#nephroprotective effect

[tomasorban]

Put a half-teaspoon in each drink, soup, meal... (and 3-5 grams for acute pain)

The beneficial effects of turmeric are traditionally achieved through dietary consumption, even at low levels, over long periods of time. The activities of turmeric include antibacterial, antiviral, anti-inflammatory, antitumor, antioxidant, antiseptic, cardioprotective, hepatoprotective, nephroprotective, radioprotective, and digestive activities. Phytochemical analysis of turmeric has revealed a large number of compounds, including curcumin, volatile oil, and curcuminoids, which have been found to have potent pharmacological properties.

Turmeric is used as an herbal medicine for rheumatoid arthritis, chronic anterior uveitis, conjunctivitis, skin cancer, small pox, chicken pox, wound healing, urinary tract infections, and liver ailments (Dixit, Jain, and Joshi 1988). It is also used for digestive disorders; to reduce flatus, jaundice, menstrual difficulties, and colic; for abdominal pain and distension (Bundy et al. 2004); and for dyspeptic conditions including loss of appetite, postprandial feelings of fullness, and liver and gallbladder complaints. It has anti-inflammatory, choleretic, antimicrobial, and carminative actions (Mills and Bone 2000). The main clinical targets of turmeric are the digestive organs: in the intestine, for treatment of diseases such as familial adenomatous polyposis (Cruz-Correa et al. 2006); in the bowels, for treatment of inflammatory bowel disease (Hanai and Sugimoto 2009); and in the colon, for treatment of colon cancer (Naganuma et al. 2006). For arthritis, dosages of 8–60 g of fresh turmeric root three times daily have been recommended (Fetrow and Avila 1999). For dyspepsia, 1.3–3.0 g of turmeric root is recommended.

full artice: https://www.ncbi.nlm.nih.gov/books/NBK92752/

[raj-kanvar-5435]

The Incredible Health Benefits of Edible and Wild Mushrooms

Introduction

Throughout history, mushrooms have been an essential part of diets worldwide due to their rich nutritional profile. This blog post delves into the multifaceted therapeutic and biological effects of both edible and wild mushrooms, highlighting their role not just as food but also as powerful functional foods in medicine.

Nutritional and Therapeutic Properties

Mushrooms are a powerhouse of essential nutrients, packed with phytonutrients like polysaccharides and dietary fibers, along with micronutrients and essential amino acids, the building blocks of proteins. Their broad spectrum of pharmacological properties includes antidiabetic, antioxidative, antiviral, antibacterial, osteoprotective, nephroprotective, and hepatoprotective effects. These properties make mushrooms incredibly beneficial for health, aiding in the healing and repair of various human organs and cells.

Medicinal Uses of Mushrooms

Both wild and medicinal mushrooms have demonstrated strong therapeutic and biological activities through in vivo and in vitro assays. Their extracts exhibit multifunctional activities, which are crucial in the development of nutraceuticals and pharmaceuticals. This extensive use of mushrooms in medicine underscores their potential as a sustainable source of therapeutic agents.

Future Prospects and Challenges

The review also discusses the future outlook of mushrooms as functional foods, including the challenges associated with their cultivation and processing. It emphasizes the need for further research to exploit mushrooms' full potential, particularly in the realms of nutraceutical and pharmaceutical production.

Conclusion

Mushrooms are not only a versatile and nutritious addition to our diet but also exhibit significant medicinal properties that can be harnessed for health improvements. Their wide range of beneficial compounds positions them as a key component of the food and pharmaceutical industries, promising exciting developments in natural health solutions.

References and Further Reading

Medicinal Mushrooms: Bioactive Compounds, Use, and Clinical Trials

Bioactive Phytochemical Constituents of Wild Edible Mushrooms from Southeast Asia

Frequently Asked Questions (FAQs) 

Q1: What are the main health benefits of consuming mushrooms?

A1: Mushrooms offer a range of health benefits including anti-inflammatory, antioxidant, and immune-boosting properties. They are rich in dietary fibers, essential amino acids, and phytonutrients that contribute to better health outcomes such as improved digestion, reduced risk of chronic diseases, and enhanced overall immunity.

Q2: Can mushrooms really help prevent or treat diseases?

A2: Yes, mushrooms have been shown to possess various pharmacological properties such as antidiabetic, antioxidative, antiviral, and antibacterial activities. They are also used in preventing and managing conditions like diabetes, cancer, and heart diseases due to their therapeutic compounds.

Q3: Are wild mushrooms better than cultivated ones?

A3: Both wild and cultivated mushrooms have unique benefits. Wild mushrooms often contain higher levels of certain nutrients and bioactive compounds due to their natural growth environments. However, cultivated mushrooms provide consistency in quality and availability, and are free from contaminants often found in wild varieties.

Q4: How can mushrooms be incorporated into the diet?

A4: Mushrooms are extremely versatile and can be included in the diet in various ways. They can be used fresh, dried, or powdered in soups, salads, stir-fries, and as meat substitutes in vegetarian and vegan dishes.

Q5: Are there any risks associated with consuming mushrooms?

A5: While mushrooms are generally safe for most people, some individuals may have allergies or sensitivities. Additionally, certain wild mushrooms are toxic and should not be consumed unless properly identified as safe. It is always recommended to source mushrooms from reliable suppliers or gather them with an expert's guidance.

[jppres]

N-acetylglucosamine increases the efficacy of quercetin in the treatment of experimental acute kidney injury

N-acetylglucosamine increases the efficacy of quercetin in the treatment of experimental acute kidney injury. @JPPRes

Article published in Journal of Pharmacy & Pharmacognosy Research 8(1): 53-63, 2020. Sergii K. Shebeko*, Igor A. Zupanets, Viktoriia V. Propisnova

Department of Clinical Pharmacology and Clinical Pharmacy, National University of Pharmacy, Pushkinskaya str., 27, Kharkiv, 61057, Ukraine.*E-mail: clinpharm@nuph.edu.ua

Abstract

Context: Acute kidney injury (AKI) is a common…

[topdoctor41-blog]

Dates - The Healthiest Fruit On This Earth.

The Health Benefits of Dates Fruits

Dates are an extremely versatile fruit that give the health benefits of dates fruits to your diet regimen. Dates date back to the times of the Egyptians as well as the Romans.

Dates are belonging to Southern Africa, Yemen, Egypt, Iran, Central Asia, South Africa, South The United States, and also Asia. They were actually planted as early as 3500 B.C. However dates simply became prominent in the West along with the invention of the fruit through Greeks, that utilized them for their famous connoisseur dish "Hellenic cooking". The fruit's appeal likewise grew when Europeans brought all of them back to Europe.

Dates involved Spain and after that were brought back to Europe. It was actually brought to England and also eventually to the USA. It was actually only in the 1700s that Americans started taking in the fruit for its healthy health buildings.

Dates are actually sizable and challenging fruits, therefore they are suitable for packaging. Dates can be consumed raw, as well as most especially when they are actually cut in brief or medium-sized items, so they keep all the health benefits of dates. Dates could be consumed dried out, prepared, or perhaps frozen.

Dates are rich in potassium, fiber, and also vitamins. They can be made use of as a substitute for glucose. The good thing regarding dates is that you can consume them with almost just about anything. It matters not what kind of food you are actually going to put the dates on.

Dates are rich in minerals and antioxidants. They can assist you reduce weight due to the fact that they can hinder the absorption of body fat in the physical body. Even the heart is capable of absorbing the nutrients that are consisted of in dates. Dates also have monounsaturated excess fats, which are understood to lower cholesterol amounts.

See to it you eat dates on a regular basis. To take pleasure in the health benefits of dates you ought to regularly take one fifty percent of a date as aspect of your diet. If you want to take pleasure in the various other benefits of dates, you may take one date along with some natural yogurt, natural honey, or even oat meal.

Dates are an excellent resource of fiber that may be made use of to prevent irregular bowel movements. The thread will create your feces softer, therefore you can easily pass it easily.

Dates are actually a really good source of potassium that can easily likewise aid in handling high blood pressure. They are also abundant in the crucial mineral calcium. Calcium mineral aids in creating bone tissue and also stopping bone tissue health conditions.

Dates are additionally wealthy in vitamin C that can easily help you battle skin disease as well as additionally skin cancer cells. https://www.greendiamond.co/tag/nephroprotective-and-anti-cancer/ may eat dates, which may be eaten dry or even in their clean kind, as well as they can easily assist defend your eyes.

Dates are actually rich in vitamin E that can aid you fight against cost-free radicals that can easily trigger cancer cells. They are actually also excellent resource of magnesium mineral that may assist you kick back. Magnesium is additionally really good in harmonizing the blood sugar amount.

Dates are also an excellent source of carbohydrate that can be made use of alternatively for flour. Carbohydrate will certainly permit you to eat less calories as well as consequently you may drop weight.

Dates Eaten Together With Fruits - Is it Even More Healthy Than Dates Alone?

Individuals of various ages, that really love to consume new fruits as well as additionally dates alongside other nourishing foods. As the benefits of fruits are actually incredible, there are so many folks around who really love to consume fruits as well as dates as their preferred.

A variety of folks ponder if dates are actually eaten alongside fruits are actually much more healthy than dates eaten alone. The response is actually a huge of course, however the honest truth is dates without fruits are not more nutritious than dates along with fruits.

Date and dates are actually consumed alone are even more rich in excess fats and also calories than when they are actually combined with fruits. The high-fat content that appears in dates alone may be a trouble for the body. The greatest technique to avoid this trouble is actually to possess dates as a principal element in your diet regimen.

Dates are actually a great source of fibre, thus date is a superb breakfast possibility. The thread in dates may lower the threat of digestive tract cancer cells. Dates additionally possess the highest concentration of thread, contrasted to some other meals accessible on the market.

The majority of people think about if dates are actually eaten together with fruits are actually even more healthy than dates eaten alone. The answer is actually a big of course, but the reality is dates without fruits are actually not extra healthy than dates along with fruits.

Date and dates are eaten along with fruits have a lot of benefits. Due to the fact that dates are high in fiber, they can stop constipation and hence, the danger of bowel cancer cells is reduced. The high concentrations of thread in dates can be good for our digestive unit.

Dates consumed along with fruits are actually even more nourishing than dates alone. The higher attentions of nutrients in dates, assist you absorb your meals a lot faster than normal. These chemicals as well as vitamins may assist enhance the health of your bones and prevent you from building brittle bones.

Dates and also dates eaten along with fruits are not even more healthy than dates consumed alone. The most effective factor is actually that you will certainly acquire the wanted benefits without the negative aspects of eating fruits and also dates as a snack, just pick the right mixture.

Dried out Dates

The growing of dates has been actually going with 1000s of years. Though dates can be consumed clean, plain dates are popular. Amongst the kinds of dates, Deglet Noor and also Medjool are actually very popular for their excellent revel in. They are actually referred to as the master of dates for their fineness for their honey flavored flavor.

Folks frequently love their organization, chewy candy type. Consuming dates as a snack food or even using it as a taste enhancer boost the nutritional value of the meals. They are typically used in the recipe for prepping breadstuff and also treats.

The getting of dried out dates, can possess some cooking effect you intend to get out of it. Dry dates are versatile to become a component of your early morning healthy smoothie, packed to serve as an impressive offering for the attendees and also for you. For the incorporated sweetness, dry out dates could be combined into pork and chick dishes.

You might be buying dates in bigger amount once you discover the assorted health benefits they supply. Keeping match as well as powerful ought to be a way of living top priority. Preventing disease is an important factor in residing a complete as well as dynamic life. The incorporation of healthy meals into your diets may have substantial health benefits. It functions as a defensive element versus plenty of health condition. It is just one of the greatest measures that you can easily consider staying a healthy diet.

Extra is actually that the Dry dates assist digestive function, and also always keep the soul and also human brain in the right purchase. They maintain colon, prostate, breast, bronchi, as well as pancreatic versus any cancerous assault. Dates can easily help reducing blood pressure, soothe irregularity, stop diarrhea, and anemia develops away from iron shortages. The dates may be a perk for expectant females or even an individual suffering from joint inflammation as well as taking a weight management diet.

The method of collecting of the dates involves placing a web around the fruit that has developed in hairs in a big number of the tree branches. Dates that fall on the ground aren't utilized for extreme bruising as well as possible putridity. Dates that are expanded in significant quantities are actually moved for handling and also made ready for covering as well as product packaging.

Meanwhile, if dates are collected in small number, the dates from the stem, are actually kept on a holder and kept under the drying process. This is among the methods that is actually taken on for transforming fresh dates right into completely dry dates successfully.

Need Our Service OrHave Queries ?

Address Green Diamond International S/B (1007167-M) No.14, Jln bpp 8/2, Bandar putra permai, 43300 Seri Kembangan, Selangor, Malaysia Contact Details 0060389399582 Green Diamond International S/B (1007167-M) No.14, Jln bpp 8/2, Bandar putra permai, 43300 Seri Kembangan, Selangor, Malaysia Monday 10:00-20:00 Tuesday 10:00-20:00 Wednesday 10:00-20:00 Thursday 10:00-20:00 Friday 10:00-20:00 Saturday 10:00-20:00 Sunday Closed

[physiqueenlightenment]

Detox… The Removal Of Toxic-Substances From The Body

Naked Nutrient ~ Powdered Mushroom Blends

Visit ~ https://nakednutrient.com/collections/frontpage/products/organic-mushroom-powder-extract-supplement

Today the investigations proceed to advise that the Toxins and Chemicals that we are all exposed to do in fact influence our health.

This includes Dietary and Environmental Factors.

Some chemicals are capable of Endocrine or, Hormonal disruption; others affect Neurotransmitters; the modified Amino-Acids used as communication between Neurons.

While certain chemicals can impair our Immune System Functions, while also, prompting Gastrointestinal Sensitivities or Digestive discomfort.

Over the past few decades or so, the concept of Detoxing has become a much more potent declaration.

In the United States alone, we are confronted with what has been said to be, over 80,000 different Chemicals; a foretold 4 billion pounds of Chemical-Pollutants emerging from our Plastic Containers, Pesticides, Solvents, and Heavy-Metals.

All of which intrude into our Environment; finding access to the Atmosphere, Soils, and so, to our Foods, and Water-Supply; in addition, Fire-Retardant Fabric\Clothing, Furniture.  

Ultimately, all finding the Passage to our Body.

The Human Body is capable of Cleansing itself of these Damaging-Chemicals.

However… The absolute volume of what we are presently exposed too can overburden our Natural Detoxification processes and allow those Toxins to accumulate in our Tissues.

Toxic Substances are everywhere…  

The Body is not only exposed to Toxic Chemicals in the Environment; Toxins are also produced in the Body through Natural Chemical Reactions.

Research into Human-Biotransformation and Elimination-Systems continues to emerge, in this modern day.

With several clinical Studies engaging in evaluating the effects of Foods and the Food-Derived Components on the activity of our Detoxification Pathways.

Food-based nutrients have been continually investigated for their role in the Modulation of Metabolic Pathways involved in the Detoxification Processes.

From ancient times, Mushrooms have been admired by humankind as a culinary wonder; as well as a community Medicine in the Oriental Custom.

However, within these modernized days, there has been an observed and powerful interest with the American investigations into the Pharmaceutical Potential of the Medicinal Mushrooms.

Reishi Mushroom … A well-known Traditional Medicinal Mushroom that has been shown to have prominent…

Liver-Protective\Cleansing abilities…   Boosts Immune System Functions... Cleansing conclusions in Kidney Disease… Anti-Toxin effects in Liver Disease… Anti-Carcinogen Capabilities…

The Turkey Tail Mushroom …

Stimulates\Modulate Immune Functions… Reduces Inflammation, so Pain Chemotherapy Aid\Detoxification…   Cancer Management...

The Shiitake Mushroom…

Boosts Immune Functions… Lowers Cholesterol Levels… Diabetes Management… Lowers High Blood Pressure…

The Maitake Mushroom…

Chemotherapy Aid\Detoxification…   Stimulates Immune Functions…

Cordyceps Mushroom…

Aids and so Cleanses in Kidney Disorders… Anti Toxin effects aiding the Liver Cleansing Functions…

Lion's Mane Mushroom…

Cardioprotective… Neuro-Protective…

Oyster Mushroom…

Stimulation of Immune Phagocytic Cell Functions… Reduces Atherosclerosis…

Phellinus Linteus Mushroom & Benefits…

Antioxidant Properties… Potential Anti-Cancer… Anti-Bacterial…

A total of 126 Medicinal Functions are thought to be produced by the  Medicinal Mushrooms; including antitumor, immunomodulating, antioxidant, radical scavenging…

I should say here as well that, special attention is paid to the  Mushroom Polysaccharides. Beta-glucans…  the naturally occurring polysaccharides.

These glucose polymers are constituents of the cell wall of certain pathogenic bacteria and fungi. These substances have shown to increase the human Immune defense by activating the complement system…

The complement system is a part of our Immune System that enhances, or, complements the ability of the Antibodies and the Phagocytic Immune eating cells to clear microbes and damaged cellular debris…  

Enhancing the capture, aiding the Macrophages (immune eating cells) and the Natural Killer Cell functions.

The producing of these human cellular responses by these Mushroom Beta-glucans involves their interactions with several cell surface signaling receptors.

Mushrooms are also Environmentally friendly...

They Bio-synthesize their very own food from crop residues; which would otherwise cause health hazards for us.

The Medicinal uses of Mushrooms identified so far are… Anti-oxidant… Anti-diabetic… Hypocholesterolemic… Anti-Tumor… Anti-Cancer… Immunomodulatory… Anti-Allergen… Nephroprotective… Antimicrobial Agents...

There are many examples of Detoxifications including but not limited too… Alcohol Detoxification… Drug Detoxification… Metabolic Detoxification…

A regular intake of Mushrooms or the  Powdered Extract Blends for an Option having the same Nutrient Health Benefits; is believed by the investigating researchers to make us healthier, while diminishing the Toxic-Load, for the Longer Healthy Life.

These Therapeutic Medicinal Procedures are as simple as making your Daily-Cup of Coffee or Tea... https://youtu.be/0R9KPdKp9yE

Supplementary Nutritional Option…

https://nakednutrient.com/collections/frontpage/products/organic-mushroom-powder-extract-supplement

For Your Health & Wellness Educational Purposes Christine Foutch - Holistic Physician

[imrmarketresearch20]

Sodium Thiosulfate Pentahydrate Market

According to this latest study, the growth in the Sodium Thiosulfate Pentahydrate market will change significantly from the previous year. Over the next five years, Sodium Thiosulfate Pentahydrate will register a CAGR in terms of revenue, and the global market size will reach USD in millions by 2028.

Sodium thiosulfate pentahydrate is a hydrate consisting of sodium thiosulfate with 5 mol eq. of water. It has a role as an antidote to cyanide poisoning, a nephroprotective agent and an antifungal drug. It contains a sodium thiosulfate. Inhalation: May cause upper respiratory tract and mucous membrane irritation. Ingestion: Sodium Thiosulfate is an agent with a low order of toxicity. Ingestion of large doses may cause gastrointestinal irritation disturbances with nausea, vomiting, addominal cramping, diarrhea, metabolic acidosis, and hypernatremia. Sodium thiosulfate, also spelled sodium thiosulphate, is used as a medication to treat cyanide poisoning, pityriasis versicolor, and to decrease side effects from cisplatin. For cyanide poisoning it is often used after the medication sodium nitrite and typically only recommended for severe cases. It is either given by injection into a vein or applied to the skin.

[marketnewskk]

Sodium Thiosulphate Market

According to this latest study, the growth in the Sodium Thiosulfate Pentahydrate market will change significantly from the previous year. Over the next five years, Sodium Thiosulfate Pentahydrate will register a CAGR in terms of revenue, and the global market size will reach USD in millions by 2028.

Sodium thiosulfate pentahydrate is a hydrate consisting of sodium thiosulfate with 5 mol eq. of water. It has a role as an antidote to cyanide poisoning, a nephroprotective agent and an antifungal drug. It contains a sodium thiosulfate. Inhalation: May cause upper respiratory tract and mucous membrane irritation. Ingestion: Sodium Thiosulfate is an agent with a low order of toxicity. Ingestion of large doses may cause gastrointestinal irritation disturbances with nausea, vomiting, addominal cramping, diarrhea, metabolic acidosis, and hypernatremia. Sodium thiosulfate, also spelled sodium thiosulphate, is used as a medication to treat cyanide poisoning, pityriasis versicolor, and to decrease side effects from cisplatin. For cyanide poisoning it is often used after the medication sodium nitrite and typically only recommended for severe cases. It is either given by injection into a vein or applied to the skin.

[imrmarket]

Sodium Thiosulfate Pentahydrate Market  |Leading Top Companies, Types, Applications and Key players

According to this latest study, the growth in the Sodium Thiosulfate Pentahydrate market will change significantly from the previous year. Over the next five years, Sodium Thiosulfate Pentahydrate will register a CAGR in terms of revenue, and the global market size will reach USD in millions by 2028.

Sodium thiosulfate pentahydrate is a hydrate consisting of sodium thiosulfate with 5 mol eq. of water. It has a role as an antidote to cyanide poisoning, a nephroprotective agent and an antifungal drug. It contains a sodium thiosulfate. Inhalation: May cause upper respiratory tract and mucous membrane irritation. Ingestion: Sodium Thiosulfate is an agent with a low order of toxicity. Ingestion of large doses may cause gastrointestinal irritation disturbances with nausea, vomiting, addominal cramping, diarrhea, metabolic acidosis, and hypernatremia. Sodium thiosulfate, also spelled sodium thiosulphate, is used as a medication to treat cyanide poisoning, pityriasis versicolor, and to decrease side effects from cisplatin. For cyanide poisoning it is often used after the medication sodium nitrite and typically only recommended for severe cases. It is either given by injection into a vein or applied to the skin.

The report also tracks the latest market dynamics, such as driving factors, restraining factors, and industry news like mergers, acquisitions, and investments. Global Sodium Thiosulfate Pentahydrate Market Size (value and volume), market share, growth rate by types, applications, and combines both qualitative and quantitative methods to make micro and macro forecasts in different regions or countries.

The Global Sodium Thiosulfate Pentahydrate Market Trends, development and marketing channels are analyzed. Finally, the feasibility of new investment projects is assessed and overall research conclusions offered.

Top key players cited in the report:        

Spectrum Chemical Mfg.Corp, Anmol Chemicals, Cosmic Chemicals, Vishnupriya Chemicals Private Limited, FInOrIC, Muby Chemicals, Shakti Chemicals, Vishnupriya Chemicals Pvt. Ltd, Lakshmi Chemical Industries, Nakarai, Akash Purochem Private Limited, Ing. Petr Svec - PENTA, Chaitanya Chemicals

Market has segmented the Sodium Thiosulfate Pentahydrate market on the basis of type, application, and region:

By Type:

·         Purity

·         Purity >99%

By Application:

 ·         Photography

·         Textile

·         Pharmaceutical

·         Others

The report covers key regions of the global Sodium Thiosulfate Pentahydrate market. This list includes many regions such as:

·         North America (U.S., Canada, Mexico)

·         Europe (Germany, U.K., France, Italy, Russia, Spain, Rest of Europe)

·         Asia-Pacific (China, India, Japan, Southeast Asia, Rest of APAC)

·         Middle East & Africa (GCC Countries, South Africa, Rest of MEA)

·         South America (Brazil, Argentina, Rest of South America)

COVID-19 Impact Sodium Thiosulfate Pentahydrate market    

The COVID-19 pandemic has had devastating effects on several industry verticals globally. To constrain the number of cases and slow the coronavirus spread, various public health guidelines were implemented in different countries across the globe. COVID-19 protocols ranging from declaring national emergency states, enforcing stay-at-home orders, closing nonessential business operations and schools, banning public gatherings, imposing curfews, distributing digital passes, and allowing police to restrict citizen movements within a country, as well as closing international borders. With the growing vaccination rate, governments are uplifting the protocols to give a boost to the stagnant economy. Like other industries, Sodium Thiosulfate Pentahydrate Market have experienced slowdown the growth, however market is expected bounce back as restrictions are being lifted up by governments across the globe.

IMR offers a comprehensive overview of the market through the analysis of key parameters such as revenue, price, competition, and promotions, as well as the study, synthesis, and summarization of data from different sources. It analyzes the leading industry drivers and shows numerous market components. The information offered is thorough, dependable, and the result of a comprehensive primary and secondary study. IMR market research reports offer a comprehensive global market as well as an in-depth strategic sourcing methodology and analysis based on qualitative and quantitative research to anticipate market growth.

Reasons to Purchase this Report:

• Qualitative and quantitative analysis of the market based on segmentation involving both economic as well as non-economic factors

• Provision of market value (USD Billion) data for each segment and sub-segment

• Indicates the region and segment that is expected to witness the fastest growth as well as to dominate the market

• Analysis by geography highlighting the consumption of the product/service in the region as well as indicating the factors that are affecting the market within each region

• Competitive landscape which incorporates the market ranking of the major players, along with new service/product launches, partnerships, business expansions and acquisitions in the past five years of companies profiled

[agreenroad]

NAC found to protect kidneys against VENOM damage (no wonder FDA wants to ban it) – Dr. Eddy Bettermann MD

NAC found to protect kidneys against VENOM damage (no wonder FDA wants to ban it) – Dr. Eddy Bettermann MD

A 2014 study published in the journal Toxicon shows that N-acetyl-L-cysteine (NAC) is a powerful remedy against animal venom poisoning.Researchers from Instituto Butantan in Brazil studied the effects of NAC on mice injected with Bothrops jararaca (a highly venomous pit viper snake) and Crotalus durissus terrificus(tropical rattlesnake) venoms. Since NAC is a well-known nephroprotective…

[marketwire]

Sodium Thiosulphate Market Forecast to Reach $627 Million by 2026

Sodium Thiosulphate Market is forecast to reach $627 million by 2026, after growing at a CAGR of 4.5% during 2021-2026. Sodium thiosulphate is a colorless inorganic sodium salt that dissolves well in water composed of sodium and thiosulfate ions in a 2:1 ratio. It is used for the processing of photographic paper and photographic films. Sodium Thiosulphate liquid is used to de-chlorinate ballast waters prior to discharge to the environment. The surging use of sodium thiosulphate for the removal of heavy metals from industrial wastewater is expected to drive the growth of the sodium thiosulphate market size during forecast period. Furthermore, accelerating demand of sodium thiosulphate from healthcare sector for the formulation of antidotes used to treat cyanide poisoning also aids to the market growth.

Sodium Thiosulphate Market Segment Analysis - By Type

Sodium thiosulphate pentahydrate segment holds the largest share of more than 60% in the sodium thiosulphate market in 2020. Sodium thiosulfate pentahydrate is a hydrate consisting of sodium thiosulfate with 5 molar eq. of water. Sodium thiosulphate pentahydrate is used by photographers to fix developed negatives and prints. It acts by dissolving the part of the silver salts coated onto film which remain unchanged by exposure to light. Sodium thiosulphate pentahydrate is also used as an oxygen scavenging agent in steam boilers which may aid the growth of the market.

Request for Sample Report @ https://www.industryarc.com/pdfdownload.php?id=16255

Report Price: $ 4500 (Single User License)

Sodium Thiosulphate Market Segment Analysis - By Application

Medication segment holds the largest share of more than 25% in the sodium thiosulphate market in 2020. Sodium thiosulphate is used as an intravenous medication for metal poisoning. Sodium Thiosulphate acts as an antidote to cyanide poisoning, a nephroprotective agent and an antifungal drug. According to the American Association of Poison Control Centers Toxic Exposure Surveillance System, 2 of the 272 cyanide exposure cases in 2018 were fatal. Hence, fatality caused by cyanide poisoning coupled with increase in number of cases drive the growth of the sodium thiosulphate market. Furthermore, sodium thiosulphate also has potential for treating neurodegenerative diseases such as Alzheimer disease and Parkinson disease which in turn augment the market growth. Additionally, in the United States, the growing cases of chronic kidney diseases is expected to drive the market growth during the forecast period.

Sodium Thiosulphate Market Segment Analysis - By End-Use Industry

Based on the end-use industry, the water and wastewater treatment segment hold the largest share of more than 30% in the sodium thiosulphate market. Sodium thiosulphate neutralizes the chlorine, thus preventing further bactericidal effects on organisms in the water during transit. It also forms soluble complexes with certain heavy metals such as lead, mercury, arsenic, and cadmium facilitating their removal from industrial waste effluents. Heavy metals are known as carcinogens and may cause harm in lungs, liver, kidneys, and other vital organs. Therefore, surging health concerns and demand for freshwater fuels the growth of sodium thiosulphate market. According to the Organisation for Economic Co-operation and Development, freshwater demand is projected to increase by 55% globally between 2000 and 2050, significantly aiding the market growth.

Sodium Thiosulphate Market Segment Analysis - Geography

Asia Pacific holds the largest share of more than 45% in the sodium thiosulphate market in 2020 owing to developing industrial sector across the region leads to drive the demand for sodium thiosulphate. Sodium thiosulphate is used as an antichlor agent for the removal of chlorine from reaction vat in textile and pulp industries. Surging use of paper & pulp products as an alternative to single use plastics also aids the growth of the market in APAC region. According to the Japan Paper Association, the total paper and paperboard demand for domestic applications such as tissue paper, newsprint, and boxboard reached to 26,581 thousand metric tons in 2017 in Japan. Additionally, the Government of India provides financial assistance up to 50% of project cost for Common Effluent Treatment Plants (CETPs) subject to a ceiling of USD 11.5 million. The Indian Ministry of Textiles has implemented the Integrated Processing Development Scheme (IPDS) to enable the textile processing sector in meeting environmental standards. Thus, the growing investment and developing industrial sector across the region are fueling the growth of sodium thiosulphate in APAC region.

Sodium Thiosulphate Market Drivers

Increasing usage of sodium thiosulphate in food & beverages

Sodium Thiosulphate acts as a sequestrant that forms chelate complexes with polyvalent metal ions, especially copper, iron and nickel, and prevent the oxidation of the fats in the food. According to Flexible Packaging Association (FPA), Flexible Packaging is the second largest packaging segment in the U.S., garnering about 19 percent of the $170 billion U.S. packaging market as of June 2019 and largest market for flexible packaging is food (retail and institutional), accounting for about 59 percent of shipments. In addition, Food and Agriculture Organization’s (FAO) estimated that the demand for food will grow by 60% by 2050. Growing demand for packaged foods due to health concerns and changing lifestyle of the consumers is expected to drive the growth of the sodium thiosulphate market during the forecast period.

Growing demand from mining and oil industries

In the oil and gas industry, sodium thiosulphate is used to improve thermal stability of fluidized polymer suspensions. Energy Information Administration (EIA), estimated that the U.S. petroleum production in 2018 increased by 16% while production of natural gas rose by 12%, significantly proliferating the sodium thiosulphate market growth. Furthermore, investments and collaborations in petrochemical sector are expected to boost the market growth. For instance, in early 2017, the Danish government signed an agreement aimed at continuing oil production in the North Sea. As per the agreement, there will be a two-figure billion kroner investment in oil and gas extraction and the rebuilding of the Tyra field. This allows for the possibility to generate $3.9 billion by 2042. Additionally, Saudi Aramco and SABIC have also signed a memorandum of understanding to build a complex worth USD 20 billion to convert crude oil into chemicals in the country. Besides, Sodium Thiosulphate leaching is also used an alternative to cyanidation for the extraction of gold. According to United States Geological Survey, in 2017, domestic gold mine production was estimated to be about 245 tons, 10% more than that in 2016, and the value was estimated to be about $9.9 billion. Increase in mining activities and demand of gold for Jewellery and dentistry also boost the demand for sodium thiosulphate.

Download Sample Report @ https://www.industryarc.com/pdfdownload.php?id=16255

Sodium Thiosulphate Market Challenges

Efficacy and harmful effects of sodium thiosulphate

Sodium thiosulfate is a reducing agent. However, it scavenges less oxygen than sodium sulfite, sodium bisulfite or sodium metabisulfite. Prolong exposure to sodium thiosulphate may irritates skin, eye, nose, and throat. Sodium thiosulfate reacts slowly with chlorine under some conditions, and requires more time for dechlorination than most dechlorination chemicals. Over dechlorination with sodium thiosulfate may encourage thiobacillus and some other bacterial growth in water streams, particularly during low flow condition. In addition, presence of alternatives such as ammonium thiosulphate, Phenylarsine Oxide (PAO) solutions etc. which has better efficiency, restraints the market growth of sodium thiosulphate.

Emergence of COVID-19

The outbreak of COVID 19 has hampered the growth of sodium thiosulphate market. The supply chain disruption, price fluctuation of oil, and closure of manufacturing units due to coronavirus pandemic have lowered the demand globally. According to the Organization of the Petroleum Exporting Countries (OPEC), a 1.5 million barrel per day (mb/d) production cut for the second quarter of 2020, significantly lowering the demand for sodium thiosulphate. In addition, decrease in purchasing capital impacted the growth of textile, paper & pulp, and mining industries negatively affecting the growth of the sodium thiosulphate market.

Market Landscape

Technology launches, acquisitions and R&D activities are key strategies adopted by players in the sodium thiosulphate market report. In 2020, the market of sodium thiosulphate has been consolidated by the top 10 companies accounting for xx% of the share. Major players in the sodium thiosulphate market are NISSEI CORPORATION, Sankyo Kasei, Liyang Qingfeng Fine chemical Co. Ltd., Skyline Chemical Corporation, INEOS Group AG, Merck KGaA, Seidler Chemical Co, Inc., Wintersun Chemical, Hubbard-Hall, Veckridge Chemical Co Inc., Cater Chemicals Corporation, and Allan Chemical Corporation., among others.

Acquisitions/Technology Launches

In May 2017, Fennec Pharmaceuticals Inc. launched a Named Patient Programme (NPP) in Europe with a focus on the development of Sodium Thiosulfate (STS) for the prevention of platinum-induced ototoxicity in pediatric patients.

Key Takeaways

Rise in mining activities in the U.S also raises the demand for sodium thiosulphate. According to the U.S. Geological Survey, U.S. mines produced an estimated $82.2 billion of raw mineral materials in 2018, a 3 percent increase over the revised total of $79.7 billion in 2017.

Increasing environmental concerns and government restrictions augments the demand for sodium thiosulphate for water treatment and bleaching process.

Decline in manufacturing activities and disruption of supply chain due to the outbreak of coronavirus has hampered the growth of the sodium thiosulphate market.

Related Reports :

A. Photographic Chemicals Market

https://www.industryarc.com/Report/16088/photographic-chemicals-market.html

B. Sodium Acetate Market

https://www.industryarc.com/Report/17731/sodium-acetate-market.html

For more Chemicals and Materials Market reports, Please click here

About IndustryARC: IndustryARC primarily focuses on Cutting Edge Technologies and Newer Applications market research. Our Custom Research Services are designed to provide insights on the constant flux in the global supply-demand gap of markets. Our strong team of analysts enables us to meet the client research needs at a rapid speed, with a variety of options for your business. Any other custom requirements can be discussed with our team, drop an e-mail to sales@industryarc.com to discuss more about our consulting services.

[geohoneyseo]

Acacia Honey

Acacia honey is a pale, liquid glass-like honey produced by bees that feed on Acacia flowers. It contains vitamins A, C, and E, flavonoids, and essential fatty and amino acids. Acacia honey has hepatoprotective (liver) and nephroprotective kidney effects. This honey variant possesses anti-inflammatory - acacia honey.

[mbimphblog]

ANTICANCER ACTIVITY OF Pedalium murex Linn METHANOLIC LEAVES EXTRACT AGAINST A549 HUMAN LUNG CANCER CELL LINE |  Asian Journal of Advances in Research

Pedalium murex (Pedaliaceae), often known as Large Caltrops, is well-known for its pharmacological applications in traditional medicine. It is said to have good therapeutic characteristics that aid in the treatment of reproductive diseases in both men and women, including impotency, nocturnal discharges, gonorrhoea, and leucorrhoea. It also comprises a treatment for urinary and gastrointestinal tract problems. Antiulcerogenic, nephroprotective, hypolipidemic, sexual enhancer, mitigating, antidermatophytic, cancer prevention agent, antibacterial, and insecticidal activities have all been investigated pharmacologically. The current review may be a compilation of information gleaned from published research papers that focuses on the phytochemical and pharmacological features of P. murex. The high concentrations of methnolic extract will be useful in producing new formulations with therapeutic and cost-effective value in the future. A549 cells were treated with Pedalium murex leaves methanolic extract for six hours, twelve hours, twenty-four hours, and thirty-six hours, and their growth was controlled after 36 hours. Please see the link :- http://mbimph.com/index.php/AJOAIR/article/view/1646

[biomedres]

Journals on Cancer Medicine - BJSTR Journal

Study the Nephroprotective Effect of Ziziphus jujube Extract Against Cisplatin -Induced Nephrotoxicity by Faisal Mohammed Al Tenaiji* in Biomedical Journal of Scientific & Technical Research https://biomedres.us/fulltexts/BJSTR.MS.ID.002413.php Nephrotoxicity is a common adverse effect of many chemotherapeutic agents characterized by altered intraglomerular hemodynamics, tubular cell toxicity, inflammation, and thrombotic microangiopathy. Chemotherapy-induced tubular toxicity might be due to decreasing of mitochondrial function, interfering with tubular transport, increasing oxidative stress, and formation of free radicals. Cisplatin is an anticancer agent used largely in treatment of solid tumors. The mainstay dose-limiting toxicity of cisplatin is nephrotoxicity. In this study, we aimed to investigate the protective effects of Ziziphus jujube (ZE), a species of Ziziphus (L) in the buckthorn family Rhamnaceae, on cisplatin-induced nephrotoxicity. Twenty Sprague-Dawely rats were divided into four groups and received different drug combinations orally. Group I was regarded as control group and received normal saline. Group II received cisplatin at 5mg/kg, group III received ZE at 500mg/kg, and group IV received both cisplatin and ZE. All animals were decapitated 6 days after cisplatin administration. Results revealed that cisplatin induced nephrotoxicity as indicated by a significant increase in plasma creatinine and lipid peroxidation. This increase was significantly inhibited in animals pretreated with ZE. Histopathological observations were in correlation with the biochemical parameters in that ZE minimized cisplatin-induced renal tubular damage. Accordingly, ZE provides protection against cisplatin-induced nephrotoxicity in terms of oxidative stress. Cancer is a group of diseases in which cells in the body divide abnormally. The cancerous cells may occur in liquids, as in leukemia or can invade surrounding tissues and spread through the blood and lymph system and establish colonies to other parts of the body. When these cells have migrated to other regions in the body, the cancer is called disseminated or metastasized [1], there are various types of cancer depend on its location, such as lung, colon, breast, skin, ovarian or prostate cancer [2]. Localized cancers can be removed by surgery or irradiation with high survival rates. But, the success of these treatments is frequently limited by metastasis of cancer cells to distant body. For more articles on Journals on Cancer Medicine please click here bjstr Follow on Twitter : https://twitter.com/Biomedres01 Follow on Blogger : https://biomedres01.blogspot.com/ Like Our Pins On : https://www.pinterest.com/biomedres/   

[biomedgrid]

Biomed Grid | The Use of Ambrosia Moritima Methanolic Extract as Nephroprotective against Rifampin Induced Nephrotoxicity in Rats

Introduction

Plants are the most important source for traditional medicines and may contribute to the development of new medicines for various human health problems. Medicinal plants have played an essential role in the development of human culture, religions and ceremonies. 80% of the world’s inhabitants rely mainly on traditional medicines for their primary health care [1]. Medicinal plants are most important to daily health and practices particularly in developing countries, also herbal medicine became a topic of augmented global importance having impacted on both world health and International trade [2]. Drugs are sometimes associated with side effects, whereas phytochemical (plant extract) have been found to have fewer side effects, better patient tolerance, relatively less expenses and a long history of use and renewability in nature .The kidneys are a pair of organs located in the back of the abdomen. Each kidney is about 4 or 5 inches long about the size of fist. The kidneys’ functions are to filter the blood. All the blood in our bodies passes through the kidneys several times a day. The kidneys remove wastes, control the body’s fluid balance, and regulate the balance of electrolytes [3]. Nephrotoxicity is poisonous effect of some substances, both toxic chemicals and medication on the kidneys. Many of the drugs causes toxicity to the kidney, these drugs used in chemotherapy such as Cisplatin, Carboplatin.

Varieties of natural products, medicinal plants and dietary components have been evaluated as nephroprotective agents. Currently, medicinal plants are widely used in the treatment of many diseases owing their safety, cheapness and nontoxicity when compared with the synthetic drugs [4]. Increasing health concerns necessitate reliance on alternate remedies for sustaining good health. Medicinal plants are extensively used for the management and treatment of various diseases. Plant drugs are considered nontoxic and devoid of side effects [5].

Plant Material

Ambrosia moritima leaves belong to the family of Asteraceae were collected in May 2017 from Alkhartoum city. The plant was authenticated by the botanists in medicinal and aromatic plants research institute

Preparation of extract

500 g of Ambrosia moritima was successively extracted by soaking in 80% methanol for about seventy-two hours of solvent with daily filtration and evaporation. Solvents were evaporated under reduced pressure to dryness using rotary evaporator apparatus

Experimental Design

Group A: serving as control for 28 days. Group B: was injected by rifampin I/p-0.8 ml/Kg induced nephrotoxicity for 28 days. Group C: was injected by rifampin I/p-0.8 ml/Kg and treated with the low dose (300mg/Kg) of the methanolic extract of Ambrosia moritima leaves. Group D: was injected by rifampin I/p-s 0.8 ml/ Kg and treated with high dose (600mg/Kg) of methanolic extract of Ambrosia moritima leaves. Serum concentration of urea, creatinine, and electrolytes are measured using commercial kits (Biosystemm S.A Costa Barva 30, Barcelona Spain).

Statistical Analysis

Data were expressed as mean ± standard error of mean (SEM). Statistical evaluation was done using SPSS (version 16.0).

Results

Table 1: Effect of Ambrosia moritima extract administered with Rifampin in the concentration of Serum Urea.

Table 2:Effect of Ambrosia moritima extract administered with Rifampin in the concentration of Serum Creatinine.

We designed the current study to test the hypothesis that Ambrosia moritimam leaves extract could protect against Rifampin (RIF)-induced renal damage in rats through attenuation of inflammation and prevention of oxidative stress. Oral administration of rifampin in dose of 70mg/kg I/p for 28 days to rats caused nephrotoxicity manifested by significant increase (P ˂ 0.05) in serum level of urea, creatinine, Na and K when compared with the (negative) control group. Oral administration of methanolic extract of Ambrosia moritimam leaves for 28 days induced significant (P˂ 0.05) decreases in high serum levels of urea, creatinine (Table 1,2). The concentration os sodium and potassium were increased when the rifampin was injected to the rats, administration of A. moritimam leaves extract resulted in decreased level of both sodium and potassium, however the decrease was marked with the high dose when compared with rifampin intoxicated rats (Table 3,4).

Table 3:Effect of Ambrosia moritima extract administered with Rifampin in the level of Sodium

Table 4:Effect of Ambrosia moritima extract administered with Rifampin in the level of Sodium

Discussion

It has been reported that nephropathy is an important microvascular complication of anti-tuberculosis therapy multiple studies have reported that oxidative stress and inflammation are implicated in drug-induced organ toxicity. However, renal injury induced by anti-tuberculosis therapy is usually reversible and could be treated appropriately if detected early. Therefore, the use of antioxidants could protect against RIF-induced oxidative stress and nephrotoxicity. The results obtained showed that the administration of Rifampin (RIF) has induced renal injury and glomerular dysfunction as evident by the elevated serum urea, creatinine, sodium and potassium levels. These parameters are often regarded as reliable markers of renal damage [6]. In addition, serum creatinine has been used to estimate glomerular function and its elevation is an indicator of renal failure [7]. The elevated serum markers of renal toxicity is agreement with the study of Hashmi et al. [3], who reported increased serum levels of urea and creatinine in albino rabbits following administration of anti-tuberculosis drugs Isoniazid (INH) and Rifampin (RIF) induced nephrotoxicity. In the present study, results suggested that methanolic extract of Ambrosia moritimam 600 mg/ kg significantly reduced Rifampin-induced elevated serum levels of creatinine, urea, sodium, and potassium. The histological findings also supported the nephroprotective action of methanolic extract of Ambrosia moritimam.

Conclusion

It can be concluded that Ambrosia moritimam has anaphor protective effect which might be due to the presence of one or more of flavonoids. In experimental animals several strategies to ameliorate the toxicity have been attempted. These include controlling the time of administration of the antibiotics, modifying the diet and co administering agent to mitigate the renal toxicity.

Read More About this Article: https://biomedgrid.com/fulltext/volume5/the-use-of-ambrosia-moritima-methanolic-extract-as-nephroprotective-against-rifampin-induced-nephrotoxicity-in-rats.000919.php

For more about: Journals on Biomedical Science :Biomed Grid | Current Issue

[dreddymd]

Which plants are effective at treating kidney diseases?

Plant-based foods are much better at promoting health than animal-based foods for a variety of reasons. Besides their abundance in essential nutrients, edible plants also contain a variety of phytonutrients that help combat or treat disease. The ability of these plants to produce antioxidant, anti-inflammatory and other therapeutic compounds serves as their main advantage over conventional medicines, which are chemically synthesized and cause more adverse effects.

Several edible medicinal plants are historically known to treat problems related to the kidneys. According to studies, ancient civilizations used various herbs and functional foods to address kidney stones and kidney disease. To examine their efficacy, Egyptian researchers selected four age-old remedies for kidney-related problems and tested their extracts against chemical-induced kidney toxicity (nephrotoxicity).

Ammi visnaga (khella), Petroselinum crispum (garden parsley), Hordeum vulgare (barley) and Cymbopogon schoenanthus (camel grass) are all medicinal plants commonly used today as food. The researchers found that these traditional remedies for kidney stones are rich in antioxidant compounds that make them effective treatments for nephrotoxicity and chronic kidney disease (CKD). The details of these findings were published in the journal BMC Complementary and Alternative Medicine.

These medicinal foods can protect against inflammatory diseases like CKD

The kidneys are part of the renal system and are responsible for many crucial functions, such as maintaining overall fluid balance, filtering the blood, getting rid of toxins and waste from food or medications and creating hormones that help produce red blood cells.

But because of their constant exposure to toxic substances, the kidneys are always at risk of getting damaged due to nephrotoxicity. Nephrotoxicity, if not addressed properly, can lead to impaired kidney function or even kidney failure.

Khella is a flowering plant from the carrot family and is sometimes called bishop’s weed. As an herbal medicine, khella is often used to treat renal colic. Its main active compound, khellin, is a known smooth muscle relaxant and is effective against urolithiasis.

Parsley is another flowering plant with plenty of medicinal properties. Besides nephroprotective activities, parsley also has antioxidant, anti-inflammatory, diuretic, anti-urolithiasis, anti-cancer and anti-hypertensive activities, according to studies.

Barley is a nutritious cereal grain that offers a lot of impressive benefits. Due to its abundance in dietary fiber, it is often used to help with weight loss. Barley is considered a traditional remedy for urinary stones, diabetes and high blood cholesterol.

Camel grass is a desert plant that was used by the Ancient Egyptians to treat various ailments. Some of its most notable properties include antioxidant, anti-inflammatory, detoxifying, antispasmodic, anti-rheumatic and chemoprotective activities.

To evaluate the ability of these plants to improve kidney health, the researchers first obtained aqueous extracts from each and analyzed their phytochemical content. They then used the extracts to treat mammalian kidney (Vero) cells that had been exposed to carbon tetrachloride (CCl4) to induce renal toxicity.

The researchers reported that the extracts contained varying amounts of phenolic compounds and triterpenoids, as well as vitamin C. These antioxidants allowed the extracts to suppress CCl4-induced oxidative stress significantly by scavenging free radicals and increasing cell antioxidant levels.

All four extracts also significantly reduced CCl4-induced inflammation by inhibiting the expression of associated molecules, such as NF-kB, iNOS and nitric oxide. Additionally, the extracts improved the morphological appearance of Vero cells, cellular necrosis and the expression of kidney injury molecule-1, a marker of renal damage.

The extract from khella reduced CCl4-induced oxidative and inflammatory stress in Vero cells and proved to be more potent than Ketosteril, a synthetic drug used to treat CKD. (Related: Invasive weed from Africa found to be an excellent protective agent for the kidneys, according to new study.)

Based on these findings, the researchers concluded that the edible medicinal plants they studied, especially khella, are promising treatments for nephrotoxicity and other chronic diseases associated with oxidative stress and inflammation.

Evangelyn Rodriguez

Sources include:

Science.news

Healthline.com 1

Healthline.com 2

ChemoCare.com

BMCComplementMedTherapies.BiomedCentral.com

Related Posts

Who needs meds? Simple potassium may lower blood pressure more safely than prescription drugs

Vinegar May Epigenetically Prevent Kidney Stone Development

Water filtration is an essential component to a healthy lifestyle

Sodium Bicarbonate – Full Medical Review

from WordPress https://ift.tt/3hO7CD3 via IFTTT