#CoronaVirus effect

[iliveinprocrasti-nationn]

fauci saying “vulnerable people will fall by the wayside” and that some will die but that’s ok because we’re not going to see the “tsunami of cases” we’ve seen before is so dehumanising. so babies with no immune system, elderly people, disabled people, and people without adequate access to healthcare can all die of covid. but it’s ok guys because actually they’re just falling to the wayside and everyone else will go back to normal and be fine (sarcasm).

my death or the deaths of my family or friends wouldn’t be us “falling by the wayside”, it would be us being failed by our government, healthcare systems, and communities who have refused to take coronavirus seriously despite mounting anecdotal and scientific evidence of the harm this virus does. fact that people can accept the deaths of vulnerable groups just because they want to eat in a restaurant or don’t want to wear a mask is horrifying

[crimeronan]

i AM very excited to get my COVID shot with a system that's now pumped up with hydroxychloroquine. i've barely reacted to any of my prior shots (save a very sore arm) and when i got the actual coronavirus i was so horrifically ill and contagious that i almost 100% wouldve ended up in the hospital without paxlovid. even WITH paxlovid i was Fucking Miserable. if this shot makes me sick as a dog the way that people promise it will THEN THAT MEANS MY BODY IS FINALLY BECOMING HEALTHY AS FUCK....

[tomorrowusa]

« [I]f you’re willing to support the election of a president who cannot conceive of any distinction between what he wants and what the law permits, you are placing the survival of the Republic at risk. »

— Jonathan Chait at New York Magazine (archived).

The burden is on us to go the extra mile in this election to preserve democracy. Part of that is to highlight Trump's most disastrous failure.

If you know anybody afflicted by Trumpnesia, the burden is on you to address that condition. It's necessary to speak up now and do so assertively.

Some people have forgotten how Trump's mishandling of the COVID-19 emergency tanked the economy. There was the Trump COVID recession, the HŪGE spike in unemployment, and the supply chain issues and need to heavily stimulate spending to prevent another Great Depression which drove inflation for a couple of years.

COVID-19 was an international crisis. But some countries handled it much better than others. Under Trump, the US had the worst per capita death rate of all the G-7 countries.

The Trump White House was actually giving out quack medical advice such as recommending that people take Hydroxychloroquine – an anti-malaria drug which also acts as an immunosuppressant. The last thing you need when fighting an infection is an immunosuppressant. Trump also recommended that Americans drink bleach.

Reminding people in the next week or two of how catastrophic the last year of the Trump administration was may be the best way to preserve American democracy.

Millions Have Amnesia About the Worst of Trump’s Presidency. Memory Experts Explain Why. How Trump is benefiting from the limits of our memory.

[legacysam]

so far having covid is like. a bad cold + bonus anxiety about how bad it could get and I do not like it one bit

[corona-journal]

....huh?

Being afflicted with a chronic condition, akin to early stages of dementia, has a "silver lining"?

I think that the writer of that line shows their own wish to be detached, and slightly envious (in the moment) of others not being fully aware....

Having spoken to a few people with 'covid fog' it's frustrating for them as they reach for a word or try to put a concept together because the words aren't coming out right, or being interpreted the right way...

They know what they want to say, there is a muddled language part of the brain now.

If there's ever a silver lining to a chronic condition, please let me know, because I can't think of one....

21 December 2022

x

[thoughtportal]

Opinion Here’s how to get free Paxlovid as many times as you need it

When the public health emergency around covid-19 ended, vaccines and treatments became commercial products, meaning companies could charge for them as they do other pharmaceuticals. Paxlovid, the highly effective antiviral pill that can prevent covid from becoming severe, now has a list price of nearly $1,400 for a five-day treatment course.

Thanks to an innovative agreement between the Biden administration and the drug’s manufacturer, Pfizer, Americans can still access the medication free or at very low cost through a program called Paxcess. The problem is that too few people — including pharmacists — are aware of it.

I learned of Paxcess only after readers wrote that pharmacies were charging them hundreds of dollars — or even the full list price — to fill their Paxlovid prescription. This shouldn’t be happening. A representative from Pfizer, which runs the program, explained to me that patients on Medicare and Medicaid or who are uninsured should get free Paxlovid. They need to sign up by going to paxlovid.iassist.com or by calling 877-219-7225. “We wanted to make enrollment as easy and as quick as possible,” the representative said.

Indeed, the process is straightforward. I clicked through the web form myself, and there are only three sets of information required. Patients first enter their name, date of birth and address. They then input their prescriber’s name and address and select their insurance type.

All this should take less than five minutes and can be done at home or at the pharmacy. A physician or pharmacist can fill it out on behalf of the patient, too. Importantly, this form does not ask for medical history, proof of a positive coronavirus test, income verification, citizenship status or other potentially sensitive and time-consuming information.

But there is one key requirement people need to be aware of: Patients must have a prescription for Paxlovid to start the enrollment process. It is not possible to pre-enroll. (Though, in a sense, people on Medicare or Medicaid are already pre-enrolled.)

Once the questionnaire is complete, the website generates a voucher within seconds. People can print it or email it themselves, and then they can exchange it for a free course of Paxlovid at most pharmacies.

Pfizer’s representative tells me that more than 57,000 pharmacies are contracted to participate in this program, including major chain drugstores such as CVS and Walgreens and large retail chains such as Walmart, Kroger and Costco. For those unable to go in person, a mail-order option is available, too.

The program works a little differently for patients with commercial insurance. Some insurance plans already cover Paxlovid without a co-pay. Anyone who is told there will be a charge should sign up for Paxcess, which would further bring down their co-pay and might even cover the entire cost.

Several readers have attested that Paxcess’s process was fast and seamless. I was also glad to learn that there is basically no limit to the number of times someone could use it. A person who contracts the coronavirus three times in a year could access Paxlovid free or at low cost each time.

Unfortunately, readers informed me of one major glitch: Though the Paxcess voucher is honored when presented, some pharmacies are not offering the program proactively. As a result, many patients are still being charged high co-pays even if they could have gotten the medication at no cost.

This is incredibly frustrating. However, after interviewing multiple people involved in the process, including representatives of major pharmacy chains and Biden administration officials, I believe everyone is sincere in trying to make things right. As we saw in the early days of the coronavirus vaccine rollout, it’s hard to get a new program off the ground. Policies that look good on paper run into multiple barriers during implementation.

Those involved are actively identifying and addressing these problems. For instance, a Walgreens representative explained to me that in addition to educating pharmacists and pharmacy techs about the program, the company learned it also had to make system changes to account for a different workflow. Normally, when pharmacists process a prescription, they inform patients of the co-pay and dispense the medication. But with Paxlovid, the system needs to stop them if there is a co-pay, so they can prompt patients to sign up for Paxcess.

Here is where patients and consumers must take a proactive role. That might not feel fair; after all, if someone is ill, people expect that the system will work to help them. But that’s not our reality. While pharmacies work to fix their system glitches, patients need to be their own best advocates. That means signing up for Paxcess as soon as they receive a Paxlovid prescription and helping spread the word so that others can get the antiviral at little or no cost, too.

{source}

[jcmarchi]

Artificial mucus identifies link to tumor formation - Technology Org

New Post has been published on https://thedigitalinsider.com/artificial-mucus-identifies-link-to-tumor-formation-technology-org/

Artificial mucus identifies link to tumor formation - Technology Org

Excess mucus is a common, unpleasant symptom of illness during cold and flu season, but the slippery substance is essential to human health. To better understand its many roles, researchers synthesized the major component of mucus, the sugar-coated proteins called mucins. They discovered that changing the mucins of healthy cells to resemble those of cancer cells made healthy cells act more cancer-like.

[embedded content]

The researcher will present her results today at the American Chemical Society (ACS) spring meeting. ACS Spring 2024 is a hybrid meeting held virtually and in person March 17-21; it features nearly 12,000 presentations on a range of science topics.

“For hundreds of years, mucus was considered a waste material or just a simple barrier,” says Jessica Kramer, a professor of biomedical engineering who led the study. And indeed, it does serve as a barrier, regulating the transport of small molecules and particulates to underlying epithelial cells that line the respiratory and digestive tracts. But it also does much more. Studies show that mucus and mucins are biologically active, playing roles in immunity, cell behavior and defense against pathogens and cancer. Kramer’s team at the University of Utah, for example, recently found that specific sugars attached to mucins inhibited coronavirus infection in cell culture.

“Part of the challenge of studying mucus and mucins in general is that they have quite a variety of protein structures,” Kramer explains. Although humans share more than 20 mucin genes, those genes are expressed differently in different tissues and are spliced to generate a range of proteins. In addition, cells modify those proteins in myriad ways with different sugars to meet the body’s needs.

Complicating the picture, genetic factors alone don’t determine mucin composition. Dietary and environmental factors can also influence which sugars become attached to these proteins. Thus, mucus composition can vary significantly from person to person, from day to day, and from tissue to tissue, all of which makes it difficult to identify the biological effects of any given mucin.

To study mucin properties, researchers can collect mucus from slaughterhouse animals, Kramer says. “But ultimately, it’s quite labor intensive and difficult to purify. And in the harvesting process, the sticky, slimy properties are usually disrupted.”

Synthetic mucus is revealing how the slimy substance impacts human health and disease, including protection against infection and cancer. Image credit: Jessica Kramer

As an alternative, mucins can be purchased off-the-shelf, Kramer explains. But because batch-to-batch variability can lead to problems with experimental reproducibility, methods are needed to reliably produce synthetic mucins at scale and at a reasonable price.

In the absence of a simple genetic method to produce individual mucins, Kramer’s lab combined synthetic chemistry and bacterial enzymes to generate the core polypeptides and then selectively add sugars to create unique synthetic mucins. This allows the researchers to test the physical, chemical and biological properties of individual types of mucin molecules and identify the impact of changing individual sugars or protein sequences.

Kramer, along with the lab of collaborator Jody Rosenblatt at King’s College London, is applying her team’s mucins to questions of cancer biology. In particular, the scientists are exploring the influence of mucins on the earliest stages of tumor formation. Previous studies in other labs have shown that mucins embedded in the surface of cancer cells promote metastasis, the spread of cancer to other tissues in the body. These mucins can also help the cancer cells evade immune system defenses by blocking immune cell activation.

“We are building synthetic mucins to understand how the chemical aspects of these proteins affect the behavior of cancer cells,” Kramer explains. “It hasn’t been possible to study these things before because we can’t control the molecular properties of mucins using traditional genetic and biochemical methods.”

Normally, as non-cancerous epithelial cells grow, they crowd together, with some getting eliminated from the epithelial layer to maintain a consistent and stable tissue structure. When Kramer’s team engineered the cells to have a bulky mucin-rich surface similar to that of cancer cells, the cells stopped extruding normally and piled up, forming what looked like the start of tumors.

Kramer is quick to note, however, that her team has not determined whether the genetics of the cells have changed, so they cannot yet state definitively whether the healthy cells were transformed into cancer cells. Those studies are ongoing.

The insights will be pivotal for the development of possible cancer treatments targeting mucins, as they will help highlight which parts of the mucin molecules are most important to tumor formation.

[embedded content]

Scientists have been trying to make mucin-targeting therapeutics for decades, but that hasn’t worked well, in part because the sugar groups on the molecules weren’t fully taken into account, Kramer says. “For a vaccine, we can’t only consider the protein sequence because that’s not what the molecule looks like to the immune system. Instead, when an immune cell bumps into the surface of a cancer cell it’s going to see the sugars first, not the protein backbone.” So she believes an effective vaccine will need to target those mucin sugars.

Beyond cancer, the ability to reliably modify the protein sequence and sugars and produce scalable quantities of synthetic mucins offers opportunities to develop these molecules as anti-infectives, probiotics and therapies to support reproductive and women’s health, Kramer says.

Source: acs.org

You can offer your link to a page which is relevant to the topic of this post.

[crisismonitor]

Ο Covid σκότωσε 7 εκατ. ανθρώπους - Πόσοι περιμένουν τη «Νόσο Χ»

Πριν από ακριβώς τέσσερα χρόνια, στις 11 Μαρτίου του 2020, ο Παγκόσμιος Οργανισμός Υγείας κήρυξε τον Covid-19 πανδημία. Πάνω από 7 εκατομμύρια άνθρωποι φέρεται να έχουν πεθάνει από τη νόσο έως τις 25 Φεβρουαρίου 2024, σύμφωνα με τα επίσημα στοιχεία του οργανισμού. Continue reading Ο Covid σκότωσε 7 εκατ. ανθρώπους – Πόσοι περιμένουν τη «Νόσο Χ»

[agronayurveda]

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#coronavirus#coronavirus#awareness#stayhome

[rozzyblogs]

i love self care and hygiene products and feeling like i’m doing something with myself and treating myself well, because i used to try and do the opposite.

i think this is especially important growing up on social media, especially because of covid, because we were all locked up in our houses and telling each other online about how we wanted to kill ourselves, and we were all so desperate to be worse than each other that we stopped doing things we should’ve been doing. when i was 13, i never washed my face and i wore day-old makeup and i was too unmotivated to brush my teeth. i didn’t dress my wounds. i didn’t care about being comfortable, i cared about survival.

and now things are so very different. and not always in a good way; i still struggle with hurting myself. nowadays it is less about blades and more about empty plates. but things are different, and i care about being comfortable. i drink lots of water. i don’t have energy drinks, because i care now about the anxiety and paranoia the caffeine gives me. i eat fruit (if only easy-peeler oranges) and i don’t stay up until 4 AM every night, because i care.

and i think that’s so hard to admit when you’ve come from an environment where you’re all desperately trying to prove you’re worse than each other. hey, i used a scented soap and the new bath salts i was gifted. hey, i’m sitting in my bed and thinking about how i’m going to go to sleep later at a reasonable time, because i want to wake up in the morning. thats a hard thing to say! that’s a terrifying thing to say!!

i think it is so important for us to tell people. i think it is so important for us to remind each other that we do not want to be worse, we want to be better. i want to wake up in the morning. i care.

[reasonsforhope]

Article | Paywall Free

"The Food and Drug Administration approved new mRNA coronavirus vaccines Thursday [August 22, 2024], clearing the way for shots manufactured by Pfizer-BioNTech and Moderna to start hitting pharmacy shelves and doctor’s offices within a week.

Health officials encourage annual vaccination against the coronavirus, similar to yearly flu shots. Everyone 6 months and older should receive a new vaccine, the Centers for Disease Control and Prevention recommends.

The FDA has yet to approve an updated vaccine from Novavax, which uses a more conventional vaccine development method but has faced financial challenges.

Our scientific understanding of coronavirus vaccines has evolved since they debuted in late 2020. Here’s what to know about the new vaccines.

Why are there new vaccines?

The coronavirus keeps evolving to overcome our immune defenses, and the shield offered by vaccines weakens over time. That’s why federal health officials want people to get an annual updated coronavirus vaccine designed to target the latest variants. They approve them for release in late summer or early fall to coincide with flu shots that Americans are already used to getting.

The underlying vaccine technology and manufacturing process are the same, but components change to account for how the virus morphs. The new vaccines target the KP.2 variant because most recent covid cases are caused by that strain or closely related ones...

Do the vaccines prevent infection?

You probably know by now that vaccinated people can still get covid. But the shots do offer some protection against infection, just not the kind of protection you get from highly effective vaccines for other diseases such as measles.

The 2023-2024 vaccine provided 54 percent increased protection against symptomatic covid infections, according to a CDC study of people who tested for the coronavirus at pharmacies during the first four months after that year’s shot was released...

A nasal vaccine could be better at stopping infections outright by increasing immunity where they take hold, and one is being studied in a trial sponsored by the National Institutes of Health.

If you really want to dodge covid, don’t rely on the vaccine alone and take other precautions such as masking or avoiding crowds...

Do the vaccines help prevent transmission?

You may remember from early coverage of coronavirus vaccines that it was unclear whether shots would reduce transmission. Now, scientists say the answer is yes — even if you’re actively shedding virus.

That’s because the vaccine creates antibodies that reduce the amount of virus entering your cells, limiting how much the virus can replicate and make you even sicker. When vaccination prevents symptoms such as coughing and sneezing, people expel fewer respiratory droplets carrying the virus. When it reduces the viral load in an infected person, people become less contagious.

That’s why Peter Hotez, a physician and co-director of the Texas Children’s Hospital Center for Vaccine Development, said he feels more comfortable in a crowded medical conference, where attendees are probably up to date on their vaccines, than in a crowded airport.

“By having so many vaccinated people, it’s decreasing the number of days you are shedding virus if you get a breakthrough infection, and it decreases the amount of virus you are shedding,” Hotez said.

Do vaccines prevent long covid?

While the threat of acute serious respiratory covid disease has faded, developing the lingering symptoms of “long covid” remains a concern for people who have had even mild cases. The CDC says vaccination is the “best available tool” to reduce the risk of long covid in children and adults. The exact mechanism is unclear, but experts theorize that vaccines help by reducing the severity of illness, which is a major risk factor for long covid.

When is the best time to get a new coronavirus vaccine?

It depends on your circumstances, including risk factors for severe disease, when you were last infected or vaccinated, and plans for the months ahead. It’s best to talk these issues through with a doctor.

If you are at high risk and have not recently been vaccinated or infected, you may want to get a shot as soon as possible while cases remain high. The summer wave has shown signs of peaking, but cases can still be elevated and take weeks to return to low levels. It’s hard to predict when a winter wave will begin....

Where do I find vaccines?

CVS said its expects to start administering them within days, and Walgreens said that it would start scheduling appointments to receive shots after Sept. 6 and that customers can walk in before then.

Availability at doctor’s offices might take longer. Finding shots for infants and toddlers could be more difficult because many pharmacies do not administer them and not every pediatrician’s office will stock them given low demand and limited storage space.

This year’s updated coronavirus vaccines are supposed to have a longer shelf life, which eases the financial pressures of stocking them.

The CDC plans to relaunch its vaccine locator when the new vaccines are widely available, and similar services are offered by Moderna and Pfizer."

-via The Washington Post, August 22, 2024

[angelx1992]

[alexseanchai]

if someone insists you wear a seat belt, buckling it so the long diagonal strap is behind you is sufficient, like, it's buckled and it's keeping your lap in the seat, what more could they ask?

everyone giving up on masks is so fucking stupid, like it’s like if everyone was like huh, we’ve been wearing seatbelts for a while now and it’s really decreased the amount of injuries people have had in car crashes. let’s all stop wearing them now cause we can’t live in fear forever! no more seatbelts unless you really want one! Oh, you’re still wearing a seatbelt? Didn’t you know you don’t have to use those anymore? why are you being so paranoid?

[crisismonitor]

ΕΟΔΥ: Αποκλιμάκωση στον Covid - Επιμένει η γρίπη

Ενδείξεις ότι η θετικότητα στον Covid 19 υποχωρεί, ενώ για την εποχική γρίπη παραμένει σε υψηλά επίπεδα αναδεικνύει η νέα έκθεση του ΕΟΔΥ. Continue reading ΕΟΔΥ: Αποκλιμάκωση στον Covid – Επιμένει η γρίπη

[truth4ourfreedom]

THE BENEFITS OF IVERMECTIN. IF YOU HAVE CANCER, FREQUENT COLD OR INFECTIONS, MUSCLE SHRINKAGE, CARDIAC ISSUES, CROHNS, HERPES, ETC.

The study was published in the Cureus Journal of Medical Science.  LET'S TALK ABOUT IVERMECTIN 1 – Ivermectin prevents the damage caused to RNA Vaccines.  2 – Ivermectin blocks the entry of Spike Protein into cells.  So, if the person was vaccinated with COVID, they have hope, they have a way to treat themselves through Ivermectin.  3 – Ivermectin is a treatment after Covid and after vaccination, it is an effective medicine in all phases of Covid 19, even before entering the cell, Ivermectin already destroys the virus in the blood.  It only has beneficial effects and no harmful effects in the treatment of the coronavirus.  4 – Ivermectin has a very powerful anti-inflammatory action against Coronavirus.  5 – Ivermectin has a powerful action for traumatic and orthopedic injuries, it strengthens muscles and has no side effects like corticosteroids.  6 – Ivermectin treats autoimmune ailments such as: rheumatoid arthritis, ankylosing spondylitis, fibromyalgia, psoriasis, Crohn's disease, allergic rhinitis.  7 – Ivermectin reduces the frequency of flu and colds.  8 – Ivermectin improves the immunity of cancer patients.  9 – Ivermectin treats Herpes Simplex and Herpes Zoster.  10 – Ivermectin reduces the frequency of sinusitis and diverticulitis.  11 – Ivermectin protects the heart in cardiac overload, in an embolism for example, it prevents cardiac hypoxia because it stimulates the production of basic energy so that the tissue is not destroyed and thus improves cardiac function.  12 – Ivermectin is antiparasitic.  13 – Ivermectin is anti-neoplastic (anti-cancer), it suppresses the proliferation and metastasis of cancer cells, only killing cancer cells and preserving healthy cells, improving the effectiveness of chemotherapy treatment, as it kills cancer cells resistant to chemotherapy, defeating the resistance to multiple chemotherapeutics that tumors develop, and combined with chemotherapy and/or anti-cancer agents, it provides an increase in the effectiveness of these treatments.  14 – Ivermectin is antimicrobial (bacteria and viruses), and increases immunity.  15 – Ivermectin reaches the Central Nervous System and regenerates the nerves.  16 – Ivermectin regulates glucose and insulin metabolism.  17 – Ivermectin regulates cholesterol metabolism.  18 – Ivermectin reduces liver fat in steatose.  19 – Ivermectin protects the liver exposed to insecticides.  20 – Ivermectin attacks the virus wherever it is, regardless of mutations.  21 – Ivermectin serves for the prevention and treatment of coronavirus, surprisingly.  Unproven efficacy is not of Ivermectin, but of vaccines.  22 – Ivermectin, used as a prophylactic agent, was associated with a significant reduction in infection, hospitalization and mortality rates due to COVID-19.  23 - Ivermectin does not attack the liver, since it is not metabolized in it, and if in the intestine, on the contrary, it protects the liver. 

BIG PHARMA DOES NOT WANT YOU TO KNOW THIS.THEY WANT TO SELL YOU THE EXPENSIVE MEDS THEY MAKE BILLIONS ON.

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