#C-peptide
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qualitypeptides · 19 days ago
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Boost Your Health with MOTS-C Peptide
MOTS-C Peptide from Quality Peptides promotes cellular energy, supports metabolism, and enhances overall vitality. Known for its anti-aging benefits, MOTS-C helps combat fatigue and improve physical performance. Experience premium-grade peptides designed for optimal results and unlock the key to a healthier, more energetic you with Quality Peptides.
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drsylvia-blog · 3 months ago
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What is Resilient Skin and How Can You Get It?
The word resilience refers to the ability to adapt well and bounce back from difficult situations. The same also applies to skin resilience or resilient skin, which functions optimally and is able to withstand and recover from everyday stressors. It is also associated with the skin’s ability to defend itself from excessive water loss. Visit us: https://drsylviaskincare.com/blogs/news/what-is-resilient-skin-and-how-can-you-get-it
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lyricsolution-com · 3 months ago
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The Truth About Anti-aging Skincare: 5 Powerful Ingredients That Actually Work | Beauty/Fashion News
In the world of skincare, the quest for youthful, radiant skin is never-ending. With a market flooded by products claiming to erase fine lines, tighten skin, and reverse aging, it can be challenging to distinguish between marketing hype and science-backed solutions. But what truly works when it comes to anti-aging skincare?  Understanding Skin Aging  Aging is a natural process, driven by both…
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purplesnailcosmetics · 4 months ago
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millennialskin · 10 months ago
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Collagen Craze: Exploring the Fountain of Youth for Millennial Skin
Photo by Merve on Pexels.com In the quest for eternal youth, one word consistently emerges as a beacon of hope for millennials seeking to preserve their skin’s vitality: collagen. This crucial protein, abundant in our bodies, is the architect behind firm, supple skin, acting as a crucial building block that keeps our complexions plump, elastic, and radiant. However, as we age, collagen…
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sophie-adam · 11 months ago
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Unlock Radiant Skin with Vitamin C Peptide Serum: A Comprehensive Guide
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Introduction:
Discover the secret to luminous and youthful skin with The Phix's innovative Vitamin C Peptide Serum. In this comprehensive guide, we delve into the powerful combination of vitamin C and peptides, exploring how The Phix's serum revitalizes and transforms your skin for a radiant complexion.
Understanding the Power of Vitamin C and Peptides
The Dynamic Duo for Skin Restoration
Vitamin C and peptides are potent ingredients known for their ability to promote collagen production, fade dark spots, and improve skin texture. When combined, they create a powerhouse serum that targets multiple signs of aging and boosts overall skin health.
Introducing The Phix's Vitamin C Peptide Serum
Elevate Your Skincare Routine
The Phix's Vitamin C Peptide Serum is formulated with a high concentration of vitamin C and peptides to deliver maximum efficacy. This lightweight serum penetrates deep into the skin to brighten, firm, and rejuvenate, leaving you with a smoother, more youthful complexion.
The Benefits of Using The Phix's Serum
Brighten and Even Out Skin Tone
Vitamin C in The Phix's serum helps to brighten and even out skin tone, reducing the appearance of dark spots, sun damage, and hyperpigmentation for a more radiant complexion.
Boost Collagen Production
Peptides stimulate collagen synthesis, improving skin elasticity and firmness. With regular use of The Phix's serum, you'll notice a reduction in fine lines and wrinkles, resulting in smoother, more youthful-looking skin.
Nourish and Hydrate
In addition to its anti-aging benefits, The Phix's serum hydrates and nourishes the skin, replenishing moisture and restoring vitality. Say goodbye to dull, dehydrated skin and hello to a dewy, glowing complexion.
Incorporating The Phix's Serum into Your Skincare Routine
A Step-by-Step Guide to Radiant Skin
Step 1: Cleanse
Start by cleansing your face to remove any dirt, oil, and impurities, allowing The Phix's serum to penetrate more effectively.
Step 2: Apply Serum
Dispense a few drops of The Phix's Vitamin C Peptide Serum onto your fingertips and gently massage it into your skin, focusing on areas of concern such as the face, neck, and décolletage.
Step 3: Follow with Moisturizer
After applying the serum, follow up with your favorite moisturizer to lock in hydration and further nourish the skin. Choose a moisturizer that complements the benefits of The Phix's serum for optimal results.
Step 4: Apply Sunscreen (Daytime Only)
During the daytime, remember to apply sunscreen to protect your skin from harmful UV rays. Opt for a broad-spectrum sunscreen with SPF 30 or higher to shield your skin from premature aging and sun damage.
Conclusion
Elevate your skincare routine and unlock radiant, youthful skin with The Phix's peptide vitamin c serum. Harnessing the power of vitamin C and peptides, this serum delivers targeted solutions for aging skin, leaving you with a smoother, brighter complexion. Trust in The Phix's commitment to skincare innovation and embrace a lifetime of healthy, beautiful skin.
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suroskie · 1 year ago
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Best Anti-Aging Face Serum by Surokie
Unleash the power of our Rounder Glass Skin Serum for the ultimate skincare transformation! Experience exceptional hydration, an all-in-one solution, brightening, and a fortified skin barrier with more than 15 active ingredients. This revolutionary serum fights free radicals, embracing copper peptides, ceramides, and vitamin E. Achieve a flawless, even-toned complexion with Kojic Acid and Polyglutamic Acid. Suitable for all skin types, our anti aging face serum is ideal for those with vitamin C allergies.
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Website:- https://suroskie.com/products/rose-glass-all-rounder-anti-aging-face-serum
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candid-by-teneice · 1 year ago
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One Month Update- Face Routine- The Ultimate Face Routine: How to Achieve Radiant Skin with Our Step-by-Step Guide
One Month Update- Face Routine- The Ultimate Face Routine: How to Achieve Radiant Skin with Our Step-by-Step Guide
Like my new skincare routine is on point 😁💪🏾. No make-up just lip gloss. The Ultimate Face Routine: How to Achieve Radiant Skin with Our Step-by-Step Guide One (1) Month Update!  Okay, take a side-by-side look at my face. This is a 1-month update, and wow, just wow! How I apply my facial products: 1. Cleanse your face thoroughly. Cleanse for 40-60 seconds. 2. Apply the Vitamin C serum. Allow…
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bobbequeen-blog · 2 years ago
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My Favorite Skin Products
Not that I'm the world's beauty expert or anything: Here are my favorite skin products and a couple of my favorite makeup products, too.
These are a few of my favorite, “never go without” skin products. I thought I’d share! Enjoy! My daughter gave me this lotion for Christmas one year. I don’t know what to say other than go buy it. It’s the most luxurious cream I have ever felt in my life and the bonus is that is smells SO GOOD! Yes, it’s expensive, but it’s worth every cent. I swear by it and no, I am not sponsored by them.…
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axonspro · 2 years ago
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The 10 Best Anti-Aging Ingredients for a Youthful Glow 2023
Unlocking the Secrets to Ageless Beauty: Skincare for Every Generation The Top 10 Best Anti-Aging Ingredients for a Youthful Glow 2023 Looking for a youthful glow? These top 10 Best  anti-aging ingredients are the key to fighting signs of aging, including wrinkles, fine lines, and age spots Welcome to the world of ageless beauty, where the secrets to radiant and youthful skin are revealed. In…
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honeytonedhottie · 8 months ago
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lets talk skincare⋆.ೃ࿔*:・🎀
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disclaimer i am NOT a dermatologist so to create this post i did LOTS of research and i'll link all of my sources at the end of the post. i just wanted to kind of put everything that i found in here so i hope its helpful 💕🗒️
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HOW TO DETERMINE UR SKIN TYPE ;
wash ur face with a gentle cleanser, pat dry and wait for about 30 minutes. if ur skin appears shiny throughout then u have oily skin, if ur skin appears tight/flaky then u have dry skin.
if u notice a slight shine on your nose and forehead then you have normal skin. if you have a combination skin type, then the skin will get oily around the t-zone.
INGREDIENTS TO LOOK FOR ;
for skin with acne -> salicylic acid, benzoyl peroxide, sulfur and mandelic acid.
for dry skin -> lactic acid, hyaluronic acid, ceramides and glycerin.
for pigmented skin -> mandelic acid, niacinamide, vitamin C, and arbutin.
INGREDIENTS THAT U SHOULD NOT MIX ;
mixing retinol and vitamin C causes irritation, mixing vitamin C and glycolic acid results in over-exfoliation, mixing AHA and retinol causes extreme dryness.
INGREDIENTS THAT U SHOULD MIX ;
hyaluronic acid + ceramides = repairing skin barrier. niacinimide + salicylic acid = healing acne. retinol + niacinimide = collagen production.
GLOWY SKIN TIPS ;
use a cleansing balm to cleanse ur face to remove all the impurities from ur skin
use serums to hydrate ur skin
lather on moisturizer, dont put too much to the point where ur skin cannot produce its own oils, but you MUST moisturize
apply sunscreen everyday, not only on ur face but also on ur neck and hands
face masks 1-2x a week
get enough sleep, drink enough water, and steer clear of overly processed foods
SKINCARE DOESNT STOP AT UR CHIN ;
its important to take care of the skin on ur neck for SO many reasons because skincare doesnt stop at ur chin. ur neck reflects the first signs of aging, and its most susceptible to sun damage so show it some love!
use the same products that u use on ur face on ur neck also, moisturize ur neck and always apply sunscreen, lastly, use some retinol to build collagen.
HOW TO APPLY RETINOL ;
when applying retinol, use a pea sized amount. avoid application around ur eyes and the openings in ur nose, and use retinol in ur night skincare routine only.
HOW OFTEN TO USE SKINCARE ;
retinol should be used nightly (1-2x a week for beginners). hyaluronic acid should be used (2x a day). salicylic acid should be used (1-2x a week). sunscreen should be applied daily, no need to apply it at night and if u can, you should reapply it every 2-3 hours. vitamin C (1x a day in the morning).
SERUMS FOR UR SKIN-TYPE ;
for oily skin use -> salicylic acid, niacinimide and mandelic acid.
for dry skin use -> hyaluronic acid, ceramides and lactic acid.
for normal skin use -> vitamin C, glycolic acid, and retinol.
for aging skin use -> peptides, retinol and vitamin C.
for acne prone skin use -> salicylic acid, retinol, and niacinimde.
for combination skin use -> mandelic acid, niacinimide, and glycolic acid.
WHAT TYPE OF FACEMASK IS BEST FOR YOU ;
cream masks are good for all skin-types and it soothes and moisturizes. clay masks are good for oily or acne prone skin and it absorbs oil and controls shine. charcoal masks are good for oily or acne prone skin, and it deep cleanses and unclogs.
sheet masks are good for all skin-types, it nourishes and hydrates. enzyme masks are good for all skin-types and it gently exfoliates and brightens the skin. bubble masks are good for all skin-types and it hydrates and soothes.
gel masks are good for all skin-types and it provides a cooling effect. exfoliating masks are good for all skin-types BUT if u have sensitive skin then exfoliating masks are not for you. exfoliating masks remove dead skin cells and debris.
HOW TO LAYER UR SKINCARE ;
in the morning (cleanser + toner + hydrating serum + vitamin c + moisturizer + sunscreen) in the evening (double cleanse + toner + hydrating serum + retinol + moisturizer)
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covid-safer-hotties · 4 months ago
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Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategy - Published Sept 21, 2003
Yes, you are reading that date right
Never let them tell you "we didn't know the risk." They knew. They just ignored all epidemiological best practices. For corporate profit.
Abstract Background Severe acute respiratory syndrome (SARS) is a febrile respiratory illness. The disease has been etiologically linked to a novel coronavirus that has been named the SARS-associated coronavirus (SARS-CoV), whose genome was recently sequenced. Since it is a member of the Coronaviridae, its spike protein (S2) is believed to play a central role in viral entry by facilitating fusion between the viral and host cell membranes. The protein responsible for viral-induced membrane fusion of HIV-1 (gp41) differs in length, and has no sequence homology with S2. Results Sequence analysis reveals that the two viral proteins share the sequence motifs that construct their active conformation. These include (1) an N-terminal leucine/isoleucine zipper-like sequence, and (2) a C-terminal heptad repeat located upstream of (3) an aromatic residue-rich region juxtaposed to the (4) transmembrane segment. Conclusions This study points to a similar mode of action for the two viral proteins, suggesting that anti-viral strategy that targets the viral-induced membrane fusion step can be adopted from HIV-1 to SARS-CoV. Recently the FDA approved Enfuvirtide, a synthetic peptide corresponding to the C-terminal heptad repeat of HIV-1 gp41, as an anti-AIDS agent. Enfuvirtide and C34, another anti HIV-1 peptide, exert their inhibitory activity by binding to a leucine/isoleucine zipper-like sequence in gp41, thus inhibiting a conformational change of gp41 required for its activation. We suggest that peptides corresponding to the C-terminal heptad repeat of the S2 protein may serve as inhibitors for SARS-CoV entry.
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theambitiouswoman · 9 days ago
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Bath Routine 🫧🛁✨
1. I dim the lights, light candles & play classical music. If candles aren’t available, I use an oil diffuser with lavender or eucalyptus scents.
2. I add Epsom salts, milk powder, a few drops of nourishing oils like rosehip, argan, or jojoba. I also like to add dried rose petals for a soothing touch. If I want to detox, I add charcoal and bentonite clay.
3. I shower before my bath to cleanse my body of dirt, oils, sweat. I will use a shower oil during this step to hydrate, cleanse and exfoliate (will do separate post for everything shower).
Pre bath routine:
4. I dry brush to stimulate circulation.
5. I wash my face and remove makeup if applicable. I then use a face steamer for about 5 minutes to open my pores.
6. I apply my favorite face mask (either DIY or store bought) before stepping into the bath (will do a separate post on this).
In the bath:
7. While in the bath, I lightly use exfoliating gloves or a scrub to exfoliate my body.
8. I massage my face with ice globes to reduce puffiness and stimulate circulation.
9. I sip on tea, a magnesium cocktail, or infused water.
Post bath routine:
10. After my bath, I wash off my face mask and apply toner to close my pores.
11. I apply my favorite serums to hydrate and nourish my skin. After applying serums, I use a jade or rose quartz facial roller to help the products absorb better and promote lymphatic drainage.
12. I apply body oil or lotion all over my body to lock in moisture & keep my skin soft.
13. I apply a nourishing hand and nail treatment to hydrate my hands, cuticles and nails.
14. I brush my hair if I didn’t wash it (separate post on this coming soon).
15. I apply my favorite perfume to feel extra luxurious.
16. I put on a silk robe to complete my relaxing routine.
17. After my skincare routine, I use my LED mask. Your skin is more receptive to hydration after cleansing & applying serums & the mask enhances absorption of active ingredients like hyaluronic acid, peptides, or Vitamin C. It also stimulates collagen production & skin repair.
18. After using the LED mask, I apply a moisturizer to lock in hydration.
Then continue on with my night time routine.
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pleaseeeimjustagirl · 7 months ago
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🌷Summer Skincare Recommendations🌷
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Hey babesss the summer is officially hereeeeee and I am so excited and I need to keep my girliesss skincare in check okay! So I will be listing my skincare favorites below that you can purchase on Amazon. Always consult your dermatologist and do your thorough research on these products to see if they will benefit your skin type. I will be rating everything out of 5 stars⭐️ <3333
Cleansers 
♡ ANUA Heartleaf Quercetinol Pore Deep Cleansing Foam
⭐️ ⭐️ ⭐️ ⭐️ ⭐️
♡ ANUA Heartleaf Pore Control Cleansing Oil ⭐️ ⭐️ ⭐️ ⭐️ ⭐️
♡ Beauty of Joseon Green Plum Refreshing Cleanser Gel
⭐️ ⭐️ ⭐️ ⭐️
♡ ROUND LAB 1025 Dokdo Cleanser ⭐️ ⭐️ ⭐️ ⭐️
♡ COSRX Low pH Good Morning Gel Cleanser ⭐️ ⭐️ ⭐️
Toners 
♡ I'm from Rice Toner Milky Toner for Glowing Skin ⭐️ ⭐️ ⭐️ ⭐️
♡ ANUA Heartleaf 77 Soothing Toner ⭐️ ⭐️ ⭐️ ⭐️ ⭐️
♡ Beauty of Joseon Ginseng Essence Water Hydrating Face Toner ⭐️ ⭐️ ⭐️ ⭐️
♡ ANUA Heartleaf 77 Toner Pad ⭐️ ⭐️ ⭐️ ⭐️ ⭐️
♡ Beauty of Joseon Glow Replenishing Rice Facial Sebum Toner for Oily Combination Acne Skin ⭐️ ⭐️ ⭐️ ⭐️ ⭐️
♡ COSRX AHA/BHA Clarifying Treatment Toner ⭐️ ⭐️ ⭐️ ⭐️ ⭐️
Serums 
♡ Topicals Faded Brightening and Clearing Serum ⭐️ ⭐️ ⭐️ ⭐️ ⭐️
♡ Beauty of Joseon Glow Serum Propolis and Niacinamide Hydrating Facial ⭐️ ⭐️ ⭐️ ⭐️
♡ SKIN1004 Madagascar Centella Asiatica Ampoule Facial Serum ⭐️ ⭐️ ⭐️ ⭐️
♡ Youth To The People 15% Vitamin C Face Serum ⭐️ ⭐️ ⭐️
♡ Anua Peach 70 Niacinamide Serum ⭐️ ⭐️ ⭐️ ⭐️ ⭐️
Moisturizers 
♡ Bio-Oil Skincare Body Oil, Serum for Scars and Stretchmarks, Face Moisturizer ⭐️ ⭐️ ⭐️ ⭐️ ⭐️
♡ Beauty of Joseon Dynasty Cream Hydrating Face Moisturizer
⭐️ ⭐️ ⭐️ ⭐️
♡ Illiyoon Ceramide Ato Concentrate Cream Korean Moisturizer
⭐️ ⭐️ ⭐️ ⭐️
Eyecreams 
♡ Medicube Deep Reviving Peptide Eye Cream ⭐️ ⭐️ ⭐️ ⭐️ ⭐️
♡ COSRX Retinol Cream, 0.67 Oz, Anti-aging Eye & Neck Cream with Retinoid ⭐️ ⭐️ ⭐️
♡ Beauty of Joseon Revive Eye Serum with Retinal Niacinamide Correction ⭐️ ⭐️ ⭐️ ⭐️
Sunscreen 
♡ ROUND LAB Birch Juice Moisturizing Sunscreen ⭐️ ⭐️ ⭐️ ⭐️
♡ Neutrogena Clear Face Liquid Lotion Sunscreen ⭐️ ⭐️ ⭐️ ⭐️ ⭐️
♡ La Roche-Posay Anthelios Light Fluid Facial Sunscreen ⭐️ ⭐️ ⭐️
Face Masks 
♡ COSRX Snail Mucin Sheet Mask ⭐️ ⭐️ ⭐️ ⭐️
♡ Collagen Lifting Mask ⭐️ ⭐️ ⭐️ ⭐️ ⭐️
♡ Aztec Secret Indian Healing Clay Deep Pore Cleansing Facial & Body Mask ⭐️ ⭐️ ⭐️ ⭐️
Skincare Tools
♡ BAIMEI Jade Roller & Gua Sha Set Face Roller and Gua Sha Facial Tools
♡ Colorfarm Facial Steamer Nano Ionic: Face Steamer Deep Cleaning Unclogs Pores - Humidifier
♡ Ice Roller for Face, Ice Face Roller & Eye Puffiness Relief
♡ 7 Colors Led Light Therapy Facial Mask, Face Light Therapy Mask for Face
♡ NuFACE MINI+ Microcurrent Facial Device Kit - FDA Cleared Face Sculpting & Skin Tightening Device
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sophie-adam · 1 year ago
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Revitalize Your Skin with Collagen Peptide Serums
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Introduction:
Embark on a journey to radiant and revitalized skin with The Phix. This article explore into the transformative power of Collagen Peptide Serum and peptide facial serum, a dynamic duo crafted for ultimate skin renewal. Discover the science behind peptides, collagen, and Vitamin C, and how this combination becomes the cornerstone of your skincare routine.
Elevating Your Skincare with The Phix:
The Power of Collagen Peptide Serum
Uncover the magic of The Phix Collagen Peptide Serum. Delve into how peptides stimulate collagen production, promoting skin elasticity and reducing the appearance of fine lines and wrinkles. Learn why this serum is a vital component in achieving a firm, youthful complexion.
Vitamin C Peptide Serum: The Radiance Solution
Explore the benefits of The Phix peptide vitamin c serum. From brightening your complexion to acting as a powerful antioxidant, understand how Vitamin C contributes to a radiant and healthy skin tone. Discover the dual action of collagen and Vitamin C working harmoniously for skin perfection.
The Perfect Harmony: Collagen and Vitamin C Peptide Serum
Why The Phix Peptide Serums:
Unmatched Quality and Efficacy
Explore The Phix commitment to quality and efficacy in skincare. From sourcing premium ingredients to the meticulous crafting of each serum, understand why The Phix Peptide Serums are unparalleled in delivering transformative results.
Daily Rituals with Collagen Peptide Serum
Incorporate The Phix Collagen Peptide Serum into your daily ritual and witness the transformative effects. This section provides insights into the ideal application, emphasizing its lightweight texture that absorbs effortlessly into your skin. Learn how to make this serum a staple, creating a foundation for a radiant and resilient complexion.
Vitamin C Peptide Serum: A Burst of Freshness Every Day
Explore the refreshing burst of The Phix peptide vitamin c serum. Understand the optimal usage, whether as a revitalizing morning boost or a rejuvenating nighttime treat. This section highlights the versatility of the serum, ensuring that you can infuse your skin with Vitamin C goodness at any time for a continuous, radiant glow.
The Phix Promise: Radiant Skin, Every Serum Drop
Dive into The Phix commitment to radiant skin. From the careful selection of ingredients to the advanced formulations, grasp the essence of The Phix Promise. Every drop of Collagen Peptide and Vitamin C Peptide Serum is designed to contribute to your journey of achieving radiant, youthful, and revitalized skin.
Elevate Your Beauty Ritual with The Phix:
Collagen and Vitamin C Peptide Serum Experience
Immerse yourself in the experience of using The Phix Collagen Peptide and peptide vitamin c serum together. This section explores how this dynamic duo enhances each other's benefits, providing a comprehensive solution for a radiant and healthy complexion. Discover the joy of a skincare routine that truly elevates your beauty ritual.
Conclusion:
In conclusion, The Phix Collagen Peptide and peptide facial serum redefines your skincare journey. Elevate your routine with the power of peptides, collagen, and Vitamin C, unlocking the secret to radiant, youthful, and revitalized skin. Embrace The Phix promise of quality, efficacy, and the beauty that radiates from within.
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hellsite-proteins · 6 months ago
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I have a bio exam in about six hours (in the afternoon, this is an appropriate hour for me to be awake) and I don't wanna study so I'm gonna recite everything I know about proteins to you.
Proteins can have CHONS, Carbon Hydrogen Oxygen Nitrogen Sulfur. Made up of amino acids. Amino acids have NH2-R-C-H-COOH. NH2 is the amino group and COOH is the uhh carboxyl group? Amino acids exist as zwitterions, with the NH2 becoming NH3- and COOH becoming COO-. Because electronegativity and stuff. There are 20 amino acids (in my syllabus).
Proteins have primary structure (polypeptide chain, the specific sequence of amino acids) listed from N terminus to C terminus. Maintained by peptide bonds. Which is a condensation reaction. The COOH and the NH2 form a bond that looks like CONH. Then secondary structure, which is alpha helixes and beta sheets. Both are maintained by hydrogen bonds. Beta sheets can be parallel or antiparallel, though most of the ones in your blog or antiparallel (but also very short). Alpha helixes are more common and recognisable.
Next is tertiary structure. Four types of bonds in this one: Hydrogen bonds, ionic bonds, disulfide bonds, and hydrophobic interactions. In increasing order of strength, hydrophobic<hydrogen<ionic<disulfide. Disulfide bonds are covalent bonds and very heat stable. Formed by disulfide bridges. Very strong. Sulfur is found on Cysteine so the more cysteine is in a molecule the more heat stable it is likely to be. The single letter code for Cysteine is C. If I say CCCCCCCCCCCC, will disulfide bridges form in my protein? Hm. Ionic bonds is when uhh. Charged particles. Shit I forgot I need to revise this part. Hydrogen bonds are easier, I can identify them by identifying differences in electronegativity- in chem I remember these as FON and H, but in amino acids there's only O and N, no Fluorine. Very common, in most secondary structures. In polar particles or R groups. Ionic bonds are for charged particles, hydrogen bonds are for polar particles. Lastly in hydrophobic interactions, not to be confused with homophobic interactions. Which is when hydrophobic side chains- most commonly stuff with lots of carbon, or sometimes sulfur- gather in the middle of the protein, away from the aqueous exterior.
Next is Quaternary structure, which is when there are MULTIPLE polypeptide chains. Only when multiple polypeptide chains, if not it's tertiary. Not all proteins have these. Bonds are mostly the same as tertiary, I think?
CCCCCCCCCCCCCCCC.
There are globular, fibrous, and membrane proteins. But mostly I have to focus on the globular and fibrous part. My case study for globular proteins is haemoglobin. Haemoglobin has four polypeptide chains in it's quaternary structure, two alpha two beta. It is unclear if the names of the chains have anything to do with whether there are alpha helixes or beta sheets in them. It also has a prosthetic group, a haem group in this case, of iron- I think an Fe2+ molecule? Yeah. Which oxygen binds to. And once oxygen is bound to it it causes a change in confirmation in all four parts allowing it to bind to oxygen more easily. I need to know about sickle cell disease, which is when one of the amino acids- glutamic acid I think- is replaced with a hydrophobic one. Serine? Either way when oxygen is bound to it it's fine but when there's no oxygen there's a hydrophobic patch sticking out, which it doesn't like so the haemoglobin will change confirmation to hide, causing the haemoglobin to clump together in a way that causes the red blood cell to appear "sickle shaped". Also I was wrong it's not serine it's valine.
For fibrous, I have collagen. Which is mostly a repeating sequence of three amino acids- shit I forgot which ones I need to get my notes- glycine-X-Y. Glycine has a very small R group which allows it to fit in the small tight part in the alpha helix. X-Y is usually proline and hydroxyproline. Alpha helix, hydrogen bonds formed. Proline and hydroxyproline have relatively inflexible and bulky R groups which gives the structure rigidity. That's the secondary structure. But collagen is unique in that it has a secondary and quaternary structure, because in tropocollagen it's like three of these alpha helixes wound together. Then each tropocollagen cross links to neighbouring tropocollagen molecules. This is covalent bonds involving lysine residues. Lysine??? Where tf did Lysine come from??? I don't see it anywhere else on the page. This is worrying. Uhh this increases tensile strength and the staggered or overlapping arrangement of tropocollagen minimises points of weakness along the length of the fibrils. It's like, collagenchain-tropocollagen-fibrils-fibres. The staggering gives the bundle of fibrils a banded appearance. There was... A part where they talk about how the cell produces it on the outside... No, wait, that's cellulose. Carbohydrate. Completely different.
Then we move on to enzymes which is a whole different chapter and this is already a very long ask which I imagine will take very long to load. Thank you for letting me ramble in your inbox. CCCCCCCCC. I'm going to ramble about DNA&genomics to hellsitegenetics in a bit but first I need to finish looking through mitosis and meiosis. Ugh. I hope this protein has a high success rate and that my exam has an even higher success rate. Thank you for your time.
this sounds great and i bet you did awesome on your exam! i find explaining things to someone else helpful when studying, so i hope that doing this helped you as well. without even looking at it i can guarantee that your exam was much more successful than whatever proteins i'll get out of this.
i actually had to split this into two proteins and run them completely separately because it was simply too long. i am both excited and absolutely terrified to see what we get from all those cysteines
letter sequence in this ask matching protein-coding amino acids:
protein 1:
IhaveaieaminatsihrsintheafternnthisisanapprpriatehrfrmeteawakeandIdntwannastdysImgnnareciteeverythingIknwatprteinstyPrteinscanhaveCHNSCarnHydrgenygenNitrgenSlfrMadepfaminacidsAminacidshaveNHRCHCHNHistheamingrpandCHisthehhcarylgrpAminacidseistaswitterinswiththeNHecmingNHandCHecmingCecaseelectrnegativityandstffThereareaminacidsinmysyllasPrteinshaveprimarystrctreplypeptidechainthespecificseqencefaminacidslistedfrmNterminstCterminsMaintainedypeptidendsWhichisacndensatinreactinTheCHandtheNHfrmandthatlkslikeCNHThensecndarystrctrewhichisalphaheliesandetasheetstharemaintainedyhydrgenndsetasheetscaneparallelrantiparallelthghmstfthenesinyrlgrantiparalleltalsveryshrtAlphaheliesaremrecmmnandrecgnisaleNetistertiarystrctreFrtypesfndsinthisneHydrgenndsinicndsdislfidendsandhydrphicinteractinsInincreasingrderfstrengthhydrphichydrgeninicdislfideDislfidendsarecvalentndsandveryheatstaleFrmedydislfideridgesVerystrngSlfrisfndnCysteinesthemrecysteineisinamleclethemreheatstaleitislikelyteThesinglelettercdefrCysteineisCIfIsayCCCCCCCCCCCCwilldislfideridgesfrminmyprteinHmInicndsiswhenhhChargedparticlesShitIfrgtIneedtrevisethispartHydrgenndsareeasierIcanidentifythemyidentifyingdifferencesinelectrnegativityinchemIrememertheseasFNandHtinaminacidstheresnlyandNnFlrineVerycmmninmstsecndarystrctresInplarparticlesrRgrpsInicndsarefrchargedparticleshydrgenndsarefrplarparticlesLastlyinhydrphicinteractinsnttecnfsedwithhmphicinteractinsWhichiswhenhydrphicsidechainsmstcmmnlystffwithltsfcarnrsmetimesslfrgatherinthemiddleftheprteinawayfrmtheaqeseterirNetisQaternarystrctrewhichiswhenthereareMLTIPLEplypeptidechainsnlywhenmltipleplypeptidechainsifntitstertiaryNtallprteinshavethesendsaremstlythesameastertiaryIthink
protein 2:
CCCCCCCCCCCCCCCCTherearegllarfirsandmemraneprteinstmstlyIhavetfcsnthegllarandfirspartMycasestdyfrgllarprteinsishaemglinHaemglinhasfrplypeptidechainsinitsqaternarystrctretwalphatwetaItisnclearifthenamesfthechainshaveanythingtdwithwhethertherearealphaheliesretasheetsinthemItalshasaprstheticgrpahaemgrpinthiscasefirnIthinkanFemlecleYeahWhichygenindstAndnceygenisndtititcasesachangeincnfirmatininallfrpartsallwingittindtygenmreeasilyIneedtknwatsicklecelldiseasewhichiswhenneftheaminacidsgltamicacidIthinkisreplacedwithahydrphicneSerineEitherwaywhenygenisndtititsfinetwhentheresnygentheresahydrphicpatchstickingtwhichitdesntlikesthehaemglinwillchangecnfirmatinthidecasingthehaemglintclmptgetherinawaythatcasestheredldcelltappearsickleshapedAlsIwaswrngitsntserineitsvalineFrfirsIhavecllagenWhichismstlyarepeatingseqencefthreeaminacidsshitIfrgtwhichnesIneedtgetmyntesglycineYGlycinehasaverysmallRgrpwhichallwsittfitinthesmalltightpartinthealphaheliYissallyprlineandhydryprlineAlphahelihydrgenndsfrmePrlineandhydryprlinehaverelativelyinfleileandlkyRgrpswhichgivesthestrctrerigidityThatsthesecndarystrctretcllagenisniqeinthatithasasecndaryandqaternarystrctreecaseintrpcllagenitslikethreefthesealphahelieswndtgetherTheneachtrpcllagencrsslinkstneighringtrpcllagenmleclesThisiscvalentndsinvlvinglysineresidesLysineWheretfdidLysinecmefrmIdntseeitanywhereelsenthepageThisiswrryinghhthisincreasestensilestrengthandthestaggeredrverlappingarrangementftrpcllagenminimisespintsfweaknessalngthelengthfthefirilsItslikecllagenchaintrpcllagenfirilsfiresThestaggeringgivesthendleffirilsaandedappearanceTherewasApartwheretheytalkathwthecellprdcesitnthetsideNwaitthatscelllseCarhydrateCmpletelydifferentThenwemventenymeswhichisawhledifferentchapterandthisisalreadyaverylngaskwhichIimaginewilltakeverylngtladThankyfrlettingmeramleinyrinCCCCCCCCCImgingtramleatDNAgenmicsthellsitegeneticsinaittfirstIneedtfinishlkingthrghmitsisandmeisisghIhpethisprteinhasahighsccessrateandthatmyeamhasanevenhighersccessrateThankyfryrtime
protein guy analysis:
protein 1 looks absolutely awful. it barely has any secondary structure, and absolutely no tertiary structure to speak of. the horrifying loops have some strings of cis bonds, and there is not a single disulfide bond. i hate this so much. the long string of C's just looks off putting. protein 2 is the same but worse. there is one disulfude, but otherwise barely any structure exists. the single alpha helix feels almost mocking. overall, this is miserable and disgusting.
predicted protein structure:
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protein 1 cartoon
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protein 1 surface
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close up of cysteines on protein 1
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protein 2 cartoon with disulfide bond in orange
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protein 2 surface
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