#pollution:

[jcmarchi]

Heavy metals are toxic to ovaries, may lead to earlier menopause - Technology Org

New Post has been published on https://thedigitalinsider.com/heavy-metals-are-toxic-to-ovaries-may-lead-to-earlier-menopause-technology-org/

Heavy metals are toxic to ovaries, may lead to earlier menopause - Technology Org

Middle-aged women with elevated levels of heavy metals are more likely to have depleted ovarian function and egg reserves, which may lead to earlier arrival of menopause and its negative health effects, a new University of Michigan study shows.

Focus on cadmium, lead and mercury that are forbidden in european legislation inside electronics.

Researchers reviewed data on hundreds of women approaching menopause and found that the presence of cadmium, mercury, and arsenic in their urine was connected to low levels of anti-Müllerian hormone (AMH). AMH measures ovarian reserve, or the number of eggs available for fertilization or menstruation. Menopause is the time of life when hormone depletion ends monthly menstruation and sets off many changes to women’s health and wellness.

The observed magnitude of associations between heavy metals and AMH was stronger than the association between smoking and AMH, which is a known risk factor for depleted ovarian reserve, according to the study published in The Journal of Clinical Endocrinology & Metabolism.

“Widespread exposure to toxins in heavy metals may have a big impact on health problems linked to earlier aging of the ovaries in middle-aged women, such as hot flashes, bone weakening and osteoporosis, higher chances of heart disease, and cognitive decline,” said study author Sung Kyun Park, associate professor of epidemiology and environmental health sciences at the U-M School of Public Health.

“Our study linked heavy metal exposure to lower levels of anti-Müllerian hormone in middle-aged women. AMH tells us roughly how many eggs are left in a woman’s ovaries. It’s like a biological clock for the ovaries that can hint at health risks in middle age and later in life.”

Using data from the longitudinal Study of Women’s Health Across the Nation, Park and colleagues reviewed 2,252 repeated measurements of AMH in 549 women within 10 years after their final menstrual period. The women in the study were ages 45 to 56 were ethnically diverse: 45% white, 21% Black, 15% Chinese and 19% Japanese.

“Given that heavy metals are widespread in the general population and urinary metal concentrations measured in our study were comparable to the general female population across the United States, the potential adverse effects of heavy metals on ovarian function should be of significant public health concern,” Park said.

Arsenic, cadmium, mercury and lead are commonly found in drinking water, air pollution and some foods, notably seafood and rice. The metals are considered endocrine-disrupting chemicals that can cause infertility, cancers and other diseases.

Prior research offers toxicological evidence that heavy metals may negatively affect reproductive health. Only a few studies have explored associations of cadmium and lead with AMH, reporting that cadmium may alter AMH concentrations in pregnant women and premenopausal women ages 30 to 45. The new study focused on perimenopausal women.

This information may enable researchers to address adverse health outcomes known to be associated with metals and with reproductive hormone changes such as premature menopause, bone loss and osteoporosis, increased risks of cardiovascular disease, cognitive decline and vasomotor symptoms, according to the study authors.

“We see this significant public health concern, which may also have implications for women of all ages,” Park said.

The researchers say their findings require further investigation, particularly in a younger population, to fully understand the role of heavy metals as potential ovarian toxicants that diminish ovarian reserves.

Source: University of Michigan

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[longreads]

How Concerned Citizens Drove a Neo-Nazi Out of Rural Maine

Christopher Pohlhaus planned to build a fascist training compound in the woods of rural Maine. The local journalists, veterans, lumberjacks, and policymakers weren't having it.

Pohlhaus, 37, is a former U.S. marine, an itinerant tattoo artist, and a hardcore white-supremacist influencer. He is loud and hostile, and proud to be both. His voice is pitched surprisingly high, and he has a slight Southern drawl. He has a large body and small bald head; a blue-black tattoo crawls up the right side of his face, from his chin to his forehead. Over the years, Pohlhaus has collected thousands of social media followers, who know him by his nickname: Hammer.

Hammer had been living in Texas for a few years when, in March 2022, he bought the land in Maine. He told his followers that he was going to use it to build a haven, operational center, and training ground for white supremacists.

Check out our excerpt of The Atavist’s latest blockbuster story. 

[389]

PORTO ROCHA

[nanaluvbug]

🧀🥪🌶️🥭 The Ravening War portraits  🧀🥪🌶️🥭

patreon * twitch * shop  

[ID: a series of digitally illustrated portraits showing - top left to bottom right - Bishop Raphaniel Charlock (an old radish man with a big red head and large white eyebrows & a scraggly beard. he wears green and gold robes with symbols of the bulb and he smirks at the viewer) Karna Solara (a skinny young chili pepper woman with wavy green hair, freckled light green skin with red blooms on her cheeks. she wears a chili pepper hood lined with small pepper seeds and stares cagily ahead) Thane Delissandro Katzon (a muscular young beef man with bright pinkish skin with small skin variations to resemble pastrami and dark burgundy hair. he wears a bread headress with a swirl of rye covering his ears and he looks ahead, optimistic and determined) Queen Amangeaux Epicée du Peche (a bright mango woman with orange skin, big red hair adorned with a green laurel, and sparkling green/gold makeup. she wears large gold hoop earrings and a high leafy collar) and Colin Provolone (a scraggly cheese man with waxy yellow skin and dark slicked back hair and patchy dark facial hair. he wears a muted, ratty blue bandana around his neck and raises a scarred brow at the viewer with a smirk) End ID.)

[70sscifiart]

One of my favorites by Paul Lehr, used as a 1971 cover to "Earth Abides," by George R. Stewart. It's also in my upcoming art book!

[taizooo]

もともとは10年ほど前にTumblrにすごくハマっていて。いろんな人をフォローしたらかっこいい写真や色が洪水のように出てきて、もう自分で絵を描かなくて良いじゃん、ってなったんです。それで何年も画像を集めていって、そこで集まった色のイメージやモチーフ、レンズの距離感など画面構成を抽象化して、いまの感覚にアウトプットしています。画像の持つ情報量というものが作品の影響になっていますね。

映画『きみの色』山田尚子監督×はくいきしろい対談。嫉妬し合うふたりが語る、色と光の表現｜Tokyo Art Beat

[layla-keating]

#thistension

XO, KITTY — 1.09 “SNAFU”

[nevver]

No one wants to be here and no one wants to leave, Dave Smith (because)

[foodffs]

Noodles with Lamb Sauce (Laghman, 新疆拌面) Xinjiang laghman features chewy noodles served with a bold and rich lamb and tomato sauce that is bursting with flavor.

Recipe: https://omnivorescookbook.com/recipes/uyghur-style-noodles-with-lamb-sauce

[lesserknownbots]

CJ from Hello World (MSPFA) by phasedsun?

[jcmarchi]

Challenge: Optimization of Petrochemical Assets Using Linear Programming - Technology Org

New Post has been published on https://thedigitalinsider.com/challenge-optimization-of-petrochemical-assets-using-linear-programming-technology-org/

Challenge: Optimization of Petrochemical Assets Using Linear Programming - Technology Org

The goal of this Challenge is to optimize petrochemical assets by using Linear Programming.

We use Linear Programming (LP) software to optimize petrochemical assets at one of our refineries. The software uses certain parameters (prices, feedstock availability, product demands, unit constraints, etc.) to identify the optimal refinery operation and feed-product mix. This optimization also includes predicted time spent producing fuels products and time producing lubricants products.

The impact of air pollution. Image credit: Unsplash

Unfortunately, LP software has certain limitations in solving multiple equations simultaneously. As a result, attempts to optimize complex operations of a modern-day refinery require extended computing time, making the whole process inefficient.

By posting this Challenge, we want to find a “golden middle”: a Linear Programming modelling approach that can deal with multiple modes of operations and yet remain within reasonable execution times and the capacities of the LP platform.

This is a Prize Challenge which requires a written proposal to be submitted and there will be a guaranteed award for at least one submitted solution. By submitting a proposal, the Solver grants the Seeker a right to use any information included in their proposal.

Submissions to this Challenge must be received by 11:59 PM (US Eastern Time) on February 12, 2024.

Source: Wazoku

You can offer your link to a page which is relevant to the topic of this post.

[389]

PORTO ROCHA

[theroyalweekly]

HRH The Princess of Wales in Southport today, on her first engagement since completing chemotherapy. It’s so good to see her!❤️ --

[shitakeo33]

よく「発明は1人でできる。製品化には10人かかる。量産化には100人かかる」とも言われますが、実際に、私はネオジム磁石を1人で発明しました。製品化、量産化については住友特殊金属の仲間たちと一緒に、短期間のうちに成功させました。82年に発明し、83年から生産が始まったのですから、非常に早いです。そしてネオジム磁石は、ハードディスクのＶＣＭ(ボイスコイルモーター)の部品などの電子機器を主な用途として大歓迎を受け、生産量も年々倍増して、2000年には世界で1万トンを超えました。

世界最強「ネオジム磁石はこうして見つけた」（佐川眞人 氏 ／ インターメタリックス株式会社 代表取締役社長） | Science Portal - 科学技術の最新情報サイト「サイエンスポータル」

[kithtaehyung]

AGUST D : DAECHWITA (大吹打) & HAEGEUM (解禁)  ⤷ movie posters | ig ; twt (click for hi-res)

[magicshop]

You, who gave me their hand when I fell, now I'll hold it for you.