#SARS epidemic

[sophsweet]

Quotes from Coronavirus Vaccine Designers and Researchers since SARS-COV1

Coronavirus Vaccine History Back in 2004, SARS vaccine trial spotlights continued peril by Helen Pearson was published in the science press. But public-health experts remain concerned that a second wave of infections could erupt, either from human contact with infected animals or by the virus escaping from laboratory samples.Pearson, Helen SARS vaccine trial spotlights continued peril. Nature…

[covid-safer-hotties]

Also preserved in our archive (Daily updates!)

By Faras Ghani

Some 4.5 billion people worldwide are currently without adequate access to essential healthcare services, according to the World Health Organization (WHO).

This comes as more than 100,000 cases of mpox and at least 200 deaths have been confirmed globally, according to the European Centre for Disease Prevention and Control, with the WHO declaring it a public health emergency earlier this year.

The ongoing cholera outbreak in Sudan alone has affected almost 15,000 people with at least 473 deaths reported, according to the country’s health ministry.

A new COVID-19 variant has spread across 27 countries, infecting hundreds of people.

At the 2024 World Economic Summit, it was also revealed that antimicrobial resistance (AMR) has become the leading cause of death globally and could kill 10 million people by 2050.

A report titled Quantifying the Impact of Climate Change on Human Health, launched earlier this year, predicts that by 2050, an additional 14.5 million deaths could occur due to climate change as well as $12.5 trillion in economic losses globally.

With healthcare systems across the world already under extra stress, they could face an additional $1.1 trillion burden due to the impact of climate change, the report added.

Al Jazeera spoke to Dr Ahmed Ogwell, vice president of global health strategy at the United Nations Foundation and former deputy director general for the Africa Centres for Disease Control and Prevention (CDC), on the current state of healthcare, the risk of infections and diseases across the globe and whether the world has learned any lessons from the coronavirus pandemic.

Al Jazeera: Let’s start with the general health situation of the world. What risk level are we talking about with infections and diseases?

Ogwell: For the general health of the world, I’d put the temperature at moderate risk right now. We are in the middle of a public health emergency of international concern that is the mpox multi-country outbreak. It means that we need to be in heightened surveillance and ensuring we have the health tools that we need and that we also need to be improving the way we work together as a global community.

Secondly, there are increasing numbers of disease outbreaks – not just disease threats – including mpox, dengue fever, cholera, polio etc. And we still have effects of COVID on health systems. The world is still not comfortable when it comes to health issues.

Finally, the current geopolitical situation. We need to be coming together as a globe to address these issues because they are very international and cross-border in nature. But the situation is still hindering the delivery of a more united front to address global health. The world is at a moderate risk and can go either way, depending on what we do as a global community.

A heightened level of preparedness is required. There is a lot more we can do to make the situation more comfortable.

Al Jazeera: You spoke about preparedness. Is the world prepared for another pandemic? Did we learn any lessons from COVID?

Ogwell: Well, the lessons we should have learned from COVID, we did not. You see how we wore our masks, washed our hands, sanitised and kept our distance during the pandemic. Today, the situation has been completely forgotten. You don’t see anyone really wearing masks even when they are sneezing their heads off. That’s why we are struggling with controlling things we should have been able to.

At the healthcare level, the systems we put in place should have clicked in globally to address the potential outbreak of diseases. These systems were folded up when COVID passed. For example, the temperature scanning machines at airports. It means the very basic screening mechanism of someone who is feverish is not there.

At the policy level, during COVID we had vaccines being processed within six to seven months. But today, mpox has come and you don’t see the same urgency in trying to bring it under control. We have dengue fever and we don’t hear the same urgency. Policymakers are also seemingly not compelled to accommodate the lessons we should have learned from COVID.

Al Jazeera: You mentioned mpox. What is the situation with its spread and how worried should we be?

Ogwell: The risk is still high for spread because of the ease of communication that we have around the world today. The mode of transmission of mpox is close contact. Someone can carry it to another part of the world easily and can transfer it, setting off a chain that results in something bigger than it is right now.

In this world, an outbreak anywhere is a risk of an outbreak everywhere.

We need to put into good use the lessons of COVID, Ebola, cholera. All these outbreaks required solidarity across borders. Those who have the tools, resources and knowledge needed to address the outbreak, they need to provide support.

Al Jazeera: This solidarity, the geopolitical nature of the world today, where wars and conflict are aplenty, does not really work, right? How does this affect the state of global health?

Ogwell: Well, the reality on the ground is very different to a perfect world where the above would have worked well. The presence of humanitarian crises, where you find people living in very unsavoury conditions – being forced to consume very unhealthy water or food, forced to breathe very unhealthy air – the risks are twofold.

The first is the risk of contracting disease for the affected community whether it is IDPs or refugees in a conflict area or warzone. A situation like that becomes a breeding ground for new superbugs to develop. It may be that people there start getting used to difficult situations. When you start developing certain coping mechanisms, the bugs in you will also start adjusting to that new situation. If they get out in communities that are not under similar stressful circumstances, it becomes a new variant or a new type of resistance that developed with those bugs. The rest of the world immediately becomes at risk, whether it is a resistant variant or deadlier variant. And these environments, these conflict areas, can wreak havoc on the rest of the health system across the world.

Al Jazeera: Is climate change also playing its part forming these environments that you talked about?

Ogwell: Health is the face of climate change because it comes in a painful way. Communities that may not have experienced a certain disease are now areas being colonised by diseases that were only found in certain places because of these weather changes.

It is also the [duration] of conditions that gives rise to diseases. When there’s flooding and a lot of water stays for only a few hours, chances are slim that you’ll get water-borne disease. But if it stays for longer, the community may be affected.

As climate change continues to ravage the world, we find communities suffering for a long period. Natural disasters give rise to a situation where a disease can be able to grow.

Also, areas, for example, forests or glaciers, now become exposed to human beings. When we go into caves, forests and ocean depths that we have never been to, there may be bugs and pathogens that the human beings have never been in touch with. Because of the interaction due to climate change, those bugs, pathogens, animals, insects then get into the human population and we start seeing diseases never experienced before.

Al Jazeera: Let’s talk about healthcare. Some 4.5 billion people are currently without adequate access to essential healthcare services. Why is healthcare such a luxury?

Ogwell: It’s because of government investment in the health sector. Most governments have very low levels of investment there and this means that the vulnerable population is unable to access quality healthcare.

The second reason is the commercialisation of healthcare. It has been so heavily commercialised that you find in some jurisdictions the governments actually getting out of health services. You then have a population that is not heavily wealthy and it means the vulnerable are not going to have access to good healthcare, if any at all.

That commercialisation needs to be within certain parameters and boundaries so it doesn’t end up being a burden on the vulnerable.

This interview has been edited for clarity and length.

[theology101]

Something that I like to keep in the back of my head is that America is gonna have a HUGE population drop. And like, soon.

My mentor worked a lot in public health law and his wife worked for the CDC, so they both keep their fingers on the pulse of world health news. And right now, a new strain of Avian Flu had been making jumps cross species and across statelines - found in pigs and cows in Ohio, Michigan and New York.

If Avian flu becomes Humanized, and even a SMALL outbreak starts, millions of Americans will die.

COVID was 1-2% fatalities

Avian Flus average around 50.

COVID was directly transmissible, Avian Flu can survive after secondary and tertiary contact.

[ginaporterr]

Miss Jenn has a joke about the strike in 4x03 so i think he had some idea it was likely to happen but i do think he felt like it was a good time to end for story purposes

mhmmm def possible

[clarabowmp3]

Also it wasn’t just me (most of) the guys in my year are actually genetically shorter than they should be lmaoo

[safaakhatib]

Hi, I'm Safaa, a mother of two girls. I'm living through the horrors of war here as you read my message. I'm fighting death and running with my two children, wateen and Naya, from one place to another to save their lives. I'm escaping a real genocide and the spread of diseases and epidemics.

My husband is a journalist who was seriously injured in the head and almost killed while covering the events. I sincerely hope you can empathize with our dire situation and consider supporting us.

Your generosity has the potential to make a huge difference.

Please donate and/or share 🙏🏻

@sayruq @malcriada @riding-with-the-wild-hunt @appsa @sar-soor @nabulsi @heliopixels @just-browsing1222 @jezior0 @sar-soor @malcriada @monstermashpotato @mushroomjar @appsa @amaralesbian @arcaneglitch @mushroomjar @khizuo @river-to-sea @chingaderita @cherifaouachani

[transmutationisms]

ive been saying this for Literally Years Now but the most direct medical comparison to covid probably is never going to be HIV on any metric, overall it's probably the SARS outbreak of the early aughts (related viruses, similar transmission, what appear thus far to be similar rates/experiences of post-viral conditions and disability) and politically i do understand why people reach for HIV but like you really need to understand that our current situation is similar to how EVERY SINGLE pandemic / epidemic / outbreak has 'ended' in recent / capitalist history. these are political designations, that tend to get made once the ruling class considers itself safe, and it is typical that workers, global southerners, racialised people, &c continue to bear the brunt of diseases that would be treatable or preventable, were imperial countries and their ruling classes to care. we should be furious every time this happens and in every case where it is still happening: flu, TB, malaria, ebola, zika, plague, on and on, even the smallpox eradication campaign championed as a definitive triumph for public health occurred unevenly and the US and europe allowed the disease to continue to exact its most brutal toll on people in the Horn of Africa and southeast Asia until it was finally eradicated. covid is not unique in its medical OR political properties or ramifications, if you think it is you sorely need to do some more reading and this is why it is both unhelpful and yes, often homophobic to see how often 'covid communicators' jump straight to making alarmist and poorly contextualised comparisons to HIV, Specifically.

[marconswarehouse]

🚨💲80 Shohei Ohtani Angels Jerseys🚨

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[buttercuparry]

Emergency: Help Mahmoud purchase a tent!!

Mahmoud Hamam ( @ma7moudgaza2 ) severely needs your attention RIGHT NOW!! At the time of writing this, his family is struggling to survive in South of Gaza due to extreme heat. The tent Mahmoud and his family lives in now feels as if it is boiling them alive. There is no proper ventilation which adds to the misery and because of this, most of the time the family has to spend out in the streets-> this is an indignity, not to mention dangerous too as it makes them all the more prone to the bites of disease carrying insects.

The displacement camps are overcrowded, with open sewers and shared communal toilets. Skin infections and other epidemics have become common amongst the children. A proper tent would at least ensure that the children and the elderly family members have somewhere to retire to and rest if they feel sick. Which is why Mahmoud is asking you to spare only $700 USD at the moment.

Please help Mahmoud get to the short term goal of $6,469 USD Currently at $5,814 USD. His end goal is only 25k but right now he needs your help to raise 700 dollars. Boost and donate.

(Campaign has been shared by sar-soor)

[80eman]

I'm Eman Dalat Inshasi, lam 43 years old

A distress call from Gaza, a family searching for safety 🍉🙏🏻🍉🫶🙏🏻

A family trapped in Gaza asks for help to survive

Hello, I am Iman, 43 years old, a mother of nine children Abdul Rahman 27 years old, Montaha 25 years old, Fadl 23 years old, Amr 22 years old, Helen 19 years old, Dalia 16 years old, Shaza 14 years old, Dana 10 years old, Mohammed 8 years old I live in very difficult circumstances. My children and I lost our home and are now living in a tent amidst epidemics and diseases. We suffer from a lack of water, food, and treatment. Please help me and my children.

@ibtisam @riding-with-the-wild-hunt @vakarians-babe @7amaspayrollmanager @fairuzfakhira @fallahsart @sayruq @humanvoreture @kaapstadgirly @sar-soor @dimonds456-art @plomegranate @commissions4aid-international @nabulsi @stil-macher @soon-palestine @communitythings @palestinegenocide @vakarians-babe @ghost-and-a-half @7amaspayrollmanager @kaapstadgirly @annoyingloudmicrowavecultist @feluka @marnota @toughknit @flower-tea-fairies @the-stray-liger @riding-with-the-wild-hunt @vivisection-gf @communistchameleon @troythecatfish @the-bastard-king @4ft10tvlandfangirl

✅️Vetted by @gazavetters, my number verified on the list is ( #200 )✅️

[montahafamily]

Then don't forget from memory..🚨🚨🍉

"This is the famous story of my family's displacement"

Minutes was the story of our displacement, we fled from one danger to another, children screaming, adults in pain, we were left without carrying anything of our belongings, we left only with our souls that died from this crime. It consists of eleven individuals: the father, four sons and five daughters. The place where we lived is the original Khan Yunis area. We were displaced in mid-February 2024. Our planes now, after our fifth displacement, in a tent in the Mawasi area to the simplest necessities of life.

Here there is no water, no food, no medicine. Here you live amidst epidemics and diseases. Here your body turns into a fingerprint device for mal, dybab, awad and others. What I wrote is a small part of my great and ongoing suffering, if I wanted to talk in detail you would not have been able to imagine what is happening to us. I ask you to help the curricula that need you to bring them out of darkness into light. You are the hope of the great.

Support and share.

Thank you to everyone who believes in me. @gazavetters, currently in People is (#80)

Dear Palestine Supporter...

I saw your great interest in Palestinian campaigns, and it is a great honor for us. I am happy to meet you and talk to you. Please follow me so I can connect with you. ♥ ♥

@appsa @sar-soor @sayruq @stuckinapril @heritageposts @neptunerings @feluka @malcriada @queerstudiesnatural @brutaliakhoa

Vetted by @gazavetters, my number verified on the list is ( #80 )

[covid-safer-hotties]

Nasal COVID-19 vaccine halts transmission - Published July 31, 2024

Study in hamsters indicates vaccines targeting nose, mouth may be key to controlling spread of respiratory infections

A nasal COVID-19 vaccine blocks transmission of the virus, according to an animal study by researchers at Washington University School of Medicine in St. Louis. The findings suggest that vaccines delivered directly to the nose or mouth could play a critical role in containing the spread of respiratory infections.

The lightning-fast development of COVID-19 vaccines just months after the virus appeared was a triumph of modern science and saved millions of lives. But for all the good they did in reducing illnesses and deaths, the shots were unable to end the pandemic because of one notable weakness: They couldn’t stop the spread of the virus.

A new study by researchers at Washington University School of Medicine in St. Louis indicates that next-generation vaccines that target the virus’s points of entry — the nose and mouth — may be able to do what traditional shots cannot: contain the spread of respiratory infections and prevent transmission. Using a nasal COVID-19 vaccine based on Washington University technology, approved for use in India and licensed to Ocugen for further development in the U.S., the researchers showed that vaccinated hamsters that developed infections did not pass the virus on to others, breaking the cycle of transmission. In contrast, an approved COVID-19 vaccine that is injected failed to prevent the spread of the virus.

The findings, published July 31 in Science Advances, provide further evidence that so-called mucosal vaccines sprayed into the nose or dropped into the mouth may be the key to controlling respiratory infections such as influenza and COVID-19 that continue to circulate and cause significant illness and death.

“To prevent transmission, you need to keep the amount of virus in the upper airways low,” said senior author Jacco Boon, PhD, a professor of medicine, of molecular microbiology and of pathology & immunology. “The less virus that is there to begin with, the less likely you are to infect someone else if you cough or sneeze or even just breathe on them. This study shows that mucosal vaccines are superior to injected vaccines in terms of limiting viral replication in the upper airways and preventing spread to the next individual. In an epidemic or pandemic situation, this is the kind of vaccine you’re going to want.”

Developing vaccines that can control virus levels in the nose has proven challenging. Viruses such as influenza virus, SARS-CoV-2 (the virus that causes COVID-19) and respiratory syncytial virus (RSV) multiply rapidly in the nose and spread from person to person within a few days of initial exposure. Traditional injectable vaccines generate immune responses that can take a week to build to full strength and are much less potent in the nose than in the bloodstream, leaving the nose relatively unprotected against a fast-multiplying, fast-spreading virus.

In principle, a vaccine sprayed or dropped directly into the nose or mouth could limit viral reproduction and thereby reduce transmission by eliciting an immune response right where it’s needed most. But gathering evidence that mucosal vaccines actually do reduce transmission has proven tricky. Animal models of transmission are not well-established, and tracking person-to-person transmission is fiendishly complicated, given the number and variety of encounters a typical person has on any given day.

For this study, Boon and colleagues developed and validated a model for community transmission using hamsters and then used it to assess the effect of mucosal vaccination on the spread of SARS-CoV-2. (Unlike mice, hamsters are naturally susceptible to infection with SARS-CoV-2, making them the ideal laboratory animals for a transmission study.)

The researchers immunized groups of hamsters with laboratory versions of approved COVID-19 vaccines: the nasal iNCOVACC used in India or the injected Pfizer vaccine. For comparison, some hamsters were not immunized. After giving the vaccinated hamsters a few weeks for their immune responses to fully mature, the researchers infected other hamsters with SARS-CoV-2 and then placed the immunized hamsters with the infected hamsters for eight hours. This first step of the experiment mimics the experience of vaccinated people who are exposed to a person with COVID-19.

After spending eight hours rubbing shoulders with infected hamsters, most of the vaccinated animals became infected. Virus was found in the noses and lungs of 12 of 14 (86%) hamsters that had received the nasal vaccine, and 15 of 16 (94%) hamsters that had received the injected vaccine. Importantly, while most animals in both groups were infected, they weren’t infected to the same degree. Hamsters that had been nasally immunized had virus levels in the airways 100 to 100,000 times lower than those that had received the shot or had not been vaccinated. The study did not assess the animals’ health, but previous studies have shown that both vaccines reduce the likelihood of severe illness and death from COVID-19.

The second step of the experiment yielded even more striking results. The researchers took vaccinated hamsters that subsequently developed infections and placed them with healthy vaccinated and unvaccinated hamsters for eight hours to model transmission of virus from a vaccinated person to others.

None of the hamsters that were exposed to nasally vaccinated hamsters became infected, regardless of whether the recipient hamster had been vaccinated or not. In contrast, roughly half of the hamsters that were exposed to hamsters vaccinated by injection became infected — again, regardless of the recipient’s immunization status. In other words, vaccination through the nose — but not by injection — broke the cycle of transmission.

These data, Boon said, could be important as the world prepares for the possibility that avian influenza, currently causing an outbreak in dairy cows, might adapt to humans and trigger a flu epidemic. An injectable vaccine for avian influenza already exists, and a team of researchers at Washington University is working toward a nasal vaccine for avian influenza. That team includes Boon and co-author Michael S. Diamond, MD, PhD, the Herbert S. Gasser Professor of Medicine and one of the inventors of the nasal vaccine technology used in this paper.

“Mucosal vaccines are the future of vaccines for respiratory infections,” Boon said. “Historically, developing such vaccines has been challenging. There’s still so much we don’t know about the kind of immune response we need and how to elicit it. I think we’re going to see a lot of very exciting research in the next few years that could lead to big improvements in vaccines for respiratory infections.”

Study linked in the first link!

[shah599]

Painful reality 💔

We live under an unknown future. We do not know what is coming. We live under famine, begging, diseases, epidemics, poverty, displacement, homelessness, killing, destruction and bombing. What is this world, why is there so much injustice? I cannot continue my life You are our last hope

@apol @appsa @buttercuparry @malcriada @palestinegenocide-blog @orble @sar-soor @akajustmerry @annoyingloudmicrowavecultist @feluka @marnosso-blog @sayruq @tortiefrancis @flower-tea-fairies @tsaricides @riding-with-the-wild-hunt @visenyasdragon @belleandsaintsebastian @ear-motif @kordeliiius @communistkenobi @brutaliakhoa @raelyn-dreams @troythecatfish @the-quasar-hero @tamarrud @4ft10tvlandfangirl @queerstudiesnatural @northgazaupdates2 @skatezophrenic @awetistic-things @baby-girl-aaron-dessner @nabulsi

[princegaza]

🚨🚨🚨Urgent for you save childhood in Palestine🇵🇸🇵🇸🇵🇸🇵🇸🇵🇸

🍉🍉🍉🍉🍉This is the daily suffering of my son Abdul Rahman while transporting water for drinking, which is not suitable for human consumption due to the shutdown of desalination plants and their complete destruction in the Gaza Strip from north to south.

With your support, re-publishing and donating at least 5 euros, you will make a difference and save Abdul Rahman and his family from genocide, which has several means, including killing, death by hunger or thirst, and the spread of diseases and epidemics due to the shutdown of sewage and desalination plants, and there is no water for cleaning.

Do not hesitate to be with us, help us and contribute to saving my family‼️. 🙏 🌹.

they have been verified on @/el-shab-hussein's and @/nabulsi's list of vetted fundraisers here (#250, line 254)

@heba-20 @soon-palestine @el-shab-hussein @ibtisams-blog @marnota @riding-with-the-wild-hunt @i-am-aprl @northgazaupdates2 @fallahifag @fairuzfan @sar-soor @90-ghost @hellspawnelf @aroacekitty @ttohrus @proheromidoriyashouto @quagsiredoesnotfuck @turian @iamjustthinkin @genera1kenobi @fireyfobbitmedicine @tasteofyourblood @lesbianmaxevans @chimney-begins @ratmanwalking @aleksstroud @shellofashadow @ibtisams-blog @buttercuparry @wlwaerith @vetted-gaza-funds @sayrunhh @ripe @straycatj @thunderstruck9 @haflacky @catasters @northgazaupdates2 @northwezt @northernsiberiawinds

[noorplog17]

Hello, I am Noor, my family consists of five members and we live in Khan Younis, I am 19 years old. I was at the beginning of my university life and studying engineering. My dreams were shattered and my future was lost because of the war and its horrors. We were living a quiet and safe life before the war.💔

Suddenly, these events broke The events are a curse to destroy our lives in the Gaza Strip and our house in Khan Younis was destroyed and exposed to continuous displacement. We have suffered for more than 260 days of destruction, displacement, continuous bombardment and constant fear. 🍉

We have survived four previous wars and more than 17 military escalations, but this war has been different … 🇵🇸

since it broke out on Gaza on October 7, and nowadays we live in the tent amid the atmosphere of cold and widespread epidemics, please help us💔

@ibtisams @tsaricides @riding-with-the-wild-hunt @belleandsaintsebastian @beserkerjewel @buttonpoetry @bananahirl@buggie-colors @90-ghost @skatehardorskatehome @awetistic-things @gentl @mooshro0ms @vampiretranscending @sar-soor @blossomdan @vakarians-babe @villadiodatis @perrfectly @ashwantsafreepalestine @pls-noraneko

[darkmaga-returns]

A Scientific Explanation of the Fraud of RT-PCR Testing for COVID-19

Corinne Michels

Nov 05, 2024

“The COVID-19 PCR tests were a fraud.” You have heard this before, but is it true or just more hype? Read this report and decide for yourself. It explains the fundamentals of the RT-PCR (Reverse Transcriptase - Polymerase Chain Reaction) test kits for those who want to understand the facts. Do not expect an easy read. For starters, you will need to familiarize yourself with the basic structure of DNA. Understanding how misinterpretation of the RT-PCR test results was used to create the COVID-19 pandemic will be your reward. You will be immunized against future efforts to create fear and societal discord. Rest assured; they will try again!

A serious flu-like respiratory disease began to spread in early Fall 2019 with Wuhan, China, as “ground zero.” By December, worldwide spread of the disease was underway. Images of hapless pedestrians suddenly falling dead in the streets; overwhelmed hospitals in Lombardy, Italy; government-imposed lockdowns; and nonstop coverage of worldwide COVID deaths fanned the flames of fear surrounding this unknown disease. It was not enough to be symptom-free. People demanded the development of a test to detect silent carriers of the infectious agent.

Only the genome sequence of SARS-CoV-2 was known at the time, and the only available testing method used polymerase chain reaction, a.k.a. PCR. Despite many known contraindications, RT-PCR widespread testing for COVID-19 began. According to Dr. Trish M. Perl, an epidemiologist at Johns Hopkins and past president of the Society of Health Care Epidemiologists of America, blind faith in the results of technically complex molecular tests results in “pseudo-epidemics.”  [https://www.nytimes.com/2007/01/22/health/22whoop.html] The COVID-19 pandemic was one of those.