By Application:

Hospitals

Diagnostic Centers

Biotechnology and Pharmaceutical Industry

Academic Research Institutes

Other Application Areas

By Region:

North America

Latin America

Europe

Asia Pacific

The Middle East & Africa

[shadowtechteller]

Unraveling the Essence of Us: My Deep Dive into the Human Genome

Buckle up, my friends, because I am about to take you on an astonishing expedition into the very blueprint of life itself – the human genome! If you're picturing a mysterious, spiraling ladder that seems to hold the secrets of our existence, well, you're not far off. Let's talk about this incredible journey of discovery, what the genome actually is, and the mind-blowing future that’s unfolding before our very eyes, including precision medicine and groundbreaking therapies.

From Mendel to Molecules: The Historical Pathway

Imagine my surprise when I learned that the road to deciphering the human genome started in a serene garden with a monk named Gregor Mendel and his pea plants. Who would've thought that peas could teach us about inheritance? Fast forward through microscopes and molecular models, past the iconic double helix discovery by Watson and Crick, and we arrive at the Human Genome Project. A Herculean effort that began in 1990 to map all the genes in the human genome and, oh boy, the stories those genes could tell!

What's a Genome, Anyway?

So, what is this genome thing? Simply put, it's the complete set of instructions for making you, you. Packed within those cells in our bodies, which – fun fact – if laid end to end, could stretch to the moon and back multiple times! Each human cell houses this cookbook written in a code of just four letters: A, T, C, and G – shorthand for the chemicals adenine, thymine, cytosine, and guanine.

I like to compare the genome to the most comprehensive cookbook yet, with 'recipes' that are genes responsible for everything from your eye color to how your body responds to medication. Imagine billions of these letters in sequences, folded and tucked away neatly into 23 pairs of chromosomes – that's some efficient packing!

Precision Medicine: The Future Knocking at Our Cells

And then there's precision medicine – talk about a game-changer! Before diving into this topic, I thought one-size-fits-all medicine was the only way. But boy, was I wrong! Precision medicine is the art (backed by solid science) of customizing health care, with decisions and treatments tailored to individual patients. It's like having a suit perfectly tailored to your measurements, but for your health.

Thanks to our understanding of the human genome, doctors no longer glance at a textbook to guess what might work; they're crafting therapies based on the genetic nuances of each person. Think of it as a GPS for health, where the journey toward wellness is mapped out with individual genetic landmarks.

I heard an anecdote about a woman with a rare form of lung cancer. She wasn't responding to conventional treatments, and things looked grim. But then, scientists sequenced her genome and found a targetable genetic mutation. They tailored a therapy just for her genetic makeup, and it was a turning point. She went from preparing for the end to planning her future. That's the power of precision medicine – it can turn the table on terminal diagnoses.

The Present and Beyond: Therapies and Possibilities

Right now, we're standing on the edge of a new frontier where gene editing tools like CRISPR are the scalpels. These molecular scissors can snip and edit the genes that contribute to inherited diseases. Imagine a world where conditions like cystic fibrosis or sickle cell anemia could be corrected before a baby is even born.

This isn't just future-speak; it's actually happening. The first trials of gene therapies are giving hope to people with conditions that were once thought untreatable. We’re talking about a new era where ‘genetic surgery’ could become as routine as getting your tonsils out.

And the possibilities? They're as vast as the genome itself. We're looking at the potential to prolong human life, to augment our bodies to better resist diseases or perhaps adapt to new environments – even space. We might be able to reprogram our biology to avoid aging the way we know it. It sounds like science fiction, but then again, decoding the human genome once did too.

Wrapping Up the DNA Double Helix

As I wrap up this genetic tapestry, I can't help but be in awe of how understanding our genome has become central to our lives. This knowledge shapes not just our health care but also our identities and our futures.

The genome is not just a story of life; it’s the autobiography of humanity, written in a language we're just beginning to fluently read. Each new discovery is a page turned, a chapter unfolded, a deeper understanding of the profound narrative we all share.

So, what's next on this genomic journey? I'll tell you this much: the future is bright, and it's personalized. With our genomic roadmap in hand, we're steering toward a horizon where medicine is tailored, treatments are precise , and the once incurable becomes curable. Hold onto your seats, because this is just the beginning, and I, for one, can’t wait to witness where we go from here—with every snippet of DNA, we're not just unlocking the secrets to our health, but also the untapped potential of humankind. The genome’s journey is far from over, and the next chapters promise to be nothing short of revolutionary!

[dropsofsciences]

Growing data in plants

A collaboration between science and art is showing the way to cleaner data storage. That is achieved with using the DNA of plants to store data into. Everyday when we search for our data on the internet cloud we are performing a query in volumous data centers, buildings around the world full with wires and cooling systems that run heavily on electricity and produce CO2. The global consumption of these centers reaches the energy demand of the whole UK, while until 2030 this is projected to rise by 20%. This everincreasing consumption of energy is linked to the concept of data warming, where large volumes of data become responsible for part of the global warming of the planet. The "grow your own cloud" project explores an alternative future where data are stored in an organic environment that the community of citizens can cater to. Imagine a data center that does not run on electricity but only on water and CO2. With the help of biotechnologists at the University of Washington, data such as text, jpeg images and mp3 music files are sequenced not into bits of 0 and 1 as in classic digital data encoding, but into the alphabet of dna, the nucleobases Adenine, Thymine, Cytosine and Guanine. The data are then stored in the idle part of the DNA of plants. Since not all natural DNA sequencing corresponds to useful genes for the evolution of the plant, the DNA molecule chain provides a vast amount of free space to encode on by artificially rearranging nucleobases in it. In order to retrieve the information, one takes a liquid sample of plant DNA and inserts it into modern DNA decoding devices, that decipher the stored information and either project it onto screens or play it into speakers. This way the data storage becomes a local islet of O2 producing plants that combat global warming while the data format does not ever become obsolete, in contrast to the digital data storage.

The project won the prize in Falling Walls Berlin 2022 in the category science meets art.

sources: growyourown.cloud https://cyrus.website/data-garden/ Falling Walls Berlin, 7-9 November 2022

image credit: Grow Your own Cloud

[magpie-art-reblogs]

It's a bond to last a lifetime

Love is encoded in our dna

Ok that's enough puns for now. From one science nerd to (maybe) another, happy Valentine's day!

[tomtenadia]

Be my Cytosine

Rowaelin month day 12 - delayed love confession

Ok, today’s title is a weird one. If you have a knowledge of basic biology you will know that DNA has four nucleobases called Adenine (A), Guanine (G), Cytosine (C) and Thymine (T). You should also know that C always pairs with G and A pairs with T but in RNA A cheats on T with Uracil. This should help to understand the confession at the end. In the fic Rowan is a geneticist... ( a field your truly finds extremely fascinating).

Apologies for the biology lesson. I felt I had to give an explanation for the weirdness of the title which is, by the way, also a play on the phrase Be my valentine...

Anyway... enjoy it!

Aelin was at the pub waiting for Rowan. He had texted her to meet him at their pub. She had a tiring day at work and was more than happy to finish off the day at the pub with her best friend.

Aelin was a high school teacher and Rowan was a scientist. He worked in a lab as a geneticist.

They had friends in common, and they met through them but their beginnings had been turbulent. The man had confessed he hated her guts and she had admitted she was not his fan either. The animosity had lasted for about a year. Then something shifted and slowly their relationship settled and they became friends. Until the she broke up with Chaol, he kicked her out of the flat and Rowan had been the first one to offer her his spare bedroom. So they became flatmates and the friendship blossomed even further to the point she could now call him her best friend.

What she had never had the guts to tell him was that she had been in love with him for a while now. But she had kept it to herself. They lived together and it might complicate everything between them. So she had pined in silence. Not even her friends knew about her secret.

*

Rowan was looking forward to meet Aelin at the pub. He had big news and she was the first person he wanted to share it with.

The job offer had been the culmination of years spent on books, his PhD years spent in labs day in and day out and then his currently living in a lab. but all of the sacrifices had finally paid off. He had been offered the position as a lead scientist in Doranelle as a part of the research team at the country’s most prestigious hospital. It was the opportunity of a lifetime.

He had spent the day in a daze.

Now he was driving and he hoped she would be happy for him.

Once at the pub he parked and finally walked in. He scanned the venue and finally spotted her blonde hair. She was sitting at a table with two pints in front of her.

“I got your favourite as soon as you told me you were five minutes out. Still nice and cold.

They clinked their glasses and Aelin took a huge gulp of her beer.

“Long day at work?” He mused at the avidity with which she drank the first gulp.

“Teenagers and their drama…” she explained “and on top of that, parents who think they can tell you how to do the job that you have been doing for the past ten years.”

“Just tell them to fuck off.”

“Says the man who works all day with petri dishes and DNA. They at least don’t talk back to you.”

Rowan chuckled “DNA mutating might be its way to tell me to fuck off.”

Aelin snorted so hard at the joke, while she was taking a sip that she had inhaled a bit of the beer and was now coughing after the drink went down the wrong pipe.

Rowan patted her back and she coughed a bit more.

“Are you okay?”

Aelin nodded “sorry I just imagined a DNA strand unfolding and in cartoon style morph back into a middle finger in the microscope.”

This time was the turn of Rowan to laugh. She loved that dynamic of theirs. She had even brushed up on some of her high school biology to make jokes. Once for Samhain she had dressed up as a Punnett square. Rowan had laughed for then minutes, then went and corrected it, saying that the combinations were incorrect.

Rowan cleared his voice and the atmosphere shifted all of a sudden “I got a big news today.”

Aelin grinned “Spill you heterozygote beans, Whitethorn.”

“I got a job offer.” He admitted, taking a sip of his beer “An hospital in Doranelle has offered me a lead scientist position for their project on genetic mutations. They read all my papers on a specific disease and its onset. Now they want me to work in one of their state of the art labs.”

Aelin gasped. That was an incredible opportunity. She knew how hard he had worked to get where he was and the job offer was the reward for all the time he had sacrificed and personal life as well. He and Lyria had dated for a couple of years until she left him because he was more dedicated to her job than her.

And if a part of Aelin was elated for him, the other, the selfish one, was hurting. He would leave. He would have a brand new successful life in Doranelle. Away from her. It hurt.

“Ro, that is absolutely amazing,” she hugged him hard and tried to hide the ache in her heart. 

“I will need to leave in two weeks. I can move the lease of the flat to your name, I— ”

Aelin shushed him “let’s just celebrate tonight.” He nodded and toasted to a new adventure.

*

Two weeks later

Aelin had begged Rowan to let her drive him to the airport. He had tried to convince her that he was happy to take a taxi, but Aelin had been stubborn and now she was helping him unload his luggage from the trunk of her car.

Her heart was racing. The previous night she had cried herself to sleep. The idea of him leaving her for good was killing her.

She accompanied him to check-in and forced herself to calm the tears that were now threatening to spill.

And when he started walking to the security area, the place where she knew she’d have to eventually say good bye to him, she froze.

Rowan noticed she had stopped “What’s wrong, fireheart?”

Aelin looked up at him, tears finally broke free “I love you.” She sobbed. “Rowan Whitethorn, I love you. You are the C to my G.” She let out a wet chuckle “not A since it cheats on T with U.”

Rowan laughed.

“What I am trying to say is that is you. Only you. And I know it’s the wrong time because you are going away to your dream job, but I had to tell you.” She was now sobbing and Rowan pulled her to his chest “you are the most amazing woman I ever met and I don’t deserve you.” He pulled back but kissed her on the forehead “be happy, Aelin.”

And he slowly walked away from her. Aelin watched at him disappear through the barriers. Never looking back. Aelin cried and cried. She stared at the screen watching the message switching from Boarding Now to Gate closed. She sat on a chair in the waiting are and let her desperation take over.

*

It was half an hour later when she heard a voice call her name. She hadn’t moved from her chair, she just could not leave.

It couldn’t be. He was on a plane.

She stood and turned and saw Rowan standing near the chair with his duffel bag on his shoulder.

“Rowan?” She breathed, her voice shaken by sobs “the plane.”

“I got off the plane.” He chuckled “and pissed off a lot of people since now they have to unload my luggage.”

“You got off the plane.”

He nodded again and took a step to her “I sat at my seat and all I could think was your confession. And realised that I have been an idiot.” He took her hand “I love you, Aelin. You are as well the C to my G. It took me almost to take off to realise it but better late than never.”

Aelin threw herself in his arms and he held her tight “and where else will I find a woman who uses genetics for a love declaration? That was super hot.” Aelin chuckled while inhaling the scent of pine and snow that was so typically him “what about your job?”

Rowan shrugged “my boss was quite gutted at losing me. I guess they will be happy when I phone tomorrow and tell them that I am happy to go back if they still want me.”

“But—” Rowan shushed her with a kiss.

“No buts, I have no regrets. This is the right choice.” And he kissed her.

A few minutes later a voice called him “Mr Whitethorn.” He turned and saw an airport attendant carrying his luggage.

“Thank you, and I am sorry.”

The man grunted something and walked away.

Aelin grabbed one of the bags and his hand and they walked out.

“Let’s be clear, I blame oxytocin.”

Rowan stopped and pulled her to him and then lifted Aelin in his arms, not caring about all the hundreds of people around them.

“I love you, Aelin Galathynius.”

[meltwonu]

46. “Were you just masturbating?”

         “U-uh..no, i was just..”

         “Want some help?”

72. “You don’t need to cover up the bruises/hickeys.”

notes; fingering, marking, some science jargon, ive always been an arts student so😗, also idk if yall can tell but i love writing playful fucking/sex for jun bc i think he’s just??? So playful and cute??? Which i LOVE kdjfhsdk 😭😭,  this is only slightly long but for space sake the rest is under the cut! Thank you for requesting! Enjoy! 💕

Jun as your tutor is a toss up.

Some days he actually helps you understand the material.

And most days he decides eating you out for 45 minutes is enough ‘learning material’.

Last time, he made you cockwarm him while he ‘helped’ you study for your molecular biology exam; the same exam which you had failed miserably.

This time, however, you decide to beat Jun to it; fingers traveling down your own torso and straight into your panties. You figure if you got off before he showed up, then there’s no way he’d be distracted during your tutoring session if you weren’t in the mood to fool around either.

A stuttered moan spills from your lips, eyes fluttering shut when your fingertips graze against your already wet folds. Your legs part even farther as your imagination wanders; thoughts of Jun’s hands on your skin and his saccharine moans next to your ear as he fucks you.

“Hey! Whoa---shit!”

In the blink of an eye, your legs snap shut and you pull your fingers out of your panties, sitting up in bed with a blush on your face as you stare back at Jun. “What the fuck, Jun!? How did--How did you even get into my apartment!?” He immediately ignores your question, stepping into your room and locking the door behind him.

“Were you just masturbating?”

“U-uh… No, I was just…”

“Want some help?” He doesn’t wait for a reply, instead grabbing a book from his things before he settles on the bed in front of you. “Spread your legs.”

“What? W-wait, you’re supposed to help me study! I failed my exam because of you, y’know!” You pout at Jun, arms crossed as he rolls his eyes.

“Exactly, which is why I showed up early. So I could help you actually study. I didn’t think you were gonna be in here getting off in the meantime.” He pauses, flipping the book open before tossing it to your side. “Your roommate let me in by the way, and I heard your professor is letting you retake the exam.”

You nod, biting the inside of your cheek. “I basically cried in front of her. She felt bad so she said I could retake it on Friday. But I really need to study, Jun…”

He nods in reply, eyes glancing towards the textbook. “And we will! But since I’m here early…” Jun places his hands on your knees, prying your legs apart. You can feel the arousal pooling in your body when your eyes meet his; legs spreading to accommodate him between them. “Let’s see how much info you actually retained from last time.”

You can only stare at the ceiling, mind completely blank when Jun finally sinks his fingers into your pussy after torturous minutes of teasing. “O-oh fuh--fuck--”

“I asked you a question.” He comments in mock annoyance, fingers unmoving as you clench around his digits. “W--what was the question again?” You ask breathily, leaning up on your elbows as Jun stares down at you.

“What are the purine bases in DNA?” You can only let out a choked sob, squirming when Jun doesn’t make an effort to move. “I--fuck, I don’t remember… Um, c-cytosine a-and thymine?”

“Nope, those are pyrimidines. C’mon, this is an easy question.” Jun leans down, lips pressed against the column of your neck. He leaves soft kisses, lips ghosting against the shell of your ear. “Don’t you wanna cum?” He whispers; his sweet voice sending thrums of arousal down your spine.

“A-ah, u--um, adenine and--and g-guanine?”

Jun smiles against your skin before he sucks a lovebite onto it, fingers inside your pussy finally moving as he starts thrusting them into you. “Mmh, J-Jun…” Whining, you tangle your fingers in his shirt, eyes fluttering shut at the combination of his lips and fingers making you feel good.

He leaves a few more lovebites on the column of your neck before he start to pull away. “No, no, no, don’t s-stop, please!” You beg; your grip on his shirt only tightening. He licks his lips, eyeing the blossoming marks on your neck. “Answer one more question and then I’ll let you cum. But then we’re really studying afterwards, okay? Can’t have you failing again.” You nod frantically, a sigh of relief on your lips when Jun doesn’t stop thrusting his fingers. He scissors them inside of you; curling them to graze against your g-spot.

“Hm… Give me… the three stages of DNA isolation. But in order.”

fuck.

Jun slows his pace when you take too long to answer, a small ‘tsk’ falling from his lips. “Guess you don’t wanna cum?” You can only whine; squirming when you feel him slowly easing his fingers out of you.

“No--no I wanna c-cum! Please…” He pauses his movements, waiting on you to answer.

“It’s---It’s… l-lysis, precipitation, and, ah, and p-purification? Right?”

“See, I knew you remembered some stuff.” 

Jun slides his fingers in knuckle deep, smirking as he places his thumb on your clit. He doesn’t say another word as he leans in again, lips at the junction of your neck before he sucks on the skin; soft nibbles making you jolt.

You try to keep quiet knowing the two of you aren’t alone, but Jun’s pace quickens, fingers curling inside of your tight walls when he feels you close to cumming. “Jun--Jun---I’m--I--”

“S’okay, you can cum.” He mumbles against your skin, leaving another blossoming mark on your skin just as you orgasm crests; chest arching up into his as you bite your lip to keep in your noises. Your walls throb around his fingers, a soft groan of his own spilling from your lips when he imagines it’s his cock inside of you instead.

Jun keeps pumping his fingers, thumb on your clit still rubbing circles until he feels you starting to come down from your high. You whimper his name, quietly begging him to stop when the overstimulation starts to bite.

He slowly eases his fingers out, bringing them to his lips as he licks them clean.

“My neck is all… wet…” You mutter, fingertips ghosting across the tender lovebites Jun’s left on your neck. He grins at you from around his fingers, popping the digits out before he leans in again.

“I know you like it when I’m messy. And anyway, you don’t need to cover up the hickeys, y’know. I left them there for a reason.”

You can only quirk a brow at him, waiting for him to continue. “What? D’you think I was just fuckin’ you for fun? I know I’m not exactly the most straightforward guy and I think we might’ve fucked it up a bit but do you wanna go on a date with me after your retake?”

An awkward laugh spills from your lips; cheeks blooming into a pink when you realize he’s being serious.

“I--yeah, um, sure? I’d like that…” You trail off, suddenly shy.

“Okay, well, let’s get to studying then! If you ace your retake, I’ll fuck you however you like too. Deal?”

You grin up at the male, already having a few ideas lined up. “Sure, it’s a deal.”

[wisdomrays]

TAFAKKUR: Part 207

Functional Art in the Nucleus: DNA

Volumes of books and hundreds of articles have been published about the structure and functions of DNA, since the day two renowned scientists from Cold Spring Harbor laboratories, who would later win the Nobel Prize, described the double helix structure of it. Perhaps one common element that shines through all the publications is their emphasis on the numerous specific functions of DNA, if not the fascinating harmony of these specific functions in a living organism. In this article, we will take a look at a few small droplets from the vast ocean of information about the multi-layered functions of DNA that are orchestrated in an awe-inspiring manner.

The cell is the structural, functional, and biological unit of all organisms. All information needed for numerous processes in a cell, including repair and division, is contained in DNA (Deoxyribonucleic acid). DNA is a huge single molecule with intriguing features. How can a single molecule have such a dominant role in preserving information essential for the continuation of life? What are the mechanisms and levels of organization during its function? What does DNA mean for a single cell or for a human being? It’s impossible to answer these great questions in a single article; however, understanding the ways DNA exerts its role, DNA’s impact on multiple levels ranging from a single cell to an organism, and coordination between various levels, can potentially open up new frontiers in our mind and in our perception of life.

“Double helix” architecture of DNA DNA has an elegant structure that forms the basis for all of its functions. DNA is a repeating structure of nucleotides. Each nucleotide is formed of a phosphate group, 5-carbon sugar (deoxyribose) and a nitrogen-containing base attached to the sugar from outside to inside (See Figure 1a for a schematic view of DNA). There are four types of nucleotides in DNA, differing only in bases. We can consider bases as the identity of nucleotides. These four nucleotides are shown with letters A (adenine), T (thymine), G (guanine) and C (cytosine). Thousands of nucleotides bound with sugar-phosphate covalent bonds come together to form long strings. The sugar-phosphate backbone can be imagined as the steelwork of a skyscraper. The nice thing about nucleotides is their specific match to each other in double helix. A forms a base pair with only T, and G forms a base pair with only C. These pairs are bound to each other with hydrogen bonds. This feature is the key that makes DNA a double ladder. Two strings of nucleotides form a double helix by selective interactions of As with Ts, and Gs with Cs (See Figure 1b for 3-D structure of DNA). In DNA structure, hydrophobic bases tend to stay inside of double helix and hydrophilic sugar-phosphates stay outside interacting with water in nucleus. This feature helps DNA to form a double ladder. The length of the sugar-phosphate backbone is more than the bases. To compensate for the length difference, the sugar-phosphate backbone wraps around the bases inside, as a road wraps around a mountain to climb to the top. This simple difference is the main reason for DNA to form a helix.

The double-stranded nature of DNA with specific base pairing is one of its key features as genetic material. DNA is replicated using one strand as a template. Replication machinery reads one strand of DNA and builds the second strand by putting As against Ts and Gs against Cs. If a mutation occurs in one strand, it can be repaired using the second strand. This system is like photocopying DNA from itself instead of building it from scratch every time. That is why specific base pairing of nucleotides in the double helix makes it possible to replicate DNA through generations, protecting its integrity and information content. The code of DNA, an alphabet with four letters DNA contains the information to produce nano-sized cellular machineries called proteins. We mentioned that there are four types of nucleotides. Nucleotides are like letters in DNA, three of them are code for one amino acid of protein. We can make it more understandable by giving an example: “ATG-GCC-CTG-TGG-ATG” as a nucleotide sequence of DNA corresponds to the first five amino acids of a protein called insulin (a hormone regulating blood glucose level that is important in diabetes) and amino acid sequence is methionine-alanine-leucine-tryptophan-methionine. The code is so sensitive that even a single mistake in the sequence of DNA can cause serious diseases in humans such as sickle-cell disease or cystic fibrosis. With all these nucleotides, DNA can be thought of as a book containing amino acid sequence information for thousands of proteins (about 30,000 in humans). The amount of information contained in DNA is incredible: a typical human cell contains 2 meters of DNA that is tightly packed by proteins in the nucleus. If we tried to write the information from DNA into books, the book would contain over one billion words and 1,500,000 pages. DNA-protein interdependency and the cell as a micro-factory DNA can be thought of as an instruction manual that stores information for proteins and RNAs. Proteins, as molecular machines, perform particular tasks such as energy production and synthesis of DNA and RNA (See Figure 2 for the structure of proteins). Certain proteins read the information on DNA and make a transient copy of certain regions of DNA. These copies are called messenger-RNAs (mRNAs) and mRNAs are transported from nucleus to cytoplasm (See Figure 3 for representation of mRNA production from DNA by proteins). In cytoplasm, the information on mRNAs is read by protein complexes called ribosome. Ribosomes produce new proteins processing the data from mRNAs.

This information flow from DNA to proteins is called central dogma in molecular biology (Figure 4). The data that is encoded in DNA can be read, translated, and put into the form of product only by proteins. We can conclude that for a protein to be produced, DNA is essential; for DNA regions to be read into proteins, proteins are essential. So, there is interdependency between proteins and DNA. Proteins without DNA have no future and no ability to regenerate and DNA without proteins is just like an instruction and manufacture manual of a computer without the user and computer itself. We can imagine the cell as a sophisticated factory, and proteins as the machines of the factory. DNA includes the instructions for the factory to be rebuilt and for itself to be rewritten for every new factory. It has instructions on how to build every machine in the factory. It has also codes for when and how much of these machines should be produced (we will discuss more about these codes on DNA in the next section). On the other hand, the timing and control of all these productions also depend on machines in the factory. Some of these machineries read and decode the instruction manual, some of them produce new machines by reading the decoded copies of the instruction manual, some of them act as sensors for the signals, some of them transmit signals to other machines, some of them produce signals by measuring the levels of materials in the factory, some of them function in communication with other factories, and so on. As we can see, DNA and proteins are meaningful for life only when they are together in the excellent cell context. This is a perfect example of the principle that the whole is bigger than the sum of its parts, because each element of the cell system has limited potential, until it comes together with the others to blossom into life.

The famous term “Gene” We can think of genes as functional units of DNA. A gene has the information content for at least one protein. Humans have about 20,500 genes that are read by protein machineries to produce proteins. Special proteins read the information on genes and make a transient copy of these certain regions of DNA. The process of making a copy of a gene as an mRNA is called transcription.

Genes don’t only store information; they have an intrinsic architecture of design to coordinate transcription utilizing three main components: promoter, coding region, and terminator. The promoter is the gene region that signals for the start of transcription. Protein machineries bind to the promoter and activate transcription. The coding region has the information for the amino acid sequence of the protein. The terminator region gives the stop signal for transcription. There are different functional regions on DNA located between separate genes such as enhancer regions that are platforms for binding regulatory proteins to tune the transcription.

The coding region of genes has multiple reading blocks for amino acid sequences and these reading blocks are called as exons. For some genes, different combinations of exons can be put together to give rise to different proteins. This mechanism allows one gene to be able to produce multiple proteins, increasing the efficiency of genetic material. A similar mechanism is used to produce antibodies (proteins recognizing foreign antigens) by the immune system. Different regional genes come together by a mechanism of DNA rearrangement (V(D)J recombination) and their differential combinations form many different antibodies. For example, a part of the antibody that is called a heavy chain is produced by a DNA region containing 65 variable (V) genes plus 27 diversity (D) genes and 6 joining (J) genes (5, 6). This produces a combination of 65 V genes x 27 D genes x 6 J genes = 10,530 heavy chains. There is a similar mechanism of rearrangement for light chain and variable region of antibodies, which result in millions of different antibodies for host antigens. A single example in the immune system shows us that DNA not only has a decent design for the coding system, but it also has ingenious and creative mechanisms to maximize its potential.

Gene expression is orchestrated during development and formation of organs The human body which consists of more than 1013 (ten trillion) cells is generated from a single cell called the zygote (see Figure 5). This tells us that, in a single cell, all the information and instructions to build and coordinate the systems of human body is encoded. Different tissues and organs including muscles, nerve cells, connective tissue, and eyes are fruits of one single cell. They all contain the same genetic information. Then what makes them different?

Promoters, enhancers, and repressors located in and nearby genes are important in spatial and temporal control of gene expression in different cell types of the body. Each cell type in our organs expresses a different subset of genes; this is what gives a cell its identity. For example, in muscles, myosin is expressed and in the eye’s retina, rhodopsin is expressed. Myosin functions in contraction and rhodopsin functions in vision. What determines the expression of rhodopsin in the eye but not in a muscle? The determination process occurs during development by programmed interactions of specific proteins called transcription factors, and restricted regions of DNA including promoters and enhancers. During development, certain regulatory proteins in a specific cell type, bind to DNA regions of only some genes (for example, in future retinal cells of the eye, rhodopsin gene would be activated but not myosin) and this predetermination orchestrates differential expression of genes to give rise to hundreds of different types of cells.

Different layers of complexity and organization related to DNA

There are different layers of function for DNA—each subtitle of this article tries to focus on a certain layer of function. DNA as a molecule has a double helix structure and is replicated through generations to preserve genetic information. It stores genetic information and has a four-letter alphabet for the expression of proteins. In the second layer, DNA has an informational unit called gene and thousands of genes are encoded in DNA to contain information for proteins. Each gene is controlled individually by making use of promoters and enhancers. In the third layer, all processes in the cell micro-factory as an entity are performed through interactions of DNA and proteins with each other and among themselves. Proteins read DNA code and work as cellular nano-machineries. In another layer, temporal and spatial expression of genes on DNA are orchestrated and different subsets of genes give rise to different cell types and organs. Organs communicate with each other to function properly and keep the balance and homeostasis of the body. The information stored in DNA not only coordinates highly sophisticated processes of a single cell, it simultaneously projects the whole body system of a human being, which is billions times bigger than a single cell.

DNA functions in all these different layers and keeps a great harmony in coordination between various layers of function. After grasping this complexity, organization and communication from a single molecule, to proteins, to a single cell, to tissues and organs, and to a human being by utilization of DNA, should not we ask ourselves, “can these elements come into existence by random forces and collisions?

[tinycartridge]

Thymine’s [SELECT START: Harmony] haunts us with Game Boy ghosts, slimes, and devil girls ⊟ 

LA micro-gallery Capsule Corner is hosting another collection by Thymine with 30 custom cartridges (new designs plus reprints from last year’s show) and two painted Game Boys featuring her original artwork. A lot of her artwork for this round are ghosts and slimes, two of my favorite things!

From Thymine’s artist statement:

“I think my art is overall usually seen as cute, but it touches upon darker, bittersweet themes sometimes. Some of the carts are bright and silly, some sad or scary, and some that are inbetween. With this show I wanted to have fun with the carts and this idea. I also wanted to have it as a reminder that with the bad comes the good (and vice versa), & that the darkness and light need a balance of eachother and work in harmony.“

Most of them are sold already, but you can still buy a handful of Thymine’s framed Game Boy carts for $50 apiece -- otherwise you can see them all online at Capsule Corner’s site or in person at The Hive Gallery and Studios. The [SELECT START: Harmony] exhibit will run there until July 10.

JOIN CLUB TINY AND OUR DISCORD Support Tiny Cartridge!

[ink-covered-hands]

shrug

[thyminet]

🎉Happy New Year everyone!🥳

🎍あけおめ🌠今年もよろしくお願いします🙏

First art of the year is my annual Monster Hunter New Year illustration! This year is the year of Lagombi! 🐇

Hoping this year will be good to everyone!

[bsbludwig]

Our latest paper, just out in Nature Biotechnology: my group worked with chemist Chunxiao Song and his team to develop a novel way to sequence epigenetic DNA modifications. Our technique is less damaging to DNA than the current state of the art, and converts modified cytosine directory to thymine, instead of the inverse. This makes sequencing for epigenetic marks cheaper and faster, and will facilitate applying epigenomics to single cells and cell-free DNA. Very proud of Gergana Velikova for developing "asTair", the computational analysis pipeline (available now on bitbucket).

[kh15963]

View this post on Instagram

A post shared by Hector | Creative Clarity Coach | Songwriter 🧙🏽 (@hector.the.alchemist)

🎵🔊TURN YOUR SOUND ON!!!🔊🎵 💜FULL VIDEO ON IGTV💜 °Euphoria° - DOG DAYS ARE OVER · Euphoria / divinity Takes over me / exhale, relieve And now I see / And I feel free Chromaticity / Deep clarity My soul feels / Look through me Soigné / Darling Body glowing/vibrates softly Euphoria Is all I need This moment here: All that exists. Introspirit fluorescence Norepinephrine Naïveté To dopamine I pray Do you feel it, Body transmits Placid fruition Lucid intuition Conscious unconsciousness, oh Oh I feel it Aura turns ambience: Red, blue, green, ianthine Adanine to thymine (purine) Cytosine to guanine (pyrimidine) Euphoria. · Track Influences: AURORA @björk (Utopia) @runcrywolf (Cataclasm) Rosalía and her simple yet complex chord/melodic/lyrical beauty Kingdom Hearts (Simple and Clean, Sanctuary: After the Battle) · I got new things coming for ya this year! I recently got a new free DAW to produce music professionally called LMMS! It's so amazing 😭 I've been getting back into my flow! New music, poems, and aesthetics! This is the draft of a song I'm working that literally has made me cry. I'm so proud of how I was able to structure the chords and melodies to evoke the exact feelings I was looking to convey. These past few years have helped me grow so much artistically. Can't wait to share even more with y'all this year. 💛 · 🏮☀🎵"STRANGE ECSTASY" EP COMING SOON🎵☀🏮 · YOUTUBE CHANNEL: /TheSchwaWasntHere (LINK IN BIO!) SNAP👻:dogdaysaohector FB 🎵 PAGE: @ dogdaysareoverhc BandLab: dogdaysareover_hc · Art is the soul's exhale. · Outdoor gear discounts: @maderaoutdoordiscounts_hectorc · · · · · #musician #music #classical #poetry #artist #producer #singer #producer #wow #love #musicproducer #newmusic #beats #art #latino #song #studio #instagood #songwriter #folk #gay #bjork #aesthetic #photography #kingdomhearts #dazed #musicvideo #musicians #guitar #videogamemusic https://www.instagram.com/p/BsHNE0AlyOP/?utm_source=ig_tumblr_share&igshid=1ofg1a2446wfh

[leyhejuhyunghan]

Musée d'Orsay Aristide Maillol. The Quest for Harmony, chenu, Qui a la cime blanchie (par la neige ou l’écume par exemple), Aristide Maillol : classique ou moderne ?, Aristide Joseph Bonaventure Maillol (French, 1861–1944) École des Beaux-Arts he studied there under Jean-Léon Gérôme and Alexandre Cabanel., Sotheby’s "Self Reflected" —a giant, dynamic 23k gold microetching depicting neural activity in the human brain Dr. Greg Dunn in collaboration with Dr. Brian Edwards, Bayer What is gene editing? A (adenosine), C (cytosine), G (guanine), and T (thymine) CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats), Touch Of Heaven - Hillsong Worship - King of Kings (Live)

Musée d'Orsay Aristide Maillol. The Quest for Harmony, chenu, Qui a la cime blanchie (par la neige ou l’écume par exemple), Aristide Maillol : classique ou moderne ?, Aristide Joseph Bonaventure Maillol (French, 1861–1944) École des Beaux-Arts he studied there under Jean-Léon Gérôme and Alexandre Cabanel., Sotheby’s "Self Reflected" —a giant, dynamic 23k gold microetching depicting neural activity in the human brain Dr. Greg Dunn in collaboration with Dr. Brian Edwards, Bayer What is gene editing? A (adenosine), C (cytosine), G (guanine), and T (thymine) CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats), Touch Of Heaven - Hillsong Worship - King of Kings (Live)

https://blog.naver.com/artnouveau19/222822588842 https://www.facebook.com/watch?v=1025754421413560

https://en.wikipedia.org/wiki/Aristide_Maillol https://www.sothebys.com/en/buy/auction/2022/self-reflected/self-reflected-a-giant-dynamic-22k-gold?locale=en https://www.bayer.com/en/news-stories/what-is-gene-editing?fbclid=IwAR0DuWDULVNUoHAukHW_1Jdx5IKLdpOjyLZAx_m2rrPo1xJ2zh42tAdsWRE https://youtu.be/htz6HN2DMgM

https://youtu.be/nxxr47zEUxE

https://youtu.be/dQl4izxPeNU

Musée d'Orsay 

Quel rapport entre cette femme nue sculptée par Maillol et le révolutionnaire français Auguste Blanqui ?

Réponse dans ce premier épisode d'une série de vidéos réalisées à l'occasion de l'exposition "Aristide Maillol. La quête de l'harmonie" présentée jusqu'au 21 août au musée d'Orsay.

Regardez la série complète (sous-titres français).

➤bit.ly/3PgxMhX

.

What is the connection between this naked woman sculpted by Maillol and the French revolutionary Auguste Blanqui?

Answer in this first episode of a series of videos made for the exhibition "Aristide Maillol. The quest for harmony" presented until August 21 at the Musée d'Orsay.

Watch the full series.

➤bit.ly/3odVrDX

https://www.facebook.com/watch?v=1025754421413560 Aristide Maillol. The Quest for Harmony

5 videos 7 views Last updated on Jul 11, 2022 https://www.youtube.com/playlist?list=PLwUa6C-N-kpa3-BptMwp7yPO7y9e3P-DN

These five videos provide an in-depth look at the subjects addressed by Stanislas Valroff in the documentary "Aristide Maillol, the quest for harmony", co-produced by Bel Air Media, the Musée d'Orsay and Museum TV, in connection with the exhibition devoted to the artist, presented at the Musée d'Orsay from April 12  to August 21, 2022.

chenu [ʃ(ə)ny]

형용사 [문어] 늙어서 백발이 된 

형용사 [문어] (나무가 오래되어) 윗부분에 잎이 없는 

남성형 명사 [속어] 최상의[최고급의] 것 

Qui a les cheveux blanchis par la vieillesse. 

(méton) S’applique à la barbe, aux sourcils, aux parties du corps et même aux objets en les personnifiant. 

(poétique) Qui a la cime blanchie (par la neige ou l’écume par exemple). 

[Adjective] hoary, snow-capped 

[Adjective] grey-haired, grey-headed 

[Adjective] elderly 

https://dict.naver.com/frkodict/#/search?query=chenu

Musée d'Orsay

@MuseeOrsay

·

Jul 9

Aristide Maillol : classique ou moderne ?

Sur 

@franceculture

 à l'occasion de l'exposition "Aristide #Maillol. La quête de l'harmonie" à Orsay, une passionnante interview d'Ophélie Ferlier-Bouat, l'une des commissaires de l'événement.

Par 

@MGarrigou

https://twitter.com/MuseeOrsay/status/1545482860269674496  

Aristide Maillol : classique ou moderne ?

Mardi 31 mai 2022

https://www.radiofrance.fr/franceculture/podcasts/sans-oser-le-demander/maillol-4453420 Deux jardiniers portent des maquettes de statues de Maillol au Louvre, le 14 janvier 1964 ©Getty - Keystone-France

Aristide Joseph Bonaventure Maillol (French, 1861–1944) Aristide Joseph Bonaventure Maillol (French: [mɑjɔl]; December 8, 1861 – September 27, 1944) was a French sculptor, painter, and printmaker. Maillol was born in Banyuls-sur-Mer, Roussillon. He decided at an early age to become a painter, and moved to Paris in 1881 to study art.[1] After several applications and several years of living in poverty, his enrollment in the École des Beaux-Arts was accepted in 1885, and he studied there under Jean-Léon Gérôme and Alexandre Cabanel.[2] His early paintings show the influence of his contemporaries Pierre Puvis de Chavannes and Paul Gauguin.

Gauguin encouraged his growing interest in decorative art, an interest that led Maillol to take up tapestry design. In 1893 Maillol opened a tapestry workshop in Banyuls, producing works whose high technical and aesthetic quality gained him recognition for renewing this art form in France. He began making small terracotta sculptures in 1895, and within a few years his concentration on sculpture led to the abandonment of his work in tapestry.

The subject of nearly all of Maillol's mature work is the female body, treated with a classical emphasis on stable forms. The figurative style of his large bronzes is perceived as an important precursor to the greater simplifications of Henry Moore, and his serene classicism set a standard for European (and American) figure sculpture until the end of World War II.

Josep Pla said of Maillol, "These archaic ideas, Greek, were the great novelty Maillol brought into the tendency of modern sculpture. What you need to love from the ancients is not the antiquity, it is the sense of permanent, renewed novelty, that is due to the nature and reason."[5]

His important public commissions include a 1912 commission for a monument to Cézanne, as well as numerous war memorials commissioned after World War I. Maillol served as a juror with Florence Meyer Blumenthal in awarding the Prix Blumenthal (1919–1954) a grant awarded to painters, sculptors, decorators, engravers, writers, and musicians.[6]

He made a series of woodcut illustrations for an edition of Vergil's Eclogues published by Harry Graf Kessler in 1926–27. He also illustrated Daphnis and Chloe by Longus (1937) and Chansons pour elle by Paul Verlaine (1939).[7] Nazi-looted art[edit]

During the German occupation of France, dozens of artworks by Maillol were seized by the Nazi looting organization known as the E.R.R. or Reichsleiter Rosenberg Taskforce. The Database of Art Objects at the Jeu de Paume lists thirty artworks by Maillol.[8] The German Lost Art Foundation database lists 33 entries for Maillol.[9] The German Historical Museum's database for artworks recovered by the Allies at the Munich Central Collecting Point has 13 items related to Maillol.[10] Maillol's sculpture ‘Head of Flora’ was found in the stash of Cornelius Gurlitt, son of Hitler's art dealer Hildebrand Gurlitt[11] together with lithographs,[12] drawings and paintings.[13]

A photograph from May 24, 1946 shows "Six men, members of the Monuments, Fine Arts & Archives section of the military, prepare Aristide Maillol's sculpture Baigneuse à la draperie, looted during World War II for transport to France. Sculpture is labeled with sign: Wiesbaden, no. 31."[14]

Jewish art collectors whose artworks by Maillol were looted by Nazis include Hugo Simon,[15] Alfred Flechtheim[16] and many others. Works[edit]

Action in Chains (1905)

Flora, Nude (1910)

L'Été sans bras (1911)

Bathing Woman with Raised Arms (1921)

Nymph (1930)

The Mountain (1937)

L'Air (1938)

The River (1938–43)

• Mme Henry Clemens van de Velde (c. 1899)

Aristide Maillol, The Night, (1920), Stuttgart

https://en.wikipedia.org/wiki/Aristide_Maillol#/media/File:Aristide_Maillol_la_nuit_1902-1.jpg

https://en.wikipedia.org/wiki/Aristide_Maillol Air cast 1938, lead, 130 cm × 240 cm × 93.3 cm (50 in × 94 in × 36+3⁄4 in), Kröller-Müller Museum https://en.wikipedia.org/wiki/Air_(Maillol)

Air is a lead or bronze sculpture, by Aristide Maillol.

He modeled Dina Vierny in plaster in 1938, and casts were made after his death. It is an edition of six.[1] Examples are located at the Kröller-Müller Museum, Yale University Art Gallery, Jardin des Tuileries, J. Paul Getty Museum,[2] Norton Simon Museum,[3] and Kimbell Art Museum.[4] Sotheby’s Geek Week

20–28 July | New York 

Sotheby’s Science & Popular Culture department is thrilled to hold its second ever “Geek Week,” a series of sales reflecting some of the department’s most exciting categories, from dinosaurs, to space exploration, to meteorites, minerals, and more, this years’ “Geek Week” is set to be one of the most exciting weeks of the year.

Sotheby’s "Self Reflected" —a giant, dynamic 23k gold microetching depicting neural activity in the human brain Dr. Greg Dunn in collaboration with Dr. Brian Edwards

https://www.sothebys.com/en/buy/auction/2022/self-reflected/self-reflected-a-giant-dynamic-22k-gold?locale=en

1

29 July 2022•New York

Dr. Greg Dunn in collaboration with Dr. Brian Edwards

"Self Reflected" —a giant, dynamic 23k gold microetching depicting neural activity in the human brain

Monumental Item

Estimate:

1,000,000 - 1,500,000 USD

Description

Self Reflected, 2019-2022.

23k handmade gilded microetching in 25 panels mounted together in custom frame, together measuring just over 8 feet tall, and 10 feet 7 inches wide, and weighing approx. 300 lbs (136 kg). Number 1 of an edition of 3.

Offered together with "The Crescent", a highly specialized lighting structure containing 1,596 high-powered LEDs, which produce up to 15 thousand lumens, measuring approximately 15 1/2 feet in length, and weighing approx. 200 lbs (91 kg) and two remote controls. For a complete list of the lighting programs, please email science@sothebys.com.

Please note that optimal display of Self Reflected requires a ceiling height of at least 15 feet (5 meters) in order to hang the microetching and the light bar.

Self Reflected offers an unparalleled insight of the brain into itself, revealing through a technique called reflective microetching the enormous scope of beautiful and delicately balanced neural choreographies designed to reflect what is occurring in our own minds as we observe this work of art.

Bayer What is gene editing? A (adenosine), C (cytosine), G (guanine), and T (thymine) CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)

Bayer

Gene editing is a groundbreaking technology that enables unprecedented therapeutic approaches in the field of cell and gene therapies. But how exactly does it work? Learn more here.

Good to Know

What is Gene Editing?

https://www.bayer.com/en/news-stories/what-is-gene-editing?fbclid=IwAR0DuWDULVNUoHAukHW_1Jdx5IKLdpOjyLZAx_m2rrPo1xJ2zh42tAdsWRE The next frontier for medicine, cell and gene therapy, is designed to treat disease at its source by making changes to the body’s basic set of instructions or restoring the body’s functionality by replacing damaged tissue. One groundbreaking area of focus is gene editing, a technique that allows scientists to, for example, correct faulty genes that cause a specific disease, thereby aiming to reverse certain disease symptoms or prevent the disease from occurring in the first place.

Bayer Global 

What is gene editing?

https://youtu.be/htz6HN2DMgM A Delicate Editing Tool for DNA 

Gene editing encompasses many different tools and technologies, but the end-goal is the same: to address the root cause of a disease instead of managing its outcome, i.e., the symptoms. Changing genes outside of the body (ex vivo) involves modifying cells - either from the patient or from a donor - to correct genetic mutations or provide new functionalities, and then transplanting them into the patient.1 In vivo gene editing involves the modification of genes in cells while they are inside the body.1 This is a rapidly evolving field utilizing different technologies. The most widely used approach acts like a pair of “molecular scissors” enabling scientists to cut the DNA sequence at a specific spot and then correct, replace, or remove the faulty pieces of DNA.

Gene editing: A biomedical “swiss army knife”

Our DNA is comparable to the world’s biggest code book, containing words made up only of four basic letters – A (adenosine), C (cytosine), G (guanine), and T (thymine) – which, arranged correctly, provide instructions for making proteins.2 The DNA double helix in humans consists of three billion specific arrangements of these letters, and a single “typo” in that sequence can often be the cause for one of the more than 4,000 rare, monogenic, sometimes life-threatening diseases.3 

 CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is an efficient and versatile cutting-edge gene editing tool. By finding a specific stretch of DNA inside a cell, binding to it, and then precisely cutting the DNA at a defined location, it can induce the desired DNA sequence changes in the cell. This is why some scientists liken the technology to a “find and replace” or “backspace key” - capable of editing a single letter in a long genetic sequence. Other gene editing technologies are able to increase or decrease gene expression, install or remove DNA sequences, or switch specific genes on or off. That’s why gene editing could be compared to a “swiss army knife” with multiple tools that can perform different tasks.  Touch Of Heaven - Hillsong Worship https://youtu.be/nxxr47zEUxE

King of Kings (Live) - Hillsong Worship https://youtu.be/dQl4izxPeNU

[tomasorban]

Did the ancients somehow know about DNA?

Conventional history tells us that the double-helix structure and base-pairing characteristic of the DNA molecule was not "discovered" until the twentieth century, based upon the work of scientists Rosalind Franklin, Raymond Gosling, James Watson, Francis Crick, and Erwin Chargaff, primarily in the 1950s and 1960s.

Erwin Chargaff (1905-2002) in particular was responsible for the insight that DNA molecules contain roughly equal proportions of adenine and thymine (one of the "base pairs" in the DNA molecule) and of guanine and cytosine (the other "base pair").  Since that time, high school students everywhere have had to memorize the letters A-T and G-C in conjunction with their introduction to the molecular structure of DNA.

It is fascinating to note that the first four signs of the zodiac wheel after the ecliptic "crossing" of the celestial equator at the spring equinox (shown in the diagram above) are Aries, Taurus, Gemini and Cancer (readers who astutely note that the motion of precession has long ago "delayed" the sky and moved the constellation Pisces into the heliacal rising position once occupied by the constellation Aries during the Age of Aries should note that in astrological terms, the "signs" are considered to remain in the positions shown above, for cogent reasons that are beyond the scope of this particular post).

Is it mere "coincidence" that the base pairs of the DNA molecule begin with the same four letters as the first four signs in the zodiac (A, T, G and C), and that they actually "pair" in a manner consistent with the order of the zodiac signs (A with T, and G with C, just as Aries is next to Taurus and Gemini next to Cancer)?

Of course, skeptical readers will note that the names for the DNA nucleobases were generally given by different researchers operating in different decades during the mid- to late-1800s, and that their names almost certainly were not chosen in order to relate in any way to the zodiac signs (adenine, for example, was named after the pancreas, from which the first samples in which adenine was isolated were taken and which organ in Greek is named aden, while guanine is apparently named after the word for bird droppings or guano).  And so it would seem on the surface that the connection between the zodiac and our modern understanding of the DNA molecule and its structure and base pairing is purely coincidental.  

Nevertheless, even if no plausible argument can be made for an actual connection between the letters A-T-G-C in the DNA molecule, and the letters A-T-G-C in the first four constellations of the zodiac cycle, it certainly seems to be a singular example of serendipity, synchronicity, or the collective unconscious working itself out over the course of thousands of years.

Further, while the letters A-T-G-C may not be among the evidence which argues for ancient understanding of the DNA molecule long before the work of Franklin and Gosling, Watson and Crick, and that of Erwin Chargaff, there is in fact other evidence which suggests that the ancients did in fact display flashes of insight which make us wonder whether they might somehow have had inexplicable knowledge of the importance of the DNA molecule, and even the structure of DNA.

One oft-cited example is the fact that the ancient symbol of the caduceus features two intertwined serpents very reminiscent of the double-helix structure of DNA.  Further, some ancient art including the images from ancient Sumer and Babylon depicted on this page (disregard the discussions of "Nibiru," "Planet X," and the "Annunaki" as outside the scope of this particular post as well) clearly seem to be very suggestive of modern understanding of the structure of DNA.

Jeremy Narby, author of Cosmic Serpent: DNA and the Origins of Knowledge has an interview on the web located here in which he discusses a theory which attempts to explain how the mankind may have acquired knowledge of the importance of DNA and its helictical structure long before the advent of "modern science."  He believes that it is very possible -- and that in fact there is evidence to conclude -- that shamanic techniques can give human beings access to knowledge which modern scientific methods only confirmed much later, in recent decades.  In fact, he notes that shamans regularly describe visions involving intertwining serpents, and associate these serpents with something shared by all the multifarious life-forms in our world. In the interview, he makes the assertion that:

Both shamans and molecular biologists agree that there is a hidden unity under the surface of life's diversity; both associate this unity with the double helix shape (or two entwined serpents, a twisted ladder, a spiral staircase, two vines wrapped around each other); both consider that one must deal with this level of reality in order to heal.  One can fill a book with correspondences between shamanism and molecular biology.

Note that in an image about four-fifths of the way down that long web page, Dr. Narby includes an image from the tradition of western alchemy which he believes has clear resemblance to chromosonal DNA, and which certainly predates the work of Franklin, Gosling, Watson and Crick by centuries.

There is other evidence, particularly from ancient sacred traditions and mythology, which strongly suggest that mankind somehow knew far more about the importance of DNA than we moderns have been led to believe. This evidence will be addressed in my next book.

This evidence has nothing (directly) to do with the synchronicity involving the letters A-T-G-C and the first four signs of the zodiac, although the ancients clearly taught that mankind reflected the cosmos on a "microcosmic" level, a concept discussed in previous posts such as "

The extra-zodiacal decans in macrocosm and microcosm," "

More on macrocosm and microcosm

Human internal organs connected to solar system planets?

Okeanos

The judgement of Paris

Giordano Bruno, 1548-1600

If each strand of our DNA is composed of base pairs whose initials reflect the initials of those first four zodiac signs (each of which is considered the "leader" of a grouping of three other signs, categorized as the Earth, Air, Fire, and Water signs of the zodiac), then we can truly say that -- however the serendipitous confluence came about, the naming of the DNA base pairs symbolizes on a profound level the fact that each of us embodies a tiny cosmos.

addendum:

DNA has the geometry of ten interpenetrating dodecahedra spiraling along the helix. It requires ten Phi spirals to create the top view of DNA. The basic geometry of DNA is that of a dodecahedron. Since Daniel Winter assumes that the universe is one huge super hologram and that everything in the universe is connected with everything else by means of Golden waves, he believes that DNA is electro-magnetically coupled with the Earth grid and the Zodiac by means of the fractal dodecahedron shapes of energy.