#pipos charlotte

[izasfaceups]

Today's faceup is on a Pipos R.PI Charlotte in grey akin, along with a manicure and tail blush. She was a fun commission to work on, as I've always wanted to work on a Pipos doll!

I have a before and after of her, the previous faceup was done by the owner, but they wanted a more experienced hand for her fresh faceup. I was happy to oblige!

Want to see more of my work or commission me? Then please check out my website at www[dot]IzasFaceUps[dot]com!

[osatobjd]

My sweet Eve and Charlie ;_;

[athenaroseannatse]

Haven’t been on Tumblr for kind of a long time. Here’s Fatty in her puffy suit = v =+++ I’m planning to collect bodysuits of different colours and materials for her XD I just love to see her staying chubby LOL

[0strolist]

Another old artwork. I experimented with unfamiliar style using my bjd doll as a reference. The doll is pipos Charlotte. Maybe I should use this style more.

[dollysauruswrecks]

Does she seem like the type to go outside?

[osatokun]

Eve and Charlie!  Sweaters by @oversee-tblr

[jadepixel]

Pipos Charlotte [ jadepixel ]

[colesmurf22]

(OC) Pippie The Piplup

Bio: Pippie Piplup Name: Pippie Gender: Female Sexuality: Straight Birthday: July 1st Species: Piplup Relationship/Boyfriend: None yet Family Members: Piplupea (Mother) Kippie (Father) Rosalie (Grandma) Kimmie (Grandma) Sherman (Grandpa) Pat (Grandpa) Piplupbella (Aunt) Pico (Uncle) Kiley (Sister) Kipper (Brother) Zavier (Brother) Piper (Sister) Minda (Sister) Philip (Brother) Litten (Brother) Lippo (Brother) Arrin (Brother) Pippy (Twin Sister) Karrie (Sister) Piera (Younger Sister) Pierre (Younger Brother) Kimm (Younger Sister) Kipp (Youngest Brother) Kiro (Youngest Adopted Brother) Pira (Youngest Adopted Sister) Nuna (Trainer) Picabo (Cousin) Pacifico (Cousin) Pipo (Cousin) Pippo (Cousin) Piao (Cousin) Pipere (Cousin) Kicia (Cousin) Paloma (Cousin) Pacific (Cousin) Pacifica (Cousin) Porter (Cousin) Pippin (Cousin) Pio (Cousin) Pavel (Cousin) Phyllis (Cousin) Pipfla (Youngest Cousin) Pia (Youngest Cousin) Pollux (Youngest Cousin) Personality: Cute, Lovable, Cuddler, Friendly, and Polite Friends: Alenna (Best Friend) Mimmi Alexa Piprella (2nd Best friend) Thea (3rd best friend) Sasha (My bestie's oc and 4th best friend) Charlotte (My bestie's oc and 5th best friend) Melonie (My bestie's oc and 6th best friend) Brenda (My bestie's oc) Akara (My bestie's oc and 7th best friend) Kiana (Our oc) Berri (Our oc and 8th best friend) Belanna (Our oc and 9th best friend) Katin (Our oc and 10th best friend) Twilla (Our oc) Dana (My bestie's oc and 11th best friend) Nola Sunset (my bestie's oc) Mizzy Larra (My bestie's oc and 12th best friend) Zarah (Our oc) Favorite Color: Blue And Yellow Favorite Holiday: 4th of July Favorite Season: Summer Fun Fact: Pippie is a very cute piplup, she love doing cute things. To make her even more cuter. She is very lovable, a bunch of people think she is a lovable piplup. She is so lovable, that a bunch of people likes taking pictures of her. Because how lovable she is. She love cuddling, she cuddles with her trainer Nuna a lot. When her trainer is feeling down or having a bad day. She kind enough to give Nuna a cuddle. When she cuddles Nuna. She feels so much better. That's why she love cuddling. She also sometimes cuddle her twin sister. Her parents thinks it's cute seeing their twin daughters cuddle. That's why she is very nice cuddler. She may be cuddler and lovable. But she is very kind, especially to her twin sister. Usually siblings fight all the time. But not her, especially with her twin sister. She is very kind to her. She also likes sharing her things with her twin sister. And she is so polite, it is part of her being lovable. She is so polite to people, that everyone wants to give her a cuddle. Because how polite she is. That's why she love people being polity. If they are very polite. She is kind enough to give them cuddles and being lovable. Pippie belong to me and my number one bestie yoshilover1000 on FA Piplup species: Nintendo/Game Freak/Pokemon

[comicsalternative]

Episode 261: Reviews of Generation Gone, Vol. 1, Assassinistas #1, and Love and Rockets IV #4

Time Codes:

00:00:33 - Introduction

00:03:04 - Baby, it's cold outside

00:05:38 - Generation Gone, Vol. 1

00:37:45 - Assassinistas #1

00:55:04 - Love and Rockets IV #4

01:20:02 - Wrap up

01:21:16 - Contact us

This week Gwen and Derek take a look at three recent and exciting titles. They begin with the first trade collection of Aleš Kot and André Lima Araújo's Generation Gone (Image Comics). This initial volume establishes the premise of the intriguing series. The story focuses on three hackers who attempt to get into government systems, are discovered, and "infected" with genetic codes that give them supernatural powers. Gwen points out that, in some ways, this narrative is reminiscent of Katsuhiro Otomo’s Akira, although as Derek mentions, Kot and Araújo's world isn't anything post-apocalyptic. This first volume introduces what promises to be an engaging series and whets readers' appetites for what may follow.

Next, the Two People with PhDs Talking about Comics turn to the first of two Hernandez-infused comics covered this week. The first is Gilbert Hernandez and Tini Howard's Assassinistas #1, part of IDW Publications' and Shelly Bond's Black Crown imprint. The debut issue introduces us to three former assassins, two of which -- at least as far as we know -- have left that life and are attempting to "go legitimate" and live a normal life. However, drama erupts when one of the team, Charlotte “Scarlet” La Costa, has her son kidnapped, bringing another team member, Octavia “Red October” Price, back into a life she thought she had left behind her. And what of the third member of this one-time trio, Rosalyn “Blood” Diamond?  Both of the cohosts enjoyed this title, although the paratextual material in the back of this issue, commentary from editor Shelly Bond, is a bit conspicuous and doesn't add much.

Finally, Derek and Gwen wrap up by discussing the latest issue of Love and Rockets IV (Fantagraphics). This fourth issue picks up with the various storylines that both Jaime and Gilbert Hernandez have established going back to the previous Love and Rockets annuals. For Jaime, this means continuing the Princess Animus and Isle narratives, as well as giving us glimpses into both Maggie's and Hopey's pasts growing up in Hoppers. And then there's Derek's favorite part of this issue, a two-page focus on Ray that follows up on the events in The Love Bunglers. Gilbert's contributions gives us a brief glimpse into Killer's career choices, but there is also a Pipo storyline where this foundational character tries to come to terms with a relationship she once had in Palomar. In fact, in extended flashbacks, we're taken back to "classic" Palomar and characters we haven't seen for quite a while. But as Derek points out, one of the most striking things about this issue is that we see little of Fritz...and no mention at all of any Fritz imitators. A rarity in recent Love and Rockets issues!

Check out this episode!

[jassydolls]

Shops that specialize in walolita for bjd?

Anyone know any bjd clothing shops/seamstresses that specialize in walolita? I'm looking for a seamstress to commission a few walolita style dresses for my Pipos Charlotte. She can fit most if not all yo-sized stuff, but she's slim and busty. I'd prefer to work with someone who would be able to make the dresses using her measurements.

I'm currently looking at FeerieDollAtelier on Etsy but wanted to see if there were other shops I could go to. If anyone could point me in the right direction, I would really appreciate it!

ETA:

I'm also toying with the idea of getting a torso mod done to my Pipos Charlotte. Does anyone know a customizer that specializes in extensive body mods? I also want her modded so that her tail magnet can be inserted and lay flush against her bum area...

[i-am-very-very-tired]

Page Header Username Password Remember me Login Focus and scope Editorial team Submit an article Receive notifications Support Contact Impact factor: 1.500 JOURNAL CONTENT Search Search Browse By Issue By Author By Title HMPG HEALTH & MEDICAL PUBLISHING GROUP SAMA SOUTH AFRICAN MEDICAL ASSOCIATION Events | Careers | CPD Open access policy ARTICLE TOOLS Abstract Print this article How to cite item Email this article (Login required) Email the author (Login required) Post a Comment (Login required) Translate article Powered by Google TranslateTranslate CURRENT ISSUE Aug, 2017 Vol. 107 No. 8 POPULAR ARTICLES » Incidence of chemotherapy-induced neutropenia in HIV-infected and uninfected patients with breast cancer receiving neoadjuvant chemotherapy » Characteristics and correlates of alcohol consumption among adult chronic care patients in North West Province, South Africa » Corneal donations in South Africa: A 15-year review » Wilderness medicine in southern Africa » Acute high-altitude illness KEYWORDS AIDS Africa Antibiotic resistance Book review Children Epidemiology Ethics Guidelines HIV HIV/AIDS Influenza Malaria Mental health National Health Insurance South Africa Stroke Trauma Tuberculosis children epidemiology pregnancy Home About Register Search Issues Author Reviewer CPD Journals Announcements Home > Vol 102, No 8 (2012) > Green Allergic rhinitis in South Africa: 2012 guidelines R J Green, M Hockman, R Friedman, E Vardas, P Cole, A Halkas, C Feldman, on behalf of the South African Allergic Rhinitis Working Group (SAARWG) Department of Paediatrics and Child Health, University of Pretoria R J Green, MB BCh, FC Paed (SA), MMed (Paed), PhD, FRCP Private Practice, Linksfield Clinic, Johannesburg M Hockman, BSc, MB BCh, FCS (SA) (ORL) Private Practice, Linksfield Clinic and Sandton Clinic, Johannesburg R Friedman, MB BCh, FCS (SA) (ORL) Lancet Laboratories and Division of Medical Virology, Faculty of Health Sciences, Tygerberg Campus, Stellenbosch University E Vardas, BSc (Hons), MB BCh, DTM&H, DPH, MMed Virology, FC Path Clinical Virology (SA) Lancet Laboratories, Johannesburg, South Africa P Cole, MB BCh, MMed (Chem Path) Private Practice, Netcare Krugersdorp Hospital A Halkas, MB BCh, FC Paed (SA), MMed (Paed) Charlotte Maxeke Johannesburg Academic Hospital and University of the Witwatersrand, Johannesburg C Feldman, MB BCh, DSc, PhD, FRCP, FCP (SA) Corresponding author: R J Green (robin.green@up.ac.za) Background. Allergic rhinitis (AR) is an important disease in South Africa. The South African Allergic Rhinitis Working Group (SAARWG) has published previous guidelines for AR diagnosis and management. Areas of concern have arisen that require additional information, including the management of AR in infancy, appropriate and inappropriate allergy testing, cost of AR management, diagnosis and distinguishing the condition from sinusitis, use of over-the-counter medications, and the concept of the ‘united airway’. Recommendations. Clinicians should consider the possibility of AR in infants with recurrent nasal symptoms. Allergy testing should be used wisely and based on local allergens. Total IgE testing is not routinely required to prove allergy. Acute and chronic sinusitis should be considered in conjunction with AR; treatment of rhinitis will improve these conditions. Over-the-counter medications should be used sparingly and with caution. Concern for long-term use of topical decongestants must be noted. Asthma should always be considered in AR diagnosis. Immunotherapy is available in SA and may be extremely useful in selected AR patients. Conclusion. The SAARWG proposed an algorithm for the diagnosis and management of rhinitis in South Africa. AR is common, important and troubling to patients; therefore, every effort should be made to target therapy correctly. Patient education is important in the management of AR. S Afr Med J 2012;102(8):693-696. DOI:10.7196/SAMJ.5810 1. Introduction This report concerns problematic issues in the diagnosis and management of allergic rhinitis (AR) in South Africa, as reviewed by the South African Allergic Rhinitis Working Group (SAARWG) in February 2012. 2. AR in infants Practical paediatric experience suggests that AR in infants, first reported in 1961,1 is not uncommon. However, its prevalence is unknown and complicated by inconclusive studies suggesting that ‘seasonal AR’ is uncommon in the first 2 years of life.2 The 2003 prospective study on the influence of perinatal factors on the occurrence of asthma and allergies (PIPO) in Belgium surveyed 1 300 infants from the general population.3 In the first phase of the study, 260 infants were monitored to the age of 1 year and subjected to a questionnaire, clinical examination and allergy testing. At the end of the first phase, 44% of the infants were reported to have snoring and noisy breathing, while positive allergy test results were reported in 21%. While this does not prove the existence of AR in infancy, it suggests that this diagnosis is probable in some infants. The following symptoms should be sought where AR is considered in infants: noisy breathing, snuffles, snorting; snoring; sneezing; feeding difficulty; failure to thrive; irritability, disturbed sleep; watery nasal discharge; nose-rubbing on pillow/bedding/mother; recurrent serous otitis media; and cough/wheeze. Features on examination that suggest AR in infants include: facial appearance (allergic facies); pallor; Dennie-Morgan lines; mouth-breathing; tongue thrusting; a pale, wet and swollen nasal mucosa; serous otitis media; and atopic dermatitis (often present). Skin-prick tests are useful for identifying allergens, even in very young children, and they require only a limited panel. The most common allergens originate from foods (especially milk, peanut and wheat) and inhalants (especially house dust mite, cats and dogs). There is no published literature on the manner in which to treat AR in infants. However, 3 aspects of treatment deserve mention: (i) The avoidance of identified allergens and irritants (especially passive environmental tobacco smoke) is critical. Parents must also be advised to avoid unnecessary and potentially harmful therapies, including most over-the-counter (OTC) cough and cold medications and topical decongestants. (ii) The use of saline nasal preparations should strongly be recommended. (iii) All forms of therapy for older children (including antihistamines, topical corticosteroids and montelukast) are not registered for use in infants. While their use is often necessary, clinicians must be careful to balance efficacy with safety. 3. Laboratory-based allergy surveillance in private practice (2007 - 2011) Allergy data from South Africa and Africa are limited, with infrequent updates on circulating aero-allergens and the possible impact of climate change. Existing studies are not generalisable, have small sample sizes and assess specific populations. Therefore, alternative ways to audit allergy data have been suggested, including laboratory surveillance of allergy test requests and identified allergens.4 To assess the usefulness of laboratory-based allergy surveillance, all allergy test requests and results from 1 September 2007 to 31 August 2011 were extracted from Lancet Laboratories (South Africa and Africa). Test results including total immunoglobulin E (IgE), ImmunoCAP, Immuno solid-phase allergen chip (ISAC), eosinophil cationic protein (ECP) and skin-prick tests were analysed, and data on trends (seasonal), location (country, province and district), doctor type and patient profile (age and sex) were collected. In total, 1 150 493 allergy-related tests were requested (Table 1), including 129 848 requests for total IgE. Although clinical information was not available, it is assumed that total IgE requests were used primarily as part of an allergy work-up. Most published allergy testing guidelines from South Africa and the rest of the world discourage the use of total IgE as a screening test for allergy.5 , 6 The SAARWG stresses the importance of an adequate history in uncovering likely allergens as a source of AR. The 2011 total paediatric allergy testing expenditure of the large healthcare funder, Discovery Health, approximated R10 million. ImmunoCAP testing contributed to 66% of the expenditure, while 11.2% was spent on total IgE testing in children aged ≤16 years (Discovery Health, 2010). Directed testing according to established algorithms with appropriate screening and follow-up tests must be emphasised in practice. 4. Diagnosis of AR and sinusitis AR is an inflammatory condition of the lining of the nose, characterised by nasal symptoms, including anterior or posterior rhinorrhoea, sneezing, nasal blockage and/or itching of the nose, often associated with ocular symptoms.7 Itch, sneeze and profuse rhinorrhoea are classic of early AR. However, nasal obstruction manifests as a prominent symptom with time.8 Ocular symptoms present with itchy, red and watery eyes.9 The diagnosis of sinusitis is guided by a recent European position paper on rhinosinusitis and nasal polyps (EPOS).10 The document makes the case that acute rhinosinusitis is often viral and related to an upper respiratory tract infection (URTI) (Table 2). Acute bacterial sinusitis may be considered when symptoms persist for longer than 10 days. The diagnosis of chronic sinusitis is warranted by symptoms persisting for longer than 12 weeks. 5. AR and sinusitis treatment principles Intranasal corticosteroids (INS) are the gold-standard first-line therapy for moderate/severe and/or persistent AR.10 Several studies found INS to be more effective than anti-histamines (AH) against nasal symptoms.7 , 11 , 12 INS treatment may optimise the control of co-morbidities such as asthma, sinusitis, conjunctivitis and otitis media.13 , 14 Acute bacterial sinusitis (ABS) is most often preceded by a viral URTI. Other factors that may lead to inflammation of the nose and paranasal sinuses and predispose to ABS include allergy, trauma and dental infection. Outcomes deemed necessary for managing ABS include eradication of bacterial pathogens from the site of infection, returning the sinuses to health, decreasing the duration of symptoms, preventing severe complications and decreasing the likelihood of chronic disease. There is mounting evidence that topical INS treatment is beneficial in managing ABS.15 , 16 6. Evidence for the value of OTC cough and cold medicines OTC cough and cold medicines are frequently used by patients and often prescribed by doctors. Evidence is absent or negative for efficacy for many of these preparations. Cough mixtures have no proven value in adults or children in upper (URT) and lower respiratory tract (LRT) pathologies.17 Mucolytic agents have been studied and a meta-analysis of 3 studies reveals that they have some benefit in URTIs.18 Oral decongestants and antihistamines have not demonstrated efficacy in most clinical conditions.19 , 20 The lack of efficacy and unfavourable safety profile of many agents is a major concern. The use of most agents in young children has recently been restricted in the USA.21 However, even legal restriction has not shown changed prescription or usage patterns in many countries.22 Topical decongestants improve the major symptoms of nasal congestion in AR. However, their use may produce rhinitis medicamentosa, which may occur as early as day 3 in some patients. Their use should therefore be restricted to no more than 7 - 10 days.23 7. The ‘united airway’ concept – renewed interest Despite discussion by world experts on the link between AR and asthma, the SAARWG believes that the evidence strongly supports the concept of a ‘united airway’ and that the identification and management of both conditions (AR and asthma) improves symptoms and quality of life, reduces severity of disease and is cost-saving.24 The reasoning for a link between AR and asthma centres on the systemic nature of inflammation in these conditions operating on a common epithelium in both sites.29 8. Immunotherapy Patients with persistent AR, affecting quality of life and resistant to maximal therapy, should be assessed for sensitisation. Patients who are monosensitive or ‘clinically monosensitive’ (i.e. sensitised to more than one allergen but with a clear pattern demonstrating one allergen as the important one) should be offered immunotherapy.30 9. Algorithm for the diagnosis and management of rhinitis An algorithm proposed by the SAARWG for the diagnosis and management of rhinitis in South Africa is presented Fig. 1. 10. Conclusion AR is common, important and troubling to patients; therefore, every effort should be made to target therapy correctly. Patient education is important in the management of AR. SAARWG members: G Carter, G Des Marais, C Els, C Gravett, I Hunt, M Ossip, O F Jooma, A Manjra, L Maron, A Mc Cullogh, M McDonald, P C Potter, R Seedat, and L Woolf. Endorsements. This Guideline is endorsed by the Allergy Society of South Africa. Acknowledgements. The SAARWG acknowledges an unrestricted grant from Aspen/GSK Pharmaceuticals for sponsorship of the working group meeting on 10 - 12 February 2012, where these guidelines were reviewed. References 1. Hill LW. Certain aspects of allergy in children. A critical review of the recent literature. N Engl J Med 1961;265:1298-1304. [http://dx.doi.org/ 10.1056/NEJM196112282652607] 1. Hill LW. Certain aspects of allergy in children. A critical review of the recent literature. N Engl J Med 1961;265:1298-1304. [http://dx.doi.org/ 10.1056/NEJM196112282652607] 2. Nickel R, Lau S, Niggemann B, et al. Messages from the German Multicentre Allergy study. Pediatr Allergy Immunol 2002;13 Suppl 15:7-10. [http://dx.doi.org/10.1034/j.1399-3038.13.s.15.4.x] 2. Nickel R, Lau S, Niggemann B, et al. Messages from the German Multicentre Allergy study. Pediatr Allergy Immunol 2002;13 Suppl 15:7-10. [http://dx.doi.org/10.1034/j.1399-3038.13.s.15.4.x] 3. Van Bever HP, Desager KN, Hagendorens M. Critical evaluation of prognostic factors in childhood asthma. Pediatr Allergy Immunol 2002;12:1-9. [http://dx.doi.org/ 10.1034/j.1399-3038.2002.00093.x] 3. Van Bever HP, Desager KN, Hagendorens M. Critical evaluation of prognostic factors in childhood asthma. Pediatr Allergy Immunol 2002;12:1-9. [http://dx.doi.org/ 10.1034/j.1399-3038.2002.00093.x] 4. Berman D, Climate change and aeroallergens in South Africa. Curr Allergy Clin Immunol 2011;24:65-71. 4. Berman D, Climate change and aeroallergens in South Africa. Curr Allergy Clin Immunol 2011;24:65-71. 5. Motala C, Hawarden D. Diagnostic testing in allergy. S Afr Med J 2009;99:531-535. [http://dx.doi.org/S0256-95742009000700019] 5. Motala C, Hawarden D. Diagnostic testing in allergy. S Afr Med J 2009;99:531-535. [http://dx.doi.org/S0256-95742009000700019] 6. Eigenmann PA, Oh JW, Beyer K. Diagnostic testing in the evaluation of food allergy. Pediatr Clin North Am 2011;58(2):351-62. [http://dx.doi.org/10.1016/j.pcl.2011.02.003] 6. Eigenmann PA, Oh JW, Beyer K. Diagnostic testing in the evaluation of food allergy. Pediatr Clin North Am 2011;58(2):351-62. [http://dx.doi.org/10.1016/j.pcl.2011.02.003] 7. Bousquet J, Van Cauwenberge P, Khaltaev N; Aria Workshop Group; World Health Organization. Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol 2001;108:S147–S334. 7. Bousquet J, Van Cauwenberge P, Khaltaev N; Aria Workshop Group; World Health Organization. Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol 2001;108:S147–S334. 8. Luyt DK, Green RJ, Davis G, et al. Consensus document: allergic rhinitis in South Africa - diagnosis and management. S Afr Med J 1996;56(10):1315-1328. 8. Luyt DK, Green RJ, Davis G, et al. Consensus document: allergic rhinitis in South Africa - diagnosis and management. S Afr Med J 1996;56(10):1315-1328. 9. Phipatanakul W. Allergic rhinoconjunctivitis: epidemiology. Immunol Allergy Clin North Am 2005;25(2):263-281. 9. Phipatanakul W. Allergic rhinoconjunctivitis: epidemiology. Immunol Allergy Clin North Am 2005;25(2):263-281. 10. Thomas M, Yawn BP, Price D, Lund V, Mullol J, Fokkens W; European Position Paper on Rhinosinusitis and Nasal Polyps Group. EPOS Primary Care Guidelines: European Position Paper on the Primary Care Diagnosis and Management of Rhinosinusitis and Nasal Polyps 2007 - a summary. Prim Care Respir J 2008;17(2):79-89. [http://dx.doi.org/10.3132/pcrj.2008.00029] 10. Thomas M, Yawn BP, Price D, Lund V, Mullol J, Fokkens W; European Position Paper on Rhinosinusitis and Nasal Polyps Group. EPOS Primary Care Guidelines: European Position Paper on the Primary Care Diagnosis and Management of Rhinosinusitis and Nasal Polyps 2007 - a summary. Prim Care Respir J 2008;17(2):79-89. [http://dx.doi.org/10.3132/pcrj.2008.00029] 11. New England Medical Center Evidence-based Practice Center. Management of Allergic and Nonallergic Rhinitis. Evidence Report/Technology Assessment Number 54, 2002. 11. New England Medical Center Evidence-based Practice Center. Management of Allergic and Nonallergic Rhinitis. Evidence Report/Technology Assessment Number 54, 2002. 12. Ratner PH, van Bavel JH, Martin BG, et al. A comparison of the efficacy of fluticasone propionate aqueous nasal spray and loratadine, alone and in combination, for the treatment of seasonal allergic rhinitis. J Fam Pract 1998;47(2):118-125. 12. Ratner PH, van Bavel JH, Martin BG, et al. A comparison of the efficacy of fluticasone propionate aqueous nasal spray and loratadine, alone and in combination, for the treatment of seasonal allergic rhinitis. J Fam Pract 1998;47(2):118-125. 13. Settipane RA. Complications of allergic rhinitis. Allergy Asthma Proc 1999;20:209-213. [http://dx.doi.org/10.2500/108854199778339053] 13. Settipane RA. Complications of allergic rhinitis. Allergy Asthma Proc 1999;20:209-213. [http://dx.doi.org/10.2500/108854199778339053] 14. Crystal-Peters J, Neslusan C, Crown WH, Torres A. Treating allergic rhinitis in patients with comorbid asthma: the risk of asthma-related hospitalizations and emergency department visits. J Allergy Clin Immunol 2002;109:57-62. 14. Crystal-Peters J, Neslusan C, Crown WH, Torres A. Treating allergic rhinitis in patients with comorbid asthma: the risk of asthma-related hospitalizations and emergency department visits. J Allergy Clin Immunol 2002;109:57-62. 15. Meltzer EO, Teper A, Danzig M. Intranasal corticosteroids in the treatment of acute rhinosinusitis. Curr Allergy Asthma Rep 2008;8(2):133-138. [http://dx.doi.org/10.1007/s11882-008-0023-9] 15. Meltzer EO, Teper A, Danzig M. Intranasal corticosteroids in the treatment of acute rhinosinusitis. Curr Allergy Asthma Rep 2008;8(2):133-138. [http://dx.doi.org/10.1007/s11882-008-0023-9] 16. Meltzer EO, Bachert C, Staudinger H. Treating acute rhinosinusitis: comparing efficacy and safety of mometasone furoate nasal spray, amoxicillin, and placebo. J Allergy Clin Immunol 2005;116(6):1289-1295. [http://dx.doi.org/10.1016/j.jaci.2005.08.044] 16. Meltzer EO, Bachert C, Staudinger H. Treating acute rhinosinusitis: comparing efficacy and safety of mometasone furoate nasal spray, amoxicillin, and placebo. J Allergy Clin Immunol 2005;116(6):1289-1295. [http://dx.doi.org/10.1016/j.jaci.2005.08.044] 17. Dicpinigatis PV. Currently available antitussives. Pulm Pharm Ther 2009;22:148-151. [http://dx.doi.org/10.1016/j.pupt.2008.08.002] 17. Dicpinigatis PV. Currently available antitussives. Pulm Pharm Ther 2009;22:148-151. [http://dx.doi.org/10.1016/j.pupt.2008.08.002] 18. Chang CC, Cheng AC, Chang AB. Over-the-counter (OTC) medications to reduce cough as an adjunct to antibiotics for acute pneumonia in children and adults. Cochrane Collaboration 2010;10. [http://dx.doi.org/10.1002/14651858.CD006088.pub2] 18. Chang CC, Cheng AC, Chang AB. Over-the-counter (OTC) medications to reduce cough as an adjunct to antibiotics for acute pneumonia in children and adults. Cochrane Collaboration 2010;10. [http://dx.doi.org/10.1002/14651858.CD006088.pub2] 19. Eyibilen A, Aladağ I, Güven M, Koç S, Gürbüzler L. The effectiveness of nasal decongestants, oral decongestants and oral decongestant-antihistamines in the treatment of acute otitis media in children. Kulak Burun Bogaz Ihtis Derg 2009;19(6):289-293. 19. Eyibilen A, Aladağ I, Güven M, Koç S, Gürbüzler L. The effectiveness of nasal decongestants, oral decongestants and oral decongestant-antihistamines in the treatment of acute otitis media in children. Kulak Burun Bogaz Ihtis Derg 2009;19(6):289-293. 20. Shaikh N, Wald ER, Pi M. Decongestants, antihistamines and nasal irrigation for acute sinusitis in children. Cochrane Database of Systematic Reviews 2010;12. [http://dx.doi.org/10.1002/14651858.CD007909.pub2] 20. Shaikh N, Wald ER, Pi M. Decongestants, antihistamines and nasal irrigation for acute sinusitis in children. Cochrane Database of Systematic Reviews 2010;12. [http://dx.doi.org/10.1002/14651858.CD007909.pub2] 21. Centers for Disease Control and Prevention (CDC). Revised product labels for pediatric over-the-counter cough and cold medicines. MMWR Morb Mort Wkly Rep 2008;57:1180. 21. Centers for Disease Control and Prevention (CDC). Revised product labels for pediatric over-the-counter cough and cold medicines. MMWR Morb Mort Wkly Rep 2008;57:1180. 22. Sen EF, Verhamme KM, Felisi M, ‘t Jong GW, Giaquinto C, Picelli G, Ceci A, Sturkenboom MC; TEDDY European Network of Excellence. Effects of safety warnings on prescription rates of cough and cold medicines in children below 2 years of age. Br J Clin Pharmacol 2011;71(6):943-950. [http://dx.doi.org/10.1111/j.1365-2125.2010.03860.x] 22. Sen EF, Verhamme KM, Felisi M, ‘t Jong GW, Giaquinto C, Picelli G, Ceci A, Sturkenboom MC; TEDDY European Network of Excellence. Effects of safety warnings on prescription rates of cough and cold medicines in children below 2 years of age. Br J Clin Pharmacol 2011;71(6):943-950. [http://dx.doi.org/10.1111/j.1365-2125.2010.03860.x] 23. Tran NP, Vickery J, Blaiss MS. Management of rhinitis: allergic and non-allergic. Allergy Asthma Immunol Res 2011;3(3):148–156. [http://dx.doi.org/10.4168/aair.2011.3.3.148] 23. Tran NP, Vickery J, Blaiss MS. Management of rhinitis: allergic and non-allergic. Allergy Asthma Immunol Res 2011;3(3):148–156. [http://dx.doi.org/10.4168/aair.2011.3.3.148] 24. Huse DM, Harte SC, Russel MW, et al. Allergic rhinitis may worsen asthma symptoms in children: the International Asthma Outcomes Registry. Am J Respir Crit Care Med 1996;153:A860. 24. Huse DM, Harte SC, Russel MW, et al. Allergic rhinitis may worsen asthma symptoms in children: the International Asthma Outcomes Registry. Am J Respir Crit Care Med 1996;153:A860. 25. Leynaert B, Neukirch C, Liard R, et al. Quality of life in allergic rhinitis and asthma: A population-based study of young adults. Am J Respir Crit Care Med 2000;162:1391-1396. 25. Leynaert B, Neukirch C, Liard R, et al. Quality of life in allergic rhinitis and asthma: A population-based study of young adults. Am J Respir Crit Care Med 2000;162:1391-1396. 26. Welsh PW, Stricker WE, Chu C-P, et al. Efficacy of beclomethasone nasal solution, flunisolide and cromolyn in relieving symptoms of ragweed allergy. Mayo Clin Proc 1987;62:125-134. 26. Welsh PW, Stricker WE, Chu C-P, et al. Efficacy of beclomethasone nasal solution, flunisolide and cromolyn in relieving symptoms of ragweed allergy. Mayo Clin Proc 1987;62:125-134. 27. Yawn BP, Yuringer JW, Wollan PC, et al. Allergic rhinitis in Rochester, Minnesota residents with asthma: frequency and impact on health charges. J Allergy Clin Immunol 1999;103:54-59. 27. Yawn BP, Yuringer JW, Wollan PC, et al. Allergic rhinitis in Rochester, Minnesota residents with asthma: frequency and impact on health charges. J Allergy Clin Immunol 1999;103:54-59. 28. Crystal-Peters J, Neslusan C, Crown WH, et al. Treatment of allergic rhinitis in patients with comorbid asthma: the risk of asthma related hospitalizations and emergency department visits. J Allergy Clin Immunol 2002;109:57-62. [http://dx.doi.org/10.1067/mai.2002.120554] 28. Crystal-Peters J, Neslusan C, Crown WH, et al. Treatment of allergic rhinitis in patients with comorbid asthma: the risk of asthma related hospitalizations and emergency department visits. J Allergy Clin Immunol 2002;109:57-62. [http://dx.doi.org/10.1067/mai.2002.120554] 29. Corren J. Allergic rhinitis and asthma: How important is the link? J Allergy Clin Immunol 1997;99:S781-S786. [http://dx.doi.org/10.1016/S0091-6749(97)70127-1] 29. Corren J. Allergic rhinitis and asthma: How important is the link? J Allergy Clin Immunol 1997;99:S781-S786. [http://dx.doi.org/10.1016/S0091-6749(97)70127-1] 30. Radulovic S, Wilson D, Calderon M, Durham S. Systematic reviews of sublingual immunotherapy (SLIT). Allergy 2011;66(6):740-752. [http://dx.doi.org/10.1111/j.1398-9995.2011.02583.x] 30. Radulovic S, Wilson D, Calderon M, Durham S. Systematic reviews of sublingual immunotherapy (SLIT). Allergy 2011;66(6):740-752. [http://dx.doi.org/10.1111/j.1398-9995.2011.02583.x] Accepted 11 April 2012. Table 1. Allergy-related tests conducted by Lancet Laboratories, South Africa and Africa (2007 - 2011) Test Number of tests performed ( n ) 1 September 2007 - 31 August 2008 1 September 2008 - 31 August 2009 1 September 2009 - 31 August 2010 1 September 2010 - 31 August 2011 Total (1 September 2007 - 31 August 2011) IgE 30 199 32 488 33 520 33 641 129 848 ECP 363 324 314 132 1 133 ImmunoCAP 201 941 244 597 258 104 250 109 954 751 ISAC N/A N/A 309 1 854 2 163 Skin-prick test 14 442 15 902 16 255 15 999 62 598 Total (N) 246 945 293 311 308 502 301 735 1 150 493 N/A = not available; ECP = eosinophil cationic protein; ISAC = Immuno solid-phase allergen chip. Table 2. Diagnosis of acute and chronic sinusitis Acute bacterial sinusitis (ABS) Chronic rhinosinusitis without nasal polyps (CRSsNP) Chronic rhinosinusitis with nasal polyps (CRSwNP) Anterior or post-nasal discharge Anterior or post-nasal discharge Anterior or post-nasal discharge OR OR OR Nasal obstruction ± Facial pain/pressure ± Change in sense of smell Nasal obstruction ± Facial pain/pressure ± Change in sense of smell Nasal obstruction ± Facial pain/pressure ± Change in sense of smell • Lasts >10 days and 12 weeks and no nasal polyps >12 weeks and documented nasal polyps *Acute URTI lasting

[osatobjd]

Сharlie my love <3

[damasquerade]

The long awaited meeting - Pipos O.Charlotte and A.Derek.

[athenaroseannatse]

EEEEE my little Fatty <3 I need to get her a fluffy body suit as soon as possible so that she can look more like a puffy cat XDDDDD And I’m happy to find out how good she looks in these eyes (they belongs to Will but I guess he has to share them now LOL)

[sailorsamus]

Fun fact: the dresses for the 11.5 inch Sailor Moon dolls fit Charlottes (R.Pi) and Cheshires (Pi)!

[osatokun]

Charlie! sweater by @oversee-tblr !