#catapres
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sometimes i am the queen of emotional regulation and sometimes its like... i have to return some video tapes
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hi sasha!!! :D Hows it going?
pretty good actually! i should probably sleep, its 2:30am but im out of catapres :/ so i just have to wait until im so exhausted i cant keep my eyes open anymore. so like 6am probably
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Hanazaki’s medication :: [ Source ]
fluphenazine & pimozide
( not a double dose; these are the drugs he can take; if he runs out of the drugs given to him at his local hospital. Fluphenazine; is his prescript-ed medication, however. )
What it does: Lessens / Blocks dopamine in the system.
What does it do for Hanazaki: Helps him control his more volatile tics.
Side effects: Weight Gain & Involuntary repetitive movements.
adhd medication - concerta
What it does: Aids Methylphenidate in the body to help increase attention and concentration.
What does it do for Hanazaki: Allows him to sit in his university classes without missing a thing due to his tics taking over. He doesn’t use this tablet every day but it at least once a week to help himself out during stressful times.
Side effects: Some ADHD medication can exacerbate his tics. So far, this one hasn’t made them any more worse than they are.
antidepressant - sarafem
What it does: Help control symptoms of sadness, anxiety and OCD
What it does for Hanazaki: Settles him down very fast; though he doesn’t like these meds since he feels very - hollow - after taking them. However, it is one of the best medications to give him when his system is near overdrive in outside stimulation and his tics are in control from other medication. These are the days when Hanazaki is very low; in his head and making things mentally worse for himself. Blaming himself for things in the past.
Hanazaki used to have; clonifine ( catapres ) though it usually treats high blood pressure; it also helps him have impulse control; however, the drug made him exhausted to the point he’d be asleep in a matter of hours after taking the pill. His parents and doctor deemed it an unnecessary drug to take; so he moved Ieji off the drug within the last few months.
Even though Hanazaki is on medication; it is his last resort. Having grown with those drugs are a child and now an adult; he has seen a huge difference in his symptoms. It was in a recent discussion with his GP and Therapist that he quits the medication. Feeling like he is becoming too dependent on them and out of fearing the worst; ‘of not ever being able to give them up to feel normal in society’, his GP and Therapist are currently looking into the possibility.
The worst that Hanazaki could go through is; withdraw symptoms from the medication he takes the other, Hanazaki’s tics come back worse. However, knowing of Hanazaki’s lifestyle, family support and current goal in life; they believe Hanazaki has a good chance of becoming medication independent; in terms that Hanazaki knows what to take when he needs to take it and not; take it when the clock strikes a certain hour.
Hanazaki will be reviewed again in a mouth; before he will take on the trial of not having to take medication for his Tourette. A trial period of two months; will be given to him, once his GP and Therapist sort things out on their end.
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Non-stimulant medications: Non-stimulants: atomoxetine (Strattera), clonidine (Catapres), clonidine XR (Kapvay), guanfacine (Tenex), Guanfacine XR (Intuniv)
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Medications for Tourettes Syndrome
*This is not intended to be taken as medical advice. This is purely for educational purposes*
Goal of pharmaceutical treatment of TS
The goal of using medications in the treatment of Tourettes syndrome is not to completely remove tics but to help them become more managable along with any comorbid disorders.
Currently approved drugs for the treatment of TS
Neuroleptics: Haloperidol (Haldol), Pimozide (Orap), Aripiprazole (Abilify). Neuroleptics act to antagonize dopamine, through the blockade of type 2 dopamine receptors. In general, the higher the potency of dopamine blockade, the more effective a drug is in ameliorating tics.
Drugs used off-label for the treatment of TS
Atypical Antipsychotics: Risperidone (Risperdal), Clozapine, Olanzapine (Zyprexa), Quetiapine (Seroquel). Atypical antipsychotics are more selective dopamine receptor D2 blockers, although they can also affect serotonin. These drugs include risperidone, clozapine, olanzapine, quetiapine and the partial agonist aripiprazole. Atypical antipsychotics may be considered a safer treatment for tics due to the reduced risk of developing acute or subacute side effects. Risperidone may also treat comorbid aggression and obsessive-compulsive symptoms, and Olanzapine may help with morbid ADHD and aggression.
Experimental pharmalogical agents in the treatment of TS
Benzamides: Sulpiride, Tiapride; may also help treat echophenomena, aggression, tension, and obsessive-compulsive comorbidities.
Tetrabenazine: acts as dopamine antagonist, by reducing the presynaptic storage of monoamines and blocking postsynaptic DA receptors.
Alpha adrenergic agonists: Clonidine (Catapres), Guanfacine. These drugs may also help with comorbid oppositional defience, aggression, and obessive-compulsive symptoms.
Benzodiazepines: Clonazepam (Klonopin); addictive and generally best for transient use.
Anticonvulsants: Topiramate (Topamax), Levetiracetam (Keppra); better tolerated than neurleptics but conflicting evidence efficacy.
Dopamine Agonists: Pergolide (Permax), Apomorphine, Buspirone (Buspar), Ropinirole (Requip); typically medications that are used in the treatment of Parkinsonism, low doses may also treat tics.
Cannabinoids: THC in particular may also help with comorbid self-injurious behaviours, obsessive-compulsive symptoms, and ADHD.
*This is not an exhaustive list*
Sources: (x) (x)
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Tranquilizers, also known as anxiolytics or psychotropic drugs, are medications that are used to treat anxiety, insomnia, and other mental health disorders. In the emergency department (ED), tranquilizers are often used to manage agitated or distressed patients, or to sedate patients before procedures.
There are several different types of tranquilizers that are commonly used in the ED, each with its own unique set of characteristics and potential side effects.
• Benzodiazepines
Benzodiazepines are a class of tranquilizers that are widely used in the ED due to their fast-acting sedative effects and low risk of overdose. They work by enhancing the activity of a neurotransmitter called GABA, which slows down the activity of the brain and central nervous system.
Examples of benzodiazepines include lorazepam (Ativan), diazepam (Valium), and midazolam (Versed). These medications are typically given intravenously (IV) or intramuscularly (IM) in the ED and can be used to treat anxiety, insomnia, and alcohol withdrawal.
• Antipsychotics
Antipsychotics, also known as neuroleptics or major tranquilizers, are a class of medications that are used to treat psychosis, schizophrenia, and other mental health disorders. They work by blocking the action of dopamine, a neurotransmitter that is involved in the regulation of mood and behavior.
Examples of antipsychotics include haloperidol (Haldol), olanzapine (Zyprexa), and quetiapine (Seroquel). These medications are typically given orally or by injection in the ED and can be used to treat agitation, psychosis, and delirium.
• Beta blockers
Beta blockers are a class of medications that are commonly used to treat hypertension, angina, and other cardiovascular conditions. They work by blocking the action of the hormone adrenaline, which can help to reduce anxiety and heart rate.
Examples of beta blockers include propranolol (Inderal) and metoprolol (Lopressor). These medications are typically given orally or by injection in the ED and can be used to treat anxiety, hypertension, and tachycardia.
• Sedative-hypnotics
Sedative-hypnotics are a class of medications that are used to induce sleep or sedation. They work by slowing down the activity of the brain and central nervous system.
Examples of sedative-hypnotics include lorazepam (Ativan), zolpidem (Ambien), and eszopiclone (Lunesta). These medications are typically given orally or intravenously in the ED and can be used to treat insomnia and anxiety.
• Alpha-2 agonists
Alpha-2 agonists are a class of medications that are used to sedate patients and reduce anxiety. They work by activating alpha-2 receptors in the brain, which can help to reduce the activity of the sympathetic nervous system and lower blood pressure.
Examples of alpha-2 agonists include clonidine (Catapres) and dexmedetomidine (Precedex). These medications are typically given intravenously or intramuscularly in the ED and can be used to treat agitation and hypertension.
• Barbiturates
Barbiturates are a class of medications that are used to induce sleep or sedation. They work by enhancing the activity of GABA, a neurotransmitter that slows down the activity of the brain and central nervous system.
Examples of barbiturates include pentobarbital (Nembutal) and secobarbital (Seconal). These medications are typically given intravenously or intramuscularly in the ED and can be used to treat severe anxiety or to induce coma in cases of life-threatening conditions such as intracranial pressure or status epilepticus.
It's important to note that all tranquilizers have the potential for side effects and should be used with caution. Common side effects of tranquilizers include drowsiness, dizziness, dry mouth, and constipation. In rare cases, tranquilizers can also cause more serious side effects such as respiratory depression, hypotension, and paradoxical reactions (e.g., agitation or excitement instead of sedation).
In conclusion, tranquilizers are a valuable tool in the management of agitated or distressed patients in the ED. However, it's important for healthcare providers to carefully consider the risks and benefits of these medications and to use them appropriately to minimize the risk of side effects.
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ahahahahahahahahaha pota!! buti tumigil na ko sa pag gamit neto! so far, di pa naman na resetahan ng catapres :D
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Menopause Treatment: During the Alteration of Life
Menopause takes place to ladies who are within their middle ages. It is the permanent end of monthly periods and fertility, identified as occurring 12 months after your last menstrual period. As a woman ages, the function of ovaries and the production of certain growth hormones progressively decline. Ordinarily, women menstruation ends at the age of 50. However, there are several menstrual changes which include shortening of cycle length, skipped menstrual periods, and even infrequent heavy periods which might be noticed a few years before the start of menopause.
Exactly What Are Menopause Indicators And Symptoms?
Signs and symptoms of menopause typically are not easily recognized before condition is clinically diagnosed. Especially as it occurs differently for each woman. Even though some ladies who sail through the transition easily, there are still many others who experience multiple internal and external indicators and symptoms. Some of the common menopausal indicators and symptoms are irregular menstrual bleeding, hot flashes, night sweats, vaginal dryness, moodiness, sleep irregularities, excess weight around the waist, baldness and loss of Menopause hot flashes breast fullness.
Should I Select Symptomatic Treatment Even When My Menopause Is Normal?
Menopause isn't a medical illness, but an all natural biological process. Sometimes even when it occurs naturally, the internal and external indications of menopause can be stressful. Despite of it being a natural process, you shouldn't hesitate to have menopause treatment if you're already suffering from severe symptoms. There are hundreds of menopause treatments in the market and you can easily find the right one for you.
Some Of The Menopause Treatments Options:
The commonly endorsed treatment alternative, hormone replacement therapy (HRT) is used to supplement one's body with estrogen (estrogen therapy) or a combination of estrogen and progesterone (combination therapy). It is actually effective menopause treatment but has its associated health risks.
Low-dose antidepressants especially selective serotonin reuptake inhibitors (SSRIs) have been proved to diminish menopausal flashes. Another drug that's been shown to reduce menopausal flashes is Gabapentin (Neurontin) which is often used to treat seizures not to mention Clonidine (Catapres) that treats blood pressure levels. Bisphosphonates and vaginal estrogen provides estrogen while selective estrogen receptor modulators (SERMs) just like raloxifene (Evista) mimics estrogen's beneficial effects.
Additionally, there are complementary and alternative treatments for menopause such as dietary plus herbs, acupuncture, chiropractic and therapeutic massage, biofeedback, homeopathy, phytoestrogens, vitamin E, and black cohosh. Whatever the case, please do not forget to consult with your physician for alternate medicine as they may interfere or connect to other medications that you may be taking.
How Must I Control My Menopausal Condition?
Taking care of menopause includes a holistic approach to include lifestyle and even dietary aspects, as well as specific treatment alternatives. Take proper diet and enjoy your life. Menopause is nothing to be embarrassed about. Be optimistic and even you will be capable of managing it pretty fine.
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hey isn’t it like five am now??? Sleep!!! Please :)
i took some catapres an hour ago but it still hasn’t kicked in for some reason. i prommy i’ll take some more 💖
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Clonidine (Catapres) is a well-known centrally acting alpha-agonist hypotensive drug that lowers blood pressure by slowing the heart rate or expanding veins.
#clonidine#catapres#attentiondeficithyperactivitydisorder#adhd#antihypertensive#hypertension#tourettesyndrome#mentalhealth#mentalwellness#depression#anxiety
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Clonidine Hydrochloride
Brand Names: Catapres, Nexiclon XR, Kapvay
Generic Available
Common Dosage Forms:
Tablets: 0.1 mg, 0.2 mg, and 0.3 mg.
Tablets, extended-release (Nexiclon XR): 0.17 mg.
Tablets, extended-release (Kapvay): ).1 mg and 0.2 mg.
Transdermal extended-release patches: TTS-1: 0.1 mg/24 hours (2.5 mg/system), TTS-2: 0.2 mg/24 hours (5.0 mg/system), TT-3: 0.3 mg/24 hours (7.5/system).
FDA Indications/Dosages:
For the treatment of hypertension: Oral: Start wit 0.1 mg twice a day. Increase dosage by increments of 0.1 to 0.2 mg per day until desired response is achieved. Normal dosage range is 0.1 to 0.3 mg given twice a day. Extended-release tablets may be given once a day. Transdermal: Apply to a hairless, unbroken area on the upper arm or torso once every 7 days. Start with the 0.1 mg system and increase as needed up to two of the 0.3 systems every 7 days. Change application sites with each new system (weekly).
Treatment of attention deficit hyperactivity disorder (Kapvay): 0.1 to 0.2 mg twice a day. Start with 0.1 mg at bedtime and taper to effective dose.
Pharmacology/Pharmacokinetics: Clonidine stimulates central alpha-adrenergic receptors resulting in inhibition of bulbar sympathetic cardio-accelerator and sympathetic vasoconstrictor centers. This results in reduced sympathetic outflow from the CNS and a decrease in peripheral resistance, renal vascular resistance, heart rate, and blood pressure. Renal blood flow and glomerular filtration rate remain virtually unchanged. Peak plasma levels are reached in 3-5 hours after an oral dose with a half-life of 12-16 hours. Excretion occurs in the urine as unchanged drug and as metabolites.
Drug Interactions: Blood pressure control may be decreased when used with tricyclic antidepressants. Dangerous increases in blood pressure have occurred when used with beta-adrenergic blockers and when either drug is discontinued.
Contraindications/Precautions: Use with caution in patients with severe coronary insufficiency, recent myocardial infarction, cerebrovascular disease, and in patients with chronic renal failure. Sudden cessation of therapy may produce severe hypertension. Pregnancy Category C.
Adverse Effects: Dry mouth, dry eyes, drowsiness, dizziness, headache, fatigue, edema, constipation, and impotence.
Patient Consultation:
May be taken with food or milk if GI upset occurs.
Do not discontinue therapy without first consulting physician.
May cause drowsiness. Use with caution while operating machinery or when mental alertness is required.
Avoid nonprescription products containing decongestants or sodium salts unless recommended by a pharmacist or physician.
Change transdermal skin sites with each application of Catapres-TTS systems.
Store in a cool, dry place away from sunlight and children.
If a dose is missed, take it as soon as possible. If it closer to the time of your next dose than the dose you missed, skip the missed dose and return to your dosing schedule. Do not double doses.
Contact a physician if the above side effects are severe or persistent.
#sigler drug cards#36th edition#clonidine hydrochloride#catapres#nexiclon xr#kapvay#antihypertensive#adhd agent#drug facts
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tbh i feel like having not enough alcohol is almost worse than no alcohol at all
#i only had like 2 shots left#and it's vodka not everclear#had 6 melatonin but no benadryl so i'm not gonna get my hopes up abt sleeping tn#no catapres either#catapres nd everclear knock me right the fuck out when i mix em but i don't have either#nd to add insult to injury the only reason i'm even drinking is bc i emptied my goddamn cart on friday#that shit didn't even last me a fuckinh week nd im legit gonna commit unalive over it i stg#gonna see if i have any more vodka bc this shit isn't enough
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#actually in a thrilling couple of minutes of reading studies#outcomes for Lamictal aren't too bad? in that you wouldn't pop someone on it during#but for ppl already on it ya just gotta be careful immediately postpartum because levels rocket#hmmmm.#citalopram seems to be slightly riskier tho sooo#& catapres is a no-go so that sucks
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Writing characters with Tourette syndrome
By Writerthreads on Instagram
Disclaimer: I do not have Tourette’s so this post is based on Mayo Clinic’s article on this syndrome.
What is Tourette syndrome?
Tourette syndrome is a disorder that involves repetitive movements or unwanted sounds (tics) that can't be easily controlled. Tics typically show up between ages 2 and 15, showing up the most at the age of 6. Males are more likely to develop Tourette syndrome.
The are no cures to Tourette syndrome, but there are treatments. Many people with Tourette syndrome don't need treatment when symptoms aren't troublesome. Tics often lessen or become controlled after the teen years.
Symptoms
Tics can range from mild to severe. Severe symptoms might significantly interfere with communication, daily functioning and quality of life.
Tics are classified as simple or complex.
Simple: sudden, brief and repetitive, involving few muscle groups
Complex: coordinated patterns of movement involving several muscle groups
In addition, tics can:
Vary in type, frequency and severity
Worsen if the character is ill, stressed, anxious, tired or excited
Occur during sleep
Change over time
Worsen in the early teenage years and improve during the transition into adulthood
Characters experience an uncomfortable bodily sensation (premonitory urge) such as an itch, a tingle or tension. Expression of the tic brings relief. With great effort, some people with Tourette syndrome can temporarily stop or hold back a tic.
Causes
The exact cause of Tourette syndrome isn't known. It's a complex disorder likely caused by a combination of inherited and environmental factors.
Risk factors
Risk factors for Tourette syndrome include:
Family history. Having a family history of Tourette syndrome or other tic disorders might increase the risk of developing Tourette syndrome.
Sex. Males are about three to four times more likely than females to develop Tourette syndrome.
Complications
People with Tourette syndrome often lead healthy, active lives. However, Tourette syndrome frequently involves behavioral and social challenges that can harm your self-image.
Conditions often associated with Tourette syndrome include:
ADHD
OCD
Autism spectrum disorder
Learning disabilities
Sleep disorders
Depression
Anxiety disorders
Pain related to tics, especially headaches
Anger-management problems
Treatment
MEDICATION
Medication that reduces or blocks dopamine, eg. Fluphenazine, haloperidol (Haldol), risperidone (Risperdal) and pimozide (Orap)
Botox injections can relieve a simple or vocal tic
ADHD medications
Central adrenergic inhibitors, eg. clonidine (Catapres, Kapvay) and guanfacine (Intuniv) (all might cause sleepiness)
Antidepressants
Antiseizure medications
THERAPY
Behaviour therapy
Psychotherapy
Deep brain stimulation (DBS): For severe tics that don't respond to other treatment (still in early research stages
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Doble Problema: El Hipotiroidismo y La Menopausia
Como mujeres, no solemos hablar de los cambios hormonales que atravesamos durante nuestra vida como, el comienzo o el final de la fertilidad y los cambios dentro de nuestro cuerpo y nuestros cambios emocionales y mentales durante estos eventos. El final de la fertilidad o la menopausia, puede ser un momento difícil emocionalmente y para colmo también debemos lidiar con los síntomas físicos.
Sin embargo, es posible que tampoco sepamos que 1 de cada 8 mujeres también desarrollará una enfermedad de la tiroides en su vida, y será diagnosticada alrededor de la edad de 45 a 55, justo en el momento de la menopausia. Los síntomas que a menudo se atribuyen a la menopausia también pueden ser síntomas de hipotiroidismo, una enfermedad de la glándula tiroides. No existe ninguna indicación o estudio que muestre una conexión entre las mujeres que entran en la menopausia y que esto tenga algún efecto sobre la tiroides.
Desafortunadamente, las encuestas realizadas por la Asociación Estadounidense de Endocrinólogos Clínicos (AACE) informan que solo una de cada cuatro mujeres que hablan con su médico sobre la posibilidad de la menopausia se someterán a pruebas para detectar enfermedades de la tiroides.
La glándula tiroides
La glándula tiroides es una glándula rosada con forma de mariposa que se encuentra en la parte inferior de tu cuello. La glándula tiroides es responsable de mantener el corazón latiendo, el metabolismo, el sistema reproductivo y la temperatura corporal, entre otras funciones corporales, funcionando correctamente. En otras palabras, la glándula tiroides es responsable de mantener tu cuerpo en la mejor salud posible. Cuando tu glándula tiroides no funciona correctamente, tu cuerpo no funcionará correctamente y te sentirás mal.
Aunque se debe hablar de la menopausia, el riesgo de hipotiroidismo aumenta a medida que envejecemos y también se debe hablar de él, especialmente porque algunos de los síntomas tanto de la menopausia como del hipotiroidismo son los mismos. Si ya has hablado con tu médico sobre la menopausia y está tratando los síntomas de la menopausia s��lo para descubrir que los síntomas aún persisten, debes pedirle a tu médico que analice tus niveles de hormona estimulante de la tiroides (TSH).
Las etapas de la menopausia
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El período de la perimenopausia: esta fase tiene síntomas en común con el hipotiroidismo*. Esto ha llevado a los investigadores a creer que puede haber una conexión entre la perimenopausia y la función tiroidea. A medida que los ovarios envejecen, tienden a producir niveles impredecibles de progesterona y estrógeno. Esto confunde al cuerpo y puede causar los siguientes síntomas / problemas:
Sequedad vaginal
Sensibilidad en los senos
Sudores nocturnos
Fatiga *
Dificultad para dormir *
Olvido o niebla mental *
Irritabilidad, cambios de humor *
Sofocos
Periodos erráticos *
El equilibrio hormonal de todo el cuerpo se vuelve impredecible y sofocado, incluyendo el nivel del TSH y las hormonas tiroideas. La transición a la menopausia es impredecible y conduce a niveles irregulares de estrógeno que pueden afectar la función tiroidea. Algunos días puede tener niveles más bajos o más altos de estrógeno, lo que afectará la forma en que funciona la tiroides.
Menopausia: la fase de la menopausia también tiene síntomas en común con el hipotiroidismo*. La menopausia generalmente comienza en mujeres alrededor de las edades de 40 a 58 con la edad promedio de inicio de 51. Algunas mujeres no tendrán ningún problema con los síntomas de la menopausia, mientras que otras pueden experimentar algunos de los siguientes:
Pérdida de plenitud de los senos
Cabello debilitado y piel seca *
Escalofríos
Sofocos
Problemas para dormir*
Mal humor*
Irritabilidad*
Dolor durante el sexo
Depresión*
Aumento de peso*
Posmenopausia: la fase de posmenopausia comienza después de la marca de 1 año de su último período. Durante este tiempo, muchos de los síntomas de la menopausia deberían desaparecer para la mayoría de las mujeres. Pero debido a los niveles más bajos de estrógeno, las mujeres posmenopáusicas tienen un mayor riesgo de problemas de salud como osteoporosis, enfermedades cardíacas y cambios en la vagina y la vejiga.
La transición menopáusica
La transición ocurre alrededor de doce meses después del último período de la mujer. Los años previos a ese punto en el que las mujeres pueden tener cambios en sus ciclos mensuales se denominan transición menopáusica o perimenopausia. Las mujeres pueden comenzar a experimentar cambios alrededor de las edades de 45 a 55 y generalmente duran 7 años, pero pueden durar hasta 14 años. Otras razones por las que puede experimentar la menopausia son una histerectomía o la eliminación quirúrgica de los ovarios o el útero. Esto hará que experimenten la menopausia de inmediato.
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Tu cuerpo cambia
Tus ovarios: durante este período de tiempo, la producción de estrógeno y progesterona en los ovarios aumentará y disminuirá.
Tus huesos: te vuelves más vulnerable a las fracturas a medida que tus huesos se vuelven menos densos.
Tus niveles de energía cambian, lo que te hace sentir fatigada y cansada la mayor parte del tiempo e irritable, incapaz de dormir o dormir más.
Tus células grasas cambian y aumentas de peso con más facilidad, necesitando esforzarte más para perder peso o notas que, aunque no hayas cambiado la forma en que comes, estás aumentando de peso.
La Sociedad Norteamericana de Menopausia (NAMS) ha descubierto que las mujeres que están en la edad de la menopausia pueden experimentar problemas idénticos de hipotiroidismo, por lo que es importante hacerse las pruebas necesarias para ver si sufren de ello también.
Los síntomas que comparten el hipotiroidismo y la menopausia
Cuando llegas a la transición de la menopausia, es fácil confundir los síntomas de la menopausia y el hipotiroidismo, especialmente si ya estás lidiando con hipotiroidismo, ya que comparten problemas idénticos. Los síntomas asociados con ambos son:
Cambios con tu período
Problemas para dormir
Fatiga
Irritabilidad
Niebla del cerebro
Aumento de peso
Pérdida de cabello
Piel seca
Manejo tanto del hipotiroidismo como de la menopausia
El hipotiroidismo puede hacer que la menopausia sea mucho más difícil, por lo que es importante tratar tu hipotiroidismo durante la menopausia, especialmente porque la menopausia no es una condición que dure una semana o dos, puede durar de 7 a 14 años. Cuando el hipotiroidismo no se trata, corres el riesgo de desarrollar otros problemas, como un ataque cardíaco o un derrame cerebral, y presión arterial alta, que tambien pueden provocar otras complicaciones cardíacas. Los trastornos de la tiroides en las mujeres a menudo se diagnostican entre los 45 y los 55 años, lo que hace que sea aún más complicado distinguirlos de la menopausia. La buena noticia es que un simple análisis de sangre puede ayudarlo a identificar si padece una o ambas afecciones. El tratamiento puede ser una terapia con hormona tiroidea o una cirugía, según la gravedad de tu condición tiroidea.
Tratamiento disponible para hipotiroidismo y menopausia
Tu médico te evaluará para diagnosticar la menopausia o una condición de la tiroides. Empieza por preguntarle a tu médico acerca de los análisis de sangre para comprobar tus niveles de:
Hormona estimulante del folículo (FSH) y estrógeno (estradiol): durante la menopausia, tus niveles de Hormona estimulante del folículo aumentarán y tus niveles de estradiol disminuirán.
Hormona estimulante de la tiroides (TSH): una tiroides poco activa (hipotiroidismo) causa síntomas muy similares a los de la menopausia.
Aunque no existe un tratamiento para la menopausia, existe un tratamiento para ayudar a aliviar los síntomas asociados con la menopausia. Algunos de estos tratamientos son:
Terapia hormonal: la terapia con estrógenos ayuda a aliviar los sofocos de la menopausia. Si todavía tienes tu útero, también necesitarás progestina además de estrógeno. El estrógeno también es útil en la prevención de la pérdida ósea, pero los riesgos del uso prolongado de la terapia hormonal pueden incluir problemas cardiovasculares y riesgos de cáncer de mama.
Estrógeno vaginal: la sequedad vaginal, las molestias durante las relaciones sexuales y algunos síntomas urinarios pueden aliviarse mediante el uso de una crema, tableta o anillo vaginal directamente en la vagina. Este tipo de tratamiento libera una pequeña cantidad de estrógeno que es absorbido por el tejido vaginal.
Antidepresivos de dosis baja: los sofocos menopáusicos también se pueden aliviar tomando ciertos antidepresivos llamados inhibidores selectivos de la recaptación de serotonina (ISRS). Las dosis bajas de ISRS para los sofocos pueden ser útiles para las mujeres que no pueden tomar estrógenos por razones de salud o para las mujeres que toman antidepresivos para un trastorno del estado de ánimo.
Gabapentina: otros nombres para este tratamiento son Gralise, Horizant y Neurontin. La gabapentina fue aprobada para tratar las convulsiones, pero se ha demostrado que reduce los sofocos. Esta es una alternativa para aliviar los sofocos en mujeres que no pueden usar estrógenos por razones de salud.
Clonidina: también llamada Catapres y Kapvay se usa para la presión arterial alta, pero también se puede usar para aliviar los sofocos.
Tratamiento para el hipotiroidismo
Dependiendo de tu situación específica, el tratamiento estándar para el hipotiroidismo son las hormonas tiroideas sintéticas. Tu médico calculará la dosis para comenzar, que probablemente deba ajustarse varias veces para asegurarse de que estás obteniendo la cantidad óptima de hormona tiroidea. La mayoría de las veces, las condiciones de la tiroides son a largo plazo, y es a través de prueba y error que encontrarás la dosis correcta de hormonas sintéticas para tomar. Los medicamentos disponibles para tratar el hipotiroidismo:
Synthroid
Levoxyl
Unithroid
Levotroide
Levotiroxina
Tirosint
Remedios caseros naturales para los síntomas de la menopausia y el trastorno de la tiroides
Suplementos de vitamina D: promueve la salud de los huesos y se puede tomar incluso si estás tomando hormonas tiroideas. Solo recuerda no tomar ningún medicamento al mismo tiempo que tu terapia de hormona tiroidea.
Yoga: el yoga es ideal para el insomnio, los cambios de humor e incluso puede ayudar con los sofocos. Los estudios han sugerido que el yoga puede ayudarte a dormir mejor y estabilizar tu estado de ánimo durante la perimenopausia.
Ginseng: el ginseng tiene cualidades calmantes y se ha utilizado como sedante en los países asiáticos durante siglos.
Consuma alimentos ricos en calcio; nuevamente, el calcio ayudará a promover huesos fuertes y disminuye el riesgo de osteoporosis
Los trastornos de la tiroides son más comunes de lo que crees
Según la Asociación Estadounidense de Tiroides, más del 12% de la población de EE. UU. desarrollará una condición de la tiroides durante su vida y, en este momento, se estima que 20 millones de estadounidenses tienen alguna forma de enfermedad de la tiroides. Desafortunadamente, las causas de los problemas de tiroides se desconocen en gran medida.
La menopausia no es una enfermedad, sino una parte natural de la vida. El hecho de que la tiroides no funcione correctamente es una condición que puede hacer que la menopausia sea un momento mucho más incómodo. Aunque los síntomas pueden ser difíciles de tratar, existen opciones para ayudar a aliviarlos y prevenirlos. Habla con tu médico acerca de hacerte las pruebas necesarias para saber exactamente dónde te encuentras, de modo que puedas estar en camino a sentirte mejor.
Enlaces:
WebMD - Thyroid and Menopause: Confusing the Symptoms
What to Know About Menopause if You Have Hypothyroidism
What Is Menopause?
Menopause
You Think It’s Menopause, But Could It Be Your Thyroid?
ATA - General Information
What You Should Know About Your Thyroid and Menopause
How the thyroid works during the menopausal transition
Role of Estrogen in Thyroid Function and Growth Regulation
Three stages of menopause
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Clonidine, sold as the brand name Catapres among others, is a medication used to treat high blood pressure, attention deficit hyperactivity disorder, drug withdrawal (alcohol, opioids, or smoking), menopausal flushing, diarrhea, and certain pain conditions.[7] It is used by mouth, by injection, or as a skin patch.[7] Onset of action is typically within an hour with the effects on blood pressure lasting for up to eight hours.[7]
Common side effect include dry mouth, dizziness, headaches, and sleepiness.[7] Severe side effects may include seeing or hearing things that other people do not, heart arrhythmias, and confusion.[8] If rapidly stopped, withdrawal effects may occur.[7] Use during pregnancy or breastfeeding is not recommended.[8] Clonidine lowers blood pressure by stimulating α2 receptors in the brain, which results in relaxation of many arteries.
While clonidine suppresses sympathetic outflow resulting in lower blood pressure, the sudden discontinuation can cause rebound hypertension due to a rebound in sympathetic outflow.[55]
Clonidine therapy should generally be gradually tapered when discontinuing therapy to avoid rebound effects from occurring. Treatment of clonidine withdrawal hypertension depends on the severity of the condition. Reintroduction of clonidine for mild cases, alpha and beta blockers for more urgent situations. Beta blockers never should be used alone to treat clonidine withdrawal as alpha vasoconstriction would still continue.[56][57]
In the setting of attention deficit hyperactivity disorder (ADHD), clonidine's molecular mechanism of action occurs due to its agonism at the alpha-2A adrenergic receptor, the subtype of the alpha-2 adrenergic receptor that is most principally found in the brain. Within the brain, the alpha-2A adrenergic receptors are found within the prefrontal cortex (PFC), among other areas. The alpha-2A adrenergic receptors are found on the presynaptic cleft of a given neuron, and, when activated by an agonist, the effect on downstream neurons is inhibitory. The inhibition is accomplished by preventing the secretion of the neurotransmitter norepinephrine. Thus, clonidine's agonism on alpha-2A adrenergic receptors in the PFC inhibits the action of downstream neurons by preventing the secretion of norepinephrine.[64]
This mechanism is similar to the brain's physiological inhibition of PFC neurons by the locus ceruleus (LC), which secretes norepinephrine into the PFC. Although norepinephrine can also bind to target adrenergic receptors on the downstream neuron (otherwise inducing a stimulatory effect), norepinephrine also binds to alpha-2A adrenergic receptors (akin to clonidine's mechanism of action), inhibiting the release of norepinephrine by that neuron and inducing an inhibitory effect. Because the PFC is required for working memory and attention, it is thought that clonidine's inhibition of PFC neurons helps to eliminate irrelevant attention (and subsequent behaviors), improving the person's focus and correcting deficits in attention.[64]
Clonidine treats high blood pressure by stimulating α2 receptors in the brain stem, which decreases peripheral vascular resistance, lowering blood pressure. It has specificity towards the presynaptic α2 receptors in the vasomotor center in the brainstem. This binding has a sympatholytic effect, suppresses release of norepinephrine, ATP, renin, and neuropeptide Y which if released would increase vascular resistance.[60]:201–203
Clonidine also acts as an agonist at imidazoline-1 (I1) receptors in the brain, and it is hypothesized that this effect may contribute to reducing blood pressure by reducing signaling in the sympathetic nervous system, but this effect acts upstream of the central α2 agonist effect of clonidine.[60]:201–203[61]
Clonidine also may cause bradycardia, probably by increasing signaling through the vagus nerve. When given intravenously, clonidine can temporarily increase blood pressure by stimulating α1 receptors in smooth muscles in blood vessels.[62] This hypertensive effect is not usual when clonidine is given by mouth or by the transdermal route.[60]:201–203
Plasma concentration of clonidine exceeding 2.0 ng/mL does not provide further blood pressure reduction.
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