#physical medicine and rehabilitation

[biomedres]

Oxidative Stress Indices and Inflammatory Responses in Female Wistar Rats Administered Acetaminophen, Ampicillin/Cloxacillin and Co-Trimoxazole

Oxidative Stress Indices and Inflammatory Responses in Female Wistar Rats Administered Acetaminophen, Ampicillin/Cloxacillin and Co-Trimoxazole in Biomedical Journal of Scientific & Technical Research

Prescription drugs are frequently purchased from Pharmacy outlets based on selfmedication and often, combined to achieve therapeutic objectives that may trigger drug interactions that have not been fully elucidated. Therefore, this study evaluated the effects of concomitant administration of acetaminophen, ampicillin/cloxacillin and cotrimoxazoleon oxidative and inflammatory responses. Seventy female Wistar rats were assigned into seven groups of ten animals each. Therapeutic doses at 100 mg/kg body weight of co-trimoxazole, and 105 mg/kg body weight each of ampicillin/cloxacillin and acetaminophen orally once daily for four weeks. Group A served as the control, group B was administered ampicillin/cloxacillin only, group C was administered co-trimoxazole only, group D was administered acetaminophen only, group E was administered acetaminophen and ampicillin/cloxaxillin, group F was administered co-trimoxazole and acetaminophen, and group G was administered acetaminophen, ampicillin/ cloxacillin, and co-trimoxazole. Oxidative status was determined in the serum and homogenates of liver and brain by the levels of total thiol, reduced Glutathione (GSH), Oxidized-Low Density Lipoprotein Cholesterol (Ox-LDL-C). Inflammatory response was assessed by measuring the serum levels of Interleukin-1β (IL-1β), Nitric Oxide (NO), Monocyte Chemoatracttant Protein (MCP-1), Vascular Adhesion Molecule (VCAM-1) and Total Immunoglobulin G (IgG). Body weights and organ to body weight ratios across the groups were insignificantly different (p>0.05). Serum total thiol level increased (p<0.05) in B and D compared to A,C, E, F and G. Liver and brain total thiol levels were insignificant changed (p>0.05) across the groups compared to control but increased (p<0.05) in liver of G compared to D and brain of B and D compared to C. Serum GSH levels were insignificantly different (p>0.05) across the groups, while liver GSH in G decreased (p<0.05)compared to A, B, C and D and brain GSH level in F was elevated (p<0.05) compared to A,B,C,D and E. Serum Ox-LDL-C concentrations were elevated significantly (p<0.05) in F and G compared to A and D. Serum levels of IL-1β, NO, MCP-1,VCAM-1 and IgG were insignificant changed (p>0.05) across the groups, but there was decrease (p<0.05) in VCAM-1 in G compared to B. Histological examination indicated varying degrees of vacuolation, fenestration and occlusion in liver, and neurodegeneration in brain of groups administered the drugs. This study showed that the concomitant use of acetaminophen, ampicillin/cloxacillin and co-trimoxazole caused oxidative stress that has a weak link to vascular related disorders. Therefore, awareness of the health implications associated with misuse of these drugs should be emphasized.

For more articles in Journals on Biomedical Sciences click here bjstr

[k-star-holic]

100 million won annual salary + mother's doctor Wanted by mother's conditional birth certificate + child planning + high education (matchmaking)

[newyorkthegoldenage]

Finally able to walk, 3-year-old polio patient Joseph Maldonado leaves NYU's Institute of Rehabilitation and Physical Medicine, where he received polio treatment paid for by the March of Dimes, 1959.

Photo: NY Daily News

[drterryhansenalbuquerque]

Dr Terry Hansen Albuquerque - A Physical Medicine And Rehabilitation Doctor

Dr. Terry Hansen, an experienced Physical Medicine and Rehabilitation doctor based in Albuquerque. Specializing in Spine, Sports Medicine, Orthopedics, Pain Medicine, and Occupational Medicine, Dr. Hansen is committed to eliminating pain and restoring quality of life. His professional inspiration lies in empowering individuals to reach their full potential.

[integrative-rehab-medicine]

Regenerative Spine Treatment  in Estero, Florida

Discover effective treatment for back and neck pain at Integrative Rehab Medicine in Estero, Florida. Our innovative Regenerative Spine Treatment utilizes Platelet Rich Plasma (PRP) and bone marrow stem cells to address various conditions, including bulging discs, arthritis, and sciatica. This non-surgical approach promotes healing and improves spinal health and function. Experience personalized care tailored to your needs. Schedule your consultation today!

[crimson-rehabilitation]

A Good Therapeutic Approach for Patients with Paraparesis due to Spinal Arteriovenous Fistula

 Abstract

Although Spinal Dural Arteriovenous Fistula (SDAVF) is the most common arterio-venous malformation of the spinal cord, it is an extremely rare pathology. It is usually an acquired condition that may cause congestive myelopathy through chronic venous hypertension. The clinical picture is non-specific but the diagnosis can be inferred from Magnetic Resonance Imaging (MRI) and confirmed through Digital Subtraction Angiography (DSA). We report four cases that presented in our clinic in the past twelve months and in which SDAVF was suspected based on spinal MRI. The mean age was 54. Three of them presented with severe motor deficits and two of them had sphincteric disturbances. Sensory deficits varied. Three of the patients had a subacute progression, while one of them evolved rather acutely. The diagnosis was confirmed through DSA with selective catheterization and endovascular occlusion of the feeding artery by injection of liquid embolic material was performed with no periprocedural incidents. There was no further progression of deficits and three of the patients presented partial improvement by the time of discharge. One of the main challenges posed by these patients is correctly identifying the feeding artery of the SDAVF, which may be achieved by spinal Magnetic Resonance Angiography (MRA) and elaborate DSA. Another aspect relates to the recovery of neurologic deficits which includes motor rehabilitation programmes, as well as management of associated symptoms and pathologies. It is our experience that shunt obliteration should be always attempted as SDAVF is a rare but recuperable cause of severe neurologic deficits.

Read more about this article: https://crimsonpublishers.com/epmr/pdf/EPMR.000588.pdf

Read more Crimson Publishers Google Scholar

Articles: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=MAr8S6kAAAAJ&citation_for_view=MAr8S6kAAAAJ:maZDTaKrznsC

[kimshealthrbh]

Physical Medicine & Rehabilitation | KIMSHEALTH Umm Al Hassam

KIMSHEALTH Rehabilitation offers high-quality multidisciplinary rehabilitation services. The department offers inpatient, outpatient and telerehabilitation services as well as home care programs.

[crimson-marine]

What are the Perceived Therapy Needs of Adults Living with Osteogenesis Imperfecta? A Focus Group Study

 Abstract

Background: Osteogenesis Imperfecta (OI) is a rare genetic disorder characterised by fragile bones. Clinical presentation includes multiple health issues which impact on quality of life. There is no published data on what adults with OI perceive their therapy needs to be. 

Objective: This study aims to explore the therapy needs of adults with OI. 

Methods: A convenience sample of adults were recruited from a multidisciplinary OI clinic. Participants were split into two groups based on their clinical classification. Semi-structured questions were asked focusing on perceived needs for therapy. Thematic analysis identified common themes from the data. 

Result: Eleven participants were allocated to two focus groups, ages ranged from 27-68 years. The discussions from both groups elicited similar interconnecting themes of 1) knowledge and expertise, 2) confidence in healthcare services, 3) access to healthcare and community services. There was consensus that therapy was required for adults with OI and treatment was not only for fractures. However, participants valued continuity of care with healthcare professionals who understood OI and where this wasn’t available dissatisfaction with healthcare was identified. Therapy included multiple disciplines reflecting the participants’ wide-ranging needs which reflected a bio-psycho-social framework.

 Conclusion: The results reflect the life-long nature of OI and its impact on quality of life. Participants felt a holistic approach to treatment was the most beneficial due to the complexity and variability of OI. Impact statement: This study demonstrates a need for specialist multidisciplinary services to be commissioned for adults with OI.

Read more about this article: https://crimsonpublishers.com/epmr/pdf/EPMR.000598.pdf

Read more Crimson Publishers Google Scholar

Articles: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=MAr8S6kAAAAJ&citation_for_view=MAr8S6kAAAAJ:TQgYirikUcIC

[biomedres]

Hippocrates to COVID-19

Hippocrates to COVID-19 in Biomedical Journal of Scientific & Technical Research

Since ancient times, human beings considered that the climate has influence on the origin and nature of diseases. The relation between climate and health was first attributed to supernatural forces, till Hippocrates in 460 BC refused all these superstitions, legends, and beliefs. Furthermore, he separated medicine from religion, arguing that diseases were not punishments doled out by mythological gods, but consequences from environmental factors, diet, and health habits. Throughout history difference “schools of thought” were developed differing between those who strive to provide a better climate or environment and those who treat diseases, but both seek more “healthier” places than others and indicate which climate changes can increase the vulnerability of a population to certain pathologies. Hippocrates indicated in one of his writings called “Aphorisms” the following:

1. Aphorism 3: Of diseases and ages, certain of them are well- or ill-adapted to different seasons, places, and kinds of diet.

2. Aphorism 19: All diseases occur at all seasons of the year, but certain of them are more apt to occur and be exacerbated at certain seasons.

For more articles in Journals on Biomedical Sciences click here bjstr

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[k-star-holic]

"Doctor Mossol" "Marriage? Mom must meet Jessie's conditions"

[biwenmd]

Pressure Injury Prevention: S.S.K.I.N

[beltwaymedicalgroup]

The Role of Sports Medicine in Enhancing Physical Activity Levels

Physical activity plays a pivotal role in maintaining overall health and well-being. Engaging in regular exercise and sports not only strengthens the body but also has numerous mental and emotional benefits. However, participation in physical activities can sometimes lead to injuries or other health issues. This is where sports medicine comes into play, offering a comprehensive approach to enhancing physical activity levels while minimizing the risk of injuries. 

Understanding Sports Medicine:

Sports Medicine Fairfax VA is a specialized branch of medicine that focuses on the prevention, diagnosis, treatment, and rehabilitation of injuries related to sports and exercise. It encompasses various disciplines, including sports science, orthopedics, physiology, biomechanics, nutrition, and physical therapy. The primary goal of sports medicine is to optimize performance, prevent injuries, and facilitate the safe return to activity following an injury.

Prevention of Injuries:

One of the fundamental aspects of sports medicine is injury prevention. Sports medicine professionals work closely with athletes and individuals engaging in physical activities to identify potential risk factors and develop strategies to mitigate them. This may involve assessing biomechanics, addressing muscle imbalances, improving flexibility and strength, and providing education on proper training techniques and equipment use. By implementing preventive measures, sports medicine helps individuals reduce the likelihood of sustaining injuries during exercise or sports participation, thus enabling them to engage in physical activities more safely and consistently.

Diagnosis and Treatment:

Despite preventive efforts, injuries can still occur. Sports medicine specialists are trained to accurately diagnose sports-related injuries and develop customized treatment plans tailored to each individual's needs. Whether it's a sprain, strain, fracture, or other musculoskeletal issue, prompt and accurate diagnosis is crucial for effective treatment. Sports medicine utilizes various diagnostic tools, such as imaging studies (X-rays, MRI scans), physical examinations, and functional assessments, to determine the extent and nature of the injury. Treatment modalities may include rest, physical therapy, medication, bracing or taping, and in some cases, minimally invasive or surgical interventions. By addressing injuries promptly and effectively, sports medicine helps individuals recover faster and return to their desired level of physical activity with minimal complications.

Performance Optimization:

In addition to injury prevention and treatment, sports medicine plays a vital role in optimizing athletic performance. Sports scientists and performance coaches collaborate with athletes to enhance their strength, speed, agility, endurance, and overall athletic capabilities. This may involve individualized training programs, nutritional counseling, biomechanical analysis, mental skills training, and recovery strategies. By maximizing performance potential, sports medicine enables athletes to excel in their respective sports and achieve their goals while minimizing the risk of overtraining or burnout.

Rehabilitation and Return to Activity:

Physical Therapy Fairfax VA is an integral part of sports medicine, focusing on restoring function, mobility, and strength following an injury or surgery. Sports medicine professionals work closely with patients throughout the rehabilitation process, providing personalized exercise programs, manual therapy, modalities (e.g., heat, ice, electrical stimulation), and progressive training to facilitate optimal recovery. The goal of rehabilitation is not only to heal the injured area but also to address underlying issues, prevent recurrence, and ensure a safe return to physical activity. Through comprehensive rehabilitation protocols, sports medicine helps individuals regain confidence in their bodies and resume their active lifestyles with resilience and efficiency.

Promotion of Healthy Lifestyles:

Beyond injury management and performance enhancement, sports medicine plays a crucial role in promoting healthy lifestyles and physical activity participation across diverse populations. Sports medicine professionals engage in community outreach programs, educational initiatives, and advocacy efforts to raise awareness about the importance of regular exercise, proper nutrition, injury prevention, and overall well-being. By empowering individuals with knowledge and resources, sports medicine contributes to the creation of healthier communities and fosters a culture of lifelong physical activity and wellness.

Facilitating Rehabilitation

Sports medicine plays a multifaceted role in improving physical activity levels and enhancing overall health and performance. From preventing injuries and diagnosing/treating sports-related conditions to optimizing performance, facilitating rehabilitation, and promoting healthy lifestyles, sports medicine encompasses a comprehensive approach to supporting individuals in their pursuit of active living. By leveraging the expertise of various disciplines and applying evidence-based practices, sports medicine contributes significantly to the well-being and success of athletes and physically active individuals across the lifespan. As we continue to recognize the importance of physical activity in maintaining health and vitality, the role of sports medicine remains indispensable in ensuring safe, effective, and enjoyable participation in sports and exercise.

Advances in medical technology

Sports medicine professionals, including physicians, researchers, and scientists, actively contribute to ongoing research efforts aimed at understanding the mechanisms of injury, optimizing treatment strategies, and developing new technologies and interventions to improve outcomes. Through clinical trials, epidemiological studies, biomechanical research, and advances in medical technology, sports medicine continues to evolve, offering innovative solutions to enhance physical activity participation and promote better health outcomes. By staying at the forefront of scientific inquiry and technological advancements, sports medicine not only improves current practices but also paves the way for future breakthroughs in injury prevention, rehabilitation, performance optimization, and overall wellness.

[crimson-rehabilitation]

Multiple Sclerosis: Relationships between Locus of Control, Coping Strategies and Quality of Life

 Abstract

Multiple Sclerosis (MS) is a chronic, inflammatory, demyelinating disease affecting the central nervous system. It usually presents with a variety of physical, cognitive, and psychological signs and symptoms. The normal course of illness, unpredictable, leads patients to an inevitable reactive condition that affects their family and their own life. It is believed that individual persuasions about the ability to manage the events of life has direct consequences on the control of life itself, above all on treatment and medical care compliance. The aim of this study was to investigate the relationship between locus of control and the impact of psychological features in the choice of coping strategies in patients affected by MS and their influence on Quality of Life (QoL). For this reason, we enrolled 87 patients (66,7% women, 33.3% men; mean age 42.1) affected by relapsing–remitting multiple sclerosis according to Mc Donald’s criteria and with disability corresponding to a mean score of 2.2 on Expanded Disability Status Scale (EDSS). Participants were followed periodically at our Multiple Sclerosis Centre. QoL was assessed using the SF36 questionnaire. Clinical disease progression was evaluated using EDSS; locus of control was used as a psychological variable. Numerical data were expressed as mean and standard deviations, categorical variables as number and percentage. The results demonstrated that patients with an external locus of control had lesser perception of physical pain (p=0.0003), vitality (p=0.019), social activity (p=0.0022), physical condition indicator (p=0.017) and disease status indicator (p=0.019). On the other hand, internal locus decreased the “mental health” perception (p=0.006) and the disease status index (p=0.018). The clinical relevance of the relationship between QoL and locus of control is very important because it may provide information about the general health status of patients and can also help physicians to choose the best treatment option, mostly considering the significant role of therapy adherence.

Read more about this article: https://crimsonpublishers.com/epmr/pdf/EPMR.000587.pdf

Read more Crimson Publishers Google Scholar

Articles: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=MAr8S6kAAAAJ&citation_for_view=MAr8S6kAAAAJ:k_IJM867U9cC