In the Endosome
Greater understanding of G-protein signalling – molecular programs involving cell organelles called endosomes that regulate physiological processes throughout the body such as water re-absorption via the kidney
Read the published research paper here
Image from work by Carole Daly and colleagues
Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, UK
Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
Published in eLife, October 2023
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Cellular fate and energy factories: unraveling how surface receptors meet mitochondria for brain cell survival
The human brain is an organ that takes nearly from 20 to 25% of the energy the body needs. This high energy demand for neuronal functions depends on the transport and precise distribution of mitochondria — the energy-generating cell organelles — in each neuron. In neurons, the transport process of mitochondria is determining, since these organelles must be present along all axons and dendrites to…
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G PROTEIN APPRECIATION POST
And by extension GDP, GTP, AC, cAMP, and PKA
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These regulatory GTPases are molecular switches that can cycle between an active, GTP-bound form and an inactive, GDP-bound form (Figure 21.15A). (...) Figure 21.15B illustrates a proposed mechanism by which a pollen-expressed RLK interacts directly with GEF to control tip growth.
"Plant Physiology and Development" int'l 6e - Taiz, L., Zeiger, E., Møller, I.M., Murphy, A.
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Disordered ahh birthday
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all i'm asking for is that if we get a event in the philippines and there's a Storm there we should have a soundtrack that's a mashup between symbiosis and it's raining in manila
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Thr thing abt me is that I want to know exactly how psychiatric medications work. I don't want the simplified version. Dont give me the "I'm talking to the public" answers. I want the specific mechanisms and how exactly it causes its side effects.
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can someone do me a favor and just inject the experience of watching one piece pre ep 972 ok thx
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Two double cheese burgers and a protein shake for breakfast because I need to be bulky as fuck yesterday. Thinking about how much I’m growing and how much I NEED to outgrow size large to be a fucking tank.
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I had the rest of my mac and cheese but it wasn't enough...would it really be so wrong to make another box. would it really be so wrong
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Serotonina e psichedelici: sono allucinogeni solo se si accoppiano al segnale cellulare giusto
L’interesse per le sostanze psichedeliche classiche o serotoninergiche è riemerso, dato il loro potenziale di indurre effetti terapeutici rapidi e prolungati. Le sostanze psichedeliche sono limitate dai loro effetti allucinogeni e possono causare confusione e ansia. Sebbene un recente studio preclinico abbia suggerito la possibilità di separare le sostanze psichedeliche dalle loro proprietà…
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trying to find ways to eat protein that won't trigger my acid reflux, i got to like 72g yesterday but at what cost
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29/sep/23: ana log + thíńśpó ♡
weight: ♡lost .5kg (1lb) —47.3kg/104lb
fasted workout: 100 crunches, 40 plié squats, 20 push ups: -41
—♡18 hour fast completed!
breakfast: 2 eggs, 60g of rice, 1/2tblsp of olive oil extra virgin: 328
lunch: 1 fuji apple: 107
—16 hour fast started!
!! all workout calories are estimates and some idk! :( !! workout: 1 min 20 sec plank (3), 100 heel touches, 100 crunches (26), 100 glute bridges: -29
steps: walked 3.1km: -150
!! bmr: 1284
total intake: 435 and total burned: -1526
net: -1091 ♡
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id like to thank my school counselor for supporting my lunch today by donating a cliff bar
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in this cruel cruel life there is one joy to look forward to
$2.69 costco pizza and soda
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