#PrEP HIV

[anubisystem]

Last tweet mentions PrEP which is different from PEP — both are highly valuable, but rather than mitigate the risk of post-exposure contraction of hiv, PrEP is taken daily to prevent an HIV- person from contracting it from an HIV+ person, even if they have unprotected sex (or instances such as protected sex where a condom breaks or other common suboptimal things happen). It’s a preventive prophylactic sort of like a birth control pill (in that you take it every day and it prevents a serious health complication). It stands for Pre-Exposure Prophylaxis, as in prevention. I’m on it—planned parenthood prescribes it, lgbtq centers typically have outreach and/or prescription services about it, and if you have a pcp it may be worth asking for one. (Also, at your earliest convenience, get your monkey pox vaccine. One of my favorite flexes is that I was one of the first people in the USA to get it, back in August 2022.)

The year is 2023 and transmission of HIV is completely preventable. Community health is something all of us contribute to - take care of yourself, and of all of us!

[fidicushiv]

Call : +917997101303 | Whatsapp : https://wa.me/917997101505 | Website : https://fidicus.com

ఎక్కువ మందితో ప్రొటెక్షన్ లేకుండా కలుస్తున్నారా? Unprotected Sex | HIV AIDS PrEp Treatment Cure

Stay protected from HIV infection even when engaging in sex with multiple unknown partners by using PrEP (Pre-Exposure Prophylaxis) treatment. This YouTube video explains how PrEP effectively reduces the risk of HIV transmission when taken consistently. Learn about the importance of regular medical consultations, proper condom use, and adherence to the medication. Stay informed and safeguard your health with these essential prevention strategies.

Dr. Bharadwaz | HIV AIDS | Health & Fitness | Homeopathy, Medicine & Surgery | Clinical Research

#PrEP #HIVPrevention #SafeSex #SexualHealth #hivawareness

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Specialty Clinic Fidicus HIV highest success with homeopathy Improve Wellness | Increase Longevity | Addresses Questions

[reasonsforhope]

"A large clinical trial in South Africa and Uganda has shown that a twice-yearly injection of a new pre-exposure prophylaxis drug gives young women total protection from HIV infection.

The trial tested whether the six-month injection of lenacapavir would provide better protection against HIV infection than two other drugs, both daily pills. All three medications are pre-exposure prophylaxis (or PrEP) drugs.

Physician-scientist Linda-Gail Bekker, principal investigator for the South African part of the study, tells Nadine Dreyer what makes this breakthough so significant and what to expect next.

Tell us about the trial and what it set out to achieve

The Purpose 1 trial with 5,000 participants took place at three sites in Uganda and 25 sites in South Africa to test the efficacy of lenacapavir and two other drugs.

Lenacapavir (Len LA) is a fusion capside inhibitor. It interferes with the HIV capsid, a protein shell that protects HIV’s genetic material and enzymes needed for replication. It is administered just under the skin, once every six months.

The randomised controlled trial, sponsored by the drug developers Gilead Sciences, tested several things.

The first was whether a six-monthly injection of lenacapavir was safe and would provide better protection against HIV infection as PrEP for women between the ages of 16 and 25 years than Truvada F/TDF, a daily PrEP pill in wide use that has been available for more than a decade.

Secondly, the trial also tested whether Descovy F/TAF, a newer daily pill, was as effective as F/TDF...

The trial had three arms. Young women were randomly assigned to one of the arms in a 2:2:1 ratio (Len LA: F/TAF oral: F/TDF oral) in a double blinded fashion. This means neither the participants nor the researchers knew which treatment participants were receiving until the clinical trial was over.

In eastern and southern Africa, young women are the population who bear the brunt of new HIV infections. They also find a daily PrEP regimen challenging to maintain, for a number of social and structural reasons.

During the randomised phase of the trial none of the 2,134 women who received lenacapavir contracted HIV. There was 100 percent efficiency.

By comparison, 16 of the 1,068 women (or 1.5%) who took Truvada (F/TDF) and 39 of 2,136 (1.8%) who received Descovy (F/TAF) contracted the HIV virus...

What is the significance of these trials?

This breakthrough gives great hope that we have a proven, highly effective prevention tool to protect people from HIV.

There were 1.3 million new HIV infections globally in the past year. Although that’s fewer than the 2 million infections seen in 2010, it is clear that at this rate we are not going to meet the HIV new infection target that UNAIDS set for 2025 (fewer than 500,000 globally) or potentially even the goal to end Aids by 2030...

For young people, the daily decision to take a pill or use a condom or take a pill at the time of sexual intercourse can be very challenging.

HIV scientists and activists hope that young people may find that having to make this ��prevention decision” only twice a year may reduce unpredictability and barriers.

For a young woman who struggles to get to an appointment at a clinic in a town or who can’t keep pills without facing stigma or violence, an injection just twice a year is the option that could keep her free of HIV.

What happens now?

The plan is that the Purpose 1 trial will go on but now in an “open label” phase. This means that study participants will be “unblinded”: they will be told whether they have been in the “injectable” or oral TDF or oral TAF groups.

They will be offered the choice of PrEP they would prefer as the trial continues.

A sister trial is also under way: Purpose 2 is being conducted in a number of regions including some sites in Africa among cisgender men, and transgender and nonbinary people who have sex with men.

It’s important to conduct trials among different groups because we have seen differences in effectiveness. Whether the sex is anal or vaginal is important and may have an impact on effectiveness.

How long until the drug is rolled out?

We have read in a Gilead Sciences press statement that within the next couple of months [from July 2024] the company will submit the dossier with all the results to a number of country regulators, particularly the Ugandan and South African regulators.

The World Health Organization will also review the data and may issue recommendations.

We hope then that this new drug will be adopted into WHO and country guidelines.

We also hope we may begin to see the drug being tested in more studies to understand better how to incorporate it into real world settings.

Price is a critical factor to ensure access and distribution in the public sector where it is badly needed.

Gilead Sciences has said it will offer licences to companies that make generic drugs, which is another critical way to get prices down.

In an ideal world, governments will be able to purchase this affordably and it will be offered to all who want it and need protection against HIV."

-via The Conversation, July 3, 2024

[osokasstuff]

in relation to the last reblog, some things about HIV. (it's not really a proper educational post (tm) just some facts and misconceptions that i wanna bring so please do your own research if you're able).

HIV is transmitted through blood and sex.

HIV is NOT transmitted through air, saliva, common dishes, household items, etc.

PrEP = pre-exposure prophylaxis. treatment that you get if you regularly participate in risky activities to prevent getting HIV. if you regularly participate in risky activities (share syringes with someone, have unprotected sex), you may consider using PrEP. YOU NEED TO BE HIV- TO USE PrEP!! usage of PrEP if you've already got HIV is dangerous! HIV may develop resistance to the anti-retroviral drug you intake for PrEP, and it can make treatment more difficult!

PEP = post-exposure prophylaxis. treatment that you get as an emergency if you get at risk suddenly (had unprotected sex with someone whose status you don't know, were sexually assaulted, don't remember whether you used condoms or not, condom slipped/teared, shared syringe with someone, etc). it is an EMERGENCY MEASURE that couldn't be used on a regular basis. if you're exposed at risk on a regular basis, consider using PrEP.

PEP needs to be started NO LATER THAN IN 72 HOURS after exposure. the earlier you start, the higher the effectiveness is.

what does it mean: after exposure, you'll have HOURS to contact with medical provider/center/place where you can get PEP and start treatment. so it's better to research opportunities beforehand. maybe get a supply, if it's legal. but at least you need to find a place where to go in emergency case.

the most risky activities are: usage of same syringe for injections, unprotected sex with contact of genitalia and anal, sexual assault (PEP is recommended). consencual oral sex has very very very low risks (PEP is not recommended). anyways, if you think you have been exposed at risk, you should contact your medical provider or centers that specialize in HIV prophylaxis and treatment. it's better to contact in any doubts.

idk how it works in other countries, but where i live we have (some) HIV/AIDS centers where people can get tested, get PrEP, PEP, and help with access to antiretroviral treatment. places that you can research: HIV/AIDS centers, planned parenthood, reproductive clinics, queer-specialized places, etc.

HIV IS NOT ADDICTS-ONLY DISEASE. HIV IS NOT QUEER-ONLY DISEASE. HIV IS NOT MARGINALIZED PEOPLE-ONLY DISEASE. marginalized groups have their risks because of stigma, ostracization, medical neglect, etc. BUT no one is immune to HIV. A LOT OF, and i mean it, generally privileged people get and transmit HIV because they're sure they will never get it.

there are MORE THAN ONE HIV STRAIN. and you can get more than one HIV strain. so if you're living with HIV and going to have risky activity with someone living with HIV and you've not gotten it one from another, YOU STILL NEED PROTECTION. (if you both don't have undetectable viral load).

UNDETECTABLE = UNTRANSMITTABLE. if someone lives with HIV and has undetectable viral load, they can't transmit HIV to someone else. which means you can have unprotected sex with them (if you all don't have other STDs), they can give birth and don't transmit HIV to the children, etc.

HIV IS NOT THE ONLY STD. there are others, and their transmission differs from HIV transmission. for example, oral sex is risky for gonorrhea. so DON'T NEGLECT CONDOMS!

HIV and STDs are not the worst things in the world. most STDs are either curable or controllable, and you can live fine with them. and anyways, no disease should be stigmatized.

HIV and STDs aren't dirty. thinking that "only dirty shameless people can get HIV/STD" is a) discriminatory; b) factually incorrect - everyone can get STDs; c) prevents people from getting tests and treatment; d) promotes the spread and evolution of STDs.

anti-retroviral therapy may be expensive/inaccessible in lots of places. research the situation where you live and your opportunities in case you'll need HIV-associated treatment (PrEP, PEP, anti-retroviral treatment).

people who know that they have HIV are not the "dangerous" ones. the "dangerous" ones are people who have never gotten tested, who are sure that HIV is not something that they can get, and who ask you to have a sex without a condom.

i'm sorry if i say obvious things here, but i'm not sure about public awareness around HIV and thought that if someone can be surprised that person living with HIV can have children without HIV, then these things should be articulated.

[bibleofficial]

i hate this country so fucking much ‘show up at 8 & u can get ur mpox vaccine before ur bloods :)’ & i show up at 8 & everything is fucking closed bro im straight up about to walk back home without even waiting to do bloods this is fucking stupid i hate my LIFEEEEEEE

[creepyscritches]

Formulating a high level question on the financial side of medicine when my strength lies in clinical and only hearing crickets in the call when I finish like.......am I loudly stupid or does no one have an answer

[jcsmicasereports]

POFF SHOOTS OF PrEP ( Pre Exposure Prophylaxis for HIV) Clinics by Saraswathi Lakkasani MD in Journal of Clinical Case Reports Medical Images and Health Sciences

Introduction

HIV preexposure prophylaxis (PrEP), is use of antiretroviral medications to prevent acquisition of HIV infection, in a HIV negative person who has on going risk of acquiring HIV. This strategy has proven effective in several recently published reports. The regimen if used optimally has HIV reduction record of 99%. However, there are several positive unforeseen benefits in this strategy. In this observational study we are presenting some additional benefits we observed in our Prep Clinic.

We are reporting the findings of our on-going PrEP Clinic for your perusal. Saint Michaels Medical Center is a 150 to 200 bedded community hospital, at Newark, New Jersey. We follow more than 200 PrEP clients in our Prep Clinic. We follow the state mandated protocol for induction and follow up.

Observation Results

So far there is no seroconversion to HIV after starting PrEP. Two of our clients had successful full term, normal pregnancies with sero negative healthy babies. Statistically significant number of STI’s (sexually transmitted Infections) were diagnosed and successfully treated and Significant number of unimmunized clients for Hepatitis B and A were identified and immunized. One case of uncontrolled diabetes and one hypercalcemia were identified at the initial visit and referred to the respective specialist. One patient was found to have anal mass, six months into the program, being pursued by colorectal surgeon.

Conclusion

Among the risk groups benefited by PrEP, the use of PrEP has increased by 500%. The average age group of clients falls between 25 to 35 who are in good health and with very few comorbidities who may or may not come to Primary care clinics on regular basis.

PrEP clinics gives an excellent opportunity to detect, diagnose and treat some of the commonly missed but treatable medical issues. The demand will be increasing in future. Our findings may be the tip of an iceberg.

[batsarebetterthanpeople]

""I'm sorry ma'am but it needs to go through a specialty pharmacy"" it is not that hard I just want my bespoke faggot meds so I don't get AIDS goddamn

[fxmmeangel]

twitter keeps showing me posts about how people who take prep are whores?? and like getting aids/hiv is some morally reprehensible act that means you’re awful?? what is wrong with yall 😻

[gwydionmisha]

This is something 1988 me couldn't imagine. We've made so much progress.

[vulpine111]

I'm glad I have enough spoons to make phone calls today.

I called the clinic that might help me get on PrEP. I will be seen in late December. I look forward to being on medication that will prevent me from catching HIV, even if that means lots of blood work.

I gotta call back the clinic that managed my testosterone next, but I also just called insurance for a ride to see my sleep specialist next Thursday. I'm going to try to get a CPAP mask that won't blow air into my eyes or give me as many sensory issues.

I also initiated the process to get a different care coordinator- one that might actually get me the level of support I require.

While I am at it, maybe I should finally look for a nutritionist who can help me lose some more weight. I'll try the UNM Truman Clinic. My goal weight for the hysterectomy is now 235 pounds but I'd like to get down to about 200.

My goal weight before I get top surgery would be even less, but we will see what is realistic.

I like to eat, after all.

[frameacloud]

Brittney McNamara (December 5, 2016). "What to Do If You've Been Exposed to HIV." Teen Vogue.

The more people who know about what to do in that situation, the better.

[puppy-darling]

BTW PrEP is pretty easy to get on in most US states, the most annoying thing about it is that you have to get tested monthly-ish, but also you should be getting tested anyway. All the hot gays are on PrEP. It reduces your chance of acquiring HIV from sex by NINETY NINE PERCENT.

You never know if condoms will tear! Many people don't know their HIV status! You can get HIV from oral sex on any type of genitalia!

ONE pill a day!

Be PrEPared!

[puppyvomits]

Navigating HIV in the age of Sniffies and PREP.

I am HIV neutral. This is a term coined by DogBoiBailey to designate people like us: those living with HIV who are on treatment and undetectable. People who are living with HIV who are on medication and undetectable neutralize the virus' effects on our bodies and are unable to transmit the virus. I have been living with HIV since 2021 and have often discussed that despite my transparency with my status, that I do not believe that any person living with HIV owes disclosure of their status to others at the beginning of an interaction or when you show interest in them. This belief has often times been met with pushback from community members who believe that it is irresponsible to say that people with HIV should have a choice in whether they disclose their status to others. I also recognize that certain states have laws that require disclosure and yet despite this, I assert my belief that upfront disclosure is not owed to anyone. Disclosure laws are rooted in the historic homophobia and stigma that is associated with HIV/AIDS in the United States and was often times used as a means of weaponizing the criminal justice system against marginalized communities who were deemed as "dirty" and "suffering the repercussions of being men who sleep with men". It forced HIV patients in the 80s out to employers in a time where there were no laws protecting people from being fired for their HIV status or sexual orientation. Even today, people who argue that people living with HIV owe others disclosure ignore the very real stigmas associated with HIV and ignore that not all states, cities, and communities accept or treat people living with HIV with understanding or acceptance. On hookup apps, we often see bios that boldly demand you "Be clean" or "disease free". There are tattoo artists who refuse to tattoo people with HIV. Prisons have refused HIV neutral individuals access to their antiviral medications, causing them to fall ill and die. Your perceived fear of infection does not take seniority to people's safety. The reality is, we are all in charge of our own sexual health. It is not a person living with HIV's responsibility to disclose their status upfront when your express interest in them, it is also your responsibility to foster a conversation that promotes healthy sexual practices for all parties involved. It is everyone's responsibility to lead with kindness, understanding, and the knowledge that we must take the necessary steps to ensure our own wellbeing in sexual encounters especially when we are engaging in these encounters with strangers. We must have the empathy to understand that not everyone can share their status on their profiles. Undetectable means untransmittable. As a person living with HIV, I take care of my health because I love myself and I love my community enough to stop the spread of HIV. I urge other people in our community to do the same by getting on PREP if they're negative and by getting undetectable if they are positive. Don't reward those people with cruelty and make demands of them when you could take the steps to ensure your safety regardless of another persons status.