#C-peptide
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Boost Your Health with MOTS-C Peptide
MOTS-C Peptide from Quality Peptides promotes cellular energy, supports metabolism, and enhances overall vitality. Known for its anti-aging benefits, MOTS-C helps combat fatigue and improve physical performance. Experience premium-grade peptides designed for optimal results and unlock the key to a healthier, more energetic you with Quality Peptides.
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What is Resilient Skin and How Can You Get It?
The word resilience refers to the ability to adapt well and bounce back from difficult situations. The same also applies to skin resilience or resilient skin, which functions optimally and is able to withstand and recover from everyday stressors. It is also associated with the skin’s ability to defend itself from excessive water loss. Visit us: https://drsylviaskincare.com/blogs/news/what-is-resilient-skin-and-how-can-you-get-it

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The Truth About Anti-aging Skincare: 5 Powerful Ingredients That Actually Work | Beauty/Fashion News
In the world of skincare, the quest for youthful, radiant skin is never-ending. With a market flooded by products claiming to erase fine lines, tighten skin, and reverse aging, it can be challenging to distinguish between marketing hype and science-backed solutions. But what truly works when it comes to anti-aging skincare? Understanding Skin Aging Aging is a natural process, driven by both…
#anti-aging skincare#best anti-aging ingredients#how to slow aging#Hyaluronic acid benefits#niacinamide anti-aging#peptides for skin#retinoids for aging skin#SKINCARE ROUTINE#vitamin C for wrinkles
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#beauty#face serum#vitamin c serum#collagen peptides#retinol#sunscreen#oily skin#skincare routine#acne treatment#Glass glow#korean
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Unlock Radiant Skin with Vitamin C Peptide Serum: A Comprehensive Guide
Introduction:
Discover the secret to luminous and youthful skin with The Phix's innovative Vitamin C Peptide Serum. In this comprehensive guide, we delve into the powerful combination of vitamin C and peptides, exploring how The Phix's serum revitalizes and transforms your skin for a radiant complexion.
Understanding the Power of Vitamin C and Peptides
The Dynamic Duo for Skin Restoration
Vitamin C and peptides are potent ingredients known for their ability to promote collagen production, fade dark spots, and improve skin texture. When combined, they create a powerhouse serum that targets multiple signs of aging and boosts overall skin health.
Introducing The Phix's Vitamin C Peptide Serum
Elevate Your Skincare Routine
The Phix's Vitamin C Peptide Serum is formulated with a high concentration of vitamin C and peptides to deliver maximum efficacy. This lightweight serum penetrates deep into the skin to brighten, firm, and rejuvenate, leaving you with a smoother, more youthful complexion.
The Benefits of Using The Phix's Serum
Brighten and Even Out Skin Tone
Vitamin C in The Phix's serum helps to brighten and even out skin tone, reducing the appearance of dark spots, sun damage, and hyperpigmentation for a more radiant complexion.
Boost Collagen Production
Peptides stimulate collagen synthesis, improving skin elasticity and firmness. With regular use of The Phix's serum, you'll notice a reduction in fine lines and wrinkles, resulting in smoother, more youthful-looking skin.
Nourish and Hydrate
In addition to its anti-aging benefits, The Phix's serum hydrates and nourishes the skin, replenishing moisture and restoring vitality. Say goodbye to dull, dehydrated skin and hello to a dewy, glowing complexion.
Incorporating The Phix's Serum into Your Skincare Routine
A Step-by-Step Guide to Radiant Skin
Step 1: Cleanse
Start by cleansing your face to remove any dirt, oil, and impurities, allowing The Phix's serum to penetrate more effectively.
Step 2: Apply Serum
Dispense a few drops of The Phix's Vitamin C Peptide Serum onto your fingertips and gently massage it into your skin, focusing on areas of concern such as the face, neck, and décolletage.
Step 3: Follow with Moisturizer
After applying the serum, follow up with your favorite moisturizer to lock in hydration and further nourish the skin. Choose a moisturizer that complements the benefits of The Phix's serum for optimal results.
Step 4: Apply Sunscreen (Daytime Only)
During the daytime, remember to apply sunscreen to protect your skin from harmful UV rays. Opt for a broad-spectrum sunscreen with SPF 30 or higher to shield your skin from premature aging and sun damage.
Conclusion
Elevate your skincare routine and unlock radiant, youthful skin with The Phix's peptide vitamin c serum. Harnessing the power of vitamin C and peptides, this serum delivers targeted solutions for aging skin, leaving you with a smoother, brighter complexion. Trust in The Phix's commitment to skincare innovation and embrace a lifetime of healthy, beautiful skin.
#vitamin c peptide serum#peptide vitamin c serum#peptide facial serum#super peptide serum#peptide serums#phix philler#the phix#the phix philler#rebuild phix philler
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Best Anti-Aging Face Serum by Surokie
Unleash the power of our Rounder Glass Skin Serum for the ultimate skincare transformation! Experience exceptional hydration, an all-in-one solution, brightening, and a fortified skin barrier with more than 15 active ingredients. This revolutionary serum fights free radicals, embracing copper peptides, ceramides, and vitamin E. Achieve a flawless, even-toned complexion with Kojic Acid and Polyglutamic Acid. Suitable for all skin types, our anti aging face serum is ideal for those with vitamin C allergies.

Website:- https://suroskie.com/products/rose-glass-all-rounder-anti-aging-face-serum
#rose face serum#anti aging face serum#copper peptide serum#ceramide face serum#kojic acid face serum#vitamin c face serum
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One Month Update- Face Routine- The Ultimate Face Routine: How to Achieve Radiant Skin with Our Step-by-Step Guide
One Month Update- Face Routine- The Ultimate Face Routine: How to Achieve Radiant Skin with Our Step-by-Step Guide
Like my new skincare routine is on point 😁💪🏾. No make-up just lip gloss. The Ultimate Face Routine: How to Achieve Radiant Skin with Our Step-by-Step Guide One (1) Month Update! Okay, take a side-by-side look at my face. This is a 1-month update, and wow, just wow! How I apply my facial products: 1. Cleanse your face thoroughly. Cleanse for 40-60 seconds. 2. Apply the Vitamin C serum. Allow…
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#Amazon#before and after#before and after face#Collagen cream#face routine#Hyaluronic Acid#Peptide#Retino#Retinol#Vitamin C serum
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My Favorite Skin Products
Not that I'm the world's beauty expert or anything: Here are my favorite skin products and a couple of my favorite makeup products, too.
These are a few of my favorite, “never go without” skin products. I thought I’d share! Enjoy! My daughter gave me this lotion for Christmas one year. I don’t know what to say other than go buy it. It’s the most luxurious cream I have ever felt in my life and the bonus is that is smells SO GOOD! Yes, it’s expensive, but it’s worth every cent. I swear by it and no, I am not sponsored by them.…

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#Brazilian Bum Bum Cream#coconuts#lotions#Makeup#Milani#moisturizer#Peptides#skincare#stick blush#TruSkin Products#Vitamin C lotion#Vitamin C Serum
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The 10 Best Anti-Aging Ingredients for a Youthful Glow 2023
Unlocking the Secrets to Ageless Beauty: Skincare for Every Generation The Top 10 Best Anti-Aging Ingredients for a Youthful Glow 2023 Looking for a youthful glow? These top 10 Best anti-aging ingredients are the key to fighting signs of aging, including wrinkles, fine lines, and age spots Welcome to the world of ageless beauty, where the secrets to radiant and youthful skin are revealed. In…

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#Additional Tips for Ageless Beauty#and age spots#anti-aging products#Ceramides: The Moisture Protectors#CoQ10: The Cellular Protector#fine lines#Green Tea Extract: The Rejuvenating Antioxidant#Hyaluronic Acid: The Hydration Hero#including wrinkles#ingredients are the key to fighting signs of aging#Peptides: The Collagen Boosters#Resveratrol: The Fountain of Youth#The 10 Best Anti-Aging Ingredients for a Youthful Glow 2023#The Powerhouse Ingredient#Vitamin C: The Radiance Booster#Vitamin E: The Nourishing Defender
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beauty tips to look less like you're actively dying
now of course, if you're following my nutrition tips, you should mitigate the living corpse appearance anyways, but here's makeup, skin, hair, and nail options to keep up the appearance of a normal person
Skin: Using a silicone scrubbie, take off makeup and wash face with an oil cleanser, then wash again with a regular gel cleanser. In the morning, vitamin C serum and then a day cream containing retinol and spf. At night, just petroleum jelly. Cerave sells all of these for cheap and they're recommended by my dermatologist. Use the petroleum jelly on your lips, too. During the day, use carmex chapstick religiously. For your body, use exfoliating body wash and exfoliating gloves. Naturium glycolic acid body wash and bio-lipid lotion are my holy grails. Makeup: You want to look dewy and rested. No matte makeup, it'll settle into your dry skin and you'll look worse. Start with Covergirl trublend in plush plump (or the greenish one if you have redness) to give off the appearance of plumper skin and prime your face. Assuming you have dark circles, you want an undereye brightener. I like Catrice's, you could also layer this over l'oreal's anti-fatigue magic skin beautifier if your dark circles are really bad. No heavy foundation - go for a bb cream. L'oreal magic skin or, my personal fave, wet n wild bare focus skin tint. For blush, avoid pink or peach - you want a shade that'll look natural. Most makeup artists use a red or a berry. If you wear red or berry lipsticks, just use lipstick as your blush, that's what I do with my clinique black honey (which is a great shade for this if you have olive skin). If you're going for red, a great, cheaper option for this would be sheglam colorbloom liquid blush or simply your lipstick like I said. Another berry option that's cheaper than my clinique would be something like wet n wild in my blackberry broke. You'll want a glassy, not powdery highlighter. This can be l'oreal lumiglotion, wet n wild radiance liquid, or an actual highlighter like l'oreal lumi le glass. For powder, just powder your t zone very gently with something like elf halo glow or the catrice blurring loose powder. Do your eye makeup and eyebrows however you want, though I personally recommend learning how to do them properly for your face shape and "animal face type" and learn your color season so everything harmonizes. Set everything down with Milani make it last dewy setting spray. Hair: It needs moisture and volume. A good cheap option is Pacifica salty waves if you don't color your hair and coco peptides if you do. Do a big deep conditioning treatment once a week. marc anthony grow long, l'oreal elvive, or pantene miracle rescue are all good options. Consider oiling your hair, too. research how to do it and what oil to use for your specific hair type. Use a mousse for volume - pacifica makes one that smells like vanilla. You'll scrunch this into your hair when it's soaking wet after your shower. Spritz with a sea salt spray after - ouai is the best, but it's pricy, so feel free to use pacifica's for this as well. Make sure also to trim your dead ends and get a flattering haircut that isn't flat - it'll be easier to hide any thinning with layers, and you won't get the stringy anorexia look. Nails: Get a nail oil, a cuticle remover, and keep your nails trimmed and cleaned, then start wearing press ons (or get gel tips if you can afford it). Bliss kiss nail oil pens are a great option, blue cross cuticle remover, and kiss are cheap, solid press ons. I like the medium length square french, but I was also born in the 90s.
#34t1ng d1s0rd3r#@na motivation#m34nspo#th!nsp0#tw 3d vent#4n@diary#light as a feather#4nor3xia#3d not sheeran#tw ed ana#3ating d1sorder#tw ana bløg#thinspø
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gelatin gummies for glowy skin


not only fun to make but also incredibly efficient, packed with collagen, antioxidants, and skin-nourishing ingredients:
Ingredients:
• 2 cups liquid: you can use fresh orange juice, pomegranate juice, or green tea (rich in antioxidants and vitamin C).
• 3 tbsp unflavored gelatin: this provides the collagen for skin elasticity and hydration.
• 1 tbsp honey or maple syrup: a natural sweetener for taste (optional).
• 1 tsp lemon juice: adds extra vitamin C for skin brightness.
Instructions:
prepare the liquid. heat your juice or tea in a small saucepan over medium heat. don’t let it boil; you just want it warm (around 120°F/50°C) to preserve nutrients.
Dissolve the gelatin. slowly sprinkle the gelatin over the warm liquid while whisking continuously. this ensures it dissolves completely without clumping.
sweeten and enhance. stir in honey, lemon juice, and any optional add-ins (like collagen peptides) until fully dissolved.
pour and set. pour the mixture into cute silicone molds or a shallow glass dish. let it cool to room temperature, then refrigerate for 2-3 hours, or until set.
cut or unmold. if you used a dish, slice the gummies bite-sized squares. if you used molds, simply pop the gummies out.
enjoy. store the gummies in an airtight container in the fridge for up to 1 week.
why it works for glowing skin:
• Gelatin (collagen) improves skin elasticity and hydration
• Vitamin C (from orange/lemon juice) helps boost natural collagen production
• Green tea/matcha reduces inflammation and provides antioxidants
ive been loving making these, and I feel like it has improved my skin by a lot (especially my dark circles????), so I felt like sharing this fun little recipe with you guys. <3
my insta @ malusokay
#malusokay#girl blogger#askmalu#coquette#it girl#pink blog#that girl#aesthetic#dream girl#pink pilates princess#girly stuff#girlblogging#just girly things#hell is a teenage girl#gaslight gatekeep girlblog#this is a girlblog#girlblog aesthetic#gaslight gatekeep girlboss#girlblogger#glow up journey#glow up#glowingskin#skincare routine#skincare#recipes#collage#healthyskin#healthylifestyle#self care#beautytips
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lets talk skincare⋆.ೃ࿔*:・🎀
disclaimer i am NOT a dermatologist so to create this post i did LOTS of research and i'll link all of my sources at the end of the post. i just wanted to kind of put everything that i found in here so i hope its helpful 💕🗒️
HOW TO DETERMINE UR SKIN TYPE ;
wash ur face with a gentle cleanser, pat dry and wait for about 30 minutes. if ur skin appears shiny throughout then u have oily skin, if ur skin appears tight/flaky then u have dry skin.
if u notice a slight shine on your nose and forehead then you have normal skin. if you have a combination skin type, then the skin will get oily around the t-zone.
INGREDIENTS TO LOOK FOR ;
for skin with acne -> salicylic acid, benzoyl peroxide, sulfur and mandelic acid.
for dry skin -> lactic acid, hyaluronic acid, ceramides and glycerin.
for pigmented skin -> mandelic acid, niacinamide, vitamin C, and arbutin.
INGREDIENTS THAT U SHOULD NOT MIX ;
mixing retinol and vitamin C causes irritation, mixing vitamin C and glycolic acid results in over-exfoliation, mixing AHA and retinol causes extreme dryness.
INGREDIENTS THAT U SHOULD MIX ;
hyaluronic acid + ceramides = repairing skin barrier. niacinimide + salicylic acid = healing acne. retinol + niacinimide = collagen production.
GLOWY SKIN TIPS ;
use a cleansing balm to cleanse ur face to remove all the impurities from ur skin
use serums to hydrate ur skin
lather on moisturizer, dont put too much to the point where ur skin cannot produce its own oils, but you MUST moisturize
apply sunscreen everyday, not only on ur face but also on ur neck and hands
face masks 1-2x a week
get enough sleep, drink enough water, and steer clear of overly processed foods
SKINCARE DOESNT STOP AT UR CHIN ;
its important to take care of the skin on ur neck for SO many reasons because skincare doesnt stop at ur chin. ur neck reflects the first signs of aging, and its most susceptible to sun damage so show it some love!
use the same products that u use on ur face on ur neck also, moisturize ur neck and always apply sunscreen, lastly, use some retinol to build collagen.
HOW TO APPLY RETINOL ;
when applying retinol, use a pea sized amount. avoid application around ur eyes and the openings in ur nose, and use retinol in ur night skincare routine only.
HOW OFTEN TO USE SKINCARE ;
retinol should be used nightly (1-2x a week for beginners). hyaluronic acid should be used (2x a day). salicylic acid should be used (1-2x a week). sunscreen should be applied daily, no need to apply it at night and if u can, you should reapply it every 2-3 hours. vitamin C (1x a day in the morning).
SERUMS FOR UR SKIN-TYPE ;
for oily skin use -> salicylic acid, niacinimide and mandelic acid.
for dry skin use -> hyaluronic acid, ceramides and lactic acid.
for normal skin use -> vitamin C, glycolic acid, and retinol.
for aging skin use -> peptides, retinol and vitamin C.
for acne prone skin use -> salicylic acid, retinol, and niacinimde.
for combination skin use -> mandelic acid, niacinimide, and glycolic acid.
WHAT TYPE OF FACEMASK IS BEST FOR YOU ;
cream masks are good for all skin-types and it soothes and moisturizes. clay masks are good for oily or acne prone skin and it absorbs oil and controls shine. charcoal masks are good for oily or acne prone skin, and it deep cleanses and unclogs.
sheet masks are good for all skin-types, it nourishes and hydrates. enzyme masks are good for all skin-types and it gently exfoliates and brightens the skin. bubble masks are good for all skin-types and it hydrates and soothes.
gel masks are good for all skin-types and it provides a cooling effect. exfoliating masks are good for all skin-types BUT if u have sensitive skin then exfoliating masks are not for you. exfoliating masks remove dead skin cells and debris.
HOW TO LAYER UR SKINCARE ;
in the morning (cleanser + toner + hydrating serum + vitamin c + moisturizer + sunscreen) in the evening (double cleanse + toner + hydrating serum + retinol + moisturizer)
#advice#honeytonedhottie⭐️#it girl#becoming that girl#self care#that girl#self love#it girl energy#dream girl tips#dream girl#dream life#tips#guide#hyper femininity#girl blogging#hyper feminine#skincare#skincare routine#skincare guide#pampered princess#diva#luxurious#glamor#doll
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also, do you know any other fun proteins where the amino acids react with eachother to form a new chemical? like residues 65-67 in GFP cyclysing to form the chromophore?
to start, i had a bit of a hard time finding the right search terms for this question, and a lot of what i found is more focused on synthetic or enzymatic methods used in labs, rather than lists of natural examples. if anything is wrong or missing as always pls lmk! i rambled a lot so that info is going to get hidden under the cut, but here is the tl;dr of three relevant PTMs
one takeaway I had from trying to find things is just how unique GFP actually is! it has been important enough for studying biological systems that its discovery was awarded the nobel prize in 2008, and a lot of incredible chemistry went into modifying its structure to make other fluorescent proteins in different colours. this is important if you want to look at more than one thing by fluorescent microscopy, and was done by altering residues around the chromophore to influence its protonation state/pKa through the local environment.
disulphide bonds:
so many proteins: insulin. RNAse A. chymotrypsin. etc.
isopeptide bonds:
the collagen-binding domain of S. aureus Cna and probably several bacterial pili have intramolecular isopeptide bonds
Vibrio cholerae, which causes cholera, makes isopeptide bonds to cross-link actin in its host
there are more examples of isopeptide bonds on wiki
biaryl ethers:
a lot of these are not made by ribosomes, and it looks like all of them are fairly small and funky looking peptides, but i think that has to count at least a little bit. here are a couple:
patellamide A
telomestatin (the wiki page on this one is so short and as far as i could tell, we aren't even sure yet if this is made by ribosomes or not so i'm really pushing things here on what counts)
letter sequence in this ask matching protein-coding amino acids:
alsdyknwanytherfnprteinswheretheaminacidsreactwitheachthertfrmanewchemicallikeresidesinGFPcyclysingtfrmthechrmphre
protein guy analysis:
for all the time i spent on this post, the protein itself is kind of underwhelming. its a shorter one with three alpha helices and a small, two strand antiparallel beta sheet, with some loops in between. this could be a real peptide, or it could just be the confused ramblings of an algorithm trying to make shapes out of an input. the confidence score is pretty low, so as usual my bet would be on the latter option, but who knows? maybe this could stably exist in real life? dream big and all that
predicted protein structure:
the main keyword i was using was 'protein cyclization', so i'm sure i missed a lot, and most of what i found is focused more on synthetic methods, but i was still able to get some good information.
this first article here gives a nice overview of protein cyclization, and a lot of different and super neat ways it can be done. if anyone wants me to give a more detailed breakdown of this article i would be happy to, since i'm not sure how clear it is to people without much of an organic chemistry background.
this next article gives an overview of post translational modifications, and also looks like a good resource with a lot of information. there are so many different PTMs out there, so if you'd like me to discuss one in particular a little more, let me know as well.
this gave me a few specific PTMs to find examples of.
the first and most obvious is disulphide bonds, which are what you are describing, but far less unique, so i also want to give some other examples
another example is isopeptide bonds, which are formed between an amine and carboxyl group just like a regular peptide bond, except that these amine and/or carboxyl groups are part of the side chain, not the peptide backbone
and finally, i found biaryl ethers, which i had never actually heard of before, and are only made by microbes and scientists, and are interesting for pharmaceuticals
there are more examples that involve cyclization with the backbone, and other types of PTMs beyond cyclization, but i've already spent too long on this, so if you want something more specific then you have to ask for it
#science#biochemistry#biology#chemistry#stem#proteins#protein structure#science side of tumblr#protein asks#protein info
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Revitalize Your Skin with Collagen Peptide Serums
Introduction:
Embark on a journey to radiant and revitalized skin with The Phix. This article explore into the transformative power of Collagen Peptide Serum and peptide facial serum, a dynamic duo crafted for ultimate skin renewal. Discover the science behind peptides, collagen, and Vitamin C, and how this combination becomes the cornerstone of your skincare routine.
Elevating Your Skincare with The Phix:
The Power of Collagen Peptide Serum
Uncover the magic of The Phix Collagen Peptide Serum. Delve into how peptides stimulate collagen production, promoting skin elasticity and reducing the appearance of fine lines and wrinkles. Learn why this serum is a vital component in achieving a firm, youthful complexion.
Vitamin C Peptide Serum: The Radiance Solution
Explore the benefits of The Phix peptide vitamin c serum. From brightening your complexion to acting as a powerful antioxidant, understand how Vitamin C contributes to a radiant and healthy skin tone. Discover the dual action of collagen and Vitamin C working harmoniously for skin perfection.
The Perfect Harmony: Collagen and Vitamin C Peptide Serum
Why The Phix Peptide Serums:
Unmatched Quality and Efficacy
Explore The Phix commitment to quality and efficacy in skincare. From sourcing premium ingredients to the meticulous crafting of each serum, understand why The Phix Peptide Serums are unparalleled in delivering transformative results.
Daily Rituals with Collagen Peptide Serum
Incorporate The Phix Collagen Peptide Serum into your daily ritual and witness the transformative effects. This section provides insights into the ideal application, emphasizing its lightweight texture that absorbs effortlessly into your skin. Learn how to make this serum a staple, creating a foundation for a radiant and resilient complexion.
Vitamin C Peptide Serum: A Burst of Freshness Every Day
Explore the refreshing burst of The Phix peptide vitamin c serum. Understand the optimal usage, whether as a revitalizing morning boost or a rejuvenating nighttime treat. This section highlights the versatility of the serum, ensuring that you can infuse your skin with Vitamin C goodness at any time for a continuous, radiant glow.
The Phix Promise: Radiant Skin, Every Serum Drop
Dive into The Phix commitment to radiant skin. From the careful selection of ingredients to the advanced formulations, grasp the essence of The Phix Promise. Every drop of Collagen Peptide and Vitamin C Peptide Serum is designed to contribute to your journey of achieving radiant, youthful, and revitalized skin.
Elevate Your Beauty Ritual with The Phix:
Collagen and Vitamin C Peptide Serum Experience
Immerse yourself in the experience of using The Phix Collagen Peptide and peptide vitamin c serum together. This section explores how this dynamic duo enhances each other's benefits, providing a comprehensive solution for a radiant and healthy complexion. Discover the joy of a skincare routine that truly elevates your beauty ritual.
Conclusion:
In conclusion, The Phix Collagen Peptide and peptide facial serum redefines your skincare journey. Elevate your routine with the power of peptides, collagen, and Vitamin C, unlocking the secret to radiant, youthful, and revitalized skin. Embrace The Phix promise of quality, efficacy, and the beauty that radiates from within.
#collagen peptide serum#vitamin c peptide serum#peptide vitamin c serum#peptide facial serum#phix philler#the phix philler#the phix#the phix filler#phix philler peptide#phix philler peptide serum
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Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategy - Published Sept 21, 2003
Yes, you are reading that date right
Never let them tell you "we didn't know the risk." They knew. They just ignored all epidemiological best practices. For corporate profit.
Abstract Background Severe acute respiratory syndrome (SARS) is a febrile respiratory illness. The disease has been etiologically linked to a novel coronavirus that has been named the SARS-associated coronavirus (SARS-CoV), whose genome was recently sequenced. Since it is a member of the Coronaviridae, its spike protein (S2) is believed to play a central role in viral entry by facilitating fusion between the viral and host cell membranes. The protein responsible for viral-induced membrane fusion of HIV-1 (gp41) differs in length, and has no sequence homology with S2. Results Sequence analysis reveals that the two viral proteins share the sequence motifs that construct their active conformation. These include (1) an N-terminal leucine/isoleucine zipper-like sequence, and (2) a C-terminal heptad repeat located upstream of (3) an aromatic residue-rich region juxtaposed to the (4) transmembrane segment. Conclusions This study points to a similar mode of action for the two viral proteins, suggesting that anti-viral strategy that targets the viral-induced membrane fusion step can be adopted from HIV-1 to SARS-CoV. Recently the FDA approved Enfuvirtide, a synthetic peptide corresponding to the C-terminal heptad repeat of HIV-1 gp41, as an anti-AIDS agent. Enfuvirtide and C34, another anti HIV-1 peptide, exert their inhibitory activity by binding to a leucine/isoleucine zipper-like sequence in gp41, thus inhibiting a conformational change of gp41 required for its activation. We suggest that peptides corresponding to the C-terminal heptad repeat of the S2 protein may serve as inhibitors for SARS-CoV entry.
#covid#mask up#pandemic#covid 19#wear a mask#coronavirus#sars cov 2#public health#still coviding#wear a respirator#long coivd
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Can you mix retinol with vitamin C? What about exfoliants and niacinamide? As a board-certified dermatologist and skincare formulator, I break down the science behind combining active ingredients, debunk common myths, and reveal which combinations work (and which don't). Learn how to layer your skincare effectively, understand the importance of timing and pH levels, and discover why some popular combinations might sabotage your results.
🎯 Topics Covered:
Vitamin C and retinol combinations Exfoliants with active ingredients Benzoyl peroxide and retinol interactions Copper peptides with vitamin C Niacinamide myths debunked pH levels and absorption timing Barrier protection importance How to introduce new skincare actives Signs of skin irritation Best practices for layering
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