#biofabricated

[bpod-bpod]

Layer upon Layer

Small volumes of cell-laden liquids in high-speed rotating tubular moulds create multi-layered tissue-like structures – a new, low-cost technology for bioengineering life-mimicking tissues

Read the published research paper here

Image from work by Ian Holland, Wenmiao Shu and Jamie A Davies

Deanery of Biomedical Science and the Centre for Engineering Biology, University of Edinburgh, Edinburgh and Department of Biomedical Engineering, University of Strathclyde, Glasgow, UK

Image contributed by and copyright held by Ian Holland

Published in Biofabrication, July 2023

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[techninja]

Advanced Biomanufacturing Solutions: How Biofabrication is Meeting the Need for Complex Biologics in the Biotechnology Industry

Biofabrication Market: A Growing Industry with Promising Future

Biofabrication is an emerging technological field that focuses on manufacturing structures for tissue engineering and regenerative medicine. This field has gained significant attention in recent years due to its potential to revolutionize the healthcare industry. In this article, we will explore the biofabrication market, its size, growth projections, and the key factors driving its growth.

Market Size and Growth Projections

The biofabrication market is expected to grow significantly in the coming years. According to a report by Intent Market Research, the global biofabrication market size is anticipated to reach USD 80 Billion by the end of 2036, growing at a CAGR of 10% during the forecast period, i.e., 2024-2036. Another report estimates the market size to be USD 22.76 Billion in 2023 and predicts it to reach USD 48.27 Billion by 2031, with a CAGR of 10.2% from 2024 to 2031.

Key Factors Driving Growth

Several factors are driving the growth of the biofabrication market. One of the primary factors is the increasing demand for biologics and biosimilars. The development of biologics accounts for around 40% of all pharmaceutical R&D spending, making it essential for advancing healthcare. Additionally, biomanufacturing accelerates scientific research, boosts economic growth, and provides jobs, making it a vital industry for the future.

Another key factor driving growth is the advancements in biofabrication techniques. Recent advancements in volumetric bioprinting, scaffold-free bioassembly, and hybrid biofabrication strategies have improved the scale, rate, and intricacy at which tissues can be fabricated. These advancements have the potential to recapitulate the structure and complexity of native tissues, making them suitable for various applications such as biomimetically engineered models for drug discovery, cosmetics testing, tissue regeneration, and medical devices.

Regional Analysis

The biofabrication market is expected to grow significantly in various regions. North America is expected to hold the largest share of 36% during the forecast period due to the robust presence of large biopharmaceutical businesses and the improved infrastructure in biological research. The Asia-Pacific region is expected to witness the fastest growth due to the rapid adoption of advanced technologies and the high prevalence of chronic diseases.

Competitive Landscape

The biofabrication market is highly competitive, with several key players operating in the market. Some of the major players include Applikon Biotechnology BV, bbi-biotech GmbH, Danaher Corporation, Eppendorf AG, Esco Group of Companies, GEA Group Aktiengesellschaft, Meissner Filtration Products, Inc., Merck KGaA, PBS Biotech, Inc., Pierre Guérin, Sartorius AG, Shanghai Bailun Biotechnology Co. Ltd., Solaris Biotechnology Srl., Thermo Fisher Scientific Inc., and ZETA GmbH.

Conclusion

In conclusion, the biofabrication market is expected to grow significantly in the coming years due to the increasing demand for biologics and biosimilars, advancements in biofabrication techniques, and the growing demand for advanced biomanufacturing solutions. The market is expected to be driven by key players operating in the market, and regional growth is expected to vary. As the industry continues to evolve, it is essential to stay updated on the latest advancements and trends to capitalize on the growth opportunities in the biofabrication market.

[outer-space-youtube]

Stars are Too Far?

This video inspired me to explain again why we don’t need to leave the Sol system or even go as far as Mars. If you haven’t heard, the solar systems in our galaxy are too far apart. As Einstein said, “Nothing moves faster than light.” It might not be a direct quote, but Faster Than Light travel is not going to happen, in our lifetime. How long will it take to fill the Sol System with Cylinders…

[market-insider]

Unveiling the Potential of 3D Bioprinting in Healthcare Markets

The global 3D bioprinting market size is expected to reach USD 5.3 billion by 2030, expanding at a CAGR of 12.5% over the forecast period, according to a new report by Grand View Research, Inc. Rising cases of COVID-19 and high prevalence of chronic diseases are some of the major factors contributing to the growth. During the outbreak of the pandemic, 3D printing has stepped up to become a vital technology to support improved healthcare and emergency response.

The COVID-19 epidemic is ever increasing since it was first identified in China in December 2019. Until January 12, 2021, more than 91.5 million cases of COVID-19 were reported globally, with more than 1,956,880 deaths, across the globe. This pandemic has fast-tracked the development of vaccine and drug testing.

3D Bioprinting Market Report Highlights

The medical segment accounted for the largest share of 37.6% in 2022 due to the increasing investment made in R&D

The magnetic levitation segment is anticipated to witness the highest CAGR of 13.7% over the forecast period due to technological development, and increasing adoption of magnetic levitation techniques by various innovators

North America dominated the market in 2022 with a share of 30.9%. Growing government expenditure on the healthcare industry is one of the major factors driving the market in this region

Some of the key players include Organovo; Envision TEC; Inventia Life Science PTY LTD; Poietis; Vivax Bio, LLC; Allevi; Cyfuse Biomedical K.K.; 3D Bioprinting Solutions; Cellink Global; Regemat 3D S.L.

For More Details or Sample Copy please visit link @: 3D Bioprinting Market Report

In the meantime, various 3D bioprinting companies are focused on the R&D of artificial tissues. With the help of U-FAB and other bioprinting technologies, CLECELL company has created respiratory epithelium artificial tissue which will help to prevent infection and tissue injury through the use of the mucociliary elevator.

The pandemic not only affected the well-being of people, but also affected the economy, and various other healthcare infrastructures worldwide. It severely disrupted the medical devices and pharmaceutical supply chains across the world. In such critical situations, various 3D bioprinting companies have created a global movement to supply emergency medical equipment such as ventilators, and personal protection equipment (PPE), to healthcare workers.

North America held the highest share of about 30.9% in 2022. Increasing adoption of 3D bioprinting for the production of medical products is expected to be one of the major factors contributing to market growth in this region. Whereas, Asia Pacific is anticipated to witness increased technological development in the pharmaceutical and biopharmaceutical sectors.

[solarpunkbusiness]

Mycotech: The Indonesian Startup Biofabricating novel materials from mushrooms

Called Mycotech Lab, the company was inspired by tempeh, the traditional Indonesian food made from fermented soybeans, and came up with its own technology to grow its ethical and carbon-friendly mycelium-based materials. 

Mycotech Lab decided to experiment with the fermentation process used to make tempeh to make a new fabric out of the complex root structure of mushrooms, otherwise known as mycelium. It was a lengthy trial-and-error process that kicked off in 2016, but “finally, we found one mushroom with a mycelium that can be made into binding material,” said Erlambang Ajidarma, head of research at the startup, in conversation with Reuters. 

The final product, developed with fungus grown on sawdust that then gets scraped off and dried and cut into different sizes, is Mylea, a fibrous but tough material that acts just like the real thing. It’s waterproof, pliable, durable, and most importantly, is far more sustainable than existing plastic-based synthetic leathers or carbon-intensive real leather made from hide. 

Mycotech also uses natural dye extracted from roots, leaves and food waste in the region to colour their leather alternative, which again is a process that is far less polluting than traditional tanning processes used for real cowhide that leaves behind solid and liquid waste that contains chromium and other hazardous compounds.

Since its inception, Mycotech has managed to grow its client base with no marketing budget because the demand for sustainable alternatives has grown alongside awareness of the damaging effects of animal-based materials in the fashion industry. 

We the Fungi

Bio Binderless Board | Sustainable non-adhesive binder board from Mylea™ byproduct to meet modern architectural and design standards

Biodegradable Solid-Composite | Utilizing mushroom mycelium that grows and is shaped into desired form and utilities.   

[semisolidmind]

Since Emi could actually indulge herself with Usagi bc he's sworn to protect and care for her, would she ever ask Usagi to be her body pillow/mattress? After a long time, of course. (Usagi would remain absolutely stoic while squealing internally) (Oh! And Usagi could use his ears to cover Emi's eyes from the morning sun too!)

she totally would. unlike most other apexes, Usagi's biofabric is softer, higher quality, like velveteen. by comparison, Uzu's biofabric is kinda course.

Usagi is an upgrade, Emi thinks guiltily. and he's so...quiet. Uzu didn't snore, really, but he was a lot louder than Usagi while relaxing. Emi feels bad comparing her two companions, but the differences are so striking.

Usagi, of course, maintains his composure while his princess sleeps on him. and though he isn't exactly squealing, he is very happy. he's never felt more content than when Emi is safely tucked up with him. he knows she doesn't feel quite as close to him as he'd like just yet, so he waits until he's sure she asleep before he tries petting her head and back. he likes nuzzling her hair, too.

she's always safe with him.

[groggfish]

Some work from this semester that I’m really proud of <333333 ⚾️🏠❤️‍🔥🥼🧑🏽‍🔬

[magnetarbeam]

Headcanonically, Tahiri identifies herself as a shaper, but the example of Scut from Mercy Kill leads me to believe that the safer term, in a post-Yuuzhan Vong War galaxy, is "biofabricator."

[materialsscienceandengineering]

Unusual interactions between polymers explain hydrogel formation

Many people use hydrogels without knowing it. As superabsorbents in nappies, for example, hydrogels absorb a lot of liquid. In the process, the initially dry material becomes jelly-like, but it does not wet. Some people place the swellable material on their eyeballs—soft contact lenses are also just hydrogels. The same goes for jelly and other everyday materials.

Hydrogels also play a role in science. From a chemical point of view, they are long, three-dimensionally cross-linked polymer molecules that form cavities. Inside, they can absorb and hold water molecules.

In the working group of former Würzburg chemistry professor Robert Luxenhofer, the suitability of hydrogels for biofabrication is being tested: For example, hydrogels can be used for 3D printing as scaffold structures, on which cells can be attached. In this way, for example, artificial tissues can be produced for medical research and regenerative therapies.

Read more.

[blogwelberfotos-blog]

NASA

[NASA HQ News] Estudantes de todos os EUA ouvirão o astronauta da NASA a bordo da estação espacial N Comunicados de imprensa da NASA para a NASA 1 dia atrásDetalhes Estudantes de todos os EUA ouvirão o astronauta da NASA a bordo da estação espacial 16 DE MAIO DE 2024

AVISO DE MÍDIA M24-068

Uma imagem da astronauta da NASA Jeanette Epps usando o porta-luvas BioFabrication Facility no Laboratório Europeu Columbus durante a Expedição 71 em 10 de abril de 2024.

Créditos: NASA/Michael Barratt

[heibaicnpost]

Sneakers 2.0 A Quantum Leap into the Future of Footwear

In the dynamic realm of fashion, Sneaker aren't just shoes; they're the oil upon which invention, culture, and technology meet. This composition envisions the coming phase in the elaboration of Sneaker, exploring the possibilities of Sneaker2.0 — a futuristic world where Rep Sneaker Website footwear becomes a amount vault into style, sustainability, and unknown functionality.

Biofabrication and Sustainable Luxury

The future of Sneaker embraces fabrication, where slice-edge technologies cultivate sustainable and atrocity-free accouterments. From lab-grown leather druthers to eco-friendly fabrics deduced from fungi, Sneaker2.0 is poised to review luxury with an environmentally conscious morality. These bioengineered accouterments not only minimize the carbon footmark but also open new avenues for avant-garde designs that seamlessly blend style and sustainability.

Responsive Material Morphing

Imagine Sneaker that acclimatize to your replica Sneakers  terrain and conditioning in real-time. Sneaker introduces responsive accouterments that transubstantiate and acclimate their parcels grounded on external factors — temperature, terrain, and indeed the wear and tear's physical condition. This invention ensures optimal comfort, support, and performance, steering in a period where the shoe becomes an extension of the body.

Holographic Design Interfaces

The design process takes a futuristic turn with holographic interfaces that allow consumers to customize their Sneaker in a three-dimensional virtual space. Sneaker suckers can experiment with holographic patterns, colors, and textures, creating bespoke designs before committing to the physical product. This immersive design experience revolutionizes personalization, making each brace of Sneaker a truly unique and individualized artifact.

Cradle-to-Cradle Circular Design

The Sneaker2.0 revolution extends beyond sustainable accouterments to embrace indirect design principles. Manufacturers are developing Sneaker with end-of-life considerations, icing that each element can be fluently disassembled, reclaimed, or upcycled. This cradle-to-cradle Replica Sneaker approach minimizes waste, paving the way for an unrestricted- circle system that aligns with eco-friendly values.

Neuro-Connected Smart Sneaker

The integration of smart technology takes a vault forward with Neuro-Connected Smart Sneaker. These intelligent shoes not only cover physical exertion but also dissect neurological signals to enhance performance and well-being. tailored feedback, stress reduction features, and cognitive performance optimization make Sneaker2.0 a holistic tool for both physical and internal heartiness.

Augmented Reality Virtual Sneaker Drops

In the Sneaker2.0 period, the excitement of limited releases and exclusive drops is elevated through stoked reality( AR). Virtual Sneaker drops bring the retail experience into consumers' homes, allowing them to nearly try on and witness the rearmost releases Snk Sneakers before making a purchase. This immersive approach transforms the act of buying v into a digital event, blending the virtual and physical worlds seamlessly.

Space-Age Accoutrements for Extreme Surroundings

Sneaker2.0 is designed to conquer extreme surroundings, drawing alleviation from space-age accouterments and technologies. From anti-gravity accouterments for enhanced comfort to heat-resistant fabrics for civic explorers, these Sneaker review what's possible in terms of continuity, functionality, and style.

Sneaker 2.0 heralds a new period where footwear goes beyond conventional boundaries. With sustainability at the van, innovative accouterments, responsive technologies, and futuristic design interfaces, these Sneaker come further than just a fashion statement — they are an amount vault into the future of footwear. As we venture into this uncharted home, Sneaker2.0 invites us to revise our relationship with fashion, technology, and the world we walk in. Step by step, the unborn unfolds beneath our bases.

[techninja]

The Art and Science of Biofabrication: Creating Life from Cells

Biofabrication Technology: Pioneering the Future of Medicine and Sustainability

Discover the transformative potential of biofabrication technology in healthcare and sustainability. Learn about applications, challenges, and future prospects in this comprehensive guide.

Biofabrication technology, a cutting-edge field at the intersection of biology and manufacturing, holds immense promise for revolutionizing various industries, particularly healthcare and sustainability. This article delves into the intricacies of biofabrication, its applications, challenges, and the transformative impact it promises to deliver.

Introduction to Biofabrication Technology

Biofabrication refers to the use of advanced manufacturing techniques to fabricate biological constructs such as tissues, organs, and even entire organisms. Unlike traditional manufacturing methods, biofabrication utilizes living cells, biomaterials, and biologically active molecules to create functional tissues and structures.

Understanding Biofabrication Processes

Additive Manufacturing Techniques

One of the key methodologies employed in biofabrication is additive manufacturing, commonly known as 3D printing. This process allows for precise layer-by-layer deposition of biomaterials, enabling the creation of complex structures with unprecedented accuracy and resolution.

Biomaterials Used in Biofabrication

Various biomaterials are utilized in biofabrication, including hydrogels, polymers, and decellularized matrices. These materials provide the necessary scaffolding and support for cell growth and tissue formation.

Applications of Biofabrication Technology

Biofabrication holds tremendous potential across a multitude of applications:

Medical Field

In medicine, biofabrication enables the creation of patient-specific tissues and organs for transplantation, reducing the risk of rejection and addressing the global organ shortage crisis.

Tissue Engineering

Biofabricated tissues can be utilized for regenerative medicine applications, including wound healing, bone repair, and the development of artificial skin substitutes.

Drug Testing and Delivery

Biofabricated models allow for more accurate and efficient drug testing, minimizing the need for animal testing and accelerating the drug development process.

Challenges and Limitations

Despite its vast potential, biofabrication faces several challenges:

Regulatory Hurdles

Regulatory frameworks governing the use of biofabricated products are still evolving, posing challenges for widespread adoption and commercialization.

Scalability Issues

Scaling up biofabrication processes to meet the demands of mass production remains a significant hurdle, particularly for complex organs and tissues.

Future Prospects and Innovations

The future of biofabrication holds exciting possibilities:

Bioprinting Organs

Researchers are actively working on bioprinting complex organs such as hearts, kidneys, and livers, offering hope for patients awaiting organ transplants.

Personalized Medicine

Biofabrication enables the customization of medical treatments based on individual patient profiles, leading to more effective and personalized healthcare solutions.

Ethical Considerations in Biofabrication

Biofabrication raises important ethical questions:

Animal Testing

The use of animal-derived cells and tissues in biofabrication processes raises concerns about animal welfare and the ethical implications of such practices.

Intellectual Property Rights

Issues surrounding patenting and ownership of biofabricated products raise complex ethical and legal dilemmas, requiring careful consideration.

Impact of Biofabrication on Sustainability

Biofabrication also holds promise for promoting sustainability:

Reduction in Waste

By enabling the production of tissues and organs on demand, biofabrication reduces the need for animal experimentation and minimizes biomedical waste.

Environmental Benefits

Biofabricated products have the potential to reduce the environmental footprint of traditional manufacturing processes, contributing to a more sustainable future.

Case Studies in Biofabrication

Several companies are leading the charge in biofabrication:

Organovo

Organovo specializes in bioprinting human tissues for pharmaceutical research and therapeutic applications, paving the way for personalized medicine.

Modern Meadow

Modern Meadow focuses on biofabricating animal-free leather and meat products, offering sustainable alternatives to traditional animal-derived materials.

Collaborations and Partnerships

Collaboration between academia, industry, and government is critical for advancing biofabrication:

Academic Institutions

Universities and research institutions play a pivotal role in driving innovation and pushing the boundaries of biofabrication technology.

Industry Leaders

Partnerships with industry leaders facilitate the translation of research findings into practical applications and commercial products.

Investment Trends in Biofabrication

The biofabrication industry is witnessing significant investment:

Venture Capital Funding

Venture capital firms are pouring funds into biofabrication startups, recognizing the immense potential for disruptive innovation in healthcare and sustainability.

Government Grants

Government agencies are also supporting biofabrication research through grants and funding opportunities, further fueling industry growth.

Educational Initiatives in Biofabrication

Educational programs are essential for nurturing the next generation of biofabrication experts:

Training Programs

Specialized training programs and courses equip students and professionals with the skills and knowledge needed to excel in the field of biofabrication.

Research Opportunities

Research institutions offer diverse opportunities for conducting groundbreaking research in biofabrication, driving innovation and discovery.

Global Adoption and Market Growth

Biofabrication is gaining traction worldwide:

Regions Leading in Biofabrication

Countries like the United States, Japan, and Germany are at the forefront of biofabrication research and innovation.

Market Size and Growth Projections

The global biofabrication market is poised for exponential growth, driven by increasing demand for personalized healthcare solutions and sustainable manufacturing practices.

Public Perception and Awareness

Public perception plays a crucial role in shaping the future of biofabrication:

Media Representation

Accurate and balanced media coverage is essential for fostering understanding and acceptance of biofabrication technology among the general public.

Public Acceptance

Building trust and transparency around biofabrication processes is essential for gaining public acceptance and overcoming skepticism.

Conclusion

In conclusion, biofabrication technology represents a paradigm shift in medicine and manufacturing, offering unprecedented opportunities for improving healthcare outcomes and promoting sustainability. Despite the challenges and ethical considerations, the future of biofabrication is bright, driven by innovation, collaboration, and a shared commitment to advancing human health and environmental stewardship.

FAQs on Biofabrication Technology

What is biofabrication technology?

How does biofabrication differ from traditional manufacturing methods?

What are the main applications of biofabrication?

What challenges does biofabrication face in terms of regulation and scalability?

How can biofabrication contribute to sustainability efforts?

[blogomonaco]

Tissue Engineering market

Biofabrication is an emerging field that combines the principles of tissue engineering with advanced manufacturing techniques to create complex three-dimensional tissues and organs.

Read More: https://blogconnoisseur.blogspot.com/2023/06/regenerative-medicine-unleashing.html