#is type 2 diabetes genetic

[diabetes-health-corner]

Is type 2 diabetes genetic?

Are you prone to diabetes if it runs in your family? Understand which type of diabetes is genetic. Wondering if diabetes is genetic or not?

Read full blog to know more: https://www.freedomfromdiabetes.org/blog/post/is-type-2-diabetes-genetic/3013

[jacksdinonuggets]

Guys guys guys guys guys

I know this doesnt seem like much BUT

I managed to walk 2.1 miles for 45 minutes WITHOUT GETTING UNMOTIVATED!

This is huge because i could never walk more than 10 minutes without getting bored and losing interest.

So thank you Slipknot and Ice Nine Kills for keeping me motivated!

And to my genetics that gave me very slow metabolism and diabetes:

🖕

[sophsweet]

Government Diet Advice Leads to Yo-Yo Dieting

I searched for anything on government diet advice and yo-yo dieting from misinformation and there was nothing so here goes

Weight management requires both daily activity and eating real food to get essential nutrients. Image by PublicDomainPictures from Pixabay During lockdown, many people went from commuting daily to work, walking to the bus stop, going out during breaks, commuting home or going out. While at work we cannot snack. An entire industry of delivering food to workplaces has grown out of the shorter…

[diabetesreversalprograminindia]

How Genetics Affects Type 2 Diabetes?

This article is originally published on Freedom from Diabetes website , available here. You want to know, is type-2 diabetes is genetic or not? The answer is yes. But it is depend upon some factors. It is something in your environment that actually triggers it. For proof, we can look at identical twins. They have identical genes. Yet if one twin gets type 2 diabetes, the other twin's risk is three in four at most. Lets understand genetic diabetes symptoms?

Frequent need to visit the washroom.

Increase in appetite

Fatigue

Lack of clarity in vision

Repeated infections

healing wounds

Now the question is type 2 diabetes genetic, can it be reversed or not. To know it please click here. If you found this blog useful, please recommend it and share it with others!

Also please connect with me on my website, Facebook page, and YouTube if you want to stay in touch or give me any feedback!

Thank you!

[qurlycueued]

I generally agree with OP, but I'd like to highlight a few points:

Most of the studies OP has linked are anywhere from a decade to almost 15 years old. Generally, this means that the data may not be super reliable for the general population in the present (2023), since methodology may have changed, new studies on the subject may be added, populations may change, etc. Basically-take the claims therein with a grain of salt.

The study looking at if exercise led to weight loss in Type II diabetics noted a significant decrease in visceral fat (the fat around your organs, feels hard like a drum) with exercise than without. Visceral fat, not subcutaneous fat (the softer fat closer to the skin) is what is more concerning medically, as it is associated with metabolic diseases like Type II diabetes. Whether visceral fat is the cause of these diseases or a symptom of it is currently up for debate, though. From what I have read so far on PubMed, inflammation within the fatty tissue is more indicative of problems than the actual fat itself.

The study looking at if exercise led to weight loss in non-alcoholic fatty liver disease (NAFLD) says that the data they found was so biased/sparse that most of the analyses they sought to do were essentially impossible, so we can't really say if exercise impacts weight at all in this group.

The study on computer interventions and weight loss in overweight/obese people was also extremely sparse on data, focused primarily on women, and found that in person interventions were generally more effective at weight loss than computer based ones. However, both are not going to lead to immense weight loss, at least not within a year or two. This is something that the other studies OP linked also found.

TL:DR Most of the claims OP made are verifiable, but take them with a grain of salt since the studies are old and many have unreliable data sources. Exercise may reduce visceral fat in Type II diabetics, but not necessarily overall body weight. We can't really say if exercise does anything to body weight in people with NAFLD.

If you're going to exercise, do it for general health reasons, not for weight loss.

Me: Exercise does not cause weight loss. This is a fact that has been demonstrated so robustly in research that even doctors, who hate and fear evidence, are grudgingly starting to admit this.

Someone reading that post: Cool, but have you considered that exercise leads to weight loss?

Me: I am going to eat you

[petposterous]

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[captainstarburst]

oh yeah i found out recently its diabetes awareness month so ummm. heres a reminder that type 2 diabetes is actually MORE determined by genetics than type 1 and if youve ever made a diabetes joke or talked about it like it's just the stupid fat person disease you owe me $50. disabling lifelong diseases arent funny and they arent any indication of someone's morals and also getting a disease is never anyone's "fault"

[diabetes-health-corner]

Top 10 Frequently Asked Questions on Diabetes Reversal

Type 2 diabetes can be reversed and a sustainable reversal is a reality. FFD's has a large number of people who have not only reversed their diabetes but achieved sustainable reversal! Here is a list of Frequently Asked Questions (FAQs) in relation to Diabetes Reversal.

Click to read more: https://www.freedomfromdiabetes.org/blog/post/top-10-frequently-asked-questions-on-diabetes-reversal/2758

[covid-safer-hotties]

Also preserved in our archive

"No big deal." "Just a cold." "Back to normal."

The proportion of babies born with a congenital heart abnormality increased by 16 per cent after the first year of the pandemic, according to research at City St George's, University of London and published today in Ultrasound in Obstetrics and Gynecology.

Heart defects are the most common type of anomaly that develop before a baby is born, with around 13 babies diagnosed with a congenital heart condition every day in the UK and impacting one in 110 births globally . These include defects to the baby's heart valves, the major blood vessels in and around the heart, and the development of holes in the heart.

In over 18 million births, researchers analysed data from US birth certificates from the Centre of Disease Control and Prevention (CDC) between December 2016 and November 2022 to evaluate the effect of the pandemic on the number of babies born with a congenital heart defect.

They compared the number of babies born with a congenital heart condition every month before the Covid-19 pandemic (1st December 2016 to 30th November 2019) with those during the pandemic (1st December 2020 to 30th November 2022).

This data was then compared to the number of babies born with Down's Syndrome - a genetic condition not affected by the virus. This was to help ascertain if any differences observed might have been due to Covid-19, or if they were a result of other factors including limited access to antenatal services during the pandemic.

A total of 11,010,764 births before and 7,060,626 births during the pandemic were analysed. Data was adjusted to account for mother's BMI, diabetes and blood pressure before pregnancy, age, number of times they had given birth and the season in which prenatal care started.

The number of births with a congenital heart condition increased by 16% after the first year of the pandemic, with 65.4 cases per 100,000 live births compared to 56.5 per 100,000 births in the period studied before the pandemic.

The number of babies born with Down Syndrome did not change for the duration of the study, suggesting that the increase in fetal heart defects were not due to a disruption of health services.

Studying this large US dataset has revealed an unexpected picture for how the pandemic has affected the hearts of unborn babies, but we need to untangle the reasons for this link. We need to determine if the SARS-CoV-2 virus directly causes the development of fetal heart problems during pregnancy, and if so, how the virus makes these changes in the heart.

We don't have this type of data set available in the UK, but it's important to see if this pattern is seen in other parts of the world.

Covid-19 is still circulating and is easier to catch in the winter months. These results act as an important reminder for pregnant women to get their Covid-19 vaccinations to help protect themselves and their baby."

Professor Asma Khalil, lead author and Professor of Obstetrics and Maternal Fetal Medicine at City St George's, University of London

Source: City St George's, University of London

Journal reference: Khalil, A., et al. (2024). Congenital heart defects during COVID‐19 pandemic. Ultrasound in Obstetrics & Gynecology. doi.org/10.1002/uog.29126. obgyn.onlinelibrary.wiley.com/doi/epdf/10.1002/uog.29126

[mindblowingscience]

The levels of caffeine in your blood could affect the amount of body fat you carry, a factor that in turn could determine your risk of developing type 2 diabetes and cardiovascular diseases. Those are the findings of a 2023 study that used genetic markers to establish a more definitive link between caffeine levels, BMI, and type 2 diabetes risk.

Continue Reading.

[championlaura222]

I'm sick of the moraliazation of illness/disability. I see it a lot when it comes to type 2 diabetes. I'm sick of the idea that it's just "fat person disease." Talk to pretty much any doctor and they'll tell you that the main factor in type 2 diabetes is genetics. My mom's side has a higher likelihood for type 2 diabetes, my dad's side does not. Despite my dad being extremely overweight for much of his life, not even a sign! My Nan had some weight gain in her 50s, not that much from how much she weighed, and she ended up with it. There's no "right" way to be ill, I'm tired of the stigma around the idea that a person "does it to themselves" and thus is okay to ridicule and not listen to. In fact, Weight in general has more to do with genetics than most other factors! Think about how many people live off redbull and fast food and don't gain weight from it! And even if someone did get sick because of their actions, you shouldn't go around ridiculing them over that!

[intersex-support]

hi! Im uhm kinda questioning if I might be intersex? I have hyperandrogenism and clitoromegaly as diagnosed conditions, but my doctors say they come from a genetic complication from my diabetes. I have a rare genetic mutation, which means I don't have type 1 or 2 type diabetes, but rather type A insulin resistant diabetes. Im not sure if that would mean I can't be intersex because I've only seen things about PCOS so far, but the term intersex comes up when ever i search up my conditions. I was assigned afab and seemed totally normal until puberty and started growing facial hair. It's not a lot but its noticeable. I just wanted to see if the term intersex may applie to me? Sorry if this seems like a dumb question.

Hi anon! It's not a dumb question.

So, I wasn't familiar with Type A insulin resistance before this question, but I did some research to become more familiar with it. And based on everything I learned, I do think that this is a diagnosis that could be considered an intersex variation. Like you shared, it causes hyperandrogenism and clitoromegaly, which are often intersex traits.

I like InterACT's definition of intersex: "a variation that:

shows up in a person’s chromosomes, genitals, gonads or other internal reproductive organs, or how their body produces or responds to hormones;

Differs from what society or medicine considers to be “typical” or “standard” for the development, appearance, or function of female bodies or male bodies; and

Is present from birth or develops spontaneously later in life."

I think that insulin resistance A would meet all those criteria: it's a variation in how your body produces or responds to hormones that differs from what society considers "standard" sex traits for those assigned female at birth, in a way that might bring stigma or discrimination, and it is a lifelong variation, not something temporarily caused by medication or something like a tumor. Insulin resistance A isn't usually listed on intersex variation lists, but I honestly think that's because it's rare enough that orgs just aren't aware of it, and hadn't thought to research it because diabetes in general isn't an intersex variation.

Ultimately, I think it's up to you--if you don't feel comfortable identifying as intersex you don't have to, but in my opinion, you're welcome to identify as intersex, and I think you'd find a lot of shared community with other intersex people who might experience similar symptoms or life experiences. If you wanted to start exploring intersex community spaces, I think you'd find a lot of people who would accept you. Your journey is your own journey and there's no timeline or pressure to do anything, but you absolutely would count as intersex from my perspective.

Please feel free to reach out if you have any other questions, and wishing you the best of luck, anon!

[scientia-rex]

Wound Care

Ok so, take this with a BIG grain of salt, because I may be a medical doctor BUT you need to know how much wound care training we get in medical school: none. Zip. Zilch. There may be medical schools where you do, but mine wasn't a bozo factory and there was NO wound care training. Everything I know I learned from one of several sources: an intensive 2-day wound care course I did in residency (highly recommend), the local Home Health wound care nurse (highly recommend), a completely batshit insane old white male doctor who started our learning sessions by yelling Vietnam War stories at me (do not recommend), a hospital wound care nurse (highly recommend), and experience (oh god do not recommend).

The first thing you need to know is that wound healing varies dramatically across the course of a lifespan. Kids? Kids will heal. If they don't, get their ass to a pediatrician because there's something genetic going on. Young adults will heal. Middle-aged adults will heal. You know who doesn't heal for shit? The elderly, and people with severe illnesses, and people with uncontrolled type II diabetes.

Your body needs several things in order to heal. It needs macronutrients, so you need to be able to EAT protein, fat, and carbs. If you are on total parenteral nutrition, aka TPN, aka IV nutrition, you are going to be worse at healing. If you are starving yourself, you are going to be worse at healing. If your body is desperately funneling all the calories you take in to surviving your COPD or cancer, you are going to be worse at healing.

It also needs micronutrients. If your diet sucks, you won't heal. Take a multivitamin once in a while.

There are two CRITICAL skin components to healing: collagen and elastin. Guess what we stop making as we age. Promoting collagen isn't just good for "anti-aging," it's good for NOT ripping your skin apart. Taking oral collagen is probably bullshit because your body is going to have to disassemble it to get it across the intestinal membranes to absorb, but it's also harmless, and if your diet REALLY sucks, who knows. Give it a try. Collagen is made of amino acids; think protein.

Another absolutely crucial component is blood flow. As people age, they start to develop cholesterol plaques lining arteries that eventually pick up calcium deposits. This makes blood vessels less elastic, which is a problem, but eventually also blocks them off, which is a much bigger problem. If someone has the major blood flow to their feet decreased by 90% by arterial stenosis, they are not going to heal for shit AND their foot's gonna hurt.

One component of blood flow I hadn't thought about before going into medicine is fluid retention. The way your body works, blood exits the heart at a very high velocity, but slows to a crawl by the time it gets into capillaries, the smallest blood vessels in the body. Water is a very small molecule and can leave the blood vessel, especially if there aren't big, negatively-charged molecules like proteins like albumin in the blood vessels to hold the water there. And we're built for this--some water is supposed to leak out of our blood vessels when it gets to real little vessels. It gets taken back up by the lymphatic system and eventually dumped back into the bloodstream at the inferior vena cava. But if you aren't making albumin--for instance, in liver failure--you may leak a LOT of fluid into the tissue, so much that your legs get swollen, tight, the skin feeling woody and strange. This isn't fixable by drainage because the fluid is everywhere, not in a single pocket we can drain. And because it puts so much pressure on the tissues of the skin, it often results in ulcers. Congestive heart failure, liver failure, kidney failure--these are all common causes of severe edema, aka swelling due to fluid in the tissues. And they're a real bitch when it comes to wound care, because we have such limited resources for getting the fluid back out, which is a necessary first step to healing.

Pressure is another common cause of wounds. Pressure forces blood out of those little capillaries, so you starve the cells normally fed by those capillaries, and they die. It's called pressure necrosis. Very sick people who can't turn themselves over--people in the ICU, people in nursing homes--are especially prone to these wounds, as are people with limited sensation; pressure wounds are common in wheelchair users who have lost some feeling in the parts of their bodies that rub against those surfaces, or diabetics who don't notice a rock in their shoe.

So, if you're trying to treat wounds, the questions to ask are these:

Why did this wound happen?

-Was it pressure? If it's pressure, you have to offload the source of the pressure or else that wound will not heal. End of story. You can put the tears of a unicorn on that thing, if you don't offload the pressure it won't heal.

-Was it fluid? If it's fluid, you have get the fluid out of the issues or else it won't heal. You can sometimes do that with diuretics, medications that cause the body to dump water through the kidneys, but that's always threading a needle because you have to get someone to a state where they still have juuuuust enough fluid inside their blood vessels to keep their organs happy, while maintaining a very slight state of dehydration so the blood vessels suck water back in from the tissues. You can use compression stockings to squeeze fluid back into the vessels, but if they have arterial insufficiency and not just venous insufficiency, you can accidentally then cause pressure injury. The safest option is using gravity: prop the feet up above the level of the heart, wherever the heart is at, at that moment, and gravity will pull fluid back down out of the legs. Super boring though. Patients hate it. Not as much as they hate compression stockings.

-Was it a skin tear because the skin is very fragile? This is extremely common in the elderly, because they're not making collagen and elastin, necessary to repairing skin. If this is the case, make sure they're actually getting enough nutrition--as people get into their 80s and 90s, their appetites often change and diminish, especially if they're struggling with dementia. And think about just wrapping them in bubble wrap. Remove things with sharp edges from their environments. I have seen the WORST skin tears from solid wood or metal furniture with sharp edges. Get rid of throw rugs and other tripping hazards. I had somebody last week who tried to a clear a baby gate and damn near destroyed their artificial hip.

The next critical question: why isn't it healing?

-Are you getting enough nutrients? Both macro and micro?

-Are you elderly?

-Are you ill?

-Do you have a genetic disorder of collagen formation?

Fix why it's not healing and almost anything will heal. If you're diabetic, find a medication regimen that improves your sugars and stick to it. If you're anorexic, get treatment for your eating disorder. If you have congestive heart failure, work with your doctor on your fluid balance. Wear the damn pressure stockings. Prop up your feet.

If, after those two unskippable questions are done, you want to do something to the wound--apply a dressing, do a treatment--that's a whole other kettle of fish. I'll write that later. The dryer just sang me its little song and I need to put away the laundry.