#interesting look

[naorende]

[faeriekit]

"This fic was ai generated—" Cool, so lemme block you real quick

[unsung-idiot]

don't show him modern technology; it won't end well

bonus under the cut:

[3liza]

love when im watching a documentary and im like "yep thats an egyptologist alright"

[frankierotwinkdeath]

Y’all want Taylor Swift to be gay so bad but you won’t even write femslash about her

[noodles-and-tea]

Continuation of this

[daydreamerwonderkid]

Bruce used Awkward Flirtation. It's a Critical Hit!

Reference under cut

[rdps01]

close enough

[chloesimaginationthings]

What if Henry found Springtrap first in FNAF..

[nothatsmi]

The foxhole court, chapter five

First books monsters were something really.

On an aftg reread, which is very useful to survive school these days. Currently into the raven king, i'll make more fanart cause this brings me so much joy (which - idk what it tells about my mental state). If you have suggestions on what I should draw next I'm taking em.

[biggest-gaudiest-patronuses]

best thing about batman is that he's a superficially grimdark character, gothic & brooding & angst ridden etc..........but then it turns out he has a million hobbies, regularly goes on adventures with his besties, and has a dozen adopted kids he's raising with his devoted foster dad. good for him

[buglaur]

[twofoursixohjuan]

please elaborate in tags :)

[cidnangarlond]

[reasonsforhope]

A new treatment combining ReCET and semaglutide could eliminate the need for insulin in type 2 diabetes, with 86% of participants in a study no longer requiring insulin therapy. The treatment was safe and well-tolerated, and further trials are planned to confirm these results.

Groundbreaking research presented at UEG Week 2024 introduces a promising new treatment approach for type 2 diabetes (T2D) that has the potential to greatly reduce or even eliminate the need for insulin therapy.

This innovative approach, which combines a novel procedure known as ReCET (Re-Cellularization via Electroporation Therapy) with semaglutide, resulted in the elimination of insulin therapy for 86% of patients.

Globally, T2D affects 422 million people... While insulin therapy is commonly used to manage blood sugar levels in T2D patients, it can result in side effects... and further complicate diabetes management. [Note: Also very importantly it's fucking bankrupting people who need it!!] A need therefore exists for alternative treatment strategies.

Study Design and Outcomes

The first-in-human study included 14 participants aged 28 to 75 years, with body mass indices ranging from 24 to 40 kg/m². Each participant underwent the ReCET procedure under deep sedation, a treatment intended to improve the body’s sensitivity to its own insulin. Following the procedure, participants adhered to a two-week isocaloric liquid diet, after which semaglutide was gradually titrated up to 1mg/week.

Remarkably, at the 6- and 12-month follow-up, 86% of participants (12 out of 14) no longer required insulin therapy, and this success continued through the 24-month follow-up. In these cases, all patients maintained glycaemic control, with HbA1c levels remaining below 7.5%.

Tolerability and Safety

The maximum dose of semaglutide was well-tolerated by 93% of participants, one individual could not increase to the maximum dose due to nausea. All patients successfully completed the ReCET procedure, and no serious adverse effects were reported.

Dr Celine Busch, lead author of the study, commented, “These findings are very encouraging, suggesting that ReCET is a safe and feasible procedure that, when combined with semaglutide, can effectively eliminate the need for insulin therapy.”

“Unlike drug therapy, which requires daily medication adherence, ReCET is compliance-free [meaning: you don't have to take it every day], addressing the critical issue of ongoing patient adherence in the management of T2D. In addition, the treatment is disease-modifying: it improves the patient’s sensitivity to their own (endogenous) insulin, tackling the root cause of the disease, as opposed to currently available drug therapies, that are at best disease-controlling.”

Looking ahead, the researchers plan to conduct larger randomized controlled trials to further validate these findings. Dr. Busch added, “We are currently conducting the EMINENT-2 trial with the same inclusion and exclusion criteria and administration of semaglutide, but with either a sham procedure or ReCET. This study will also include mechanistic assessments to evaluate the underlying mechanism of ReCET.”

-via SciTechDaily, October 17, 2024

--

Note: If it works even half as well as suggested, this could free so many people from the burden of the ongoing ridiculous cost of insulin. Pharma companies that make insulin can go choke (hopefully).

[isjasz]

[Day 365 | Ref to Day 1]

And that's a wrap 🪻🥀

===

fhksjdkwjw ITS OVER. ITS OVERRRRR I MADE ITTTTT

Screaming and losing it. It only started to feel real as I'm posting this rn HRKSJAKSJLELH. A year... 365 pieces (probably a bit less bc I did post wips?) of desert duo... I would make a collage maybe but its prob a lot of work HJASKDHAHEHW

🫵 @vesperionnox @cherrysherin without u guys I wouldn't have been here <3 This challenge kinda became its own thing at some point, but I didn't forget where I started :D

💥💥💥 AAA I hope you guys enjoyed this challenge as much as I did!! but also WOOOOOOOOOOOOO FREEDOM. I WILL DEF STILL BE DRAWING DESERTDUO THO LOL BUT LETS FREAKING GO ONE YEARRRR