#up covid vaccination

[dillyt]

Great news for uninsured adults in the USA who want a COVID-19 booster! It now appears that ALL CVS locations are now active participants in the Bridge Access Program. The Bridge Access Program gives out free Covid-19 vaccinations to 18+ adults who otherwise can't afford one, so if you have a CVS near you, please go get one! For others who don't have a CVS near them, please go to vaccines.gov, click on "Find Covid-19 vaccines", fill out which vaccines you prefer (you can mix different vaccines if you have to so i reccomend just marking all of them for the age groups you need), and when the next page loads mark the "Bridge Access Program Participant" option to see only locations that are Bridge Access Program participants. Hopefully, other places that aren't CVS will start participating soon, so just check back every so often to see if there are any updates. The CDC Bridge Access Program website also has more details on what locations will be participating, but only CVS is appearing as an active participant on the vaccines.gov location finder at the moment.

[brightlotusmoon]

[nando161mando]

[truth4ourfreedom]

JAPANESE DR TELLS IT LIKE IT IS ABOUT COVID VACCINES!

The word is spreading! He talks about how Moderna is dumping vaccines because no one will take them and about Fauci. Please like and repost!

[covid-safer-hotties]

Also preserved in our archive (Daily updates!)

At a Glance ~Researchers found that current COVID-19 vaccines fail to generate mature and durable antibody-producing cells in the bone marrow. ~The findings could help explain why protection tends to decline over time. ~Better understanding of long-term immune responses could lead to improved vaccines that provide enduring protection.

Some vaccines offer long-lasting protection. For instance, the tetanus vaccine provides protection for at least 10 years. With other vaccines, protection may begin to decline within a few months. To provide enduring immunity, a vaccine must elicit production of long-lived plasma cells, a type of immune cell that matures over time in the bone marrow and can rapidly trigger production of disease-fighting antibodies.

The mRNA vaccines developed for the SARS-CoV-2 virus have proven effective at preventing severe COVID-19 and reducing hospitalizations. These vaccines trigger production of antibodies that home in on the virus’s spike protein. But protective antibodies can begin to fade as soon as three months later and lead to breakthrough infections. Researchers have been puzzled by this waning protection, since SARS-CoV-2-specific immune cells can often be found in the bone marrow.

To better understand why protection against SARS-CoV-2 dwindles months after vaccination, a research team led by Dr. F. Eun-Hyung Lee of Emory University took a closer look at immune cells in the bone marrow of 19 healthy adults. Participants ranged in age from 20 to 65. All had previously received between two and five doses of mRNA COVID-19 vaccines. Samples of their bone marrow were evaluated within 33 months after receiving their initial COVID-19 vaccine shot.

The participants had also received an influenza vaccine within a year of giving their bone marrow samples. And all had previously received tetanus shots and boosters. Their responses to these previous vaccines were used for comparison.

The researchers used a cell-sorting technique called flow cytometry to separate each participant’s bone marrow immune cells into different groupings. These included short-lived antibody-secreting cells and long-lived plasma cells that confer lasting protection. Results appeared in Nature Medicine on September 27, 2024.

The scientists found that they could readily detect long-lived plasma cells that target tetanus and influenza. In contrast, while shorter-lived antibody-secreting cells specific to SARS-CoV-2 were abundant, long-lived ones were mostly absent. Even among five participants who had recent SARS-CoV-2 infections and vaccinations, long-lived plasma cells against the virus were scarce in the bone marrow samples.

The findings hint that newly created antibody-secreting cells against SARS-CoV-2 are unable to become fully mature and long-lasting once they reach and settle into the bone marrow. In contrast, vaccines against tetanus and influenza prompt antibody-producing cells to mature within bone marrow and become long-lived plasma cells. Future studies will need to investigate how to generate long-lived plasma cells against SARS-CoV-2.

“The holy grail of vaccine researchers is the generation of long-lived plasma cells,” Lee says. “Our findings demonstrate that current SARS-CoV-2 mRNA vaccines do not provide such long-lasting protection within bone marrow. Further research is needed to determine if updated vaccines, new delivery schedules, or other factors might provide such protection.”

—by Vicki Contie

[impishtubist]

So I know that James and Sirius's friendship is fundamental to Sirius's character, but bear with me: a universe where James, Lily, Sirius, and Remus never met. Maybe Remus was homeschooled, maybe Sirius went to another school, whatever. James and Lily still die, and Harry gets shipped off to the Dursleys with no godfather.

Years later, when he starts Hogwarts, he likes all his teachers, but he REALLY likes his DADA professor, Professor Black. Professor Black met his husband Remus after the war and they live in a cute little cottage in Hogsmeade, where Remus tends to their menagerie of frankly terrifying magical plants and creatures, and Professor Black teaches.

And Sirius is drawn to this scrawny, too-thin kid who very obviously does not have a good home life. He starts being friendly with Harry, inviting him to his office for tea, helping him with his assignments, probing a bit into his home life, but not too much, because he doesn't want Harry to shut down. Harry stays at Hogwarts over the holiday breaks, so Sirius stays too. He's really suspicious of the Dursleys, and keeps badgering McGonagall to let him take Harry for a break - maybe Easter, or a week in the summer. Harry gets to know his professor and Mr. Lupin really well, and always looks forward to seeing them/staying with them. Eventually, Remus clandestinely manages to gather enough evidence that the Dursleys are mistreating Harry, and Sirius makes a move for custody.

Basically, I love Sirius and Harry finding each other in every universe, even if Sirius doesn't know James or Lily 🥺

[milkweedman]

It is interesting how much math comes into even the most basic of like. Making things. Making almost anything. And often not numbers necessarily but proportions and geometry. I think all the time about how castles were built with geometry at the heart of it. And I use the same kind of proportional math to make socks fit. And none of my pieces are ever knit with a prime number of stitches--because you use factors to make neat colorwork and ribbing and different stitches. Idk ! I remember constantly thinking 'how the hell is THIS gonna come in useful ?' But it always does. Math is at the heart of everything, and knowing how to apply it is a tool of critical importance to Thinking Up A Shape And Making It.

[ben-lyintous]

so after a week of feeling like shit and experiencing some of the worst headaches i've ever had i just figured out i have completely lost my sense of smell too. do yourself a favor and go get your covid shot and your flu shot for the season if you can

[tylershmyler26]

WE DON'T LIVE IN A POST COVID WORLD 🌎

[yukipri]

Surviving after getting my updated Covid booster yesterday (and flu shot!).

My first time getting Moderna (past shots all Pfizer), and I felt like crap this morning, but after a good long nap I'm already feeling much better! If it just fades like this, it'll probably be the lightest reaction I've ever had to a Covid vaccine.

I also signed up for the Mpox vaccine at CVS, but when I got there, for some reason they said it wasn't available. Heard this happened to a few other folks too. Wonder why it was available on their site?

Either way, still feeling a bit drowsy and achey, but with my boys keeping me company I'll be better in no time! Get vaccinated folks!

Cats tag: #YukiPriASLKittens

[lawofcollage]

This is another piece of art I made while processing my ongoing anger with how the US specifically, though also many other countries, have completely ignored managing the covid pandemic for the last several years.

This is your reminder: there was a new vaccine released in September of 2023. If you have not had a vaccine since then, you need one.

Threadless, Redbubble

[catwouthats]

“How can this many people simply vote for Trump in the first place?”

✨Gaslighting✨

And

✨Teaching themselves apathy because they have been pushed to the brink and are only focused on their own survival and think that this guy will give it because he

gaslight themmmm✨

[nando161mando]

Why is everyone sick?

[gideonisms]

Once again frustrated by how Difficult it is to do very basic tasks

[covid-safer-hotties]

FDA Approves and Authorizes Updated mRNA COVID-19 Vaccines to Better Protect Against Currently Circulating Variants - Published Aug 22, 2024

Today, the U.S. Food and Drug Administration approved and granted emergency use authorization (EUA) for updated mRNA COVID-19 vaccines (2024-2025 formula) to include a monovalent (single) component that corresponds to the Omicron variant KP.2 strain of SARS-CoV-2. The mRNA COVID-19 vaccines have been updated with this formula to more closely target currently circulating variants and provide better protection against serious consequences of COVID-19, including hospitalization and death. Today’s actions relate to updated mRNA COVID-19 vaccines manufactured by ModernaTX Inc. and Pfizer Inc.

In early June, the FDA advised manufacturers of licensed and authorized COVID-19 vaccines that the COVID-19 vaccines (2024-2025 formula) should be monovalent JN.1 vaccines. Based on the further evolution of SARS-CoV-2 and a rise in cases of COVID-19, the agency subsequently determined and advised manufacturers that the preferred JN.1-lineage for the COVID-19 vaccines (2024-2025 formula) is the KP.2 strain, if feasible.

“Vaccination continues to be the cornerstone of COVID-19 prevention,” said Peter Marks, M.D., Ph.D., director of the FDA’s Center for Biologics Evaluation and Research. “These updated vaccines meet the agency’s rigorous, scientific standards for safety, effectiveness, and manufacturing quality. Given waning immunity of the population from previous exposure to the virus and from prior vaccination, we strongly encourage those who are eligible to consider receiving an updated COVID-19 vaccine to provide better protection against currently circulating variants.”

The updated mRNA COVID-19 vaccines include Comirnaty and Spikevax, both of which are approved for individuals 12 years of age and older, and the Moderna COVID-19 Vaccine and Pfizer-BioNTech COVID-19 Vaccine, both of which are authorized for emergency use for individuals 6 months through 11 years of age.

What You Need to Know

=Unvaccinated individuals 6 months through 4 years of age are eligible to receive three doses of the updated, authorized Pfizer-BioNTech COVID-19 Vaccine or two doses of the updated, authorized Moderna COVID-19 Vaccine.

=Individuals 6 months through 4 years of age who have previously been vaccinated against COVID-19 are eligible to receive one or two doses of the updated, authorized Moderna or =Pfizer-BioNTech COVID-19 vaccines (timing and number of doses to administer depends on the previous COVID-19 vaccine received).

=Individuals 5 years through 11 years of age regardless of previous vaccination are eligible to receive a single dose of the updated, authorized Moderna or Pfizer-BioNTech COVID-19 vaccines; if previously vaccinated, the dose is administered at least 2 months after the last dose of any COVID-19 vaccine.

=Individuals 12 years of age and older are eligible to receive a single dose of the updated, approved Comirnaty or the updated, approved Spikevax; if previously vaccinated, the dose is administered at least 2 months since the last dose of any COVID-19 vaccine.

=Additional doses are authorized for certain immunocompromised individuals ages 6 months through 11 years of age as described in the Moderna COVID-19 Vaccine and Pfizer-BioNTech COVID-19 Vaccine fact sheets.

=Individuals who receive an updated mRNA COVID-19 vaccine may experience similar side effects as those reported by individuals who previously received mRNA COVID-19 vaccines and as described in the respective prescribing information or fact sheets. The updated vaccines are expected to provide protection against COVID-19 caused by the currently circulating variants. Barring the emergence of a markedly more infectious variant of SARS-CoV-2, the FDA anticipates that the composition of COVID-19 vaccines will need to be assessed annually, as occurs for seasonal influenza vaccines.

For today’s approvals and authorizations of the mRNA COVID-19 vaccines, the FDA assessed manufacturing and nonclinical data to support the change to include the 2024-2025 formula in the mRNA COVID-19 vaccines. The updated mRNA vaccines are manufactured using a similar process as previous formulas of these vaccines. The mRNA COVID-19 vaccines have been administered to hundreds of millions of people in the U.S., and the benefits of these vaccines continue to outweigh their risks.

On an ongoing basis, the FDA will review any additional COVID-19 vaccine applications submitted to the agency and take appropriate regulatory action.

The approval of Comirnaty (COVID-19 Vaccine, mRNA) (2024-2025 Formula) was granted to BioNTech Manufacturing GmbH. The EUA amendment for the Pfizer-BioNTech COVID-19 Vaccine (2024-2025 Formula) was issued to Pfizer Inc.

The approval of Spikevax (COVID-19 Vaccine, mRNA) (2024-2025 Formula) was granted to ModernaTX Inc. and the EUA amendment for the Moderna COVID-19 Vaccine (2024-2025 Formula) was issued to ModernaTX Inc.

[lionbearfox]

the rarepair life is so brutal when it's two dead characters who people virtually never talk about at any level of complexity deeper than "taking canon at face value"