#residual disease

[marsupials-of-mars]

Yall aren't ready for the fact I kinned Bill cipher even harder when I was high last night (This has happened before when high, and i otherwise have terrible roleplay skills and do not kin in any way).

A way in which I felt co-concious and like I was actually going insane. To the point he told my girlfriend "this bitch with the body's gonna come out of this thinking I'm fictional and they were just high, but I'm HERE. it's ME."

To the point of him explaining to my girlfriend that this is part of his punishment. That he can only posses high fandom-diseased people because they have an easier time "breaking the seal between what's fiction and what's real". And that means he will never be taken seriously. And that he's being put in the most cringe possible scenario as some sick psychological torture. And that he's so much more than the silly mascot he is in this reality but we can't SEE that CAN WE?!

These are all things he said. And guess what, it's cringe as hell and all fiction. So that prophecy was fulfilled, I suppose.

[joellesolo]

Okay, well, I guess my appointment went as well as it could? I'm going to start lithium and latuda tonight after dinner, and, we'll see how they go? Wish me luck?

Lithium is brand new to me. I actually was not aware it was a bipolar medication until last night when I stumbled across a reddit post doing some meds research frantically (and google calling it the "gold standard treatment for bipolar," the "best mood stabilizer for mania," the "first drug of choice" for mania," etc. was also surprising) because I was diagnosed with bipolar disorder nearly fifteen years ago and I have never had a psychiatrist say, hey, let's try lithium! I just assumed (wrongly) it was an antidepressant or something else, that wasn't meant for me... but, yeah. There we go?

And, latuda, I was actually on for several years, and for the last couple of days I was going NUTS (well, you know what I mean) trying to figure out why I had stopped taking it in the first place, because I remember being stable and happy (or, as happy as I get, anyway) for a LONG time; did my insurance stop covering it? Did I develop weird side effects? Was that when we got married and started trying for Peanut and you can't get pregnant on it? I couldn't remember and, it was super fucking frustrating.

Luckily for me, my psychiatrist takes good notes, so when I asked, he immediately pulled it up and goes, "let's see, latuda... oh, yeah! You developed oculogyric crises so we had to stop it," and it was like, OH DUH. Instant recall. But I was apparently on the highest dose when that started happening, so, we're just going to take it slow and low, and... I'm just crossing my fingers and realllly hoping it doesn't start again because those crises were really fucking miserable 😭

But you know what else is miserable? A WEEKS LONG MANIC EPISODE WHERE YOU FEEL LIKE YOU'LL NEVER CALM DOWN AGAIN 😫🥴😭

(Fuck, I just wanted to write a QUICK UPDATE and then fucking lie down and this has already taken SIXTEEN FUCKING MINUTES SO FAR because I keep getting distracted and opening new tabs 😭😭😭)

The worst part is that although the lithium is supposedly 'fast-acting,' it doesn't kick in for five. fucking. days.

So I get to continue feeling like this for another five. FUCKING. DAYS.

IT'S ALREADY BEEN THIRTEEN DAYS OF THIS SHIT. COME ONNNN 😣

Alright, I'm going to lie down. Attempt to, anyway... I know no resting will be happening, but hopefully I'll be horizontal while I'm on my phone??

Oh, and, if anyone has any meal ideas for me, I have to take the latuda with 350 calories every night (I forgot about that part til I googled it and I'm on several meds that suppress my appetite so it's going to be super tough), I would appreciate any input! Michael is the cook of the family, because of my chronic fatigue, and my diet is, well... I'm lactose intolerant, and on a no/low-residue diet because of the Crohn's (meaning not a lot of fiber allowed (no fruits or vegetables for me)), so, I usually just have either nothing for dinner, or a grilled tuna or turkey sandwich or some soup, or just pastaroni (which, yes, contains dairy, I know, I pay for it); idk, dinners are hard for us because the girls are such picky eaters.... we used to meal plan and make actual dinners and stuff but the last year we've been not doing well at all just in general so now it's just nutella or tuna sandwiches or dino buddies or pastaroni or ramen. (Yeah. I know. Please don't judge us, we are literally doing our best 😭)

Fuck. It's been another ten minutes just for the rest of that. OKAY I'M GOING TO GET OFF THE COMPUTER AND LIE DOWN, I SWEAR! (now watch me type up like, ten minutes worth of tags... ugghhhh 😫)

[geraskier]

horrendous stomachache this morning that lasted for hours and hours. skin on my stomach and lower back feels incredibly sensitive still. im assuming i must have accidentally ingested gluten but i have no clue *how*. usually the gluten pain starts pretty soon after i eat it so i can tell what it was. i ate a bunch of corn chips before i went to bed last night, but those have never bothered me like this before, and i didn't wake up from the pain until 7ish. i had some progresso soups yesterday but neither of them had gluten according to the ingredients lists. (aside from that i had fruit, yogurt, etc. im really careful about what i eat and i don't normally eat "new" food items, meaning i stick to safe brands and flavors of things.)

still don't feel quite right.

[surinderbhalla]

Organic vs. Conventional Foods: Health Debate Unveiled

In the grocery aisle, the choice between organic and conventionally grown foods often leaves shoppers wondering about the health implications. Organic foods are often touted as a healthier choice. but, the debate over their superiority compared to conventionally grown foods has been ongoing. Various studies have yielded mixed results. Here’s in “Organic vs. Conventional Foods: Health Debate…

[clover-the-awesomest]

What trauma does to a person

part 14

oh no! raphs brain :(   …anyway

⇇ | ⇽ | index | ⇾

[123567-9qaaq9]

MRD Testing Market Segments Analysis, Current Challenges & Business Opportunities | Bis Research

Minimal Residual Disease (MRD) testing is a sophisticated diagnostic technique used primarily in oncology to detect and quantify residual cancer cells that may remain in the body during or after treatment. 

The global MRD testing market is a rapidly growing segment in the healthcare industry, driven by the increasing demand for accurate and sensitive methods to monitor and manage cancer patients. 

The MRD testing market was valued at $1.67 billion in 2023 and is expected to reach $6.67 billion by 2033, growing at a CAGR of 14.81% between 2023 and 2033. 

MRD Testing Overview 

Minimal residual disease testing is a technique used to detect and quantify the small number of cancer cells that remain in a patient's body after treatment. It involves sensitive technologies such as polymerase chain reaction (PCR), next-generation sequencing (NGS), and flow cytometry to identify residual disease at a molecular level. 

MRD testing market is clinically important as it helps to monitor treatment response, predict relapse risk, guide personalized therapies, and serve as an endpoint in clinical trials. By identifying and addressing MRD, healthcare providers can strive for better treatment outcomes and improved patient survival rates.

MRD testing, however, utilizes advanced molecular and genetic technologies to detect and quantify these residual cancer cells with unparalleled sensitivity. 

Have a look at our sample page here !

Market Segmentation 

By Technology

By Target Detection 

By End Users 

By Region 

China dominated the Asia-Pacific MRD testing market in 2022 with a share of 36.08%. Although the market is expected to remain in a strong growth phase due to the massively growing number of cancer cases and the rising health-related awareness among people in Asia-Pacific, a significant barrier to the increasing adoption is an uneven economic balance among countries within the region.

Key Factors- The MRD testing market has experienced significant growth in recent years, driven by several key factors like advancements in technology, rising cancer burden, clinical evidence supporting MRD monitoring

Key Players In the Minimum Residual Market includes 

QIAGEN N.V., Thermo Fisher Scientific, Inc., Sysmex Corporation, Mission Bio,OPKO Health, Bio-Rad Laboratories, Inc., ICON plc, Hoffmann-La Roche, and many others 

Minimal Residual Disease Testing Market 

Minimal Residual Disease  testing is a crucial component of cancer management aimed at detecting and monitoring residual cancer cells in patients who have undergone treatment. The primary goal of MRD testing is to identify and quantify the small number of cancer cells that may remain in the body after treatment, even when the patient shows no signs of disease.

Minimal residual testing represents a paradigm shift in cancer care, moving towards a more personalized and proactive approach by enabling clinicians to monitor disease dynamics with greater precision, ultimately leading to improved patient outcomes and enhanced quality of life.

Applications for Minimal Residual Testing Market 

Treatment Response Monitoring

Relapse Prediction

Treatment Decision-making

Prognostic Assessment 

Clinical Trials and drug development 

Recent Developments in the MRD Testing Market

•Quest Diagnostics acquired Haystack Oncology, expanding its oncology portfolio with the inclusion of advanced liquid biopsy technology. This addition aimed to enhance personalized cancer care by offering highly sensitive diagnostic capabilities. Integrated DNA Technologies launched the Archer FUSIONPlex Core Solid Tumor Panel, a pioneering cancer research testing solution that has been enhanced and fine-tuned to include a broader range of single nucleotide variant (SNV) and indel coverage.

Visit our vertical page here! 

Key Questions Answered 

Q What is MRD Testing ? 

 Minimal residual disease (MRD) testing is a supplementary approach to detect extremely low levels of blood cancer cells and solid tumors following the treatment of conditions such as acute and chronic leukemia, lymphoma, or multiple myeloma. MRD specifically pertains to the minute population of cancer cells that persist in the body despite achieving complete remission (CR) through chemotherapy or stem cell transplantation.

Q What kinds of New Strategies are adopted by the existing market players to strengthen their positions in the Industry ? 

The global MRD testing market is currently witnessing several developments, primarily aimed at introducing new products and services. Major manufacturers of MRD testing products, along with the service providers, are actively undertaking significant business strategies to translate success in research and development into the commercial clinical setting.

Conclusion 

MRD testing market represents a dynamic and evolving landscape, characterized by innovation, collaboration, and a shared commitment to revolutionizing cancer management. With its profound impact on clinical decision-making and patient care, MRD testing stands as a beacon of hope in the fight against cancer, heralding a new era of precision oncology.

[pinkcadillaccas]

I feel like the younger generation of queers have failed to learn the most important lesson from the AIDS crisis which is that barely 30 years ago major world governments were willing to let us die en masse because of their homophobia and racism and not enough has changed since then to guarantee they wouldn't do it again given the chance

[industryupdate]

Minimal Residual Disease Testing Industry Will Grow Fastest in Asia-Pacific

In 2022, the minimal residual disease testing market was worth around USD 1,156.8 million, and it is projected to advance at a 15.1% CAGR from 2022 to 2030, hitting USD 3,570.1 million in 2030, according to P&S Intelligence. This development can be ascribed to the increasing occurrence of solid tumors and hematological malignancies. Furthermore, the rising healthcare spending, also the…

[thebibliosphere]

I got hit with a moderately severe migraine on Friday (not sure if it was caused by the acupuncture on Thursday, but the acupuncture sure changed the shape of the migraine) and instead of forcing myself to “bounce back” the following day I spent all day yesterday mostly resting in between non taxing chores, and y’know what? I feel much better.

Shocker, I know.

Usually, after losing a whole day to being in bed with pain, there is the temptation to “make up” for it the next day by doing all the things I couldn’t while the migraine was happening (part of this is residual adrenaline from being in pain for 20+ hours). In my mind, it was a “fuck you” to the disease that took away my productivity.

This year I’m trying to reframe it.

Because in doing so I’m not saying fuck you to the disease. I’m just fucking myself over. So instead I’m no longer fighting. I’m resting.

In 2025 I am abandoning the concept of ‘productivity’ and replacing it with progress. And that progress includes the wellness I create for myself by resting.

2024 took me out at the knees. It was awful and debilitating. I am not obligated to bounce back from that. I do not have anything to make up for. I owe myself rest and care and compassion.

And I’m going to do my best to finally internalize that.

[ihazyourkitty]

I really try to avoid fact checking people in public comment sections on the internet, but sadly this time I couldn't resist.

There was a reel on Facebook explaining the "sad" reason why cetaceans in human care often receive ice. It's because they're given "dead fish" you see, and these frozen thawed fish contain less moisture than the live fish they eat in the wild, so the ice helps prevent dehydration.

First of all, this is half true. The other half is that many cetaceans just love getting ice.

Supplemental hydration can also include gelatin and squid. The latter two are not unique to cetaceans btw. Squid and specially formulated gelatin based foods are also used in many fish diets in part to provide additional moisture. They also count as enrichment, depending on the context.

In any event, this creator thinks it's sad... that caretakers are providing their dolphins additional hydration? What, does he also think it's sad that they get vitamins? Reptile keepers regularly dust their animals' food with calcium to make sure they don't get metabolic bone disease. Is that also sad? These things are standard zoological practices, not signs of neglect. Wouldn't it be sadder if they didn't do that?

(Reason #423 why framing matters).

"But it's not natural!"

Neither is running on a treadmill, but that doesn't mean it's bad for you. Also, I'm pretty sure ICE is one of the most natural things you could use....

"Well why can't they just give them live fish!?"

Because the logistics of sustaining a live colony for such a purpose would be an expensive nightmare. Do you know how many pounds of fish these animals need to eat in a day? Using them as an occasional form of enrichment might be feasible, but on the regular? Just. No! Tell me you don't know how fish care works without telling me you don't know how fish care works!

It's cruel to the fish, for the same reason that it's cruel to feed snakes live food (assuming they aren't picky eaters). Fish are not just props, they are live animals that can experience stress and pain!

Freezing the fish helps keep it safe to eat.

"Why not just release them back into the wild?"

Because that would also be cruel since they wouldn't know how to survive. Next question.

"How do they get dehydrated when they live in water!?"

Oh man. Oh man oh man.

Cetaceans get most of their hydration from their diet. A quick google search indicted that they can drink some salt water, though I don't know how true that is, and to be clear, their kidneys are likely much more efficient at filtering out salt than ours (someone who knows more about this, please feel free to correct me). Regardless, most of their hydration comes from their food. Lack of food leads to dehydration, both in captivity and in the wild.

But there was one guy who said that dolphins in captivity can't drink the water because it's chlorinated. This is not true. The residual amounts of chlorine left after their water passes through filtration is no higher than what is in your tap water.

(Btw, this is another reason why live fish aren't typically used, because you don't house fish in systems that use chlorine, even in small amounts).

When I pointed this out to the guy, his response was that "most of their diet contains water from the exact same source."

To his credit, he did back down when I pointed out that this was wrong. But come my friends! As a fish person, let me explain to you why this is not correct!

Fish blood chemistry is not the same as the ambient water around them. They would not be able to maintain homeostasis otherwise. You see, their gills and kidneys help them osmoregulate.

Freshwater fish blood contains more salts than the surrounding freshwater, which means the via osmosis, water will enter the body, and unless they can compensate for this, the fish will swell up like a balloon, lose necessary salts, and basically drown. So what do they do? Their kidneys produce large amounts of dilute urine get rid of this extra water. Meanwhile, chloride cells in their gills take up ions from the water to transport into their blood.

Saltwater fish, however, have the opposite problem. Their blood has less salts than the surrounding water, so they need to get rid of extra salt. How? Well, they actually do drink the saltwater, and then their kidneys help filter out the extra salt. They basically produce very concentrated urine. But the kidneys cannot do this alone, so the chloride cells in their gills also help by basically working in reverse. They move extra ions out of the blood.

Elasmobranchs, crustaceans, mollusks and other marine mammals that may also make up some cetacean diets will have their own methods of osmoregulation.

All of this is to say, no, eating saltwater animals does not mean you're literally consuming ocean water, as these organisms have specific mechanisms for filtering out the excess salts.

This is, btw, why you can't just put a freshwater fish in saltwater or vice versa. They will die. Nor is this unique to fish, most organisms adapted for one environment don't thrive in the other.* Case in point: we cannot drink salt water, because our kidneys cannot handle that.

But some animals can! Take the salmon for instance. They hatch in freshwater environments, then move to saltwater, and then back when spawning season comes. How do they do this? Well, there are specific environmental/developmental triggers that cause their bodies to start osmoregulating in reverse. This does not happen instantaneously, however. They need time to adjust. They will migrate to brackish water, and allow their bodies a few days to adjust before continuing.

Some species of fish have higher tolerances for wider ranges of salinity/total dissolved solids (TDS) than others. Fluctuating these levels can actually trigger spawning in some species too! Discus, for instance, can be maintained in relatively harder freshwater than what they'd experience in the wild. But for breeding purposes, it's recommended to use softer water with lower a TDS. Given that discus can be more finicky, however, any of these adjustments should be made gradually.

On the other hand, there might be another species where a more sudden change is beneficial. Tropical fish native to floodplains that will experience sudden onsets of flooding from the rainy season, for instance, may need precisely that sudden rush of freshwater with lower pH and TDS to trigger spawning. Even if spawning isn't the end goal, simulating these seasonal fluctuations can be a very effective form of naturalistic enrichment!

....Oh dear, I went on a very nerdy tangent, because SCIENCE!!!! Enjoy.

*this can actually be taken advantage of in certain treatment contexts! Saltwater aquarists will sometimes do what is called a "freshwater dip", where the saltwater fish is very briefly immersed in freshwater to help rid them of harmful external parasites or bacteria. Usually, it's used when fish are first brought into quarantine. It's not 100% effective on its own, but it's one of the many tools in an aquarist's arsenal. Oh! This can also be used on sea turtles in some rescue situations! Again... SCIENCE!!! >:D

[inbabylontheywept]

Realizing in hindsight that the only reason I was so skeptical about your camp story is that being covered in a combination of crusty, sticky pink residue and rotten fish oil for days on end while sleeping on a wooden floor in the Arizona heat sounded like such unbearable sensory agony that I wanted to convince myself it was fake, because I didn't want to believe that anybody had genuinely been through that. I'd have walked out of that place with a rucksack of pink ooze and either find my way back to civilization or become crispy pink buzzard chow after day 2.

Like, legitimately, I think about my reaction to that post a lot. The imagery was so deeply unpleasant that I was desperately scrambling to convince myself it wasn't true like I'd just found out my spouse was a serial killer. There was no torture, no death, no hunger or disease, just a bunch of sweaty guys being covered in sticky fruit-flavored slime, subjected to unpleasant smells, and sleeping blanketless on the floor. And you can't even smell! You were spared a good third of it! Yet your experience still horrified me worse than any war story, medieval torture device or horror movie for reasons I cannot hope to fathom.

idk, I've had this ask stewing in my head for months, but I keep forgetting to actually write and send it. In my heart of hearts, I knew your story was perfectly plausible. I was just grasping at straws, praying for you to admit that no, nobody has ever showered in off-brand Gatorade and then not slept for 3 days while being expected to attend uni lectures. It's all untrue, a ruse, a trick, and such things could never happen outside of the cruelest depths of hell. Santa Claus is real, teachers live in the school, babies are delivered by storks, and the pink sauce incident never happened.

My mom pulls me into a warm hug after I scrape my knee. The plastic egg I found under the couch opens to reveal a piece of chocolate. A dollar magically appears under the pillow where I'd put my tooth. All is well. I am safe. The universe is kind, and whoever's running it loves me.

It's a sunny August day and I'm holding a popsicle on the swingset. I'm using my plastic dinosaurs to act out an improvised battle between good guys and bad guys as I sit on the carpeted floor. I'm playing Fossil Fighters on my dinged-up Nintendo DS in the plush brown armchair by the window.

I add the carrot nose to my snowman. Candy plops into my Halloween bag. The speaker on the classroom wall announces that school's out for summer, and we all bound out the door with wild glee, free at last.

Panting, wheezing, I drag my battered form back into the cobbled-together wreckage of my innocence, only one arm remaining with which to drag myself, blood and intestines trailing behind me as the storm rages overhead, washing my entrails downstream. I huddle underneath what remains of my once-pristine shelter from the cold and wet, pulling the shards back together as best I can as the wind howls angrily, hatefully. It's no use. It's broken. It's gone. It cannot be repaired. My innocence will never return to me. The rain seeps through the cracks and lands upon my face.

The rain is pink, I realize, and I cry.

First off: I haven’t actually been on the receiving end of this before and I have to say, it's an almost literally gripping experience. I felt this rat for the last three paragraphs.

Incredibly well done. Second: If you just didnt' want to believe, that's fine, I barely have room in me for medium fries - a grudge would just pour out the top, too much tea for my cup. But you don't have to like, gaslight yourself into thinking the story is totally normal and believable (I always stretch my stories out a little) or beat yourself up over it for months. I meant it when I said we're good, you and I. It still makes me happy to see a comment or a like or, rarely, a question like this from you.

If it's just something that pops into your mind every now and again, I dunno, don't sweat it. I'd hate to give you a complex. Did I mention that I loved that writing for this? Incredible experience.

[inkeyjay]

Content warning: Blood, Gore, body horror

Diseased Relicary

Weird autopsies

An mild ailment corroded the streets of Arca two decades ago. The fevers were believed to be contracted throught the ingestion of contaminated fish and water. The vercals, renown healers, rose to power to ensure it wouldnt erradicate the city, but it ended making it worse. Health potions administered by Saint Trina's order were only capable of stopping the synthoms for a few days, and then they returned and so on. Anger festered in the streets, as only a few were able to afford such care and any attempts to replicate or look for a cure outside the order were crushed just as the poison filled vials between the teeths of their perpretators.

Queen Consuelo Vercal herself got the infection, but she endured years, for the monarch had the saints beside her. As the queen stood proudly on Arca Altus tall towers, the city withered at her feet. And another disease took the city: rebellion.

Only when the queen stepped down and took off the crown, as a final act of martydom, the plague was expelled from the city's lungs. The Nerón family then swore to legislate towards peace so the city could recover, not just from the epidemy, but also from the deep wounds that divided it.

The disease is now known as the Saltpeter fevers, due to its origin in the salty waters of the estuary, and the white residue pilling around the mouths of the ill. Just a few medics and forensic were able to see where it came from.

[2346khith]

‏Hello, I am Raneen from Gaza with my three children, Mohammed Rami and Julia 🇵🇸🍉. We have fled from one place to another, living in constant fear amidst severe shortages of food and medicine, hoping only to survive this brutal war. Please help me save my children from hunger and diseases. My daughter Julia suffers from severe chest allergies and the smells and residues of smoke have made things worse. She needs treatment and to live in a clean environment. We are suffering a lot. You can support my campaign by donating whatever you can or by sharing my posts to reach others who can help us survive the war to safety and peace. You are helping lives. Every donation makes a difference in our very difficult lives.🍉🙏🏻

For those who see this please, visit their blog and reblog their blog’s posts so they  get more attention and if you have the money to spare please donate.

Also I apologize, but I do not have the ability to donate to you. Trust me if I had the ability I would but I don't and I can't. I have no bank account or credit card to transfer money to and no job to gain any money. Every time I ask my parents to help they shut me down so this is the only way to help you. Please forgive me.

[covid-safer-hotties]

Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategy - Published Sept 21, 2003

Yes, you are reading that date right

Never let them tell you "we didn't know the risk." They knew. They just ignored all epidemiological best practices. For corporate profit.

Abstract Background Severe acute respiratory syndrome (SARS) is a febrile respiratory illness. The disease has been etiologically linked to a novel coronavirus that has been named the SARS-associated coronavirus (SARS-CoV), whose genome was recently sequenced. Since it is a member of the Coronaviridae, its spike protein (S2) is believed to play a central role in viral entry by facilitating fusion between the viral and host cell membranes. The protein responsible for viral-induced membrane fusion of HIV-1 (gp41) differs in length, and has no sequence homology with S2. Results Sequence analysis reveals that the two viral proteins share the sequence motifs that construct their active conformation. These include (1) an N-terminal leucine/isoleucine zipper-like sequence, and (2) a C-terminal heptad repeat located upstream of (3) an aromatic residue-rich region juxtaposed to the (4) transmembrane segment. Conclusions This study points to a similar mode of action for the two viral proteins, suggesting that anti-viral strategy that targets the viral-induced membrane fusion step can be adopted from HIV-1 to SARS-CoV. Recently the FDA approved Enfuvirtide, a synthetic peptide corresponding to the C-terminal heptad repeat of HIV-1 gp41, as an anti-AIDS agent. Enfuvirtide and C34, another anti HIV-1 peptide, exert their inhibitory activity by binding to a leucine/isoleucine zipper-like sequence in gp41, thus inhibiting a conformational change of gp41 required for its activation. We suggest that peptides corresponding to the C-terminal heptad repeat of the S2 protein may serve as inhibitors for SARS-CoV entry.

[literaryvein-reblogs]

Some Epidemiology Vocabulary

for your next poem/story

Epidemiology—The study of the distribution and determinants of health and disease in populations and its application to the prevention and control of health problems and diseases.

Droplet nuclei - The residue of dried droplets that may remain suspended in the air for long periods, may be blown over great distances, and are easily inhaled into the lungs and exhaled.

Fomite - An inanimate object that can be used to transmit an infectious agent. This may be contaminated transfusion products or injections, towels or bedding, surgical instruments, or contaminated food, water, or air.

Infectivity - The ability of an infectious agent to cause infection, measured as the proportion of people who become infected after being exposed to the infectious agent.

Portal of entry - A pathway into the host that gives an agent access to tissue that will allow it to multiply or act.

Portal of exit - A pathway by which an agent can leave its host.

Reservoir - The habitat in which an infectious agent normally lives, grows, and multiplies; reservoirs include humans, animals, and the environment.

Seasonality - Change in physiological status or in disease occurrence that conforms to a regular seasonal pattern.

Spot Map - A map that indicates the location of each case of a rare disease or outbreak by a place that is potentially relevant to the health event being investigated, such as where each case lived or worked.

Virulence - The ability of an infectious agent to cause severe disease, measured as the proportion of people with the disease who become extremely ill or die.

Zoonosis - An infectious disease that is transmissible under normal conditions from animals to humans.

Sources: 1 2 3 ⚜ More: Word Lists ⚜ Virus & Vaccine ⚜ Plague Writing Resources PDFs