#multiple sclerosis relapse

[adamslilith]

In July of 2022 I was diagnosed with Multiple Sclerosis and on New Year's eve the same year I ALREADY had my second flare up. On YT I talk about this, the symptoms, the denial.. the treatment, and what this might mean for my future.. here's a sneak peek..

And here's the full video ⬇️

[u2hearts]

A UTI I Should Have Known

Good morning everyone. So, looks like my latest stretch of the last few weeks of suffering might be due to a UTI. Even though we are still waiting on the lab results, my doctor prescribed me antibiotics yesterday. However, when the culture does come back, we might have to change antibiotics based on the strain. I should’ve known. I can’t feel that area anymore yet my aide has said my urine has…

[adamslilith-msart]

Find out more in the video below 🧡

[arrozaurus]

ms changed my worldview because it meant that my future was unpredictability and things that i take for granted today, like my mobility, my senses or my cognitive abilities, may fail me in the long term. i dont know if ill lose them or to what degree. i just cannot make any plans because every plan will backfire no matter what.

idk somehow i just figured that what i have now i would enjoy it to the max. im going to love going up the stairs, im going to love touching the dirt, or im going to do that thing ive always wanted to do but i never dared to because i thought maybe it was not for me. im going up mountains and seeing plants and animals no one ever bothers to pay attention to. im going to love balancing my weight on rocks that are not fixed to the ground just to see if i can.

and because of this my life is probably more enriched that has ever been? sensorially, mentally and physically. and maaan... i could not recommend this enough to someone in the same situation as me

[irresponsible-masochist]

Today is the third anniversary of me being officially diagnosed with MS.

It’s kind of a fucked up thing to keep track of, I guess, but…it feels like it hasn’t been that long, but at the same time, it feels like it’s been much longer.

It’s a weird thing to live with, MS. I feel like I just got to a point where I can accept that I have it. I still mourn the days before-life before I had infusions and medical debt and a fucked up immune system that makes it hard to fight off even a simple ear infection. I hope it will get easier with time, but who knows?

3 damn years I’ve been putting up with MS. 3 years my wife has been putting up with me having MS. I can say that as scary as it is, I’m glad that I’ve always had her. Her love and support have never wavered. Even on my bad days, my hard days, my worst days, she’s been there to love me through it and I have no idea how she’s done it.

3 years of MS Living. I’ll be on this fucked up ride for the rest of my life. At least I’m what they call “stable.” No new lesions, no PML, I’m doing as well as a person with MS can be, and I’ve learned to accept that.

I just hope that I can continue to be “stable.”

[kindajd]

[jamiesonwolf]

A Dance with the Waves

A neighbour gave me a gentle telling off today. For the past three weeks, I’ve been going through a multiple sclerosis flare up. I thought I was just tired at first and suffering from burn out. Then that tiredness became exhaustion. I booked a couple of days off work and was looking forward to getting some much-needed rest. When I woke up on the next day, the fatigue has increased. I had slept…

[sparrow-prophecy]

It's usually the opposite for me. I may be able to stand straight, and lock my body in place, but once I start moving my muscles give out. I may need to keep my legs fairly straight like I'm gooselegging.

#multiplesclerosis #rrms

[exp-market-research111]

Relapsing Remitting Multiple Sclerosis Drug Pipeline Analysis Report 2024

In the United States, around 1 million people are living with multiple sclerosis. Out of these, 80-85% of people diagnosed with multiple sclerosis have relapsing-remitting multiple sclerosis (RRMS), making it the most common sub-type. Therefore, researchers are emphasizing developing high-quality and potent drugs to manage the disease effectively.

Read Full Report with Table of Contents: https://www.expertmarketresearch.com/clinical-trials/relapsing-remitting-multiple-sclerosis-drug-pipeline-insight

This blog provides an in-depth exploration of the relapsing-remitting multiple sclerosis (RRMS) drug pipeline, focusing on market dynamics, external trends, segmentation, growth opportunities, and the impact of COVID-19. Key players like Celgene, Hoffmann-La Roche, Hikma Pharmaceuticals LLC, and Biogen are driving advancements in the development of innovative treatments for this condition.

Relapsing Remitting Multiple Sclerosis Drug Pipeline Analysis Overview

Relapsing-remitting multiple sclerosis (RRMS) is a neurological condition characterized by episodes of worsening symptoms (relapses) followed by periods of partial or complete recovery (remissions). This cycle of relapses and remissions poses unique challenges for disease management.

Key Highlights:

Therapeutic Focus:Current treatments aim to reduce relapse frequency, slow disease progression, and manage symptoms

Emerging therapies include immune-modulating agents, monoclonal antibodies, and next-generation oral drugs.

Pipeline Composition:

A robust pipeline includes over 100 candidates in various phases of development, targeting innovative mechanisms.

Unmet Needs:

While several therapies exist, many have significant side effects or limited efficacy, driving the need for safer and more effective treatments.

Get a Free Sample Report with Table of Contents: https://www.expertmarketresearch.com/clinical-trials/relapsing-remitting-multiple-sclerosis-drug-pipeline-insight/requestsample

Relapsing Remitting Multiple Sclerosis Drug Pipeline Dynamics

Key Drivers Influencing the Pipeline:

Rising Prevalence of MS:

The increasing global prevalence of RRMS has heightened demand for effective therapies.

Focus on Immunomodulation:

Most drugs in development target the immune system, aiming to reduce neuroinflammation and demyelination.

Regulatory Support:

Expedited approvals and orphan drug designations incentivize companies to invest in MS drug development.

Advancements in Molecular Biology:

Improved understanding of the disease's molecular mechanisms has opened new therapeutic targets.

External Relapsing Remitting Multiple Sclerosis Drug Pipeline Trends

Global Trends Driving Market Growth:

Rise of Monoclonal Antibodies:

Therapies like ocrelizumab (anti-CD20) and natalizumab (anti-integrin) are setting the standard for MS treatment.

Collaborative Research:

Partnerships between biotech firms, academic institutions, and pharmaceutical giants are accelerating innovation.

Focus on Oral Therapies:

Oral drugs like fingolimod and siponimod offer convenience and improved patient compliance.

Emergence of Precision Medicine:

Biomarker-driven approaches enable personalized treatment strategies for RRMS patients.

Relapsing Remitting Multiple Sclerosis Drug Pipeline Segmentation

Pipeline Segmentation by Therapeutic Class:

Immunomodulators:

Drugs like interferon-beta and glatiramer acetate modulate the immune response to reduce relapses.

Monoclonal Antibodies:

Target specific proteins to inhibit immune cell activity, such as B-cell depletion.

Next-Generation Oral Therapies:

Focus on reducing neuroinflammation with improved safety profiles.

Pipeline Segmentation by Route of Administration:

Injectables:

Subcutaneous and intramuscular formulations dominate current treatment options.

Oral Medications:

Growing preference for oral drugs due to ease of use and better adherence.

Pipeline Segmentation by Development Phase:

Preclinical Studies:

Investigating novel targets, such as remyelination and neuroprotection pathways.

Phase I, II, and III Clinical Trials:

Assessing safety, efficacy, and optimal dosing regimens.

Pipeline Segmentation by End-User:

Hospitals and Neurology Clinics:

Key centers for administering high-efficacy therapies like monoclonal antibodies.

Outpatient Care Settings:

Focus on long-term management and patient follow-up.

Growth Prospects of the Relapsing Remitting Multiple Sclerosis Drug Pipeline

Factors Driving Market Growth:

Expanding Patient Population:

Increasing awareness and improved diagnostic capabilities lead to earlier detection and treatment.

Innovations in Drug Delivery:

Sustained-release formulations and transdermal patches improve treatment adherence.

Global Investment in MS Research:

Rising funding for neurodegenerative diseases fosters innovation in RRMS drug development.

Pipeline Success:

Promising candidates in late-stage trials are expected to redefine the RRMS treatment landscape.

Recent Developments in the Virus Filtration Market

Virus filtration is critical in the production of biologics and advanced therapies for conditions like RRMS.

Key Advancements:

Enhanced Filtration Technologies:

High-capacity virus filters improve the safety and efficacy of biologic drugs.

Automation and Scalability:

Automated systems streamline production processes, meeting growing demand.

Regulatory Compliance:

Stricter global standards ensure the safety of biologics through improved filtration techniques.

Applications in MS Therapies:

Virus filtration ensures the safety of monoclonal antibodies and other advanced biologics.

Relapsing Remitting Multiple Sclerosis Drug Pipeline Analysis Scope

Key Areas of Focus:

Market Insights:

Analysis of the global RRMS drug market size, revenue forecasts, and regional trends.

Emerging Technologies:

Exploration of innovative drug delivery systems and therapeutic targets.

Competitive Landscape:

Profiling key players, their pipelines, and strategies.

Policy Impacts:

Examination of regulatory frameworks influencing RRMS drug development.

Relapsing Remitting Multiple Sclerosis Drug Pipeline Analysis

Comprehensive Insights Include:

Pipeline Composition:

Overview of drugs across therapeutic classes, development phases, and regions.

Clinical Trial Analysis:

Review of ongoing and completed trials, focusing on efficacy and safety outcomes.

SWOT Analysis:

Strengths: Robust R&D focus and regulatory incentives.

Weaknesses: High costs and limited access to advanced therapies.

Opportunities: Expansion into emerging markets and new therapeutic classes.

Threats: Competition and evolving patient needs.

Impact of COVID-19 on Relapsing Remitting Multiple Sclerosis Drug Pipeline

Pandemic Effects on Development:

Clinical Trial Delays:

Disruption in patient recruitment and trial timelines due to restrictions.

Increased Focus on Neurological Health:

The pandemic emphasized the importance of managing chronic diseases like RRMS.

Digital Transformation:

Adoption of telemedicine and remote monitoring enabled continued care and research.

Shift in Research Priorities:

Resources temporarily redirected to COVID-19 impacted the pace of RRMS drug development.

Key Players in Relapsing Remitting Multiple Sclerosis Drug Pipeline

1. Celgene:

A leader in immunomodulatory therapies, focusing on innovative approaches for RRMS treatment.

2. Hoffmann-La Roche:

Pioneering monoclonal antibody therapies like ocrelizumab for MS.

3. Hikma Pharmaceuticals LLC:

Developing cost-effective solutions and biosimilars for MS management.

4. Biogen:

A key player in MS research, with a diverse portfolio of treatments targeting various stages of the disease.

Frequently Asked Questions (FAQ)

1. What is relapsing-remitting multiple sclerosis (RRMS)? RRMS is the most common type of multiple sclerosis, characterized by relapses (periods of worsening symptoms) followed by remissions.

2. What are the current treatments for RRMS? Current treatments include immunomodulators, monoclonal antibodies, and oral therapies targeting neuroinflammation.

3. Why is the RRMS drug pipeline important? The pipeline addresses unmet needs for safer, more effective therapies to improve patient outcomes and slow disease progression.

4. Which companies are leading in RRMS drug development? Key players include Celgene, Hoffmann-La Roche, Hikma Pharmaceuticals LLC, and Biogen.

5. How has COVID-19 impacted RRMS drug research? While delays in trials occurred, the pandemic accelerated digital transformation and increased awareness of managing neurological conditions.

[sparrow-prophecy]

I have relapsing remitting multiple sclerosis. I filmed this to spread awareness about MS. It hits me hard a few times a week, but most of the time I'm perfectly ok. This was on October 25th (two weeks ago). It's not normal for me to talk like this when I'm having a flare up, but severe movement issues, including speech issues and difficulty breathing are normal for me.

[oliviawebsite]

disabled struggling trans girl in need of help again to stay housed, fed, and medicated

im really sorry for this. last month, out of pure desperation, i took a job that looked promising but ended up being a horrible experience that was way more physical demanding than i was prepared for to the point i agitated my already-existing symptoms and dysfunctions and was forced into resigning because i got to a point where i could no longer physically perform my duties and literally couldn't even walk for several days. i have multiple sclerosis that relapses and remits and obviously i should be on disability but this too is an incredibly long and tiring process, especially considering i have already been denied for it. between that and trying to find some kind of job that i can actually DO its obviously a bit of a tight spot. i have some funds left from when i was working but i need to make up the gap after my bill payments to pay my rent for the month. right now that comes to a figure of a little more than 600 dollars. this way i can at least pay my rent and feed myself at least until my next round of appointments and/or interviews. please help if u can i really dont wanna lose my place in the condition i'm in and i'm so exhausted from being put thru all this ableist capitalist torture labyrinth bullshit. please help or share. thank you i love you i am sorry i will get there someday if i just keep at it

0/600

you can also buy my music if u want some type of material exchange for ur money:

[adamslilith]

Let's talk about paresthesia...

that's the medical term for abnormal sensations of the skin, that is pretty common when you got MS for example..

Now, what I've experienced is ... kind of specific and maybe a little weird, watch the video to find out more and please let me know if you've ever experienced something similar 🤔 

[u2hearts]

Happy 25th Anniversary with Multiple Sclerosis

It started 25 years ago today. The beginning of my major attack that brought about my diagnosis. I still remember the story all too clearly. Valentine’s Day weekend, 25 years ago, I was moving into the house my ex-husband and I bought. We spent a few months sleeping at my mother’s house while updates were being completed. We were ready to move in and be alone in our new home. It was supposed to…

[kikingback]

This Pride month didn't start exactly how I predicted 😅😂

I'm currently (and just provisionally, don't worry!) on my wheelchair again, due to a bad relapse of my multiple sclerosis, BUT it doesn't mean I don't get to show off my flags ✨✨

It's a good time to make people aware of the huge (both material and cultural!) barriers the disabled LGBTQ+ community has to face everyday. There's so much work to make sure we're not forgotten, and we have the right to feel empowered in our true colors ❤️🌈

Happy Pride month to everyone from your friendly neighbourhood Kiki 🏳️‍🌈🏳️‍⚧️❤️🧡💛💚💙💜����🖤

[thornfield987-blog]

I know this has been done before but here’s my headcanons for LU Chronic illness/Disability boys:

Legend(he/they): Hypermobile type Ehlers Danlos syndrome. Frequently dislocates joints and doesn’t see why the others make such a big deal about it, it happens all the time! Primarily suffers from widespread join pain, instability and chronic fatigue. Has as many different mobility aids as they have magical artifacts.

Time(he/him?): Early onset osteoarthritis and partially blind. All of the time travel and shifting forms was not kind to his joints, so the connective tissue was damaged and BOOM. Arthritis. The old man jokes are becoming less and less of a joke every day. Also experiences debilitating migraines.

Hyrule(they/he): Sensory Processing Disorder (often associated with autism but can be caused by other conditions). Their magic sensitivity can often cause overstimulation in their other senses, and they are very sensitive to light, sound, smell and touch. They are semi-verbal because even his own voice can overstimulate him sometimes, but they don’t know sign very well. Also has anemia.

Wild(genderfluid he/she/they): hypertrophic contractural scarring, partially deaf, semi-verbal because of vocal cord scarring. Also prosthetic arm(set after TOTK). She switches between sign and speaking, whichever is easiest for him that day. They have to perform daily stretches and apply scar lotion to be functional, but they aren’t very good at remembering to do so. Often blows out his voice because he gets excited, but can’t tell how loud he is speaking.

Four(plural they/them): Dissociative Identity Disorder(but not really because of magical reasons), damaged growth plates because of Minish magic. They have very similar symptoms to DID, but there are slight differences because it was caused magically and traumatically, not like in the real world. They sometimes struggle to walk correctly because their growth plates are damaged, causing their legs to be slightly different lengths. They wear adaptive shoes to correct this.

Sky(he/him): POTS(Postural Orthostatic Tachycardia Syndrome), chronic fatigue. He struggles to breathe the denser air on the Surface, but he struggled with it on Skyloft as well. He has a chronically higher heart rate that causes dizziness and (rarely) passing out when moving from sitting to standing, after eating, and after adrenaline rushes. This causes his stamina to be fairly low, and also causes chronic fatigue.

Twilight(he/him): RRMS(Relapse/Remission Multiple Sclerosis). This is caused magically by the Twilight curse eating away at his body’s nerves, but is kept mostly under control by his shadow crystal. Occasionally, he goes through relapses and experiences anything from tingling and numbness in a limb to temporary loss of vision in one or both eyes, balance issues, vertigo and slurred speech. These flares are almost always debilitating, but thankfully they only happen every couple of months and last from a few days to about a week.

Wind(he/him?): A little cliche, but he has a peg leg. He likes to tell outlandish stories about it getting bit off by a kraken or eaten by a cannibal, but the truth is that he got an infection, couldn’t treat it in time and had to amputate. This happened sometime after his quests had finished, and he’s still a little ashamed of the actual circumstances, so he doesn’t open up often.

(edit) I FORGOT WARRIORS

Warriors(he/him): Speaking Disfluency (Stutter). Often repeats sounds, such as “G-g-g-guys”, or extends sounds; “Llllllll-Iove you”. He grew up poor, so he was never able to get treatment for it, so he communicates using sign while Proxi translates verbally, though this isn’t as necessary with the Chain since most of them know sign.

[does-truth-matter]

The CDC has quietly changed who should AVOID the MMR vaccine.

https://www.cdc.gov/vaccines/vpd/mmr/public/index.html

They now state that ANYONE that “Has a parent, brother or sister with a history of immune system problems” should AVOID THE MMR VACCINE!

What exactly is an 'immune system problem?" Every autoimmune disorder.

* Achalasia

* Addison’s disease

* Adult Still's disease

* Agammaglobulinemia

* Alopecia areata

* Amyloidosis

* Amyotrophic lateral sclerosis (Lou Gehrigs)

* Ankylosing spondylitis

* Anti-GBM/Anti-TBM nephritis

* Antiphospholipid syndrome

* Autoimmune angioedema

* Autoimmune dysautonomia

* Autoimmune encephalomyelitis

* Autoimmune hepatitis

* Autoimmune inner ear disease (AIED)

* Autoimmune myocarditis

* Autoimmune oophoritis

* Autoimmune orchitis

* Autoimmune pancreatitis

* Autoimmune retinopathy

* Autoimmune urticaria

* Axonal & neuronal neuropathy (AMAN)

* Baló disease

* Behcet’s disease

* Benign mucosal pemphigoid

* Bullous pemphigoid

* Castleman disease (CD)

* Celiac disease

* Chagas disease

* Chronic inflammatory demyelinating polyneuropathy (CIDP)

* Chronic recurrent multifocal osteomyelitis (CRMO)

* Churg-Strauss Syndrome (CSS) or Eosinophilic Granulomatosis (EGPA)

* Cicatricial pemphigoid

* Cogan’s syndrome

* Cold agglutinin disease

* Congenital heart block

* Coxsackie myocarditis

* CREST syndrome

* Crohn’s disease

* Dermatitis herpetiformis

* Dermatomyositis

* Devic’s disease (neuromyelitis optica)

* Discoid lupus

* Dressler’s syndrome

* Endometriosis

* Eosinophilic esophagitis (EoE)

* Eosinophilic fasciitis

* Erythema nodosum

* Essential mixed cryoglobulinemia

* Evans syndrome

* Fibromyalgia

* Fibrosing alveolitis

* Giant cell arteritis (temporal arteritis)

* Giant cell myocarditis

* Glomerulonephritis

* Goodpasture’s syndrome

* Granulomatosis with Polyangiitis

* Graves’ disease

* Guillain-Barre syndrome

* Hashimoto’s thyroiditis

* Hemolytic anemia

* Henoch-Schonlein purpura (HSP)

* Herpes gestationis or pemphigoid gestationis (PG)

* Hidradenitis Suppurativa (HS) (Acne Inversa)

* Hypogammalglobulinemia

* IgA Nephropathy

* IgG4-related sclerosing disease

* Immune thrombocytopenic purpura (ITP)

* Inclusion body myositis (IBM)

* Interstitial cystitis (IC)

* Juvenile arthritis

* Juvenile diabetes (Type 1 diabetes)

* Juvenile myositis (JM)

* Kawasaki disease

* Lambert-Eaton syndrome

* Leukocytoclastic vasculitis

* Lichen planus

* Lichen sclerosus

* Ligneous conjunctivitis

* Linear IgA disease (LAD)

* Lupus

* Lyme disease chronic

* Meniere’s disease

* Microscopic polyangiitis (MPA)

* Mixed connective tissue disease (MCTD)

* Mooren’s ulcer

* Mucha-Habermann disease

* Multifocal Motor Neuropathy (MMN) or MMNCB

* Multiple sclerosis

* Myasthenia gravis

* Myositis

* Narcolepsy

* Neonatal Lupus

* Neuromyelitis optica

* Neutropenia

* Ocular cicatricial pemphigoid

* Optic neuritis

* Palindromic rheumatism (PR)

* PANDAS

* Parkinson's disease

* Paraneoplastic cerebellar degeneration (PCD)

* Paroxysmal nocturnal hemoglobinuria (PNH)

* Parry Romberg syndrome

* Pars planitis (peripheral uveitis)

* Parsonage-Turner syndrome

* Pemphigus

* Peripheral neuropathy

* Perivenous encephalomyelitis

* Pernicious anemia (PA)

* POEMS syndrome

* Polyarteritis nodosa

* Polyglandular syndromes type I, II, III

* Polymyalgia rheumatica

* Polymyositis

* Postmyocardial infarction syndrome

* Postpericardiotomy syndrome

* Primary biliary cirrhosis

* Primary sclerosing cholangitis

* Progesterone dermatitis

* Psoriasis

* Psoriatic arthritis

* Pure red cell aplasia (PRCA)

* Pyoderma gangrenosum

* Raynaud’s phenomenon

* Reactive Arthritis

* Reflex sympathetic dystrophy

* Relapsing polychondritis

* Restless legs syndrome (RLS)

* Retroperitoneal fibrosis

* Rheumatic fever

* Rheumatoid arthritis

* Sarcoidosis

* Schmidt syndrome

* Scleritis

* Scleroderma

* Sjögren’s syndrome

* Sperm & testicular autoimmunity

* Stiff person syndrome (SPS)

* Subacute bacterial endocarditis (SBE)

* Susac’s syndrome

* Sympathetic ophthalmia (SO)

* Takayasu’s arteritis

* Temporal arteritis/Giant cell arteritis

* Thrombocytopenic purpura (TTP)

* Tolosa-Hunt syndrome (THS)

* Transverse myelitis

* Type 1 diabetes

* Ulcerative colitis (UC)

* Undifferentiated connective tissue disease (UCTD)

* Uveitis

* Vasculitis

* Vitiligo

* Vogt-Koyanagi-Harada Disease

Wonder how many doctors are paying attention?

~shared from Jodi Wilson