#the likelihood of an autoimmune disease

[mizugucci]

soooo i may have an autoimmune disease ?

[jimmystrudel]

I hate remembering that when I have a baby I'll need to feed them gluten until proven they have an issue, otherwise they will develop an intolerance

[chefkids]

Spoon Theory

This is arguably the single most important The Bear meta post I will ever make so please bear with me.

The first spoon we see in the entire series is when Carmy takes Sydney's spoon to try her stew. This is right after he cut his hand from not being able to find his sharp knife, and before he has to meet with Natalie to get Mikey's jacket, which was stressing him out. She "gave him a spoon" and a bit of positivity when he needed to calm down and get some energy by knowing at the very least Sydney can cook well.

Needing a spoon is needing help. When he hands over the brigade to Sydney he is waving around spoons the entire episode, when she really needed his help and his "spoons". Later on Sydney is not afraid to just ask him for his help.

With the risotto she gave him a "spoon" that would help the restaurant, that brought in a good review and customers, but he didn't have enough of his own "spoons" to deal with it as he was stressing out over the window that just got shot through and the IRS needing the missing tax returns. Right before trying the risotto Carmy had told Richie he is afraid of something good happening. He is afraid of Sydney and him doing well, because the better it gets the more it will hurt him when something goes wrong. That is why he keeps self sabotaging the restaurant and doubting Sydney.

After Sydney quit, she is still using her spoons for mental energy to make sure Marcus is okay and to try and figure out her next steps career wise. Carmy grabbed a spoon to open the tomato can lid, which he really didn't need because he could've just used the can opener, and then found the money. When he finds the money they both know they would be fine on their own, she could find another job, he could fix up The Beef. But they still need each others emotional spoons to achieve their passions, so he reaches out and she comes back.

In Season 2 she did need his "spoons" to help create the menu and decide on the details for the restaurant, but he barely gave her any because he was still so caught up in his past trauma and the literal and metaphorical forks in his life.

Fixing the table really didn't physically need more than one "spoon"/person. But he needed her there to work through his mental block. With the inspiration food tour, she did it on her own and she didn't physically need him for it, she needed his emotional spoons.

When they are not communicating well with each other and Carmy is trying to reach back and be involved again, he gets as close as he can to her spoon without actually using it.

And now the dark side of spoons.

The originator of spoon theory has lupus and first came up with this theory at a restaurant to explain what it was like living with the condition to a friend. They could've easily said Sydney's mom died of cancer or an accident or anything else. But this is all so intentional, out of all the things it is Lupus. I don't want Sydney to be sick as much as the next person, but Lupus is a chronic autoimmune disease that has higher likelihood of developing when you have a family member with it, and can be triggered by environmental factors such as stress. It is an invisible illness and Christine's own handle is butyoudontlooksick, which could really explain Sydney and what she has going on behind her walls that people can't see. She has been a rock to so many people and over exerting herself, but there might come a time soon when Sydney will genuinely need other peoples "spoons", especially Carmy's, because she's all out.

Now that Carmy said he is choosing to give Syd his focus aka his "spoons", will he actually be able to follow through?

Read The Fork Theory next

Read The Knife Theory

[covid-safer-hotties]

Also preserved in our archive

By John Jesitus

A population-based study has shown a slightly elevated risk for patients’ developing skin disorders, including alopecia areata (AA), alopecia totalis (AT), vitiligo, and bullous pemphigoid (BP), more than 6 months after COVID-19 infection. In addition, the authors reported that the COVID-19 vaccination appears to reduce these risks.

The study was published in JAMA Dermatology on November 6.

‘Compelling Evidence’ “This well-executed study by Heo et al. provides compelling evidence to support an association between COVID-19 infection and the development of subsequent autoimmune and autoinflammatory skin diseases,�� wrote authors led by Lisa M. Arkin, MD, of the Department of Dermatology, University of Wisconsin School of Medicine and Public Health in Madison, Wisconsin, in an accompanying editorial.

Using databases from Korea's National Health Insurance Service and the Korea Disease Control and Prevention Agency, investigators led by Yeon-Woo Heo, MD, a dermatology resident at Yonsei University Wonju College of Medicine, Wonju, Republic of Korea, compared 3.1 million people who had COVID-19 with 3.8 million controls, all with at least 180 days’ follow-up through December 31, 2022.

At a mean follow-up of 287 days in both cohorts, authors found significantly elevated risks for AA and vitiligo (adjusted hazard ratio [aHR], 1.11 for both), AT (aHR, 1.24), Behçet disease (aHR, 1.45), and BP (aHR, 1.62) in the post-COVID-19 cohort. The infection also raised the risk for other conditions such as systemic lupus erythematosus (aHR, 1.14) and Crohn’s disease (aHR, 1.35).

In subgroup analyses, demographic factors were associated with diverse effects: COVID-19 infection was associated with significantly higher odds of developing AA (for both men and women), vitiligo (men), Behçet disease (men and women), Crohn’s disease (men), ulcerative colitis (men), rheumatoid arthritis (men and women), systemic lupus erythematosus (men), ankylosing spondylitis (men), AT (women), and BP (women) than controls.

Those aged under 40 years were more likely to develop AA, primary cicatricial alopecia, Behçet disease, and ulcerative colitis, while those aged 40 years or older were more likely to develop AA, AT, vitiligo, Behçet disease, Crohn’s disease, rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, ankylosing spondylitis, and BP.

Additionally, severe COVID-19 requiring intensive care unit admission was associated with a significantly increased risk for autoimmune diseases, including AA, psoriasis, BP, and sarcoidosis. By timeframe, risks for AA, AT, and psoriasis were significantly higher during the initial Delta-dominant period.

Vaccination Effect Moreover, vaccinated individuals were less likely to develop AA, AT, psoriasis, Behçet disease, and various nondermatologic conditions than were those who were unvaccinated. This finding, wrote Heo and colleagues, “may provide evidence to support the hypothesis that COVID-19 vaccines can help prevent autoimmune diseases.”

“That’s the part we all need to take into our offices tomorrow," said Brett King, MD, PhD, a Fairfield, Connecticut-based dermatologist in private practice. He was not involved with the study but was asked to comment.

Overall, King said, the study carries two main messages. “The first is that COVID-19 infection increases the likelihood of developing an autoimmune or autoinflammatory disease in a large population.” The second and very important message, he added, is that being vaccinated against COVID-19 provides protection against developing an autoimmune or autoinflammatory disease.

“My concern is that the popular media highlights the first part,” said King, “and everybody who develops alopecia areata, vitiligo, or sarcoidosis blames COVID-19. That’s not what this work says.”

The foregoing distinction is especially important during the fall and winter, he added, when people getting influenza vaccines are routinely offered COVID-19 vaccines. “Many patients have said, ��I got the COVID vaccine and developed alopecia areata 6 months later.’ Nearly everybody who has developed a new or worsening health condition in the last almost 5 years has had the perfect fall guy — the COVID vaccine or infection.”

With virtually all patients asking if they should get an updated COVID-19 vaccine or booster, he added, many report having heard that such vaccines cause AA, vitiligo, or other diseases. “To anchor these conversations in real data and not just anecdotes from a blog or Facebook is very useful,” said King, “and now we have very good data saying that the COVID vaccine is protective against these disorders.”

George Han, MD, PhD, associate professor of dermatology at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell in Hempstead, New York, applauds investigators’ use of a large, robust database but suggests interpreting results cautiously. He was not involved with the study but was asked to comment.

“You could do a large, well-done study,” Han said, “but it could still not necessarily be generalizable. These autoimmune conditions they’re looking at have clear ethnic and racial biases.” Heo and colleagues acknowledged shortcomings including their study population’s monomorphic nature.

Additional issues that limit the study’s impact, said Han, include the difficulty of conceptualizing a 10%-20% increase in conditions that at baseline are rare. And many of the findings reflected natural patterns, he said. For instance, BP more commonly affects older people, COVID-19 notwithstanding.

Han said that for him, the study’s main value going forward is helping to explain a rash of worsening inflammatory skin disease that many dermatologists saw early in the pandemic. “We would regularly see patients who were well controlled with, for example, psoriasis or eczema. But after COVID-19 infection or a vaccine (usually mRNA-type), in some cases they would come in flaring badly.” This happened at least a dozen times during the first year of post-shutdown appointments, he said.

“We’ve seen patients who have flared multiple times — they get the booster, then flare again,” Han added. Similar patterns occurred with pyoderma gangrenosum and other inflammatory skin diseases, he said.

Given the modest effect sizes of the associations reported in the Korean study, Arkin and colleagues wrote in their JAMA Dermatology editorial that surveillance for autoimmune disease is probably not warranted without new examination findings or symptoms. “For certain,” King said, “we should not go hunting for things that aren’t obviously there.”

Rather, Arkin and colleagues wrote, the higher autoimmunity rates seen among the unvaccinated, as well as during the Delta phase (when patients were sicker and hospitalizations were more likely) and in patients requiring intensive care, suggest that “interventions that reduce disease severity could also potentially reduce long-term risk of subsequent autoimmune sequelae.”

Future research addressing whether people with preexisting autoimmune conditions are at greater risk for flares or developing new autoimmune diseases following COVID-19 infection “would help to frame an evidence-based approach for patients with autoimmune disorders who develop COVID-19 infection, including the role for antiviral treatments,” they added.

The study was supported by grants from the Research Program of the Korea Medical Institute, the Korea Health Industry Development Institute, and the National Research Foundation of Korea. Han and King reported no relevant financial relationships. Arkin disclosed receiving research grants to her institution from Amgen and Eli Lilly and Company, personal fees from Sanofi/Regeneron for consulting, and personal consulting fees from Merck outside the submitted work. Another author reported personal consulting fees from Dexcel Pharma and Honeydew outside the submitted work. No other disclosures were reported.

Study Link: jamanetwork.com/journals/jamadermatology/article-abstract/2825849 (PAYWALLED)

[ask-philgraves]

Cassie here!

Y'all probably have seen that I haven't been around a whole bunch, answering asks only occasionally and roleplaying as well.

Well, that is because my autoimmune disease flared up again, and while I'm looking for jobs, I'm prioritizing that over this blog for the moment.

Because of this, I'm having Rhi and Spooks sort of let me know what times would be good for people so we can still have that talk and plan out the organization. Don't worry that will still definitely happen. It will be taking place over Microsoft Teams I do believe.

So, because my autoimmune disease is flaring up, and I am disabled, I do wanna talk about my particular flavor of Autoimmune because everyone has something different. If you get squeamish, or pity me, then don't read further. I promise I'm fine, I know how to manage my disease, and at 21 there's not a whole lot I can do regarding medicine and treatment unless I truly want to fuck myself over in the long run.

So, my specific type of Auto-Immune disease is called Undifferentiated Connective Tissue Disease, or UCTD for short. It's a very long and medical sounding thing, but it basically means that what I have doesn't fit any KNOWN inflammatory arthritis, but they have deemed it an inflammatory arthritis. There's too little data (not in my case) for a conclusive result, OR like in my case, there's enough data but my puzzle piece keeps changing and having different symptoms that make it incredibly hard to give me one diagnosis that I fit all the criteria for.

However, my Rheumatologist that just retired, God Bless her, has seen my exact condition only one other time. I am positive for the ANA marker in my blood, which if you don't know, is one marker that they use to see if you have Lupus or a likelihood of developing lupus. In my case, I don't have lupus. Well, kind of.

Lupus is known to attack organs, so things like kidneys, and liver are most commonly known to be affected by it. (Kidneys moreso, but I mention Liver because my family has a history of going into Liver failure after they develop Lupus.) My arthritis however, attacks the connective tissues and eats at them, causing my bones to get creaky and crackle.

So my arthritis, in her own words, is Lupus Lite. It's not attacking my organs, but destroying my muscle mass, ligaments, cartilage, joints and last but not least, my actual bones.

So, it's pretty severe, but thankfully, it's only attacking my connective tissue at the moment. And it's pretty slow moving too. It's mainly in my joints, slowly eating away at the connective tissue there.

Because of the non-severity at the moment, my age, and the fact that I reacted HORRIBLY to one of the immunosuppressants they commonly use for cases like mine, my doctor and I have both decided that unless it starts getting horribly worse, or transforming into full blown lupus (which she has seen before), that we're just going to medicate the symptoms rather than the disease itself.

So, what exactly does that mean? Well, it means drinking caffeine when I'm super fatigued and exhausted, along with protein shakes. It means taking Celebrex when my joints start to become swollen and inflamed so I can move them without them feeling like they're in glue. It means when I have memory issues, we're going to take a day off work so I don't bother with the flow of things. (What if I accidentally give a customer the wrong order? Or I forget entirely what I was doing and try to go home in the confusion? Things like this make it to where I need to stay home occasionally.)

Now, that's not the only part of my condition that's affecting me as well. Because my brain is so hardwired to processing high amounts of pain, it gets a little weird. Hence, my second condition, very well known to many. Fibromyalgia. My specific kind, is when my brain is so used to processing pain and receiving pain, that it actually hurts itself when there isn't any pain. It processes pain as still there, or lingering, or maybe perhaps even stronger than what it technically is.

This can make it hard if I cut myself or burn myself while cooking. I can't tell off of pain when I should go to the doctor, because a small papercut can feel like my entire hand is on fire. Does it usually, no. But it definitely can. So instead, I have to learn how wounds look and because I'm in the USA, treat them myself most of the time.

Fibro also causes brain fog, and lingering pain. Imagine getting punched in the arm, and you felt it for the next 6 hours. That's the kind of thing that happens! A small poke in your back might briefly hurt you, but to me, it could cause my muscles to tense up and feel pain for the next 2 hours.

Well, if you have so much wrong with you, wouldn't it be easier to file for disability?

You would think so. In any other (first-world) country, I could probably file for disability and never have to work again. However in the USA, filing for disability is practically pulling teeth and locking yourself into poverty for the rest of your life. At no time can you have financial assets above 2000 dollars, so you are constantly on the verge of being homeless.

If you get above 2k, even 2001, you are instantly cut off from payments that the government hands out. Which can vary from 800$ a month to 1k. If they deem your disability bad enough.

On top of that, in certain cases, the government won't allow you to get married or you lose your disability benefits. Which is what many people rely on to survive.

So... Essentially you are forced to work until you are too sick to work?

Yes.

This is going to get slightly political, but this is why people are wanting to upheaval the government. It doesn't work, even for it's most compromised civilians. I shouldn't have to pay out of pocket for my care that checks if I'm going to get Lupus or not. My family shouldn't have been denied disability when dying of stage four pancreatic cancer. My grandma should be able to marry my grandpa, and I should be able to marry my boyfriend. Without them losing their benefits.

I shouldn't have to work if I very clearly am struggling to perform basic tasks.

However, there's a limelight at the end of the tunnel.

Since my conditions aren't bad enough yet... I can still make a career for myself. So, big life update, I'm going to be going to University either this fall or the upcoming winter semester. I'm gonna become a Veterinarian, Specifically Oncology (So pet cancer.) I'm gonna do my best, and save up as much as I can so I can help myself and my family out. It's aggravating, to say the least. But, I've been through worse, so I try to stay positive. That helps my pain a lot too.

That's all for now, I should be posting in a few days as my flareup stops being a lil bitch. You're welcome to send asks, or messages. I promise I'll get to all of them soon. Bye for now!!

[johnnyslaughtr]

being physically disabled at a young age is such a weird thing. i’ve got a level of perspective that most people don’t but my god is it hell to navigate the world as a young disabled person. for years i’ve been told that i’m too young to have a physical disability only for doctors to now think i have an autoimmune disease that is causing insane levels of pain across my body. i wasn’t lying about it and surprise it had nothing to do with my weight.

i use a cane to get around because i currently can’t afford anything that would be better suited and i get such weird looks. a doctor asked me if i really needed it and who told me i needed it— i don’t walk around with a cane for shits and giggles, i told myself i needed it because walking without support was becoming unbearable. in likelihood i probably am going to need a wheelchair at some point but ill cross that bridge when i get to it.

before i became estranged from my family i was constantly being met with their own internalised ableism. they’re both physically disabled but i was constantly told that i was over exaggerating or i was making it up because i was between the ages of 14-22 (im 22 currently) and god forbid i complain about my pain and my disability when they have it so much worse. it’s bullshit i am allowed to complain.

my uni was weird initially about me claiming i had a disability, mostly because i didn’t have a definitive diagnosis other than generalised chronic pain. but i continued to push and win for me, i got a ground floor flat so i no longer have to walk up three flights of stairs (because for some reason this building doesn’t have a lift???)

i guess i wanted to sort of write this all out because life is complex as a young physically disabled person (and i have mental disabilities on top of that lol) i’m proud of myself for getting where i am all things considered but i wish i had answers to what is really going on with my body, i wish people took me seriously and i wish i wasn’t relying on pain medication to get through my day.

sorry for the long post and i’m sure like no one is going to read through it all 😭 but i suppose i just wanted to write it out

[chuckabeth]

I don’t know why I’ve suddenly been imbued with the audacity of actually writing a real tumblr post instead of just reglobbing but um

On behalf of myself and all immunocompromised people

PLEASE GET YOUR SHOTS THIS SEASON

Please

I didn’t used to exempt myself from seasonal vaccines. I don’t even want to, I don’t even like it. But my body’s defenses and reactions are so frail and inflamed that if I take the shot, I will get sick. Really sick. Probably weeks of real pain and illness and slow recovery overreacting to the vaccine, and it will cost me my grades, my social life, my mental health, and that’s when a billion different logistical and health hurdles are already threatening my tenuous hold on those things as it is. I have to work so hard, and make decisions so, so carefully just to maximize the possibility that I’ll hopefully! Hopefully. Be well. Or at least well enough.

I have misunderstood and untreatable autoimmune disease(s) that have (in all likelihood) damaged my organs and decreased my ability to digest food and absorb vitamins on my own. I’m already in so much pain and fatigue every day that I (thank the Lord that I have this resource) use a wheelchair to help me get around without making myself sicker just from the strain of doing the regular stuff.

I have had COVID at least once. Thankfully I had taken the vaccine that time. But the vaccine reaction was almost as bad as the real thing. BUT if you’re healthy, (or at least healthier than me) THIS WILL NOT BE TRUE FOR YOU. You can afford a couple days of feeling a little under the whether. Right? I feel under the weather or worse literally every day of my friggin life, and often I just get on with things.

So…. Do it for me? So I don’t get long COVID? Or just like, the flu? Or other things that are popping up! Wear a mask and stay home if you can when you’re sick, thoughI know the latter is very difficult to get away with for so many. I just ask because these things could actually damage me in ways they might not damage you. And if you don’t do it for me, do it for the people that could just be straight up killed by a respiratory illness. That stuff spreads so easily, and they are likely locked up in their houses just as painfully as you were in lockdown trying to stay alive. Yet, like you, they have lives and hopes and dreams and are worthy of human decency and care and respect. But believe me, we don’t often feel enough of it, let alone from our doctors. All too often not even from our own families.

Or, you know, like, do it for yourself and other able bodied people who could suddenly find yourselves in our position through this Long COVID stuff. I know!! I know it feels like naw that would never happen to you. Is this stuff even for real? But trust me trust me, it can, it will. A lot of us sickies were like you once. And a lot of us still don’t have answers for what “went wrong.” And realizing that none of us are all that different, that we’re al in this together actually! Is one of the first biggest steps to compassionate and real, noticeable change. Caring enough about others and their needs enough to be mindful about simple stuff.

And hey, MAYBE just on your own, none of it will be enough. But at least you can look back and comfort yourself saying you tried. You didn’t take our lives for granted.

LOL anyway I’m just so nervous about school this winter please help me get my bachelor’s in as much peace as possible

[ren-is-ur-gfriend]

Reasons to not have kids:

* Increased likelihood of autoimmune disease

* Pelvic floor dysfunction

* Diastasis recti

* Depression

* Anxiety

* Postpartum psychosis

* Choriocarcinoma

* Pregnancy is not representative of a woman!!

* Takes 7 years for your body to recover

P.s: the list goes on :)

[ladyfarona]

Had my doctor run an ANA blood test on Monday. Haven't heard back from her personally but the results posted online are showing a hiiiigh likelihood I have some kind of autoimmune disease(s), ya know, like lupus. 🙃

[anjaliverma123]

Pregnancy : Risks and Complications

Pregnancy is often depicted as a time of joy and anticipation, but it's also a period that comes with its own set of risks and potential complications. While many pregnancies proceed smoothly, it's essential for expectant parents to be aware of the various risks and complications that can arise during gestation. Understanding these factors can help individuals navigate their pregnancy journey more confidently and make informed decisions about their prenatal care. In this blog post, we'll explore some of the common risks and complications associated with high - risk pregnancy, along with preventive measures and potential treatments.

Understanding Pregnancy Risks

Pregnancy involves numerous physiological changes in a woman's body, aimed at supporting the development of a growing fetus. While these changes are natural and necessary, they can also increase the likelihood of certain health risks and complications. Some of the key factors contributing to pregnancy risks include:

Maternal Age

Advanced maternal age (typically defined as 35 years and older) is associated with an increased risk of various pregnancy complications, including gestational diabetes, preeclampsia, and chromosomal abnormalities such as Down syndrome.

Pre-existing Medical Conditions

Women with pre-existing medical conditions such as diabetes, hypertension, thyroid disorders, or autoimmune diseases may face additional challenges during pregnancy. These conditions can exacerbate pregnancy-related complications and require close monitoring by healthcare providers.

Lifestyle Factors

Smoking, alcohol consumption, substance abuse, and poor nutrition can all contribute to pregnancy risks. These factors not only affect maternal health but can also negatively impact fetal development and increase the likelihood of birth defects and other complications.

Common Pregnancy Complications

Despite advances in prenatal care, certain complications can arise during pregnancy, posing risks to both the mother and the developing baby. Some of the most common pregnancy complications include:

Gestational Diabetes

Gestational diabetes occurs when blood sugar levels rise during pregnancy, leading to potential complications such as macrosomia (large birth weight), preterm birth, and an increased risk of cesarean delivery. Proper management through diet, exercise, and medication is essential to minimize risks to both mother and baby.

Preeclampsia

Preeclampsia is a serious condition characterized by high blood pressure and signs of organ damage, typically occurring after 20 weeks of pregnancy. If left untreated, preeclampsia can lead to complications such as eclampsia (seizures), placental abruption, and maternal/fetal death. Close monitoring and prompt medical intervention are crucial for managing preeclampsia.

Preterm Labor

Preterm labor, or premature birth, refers to the onset of labor before 37 weeks of pregnancy. Premature infants may face various health challenges, including respiratory distress syndrome, developmental delays, and long-term disabilities. Identifying risk factors and receiving appropriate prenatal care can help reduce the likelihood of preterm labor.

Miscarriage

Miscarriage, or spontaneous abortion, refers to the loss of a pregnancy before 20 weeks gestation. While miscarriages are relatively common, experiencing recurrent miscarriages or late-term pregnancy loss can be emotionally devastating for couples. Understanding the potential causes of miscarriage and seeking support from healthcare providers and support groups can help individuals cope with this loss.

Birth Defects

Birth defects are structural or functional abnormalities present at birth, ranging from mild to severe. These abnormalities may result from genetic factors, environmental exposures, or a combination of both. Prenatal testing, including ultrasound scans and genetic screening, can help identify potential birth defects early in pregnancy, allowing for informed decision-making and appropriate medical management.

Preventive Measures and Prenatal Care

While it's impossible to eliminate all pregnancy risks and complications, there are several steps individuals can take to optimize their chances of a healthy pregnancy outcome:

Preconception Planning:

Planning for pregnancy involves optimizing maternal health before conception through regular exercise, a balanced diet, supplementation (e.g., folic acid), and managing pre-existing medical conditions. Consulting with a healthcare provider before conception can help identify and address potential risk factors.

Regular Prenatal Check-ups:

Attending regular prenatal appointments allows healthcare providers to monitor maternal and fetal well-being, identify any potential complications early, and provide appropriate interventions as needed. These appointments typically include physical examinations, ultrasound scans, and laboratory tests to assess maternal and fetal health.

Healthy Lifestyle Choices:

Adopting a healthy lifestyle during pregnancy, including abstaining from smoking, alcohol, and illicit drugs, maintaining a balanced diet, staying physically active (with healthcare provider approval), and managing stress, can help reduce the risk of pregnancy complications and promote optimal fetal development.

Education and Support:

Educating oneself about pregnancy, childbirth, and postpartum care can empower expectant parents to make informed decisions and advocate for their health and the health of their baby. Joining prenatal classes, seeking support from healthcare professionals, and connecting with other expectant parents can provide valuable guidance and reassurance throughout the pregnancy journey.

Conclusion

Pregnancy is a unique and transformative experience, but it's important to recognize that it comes with inherent risks and potential complications. By understanding these risks, taking proactive measures to optimize maternal health, and receiving comprehensive prenatal care, expectant parents can maximize their chances of a healthy pregnancy and childbirth. While some complications may be unavoidable, early detection, prompt intervention, and ongoing support can help mitigate their impact and ensure the best possible outcomes for both mother and baby. Remember, every pregnancy is different, and seeking guidance from healthcare professionals is crucial for personalized care and support throughout the journey to parenthood.

[serioussideblog]

And one time I managed to get a yeast infection AND BV AND a UTI at the same time…and no, I didn’t even do anything to get all that. It literally just happened randomly.

To all vagina owners and also people who have a urinary tract (pretty sure that last one covers everyone): you gotta be careful with those. You got multiple holes next to each other surrounded by skin and usually hair. Also the urethra is where pee comes from and the anus is near there, too, in your gluteal cleft. So you have a lot of likelihood of things going wrong.

Wipe front to back, it reduces risk. No douching. You can gently wash the labia and such with soap but be careful. Follow your doctor’s advice. Change your underwear frequently. And if you start getting symptoms like itching or burning or like you have to pee but can’t or an unusual smell or unusual discharge, see a doctor.

And as for why diabetes can lead to an increased risk of yeast infections: the reason is twofold. One, yeast likes sugar, and when you have diabetes, you have excess sugar, including in your urine (which comes out of your urethra, which is not in the vagina but is the neighbor of the vagina). And two, diabetes and some of the medications used to treat it can cause you to be immune compromised. (If you have type 1 diabetes, that’s an autoimmune disease, and in some cases, you may need to be on immunosuppressive medications. And any type of diabetes can and often will cause damage to other organs and systems in the body, including those involved in fighting off germs and fungi. Yeast is a fungus.)

All this to say, humans have bodies that need their parts watched over, so take care of your body.

Having a vagina honestly sucks bc it's like you have to do fucking alchemy just to prevent yourself from getting sick. You've got an intricate ecosystem of microorganisms down there that you're dependent on for your own well-being and they can be set off by the tiniest fucking thing

Keeping your pubes too short can cause yeast infections, but letting them get too long can also cause yeast infections. Washing the area with specialized soap can help prevent yeast infections, but it can also cause them. Your periods can cause yeast infections, and so can the medicine you take to stop your periods. Having sex can cause yeast infections, especially if the person you're having sex with is diabetic (???). Being diabetic can cause yeast infections. Wearing the wrong clothes or eating the wrong things can cause yeast infections. Not getting enough fucking sleep can cause yeast infections. The list is neverending

Luckily, yeast infections are fairly easy to treat with OTC medicine that you can find at any Walmart. BUT! Even if all of your symptoms indicate that you have a yeast infection, you have to take a test first to confirm that it's a yeast infection (they do not sell the tests at Walmart) bc you might actually have the opposite of a yeast infection (bacterial vaginosis) which has the exact same symptoms as a yeast infection but is caused by an imbalance of different microorganisms. And if you use yeast infection medicine to treat a bacterial infection it will light your pussy on fire. So if you have a bacterial infection, you must instead visit your local witch doctor (gynecologist) and get prescribed special potions (antibiotics) to treat it

Antibiotics can also cause yeast infections

[drankitdaveortho]

Frozen Shoulder: Know The  Causes, Symptoms, and Treatment From The Best Orthopaedic Surgeon In Nairobi

Kimani, a 52-year-old teacher, first noticed the stiffness in his right shoulder when he struggled to reach for a book on a high shelf. Initially, he dismissed it as a minor strain. But over the next few weeks, the pain worsened. Simple tasks like dressing, combing his hair, or even sleeping on his side became excruciating. Frustrated and concerned, Kimani visited a doctor, only to hear the unexpected diagnosis — frozen shoulder.

Frozen shoulder, medically known as adhesive capsulitis, is a condition that causes pain, stiffness, and limited range of motion in the shoulder joint. According to Dr Ankit Dave, one of the best doctors for sports injury in Nairobi, it develops gradually, worsening over time before eventually improving. Though the exact cause remains unknown in many cases, there are clear risk factors and treatment options that can help manage and alleviate the condition.

Causes of Frozen Shoulder

Frozen shoulder occurs when the connective tissue surrounding the shoulder joint, known as the capsule, thickens and tightens, restricting movement. While the exact trigger is unclear, several factors can contribute to its development:

Injury or Surgery: If the shoulder remains immobilized for an extended period due to surgery, fracture, or injury, it increases the risk of frozen shoulder.

Diabetes: Studies show that people with diabetes are more likely to develop frozen shoulder, though the link is not fully understood.

Autoimmune and Inflammatory Conditions: Conditions like rheumatoid arthritis and thyroid disorders may contribute to joint inflammation, leading to stiffness.

Aging: Frozen shoulder is more common in people between the ages of 40 and 60, with women being more affected than men.

Cardiovascular and Neurological Disorders: Stroke, Parkinson’s disease, and heart disease may increase the likelihood of developing frozen shoulder due to prolonged inactivity, warns Dr Ankit Dave, well-known as one of the best doctors for sports injury in Nairobi.

Symptoms of Frozen Shoulder

Frozen shoulder typically progresses in three stages, each lasting several months:

Freezing Stage:

Gradual onset of pain, worsening over time.

Shoulder movement becomes increasingly restricted.

Pain is often worse at night, making sleep difficult.

Frozen Stage:

Pain may decrease slightly, but stiffness remains.

The range of motion is significantly reduced, limiting daily activities.

Muscle weakness may develop due to reduced use of the shoulder.

Thawing Stage:

Gradual improvement in shoulder mobility.

Stiffness begins to decrease, and normal function slowly returns.

The overall recovery process can take from several months to up to three years.

Treatment Options

While frozen shoulder can be painful and frustrating, several treatment options can help speed up recovery and restore movement, explains Dr Ankit Dave — one of the best orthopaedic surgeons in Nairobi.

1. Physical Therapy

Physical therapy is the most effective treatment for frozen shoulder. Gentle stretching and mobility exercises help reduce stiffness and gradually restore movement. Common exercises include:

● Pendulum swings to loosen the joint.

● Cross-body stretches to improve flexibility.

● Shoulder rotations to regain strength and motion.

2. Pain Management

To relieve pain and inflammation, doctors may recommend:

● Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen.

● Corticosteroid injections to reduce severe inflammation.

● Hot and cold therapy to soothe the shoulder muscles.

3. Hydrodilation

This procedure involves injecting sterile fluid into the shoulder capsule to stretch and loosen the tissue. It is often used when physical therapy alone is not enough.

4. Manipulation Under Anesthesia (MUA)

In severe cases, doctors may manipulate the shoulder joint while the patient is under anesthesia. This helps break up scar tissue and improve mobility.

5. Surgery

If conservative treatments fail, arthroscopic surgery may be recommended. Surgeons remove scar tissue and adhesions to restore movement. However, surgery is usually the last resort.

Preventing Frozen Shoulder

While not all cases can be prevented, the following steps can reduce the risk:

● Keep moving: Avoid prolonged shoulder immobility after injury or surgery.

● Stretch regularly: Gentle stretching exercises maintain flexibility.

● Manage underlying conditions: Properly managing diabetes, thyroid disorders, or other chronic illnesses can lower the risk.

Conclusion

Frozen shoulder is a painful and limiting condition, but with proper treatment and patience, recovery is possible. Just like Kimani, who dedicated himself to physical therapy and pain management, most individuals regain their full range of motion over time. If you experience persistent shoulder pain and stiffness, seeking early medical intervention from the best orthopaedic surgeons in Nairobi can prevent the condition from worsening and improve the chances of a faster recovery.

[thereseduane]

Early Detection in Complicated Skin and Soft Tissue Infections

Complicated skin and soft tissue infections (cSSTIs) are a leading cause of hospitalization, particularly among individuals with underlying health conditions. These infections, ranging from abscesses to severe forms like necrotizing fasciitis, pose serious risks when not promptly managed. Early detection is crucial to preventing complications such as sepsis, tissue necrosis, organ failure, and even amputations. Timely diagnosis and intervention improve patient outcomes and reduce strain on healthcare systems.

cSSTIs encompass cellulitis, diabetic foot infections, infected surgical wounds, and necrotizing fasciitis. They often begin as localized infections but can rapidly progress into deep tissue involvement, making early identification essential. The primary distinction between uncomplicated and complicated infections lies in the depth of tissue involvement, comorbidities, and overall severity.

While uncomplicated infections may resolve with basic treatment, cSSTIs demand aggressive and targeted care. Vulnerable populations, including individuals with diabetes, compromised immune systems, or advanced age, face increased risk. For example, poorly controlled blood sugar in diabetic patients impairs wound healing and increases the likelihood of infection progression. The first 48 hours after infection often dictate the disease's progression, making rapid intervention essential.

Detecting cSSTIs early allows for less invasive treatments, such as targeted antibiotics and minor surgical procedures. Clinicians rely on physical signs like redness, swelling, and warmth alongside imaging tools such as ultrasonography, CT scans, or MRIs to assess infection depth. Microbiological tests, including wound cultures and PCR assays, guide antibiotic selection and reduce the risk of resistance. Increasing awareness of subtle clinical indicators, particularly in non-traditional settings like urgent care centers, can improve early recognition.

Despite these benefits, diagnosing cSSTIs presents challenges. Symptoms may mimic those of inflammatory or non-infectious conditions, complicating clinical judgment. In some cases, patients may not show typical signs of infection, especially when immunocompromised or affected by chronic illnesses like obesity or diabetes. Conditions like venous stasis dermatitis or autoimmune skin disorders can present similarly, leading to delayed or misdirected treatment.

Limited access to advanced diagnostics in certain healthcare settings can hinder timely identification. Addressing these barriers through expanded diagnostic access and stronger interprofessional collaboration is essential for early and accurate diagnosis.

Once the infection is identified, prompt intervention becomes the cornerstone of care. Antibiotic therapy, tailored through microbial analysis, helps control infection spread and mitigate resistance. Studies consistently show that early treatment reduces complications, shortens hospital stays, and lowers mortality rates.

In addition to medication and surgical intervention, advanced wound care techniques, such as vacuum-assisted closure (VAC) therapy or specialized dressings, can accelerate healing and prevent reinfection. VAC therapy works by applying negative pressure to the wound, promoting granulation tissue formation, improving blood flow, and reducing edema. It is beneficial for deep or chronic wounds where standard dressings may be insufficient.

Ongoing monitoring following treatment initiation is vital to ensure recovery and detect any setbacks. Regular follow-up in hospital and outpatient settings enables timely adjustments to care plans. Patient education on recognizing warning signs, such as fever, increased pain, or swelling, empowers individuals to seek help before complications arise.

Educating patients on proper wound hygiene, medication adherence, and when to escalate care improves engagement and long-term outcomes. Misconceptions about infection severity or reluctance to report symptoms can delay follow-up, underscoring the need for clear communication between care teams and patients.

By strengthening diagnostic capabilities, initiating antimicrobial treatment swiftly, and applying appropriate surgical and wound care strategies, healthcare providers can significantly reduce the burden of cSSTIs. Continued monitoring and patient engagement support long-term recovery, lowering the likelihood of recurrence or life-threatening complications.

[vijayanmaster]

Alopecia Areata in Children: Early Signs, Diagnosis Challenges, and Tailored Treatment Approaches

Alopecia areata is an autoimmune condition where the body’s immune system mistakenly attacks hair follicles, resulting in hair loss. While it can affect people of all ages, its onset during childhood can be particularly distressing for both children and their parents. The emotional and psychological impact is significant, and early detection, accurate diagnosis, and personalized treatment are critical to managing this condition effectively in children.

This article explores the unique challenges of alopecia areata in children, how it differs from adult cases, the diagnostic hurdles that parents and doctors face, and the best-suited treatment approaches—including emerging natural and Ayurvedic options.

Understanding Alopecia Areata in Children

Alopecia areata in children typically presents before the age of 15 in a significant number of cases. It is characterized by sudden hair loss in small, round patches on the scalp and, in some instances, eyebrows, eyelashes, or body hair. The course of the disease is unpredictable. Some children may experience spontaneous regrowth, while others may face recurring episodes or progression to more extensive forms like alopecia totalis (complete scalp hair loss) or alopecia universalis (total body hair loss).

The exact cause remains unknown, but it is believed to be a combination of genetic predisposition and environmental triggers. Stress, infections, and certain allergens are potential contributors. Since the immune system is still developing in children, autoimmune responses may manifest more abruptly.

Early Signs to Watch For

Recognizing alopecia areata in its early stages can lead to better management and improved outcomes. Parents and caregivers should look out for:

Sudden patchy hair loss: Small round bald spots with smooth, normal-looking skin.

Tingling or itching: Some children may report sensations on the scalp prior to hair loss.

Nail changes: Pitting or ridges in fingernails and toenails can be a related sign.

Regrowth with white or fine hair: New hair may appear white or finer than the surrounding hair.

Loss of eyebrows or eyelashes: Less common but particularly concerning in pediatric cases.

Early intervention can reduce the likelihood of widespread hair loss and improve the child’s self-esteem and emotional health.

Diagnostic Challenges in Children

Diagnosing alopecia areata in children is not always straightforward. Several factors make it more complex:

Overlap with other conditions: Tinea capitis (a fungal infection), trichotillomania (hair-pulling disorder), and nutritional deficiencies can also cause hair loss, leading to potential misdiagnosis.

Emotional sensitivity: Young children may struggle to express symptoms clearly or may feel embarrassed, which can delay clinical visits.

Limited diagnostic tools: A child-friendly, non-invasive diagnosis requires skilled dermatological assessment, sometimes supported by scalp biopsy or dermoscopy.

Psychological evaluation: Stress-induced hair loss may require an understanding of the child’s emotional and mental health, making interdisciplinary diagnosis more effective.

For parents, it is essential to consult a dermatologist with experience in pediatric alopecia and explore all possible causes before initiating treatment.

Tailored Treatment Approaches for Children

Treatment of alopecia areata in children must be safe, gentle, and holistic. Here are some approaches commonly recommended:

1. Topical Therapies

Corticosteroid creams or foams are often the first line of treatment.

Minoxidil may be prescribed to stimulate regrowth, though it is used cautiously in children.

2. Immunotherapy

Applied under medical supervision, this method helps retrain the immune system to tolerate hair follicles again.

3. Light Therapy (Phototherapy)

UV light treatment has shown effectiveness in some pediatric cases with extensive hair loss.

4. Nutritional Support

A diet rich in iron, zinc, biotin, and vitamin D can support hair growth.

Children with autoimmune conditions often benefit from anti-inflammatory diets.

5. Psychological Support

Professional counseling or support groups help children cope with peer pressure, bullying, or self-image issues.

Parents should create a supportive environment, reinforcing the idea that their child's worth is not tied to physical appearance.

6. Ayurvedic Treatments

Increasingly, parents are turning to natural remedies to treat alopecia areata in a gentle and holistic way.

Alopecia Areata Ayurvedic Treatment offers a customized and side-effect-free approach that focuses on restoring immune balance, purifying the blood, and nourishing hair follicles.

Herbal oils, detox therapies (Panchakarma), and diet changes are commonly used in Ayurvedic protocols to support regrowth.

Why Ayurvedic Treatment is Gaining Ground

Modern medicine primarily manages symptoms, while Ayurveda addresses the root cause. Children benefit particularly well from Ayurvedic treatments because:

The approach is non-invasive and gentle.

It considers individual constitution (Prakriti), offering personalized care.

Treatments can be combined with diet, lifestyle, and emotional wellness.

Long-term benefits can be achieved without side effects.

Families seeking Alopecia Areata Ayurvedic Treatment In Kerala often find not only visible improvement in hair regrowth but also better overall immunity and emotional balance.

Choosing the Right Treatment Center

When managing alopecia areata in children, it’s important to choose a treatment facility that combines clinical expertise with holistic care. A reputed Hair Treatment Hospital In Kerala can offer multi-disciplinary approaches including Ayurvedic physicians, dermatologists, nutritionists, and child psychologists working together.

Such integrated care ensures:

Accurate diagnosis through clinical and Ayurvedic assessment.

Age-appropriate and safe treatments.

Emotional and psychological support for both child and family.

Final Thoughts

Alopecia areata in children is a complex condition that impacts physical appearance and emotional well-being. Early detection, accurate diagnosis, and compassionate treatment are key to helping children navigate this challenge confidently. Tailored solutions—including emerging Ayurvedic options—offer a path not only to hair regrowth but to holistic healing.

Parents should remain proactive, informed, and optimistic. With the right care and environment, children with alopecia areata can thrive emotionally and physically, reclaiming their self-esteem and overall health.

[litefacts23]

Can Vitamin B12 Deficiency Be a Sign of Cancer?

Vitamin B12 plays a vital role in keeping your blood cells healthy and supporting brain function. A deficiency in this essential nutrient can cause fatigue, weakness, numbness, and even mood changes. But a question many people ask is: Can vitamin B12 deficiency be a sign of cancer?

Understanding Vitamin B12 Deficiency

Vitamin B12 deficiency occurs when your body doesn’t get enough of this nutrient or can’t absorb it properly. This can happen due to:

Poor diet (especially in vegans and vegetarians)

Malabsorption issues (such as celiac or Crohn's disease)

Lack of intrinsic factor (a protein needed to absorb B12)

Autoimmune conditions like pernicious anemia

Symptoms of B12 deficiency include fatigue, pale skin, shortness of breath, brain fog, tingling in the hands and feet, and balance problems.

How B12 Deficiency Can Be Related to Cancer

While a lack of B12 is not considered a direct sign of cancer, there are a few scenarios where a deficiency might indicate an underlying or developing issue:

1. Stomach or Intestinal Cancer

Cancers that affect the stomach lining or small intestine can interfere with B12 absorption. These include:

Gastric (stomach) cancer

Small intestine cancer

Such cancers may damage the cells that produce intrinsic factor, which is essential for absorbing B12. As a result, B12 deficiency can be an indirect consequence of digestive tract tumors.

2. Pernicious Anemia and Cancer Risk

Pernicious anemia is an autoimmune disease that causes B12 deficiency. Studies show that people with long-term pernicious anemia have a higher risk of developing gastric cancer. This does not mean B12 deficiency causes cancer, but it may indicate a greater likelihood of certain cancers due to underlying autoimmune or inflammatory processes.

3. Cancer Treatments and B12 Deficiency

Chemotherapy and radiation therapy, especially when focused on the abdominal region, can damage the stomach lining or gut, leading to B12 absorption problems. Again, the deficiency is more likely to be a side effect of treatment rather than a symptom of the cancer itself.

When to See a Doctor

If you have a B12 deficiency, it’s important not to panic. Most cases are due to non-cancerous causes like poor nutrition or gastrointestinal conditions. However, you should consult a healthcare professional if you experience:

Severe or prolonged B12 deficiency despite supplementation

Unexplained weight loss

Digestive problems or abdominal pain

Chronic fatigue or neurological issues

Your doctor may recommend further tests to rule out underlying causes, including cancers if necessary.

Final Thoughts

While vitamin B12 deficiency is not commonly a sign of cancer, it can sometimes be associated with cancers that affect nutrient absorption, such as stomach or intestinal cancers. It may also be linked to a higher cancer risk in those with long-term autoimmune conditions like pernicious anemia.

[fuzzycrownking]

Arthritis Therapeutics Market: Growth Driven by Aging Population, Innovation, and Global Healthcare Advancements

The arthritis therapeutics market has seen considerable growth in recent years and is projected to continue expanding steadily. This growth is driven by a confluence of demographic, clinical, technological, and economic factors that are shaping demand for more effective and personalized treatment options. Understanding these market drivers is essential for stakeholders, from pharmaceutical companies to healthcare providers and investors.

1. Rising Global Prevalence of Arthritis

One of the most significant drivers of the arthritis therapeutics market is the increasing prevalence of arthritis worldwide. As populations age, the incidence of osteoarthritis and rheumatoid arthritis continues to rise. Older adults are particularly susceptible to degenerative joint diseases, and with longer life expectancies globally, the number of people living with arthritis is growing. In addition, lifestyle-related factors such as obesity, sedentary behavior, and poor diet contribute to joint degradation and inflammation, accelerating the onset of arthritis in younger age groups. This broadening patient demographic is expanding the demand for various treatment options, from pain relievers to biologic therapies.

2. Technological Advancements in Drug Development

Innovations in biotechnology and pharmaceutical research have significantly improved the development of arthritis therapeutics. Advances in biologics, including monoclonal antibodies and disease-modifying antirheumatic drugs (DMARDs), have transformed the treatment landscape. Biologics can precisely target inflammatory pathways and provide better symptom control than traditional nonsteroidal anti-inflammatory drugs (NSAIDs). Furthermore, the emergence of biosimilars—cheaper, near-identical versions of biologic drugs—has opened up treatment access to a wider population, particularly in cost-sensitive markets.

Pharmaceutical companies are also exploring novel drug delivery methods, such as extended-release formulations, intra-articular injections, and transdermal patches, which enhance patient compliance and therapeutic efficacy. These innovations continue to strengthen the pipeline for arthritis treatment and sustain market momentum.

3. Government Initiatives and Healthcare Infrastructure Expansion

Government support through healthcare programs, reimbursement schemes, and public awareness campaigns is playing a key role in market expansion. In many countries, arthritis is now recognized as a major public health concern, prompting initiatives that improve diagnosis, early intervention, and access to therapy. National health systems in developed economies are increasingly covering advanced therapies, making treatments more accessible to the aging population. Simultaneously, the expansion of healthcare infrastructure in emerging economies is facilitating wider distribution of therapeutics and improved access to care.

4. Increased Awareness and Early Diagnosis

There has been a marked improvement in public awareness of arthritis symptoms and the benefits of early diagnosis. Health campaigns and educational efforts led by patient advocacy groups, healthcare providers, and governments have encouraged individuals to seek medical attention sooner. Earlier diagnosis can slow disease progression and reduce the likelihood of joint damage, increasing the demand for therapeutic intervention at earlier stages. This shift is expanding the patient base for treatment and boosting demand across various stages of the disease.

5. Shift Toward Personalized Medicine

The growing emphasis on personalized medicine is another powerful market driver. Advances in genetic testing and biomarker identification are enabling the development of targeted treatments tailored to individual patient profiles. This is especially critical in rheumatoid arthritis and other autoimmune forms, where treatment response can vary widely. Pharmaceutical companies are increasingly incorporating pharmacogenomic data into clinical trials and therapeutic development, allowing for more effective and safer treatments. Personalized medicine not only enhances patient outcomes but also reduces healthcare costs in the long run by minimizing trial-and-error prescribing.

6. Expanding Geriatric Population

The global demographic trend toward aging is a fundamental driver of the arthritis therapeutics market. Seniors are more likely to suffer from chronic diseases, including arthritis, which leads to increased consumption of medications and regular medical care. As the proportion of the elderly grows, particularly in regions such as North America, Europe, and East Asia, the demand for chronic disease management—including arthritis treatment—rises in tandem. This demand influences pharmaceutical companies to focus R&D efforts on senior-friendly drug formulations and combination therapies tailored for aging bodies.

7. R&D Investment and Strategic Collaborations

The arthritis therapeutics space is witnessing significant investment from both public and private sectors. Leading pharmaceutical firms are allocating substantial resources to arthritis-focused R&D programs, often forming strategic alliances with biotech firms, research institutions, and universities. These collaborations are accelerating the discovery of novel compounds, improving clinical trial design, and facilitating faster regulatory approvals. In turn, this enhances market competitiveness and brings innovative therapies to market more quickly.

Conclusion

The arthritis therapeutics market is being driven by a powerful combination of demographic trends, scientific advancements, and systemic healthcare improvements. With aging populations, technological breakthroughs in biologics and drug delivery, growing awareness, and supportive government policies, the market is poised for continued expansion. Companies that align their strategies with these market drivers—focusing on innovation, accessibility, and patient-centered care—are well-positioned to lead in this evolving and increasingly critical therapeutic area.