#non-infectious disease
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jppres · 2 years ago
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Activation of microvesicle peripheral blood mononuclear cells by mesenchymal stem cells secretome co-cultivated with osteosarcoma stem cell
Article published in J. Pharm. Pharmacogn. Res., vol. 10, no. 5, pp. 782-790, September-October 2022. DOI: https://doi.org/10.56499/jppres22.1414_10.5.782 Fachrizal Arfani Prawiragara1,2, Ferdiansyah2*, Mouli Edward2, Dwikora Novembri Utomo2, Mohammad Hardian Basuki2, Alexander Patera Nugraha3, Fedik Abdul Rantam4 1Magister Clinical Medicine Program, Orthopedic and Traumatology Department,…
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rahulp3 · 5 months ago
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What Are The Major Factors Driving Retinal Biologics Market Growth?
The Retinal Biologics Market is experiencing a surge in demand, fueled by advancements in eye disease treatments and a growing emphasis on vision health. According to a recent analysis by Future Market Insights (FMI), a leading market research firm, the market is currently valued at an impressive US$22.25 billion in 2022. Looking ahead, the market is projected to witness a remarkable Compound Annual Growth Rate (CAGR) of 11.1% over the next six years. This translates to a staggering market valuation of US$41.92 billion by 2028, highlighting the significant potential of retinal biologics in revolutionizing eye care.The remarkable expansion of the Global Retinal Biologics sector is fueled by advancements in technology, innovative research, and a growing demand for cutting-edge treatments. As the industry continues to evolve, it presents unprecedented opportunities for stakeholders, investors, and healthcare professionals alike.Key Retinal Biologics Market Insights:
Rising Prevalence of Diabetes-related Eye Disorders and Age-related Macular Degeneration (AMD) The prevalence of diabetes-related eye disorders and age-related macular degeneration is on the rise, underscoring the growing need for innovative solutions within the Retinal Biologics Industry.Substantial Investment in R&D for Biologics in Retinal Disorders The industry is witnessing a significant influx of research and development resources, aimed at advancing biologics for both infectious and non-infectious retinal disorders. This investment underscores the commitment to addressing unmet medical needs.
Emergence of Specific Biologic Molecules as Therapeutic Targets Specific biologic molecules are gaining prominence as highly promising therapeutic targets, offering new hope for patients with retinal conditions.Gene Therapy as a Solution for Monogenic Retinal Illnesses With a growing number of monogenic retinal illnesses, gene therapy is emerging as a pivotal component of the Retinal Biologics Market, presenting innovative solutions for these challenging conditions.
Request a Sample Copy of This Report Now.https://www.futuremarketinsights.com/reports/sample/rep-gb-8663
#The Retinal Biologics Market is experiencing a surge in demand#fueled by advancements in eye disease treatments and a growing emphasis on vision health. According to a recent analysis by Future Market I#a leading market research firm#the market is currently valued at an impressive US$22.25 billion in 2022. Looking ahead#the market is projected to witness a remarkable Compound Annual Growth Rate (CAGR) of 11.1% over the next six years. This translates to a s#highlighting the significant potential of retinal biologics in revolutionizing eye care.The remarkable expansion of the Global Retinal Biol#innovative research#and a growing demand for cutting-edge treatments. As the industry continues to evolve#it presents unprecedented opportunities for stakeholders#investors#and healthcare professionals alike.Key Retinal Biologics Market Insights:Rising Prevalence of Diabetes-related Eye Disorders and Age-relate#underscoring the growing need for innovative solutions within the Retinal Biologics Industry.Substantial Investment in R&D for Biologics in#aimed at advancing biologics for both infectious and non-infectious retinal disorders. This investment underscores the commitment to addres#offering new hope for patients with retinal conditions.Gene Therapy as a Solution for Monogenic Retinal Illnesses With a growing number of#gene therapy is emerging as a pivotal component of the Retinal Biologics Market#presenting innovative solutions for these challenging conditions.Request a Sample Copy of This Report Now.https://www.futuremarketinsights.#institutional sales in the Retinal Biologics Industry#where Retinal Biologics are supplied in speciality clinics and hospitals#will generate higher revenues. In 2018#hospital sales accounted for more than 35% of market revenue.According to the report#retail sales of Retinal Biologics will generate comparable revenues to hospital sales and will expand at an 11.9% annual rate in 2019. Reta#with retail pharmacies generating more money than their counterparts in the future years.Penetration in North America Higher#APEJ’s Attractiveness to IncreaseNorth America continues to be the market leader in Retinal Biologics revenue. According to FMI estimates#North America accounted for more than 46% of global Retinal Biologics Industry revenues in 2018. Revenues in North America are predicted to#continuous growth in the healthcare infrastructure#and a favourable reimbursement scenario.Europe accounted for about one-fourth of the Retinal Biologics market#with Western European countries such as Germany#the United Kingdom#France#Italy
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news-buzz · 19 days ago
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US will get D+ grade for rising preterm delivery charges, new report finds
CNN  —  The speed of untimely delivery in america is climbing, based on the toddler and maternal well being nonprofit March of Dimes. On Tuesday, the group launched its annual “report card” on maternal and toddler well being, which entails a newly up to date calculation system. Taking an in-depth take a look at untimely births, the brand new report discovered that the US preterm delivery fee…
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ripley-ryan · 1 year ago
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GUESS WHO CAN AFFORD HER MEDICATION
it’s just subcutaneous methyl b-12 injections but i really do need to get my levels up to a healthy number
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batboyblog · 4 months ago
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Things the Biden-Harris Administration Did This Week #28
July 19-26 2024
The EPA announced the award of $4.3 billion in Climate Pollution Reduction Grants. The grants support community-driven solutions to fight climate change, and accelerate America’s clean energy transition. The grants will go to 25 projects across 30 states, and one tribal community. When combined the projects will reduce greenhouse gas pollution by as much as 971 million metric tons of CO2, roughly the output of 5 million American homes over 25 years. Major projects include $396 million for Pennsylvania’s Department of Environmental Protection as it tries to curb greenhouse gas emissions from industrial production, and $500 million for transportation and freight decarbonization at the ports of Los Angeles and Long Beach.
The Biden-Harris Administration announced a plan to phase out the federal government's use of single use plastics. The plan calls for the federal government to stop using single use plastics in food service operations, events, and packaging by 2027, and from all federal operations by 2035. The US government is the single largest employer in the country and the world’s largest purchaser of goods and services. Its move away from plastics will redefine the global market.
The White House hosted a summit on super pollutants with the goals of better measuring them and dramatically reducing them. Roughly half of today's climate change is caused by so called super pollutants, methane, hydrofluorocarbons (HFCs), and nitrous oxide (N2O). Public-private partnerships between NOAA and United Airlines, The State Department and NASA, and the non-profit Carbon Mapper Coalition will all help collect important data on these pollutants. While private firms announced with the White House plans that by early next year will reduce overall U.S. industrial emissions of nitrous oxide by over 50% from 2020 numbers. The summit also highlighted the EPA's new rule to reduce methane from oil and gas by 80%.
The EPA announced $325 million in grants for climate justice. The Community Change Grants Program, powered by President Biden's Inflation Reduction Act will ultimately bring $2 billion dollars to disadvantaged communities and help them combat climate change. Some of the projects funded in this first round of grant were: $20 million for Midwest Tribal Energy Resources Association, which will help weatherize and energy efficiency upgrade homes for 35 tribes in Michigan, Minnesota, and Wisconsin, $14 million to install onsite wastewater treatment systems throughout 17 Black Belt counties in Alabama, and $14 million to urban forestry, expanding tree canopy in Philadelphia and Pittsburgh.
The Department of Interior approved 3 new solar projects on public land. The 3 projects, two in Nevada and one in Arizona, once finished could generate enough to power 2 million homes. This comes on top of DoI already having beaten its goal of 25 gigawatts of clean energy projects by the end of 2025, in April 2024. This is all part of President Biden’s goal of creating a carbon pollution-free power sector by 2035. 
Treasury Secretary Janet Yellen pledged $667 million to global Pandemic Fund. The fund set up in 2022 seeks to support Pandemic prevention, and readiness in low income nations who can't do it on their own. At the G20 meeting Yellen pushed other nations of the 20 largest economies to double their pledges to the $2 billion dollar fund. Yellen highlighted the importance of the fund by saying "President Biden and I believe that a fully-resourced Pandemic Fund will enable us to better prevent, prepare for, and respond to pandemics – protecting Americans and people around the world from the devastating human and economic costs of infectious disease threats,"
The Departments of the Interior and Commerce today announced a $240 million investment in tribal fisheries in the Pacific Northwest. This is in line with an Executive Order President Biden signed in 2023 during the White House Tribal Nations Summit to mpower Tribal sovereignty and self-determination. An initial $54 million for hatchery maintenance and modernization will be made available for 27 tribes in Alaska, Washington, Oregon, and Idaho. The rest will be invested in longer term fishery projects in the coming years.
The IRS announced that thanks to funding from President Biden's Inflation Reduction Act, it'll be able to digitize much of its operations. This means tax payers will be able to retrieve all their tax related information from one source, including Wage & Income, Account, Record of Account, and Return transcripts, using on-line Individual Online Account.
The IRS also announced that New Jersey will be joining the direct file program in 2025. The direct file program ran as a pilot in 12 states in 2024, allowing tax-payers in those states to file simple tax returns using a free online filing tool directly with the IRS. In 2024 140,000 Americans were able to file this way, they collectively saved $5.6 million in tax preparation fees, claiming $90 million in returns. The average American spends $270 and 13 hours filing their taxes. More than a million people in New Jersey alone will qualify for direct file next year. Oregon opted to join last month. Republicans in Congress lead by Congressmen Adrian Smith of Nebraska and Chuck Edwards of North Carolina have put forward legislation to do away with direct file.
Bonus: American law enforcement arrested co-founder of the Sinaloa Cartel, Ismael "El Mayo" Zambada. El Mayo co-founded the cartel in the 1980s along side Joaquín "El Chapo" Guzmán. Since El Chapo's incarceration in the United States in 2019, El Mayo has been sole head of the Sinaloa Cartel. Authorities also arrested El Chapo's son, Joaquin Guzman Lopez. The Sinaloa Cartel has been a major player in the cross border drug trade, and has often used extreme violence to further their aims.
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unganseylike · 2 years ago
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had a deeply confusing interview i had to do on my phone bc my laptop camera broke last minute. where they literally didnt ask me any questions and basically offered me the position at the end
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dreamescapeswriting · 7 months ago
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Petals Of Love ~ HJS
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WORD COUNT: 2.9K
GENRE: Non idol, college au, established friendships, unrequited love, jisung blind to his feelings, reader almost dying, mentions of coughing and blood, hanahaki disease [Hanahaki disease is a fictional medical condition often depicted in anime, manga, and fan fiction. It's characterized by the symptoms of coughing up flower petals or blossoms due to unrequited love. ]
PAIRING: Jisung X Fem!Reader
⤜Copyright: © DreamEscapesWriting - April 2024
⤜MASTERLIST
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In the bustling city of Seoul, cherry blossoms painted the streets pink, and everywhere you went petals fell down and showered those around them creating a beautiful scene, but you hated it. 
You had once loved the flowers but now they simply reminded you of the one person you could never have, the one person that was killing you slowly on the inside and didn't even know it. Your best friend. Jisung.
You'd always loved him but you hadn't realised the depth of your feelings until recently. It had started subtly, with you admiring his infectious laugh or his giant smile. The way he stored food in his cheeks or his passion for music. Everything about him drew him in. He even had a remarkable ability to see the best in people and bring joy to those around him mostly you.
"Dear? Is there something I can do for you?" A voice brought you out of your daydream as you slowly turned around to face an elderly woman who was staring at you. You took in her appearance, silver hair that cascaded down her back in gentle waves and she was dressed in a headscarf adorned with cherry blossoms. You'd been reading about her all week long, she was supposed to be the best herbalist in all of Seoul and you figured she'd be able to find a way to help you.
"I...I need your help," You stuttered, your voice barely above a whisper, and your hands were trembling.
"I have this... this illness. It's called Hanahaki. I'm in love with my best friend, Jisung, but... but he doesn't feel the same way. I'm coughing up petals, and I don't know what to do." Tears sprang to your eyes as you finally admitted it out loud to someone else. Ever since you'd started coughing up the petals you'd done everything you could to hide it, not wanting anyone to see you. 
The herbalist listened attentively, her expression softening as she heard your plight. With a gentle touch, she reached out to comfort you.
"I'm sorry, my dear," the herbalist sighed, her voice heavy with regret. 
"But there is little I can do for you. Hanahaki is a curse born of unrequited love, and its remedy lies not in herbs or potions, but in the depths of your heart." Your heart sank at the herbalist's words, your hopes dashed against the harsh reality of your situation. Tears welled up in your eyes as you realized the gravity of your predicament. 
"But... but there must be something!" You pleaded, desperation lacing your voice. 
"I can't just let this disease consume me. Jisung... he means everything to me. I can't lose him." The herbalist's gaze softened, her eyes reflecting your anguish.
"My dear child," she murmured, her voice gentle yet firm. 
"Sometimes, the greatest remedies come not from external sources, but from within ourselves. Only by confronting your feelings and expressing them honestly can you hope to find peace, whether it be in love returned or in letting go." With those words, the herbalist offered you a comforting embrace, a silent reassurance that you were not alone in your struggle.
"Confess your love and hope for reciprocation or face the consequences of a love unspoken." She told you softly as she rubbed the small of your back, the weight of everything pressing down on you as you began your walk back to your shared apartment with Jisung. 
No matter how much you adored Jisung there was always someone else for him, someone he liked more than you. The thought of it made your throat close up until you coughed a little, petals falling into your hands, the beautiful pink in stark contrast to the blood red that covered them. 
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As you stepped into the apartment, you were instantly greeted by the scent of your home and Jisung running around excitedly, his energy infectious as it always was. The thoughts and problems of your day melted away instantly as he grinned in your direction,
"You're back!" He exclaimed, his eyes bright with excitement.
"I have some exciting news!" Curiosity piqued you set your bag down on the floor and walked toward him,
"What's the news?" You smiled.
"I met someone, her name is Emi and she's incredible! You have to meet her!" Your heart skipped a beat, a pang of longing shooting through you as you processed his words. It honestly felt as though it was going to be anyone but you at this point and your chest tightened, your throat burning as you felt the flowers making their way up making it feel as though you were going to choke. Forcing a smile onto your face you nodded,
"T...That's wonderful, I can't wait to meet her," You lied, doing your best to mask the ache in your chest as you spoke. It would be a while before you'd ever have to face her, Jisung was always slow when it came to relationships and never wanted to rush anything. 
"Great! Chan is hosting a party tonight and she'll be there! I can't wait for you to meet her," Your smile faltered as you stared at him, this was faster than any of the past relationships he'd had. 
"Tonight? But-" You didn't even have time to come up with some kind of excuse not to come. 
"It'll be fun, I heard Lix is going to be there." He wiggled his eyebrows at you, he'd been trying to set you up with his friends for a while not catching that you weren't into them but rather him.
"Sounds good," You lied through your teeth, you could think of a million different places you wanted to be rather than at a party where you would watch him with someone else, hell being one of those places. 
"You're the best, this is going to be so much fun!" He told you, embracing you in a tight hug as you squeezed your eyes shut, enjoying the fleeting moment of being so close to him while it lasted. 
"Why not me," You whispered to yourself as he walked away from you, going to plan an outfit for the night and you coughed into your hand throwing away the petals into the bin.
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The party pulsated with energy, its atmosphere electric with excitement and anticipation. Held in Chan's college house adorned with twinkling fairy lights and draped with cascading cherry blossom garlands, it resembled a scene straight out of a fairy tale. The sight of the garlands felt as though they were torturing you though, as if they were there to remind you of your unrequited love.
The air was alive with the sound of laughter and animated conversations, mingling with the rhythmic beat of music that reverberated through the room.
"This is exciting, right?" Jisung asked from beside you, the two of you went to almost all of Chan's parties and this one certainly felt more extravagant than the others that you'd been to in the past.
"Yeah it's nice," You whispered, letting your eyes linger on him for a second enjoying the way his eyes were lighting up at the sight of the party. 
"Might be his best party yet," Jisung chuckled, nudging you softly as you nodded at him but you were in complete awe of him not to agree with everything he was saying. You forced a smile on your face, your heart pounding as you followed Jisung through the throng of partygoers. You tried to focus on the lively atmosphere, the music to try and drown out the whispers of doubt in your mind. 
"Hey! Yn! Jisung!" Felix waves at you both and you smile, hugging him softly and relaxing as he whispers in your ear,
"Missed you little one," The two of you were close with one another, not in a romantic way but still close nonetheless.
"Have you seen Emi anywhere?" The mention of her name had you choking up as you stared at Felix, 
"She was with Chan last I saw her." Without a second thought, Jisung left you and Felix alone, your eyes staring off after your best friend as you swallowed the nervous lump in your throat. 
"She's the girl of the week then?" Felix teased softly, it was no secret that Jisung fell in love with a new girl faster than anyone else but it was something you found endearing about him. 
"I guess so," You mumbled, reaching for a cup from a nearby tray and downing it instantly trying to forget everything that was going to happen tonight.
The two of you fell into casual conversation, catching up with one another as you walked through the party, your eyes finding Jisung instantly as you noticed just how close he was to Emi. Their hands linked with one another as you stared at him a sharp pang of pain shot through your chest, causing you to gasp for breath and clutch onto Felix.
A delicate petal, stained with blood fluttered from your lips, a cruel reminder of the curse that plagued your heart. Felix's eyes widened in shock as he stared at you,
"You okay?" He asked, his voice laced with worry as he pulled you to the side, trying to get you out of the crowded party. Your cheeks were burning with embarrassment as you tried to compose yourself,
"I-I'm fine," You stammered, your voice trembling a little.
"It's nothing." You lied, but Felix's eyes remained fixed on you, his eyes filled with understanding as he realised what was happening.
"You're in love with him, aren't you?" He asked as you stared at him, your breath caught in your throat as you nodded silently, unable to find the words to express the depth of your emotions.
"You can't tell him," You begged, your hands clutching onto Felix's forearms as petals began to fall from your lips faster than before, more blood coating them with each falling petal.
"Yn, it'll kill you if he doesn't know." Something you already knew but even if you told him and he rejected you, you were going to die, you were fighting it as much as you possibly could.
"It'll kill me faster if he knows and rejects me," You croaked out, tears streaming down your cheeks as you shook your head. You'd thought about confessing a million times before, you'd written songs, letters, and poems but nothing was ever going to work because you knew he would never love you back.
"But-"
"There's nothing I can do Lix, either way I die." You mumbled, wiping the corners of your lips to remove the blood from them, sighing a little as you shrugged your shoulders.
"How do you know he doesn't love you?" You scoffed a little and shook your head, there was no way Jisung returned the feelings you had for him,
"He would have said something." You mumbled a little, looking down at the floor as Felix stared at you,
"Like you have to him?" He had you there but you just shook your head, 
"I'm going to get some fresh air, keep him distracted...I don't want to meet Emi," You admitted as Felix nodded, always having your back no matter what.
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The moon cast a gentle glow upon the garden, its silvery light dancing among the cherry blossoms like ethereal spirits. You stood at the threshold, your heart heavy with the weight of unspoken words and unrequited love. Each step felt like a burden, and your chest constricted with the pain of the Hanahaki disease.
With each laboured breath, you coughed, delicate petals stained with blood escaping your lips like crimson tears. The air was thick with the scent of cherry blossoms, their sweet fragrance mingling with the coppery tang of blood—a haunting reminder of the curse that plagued your heart.
As you stumbled forward, your vision blurred with tears, and the world around you seemed to spin, a dizzying whirlwind of colours and sensations. Your strength waned with each passing moment, your body growing weaker with every faltering step.
But still, you pressed on, driven by a desperate longing to be alone with your thoughts, to find solace amidst the tranquil beauty of the garden. Each petal that fell from your lips was a silent plea, a silent prayer for forgiveness and understanding. Darkness began to cloud your vision as you leaned up against a tree, trying to catch as much breath as you could but it was as though there was a filter to your lungs, stopping any viable air coming through.
In that moment of quiet surrender, you finally found peace—a fleeting glimpse of serenity amidst the chaos of your suffering. And as the night stretched on, the garden whispered its mournful lament, a solemn witness to the beauty of love unspoken and the tragedy of a life cut short.
"Have you seen Yn? I figured we'd go home together," Jisung said as he joined Felix in the kitchen but he shook his head,
"She was going for air the last I saw her," He admitted, he hadn't seen you for at least an hour now and he figured you'd gone home. Jisung smiled weakly and began to make his way through the people, his date with Emi couldn't have gone worse, it turned out she had a crush on Chan instead of Jisung and all he wanted was to go home and watch bad movies with you.
"Yn?!" He called out to the party, sighing a little at the thought of you going home alone. The two of you always went home together, dates or not. As he walked through the party, a hushed whisper reached his ears, a rumour that someone had been found unconscious in the garden. Panic built inside of him as he dashed toward the garden, his heart pounding with fear.
As he burst through to the garden his worst fears came true, you were lying on the floor surrounded by cherry Blossoms as people simply stared at you in awe. You were frail on the floor, a halo of petals surrounding you like a mournful shroud.
"Yn!" He cried out, his voice trembling with anguish as he rushed to your side, his hands trembling as he brushed bloodied petals from your chest. Your eyes fluttered open, your gaze clouded with pain as you struggled to breathe,
"Yn," He whispered, his voice choked on emotion. Tears welled in Jisung's eyes as he took in the sight of your frail form, the severity of the situation finally sinking in.
"Oh, Yn," Jisungwhispered, her voice choked with emotion, the thought of all of this happening to you.
"What happened? Why didn't you tell me?" He pleaded with you, the sound of distant sirens blasting through the air, your response was a weak cough, a delicate petal stained with blood escaping your lips—a silent testament to the depth of your suffering. 
Realization dawned upon Jisung like a bolt of lightning, illuminating the darkness of his ignorance. He'd been blind to your silent struggle, oblivious to the agony hidden beneath your friend's smiles and laughter.
"I'm so sorry," He murmured, his voice trembling with regret as tears streamed down his cheeks. 
"I didn't know... I didn't realize..." With each passing moment, your strength waned, your breaths growing shallower as the petals threatened to suffocate your fragile lungs. 
"I wrote a letter and threw it away, 'cause god just knows that I'll never say I think about you every day...I-I know you'll never see me that way." You coughed out before everything faded to black, Jisung's hands shaking you as he begged you to come back to him. 
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"Yn...Yn, can you hear me?" The voice was gentle yet urgent, pulling you back from the brink of oblivion. With a faint groan, you stirred, your eyes fluttering open as you squinted a little.
"Jisung?" You mumbled, your voice hoarse from how dry your throat was. 
"You're in the hospital, you collapsed," Jisung whispered, his hands griping yours with trembling hands, you stared at him and took in his appearance, it looked like he'd barely slept and his eyes were bloodshot.
"What...What happened?" You thought for sure you would have died right then and there, it had been the only reason you'd admitted your feelings to him.
"You were coughing up blood...petals...Yn, why didn't you just tell me?" He squeezed your hand and you shook your head, looking back on it, it all seemed silly not to tell him the truth.
"I was scared I was going to lose you," You admit as you slowly sat up in the bed,
"And I nearly lost you," He choked, kissing your hand softly as you watched him,
"How am I-"
"Alive? After you passed out...I finally realised I love you, I always have and I just cried into your chest," He laughed nervously and wiped the tears away from his cheeks.
I've loved you for as long as I can remember. I just didn't know how to tell you." He admitted as you stared at him in complete shock,
"You saved my life," You whispered as you swallowed and for the first time in forever it didn't hurt, it felt pain-free as you finally didn't feel the urge to cough anymore.
"I love you, Jisung." You whimpered a little./
"I love you too, Yn," He whispers, leaning down and kissing you softly as you wrap your arms around the back of his neck bringing him closer to you.
In that moment, amidst the sterile walls of the hospital room, you felt a weight lift from your chest—a burden lifted by the power of love and the courage to speak your truth. And as Jisung leaned in to press a gentle kiss to your forehead, you knew that this was exactly where you belonged—in the arms of the man you loved, your heart finally at peace.
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words-of-wolf · 20 days ago
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One thing I think about sometimes is like... maybe humans would be better at being people if we all were comfortable viewing ourselves as a type of animal, y'know?
Being a therian, I kinda do this by default. I'm a wolf, of course I'm just an animal! But it's funny how much is applicable to human-identifying folks as well?
Being able to recognise non-judgementally when a thing you are feeling is an animal instinct -- irrational, imperfect, something to be approached with gentleness but not naivety, like a scared little bird trapped in a house which you (unbeknownst to the bird) only wish to help -- is so healing, I think.
Sometimes I feel scared and it's not a "person fear" but it's also not a "wolf fear" -- it's a human-animal fear. An animal instinct that humans possess, a relic of a time when our ancestors were not quite people yet, or lived in situations vastly different than we do now.
I think a lot of peoples' fear of others who are different stems from that kind of thing.
Like, there's often this fear that those who are weird are "ill" or "dangerous" in some way. That's an instinct.
For an animal, it sometimes pays to be wary of something acting strangely, because there are infectious diseases that can cause that.
But the holdover of that fear doesn't serve much purpose for us when we can just talk, and listen, and learn.
That person who's making you uncomfortable doesn't have rabies, y'know? Your mind is telling you to be scared because maybe they have rabies! But you, rational-minded you, knows for a fact that that instinct is wrong.
It's not difficult to recognise these things, once you open your mind enough to your own natural behaviours.
But it's not bad to have instincts. We're all animals, therian or not. I'm a wolf animal but I'm also a human animal.
Humans have plenty of great instincts too. Humans are far more compassionate than wolves, that's for sure! It's a natural instinct for humans to want to help each other, and even other animals! That's really special, and awesome.
That's one of the reasons I think it's important to be gentle when you recognise the instincts of the animal that is you. Being an animal isn't bad. There's a lot of value in our capacity to feel.
It's just also helpful to be able to observe your instincts to learn to recognise when they're not helpful, or needed. And in that case, you can still be gentle with yourself.
It's okay, little bird, that person acting strangely isn't going to hurt you. You don't need to feel scared. They're a person, just like you.
[Note: if you respond to this most with misanthropy, I'm just gonna block you. Don't have the energy to deal with that rn. '^^]
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writingwithcolor · 11 months ago
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Dark features/people as blessed, white and light people as sick
ladyoftheseastuff asked:
I'm writing a fantasy story where the world is permanently covered in snow & ice. The people share a common culture & are loyal to their city states, but they are not homogeneous in appearance; there will be many, many characters coded as PoC. The main religion centers on the sun, & those with dark features are 'favoured' by the sun god, while pale people or anyone who has white/blonde hair are thought vulnerable to "snow sickness", a disease caused by environmental factors (1/2) & have other rules and customs to gain religious approval. It's dangerous & infectious but not well understood. It affects social standing and opportunities, but it's meant to be tied with ideas of youth, vitality, & fear of aging & sickness: it's not limited to those coded as white. This is a cultural detail and not part of the main conflict, but I want to avoid unintentional allegories/parallels & fetishization. Is this a concept that's too close to crossing any of those lines? (2/2)
This feels less like a means to show dark skinned people in an empowering light and more like a weak attempt at subversion. My primary concern (which you have not specified) is how do the "blessed" class treat the "sickly" so to speak. We have fantasy stories like The Grisha Trilogy and Girls of Paper and Fire, which deal with magical ability/feature-based segregation and conflict.
In both cases there is a sense of entitlement which comes with hailing from the "favoured" class, quite obvious, since there will always be an inherent othering metaphor whenever you create such a division, whether it was meant to be a source of conflict or not.
However, the two mentioned series use the "magical people are blessed, non magical people are to be pitied" arc which is somewhat more subtle than divisions created just on the basis of skin colour.
Disclaimer as I do not have albinism or vitiligo: The latter can be extremely harmful, and not just in a racial context, but in cases of albinism, vitiligo etc.
~Mod Mimi
The pitfalls of subversions
While it is always lovely to see dark features considered in a favorable way, there are some issues you may come across. Such a story could easily end up dressing those you wished to uphold as bad guys in the readers' eyes, even if the story's society and the sun god etc. thinks they're amazing, and white and light people as the victims of dark people, deserving reader sympathy. This may especially be the case based on how these groups get treated in the story.
These sort of subversions lean dangerously into "reverse discrimination" plots which are not overall accurate or favorable allegories for your real, human audience. There being diversity on both sides doesn't necessary fix this issue or remove racial or ethnic implications. On that note, and as Mimi mentioned, being demonized and ostracized particularly for skin and genetic disorders like albinism is already a thing. What does your concept say of them?
I think Dark/Black as good and Light/white as bad is a doable concept. Your concept differs a bit from simply subverting black/white tropes. This is not just Black good guys and night skies being peaceful or neutral. It's not just white/light villains (as opposed to victims) or snow symbolling death or sickness.
White and light people are quite blatantly being declared as sick and unfavored and they may very well be victims in the reader's eye with the dark people being the villainous, unsympathetic bunch. Is this your intention?
More to consider
Such a concept requires thoughtful, careful planning and intentional writing. You should have an understanding of what your story implies to the readers and the real-life takeaways.
I think it's possible to make dark skin the favored skin of the sun god without it meaning white/light people stand in a negative light and are sick or unworthy.
Consider what it is that you like about the concept of your story. Can you keep the essence of whatever it is that excites you about your ideas, without denying a whole group of people favor? If not, how will you go about telling such a tale that is not meant to symbolize a sort of reversal of roles discrimination?
Why does the sun god get to determine what is good?
Are there other gods that might have different strong opinions? Perhaps who is favored varies by time of day, season, region, culture, god?
Can dark skin get its favor without white and light features being deemed unfavorable as a whole?
How big of a deal does this favor have to be? I advise reconsidering it being the point of discrimination to white/light people for all the reasons already described.
No matter the directions you go, please research and get the appropriate beta-readers for feedback on the in-depth concepts and story.
~Mod Colette
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covid-safer-hotties · 1 month ago
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Also preserved on our archive
Swab, swirl, squirt, sit tight. By now, you’re likely familiar with the ritual of performing a COVID test at home or on the go. Disease detection has evolved swiftly since 2020, when you may have had to seek out a pop-up testing clinic or wait hours in line at your local health department, with clinicians on standby to stick a cotton swab up your nose.
Rapid COVID tests have since become a staple of cough-and-cold aisles across America, and just weeks ago the federal government resumed its periodic distribution of four free tests per household. But the convenience of self-testing comes with a caveat: The onus is on you to report your results.
First, know that test reporting isn’t mandatory in the U.S., so you’re hardly in hot water if you haven’t documented your COVID infection or lack thereof with the Centers for Disease Control and Prevention (CDC) or state or local public health authorities. Though perhaps more people would self-report if it were a requirement, says Dr. Sujata Ambardar, an infectious disease specialist at Inova Fairfax Hospital in Falls Church, Va.
“People probably are not self-reporting because they don’t want to have to not go to work—or they may want to go to work—it’s different reasons, and they may not want other people to know,” Ambardar tells Fortune. “Human nature is that they’ll probably only do it if they have to do it. Once you make it non-mandatory, then they tend not to do it.”
Today, if you get an antigen or PCR COVID test in a clinical setting, it’s still your health care provider’s job to report your results. While you’re well within your rights not to report your home test results, not doing so can come as a detriment to public health.
Between Feb. 1, 2022, and Jan. 1, 2023, an estimated 54 million adult COVID cases were unaccounted for in official records, according to a national study published Sept. 30 in the journal JAMA Network Open. That’s more than twice as many as those documented. At the state level, unaccounted infections ranged from 59,000 in Wyoming to 6.3 million in California. Researchers cited the government-led mass distribution of at-home tests as a possible driver of the discrepancies.
Report COVID results at MakeMyTestCount.org In theory, Ambardar says, reporting your COVID test results is “just one extra step.” But when that second line appears on the test card, confirming the disease has hit your household, formally documenting the outcome may not be your first priority. Even if you’re negative, you were likely feeling poorly enough to take the test in the first place and may not feel up to self-reporting.
But if and when you choose to do so, visit MakeMyTestCount.org to securely and anonymously report both positive and negative COVID test results. The site is a collaboration between medical data firm Care Evolution and the National Institute of Biomedical Imaging and Bioengineering, part of the National Institutes of Health.
MakeMyTestCount.org is free to use and doesn’t require you to immediately self-report. In fact, your results don’t even have to be recent. As of early October, the site allowed for the input of home test results going back to November 2021. If you need proof of illness for work or school, the site provides documentation. And while over-the-counter tests that screen for both COVID and flu aren’t as common as those that screen for COVID alone, you can report those results on the site, too.
Keep in mind that it’s just as important to report negative results as positive ones. The week ended Sept. 21, national COVID test positivity was 11.6%, CDC records show, down from 13.4% the previous week. If not for the inclusion of negative results, test positivity would always be 100%.
Depending on the brand of COVID test you’re using, you may not have to visit MakeMyTestCount.org at all. Some brands, such as iHealth, offer a free corresponding smartphone app. With the tap of your finger, you can forward your results to the CDC and/or your health care provider. If you have the time, notifying your doctor can help guide the course of COVID treatment in your community, says Dr. Donald Dumford, an infectious disease specialist at Cleveland Clinic Akron General.
“The more we know about the true number of cases of COVID, the better we’re able to understand the transmission of COVID at this point in time, as we go from it being pandemic to endemic, which means it’s just something we live with now,” Dumford tells Fortune. “It also helps us to identify the potential rise of new strains of infection, especially if you’re seeing a strong uptick in cases.”
Study Link: jamanetwork.com/journals/jamanetworkopen/fullarticle/2824211
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beardeddetectivepaper · 3 months ago
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The healthcare needs for the people of Tigray are wide-ranging and overwhelming. Beyond life-saving medication and medical equipment, the people of Tigray need access to nutrition, clean water, vaccines, and personal protective equipment (PPE) to fight against infectious diseases such as TB and the COVID-19 pandemic. Through the concerted efforts of donors and medical professionals HPN4Tigray is working to support unmet critical needs. We are currently spearheading projects in the region: providing life-saving medication such as insulin, malnutrition prevention programs for children under 5 who are currently Internally Displaced (IDP) populations, and clean water initiatives to prevent the breakout of cholera and other waterborne diseases. The vision of HPN4Tigray stretches beyond the current crisis and aims to continue partnering with medical institutions and NGOs on the ground to rehabilitate and rebuild communities. As individuals and health professionals we have an obligation to act during this dire humanitarian crisis and work to alleviate the suffering of future generations.
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rathockey · 4 months ago
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Have some COVID resources!! I recently started looking into the current state of COVID when I saw that cases were surging again and realized I was pretty uninformed about the current state of things, so I figure other people might be too.
So I‘m linking a few resources I‘ve bookmarked that has some good info about COVID and how to protect yourself and others.
Few things that stuck out to me:
1. We should all be masking at the very least indoors and in crowded outdoor settings (like concerts/festivals/etc)! PLEASE please mask if you are able to. N95/KN95 if you can! Surgical masks and cloth masks are better than nothing, but really try to get the respirator masks. You can reuse them as long as they don‘t get wet or crumpled.
2. The vaccine helps with severity but is actually not that great at preventing infection. Another good reason to be masking up - reducing the viral load you get exposed to helps the vaccine out.
3. Advocate for air purifiers in indoor spaces. We should be breathing clean air!
4. All COVID infections are severe or should be treated as such- ‚mild‘ cases included. Any infection is going to do damage to your body, and repeated infections increase your risk of Long COVID.
5. If you get COVID and you are able to, REST! Mind and body. This will go a long way to preventing long COVID. I know not everyone is in a position that they can do this, but take whatever time you can and let your body rest and heal.
And here are the resources I‘ve found:
This has a great PDF with a lot of good info and sources for all of it, as well as a small zine version you can hand out - https://linktr.ee/act_up_mask_up
This is a map with wastewater data, so you can see how things are trending nationwide (US only sorry!) and in various regions. Check and see if your state or city has its own tracker as well - I know Chicago does.
And here is a site that provides information to some questions/statements people say in attempts to get people to „move past“ COVID. This also has a lot of good information about the current state of COVID.
In conclusion (because this is a middle school paper now i guess)
MASK!
Get the boosters! There are new vaccines being developed that will hopefully help us stay ahead of these variants that keep evolving, but the best way to help those are to mask! Less infections mean less variants :)
AND ADVOCATE FOR BETTER COVID PROTECTIONS AND PROTOCOLS!!! We can only do so much as individuals, we have to lobby for governmental and systemic changes.
Also pls reblog this (and feel free to add your own resources! especially if you have resources for non-usamericans, mine are all pretty US focused unfortunately)
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its-zaina · 10 months ago
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One hundred days of the Israeli aggression on the Gaza Strip.
(100) days since the war of genocide and ethnic cleansing waged by the “Israeli” occupation army against our defenseless Palestinian people and against civilians, children and women, during which 2000 massacres were committed.
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(100) days into the war of genocide, during which we lost (31,000) martyrs and missing persons, of whom (23,968) martyrs arrived in hospitals, including (10,600) martyrs of children, (7,200) martyrs of women, and (337) martyrs of medical staff. (45) martyrs from civil defense, and (117) martyrs from journalists.
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(100) days into the genocide war, and (7,000) are still missing under the rubble. Medical teams have not been able to recover them yet as a result of the continuous bombing and the lack of fuel, 70% of whom are children and women.
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(100) days after the war of genocide, the number of wounded reached (60,582) wounded, deprived of travel for treatment in Arab and non-Arab hospitals due to the closure of the Rafah crossing in front of them and in front of more than (10,000) cancer patients who face the risk of death without anyone looking at them.
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(100) days after the war of extermination, (2) million Palestinian citizens were displaced in the governorates of the Gaza Strip. They live a very tragic life. They do not find food, water, or medicine, and (400,000) of them became infected with infectious diseases as a result of displacement and its unforeseen conditions.
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CEASE_FIRE_IN_GAZA_NOW.
SAVE_THE_CHILDREN_OF_GAZA.
END_THE_ISRAELI_OCCUPATION.
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homeofhousechickens · 3 months ago
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Hii, I saw your Marek's disease post, my cousin has a hen that has this kind of eye but she's ok, she eats, moves and everything, do you maybe know if this type can also evolve and become the most dangerous types like the paralysis? I'll be glad if you can answer and hope you have a great day
There are 5 different "forms" of Mareks and different "strains" of the virus that are more lethal or infectious then others. It's possible for a bird to present with multiple symptoms and forms when they have the disease.
Nerve form- Birds with this form have tumors infiltrate into their peripheral nerves. This causes symptoms like wry neck and sometimes a head tilt. It can also cause a chicken to have a slow crop and have trouble emptying. 20% of birds with this form die
Transient paralysis form - Causes brain edema and ataxia. The bird can have partial paralysis of the neck and legs. Usually, you will see these birds trying to use their wings to get around while falling over a bunch. 30% of birds with this form will die.
Ocular form- The virus replicates in the eye, causing tumors and vision loss. This causes the shape and color of the eye to change. 25% of birds with this form will die.
Skin form- The virus replicates in the skin causing tumor growth and enlarged feather follicles. Usually the location for these is around the head, legs, and vent. The bird will be lumpy and might have wonky feather growth but that's usually it. This form has the lowest mortality rate.
Visceral form- Tumors develop all throughout the body and onto the internal organs. The symptoms will present differently depending on what organs and systems are affected. 60-80% of birds with this form will die.
For chickens with Ocular Mareks they are usually older birds that have a bit of an immunity to the virus which is why their body is able to kind of suppress it but unfortunately the chicken can still have tumor development elsewhere in her body especially if her immune system gets compromised by a different illness like coccidosis or fowl pox.
If your girl has the Ocular form you must assume the rest of your flock has it and it's possible for it to present as the other forms. Mareks can stay dormant in a host for a long time then pop out when the birds immune system is weakened.
For anyone reading this and getting worried..
YOU CAN TEST FOR MAREKS! A lot of people don't know you can test living birds for the disease but it can also be diagnosed via necropsy. Your vet can help you with the testing but you can also do the testing yourself using something like VetDNA.com.
To avoid Mareks you can get your birds vaccinated and only purchase from NPIP certified flocks. The vaccine won't stop the spread of the disease but it can prevent birds from showing symptoms. If you have a mareks positive flock it's important to keep them on your property and dont sell them or show them as they can infect other birds.
Good biosecurity practices are a must and the best way to prevent an outbreak is running a closed flock. No adult or baby birds are added everything is hatched and raised on the property is the ideal. Of course accidents can still happen like if you have a close neighbor with an infected flock. Mareks spreads through the dander so it's important that infected birds don't share air space with non infected birds.
If your birds do have Mareks and you want a flock that isn't infected the best thing to do is either cull your current flock, or wait for them to pass naturally. There are certain cleaners like Rescue and Kennelsol that kill the Mareks virus so you would want to clean all old feeders and waterer with it (or get new ones) and I have seen people say to burn down the old coop as it can be tricky removing the dust from the crevices. Mareks can live in the soil for a long long time but like other viruses you can still work towards sanitizing and decomtaminating the soil.
You can still hatch eggs from Mareks infected birds as the disease doesn't transfer vertically.
Hopefully this is the information you were looking for
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gutsfics · 6 months ago
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AH, PB'S UNDER RESEARCH OF A TOPIC THEY ARE WRITING ABOUT MY FUCKING BELOATHED
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Um. does yellow fever have a different context than what i know it to be?
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bestiarium · 4 months ago
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On the origin of vampires: Petar Blagojević [Serbian folktales]
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Vampires, and their many variations, are some of the most popular monsters in modern fiction. Though their powers and abilities vary between authors and traditions, they are almost always characterized by a powerful urge to drink the blood of the living.
Tracking down the origin of the vampire myth is pretty difficult, as many many variations of blood-sucking undead creatures have appeared throughout folktales, popular literature and mythologies from around the globe, and recounting their history would take way too much time for this article. But it’s safe to say that some particular vampires played a bigger role than others in shaping the modern idea of what exactly constitutes a ‘vampire’. No discussion about the origin of vampires would be complete without mentioning Bram Stoker’s ever popular novel Dracula, for instance: it pretty much defined the current popular image of a vampire. But vampires go back further than that:
In 1725, a Serbian village (most likely the current Kisiljevo) was supposedly haunted by a living corpse who drank the blood of innocent villagers. This was not the first appearance of a blood-drinking undead creature in folklore or fiction, but it was a pretty influential one, being one of the first cases of a ‘vampire’ to reach headlines and become famous.
Provisor Frombald, an official responsible for the Habsburg military frontier, wrote a report about the incident: 9 people had died from unclear causes in the span of only 2 days, meaning an investigation was in order. What’s more, the deceased had claimed before their deaths that they were all recently visited by a local man named Petar Blagojević, who had entered their homes at night and strangled them. Petar had passed away 3 months before the incident, so clearly this was impossible.
His widow claimed that Petar had recently visited her, still alive, to collect his shoes. The villagers, not needing further convincing, called for the grave to be dug up so that the corpse could be examined. What they found was a non-decomposed body, with hair and nails that had seemingly continued to grow after his death. Fresh blood (or so it was claimed) flowed from Petar’s mouth.
In a kind of ‘posthumous execution’, the body was impaled through the heart and then cremated.
The story was revisited in 1728 by Michael Ranft, who proposed that Petar had died from some infectious illness that was then contracted by several people who, for one reason or another, came into contact with the corpse. Or perhaps the disease was already present in the village and Petar was merely the first to succumb to it, and was then used as a scapegoat to put the blame on.
Sources: Bohn, T. M., 2019, The Vampire: Origins of a European Myth, Berghahn Books, p. 78-80, 304 pp. Charney, N. and Slapak, S., 2023, The Slavic Myths, Thames & Hudson, 240 pp. (image source: Dusan Pavlic)
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