#christianity is a cancer

[disgruntledexplainer]

There is a 2-year-old kid at my church who just got leukemia. Please pray for him.

[carby]

I just sent the text that ended my relationship with my father. New year, freer me.

[post-punk-author-anthony-day]

Goth -  Death in June, March Violets, Clan of Xymox, Christian Death, Southern Death Cult, Sisters of Mercy, Drab Majesty, Tropic of Cancer, 13th Chime, And Also the Trees, 

No Wave (Ice age, Sonic Youth) 

Darkwave - IAMTheShadow, this cold night, Tropic of Cancer, Nation of Language, Ritual Howls, A Projection, Topographies, Siglo XX, Bolshoi, Lust for Youth, VR Sex, A place to bury strangers 

[mostlysignssomeportents]

Uncle Sam paid to develop a cancer drug and now one guy will get to charge whatever he wants for it

Today (Oct 19), I'm in Charleston, WV to give the 41st annual McCreight Lecture in the Humanities. Tomorrow (Oct 20), I'm at Charleston's Taylor Books from 12h-14h.

The argument for pharma patents: making new medicines is expensive, and medicines are how we save ourselves from cancer and other diseases. Therefore, we will award government-backed monopolies – patents – to pharma companies so they will have an incentive to invest their shareholders' capital in research.

There's plenty wrong with this argument. For one thing, pharma companies use their monopoly winnings to sell drugs, not invent drugs. For every dollar pharma spends on research, it spends three dollars on marketing:

https://www.bu.edu/sph/files/2015/05/Pharmaceutical-Marketing-and-Research-Spending-APHA-21-Oct-01.pdf

And that "R&D" isn't what you're thinking of, either. Most R&D spending goes to "evergreening" – coming up with minor variations on existing drugs in a bid to extend those patents for years or decades:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680578/

Evergreening got a lot of attention recently when John Green rained down righteous fire upon Johnson & Johnson for their sneaky tricks to prevent poor people from accessing affordable TB meds, prompting this excellent explainer from the Arm and A Leg Podcast:

https://armandalegshow.com/episode/john-green-part-1/

Another thing those monopoly profits are useful for: "pay for delay," where pharma companies bribe generic manufacturers not to make cheap versions of drugs whose patents have expired. Sure, it's illegal, but that doesn't stop 'em:

https://www.ftc.gov/news-events/topics/competition-enforcement/pay-delay

But it's their money, right? If they want to spend it on bribes or evergreening or marketing, at least some of that money is going into drugs that'll keep you and the people you love from enduring unimaginable pain or dying slowly and hard. Surely that warrants a patent.

Let's say it does. But what about when a pharma company gets a patent on a life-saving drug that the public paid to develop, test and refine? Publicly funded work is presumptively in the public domain, from NASA R&D to the photos that park rangers shoot of our national parks. The public pays to produce this work, so it should belong to the public, right?

That was the deal – until Congress passed the Bayh-Dole Act in 1980. Under Bayh-Dole, government-funded inventions are given away – to for-profit corporations, who get to charge us whatever they want to access the things we paid to make. The basis for this is a racist hoax called "The Tragedy Of the Commons," written by the eugenicist white supremacist Garrett Hardin and published by Science in 1968:

https://memex.craphound.com/2019/10/01/the-tragedy-of-the-commons-how-ecofascism-was-smuggled-into-mainstream-thought/

Hardin invented an imaginary history in which "commons" – things owned and shared by a community – are inevitably overrun by selfish assholes, a fact that prompts nice people to also overrun these commons, so as to get some value out of them before they are gobbled up by people who read Garrett Hardin essays.

Hardin asserted this as a historical fact, but he cited no instances in which it happened. But when the Nobel-winning Elinor Ostrom actually went and looked at how commons are managed, she found that they are robust and stable over long time periods, and are a supremely efficient way of managing resources:

https://pluralistic.net/2023/05/04/analytical-democratic-theory/#epistocratic-delusions

The reason Hardin invented an imaginary history of tragic commons was to justify enclosure: moving things that the public owned and used freely into private ownership. Or, to put it more bluntly, Hardin invented a pseudoscientific justification for giving away parks, roads and schools to rich people and letting them charge us to use them.

To arrive at this fantasy, Hardin deployed one of the most important analytical tools of modern economics: introspection. As Ely Devons put it: "If economists wished to study the horse, they wouldn’t go and look at horses. They’d sit in their studies and say to themselves, ‘What would I do if I were a horse?’"

https://pluralistic.net/2022/10/27/economism/#what-would-i-do-if-i-were-a-horse

Hardin's hoax swept from the fringes to the center and became received wisdom – so much so that by 1980, Senators Birch Bayh and Bob Dole were able to pass a law that gave away publicly funded medicine to private firms, because otherwise these inventions would be "overgrazed" by greedy people, denying the public access to livesaving drugs.

On September 21, the NIH quietly published an announcement of one of these pharmaceutical transfers, buried in a list of 31 patent assignments in the Federal Register:

https://public-inspection.federalregister.gov/2023-20487.pdf

The transfer in question is a patent for using T-cell receptors (TCRs) to treat solid tumors from HPV, one of the only patents for treating solid tumors with TCRs. The beneficiary of this transfer is Scarlet TCR, a Delaware company with no website or SEC filings and ownership shrouded in mystery:

https://www.bizapedia.com/de/scarlet-tcr-inc.html

One person who pays attention to this sort of thing is James Love, co-founder of Knowledge Ecology International, a nonprofit that has worked for decades for access to medicines. Love sleuthed out at least one person behind Scarlet TCR: Christian Hinrichs, a researcher at Rutgers who used to work at the NIH's National Cancer Institute:

https://www.nih.gov/research-training/lasker-clinical-research-scholars/tenured-former-scholars

Love presumes Hinrichs is the owner of Scarlet TCR, but neither the NIH nor Scarlet TCR nor Hinrichs will confirm it. Hinrichs was one of the publicly-funded researchers who worked on the new TCR therapy, for which he received a salary.

This new drug was paid for out of the public purse. The basic R&D – salaries for Hinrichs and his collaborators, as well as funding for their facilities – came out of NIH grants. So did the funding for the initial Phase I trial, and the ongoing large Phase II trial.

As David Dayen writes in The American Prospect, the proposed patent transfer will make Hinrichs a very wealthy man (Love calls it "generational wealth"):

https://prospect.org/health/2023-10-18-nih-how-to-become-billionaire-program/

This wealth will come by charging us – the public – to access a drug that we paid to produce. The public took all the risks to develop this drug, and Hinrichs stands to become a billionaire by reaping the rewards – rewards that will come by extracting fortunes from terrified people who don't want to die from tumors that are eating them alive.

The transfer of this patent is indefensible. The government isn't even waiting until the Phase II trials are complete to hand over our commonly owned science.

But there's still time. The NIH is about to get a new director, Monica Bertagnolli – Hinrichs's former boss – who will need to go before the Senate Health, Education, Labor and Pensions Committee for confirmation. Love is hoping that the confirmation hearing will present an opportunity to question Bertagnolli about the transfer – specifically, why the drug isn't being nonexclusively licensed to lots of drug companies who will have to compete to sell the cheapest possible version.

If you'd like an essay-formatted version of this post to read or share, here's a link to it on pluralistic.net, my surveillance-free, ad-free, tracker-free blog:

https://pluralistic.net/2023/10/19/solid-tumors/#t-cell-receptors

My next novel is The Lost Cause, a hopeful novel of the climate emergency. Amazon won't sell the audiobook, so I made my own and I'm pre-selling it on Kickstarter!

[religious-extremist]

Prayer Paraphernalia

[herdreamywasteland]

prayer request

If y'all could pray for my Aunt Victoria, I would be so grateful.

She has stage 4 ovarian cancer, and it's a very rare type with almost no research on it.

Even if you aren't religious, please just keep her in your thoughts or say a Hail Mary for her.

Thank you, have a blessed day <3

[theoneobserving]

The priest at church yesterday said a guy he knew was recently diagnosed with cancer and the doctor doesn’t expect him to make it to Christmas. The guy said God had been so good to him and the priest said if God was so good to him then why wouldn’t he want to bring him home? The priest said it was a great blessing because so many people die without getting a chance to say goodbye but he knows and has that chance

Lord, please help us see your blessings in literally everything

[thomastanker02]

Prayer Request, Cancer Diagnosis

[eretzyisrael]

Good News From Israel

Israel's Good News Newsletter to 3rd Nov 24

In the 3rd Nov 24 edition of Israel’s good news, the highlights include:

Christian Zionists donate dozens of ambulances and emergency vehicles.

Israeli researchers discover a breakthrough mechanism for eradicating cancer.

Israeli volunteers rush to help Polish flood victims.

An Israeli startup has a unique method for detecting hostile drones.

Three new Israeli innovations to clean up our environment.

The 100th anniversary of the birth of Ephraim Kishon - Israel’s greatest satirist.

The festival of Simchat Torah was celebrated in Israel with joy and dignity.

Read More: Good News From Israel

Israel's seasonal rains are beginning, just after Jews finish reading the Torah portion about Noah and the Flood.  Israelis are currently helping flood victims in Poland, although Spain may have to wait a little longer for Israeli aid. Israel's enemies called their Oct 7 invasion a "Flood", and Israel is successfully responding to that desecration of its holy Simchat Torah festival. Finally, whereas Noah's Flood created a new, clean world, Israeli innovations are repairing this world by purifying the environment, desalinating sea-water, and generating clean energy. Israelis are working hard to eliminate many of the world's other major problems too.

The photo is of the sea from Israel's shoreline. It is probably similar to the harmonious scene that Noah experienced when the rains finally stopped those many years ago.

[virgocurator]

Medieval Zodiac Signs (April-June)

“Très Riches Heures du duc de Berry” or The Very Rich Hours of the Duke of Berry is the most famous example of an illuminated manuscript in the Gothic style because of its near perfect preservation. The book contains a collection of prayers for each month of the year. As seen in the top blue crescents, there are corresponding zodiac sign symbols.

April Slide 1: (Aries and Taurus)

May Slide 2: (Taurus and Gemini)

June Slide 3: (Gemini and Cancer)

[beheworthy]

+

(from Thor The Mighty Avenger #8​)

[nohumancandrown]

𓉸ྀི 𝕶𝖔𝖒𝖒𝖚𝖓𝖎𝖙𝖞 𝕱𝕶𓉸ྀི

[k-i-l-l-e-r-b-e-e-6-9]

Decapitated - Last Supper

[herdreamywasteland]

Prayer request

Please pray for my neighbor, Susan Fiorino, as she died in her sleep sometime this morning, due to stomach cancer. Please also pray for her husband, Billy, as he's really struggling from this.

They were married for almost 50 years. I used to clean their house and help Susan cook for Thanksgiving, and they were really good people. Please pray for them both.

I'm going over to Billy's house tomorrow, so if you have any kind words or comforts, let me know, and I'll pass them on.

God bless you all.