#vladimir demikhov

[zooophagous]

Your post is how I learned about Vladimir Demikhov, his work was absolutely fascinating. I mean it’s unethical but I love it

Fascinating yet unethical describes a decent portion of medical science

[neutral-milk-hotel-mood-board]

The results of one of Vladimir Demikhov's experiments. A "two headed boy"

[the-helixverse]

Villain Profile: Iron Lung

The emergence of posthumans in 1951 brought with it a new revolution in biotechnology. Many prominent scientists, psychologists, biologists, physicians and others sought to use these to their fullest potential. One of them was Dr. Julius Leichtenberg.

Born in Hesse in 1937 and later immigrating to the UK, Leichtenberg was an aspiring neurosurgeon who attended the University of Oxford. His biggest influences were American neurosurgeon Robert White and Soviet organ donation pioneer Vladimir Demikhov.

Leichtenberg was fascinated by the idea of head and brain transplants, and believed it was possible to utilize this technology to save lives, whether it was preserving the brain or attaching it to a new body, either natural or artificial. The procedure had yet to be performed on a human and Liechtenberg and others were looking for willing subjects.

However, it was during this search that Leichtenberg, along with several other bystanders, were gravely injured in a fight between a posthuman criminal and police in the streets. The collateral damage left him so badly injured that being rendered quadriplegic was the best case scenario. It was more likely he would not survive.

Already a rather bitter man after facing criticism for his support of brain transplants, Liechtenberg's embitterment turned to spite and he decided to volunteer for his own work. With the help of thoroughly detailed notes and several assistants, he had his brain removed and preserved in solution and attached to a set of artificial sensory relays.

It would've been easy enough for Liechtenberg to simply find a donor body or have one grown for him and move on from there. But, after spending days, weeks and months fixating on his resentment- as well as possible unexpected psychological effects of being an isolated brain- he opted instead to pursue revenge.

The full details of what happened afterward is unclear, but Liechtenberg opted to have his brain preserved in a blast-proof canister and encased in an artificial body, which was then armed with various weapons and means for destruction. Early models were large, clunky and mechanical, which is where he earned his moniker in the press: "Iron Lung."

Iron Lung's primary M.O. is targeting posthumans, particularly those who try to use their abilities to make the world a better place, and either killing them or mutilating them to the point where they can no longer use them. He's shown no qualms about doing the same with other philanthropists, leaders, law enforcement or anyone else who gets in his way.

After numerous skirmishes, he's also gradually adapted his artificial bodies, upgrading them with new and better technology, weapons and equipment. He has now become a large, snake-like figure with a highly flexible body composed of synthetic muscle. He's also learned and employed a great deal of tactical skill, showing both proficiency in combat and the willingness to retreat when overwhelmed.

To date, no one has ever been able to capture him. The most that can be done is to cause him enough harm to force him to retreat and repair himself. With the only vital component of him being his brain, which is always hidden behind several layers of protection, the damage he can take is staggering. Efforts to stop him have gone so far have included RPGs, a Lockheed AH-56 Cheyenne and an FV4201 Chieftain tank.

He also possesses and artificial voice that retains his native accent, and while it sounds disturbingly even throughout (comparable to HAL 9000), the more damage he takes, the more this voice distorts until it devolves into a loud series of electronic whirs and blaring.

Because of the viciousness of his attacks and the nature of his existence, head and brain transplants remain a contentious subject, although a handful have been performed in the years between Iron Lung's emergence.

[no-meat-no-pudding]

I've been thinking a lot about animal testing and moral dilemmas lately. Moreso the latter than the prior, recently. Everything I do require cross examination, or so it feels.

As far as animal testing goes, I think it's as depraved as any other practice of holding sentient beings prisoner, and experimenting on them. I understand it is medically necessary (though I fully resent any testing done for the sake of vanity, such as makeups and perfumes) but of course that's a difficult pill to swallow.

I think if someone I cared about needed saving, I'd let a scientist torture and vivisect any number of people (of any species) to do so. I don't claim to be above hypocrisy, and I'm aware many would feel the same way, and I don't think it would be fair to deny them that research and that opportunity. Not that I think the medical industry is necessarily fair - I think there's plenty of profit incentive to not find an actual cure for diseases like cancer or HIV, and so we are not likely to ever see that (at least widespread.)

Another note on my own hypocrisy - I sometimes see people bemoaning the fate of Laika, cursing her handlers. I disdain them for this, I'll be honest. It's hard to feel they care about her for any reason other than her charismatic species. They don't owe me anything, though, and I'm not superior for preferring apes and rodents and bugs. Sighs. This is very stream of consciousness. On that note, I think people are especially unfair to Vladimir Demikhov, who did head transplants on dogs. As grotesque as that may seem (and is) he's responsible in part for your grandmother surviving that heart transplant, and I'm sure he didn't set out to torture dogs for no reason but to upset you, he answered a sort of trolley problem question, as one does for progress.

I wonder what the modern state of animal testing is. I need to look into this. It's been a while, I used to research this a lot as a child, and make myself sick. I remember pouring over books released by PETA and staring at the glossy photos inside of animal carcasses being held by blond models.

I wonder if it's worth it to know. What good would that do? Sometimes I feel I should bare the weight of knowing as a duty, or act of compassion, but what and who does that actually help, besides hurting me? The world's most ineffective martyr. Still, it feels irresponsible not to seek this information out. Ignorant, ungrateful even. Ugh. Oh - speaking of useless endeavors, I need to register to vote now that I've moved.

This went nowhere fast, but at least I made the animal testing post that's been stewing away in my brain for the past several weeks. Ask me again in a few days, and I'll have a totally different way to derail myself, and a conclusion to crash land into. I promise you this.

More on moral dilemmas of other natures some other time. Also, I just found out Aveeno and Axe test on animals. Axe feels particularly evil. No earthly creature should be subjected to the smell or feeling of Axe body spray. Jesus Christ.

[oetscop]

about to do some vladimir demikhov shit to dizzy and max

[drharshvardhanpuri2]

Lung Transplant Surgeon in Gurgaon and Delhi

Lung Transplant In Delhi and Gurgaon, India

A lung transplant is a surgical procedure to replace a diseased or failing lung with a healthy lung, usually from a deceased donor. A lung transplant is reserved for people who have tried medications or other treatments, but their conditions haven't sufficiently improved.

Depending on the medical condition, a lung transplant may involve replacing one of your lungs or both of them. In some situations, the lungs may be transplanted along with a donor heart.

While a lung transplant is a major operation that can involve many complications, it can greatly improve your health and quality of life.

History

Attempts at lung transplantation have occurred as early as 1946 when Vladimir Demikhov, a Soviet scientist, attempted single-lung transplantation in a dog. This transplant ultimately failed from bronchial anastomotic dehiscence, and difficulties with this anastomosis would plague clinical lung transplantation for the next 40 years. Henri Metras, in 1950, reported the first successful dog lung transplant and the first bronchial artery and left atrial anastomoses. In a nonhuman primate model, performed lung reimplantation and showed that these lungs were able to maintain function postoperatively, despite denervation. On June 11, 1963, reported the first human lung transplant; however, the patient died from kidney failure after 18 d. The first real survivor during this early era of lung transplantation was a patient of Fritz Derom’s in Belgium.This patient, however, survived only 10 mo. The failure of this early experience in clinical lung transplantation can be summarized by inadequate immunosuppression and difficulties with the bronchial anastomosis.

The advent of cyclosporine brought about significant improvements in patient survival following liver and kidney transplantation. This led to a resurgence of interest in heart/lung transplantation in Stanford and lung transplantation in Toronto. The first successful combined heart–lung transplant was completed by Reitz and colleagues and showed that a grafted lung could survive and function in a recipient. Research performed by Cooper’s group in Toronto showed that corticosteroid use appeared to be a significant factor in the weakness of the bronchial anastomosis. With the use of cyclosporine, corticosteroid use could be reduced, leading to improved bronchial healing. In 1986, the Toronto Lung Transplant Program reported the first successful single-lung transplantations for two patients with pulmonary fibrosis. This team went on to perform the first successful double-lung transplant, first with an en bloc technique that used a tracheal anastomosis, then evolving to the bilateral sequential transplantation technique that not only improved airway healing, but also had the additional benefit of avoiding cardiopulmonary bypass, if desired. This technique remains the standard technique in use to this day.

Indication

Lung transplantation is indicated for patients with chronic, end-stage lung disease who are failing maximal medical therapy, or for whom no effective medical therapy exists. General indications include:

·         Untreatable end-stage pulmonary disease of any etiology

·         Substantial limitation of daily activities

·         Limited life expectancy

·         Ambulatory patient with rehabilitation potential

·         Acceptable nutritional status

·         Satisfactory psychosocial profile and emotional support system

Some of the diseases that may require a lung transplant among this population include:

·         Chronic obstructive pulmonary disease (COPD)

·         Cystic fibrosis and bronchiectasis for other causes

·         Idiopathic pulmonary fibrosis and non-specific interstitial pneumonia

·         Pulmonary hypertension

·         Sarcoidosis

·         Lymphangioleiomyomatosis

·         Bronchoalveolar carcinoma

·         Re-transplant bronchiolitis obliterans

·         Bronchopulmonary dysplasia or chronic lung disease

·         Heart disease or heart defects affecting the lungs

Types of transplant

There are 3 main types of lung transplant:

A single lung transplant – where a single damaged lung is removed from the recipient and replaced with a lung from the donor; this is often used to treat pulmonary fibrosis, but it's not suitable for people with cystic fibrosis because infection will spread from the remaining lung to the donated lung.

A double lung transplant – where both lungs are removed and replaced with 2 donated lungs; this is usually the main treatment option for people with cystic fibrosis or COPD.

A heart-lung transplant – where the heart and both lungs are removed and replaced with a donated heart and lungs; this is often recommended for people with severe pulmonary hypertension. The demand for lung transplants is far greater than the available supply of donated lungs. This means a transplant will only be carried out if it's thought there's a relatively good chance of it being successful.

What is the procedure for lung transplant?

Lung transplantation is a complex surgical procedure performed to replace a diseased or damaged lung with a healthy lung from a donor. Here is a general overview of the procedure:

Evaluation and Listing: The process begins with an extensive evaluation to determine if a patient is a suitable candidate for lung transplantation. The evaluation involves medical tests, imaging studies, and consultations with a transplant team, including pulmonologists, surgeons, psychologists, and social workers. If the patient meets the criteria, they are placed on a waiting list for a suitable donor organ.

Waiting for a Donor: While waiting for a suitable donor, the patient undergoes regular check-ups and medical monitoring. The waiting time can vary significantly, ranging from days to months or even longer, depending on the availability of donor lungs that match the patient's blood type, tissue compatibility, and size.

Organ Matching: When a potential donor organ becomes available, a thorough assessment is conducted to determine its suitability for transplantation. The donor lung is evaluated based on factors such as blood type compatibility, tissue compatibility, size matching, and overall organ function.

Preparing for Surgery: Once a suitable donor lung is identified, the patient is notified, and preparations for surgery begin. The patient is admitted to the hospital, and pre-operative tests and procedures are performed. These may include blood tests, imaging studies, lung function tests, and discussions about the surgical process.

Anesthesia and Incision: On the day of surgery, the patient is brought to the operating room, and general anesthesia is administered. The surgeon makes an incision in the chest to access the diseased lung.

Lung Removal: The surgeon carefully removes the diseased lung while preserving surrounding blood vessels and airways. In some cases, both lungs may need to be removed, depending on the patient's condition.

Donor Lung Implantation: The healthy donor lung is prepared for transplantation by connecting the blood vessels and airways. The surgeon carefully sutures the blood vessels and airways of the new lung to the patient's existing blood vessels and airways.

Chest Closure: After the new lung is securely in place, the surgeon closes the incision in the chest using sutures or staples. Chest tubes may be inserted to drain excess fluid and air from the surgical site. 

Recovery and Post-Transplant Care: The patient is transferred to the intensive care unit (ICU) or a specialized transplant unit for close monitoring. Recovery after lung transplantation can be challenging, and the patient may need to stay in the hospital for several weeks. They will receive immunosuppressive medications to prevent organ rejection and undergo extensive rehabilitation, including physical therapy and respiratory exercises.

Follow-up Care: After discharge, the patient continues to receive ongoing care and regular follow-up visits with the transplant team. Long-term management involves taking immunosuppressive medications, monitoring lung function, and adopting a healthy lifestyle to promote overall well-being.

It's important to note that this is a general overview, and the specific details of the procedure can vary depending on the patient's condition, the transplant center, and the surgical techniques employed by the medical team.

Lung Transplant Surgeons in Gurgaon

Are you looking for the best lung transplant surgery in India at an affordable cost? Meet Dr. Harsh Vardhan Puri, a Lung Transplant Surgeon in Gurgaon and Delhi, India, who provides Lung Transplant.

[robbialy]

From • @ben_ditto_resurrections 🔛 Cerberus ⚪️ two-headed dogs created by Soviet scientist Vladimir Demikhov in the 1950s including extracts of documentary footage showing his process ⚪️ these extreme experiments paved the way for the first successfully completed heart and lung transplants in animals, procedures which have now saved many lives ⚪️ #medicaleducation https://www.instagram.com/p/CjGaaEcDkaORNbMyrEvwbX0mT58x5Ho-7AQjzU0/?igshid=NGJjMDIxMWI=

[moonami]

-“одна голова хорошо а две лучше”-(One head it's good, but two are better.)

Vladimir Petrovich Demikhov (Russian: Владимир Петрович Демихов; July 31, 1916 – November 22, 1998)[1] was a Soviet scientist and organ transplantation pioneer, who performed several transplants in the 1940s and 1950s, including the transplantation of a heart into an animal and a heart–lung replacement in an animal. He is also well known for his dog head transplants,[2] which he conducted during the 1950s, resulting in two-headed dogs.

-Wikipedia

(I like to think that the real reason why Ivan hides his neck is because he has a scars from various experiments he was subjected to in his time as the Soviet Union.

They probably wanted to see if he really was immortal and after discovering that apparently he was, they would start trying things like head transplants on him without fearing he died.)

-You want to win a free chibi drawing? Check this out!-

[gallifreyandistress]

The science monsters. With one you liking the most? tell me about it. 

[666silentthrone666]

!OGRE-Vladimir Demikhov Cassette Now Available!

...443ft of dog killing madness...      

https://ogre666.bandcamp.com/releases     

[amalgamatednervous]

Trump’s been working in the Kremlin with a two-headed dog.

(via Roky Erickson - Two Headed Dog (Red Temple Prayer) - YouTube)

[hirako5hinji]

reading about sergei brukhonenko and vladimir demikhov today and we are just 😭😭😭😭

[aiiaiiiyo]

Soviet scientist Vladimir Demikhov pictured next to the 2-headed dog he created. After 23 attempts of grafting dog heads onto the bodies of other dogs, he managed to create one that survived for 4 days by connecting their circulatory systems and vertebrae, 1959 (491x708) Check this blog!

[malhare-archive]

if we're talking about our historical fans 👀 vladimir demikhov is one of my favorite ppl to talk about!! he was SO fucked up despite contributing so much to science. I wouldn't recommend looking at the. image section of any of his articles if youre empathetic towards animals cuz. holy shit he did some fucked up experiments with dogs. brodyaga and shavka my beloveds...

OH MY GOD YEAH, THIS GUY!!!

I was like "wait he sounds so familiar--" then I looked him up and was immediately like "OH IT'S THE TWO HEADED DOG GUY!!" I never looked into him much because while I can appreciate his contributions to science and morbid stuff typically doesn't bother me, I just cannot handle the dog stuff omg I have way too much empathy for dogs in particular. He seems fascinating though!!

[myhauntedsalem]

True Urban Horror Legends

The urban horror legend of the living severed head. Most Urban legends are not true, however there are a few urban legends that are. Here is a true urban horror legend!

The Living Severed Head Legend

The Urban Legend: Your head will remain aware even after its been severed from your shoulders (giving you enough time to see your dead body and look around at the world you will soon be leaving). Legend has it, that severed heads have been known to blink, react to stimulus and try to communicate.

The Truth Behind The Urban Legend: Death by decapitation was assumed to be instant and painless in early history. The guillotine was designed for this reason, however there is evidence that your brain will remain aware for several seconds to minutes after your head gets cut off.

The most well known example of this comes from Dr. Beaurieux, who conducted and experiment on a French murder named Languille. After his beheading, Languille’s eyes and mouth started moving for about 6 seconds, until his brain had seemed to pass. At this point Dr. Beaurieux shouted his name and Languille eyes popped wide open staring directly at the doctor!

In The Doctors Own Words: “Languille’s eyes very definitely fixed themselves on mine, the pupils focusing themselves”. Doctor Beaurieux continued his experiments on guillotine victims and reported similar results for up to 30 seconds. There is a multitude of beheading stories like this throughout history. It’s estimated 20,000 to 40,000 people were beheaded during the French Revolution.

Researchers are finding that neurons, the cells that make up the brain, are active even after their blood supply is suddenly cut off. And they may show activity for longer than a minute. In an arguably not-so-humane study, Dutch scientists measured the brain activity in mice after slicing off the mice’s heads. What they saw was a quick flash of brain activity…

Another Living Head Story

This is about a U.S. Army veteran who had been stationed in Korea, in June 1989. He and his friend were in the back seat of a taxi when the taxi collided with a truck; the veteran was pinned in the wreckage, but his friend had been decapitated. Here is his letter:

“My friend’s head came to rest face up, and (from my angle) upside-down. As I watched, his mouth opened and closed no less than two times. The facial expressions he displayed were first of shock or confusion, followed by terror or grief. I cannot exaggerate and say that he was looking all around, but he did display ocular movement in that his eyes moved from me, to his body, and back to me. He had direct eye contact with me when his eyes took on a hazy, absent expression… and he was dead.”

Successful Head Transplants

In 1963, a group of scientists from Case Western Reserve University School of Medicine in Cleveland, Ohio, led by Robert J. White, a neurosurgeon and a professor of neurological surgery who was inspired by the work of Vladimir Demikhov, performed a highly controversial operation to transplant the head of one monkey onto another’s body.

The procedure was a success, with the animal being able to smell, taste, hear, and see the world around it. The operation involved cauterizing arteries and veins carefully while the head was being severed to prevent hypovolemia. Because the nerves were left entirely intact, connecting the brain to a blood supply kept it chemically alive. The animal survived for some time after the operation, even at times attempting to bite some of the staff.

Other head transplants were also conducted recently in Japan in rats. Unlike the head transplants performed by Dr. White, however, these head transplants involved grafting one rat’s head onto the body of another rat that kept its head. Thus, the rat ended up with two heads. The scientists said that the key to successful head transplants was to use low temperatures.

A human head transplant would most likely require cooling of the brain to the point where all neural activity stops. This is to prevent neurons from dying while the brain is being transplanted.

Ethical considerations have thus far prevented any reported attempt by surgeons to transplant a human being’s head. However, just imagine how the world would benefit by saving great minds like Albert Einstein or other geniuses.

[curiosityistheleastofmyproblems]

The Two Headed Dog

In 1954 Soviet Doctor Vladimir Demikhov began a series of groundbreaking yet disturbing experiments to conjoin dogs. Demikhov was a pioneer in transplantology, having successfully transplanted several organs including hearts and lungs in mammals. However, Demikhov wanted to go even further and perform a transplantation of a secondary dog head on to a dog using vascular connections to the host dogs heart.

For the first surgery, a stray german shepherd named Brodyaga (Tramp) and a small dog named Shavka were chosen. The surgery began by sedating both dogs. Shavka’s lower body was amputated just below the ribcage and the spine was severed. Her heart and lungs were kept connected until the very last minute. An incision was made at the base of the larger dogs neck and then began the process of carefully joining the two dogs blood vessels together and attaching Shavka’s trachea to Brodyaga’s lungs. The final stages involved removing Shavka’s lungs and heart. Her oesophagus was not attached to Brodyagas stomach and instead left outside. Both dogs vertebrae were attached together via plastic strings.

The operation took a mere 3 and a half hours. Both dogs were able to see, hear, smell and swallow. Although Shavka was able to drink, the liquid just drained out on to the floor. Sadly, Shavka and Brodyagas survived just 4 days.

In total Demikhov performed 24 of these surgeries, with varying success. The lifespan of these dogs varied from 4 days to 29 days. His transplantations were widely criticised by the Soviet Union for being unethical but it wasn’t until 1959 that America and Europe became aware of these operations. Although these incredible surgeries pioneered transplantation techniques there was very little direct application to human surgery, thus the purpose of these surgeries can be questioned. The last attempt in 1968 involving a puppy and a dog’s body was stuffed and sent to Riga’s Museum of History of Medicine.