#💊kill

[joejoeba]

[illsadboy]

Mi vorrebbero trascinare in clinica per farmi curare ma non esiste medicinale se nel bene vedo sempre il male.

[anchor-dreamss]

miss you everyday little brother, Jeff Hedger 🩷

[0the-anomaly-system0]

jericho? more like chairicho.

[godblooded]

if i leave with gloria in my pocket tomorrow well i won’t be surprised.

[dingdongdoodilydoodilydoo]

Mommy and the middle child having something special? Unexpected-

...shut up all we do is eat food and vent

[darthteeth]

URGENT!!!Help Abdul Salam Al-Anqar and his family get through this war in Gaza!!!

(URGENT) THEY ARE AT €3,445 OUT OF €50,000 GOAL

I was asked by @nader5555 to make this, if u cannot donate please please share this post. Copy pasted from a message i was sent:

"Only a Few Hours Left Before We Enter Our First Year of War, Genocide, Starvation, and Displacement A Final Plea from the Heart of Hell: Save Us Before Hope Dies 💔🔥 I am Abdel Salam, and I have nothing left but words written by a trembling hand ✍️. The war has not only destroyed our lives; it has taken everything from us. Our home, which was once our refuge, is now a pile of rubble 🏚️.

My car, my only source of livelihood, was destroyed in a sudden strike 🚗, and the work that sustained us is now a distant memory 💼. Today, I live in an endless nightmare. Under a sun that burns everything in its path 🌞🔥, my family and I sit in a worn-out tent, a tent that shields us neither from the summer heat nor the winter cold ❄️. Insects 🦟 invade the place, diseases consume our bodies 🩺, and my younger siblings cry from hunger and thirst 🍞💧. We have no clean water or a crumb of bread to ease our hunger. Each passing day deepens the weight of this hell we live in.

My Daughter Eman is Dying from Malnutrition 😨 My daughter Eman suffers from malnutrition; I have nothing to feed or treat her with. The deterioration of her health is killing me slowly. Every glance in her eyes, every pain she endures, crushes my heart 💔. How can I explain to her that what was once our hope has now turned into nothing but a mirage? The Night Only Adds to Our Pain 🌙 The night does not bring us rest; it only adds to our pain. We sleep on hard ground, feeling the cold in every bone of our bodies 🥶, with nothing but pieces of cardboard 📦 to cover us. My wife Aya cries in silence 🥺 as she watches our daughter’s future fade before her eyes. My mother Eman suffers from illness and needs urgent medical care 🩺💊.

My Father Ahmed is Sick with Cancer and Needs Emergency Treatment My father Ahmed, who is sick with cancer, needs emergency treatment outside Gaza, and the cost of his treatment is at least $10,000, not including accommodation. As he suffers from severe pain, I cannot provide the treatment he needs due to our dire situation.

My Siblings Are in Constant Suffering ⚰️ My brother Omar was unable to continue his studies due to the situation. My brother Nader could not take his high school exams, and my younger brother Mohammad suffers from brittle bones and needs treatment we cannot afford. Every day we live brings us one step closer to the end. Death surrounds us from every side: if not from hunger 🍽️, then from illness 🦠. And if not from illness, then from the despair that devours our souls. Where is Humanity? Where is the World? 🌍💔 We want to leave the devastated Gaza Strip to escape the machinery of destruction and killing and the severity of hunger and poverty. The cost of travel for each person is $5,000, and we are a family of seven members, bringing the total cost to $35,000.

Where are the compassionate hearts? Are you waiting for us to disappear into the depths of this suffering? Are you waiting until death takes us before you act? We are drowning, and we don’t have enough strength to scream for help 🆘. Will you let this cry go unanswered? 😭 Your donation today is our last thread of hope. With the little support I received, I was able to buy a simple phone 📱 to reach out to you. But the bitter truth is that what I and my family need is much greater. We are not asking for much; just enough to save our lives from this hell 🔥. Every donation, no matter how small, could be the difference between life and death for us 👐. Don’t Let Us Disappear in the Darkness of Suffering 🌑 Don’t let our story end here. Be the light that guides us to salvation 🕯️✨.

With every tear, with every pain, I write this final plea to you, Abdel Salam."

taglist

@butchniqabi @xinakwans

@batekush

@appsa

@nerdyqueerr

@butchsunsetshimmer

@biconicfinn @stopmotionguy

@t4tvampireisms

@strangeauthor

@bryoria @shesnake

@legallybrunettedotcom

@lautakwah @sovietunion

@neechees @evillesbianvillain @antibioware

@akajustmerry @dizzymoods

@ree-duh @neptunerings

@explosionshark

@heritageposts

@ibtisams

@schoolteacher

[xtruss]

HIV Cure Nearer With Way To 'Shock And Kill' Latent Virus

— Published March 27, 2024 | Newsweek

A Stock iIlustration Shows the Human Immunodeficiency Virus. Researchers May Have Found a Way to Remove Latent HIV From Cells, According to a New Study. IStock/Getty Images Plus

We might be a step closer to curing HIV, as researchers have developed a way to knock out a version of the virus lurking in the body.

Using something called an HIV-like particle (HLP)—which are dead HIV particles containing HIV proteins that trigger an immune response in a patient—may help treat the disease, scientists from the University of Western Ontario's Schulich School of Medicine and Dentistry and the U.K.'s University of Bristol reveal in a paper in the journal Emerging Microbes & Infections.

HLP was found to be 100 times more effective at treating the virus in people living with chronic HIV while on combined antiretroviral therapy (cART) than other candidate HIV cure therapeutics.

HIV, or human immunodeficiency virus, attacks the immune system, specifically targeting CD4 cells, which are crucial for helping the body fight infections and diseases. Without treatment, HIV can progress to the more advanced stage called AIDS, which can lead to death in only a few years.

More than 1.2 million people across the U.S. have HIV, with over 30,000 new cases diagnosed every year. There is no cure for HIV, but several treatments are available that can allow patients to live a long life.

HIV is treated primarily with cART, which is a combination of medications designed to suppress the replication of HIV in the body. This therapy works by targeting different stages of the HIV life cycle, preventing the virus from multiplying and reducing its levels in the bloodstream.

The goal of cART is to reduce the viral load (the amount of HIV in the blood) to undetectable levels, allowing the immune system to recover and preventing the progression of HIV to AIDS. However, cART doesn't completely eliminate the virus from the body, and the virus creates a "latent reservoir" where it hides within the cells of the body, lying dormant.

According to the new paper, HLP can help to purge cells of this latent HIV, making it a major step forward in treating and curing the infection.

"The development of this HIV cure was ten years in the making but with strong support from our collaborators in the US, Canada and Uganda, we have observed a striking ability of HLP to drive out the last remnants of HIV-1, which we hope will provide an affordable cure for all," said Eric Arts, the Canada research chair in HIV pathogenesis and viral control at the Schulich school, in a statement.

"To live HIV-free is a goal for the 39 million infected. It is also the priority of the UN and WHO to end the HIV pandemic by 2030," he added.

HLP, a deactivated version of HIV, contains various proteins that make it recognizable to the body as the virus, triggering an immune response. But it doesn't contain any of the structures that make the virus harmful and immunocompromising. HLP can therefore trigger the immune system to go hunting after HIV viruses remaining in the body, including the latent viruses hidden inside the immune cells. This allows the body to "shock and kill" the hidden viruses, the researchers said in the paper.

The researchers used blood samples from 32 patients with chronic HIV from the U.S., Uganda and Canada who had been on stable cART for a median of approximately 13 years. They found that HLP was able to specifically target just the immune cells containing a latent HIV reservoir, removing the virus from the cells.

"Over time, the virus grows more diverse within a single individual that is not on treatment which makes it more difficult to target," co-author Ryan Ho, a master's student at the Schulich school, said in the statement. "This formulation we've crafted covers the theoretical diversity so it can reach the HIV-1 in all those people living with HIV."

This is an extremely exciting discovery for HIV researchers, as it could be combined with cART and one day lead to the total elimination of HIV from the bodies of patients.

Minh Ha Ngo, the paper's lead author and a postdoctoral scholar at the Schulich school, said in the statement: "One concern expressed among people living with HIV for years is that continued use of cART could lead to the virus becoming unreachable and unable to be eliminated.

"The results of this study, by contrast, demonstrate that combining HLP with cART is still able to trigger the latent reservoir, even in chronic cases. If these dormant latent reservoirs can be awakened, then they can be eliminated from the body," Ngo said.

Additionally, HLP appeared to work on all variants of HIV from around the planet, indicating that it could be successful at treating even mutated versions of the virus.

"Owing to its high mutation rate, HIV exhibits remarkable genetic diversity, resulting in different viral subtypes, some of which predominate in particular regions of the globe," said Jamie Mann, a senior lecturer in vaccinology and immunotherapy at the University of Bristol's Veterinary School, in the statement.

"We were excited to see preliminary evidence that our HLP cure therapy reverses latency irrespective of the subtype of the individual's infection. Whilst this needs to be explored further, it hints at the global applicability of our approach," Mann said.

The researchers hope to test this HLP treatment across a larger cohort of people around the world to determine if it is an effective treatment strategy for those with both chronic and acute HIV.

— Jess Thomson is a Newsweek Science Reporter based in London UK 🇬🇧

[destroyingangelneveragod]

"kill em with kindness" wrong potion of transexuality

🏳️‍🌈💥💫🧑‍🔬🎊🎉🪄🧪⚗️💊⚧️♀️♂️❓✔️🏳️‍⚧️

[blanksoullesseyes]

[dakotac0le]

my dealer niklaus: got some straight gas 🔥😛 this strain is called “accent changing weed” 😳💊

me: yeah whatever i dont feel shit

5 min later: top o the mornin to ya. got a cuppa ? 🇬🇧💂‍♂️

my buddy felipe, pacing: ive got to kill gillion

[kisses4reid]

masterlist 💋

❣️- fluff

🥀- angst

💊- comfort

spencer reid

❣️convenient (2 3 4 5) - studying while working at a convenience store is helpful when a regular happens to be a genius

❣️big change - you cut spencer’s hair, the close proximity makes you nervous, and his new haircut makes him confident

❣️🥀 missed it - every forgets your birthday except spencer

❣️ missed it (part 2) - garcia remembers and scolds the team for forgetting

❣️🥀 criminally hot - reader gets falsely accused and spencer has to expose your relationship to clear you

❣️🥀 untitled - rejecting spencer’s confession because of insecurity, and spencer convincing you his love is real

❣️ protect - reader’s pregnant, and a trip to the hospital ruins the surprise

❣️🥀 understand? - reader is a translator, spencer is fascinated with her intelligence (part two here)

🥀 untitled - killing your kidnappers and spencer finding you

❣️untitled - ballerina!r x downbad!spencer

❣️sleep talking - reader sleep talks, spencer keeps you close

❣️cuddles - reader’s and spencer’s daughter has a nightmare

❣️not our scene (part 1) - an undercover mission creates and dissipates distance between you and spencer

❣️not our scene (part 2) - an undercover mission creates and dissipates distance between you and spencer

❣️🥀scare (part 1) (part 2) (part 3) - you’re with someone else, and you have a pregnancy scare

💊🥀 type O - reader gets hurt in action

aaron hotchner

💊🥀 untitled - stressed with red hands under an all too bright bathroom, your panic attack is avoided with the help of your boss (WARNING: mentions of blood)

💊❣️red tissues - you get nose bleeds regularly, aaron learns when you’re about to have one, comfort ensues (WARNING: lots of blood and mentions of severe sickness)

❣️ruined surprises - you find a small velvet box in one of aaron’s drawers

❣️date night - you come home drenched to a forgotten date with aaron, but he doesn’t mind

[rileys-battlecats]

micaclan tumblr dash simulator

☁️ the-fluffiest-puddle follow

I cannot believe the things my friends talk me into. on an unrelated note where can you hide a baby coyote

#puddletalks #seriously where did they find that thing #and WHY did they keep it??

(3 notes)

⭐️ larkstar-unofficial follow

if you catch prey and eat it before bringin anything back to the clan i'll kill you on sight <3 many such cases, unfortunately

🌠 larkstar-official follow

Laureltail I know this is you. I've told you twice now to delete this blog. Meet me in my den this evening, we're having a talk

⭐️ larkstar-unofficial follow

chat i think im going to die tonight

#remember me #never forget my sacrifice

(24 notes)

🐆 speckled-trees-and-autumn-leaves follow

people looove to ask me "oh birchspeckle tell me the future, will the clan thrive this greenleaf, will i find a mate that loves me" but then the SECOND i tell them the exact time and date of their death suddenly I'M the bad guy?? like ok sweaty you're the one that was after forbidden knowledge you don't get to be choosy about what you learn

#justmedicinecatthings #seriously they get so upset when they learn this stuff like. how do you think i feel? #i just gotta sit on this information forever? im not allowed to vent?? #this is why i never hang out in the camp smh

(1 note)

🐦‍⬛ muddy-paws follow

anybody else finding the torment relentless

(0 notes)

💊 owlpounce-official follow

This is your reminder to stretch before partaking in any strenuous activity! The best way to stay healthy and happy is to take steps to avoid being hurt in the first place. Stretching first may seem like a waste of time, but I promise it's much better to spend a few minutes stretching your legs before hunting than to spend a few days in the medicine den recovering from a pulled muscle!

#PSA #selfcare #safe practices

(15 notes)

🍐 having-a-peary-good-day follow

I don't want to name any names, but I feel like we as a clan have an issue with delegation of labor when it comes to the care of our most vulnerable members. Watching the kits is all well and good, but as the only current queen in the nursery right now, I find myself doing so much repair work for the den walls all by myself. Nominally, our apprentices ought to be doing much of this work, but quite frankly, our 'paws simply don't have the necessary experience to fix the more delicate areas, and I have ended up redoing much of their work myself. This isn't to disparage our apprentices, they've been doing their best, but I have ideas as to how we might better address these issues as a clan.

Keep reading

#genuinely I think we could be doing this so much more efficiently #like I understand that the 'paws need the learning experience #but not at the cost of our kitten's warmth and safety #you know? #and that's not even mentioning the elder's den

(7 notes)

💫 swooping-hawk-rising-star follow

fffksnkd. Ssssssksdjsj,,,,,,,,,,,,,,,,,,,,,,,,,,,,h

🪷 white-tipped-tail follow

You ok, Hawkpaw?

💫 swooping-hawk-rising-star follow

COYOTE PUP ON MY KEYBOARD

#HELP

(4 notes)

🦊 foxjaw-official follow

The dawn patrol spotted bear tracks this morning just past the northeastern border, near the old hemlock tree. The tracks were old, and did not lead into Micaclan territory. Be that as it may, remember to remain on guard, and to travel in groups of 3 or more until it can be confirmed that the bear has not remained close by.

#PSA #patrol reports

(15 notes)

🏞️ gullys-tuft follow

Why is Sandleap retching into the bushes

#should i really be asking? #do i even want to know?

(2 notes)

🌸 resting-on-your-laurels follow

gonna stuff a frog inside a squirrel for my morning meal. surf and terf

🌸 resting-on-your-laurels follow

dont do this

🔥 embers-and-sparks follow

you can't tell me what to do

🔥 embers-and-sparks follow

dont do this

🏜️ pocket-sand follow

It can't be that bad!

🏜️ pocket-sand follow

dont do this

#the texture #its so bad #i dont want to waste prey but. i dont think i can swallow this #not pogchamp

(13 notes)

—————————————————————————

[tjwritesfanfics]

Every Universe NSFW Masterlist 🌌❤️‍🔥

A collection of burbs where you fuck MGG in every universe.

Note that all of these are smut.

Will not be written in order. Written as inspiration comes.

Ones that are left blank plz feel free to suggest stuff!

Main Masterlist | Every Universe SFW Version

Universe One: Criminal Minds (Spencer Reid) 👓

Title: Texts messages

Summary: Spencer is not happy with your choice of texts while he’s away.

Universe Two: 68 Kill (Chip Taylor) 💰

Title: Mine to use

Summary: After being a toy for everyone, Chip wanted a toy of his own.

Universe Three: Trash Fire (Caleb) ⛪

Title: Oh Goddess

Summary: There was only one thing that tempted Caleb away from his faith and that was you.

Read Here

Universe Four: Zoe (Micheal) 💊

Title: For the (actual) first time

Summary: You and Micheal have sex for the first time without the effects of Benysol.

Universe Five: RV (Joe Joe) 🚙

Title: Popsicle

Summary: Joe Joe wonders just how skilled you are with your tongue.

Universe Six: Beginner's Luck (Franklin) 🎳

Title: BabyDoll

Summary: It wasn't easy to love Franklin, but you were tired of trying. He just didn't seem to be done with you.

Universe Seven: Life after Beth (Kyle Orfman) 🧟

Title: Prom Night

Summary: You couldn't stand Kyle Orfman, but for some reason you couldn't stand it when others picked on him more. You save your enemy from prom night and also make an interesting proposition.

Universe Eight: Band of Robbers (Joe) 💪🏻

Title: Suggest a title!

Summary: Suggest a concept!

Universe Nine: King Knight (Thorton Adams) ✝️

Title: Let's start a cult family

Summary: Thorn was really wanted kids. Maybe more than you realized.

Universe Ten: Excision (Mr. Claybaugh) 👨🏻‍🏫

Title: A+

Summary: You were willing to do anything to get an A in Mr. Claybaugh's class

Universe Eleven: Magic Valley (Mok) ⛓️

Title: Let me help you

Summary: When Mok was having a hard time getting off, you, his best friend, decide to help him despite his (very weak) protests.

Universe Twelve: 500 Days of Summer (Paul) ☀️

Title: 500 days of tennis

Summary: Paul thought Robin was his end game until he met the cute tennis coach.

Universe Thirteen: Babyface (Wes) 🐈‍⬛

Title: Merry Christmas to me

Summary: It's you first Christmas with your boyfriend, Wes. And his gift of a collar may be more for him than for you.

Universe Fourteen: Hot Air (Lesley) 🎈

Title: Marry me Mr. Stranger

Summary: After a wild night in Vegas, you wake up married to a very attractive, yet terrified, stranger. After getting to know him all over again, maybe you could see yourself staying with him.

Universe Fifteen: Desire (James) 🔥

Title: More than the screen

Summary: James seemed to like his costar than he let on and the sex scene seemed more real than EITHER of them let on.

Universe Sixteen: Beautiful Girl (Ziggy) 📹

Title: My girl my camera

Summary: Once Ziggy meets famed camgirl, he has to film her.

Universe Seventeen: How to be a serial killer (Bart)🔪

Title: Sweet but psycho

Summary: Bart never thought he would find anyone else that would share in his… lifestyle, but there you were, covered in blood and knife in hand.

Universe Eighteen: The life aquatic with Steve Zissou (Nico)🌊

Title: Rocking the boat

Summary: It can be lonely out at sea. Thankfully you have the new cute intern to keep your company.

Universe Nineteen: Suburban Gothic (Raymond) 👻

Title: On the way out

Summary: On your last day in town, you decide there is one last thing you want to do. Or well someone.

[k1tkatzzz]

“kill em with kindness” wrong!! get squipped 💊💊💊💊💊💊💊💊💊💊💊💊💊💊💊 💊💊💊💊💊💊💊💊💊💊💊💊💊💊💊 💊💊💊💊💊💊💊💊💊💊💊💊💊💊💊 💊 💊💊💊💊💊💊💊💊💊💊💊💊💊💊💊 💊💊💊💊💊💊💊💊💊💊💊💊💊💊 💊💊💊💊💊💊💊💊💊💊💊💊💊💊💊 💊💊💊💊💊💊💊💊💊💊💊💊💊💊💊 💊💊💊💊💊💊💊💊💊💊💊💊💊💊💊 💊💊💊💊💊💊💊💊💊💊💊💊💊💊💊 💊💊💊💊💊💊💊💊💊💊💊💊💊💊💊

[dingdongdoodilydoodilydoo]

What do you think of Ghost (the band)?

ohhh you meaj the 8 fucking oerson band run by a swedish man who hires and replaced people constantly?

a bunch of oussies in masks, the only song i like js Jigolo Har Megiddo