#Protein Production Technologies

[123567-9qaaq9]

Protein Production Technologies Market  Outlines, Future Trends, Insight And Quality Analysis 

Protein production technologies encompass a diverse array of methods and techniques aimed at generating proteins for various applications, including research, pharmaceuticals, biotechnology, and industrial processes.

The Protein Production Technologies Market   was valued at $2,393.0 million in 2023 and is expected to reach $6,963.6 million by 2033, growing at a CAGR of 11.27% between 2023 and 2033

Protein Production Technologies Overview 

Protein production technologies play a pivotal role in modern biotechnology, pharmaceuticals, and scientific research by enabling the generation of proteins with diverse functions and applications. 

These technologies encompass a wide range of methods and techniques tailored to meet specific needs, from producing therapeutic proteins for treating diseases to generating enzymes for industrial processes. 

Market Segmentation

Segmentation 1: By Application

Segmentation 2: By End User 

Segmentation 3: By Product

Segmentation 4: By Expression System

Segmentation 5: By Region

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Application for Protein Production Technologies Market   

Disease Discovery and Development 

Personalized Medicine 

Agricultural Biotechnology 

Agricultural Biotechnology 

Industrial Enzymes and Biocatalysts 

Key Market Players 

Agilent Technologies, Inc.

Bio-Rad Laboratories, Inc.

Charles River Laboratories International, Inc.

Danaher Corporation (Abcam plc.)

GenCefe Co., Ltd.

Genscript Biotech Corporation

And many others 

Common protein production technologies include

Cell Culture-Based Methods

Microbial Fermentation

Transgenic Organisms

Mammalian Cell Expression Systems

Cell-Free Protein Synthesis

Market Drivers 

Biopharmaceutical Development 

Rapid Advances in Life Sciences 

Personalized Medicines 

Increasing Prevalence of Chronic Diseases 

Industrial Biotechnology 

Technological Advancements 

 Visit our Life Sciences & Biopharma page for better understanding 

Key factors contributing to the growth of the Protein Production Technologies Market   

Expanding Biopharmaceutical Industry 

Rise in Chronic and Infectious Diseases 

Rising Investments in Biotechnology and Life Sciences

Shift Towards Personalized Medicine

Emergence of Biosimilars and Biogenerics

Recent Developments in the Recombinant Protein Production Technologies Market  

In January 2024, Evosep, a leader in sample preparation for mass spectrometry-based proteomics, partnered with Thermo Fisher Scientific Inc., a global scientific leader, to advance clinical proteomics research. This collaboration would combine Evosep's sample separation technology with Thermo Fisher Scientific Inc.'s mass spectrometry instruments, enhancing proteomics research capabilities.release would support pharmaceutical and biotechnology companies engaged in the manufacturing of therapeutic proteins, with the goal of improving product quality and expediting time-to-market.

Key Questions Answered 

Q What is the estimated global market size for the Protein Production Technologies Market  ?

Q What are the future trends expected in the Protein Production Technologies Market  ?

Q What does the supply chain and value chain of the Protein Production Technologies Market   look like?

Q  What is the regulatory framework of the Protein Production Technologies Market  ?

Q How has the COVID-19 outbreak affected the future trajectory of the Protein Production Technologies Market  ?

Q What are the market entry barriers and opportunities in the Protein Production Technologies Market  ?

Q What are the major market drivers, challenges, and opportunities of the Protein Production Technologies Market  ?

Q How is each segment of the Protein Production Technologies Market   expected to grow during the forecast period, and what is the anticipated revenue generated by each of the segments by the end of 2033?

Q What is the growth potential of the global Protein Production Technologies Market   in North America, Europe, Asia-Pacific, Latin America, and Rest-of-the-World, and what are the driving and challenging factors of the market in each of these regions?

Q Who are the leading players with significant offerings in the Protein Production Technologies Market  , and what is the current market dominance for each of these leading players? Who are the next frontiers in the Protein Production Technologies Market  ?

Conclusion 

In conclusion, protein production technologies represent a dynamic and indispensable facet of modern biotechnology, pharmaceuticals, and scientific research.

Driven by factors such as the expanding biopharmaceutical industry, technological advancements, increasing R&D activities, and regulatory support, the protein production technologies market continues to experience robust growth. 

As protein-based therapeutics and biologics continue to revolutionize healthcare and biomanufacturing, investment in protein production technologies is poised to drive innovation, accelerate drug discovery and development, and ultimately improve patient outcomes.

[kosheeka]

Recombinant Protein Technology

As per the central dogma, protein production by translation is possible after RNA transcription and it all begins with DNA replication. In simpler terms, DNA sequence provides instructions for protein synthesis, and thus a gene expression results in protein expression. The recombinant DNA technology, also known as DNA cloning or gene cloning, involves the transfer of foreign DNA into an organism, leading to the amplification of the foreign DNA followed by protein expression of the related gene. 

[headspace-hotel]

I went down the internet rabbit hole trying to figure out wtf vegan cheese is made of and I found articles like this one speaking praises of new food tech startups creating vegan alternatives to cheese that Actually work like cheese in cooking so I was like huh that's neat and I looked up more stuff about 'precision fermentation' and. This is not good.

Basically these new biotech companies are pressuring governments to let them build a ton of new factories and pushing for governments to pay for them or to provide tax breaks and subsidies, and the factories are gonna cost hundreds of millions of dollars and require energy sources. Like, these things will have to be expensive and HUGE

I feel like I've just uncovered the tip of the "lab grown meat" iceberg. There are a bajillion of these companies (the one mentioned in the first article a $750 MILLION tech startup) that are trying to create "animal-free" animal products using biotech and want to build large factories to do it on a large scale

I'm trying to use google to find out about the energy requirements of such facilities and everything is really vague and hand-wavey about it like this article that's like "weeeeeell electricity can be produced using renewables" but it does take a lot of electricity, sugars, and human labor. Most of the claims about its sustainability appear to assume that we switch over to renewable electricity sources and/or use processes that don't fully exist yet.

I finally tracked down the source of some of the more radical claims about precision fermentation, and it comes from a think tank RethinkX that released a report claiming that the livestock industry will collapse by 2030, and be replaced by a system they're calling...

Food-as-Software, in which individual molecules engineered by scientists are uploaded to databases – molecular cookbooks that food engineers anywhere in the world can use to design products in the same way that software developers design apps.

I'm finding it hard to be excited about this for some odd reason

Where's the evidence for lower environmental impacts. That's literally what we're here for.

There will be an increase in the amount of electricity used in the new food system as the production facilities that underpin it rely on electricity to operate.

well that doesn't sound good.

This will, however, be offset by reductions in energy use elsewhere along the value chain. For example, since modern meat and dairy products will be produced in a sterile environment where the risk of contamination by pathogens is low, the need for refrigeration in storage and retail will decrease significantly.

Oh, so it will be better for the Earth because...we won't need to refrigerate. ????????

Oh Lord Jesus give me some numerical values.

Modern foods will be about 10 times more efficient than a cow at converting feed into end products because a cow needs energy via feed to maintain and build its body over time. Less feed consumed means less land required to grow it, which means less water is used and less waste is produced. The savings are dramatic – more than 10-25 times less feedstock, 10 times less water, five times less energy and 100 times less land.

There is nothing else in this report that I can find that provides evidence for a lower carbon footprint. Supposedly, an egg white protein produced through a similar process has been found to reduce environmental impacts, but mostly everything seems very speculative.

And crucially none of these estimations are taking into account the enormous cost and resource investment of constructing large factories that use this technology in the first place (existing use is mostly for pharmaceutical purposes)

It seems like there are more tech startups attempting to use this technology to create food than individual scientific papers investigating whether it's a good idea. Seriously, Google Scholar and JSTOR have almost nothing. The tech of the sort that RethinkX is describing barely exists.

Apparently Liberation Labs is planning to build the first large-scale precision fermentation facility in Richmond, Indiana come 2024 because of the presence of "a workforce experienced in manufacturing"

And I just looked up Richmond, Indiana and apparently, as of RIGHT NOW, the town is in the aftermath of a huge fire at a plastics recycling plant and is full of toxic debris containing asbestos and the air is full of toxic VOCs and hydrogen cyanide. ???????????? So that's how having a robust industrial sector is working out for them so far.

[natalievoncatte]

“Hey,” Kara said, “want to grab something for lunch?”

Seated at her desk, Lena waved her hand dismissively, even though she was only talking to Kara on the phone.

“I can’t. I have too much to do.”

“You’re the boss, you can just take off. Everyone has to do what you say.”

Lena rolled her eyes. There was a hint of teasing in Kara’s voice, but Lena meant it. L-Corp was in the final stages of a major acquisition. Lena was taking over an AI startup that was developing a key technology for one of her medical division products, and to make it viable she needed their patents, IP, and scientific talent.

“I really am swamped.”

“Can’t you spare half an hour? For me? I want to make sure you’re not starving yourself again.”

Lena sighed. The teasing was replaced with a genuine concern, now. Lena had admitted to Kara that she lost five the last time she got caught up in something for three weeks. Of everyone she mentioned it to, Kara was the only one who didn’t congratulate her. She worried, she fussed, and she fed Lena that night.

“Okay,” said Lena. “I’ll meet you in the lobby in ten, does that sound…”

“I’m already here.”

Kara then opened the door and walked in, smirking. Lena’s breath caught when she saw her. Kara had her hair in an elaborate braid and was dressed for the blistering summer heat in a green sun dress and sandals. Joy sparkled in her blue eyes and she smiled wide.

“We could get delivery,” said Lena.

“Nope! Fresh air! It’s good for you!”

Lena sighed and allowed herself to be bundle outside, throwing on a hat and sunglasses. Since she was in the office on a Saturday and had let herself in, she had dressed casually and the heat was tolerable while they walked.

They spent the trip in companionable silence. Kara walked close to her, a presence just to Lena’s right that seemed to electrify the air, like something pulling between them.

Lena noticed things. Like how Kara always walked between her and the road, and how the way her arms would swing always seemed to leave Kara’s pinky brushing the outside of Lena’s hand. Sometimes she’d mumble an apology. Sometimes not. Sometimes Lena would feel the tender touch, and find Kara looking at her oddly, a soft wistful smile on her face that made Lena melt.

Sometimes she thought about catching her hand. Sometimes she thought about stopping and meeting that look, gently asking what Kara was so intent about. She never did, because as much as she enjoyed that fluttering feeling in her belly, she was certain Kara was straight.

It was like an ache she just couldn’t stop, dull and pulsing at the back of her mind. One soft brush of Kara’s lips on her own would be more than-

“Hey,” Kara said. “You’re a million miles away.”

“Oh,” Lena murmured, realizing that she’d been staring this time. “I’m sorry, I was just thinking about work.”

There was a nearly imperceptible flash of concern and sadness on Kara’s face, the tiniest hint of a frown that made Lena want to cup her cheek and whisper an apology, but didn’t.

“This is it,” said Kara. “Try to relax, alright?”

Lena sighed her best promise and followed Kara in to a quaint little lunch spot with air conditioning and big ceiling fans mounted high overhead, and they took their seats.

Kara ordered for her -you need protein, Lena!- and she spent the next forty-five minutes picking at a turkey wrap and listening to Kara chatter excitedly about gossip and work and who was dating who at CatCo and a big story she was working on. Lena knew she had a lopsided smile on her face and was nodding along, as much for the delight of Kara’s excitement. She did little voices when she imitated her coworkers and got animated when talking about her story.

Lena barely said a word.

“You’re quiet,” Kara finally said.

I’m in love with you, Lena thought.

“I’m just tired. I was listening. You think Elliot is dating… Katie?”

Kara smirked at her.

“I wish you wouldn’t push yourself so hard. There’s more to life than work.”

Kara rested her hand atop Lena’s, and Lena felt her heart flip in her chest.

“I know. I’m sorry I’ve been distant, this project just means a lot to me.”

“Let’s get you back before the building burns down,” said Kara.

Lena felt a little guilty as they walked into the bar to pay the bill. For some reason, Lena felt a little thrill when Kara insisted on paying, and the host looked at Lena and then smirked at Kara.

They turned, snd a man stepped up to Lena.

“Luthor!” he shouted. “You ruined my fucking life!”

Lena froze, wide-eyed, about to ask what she did. The man raised the gun he had hidden in the pocket of his sweatshirt and fired. The sound was incredible, stabbing at her ear drums and filling the world with a dull ringing. She stumbled back into the bar.

Kara’s fist was clenched in front of her chest, her eyes wide and expression wild. Kara snapped her attention to the gunman, who fired again.

She stepped between the gun and Lena. Five more shots went off and seemed to rumple her dress with tiny bursts of wind, but then Lena saw the bullets had torn the fabric before they tumbled to the floor.

Kara swept her hand and yanked the gun out of his hand, and it fell to the floor in a crumpled mass, sliding along the tiles.

She changed. It was as if she grew taller, wider, expression hardening. She grabbed the attacker by his collar and hauled him off the floor with one hand, and Lena felt a pang of fear as fire literally blazed in her eyes.

When she put a hand on Kara’s shoulder, the muscles were coiled like steel cables.

“Don’t” she caught herself whispering.

Kara threw him. He slid across the floor and thumped against the wall, and she strode over and planted her foot on his chest, easily pinning him. He stared up at her in naked shock.

Kara touched her ear. “Alex, get to my location asap. Someone just tried to kill Lena. We need a cleanup.”

Lena stared at her.

It wasn’t five minutes before her sister, in full tactical gear, led a team of armed agents into the cafe and bundled up Lena’s assailant, dragging him away. They took the crumpled gun and the fallen bullets and began talking to the other patrons and staff.

Lena started to shake.

Kara focused on her instantly and led her outside, where “FBI” vans were waiting. Kara stepped into one and in half a second, without seeming to break stride, stepped back into view in full Supergirl regalia.

Lena almost fell. He knees went wobbly and she slumped, right into Kara’s arms. Kara scooped her up in a single fluid motion and lifted off as Lena took a death grip on the collar of her suit and buried her face in Kara’s neck.

Moments later they lighted on Lena’s balcony. Kara pushed the door aside, ignoring the very expensive lock that popped off as she did, and carried her inside.

Bolting, Lena ran to the bathroom. Her entire body had gone cold, like she’d been dunked in ice water. She sagged to her knees and grabbed the toilet, retching.

Kara was there. A soft, reassuring hand rubbed her back while the other tenderly and expertly gathered her hair. Lena couldn’t help it; she struggled to hold on her lunch, shaking, screaming between retches.

“You’re alright, I’ve got you.”

“He almost killed me,” Lena choked out. “If you weren’t there I’d be dead.”

Kara sat down, and pulled Lena into her lap, rocking her softly until the shaking subsided before standing up, easily carrying her out of the room.

A glass of water helped. Kara was attentive, gently, softly encouraging while the adrenaline shakes ravaged Lena.

Kara was Supergirl. It seemed weirdly obvious to her now. She looked up and realized that Kara hadn’t unbraided her hair, and the effect was disconcerting. Kara took Lena in her arms again, hugging her tight.

“You’re safe. I’ve got you, you’re safe now.”

Lena took in a deep breath, drinking her scent as Kara rubbed her back and did the same, burying her face in Lena’s hair.

“You’re going to be okay,” Kara murmured, “it’s alright.”

“I’m so tired of this,” Lena whimpered. “What did I do? Why did he want to hurt me?”

“You don’t deserve to live this way,” said Kara.

“Oh God,” said Lena. “I have to… the acquisition, my work…”

Kara seized her head in her hands, firmly yet gently, cupping Lena’s cheeks in her palms. Kara stared at her with shocking intensity, tears welling up in her eyes.

“Fuck your work,” Kara almost shouted. “I care about you. You, Lena! You’re more than… you… I…”

Lena stared back at her, in shock at the intensity in her voice, even moreso than the out of character f-bomb. Kara was still holding her, looking at her with such fullness of feeling, biting her lip and struggling to hold back tears and failing, that Lena couldn’t stop herself. She lunged, diving into Kara, hugging her.

Lena hugged Kara, but Kara was the one to kiss her first. Their lips met in a nearly painful crash, Kara diving into her like she might never see her again.

Oh.

It was a wild sensation, this adrenaline shock combined with the feeling of Kara’s powerful arms wrapped around her, fingers that could crush diamonds gripping her hip and the back of her neck, the way Kara stood tall over her and her boots thumped on the floor when she took a step.

“You mean everything to me.”

Lena sucked in a breath and swallowed a sob.

Oh.

“Don’t leave,” Lena chirped out. “Please don’t leave me.”

“I won’t. I won’t.”

Lena finally felt herself slowing down, but it left her drained, barely able to stand. She slumped against Kara and stayed there, clinging to her.

“I’m going to change,” Kara murmured. “Easy.”

She lowered Lena onto the sofa and she curled in the corner, huddled in a ball.

Then Kara reached to her shoulders unclasped one side of her cape, then the other. With a flourish she swung it wide and swept it over Lena as a blanket.

“Stay right here.”

She wasn’t gone long. In mere moments she was there in a t-shirt and shorts, wrapping herself around Lena.

It took hours for Lena to finally calm down, and by then she’d fallen asleep on Kara’s shoulder. When she woke up, Kara was teasing her fingers along Lena’s scalp and singing softly. It took a moment for Lena to realize that the clipped, rhythmic language had to be Kryptonian.

“Are you okay?”

Lena nodded.

“It was different this time. People have tried to kill me before but… it was different. He was just some guy in a cafe.”

“Lena,” Kara murmured, “look at me.”

Lena looked up, meeting Kara’s soft, intent gaze.

“I won’t let anyone hurt you.”

Lena’s heart swelled. It felt so real, so true. Kara meant it, every bit of it, from the depths of her being. Lena tucked in closer to her and sighed on her shoulder.

“Work can wait until Monday,” Lena whispered.

“Tuesday,” Kara corrected.

“Can you stay tonight?” said Lena. “Just to sleep,” she added.

“Of course.”

They were silent to a while.

“Lena?”

“Yeah.”

“About earlier, if I… overstepped, I’m sorry. It doesn’t have to mean anything if you don’t want it to.”

Lena sucked in a sharp breath.

“It means everything.”

“Oh,” said Kara.

[reasonsforhope]

"Scientists have developed a way to dramatically reduce the cost of recycling certain electronic waste by using whey protein.

Their method allows for the easy recovery of gold from circuit boards at a cost of energy and materials amounting to 50 times less than the price of the gold they recover—these are the numbers that big business likes to see.

Indeed, the potential for scalability depends on this sort of cost savings, something traditional e-waste recycling methods just can’t achieve.

Professor Raffaele Mezzenga from ETH Zurich has found that whey protein, a byproduct of dairy manufacturing, can be used to make sponges that attract trace amounts of ionized gold.

Electronic waste contains a variety of valuable metals, including copper, cobalt, and gold. Despite gold’s public persona as being either money or jewelry, thousands of ounces of gold are used in electronics every year for its exceptional conductive properties.

Mezzenga’s colleague Mohammad Peydayesh first “denatured whey proteins under acidic conditions and high temperatures, so that they aggregated into protein nanofibrils in a gel,” writes the ETH Zurich press. “The scientists then dried the gel, creating a sponge out of these protein fibrils.”

The next step was extracting the gold: done by tossing 20 salvaged motherboards into an acid bath until the metals had dissolved into ionized compounds that the sponge began attracting.

Removing the sponge, a heat treatment caused the gold ions to aggregate into 22-carat gold flakes which could be easily removed.

“The fact I love the most is that we’re using a food industry byproduct to obtain gold from electronic waste,” Mezzenga says. In a very real sense, he observes, the method transforms two waste products into gold. “You can’t get much more sustainable than that!” ...

However the real dollar value comes from the bottom line—which was 50 times more than the cost of energy and source materials. Because of this, the scientists have every intention of bringing the technology to the market as quickly as possible while also desiring to see if the protein fibril sponge can be made of other food waste byproducts.

E-waste is a quickly growing burden in global landfills, and recycling it requires extremely energy-intensive machinery that many recycling facilities do not possess.

The environmental value of the minerals contained within most e-waste comes not only from preventing the hundreds of years it takes for them to break down in the soil, but also from the reduction in demand from new mining operations which can, though not always, significantly degrade the environments they are located in.

[Note: Absolutely massive understatement, mining is incredibly destructive to ecosystems. Mining is also incredibly toxic to human health and a major cause of conflict, displacement, and slavery globally.]

Other countries are trying to incentivize the recycling of e-waste, and are using gold to do so. In 2022, GNN reported that the British Royal Mint launched an electronically traded fund (ETF) with each share representing the value of gold recovered from e-waste as a way for investors to diversify into gold in a way that doesn’t support environmentally damaging mining.

The breakthrough is reminiscent of that old fairy tale of Rumpelstiltskin who can spin straw into gold. All that these modern-day, real-life alchemists are doing differently is using dairy and circuit boards rather than straw."

-via Good News Network, July 19, 2024

[mindblowingscience]

Scientists have created a 'living plastic' that self-destructs when the material begins to erode. In the composting process, the novel product breaks down within a month, compared with more traditional versions that take up to 55 days to decompose under the same conditions. The hopeful technology was inspired by the power of plastic-munching proteins, which are naturally produced by a species of bacteria discovered in 2016 at a recycling facility in Japan.

Continue Reading.

[randomalistic]

I think instead of outright rejecting all instances of AI, we instead need to critically think about What exactly we are gaining from using it and what experience we may be losing as a consequence

Use AI to do a bunch of painstakingly tedious scientific work for medical research? Valid use (ex. Protein folding software)

Use AI to summarize a the chapter of a book? Well I mean, you could. But what if you could’ve learned a new word? What if taking the time to immerse yourself helped you relax? What if reading the exact sentences as they were written by the author made you more emotionally invested?

and of course we’re pushed to strive for pure results because the US lives in a capitalist pressure cooker society obsessed with constant productivity and we are given less and less time to do things outside of work.

By using ai you might not even fathom what experiences are being robbed from you. Because 99% of the time, the process is the most valuable part of learning, never the final product.

I feel like this argument can be applied to all technology at this point, which is when it sort of becomes a slippery slope. But it’s undeniable that smartphones and social media have already consumed our social lives and made irl interaction less meaningful and less frequent. The best social interactions I’ve had were during a power outage, or other instances when I was ripped away from electronics. I’m not ready for AI to take away our sight of everything else. It terrifies me. But deep down I want to hope. I know that no matter how bad it might get in the future, we will rediscover ourselves time and time again. Humans have a certain tendency to break free

[girlactionfigure]

1 Nobel Prize in Chemistry - The Development of Multiscale Models for Complex Chemical Systems

2 Nobel Prize in Chemistry - Quasiperiodic Crystals

3 Nobel Prize in Chemistry - Decoding the Structure and The Function of The Ribosome

4 Nobel Prize in Economic Sciences - Repeated Games

5 Nobel Prize in Chemistry – Ubiquitin, Deciding the Fate of Defective Proteins in Living Cells

6 Nobel Prize in Economics - Human Judgment and Decision-Making Under Uncertainty

7 Fields Medal Award in Mathematics

8 Turing Award - Machine Reasoning Under Uncertainty

9 Turing Award - Nondeterministic Decision-Making

10 Turing Award - The Development of Interactive Zero-Knowledge Proofs

11 Turing Award - Developing New Tools for Systems Verification

12 Vine Seeds Discovered from The Byzantine Period

13 The World’s Most Ancient Hebrew Inscription

14 Ancient Golden Treasure Found at Foot of Temple Mount

15 Sniffphone - Mobile Disease Diagnostics

16 Discovering the Gene Responsible for Fingerprints Formation

17 Pillcam - For Diagnosing and Monitoring Diseases in The Digestive System

18 Technological Application of The Molecular Recognition and Assembly Mechanisms Behind Degenerative Disorders

19 Exelon – A Drug for The Treatment of Dementia

20 Azilect - Drug for Parkinson’s Disease

21 Nano Ghosts - A “Magic Bullet” For Fighting Cancer

22 Doxil (Caelyx) For Cancer Treatment

23 The Genetics of Hearing

24 Copaxone - Drug for The Treatment of Multiple Sclerosis

25 Preserving the Dead Sea Scrolls

26 Developing the Biotechnologies of Valuable Products from Red Marine Microalgae

27 A New Method for Recruiting Immune Cells to Fight Cancer

28 Study of Bacterial Mechanisms for Coping with Temperature Change

29 Steering with The Bats 30 Transmitting Voice Conversations Via the Internet

31 Rewalk – An Exoskeleton That Enables Paraplegics to Walk Again

32 Intelligent Computer Systems

33 Muon Detectors in The World's Largest Scientific Experiment

34 Renaissance Robot for Spine and Brain Surgery

35 Mobileye Accident Prevention System

36 Firewall for Computer Network Security

37 Waze – Outsmarting Traffic, Together

38 Diskonkey - USB Flash Drive

39 Venμs Environmental Research Satellite

40 Iron Dome – Rocket and Mortar Air Defense System

41 Gridon - Preventing Power Outages in High Voltage Grids

42 The First Israeli Nanosatellite

43 Intel's New Generation Processors

44 Electroink - The World’s First Electronic Ink for Commercial Printing

45 Development of A Commercial Membrane for Desalination

46 Developing Modern Wine from Vines of The Bible

47 New Varieties of Seedless Grapes

48 Long-Keeping Regular and Cherry Tomatoes

49 Adapting Citrus Cultivation to Desert Conditions

50 Rhopalaea Idoneta - A New Ascidian Species from The Gulf of Eilat

51 Life in The Dead Sea - Various Fungi Discovered in The Brine

52 Drip Technology - The Irrigation Method That Revolutionized Agriculture

53 Repair of Heart Tissues from Algae

54 Proof of The Existence of Imaginary Particles, Which Could Be Used in Quantum Computers

55 Flying in Peace with The Birds

56 Self-Organization of Bacteria Colonies Sheds Light on The Behaviour of Cancer Cells

57 The First Israeli Astronaut, Colonel Ilan Ramon

58 Dr. Chaim Weizmann - Scientist and Statesman, The First President of Israel, One of The Founders of The Modern Field of Biotechnology

59 Aaron Aaronsohn Botanist, Agronomist, Entrepreneur, Zionist Leader, and Head of The Nili Underground Organization

60 Albert Einstein - Founding Father of The Theory of Relativity, Co-Founder of the Hebrew University in Jerusalem

61 Maimonides - Doctor and Philosopher

Source

@TheMossadIL

[mariacallous]

Imitation caviar invented in the 1930s could provide the solution to plastic pollution, claims Pierre Paslier, CEO of London-based packaging company Notpla. He discovered the cheap food alternative, invented by Unilever and made using seaweed, after quitting his job as a packaging engineer at L’Oréal.

With cofounder and co-CEO Rodrigo García González, Paslier and Notpla have extended the idea, taking a protein made from seaweed and creating packaging for soft drinks, fast food, laundry detergent, and cosmetics, among other things. They’re also branching out into cutlery and paper.

“Seaweed grows quickly and needs no fresh water, land, or fertilizer,” Paslier explains. “It captures carbon and makes the surrounding waters less acidic. Some species of seaweed can grow up to a meter a day.” Best of all, he says, packaging made from seaweed is completely biodegradable because it’s entirely nature-based.

Paslier noted an amazing coincidence—Alexander Parkes invented the first plastic in Hackney Wick, the same part of East London that, 100 years later, Notpla calls home. Since Parkes’ first invention, waste plastic—especially tiny particles known as microplastics, which take hundreds or thousands of years to break down into harmless molecules—has been wreaking havoc in ecosystems across the world.

Plastic pollution is proving especially damaging in the marine environment, where tiny beads of plastic are deadly to the vital microorganisms that make up plankton and which sequester 30 percent of our carbon emissions, “without us having to build any new fancy technologies,” Paslier says.

Notpla’s plans to replace plastic began with a drink container for marathons. This is, in effect, a very large piece of fake caviar—a small pouch that contains juice or water that athletes can pop in their mouths and swallow when they need rehydration. “We wanted to create something that would feel more like fruit; packaging that you could feel comes more from picking something from a tree than off a production line,” he says.

Paslier showed pictures of two postrace streets—one where refueling came in plastic containers and one where it came in edible Notpla. The first was littered with plastic bottles; the second completely waste-free.

The next step was takeout food containers. Even containers we think are cardboard contain plastic, he says, as grease from food would make plain cardboard too soggy. Working with delivery company Just Eat, Notpla has pioneered a replacement for the per- and polyfluorinated substances (PFAS), the so-called “forever chemical” plastics that currently line cardboard takeout containers. It has even found a way to retrofit its solution into the old PFAS plant, so there was no need to build new factories.

The company is developing soluble sachets for detergent pods, ice-cream scoops, and even paper packing for cosmetics. And there’s plenty of seaweed to experiment with, Paslier points out. “You don’t realize it’s already available massively at scale,” he says. “It’s in our toothpaste, it’s in our beer, it’s in our reduced-fat products—so there’s an existing infrastructure that we can work with without having to build any additional processes.”

[awh-bowie]

⋆౨ৎ˚⟡˖ ࣪21 things i’ve learned since becoming an adult

˚ʚ♡ɞ˚ three years is not a terribly long time, but, i feel like regular metrics of time simply cannot be applied to girlhood and the transition to womanhood. my childhood felt like a single moment and being a teenager felt more like a century. but i digress, what have i learned in the three years since i became a legal adult?

୨୧ fostering meaningful friendships is far more important than any romantic relationship ୨୧

♡ the thing about romantic and physical relationships, especially when you’re young, is that they are not a reliable constant. all i can say about this is that close, trusted friends will benefit you better than any “situationship”.

୨୧ think of yourself like a plant, just a little bit more complex ୨୧

♡ what i mean by this is simple: if you feel awful for seemingly no reason, get some water, eat some fruit and go outside. more often than not, the mysterious specter making you sad is just yourself forgetting fundamental self-care!

୨୧ the best product for glowing skin is free! ୨୧

♡ drinking enough water is one of the easiest and most effective ways to maintain healthy skin. hydration helps flush out toxins, keeps your skin cells plump, and improves elasticity. scientifically speaking, staying hydrated supports your body’s natural detoxification processes!

୨୧ cry, cry, cry! ୨୧

♡ crying is a wonderful and natural way to release negative emotions, not something that is weak or embarrassing. we go into this life screaming and wailing, why stop now?

୨୧ invest in blue light glasses ୨୧

♡ blue light is the enemy of your eyes, especially looking at it in the dark. getting yellow-tinted glasses is a game changer, especially if you prefer low light! i never turn on my big light.

୨୧ you have boundaries, period. ୨୧

♡ there’s no such thing as not having boundaries. you can go through life without experiencing things you’d rather not experience again, these experiences create boundaries. if you genuinely can’t think of any boundaries, i suggest doing some journaling! here are some prompts i made for myself that really helped me.

୨୧ balance is good, but extremes aren’t evil ୨୧

♡ it’s okay to indulge, to be hedonistic! as long as you’re honoring yourself and the people in your life, go crazy every once and a while. that’s what life is about, diving into the things you love.

୨୧ use lighter concealer under your eyes ୨୧

♡ a lighter shade of concealer under your eyes helps brighten your face and hide dark circles!

୨୧ diet affects your skin and hair ୨୧

♡ proper nutrition plays a critical role in skin and hair health. consuming foods rich in vitamins and antioxidants, like fruits, vegetables, and lean proteins, can help prevent acne, improve hair growth, and promote a radiant complexion. see my post here to learn more ;3

୨୧ no one is looking at you, seriously, it’s biological ୨୧

♡ let me get a little sciency here. humans tend to overestimate how much people actually notice us, and this is something called the spotlight effect. it happens because our brains are wired to be super focused on ourselves, making us think everyone else is just as tuned in to us as we are. spoiler alert: they’re not. studies have shown that people pay way less attention to you than you think. realizing this is so freeing because once you know that your little slip-ups or bad hair days go unnoticed, you can start living with a lot less self-consciousness. embrace the freedom—no one is watching as closely as you imagine.

୨୧ independence isn’t loneliness ୨୧

♡ being independent doesn't mean you can’t ask for help or rely on others. sometimes the strongest thing you can do is reach out for support when you need it. true independence comes from knowing when to lean on others and when to stand on your own!

୨୧ dedicate time in your day to unplug ୨୧

♡ taking regular breaks from technology allows your brain to rest and recharge. studies indicate that unplugging can improve focus, reduce stress, and enhance well-being. scheduling time each day for a digital detox is beneficial for your mental health and productivity.

୨୧ you don’t have to justify the things you love ୨୧

♡ “i know it’s dumb but i really love [media] because it has my favorite actor in it!” STOP!! if you find yourself preemptively insulting your interest or explaining why you like it, stop and think. ask yourself what about the situation made you feel like you needed to do that.

୨୧ it’s okay to outgrow things ୨୧

♡ i wish i could stay a kid forever, but being an adult is kinda sick. drifting away from people, hobbies, media, etc… is a natural, unavoidable part of growing.

୨୧ it’s okay to not outgrow things ୨୧

♡ that being said, there’s nothing wrong with hanging onto the things that make you happy! if something you have from when you were a kid still brings joy to your life, it would be silly to give outgrowing it another thought. the fact that it still brings you joy means it cannot be outgrown.

୨୧ vitamin C for bright and even skin ୨୧

♡ vitamin C is a powerhouse for your skin!! it helps brighten your complexion, fade dark spots, and even out your skin tone by reducing melanin production. dermatologists recommend incorporating a vitamin C serum into your skincare routine to fight off free radicals and promote collagen production.

୨୧ being “busy” doesn’t equal being productive ୨୧

♡ it’s easy to confuse busyness with productivity. but being constantly busy doesn't mean you're getting more done. true productivity is about working smarter, not harder, and taking time to rest when needed.

୨୧ taking breaks IS productive ୨୧

♡ like i said, taking time to rest is key. studies show that regular breaks throughout the day, especially short ones, can improve concentration, reduce mental fatigue, and enhance performance!

୨୧ cold water rinse for shiny hair ୨୧

♡ a cold water rinse at the end of your shower can help seal your hair cuticles, resulting in shinier, smoother hair. cold water also helps reduce frizz and preserve hair’s natural oils.

୨୧ celebrate every victory ୨୧

♡ no win is too small! celebrating your successes, big or small, reinforces positive habits and boosts motivation. you deserve it, every day you exist is a victory in the eyes of others. according to psychologists, taking the time to acknowledge achievements can increase your sense of accomplishment and satisfaction.

୨୧ they say “trust your gut” for a reason! ୨୧

♡ your gut feeling, also known as intuition, is your brain’s way of quickly processing information based on past experiences and instincts. neuroscientists have found that gut instincts often come from subconscious pattern recognition, and trusting them can lead to better decision-making in situations where logic might not offer clear answers.

-Beau

[probablyasocialecologist]

The World Food Summit of 1996 approached food security through the principles of ensuring there is enough safe and nutritious food that can be accessed daily to meet healthy dietary needs and food preferences. By definition, this is a desirable and worthy goal. However, in the years since, food security has developed into a paradigm which does not question the underlying power dynamics and the reproduction of material conditions that make food insecurity a permanent feature of the global order. At its core, the food security paradigm deals only with access to food, without challenging the political and economic structures that determine and control access, as well as distribution.  By failing to address the root causes of hunger and famine, the food security paradigm makes it impossible to end hunger globally. Of course, many people worldwide possess food security, but this is restricted to increasingly limited geographic pockets. In terms of the people localised in one area, food vulnerability is influenced and determined by class, race, gender and, of course, citizenship status. Globally, “underdevelopment” and “de-development” lead to widespread food insecurity across areas. Another problem with the food security paradigm is that it is easily co-opted to generate partial answers that pose no threat to the corporate food system, or worse, that even open up new profit opportunities. Accelerated by other crises, the food security paradigm becomes ever more dependent on aid, be it through direct food delivery, cash transfers or small development projects that cannot compete with the food giants and their price-setting powers. In practice, a “science of food security” emerges, one which takes as its focus calories and the output that is compatible with precision agriculture having the aim to increase crop yields and to assist management decisions using high technology sensor and analysis tools. This model tends to be reliant on “Green Revolution” technologies that rely on chemical fertilisers and pesticides and that are tied to colonial projects and corporations, in order to optimise resources in aid response and/or development projects.  In this rationale, food insecurity can be addressed by reaching optimum yields of certain crops that should meet the demand for fats, fibres and protein. All of this is carefully managed and data-driven. Precision farming is advocated by the Alliance for a Green Revolution in Africa (AGRA) with the objective of optimising, “agricultural value chains […] critical in advancing food and nutrition sufficiency without increasing the size of land under cultivation.” The framing of food that reduces it only to “optimal input” relegates vital elements of food production and the culture of eating, like territory ownership, taste, heritage, care, well-being and connection as secondary. This reductionist approach has, though, proved useful to corporate agriculture, since it reinforces the case for genetically modified crops (GMOs), more efficient fertilisers, and the standardisation of food production for market purposes. Advocates of plant breeding technologies (including GMOs and hybrid seeds) argue that government overregulation is an obstacle to achieving food security. Overregulation, as the argument goes, denies populations the opportunity to grow crops that have increased nutrient use efficiency and are more resilient to climate shocks. 

[...]

The paradigm of food security is about optimising productivity. It’s true that productivity matters – after all, feeding the world requires enormous quantities of food. But if productivity is approached solely as a technological problem, it reinforces the tendency to fragment the quantitative and qualitative aspects of food production and consumption. On the quantitative side, production for food security is viewed as a challenge of multiplication. Whereas division, that is, distribution of food, is left to logistical planning. This ignores what Raj Patel identified in his influential 2007 book Stuffed and Starved, as the bottleneck of power that concentrates international food distribution among a small set of corporations. This bottleneck excludes the poor and small-scale food producers from decision-making. It also normalises worrying tendencies, such as an overreliance on industrial animal exploitation as a protein source, which has direct health implications, as well as longer term consequences like the proliferation of new viruses, greenhouse gas emissions and inefficient use of water and soil.

28 May 2024

[123567-9qaaq9]

Protein Expression Market to Witness Massive Growth Forecast to 2023-2033

Proteins, often referred to as the building blocks of life, are fundamental to nearly every biological process. From enzymes that catalyze biochemical reactions to signaling molecules that regulate cellular activities, proteins are indispensable. Protein expression is the process by which the genetic information encoded in DNA is translated into functional proteins within a cell.

The Global Protein Expression Market was valued at $2,393.0 million in 2023 and is expected to reach $6,963.6 million by 2033, growing at a CAGR of 11.27% between 2023 and 2033

Protein Expression Overview 

In the pharmaceutical and biotechnology industries, protein expression is a critical component of drug discovery and development. Recombinant proteins are used as therapeutic agents themselves, such as insulin for diabetes or monoclonal antibodies for cancer treatment. Additionally, proteins are utilized in the production of vaccines, diagnostics, and biologics manufacturing processes. The ability to express proteins with high yields, purity, and biological activity is paramount for ensuring the efficacy and safety of these products.

Market Segmentation

Segmentation 1: By Application

Segmentation 2: By End User 

Segmentation 3: By Product

Segmentation 4: By Expression System

Segmentation 5: By Region

Download our sample page now click here !

Applications Across the Scientific Landscape

The importance of protein expression transcends the boundaries of basic research, permeating diverse fields such as biotechnology, medicine, and industrial applications. In biopharmaceuticals, recombinant protein expression serves as the cornerstone of drug discovery and development, enabling the production of therapeutic proteins, antibodies, and vaccines.

Key Market Players 

Agilent Technologies, Inc.

Bio-Rad Laboratories, Inc.

Charles River Laboratories International, Inc.

Danaher Corporation (Abcam plc.)

GenCefe Co., Ltd.

Genscript Biotech Corporation

And many others 

Recombinant Protein Expression Market 

Recombinant protein expression is a testament to humanity's ingenuity in leveraging the natural machinery of cells to fulfill our scientific and commercial needs. At its core, the process involves introducing foreign DNA sequences – encoding the desired protein of interest – into host organisms such as bacteria, yeast, insect cells, or mammalian cells. Through the process of transcription and translation, these host cells become miniature protein factories, faithfully churning out the specified proteins with remarkable fidelity.

Visit our Life Sciences & Biopharma page for better understanding 

Gene Expression is the process by which the information encoded within our genes is converted into functional molecules – primarily proteins and non-coding RNAs – that carry out the myriad functions of living organisms. This process unfolds in two main stages: transcription and translation. During transcription, the DNA sequence of a gene is transcribed into a complementary messenger RNA (mRNA) molecule by the enzyme RNA polymerase.

In the dynamic landscape of biotechnology, protein production technologies play a pivotal role in unlocking the potential of proteins for a myriad of applications, ranging from therapeutics and diagnostics to industrial enzymes and biopolymers.

Recent Developments in the Protein Expression Market

•In January 2024, Evosep, a leader in sample preparation for mass spectrometry-based proteomics, partnered with Thermo Fisher Scientific Inc., a global scientific leader, to advance clinical proteomics research. This collaboration would combine Evosep's sample separation technology with Thermo Fisher Scientific Inc.'s mass spectrometry instruments, enhancing proteomics research capabilities. •In July 2023, Lonza Bioscience introduced the TheraPRO CHO Media System, a novel cell culture platform designed to streamline processes and enhance productivity and protein quality, particularly when used in conjunction with GS-CHO cell lines. This release would support pharmaceutical and biotechnology companies engaged in the manufacturing of therapeutic proteins, with the goal of improving product quality and expediting time-to-market.

Key Questions Answered 

Q What is the estimated global market size for the protein expression market?

Q What are the future trends expected in the protein expression market?

Q What does the supply chain and value chain of the protein expression market look like?

Q  What is the regulatory framework of the protein expression market?

Q How has the COVID-19 outbreak affected the future trajectory of the protein expression market?

Q What are the market entry barriers and opportunities in the protein expression market?

Q What are the major market drivers, challenges, and opportunities of the protein expression market?

Q How is each segment of the protein expression market expected to grow during the forecast period, and what is the anticipated revenue generated by each of the segments by the end of 2033?

Q What is the growth potential of the global protein expression market in North America, Europe, Asia-Pacific, Latin America, and Rest-of-the-World, and what are the driving and challenging factors of the market in each of these regions?

Q Who are the leading players with significant offerings in the protein expression market, and what is the current market dominance for each of these leading players? Who are the next frontiers in the protein expression market?

Conclusion 

Despite the significant advancements in protein expression technologies, several challenges persist, including the optimization of protein yields, the cost-effectiveness of production processes, and the scalability of manufacturing operations. Additionally, the complexity of mammalian expression systems poses challenges in terms of cell line development, process optimization, and regulatory compliance.

[beakers-and-telescopes]

Genetically Modified Bacteria Produce Energy From Wastewater

E. Coli is one of the most widely studied bacteria studied in academic research.  Though most people probably associate it with food/water borne illness, most strains of E. Coli are completely harmless.  They even occur naturally within your intestines.  Now, scientists at EPFL have engineered a strain of E. Coli that can generate electricity.

The survival of bacteria depends on redox reactions.  Bacteria use these reactions to interconvert chemicals in order to grow and metabolize.  Since bacteria are an inexhaustible natural resource, many bacterial reactions have been industrially implemented, both for creating or consuming chemical substrates.  For instance, you may have heard about researchers discovering bacteria that can break down and metabolize plastic, the benefits of which are obvious.  Some of these bacterial reactions are anabolic, which means that they need to be provided external energy in order to carry it out, but others are catabolic, which means that the reactions actually create energy.  

Some bacteria, such as Shewanella oneidensis, can create electricity as they metabolize.  This could be useful to a number of green applications, such as bioelectricity generation from organic substrates, reductive extracellular synthesis of valuable products such as nanoparticles and polymers, degradation of pollutants for bioremediation, and bioelectronic sensing.  However, electricity producing bacteria such as Shewanella oneidensis tend to be very specific.  They need strict conditions in order to survive, and they only produce electricity in the presence of certain chemicals.  

The method that Shewanella oneidensis uses to generate electricity is called extracellular electron transfer (EET).  This means that the cell uses a pathway of proteins and iron compounds called hemes to transfer an electron out of the cell.  Bacteria have an inner and outer cell membrane, so this pathway spans both of them, along with the periplasmic space between.  In the past, scientists have tried to engineer hardier bacteria such as E. Coli with this electron-generating ability.  It worked… a little bit.  They were only able to create a partial EET pathway, so the amount of electricity generated was fairly small.

Now, the EPFL researchers have managed to create a full pathway and triple the amount of electricity that E. Coli can produce.  "Instead of putting energy into the system to process organic waste, we are producing electricity while processing organic waste at the same time -- hitting two birds with one stone!" says Boghossian, a professor at EPFL. "We even tested our technology directly on wastewater that we collected from Les Brasseurs, a local brewery in Lausanne. The exotic electric microbes weren't even able to survive, whereas our bioengineered electric bacteria were able to flourish exponentially by feeding off this waste."

This development is still in the early stages, but it could have exciting implications both in wastewater processing and beyond.

"Our work is quite timely, as engineered bioelectric microbes are pushing the boundaries in more and more real-world applications" says Mouhib, the lead author of the manuscript. "We have set a new record compared to the previous state-of-the-art, which relied only on a partial pathway, and compared to the microbe that was used in one of the biggest papers recently published in the field. With all the current research efforts in the field, we are excited about the future of bioelectric bacteria, and can't wait for us and others to push this technology into new scales."

[acti-veg]

would everyone switching to being plant based cause ecological problems?

Plant-based diets require less land, less water, less energy, less deforestation and produce vastly lower greenhouse gas emissions. Even accounting for land that cannot be used for crops, we could comfortably feed far more people using far less resources if we were all eating plant-based. See my resource use page for an explanation on that, and the resources subpage for sources.

Keep in mind that there is no realistic scenario where this happens immediately, either. Current projections are based on current systems, but as the world transitions away from animal agriculture, we would make plant agriculture even more efficient, less damaging to soil and more sustainable. The farming of well-chosen crops directly is almost always going to be less ecologically damaging than farming animals, who require land to graze on and land to grow the vast vast quantities of crops they are fed.

All that said, there are problems that would be created through a switch to plant agriculture. Social erosion is one of them, considering how best to manage cropland so that we can re-wild less "productive" land, how we manage fertilisation and keeping out pests etc. But all of these issues are massive under our current system too, because again, farmed animals are fed vast quantities of soy, corn and wheat to get them to slaughter weight, and then you have to add on the vast tracts of (often arable, indigenous and/or deforested) land that they graze on.

Personally, I think that a plant-based agriculture system would need to include alternative proteins as well as arable crops. That could be in the form of fermented proteins which shows a lot of promise as an emerging technology, or possibly even lab grown meat if we can get rid of the animal input and make it more efficient, though I am much less convinced of that.

Either way, the overwhelming scientific consensus is that we could feed far more people, using far less land and fewer resources, if we started eating crops directly instead of feeding those crops to animals, then eating those animals. It is just an objectively more efficient way to feed our population.

[thediaryblog]

THE SUNDAY GUIDE!

🎀⭐️ pin: thediaryblog 

hii guys, this is guide to help you curate a day of relaxation, self-care, and setting the tone for the week: (remember, the key to a Sunday reset is to prioritize self-care, relaxation, and setting positive intentions for the week ahead.)

1. Morning Meditation and Stretching:

- Start your day with some gentle stretching or yoga to awaken your body and mind.

- Follow it up with a short meditation session to set positive intentions for the day.

Healthy Breakfast:

- Prepare a nourishing breakfast that will fuel your body and mind.

- Opt for whole foods like fruits, vegetables, whole grains, and proteins.

Declutter and Organize:

- Spend some time tidying up your living space. Decluttering can have a calming effect and help you feel more focused and organized. (plus who wouldn’t want to start their week with a clean room!)

Nature Walk or Outdoor Activity:

- Connect with nature by going for a walk in the park or spending time outdoors. (I’m so excited for the summer bc so nice to go outside and relax in the sun)

Skincare Routine:

- Treat your skin to some pampering with a skincare routine. Cleanse, exfoliate, and moisturize to keep your skin looking and feeling its best.

(you don’t have to have expensive products to have a Sunday reset)

Digital Detox:

- Take a break from screens and digital devices for a few hours. Disconnecting from technology can help you relax and recharge.

Self-Reflection and Planning:

- Set aside some time for self-reflection. Think about your goals, aspirations, and what you hope to achieve in the coming week.

Plan out your schedule and to-do list for the week ahead. Having a clear plan can help you feel more prepared and organized.

- d

[mindblowingscience]

While we often think of diseases as caused by foreign bodies—bacteria or viruses—there are hundreds of diseases affecting humans that result from errors in cellular production of proteins. A team of researchers led by the University of Massachusetts Amherst leveraged the power of cutting-edge technology, including an innovative technique called glycoproteomics, to unlock the carbohydrate-based code that governs how certain classes of proteins form themselves into the complex shapes necessary to keep us healthy. The research, published in the journal Molecular Cell, explores members of a family of proteins called serpins, which are implicated in a number of diseases. The research is the first to investigate how the location and composition of carbohydrates attached to the serpins ensure that they fold correctly. Serious diseases—ranging from emphysema and cystic fibrosis to Alzheimer's disease—can result when the cellular oversight of protein folding goes awry. Identifying the glyco-code responsible for high-fidelity folding and quality control could be a promising way for drug therapies to target many diseases.

Continue Reading.