#formulation and development
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renejix58 ¡ 6 months ago
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thewitfire ¡ 1 year ago
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How to Formulate Microemulsion? SOP for Microemulsion
How to Formulate Microemulsion? SOP for Microemulsion. #Microemulsion #sciencenews
How to Formulate Microemulsion: Introduction to Microemulsions Definition and Overview How to Formulate Microemulsion: Microemulsions are fascinating colloidal systems, characterized by their clear and thermodynamically stable mixture of oil, water, and surfactants, often accompanied by a co-surfactant. These systems are isotropic and typically feature droplet sizes within the range of 10-100…
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amethystina ¡ 8 months ago
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hello dear, hope you're doing well physically & mentally. lots of hugs for you!
i've been wondering about the physical touch in Gahan's dynamic especially. we all know how much physical abuse Yohan has gone through in his childhood, the kidnapping by Sunah, him willingly explode a whole ass room with bombs with him inside it too but pushing away his loved one out.
now compare to Gaon. this Bambi has better experience with physical touch in his life seeing as how he's comfortable leaning to Soohyun seeking comfort while grieving for the loss of his parents. reaching out to Yohan so easily when he sees Yohan woke up from a nightmare. how he reaches for Kkomi and put her on his lap, the lovely and respectful interaction with Elijah.
I always have this thought in my head that it would be tricky for them to have this physical touch without one misunderstood the meaning of one's action. personally i bounced back and forth of the idea Yohan can manipulate and charm ppl with his sex prowess. just because he knows being seduction and sex goes hand in hand with manipulation. It does seem like Yohan can be the type to do especially that the way he gazes at Gaon & Sunah. But we all know he has brother complex lol, while with Sunah he can get the rush of feeling powerful having someone around his level to play with. Either that idea or I think Yohan never has the chance to explore sex bcs it's too much physical touches and too much emotional investment in such a short period of time. Perhaps he can have sex while his sex partner is tied up, not touching Yohan but he's the one who has control to touch them, hence why the kinky dom Yohan exist. So i think domestic touches will be like taming stray or feral creatures. It would take a long time and patience on both sides to be in the safe space and trust.
now.. wdyt Gahan would be in if they were already in a romantic relationship. How would they interact? Who would initiate what? What difference would it be for them in domestic/ innocent interactions and in bed? I would like to know your thoughts on this one. I wish I can pour my detailed thoughts for this but i'm afraid to scare you off with my long-ass paragraphs hahaha it's been a while since I have conversations analyzing character's personality and their depths, just geeking out about them and it can be intense and intimidating for people if I pour all my thoughts out for these shit lol
I wish you well! Take your time on your recovery & in writing, we'll always be here for you!
I'm currently in pain from shoveling too much snow but, other than that, I'm pretty okay. Thank you for asking 💜
Physical touch is a very fascinating subject when it comes to these two, isn't it? Probably because there's so much tension between them.
Anyhow! I actually think that Yo Han has had a lot of sex but, like, only with the right people? He may have been abused as a child (and definitely has trauma and trust issues because of it) but he's also a very clever and intuitive man. And he'd know how to find partners he can have casual, enthusiastic, and fun sex with. Like, some random woman or man he meets at a bar who thinks he's hot? Definitely. Some random woman or man he meets in a professional setting who is clearly trying to gain something from having sex with him? Absolutely not.
Having sex is a very intimate act in some ways, but exactly how intimate depends a lot on the partner, the setting, and the circumstances. Yo Han would only go for people he's not feeling threatened by or knows he can control without exerting too much effort. But I also think he'd enjoy the challenge of wooing people. Like, how fast can he make this woman shed her clothes? What should he say to make this man swoon? Flirting would be a game for him, too, but "winning" just means he and the other person get to have sex so it's actually pretty harmless.
And I think he'd be fine doing it with strangers and letting them touch him. Because he doesn't actually seem averse to touch in the drama? Unused to it, yes — especially the tender kind — but not scared of or uncomfortable with it. He puts himself and his body through a lot, yes, but never in a reckless or self-destructive way. More often than not, he knows exactly what the risks are and deems them worth whatever payoff comes at the end (unlike Ga On who just... throws himself into danger without much thought).
One of the few (if not the only time) Yo Han seems genuinely scared of physical touch is when Ga On tries to comfort him after his nightmare. Which says a lot, I think. He's more scared of a touch meant to soothe than one meant to hurt, since he doesn't want to show weakness. He doesn't know how he will react to a touch like that and would therefore rather push it away.
But he doesn't even flinch when Sun Ah raises a hand to slap him, which is definitely a situation where some (but not all) who have been abused in the past would react. So, clearly, he's not as traumatised as he could have been, or has learned to control it enough for it not to show too much. To me, Yo Han doesn't seem averse to casual touching and does it quite a lot himself, like towing Ga On around at the gala, lightly patting Lawyer Ko's arm, offering his arm to Jin Joo at the other gala etc.
And I personally don't think there will be all that many misunderstandings between him and Ga On as to what a certain touch means? They both seem way too smart for that? There might still be general misunderstandings, of course, but not when it comes to that. If nothing else, the intent behind touches is something Yo Han had to learn long ago because you can't manipulate people only using sexual prowess. He needs more than one method and that means recognising what different touches mean, when to give them etc.
My personal headcanon for Yo Han is that he has no trouble using his sex appeal to manipulate when appropriate, but his strength lies in how he adapts to the situation, sometimes being kind and understanding, sometimes being firm and commanding, and, sometimes, being flirty and sensual.
The way he prefers to have sex is for fun, though, and he enjoys it a lot with the right people. But he'd never do it if he felt uncomfortable or threatened by his partner, and he's good enough at reading people that he'd know the other person's intentions long before the actual sex happens. So, for example, I don't think he'd ever want to have sex with Sun Ah even if he could tie her up. He'd be too suspicious to actually enjoy it xD
To me, Yo Han is the kind of man who has a lot of trauma, but has also worked a lot on overcoming said trauma. If he did so in a healthy way I will leave unsaid, but I don't think he'd allow himself to be wary of other people's touch. I think Yo Han would be frustrated by his own limitations if he could only have sex with people while they're tied up, simply because he's uncomfortable with them touching him. That's too big of a weakness — something someone could exploit. And he'd train that out of himself as soon as possible. His whole thing is that he's unshakeable and impenetrable and that's a choice — something he's putting effort into being. And so I, personally, can't see him allowing himself to have that kind of "flaw."
As a friend of mine said: "He's a man even more in control of himself than he is others."
That said, I think he enjoys tying people up because it gives him added control and makes it more fun to play with his victims partners. So I'm all for Dom!Yo Han — he is one in every fic I've written so far — I just think he does that because he likes it, not because it's the only way he can have sex.
And, to be entirely honest with you? I don't think Yo Han needs to tie people up in order to control them in the bedroom. I'm pretty sure that man can make his partners do pretty much anything he wants them to, without using a single tool or restraint. Because that is the kind of Dom he is.
ANYHOW. To your questions! (boy did I get derailed there for a while)
Ga On is definitely the cuddly one. Like, once he gets comfortable, he's the one who gives and asks for hugs, will walk up behind Yo Han and wrap his arms around him, snuggle up on the couch, put his head in Yo Han's lap etc. Because I definitely agree with you that the casual, domestic touches will be more difficult for Yo Han. He's used to giving some of them, like pats on the shoulder, a supportive hand, fixing Ga On's clothes — practical things. But the ones that are just because? Clearly, that's out of his wheelhouse and he's too prideful to ask for them.
Again, not because he's broken, scared, or doesn't understand them, but simply because he's not used to them. And he doesn't like feeling insecure or appearing weak, so he wouldn't risk asking and making a mistake.
So it'll fall upon Ga On to offer them, which he of course does. He's a pretty physical person with the people he trusts, provided that politeness and such allows it. Like, clearly, one of the reasons why Ga On doesn't touch Yo Han much in the drama is due to the workplace hierarchy, the fact that Yo Han is older (and it's considered rude to touch someone older without their permission), and just Yo Han's overall... Yo Han-ness. But once Ga On gets free rein?
Yo Han won't know what hit him.
But it'll take time for them to get used to it, yes. Like, just teaching Yo Han how to return casual hugs that aren't in a life-or-death situation is going to take a while. But he'll get used to it eventually and while I don't think he'll ever be the one to initiate certain things — like the more cuddly hugs that might make him look clingy — he'd always reciprocate when Ga On does.
Yo Han is a little too prideful to ask for cuddles, but he'll graciously agree to them when Ga On asks him to give them.
(He and Komi have that in common, I guess)
As for sex, that depends? I think they can both initiate it, but Yo Han enjoys it more when Ga On does so, just because he likes seeing Ga On horny and desperate xD Yo Han is definitely the one in charge, though. That's not to say that Ga On can't snatch control from him or throw him off-balance from time to time, but probably only during brief moments when he's being particularly cheeky and bratty. I think they both enjoy the push-and-pull — the fact that Ga On challenges Yo Han is a part of the thrill — but are more comfortable when Yo Han is in control.
Especially since Yo Han is very good at it.
All that said, I do think — and this might be an unpopular and scandalous opinion — that Yo Han could, eventually, let Ga On top him. But we're talking years down the line, when they're so comfortable with each other that there are no secrets or doubts. Because, yes, Yo Han is a man who prides himself on having control but, eventually, he's also going to realise that having control and having power isn't necessarily the same thing. And being in charge and having control isn't necessarily the same thing, either. Ga On has a tremendous amount of power over Yo Han despite not being in charge or in control the majority of the time.
I mean, there's a reason why they say that the sub is the one with the real power since they're the ones willingly handing it over to someone else. And if they can give it, they can also revoke that privilege — and there is absolutely nothing the Dom can do about that. In that situation, the Dom is, quite literally, powerless.
And I think, especially as he gets older and softer, Yo Han would realize that trusting Ga On to top him is, in fact, a sign of his own strength. And I don't mean that in a "real men know how to bottom" kind of way. But in a "I love this man and I trust him and myself enough to let him have this power over me because that, in itself, means I have power."
But, again, that's several years into their relationship and 99,9% of the time, Yo Han is the one topping. But, every once in a while, Ga On can be the one in charge. As a treat.
... I may have gotten off track again.
But I'd say that's about the gist of it? There are, of course, more specific examples and details, too.
Yo Han is definitely the one doing most of the dirty talk, but Ga On will not hesitate to use his doe-eyes to his advantage and say the most kinky, outrageous things sometimes, just for the pleasure of watching Yo Han bluescreen. I also think that Yo Han will develop a habit of burrowing his nose in Ga On's hair when they're hugging/cuddling. And, as I've mentioned in a previous post, Yo Han is the little spoon 90% of the time. I also think that Ga On is going to be pretty shy and prudish when it comes to talking about sex and anything relating to it (at least at the beginning), but kinky as fuck when it comes to the actual acts. Like, he can't say "cock" without wincing, but he'll gladly let Yo Han tie him up and fuck him so roughly and thoroughly he's covered in bruises afterwards.
I really could go on but then we'd be here forever and I have work tomorrow x'D
So I'm hoping you got something out of this long rant! Thank you so much for the ask! I admit that I don't often spend time thinking about fictional characters' sex lives, but I apparently have a lot of opinions regardless. Though, to be honest, I think Yo Han and Ga On is the couple where I've had to think about it the most, since physical closeness (of both the sexual and more innocent kind) is extremely important for their dynamic. So yeah.
Take care, darling! 💜
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txttletale ¡ 2 years ago
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what’s the difference between Marxism and Marxism-leninism
lenin, mostly
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voidrifter ¡ 1 month ago
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hi3 pt.2, chapter v spoilers:
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well okay then!
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afterthefeast ¡ 11 months ago
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ok u guys weren’t kidding scherzo really is something else
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atformulation1 ¡ 7 months ago
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frigidlyauthorial ¡ 2 years ago
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also they keep showing sentimonsters being made to look and act entirely human. adrien honey i am so sorry but this is not looking good for you
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spectroscopes ¡ 2 years ago
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I forgot how much I enjoy being a film bro but honestly the best part of it this time around is actually just privately developing my opinions about a movie I just watched inside my own head or with a couple of cherished friends and not feeling like I have to contribute to the discourse or even have an especially solid take.
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raidante ¡ 2 years ago
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I’m embarrassed by how invested I am in my own work… bruh
#Listen growing up I think the biggest thing I struggled with was making my own work#That I didn’t consistently abandon#My friends all made ocs for everything they liked and half the reason I ever did#Was just to join them rather than care explicitly about it myself#I have a few fandom ocs I’ve actually invested in as I’ve gotten older / revisited#My sonic and splatoon ones for instance#I’ve actually grown them and build backstories and personalities#But like these characters and scenario I’ve made has been consistently swirling in my brain for months.#The way it’s developed because I was THAT disappointed in smtv LOL#Bc my protag started out as what I wanted the Nahobino to look like#Over time became less and less attached until I finally pulled the plug and set it free as my own character#And I’ve loved him and developed him sooooo much more since I’ve done that#I just wish I was better at formulating all of this#Because I think it can only exist in the form of a game#A very specific looking game#With specific puzzles and camera angles and music#But I don’t know how to game#So it’ll probably be stuck in concept form forever#Unless Atlus wants to buy it LOL <- doubt#Anyways I’ll continue to develop it all. Get better at art so I can draw environments and scene mock-ups#I wish it was a real game T_T#Oh well#I’m glad some people are interested in my own journey#Exploring my own creativity#Pouring my own philosophies#Txt
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foodresearchlab ¡ 2 years ago
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Formulation of herbal water with zero caloric sweeteners and natural colors and flavors. This case study focuses on:
Formulation of the herbal beverage that has good sensory properties
Extension of the shelf life of the product
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rp18hplc ¡ 1 year ago
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@rollsrocker thanks, uhh I love this!!!
it went from a philosophical discussion to pharmacist dumping their knowledge!!! let's add some more in the tags 😁
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chemxpert ¡ 8 days ago
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Your Gateway to Global Pharma Insights | Chemxpert Database
Uncover opportunities in the pharmacy industry with Chemxpert Database, the ultimate resource for pharmaceutical excellence. Access insights on the top 10 API pharma companies in the world, explore pharmaceutical industries near me, and grow your medicine wholesale business with ease. Stay ahead with connections to top medical device companies and discover sources for low-cost medications. Chemxpert Database empowers your journey in pharmaceuticals and medical innovation, offering unmatched resources for success.
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colinwilson11 ¡ 2 months ago
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Ophthalmic Drugs Contract Manufacturing: An Overview Of The Rapidly Evolving
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Regulatory compliances play a pivotal role in ophthalmic drugs manufacturing due to stringent norms and quality standards set by regulatory bodies like US FDA, EMA, etc. Ophthalmic products manufacturing needs to adhere to Current Good Manufacturing Practices (CGMP) to ensure product safety, efficacy, and quality. Ophthalmic drugs contract manufacturers invest heavily in approvals, certifications, and manufacturing facilities upgradation to meet evolving regulatory guidelines. They focus on establishing robust quality management systems, validation protocols, change control systems, and document controls. Regular product quality reviews and internal audits also help contract manufacturers deliver regulatory compliance.
Leading Technology And Specialized Equipment
Ophthalmic drugs require highly sophisticated and precise manufacturing technologies and equipment due to small volumes and concentrations. Contract manufacturers leverage leading technologies like microprocessing, microfluidics, micro-molding, and precision coating to produce a diverse range of ophthalmic products. They invest in specialized, high-end equipment like micronizing mills, soft-gel encapsulation systems, and laser-marking machines. Automation and digitization using IoT, AI, and analytics also help boost production efficiency and quality. The technologies and equipment enable contract manufacturers to cater to customized packaging and dosing requirements of ophthalmic drugs.
Specialized Facilities And Cleanrooms 
Ophthalmic products demand stringent environmental control and hygiene standards owing to small dosage forms and direct exposure to eyes. Contract manufacturers operate highly specialized facilities with ISO classified cleanrooms to minimize microbial and particulate contaminations. Features like laminar air flow, differential air pressures, high-efficiency particulate air (HEPA) filtration help maintain critical environmental conditions. Periodic qualification and calibration of facilities and utility systems also ensure process validation. Designated areas for raw material receipts, products manufacturing, quality testing, packaging, and warehousing follow zoning principles. These specialized facilities enable contract manufacturers to ensure sterility, stability, and preserved efficacy of Ophthalmic Drugs Contract Manufacturing and storage.
Capabilities In Sterile Fill/Finish
A major portion of ophthalmic drugs require sterile fill/finish due to direct administration into eyes. Contract manufacturers have dedicated sterile suites equipped with barrier isolators, aseptic processing equipment, and self-contained environmental control systems. Technologies like lyophilization and terminal sterilization aid microbial decontamination. Stringent personnel training on garbing and cross-transfer procedures helps avoid contamination risks. Regular media fills and endotoxin challenge simulations validate sterilization process efficacy. Quality control testing through rapid microbiological methods, particulate testing and endotoxin assays ensure sterility assurance of aseptically filled ophthalmic products. These capabilities enable outsourcing of sterile fill/finish operations for preservative-free ophthalmic drugs.
Specialized Analytical Testing 
Ophthalmic drugs require meticulous analytical characterization and quality testing due to small amounts administered near eye region. Contract manufacturers invest in -leading analytical instruments like HPLC, GC, dissolution testing equipment, and particle size analyzers. Methods involve testing of identity, purity, content uniformity, particulate matters, pH, osmolarity, sterility, bacterial endotoxin, and preservative content. Stability indicating methods help real-time product monitoring on storage. Various ophthalmic dosage forms like ointments, gels, suspensions etc. also require formulations development and evaluation of rheological properties, spreadability and bioavailability. Contract testing laboratories employ highly trained analytical experts, validated methods and computerized data integrity systems. These specialized testing capabilities help ensure efficacy and safety of outsourced ophthalmic products.
Case Studies And Fill-Finish Agreement 
A leading UK-based ophthalmic drug firm outsourced development and fill-finish operations of its novel anti-inflammatory eye drop to a US-based contract manufacturer. Impressed by proven sterile fill/finish capabilities, quality systems, and regulatory compliance track record, six-month technology transfer was completed on schedule. Further, a 1-year commercial supply agreement was signed with production scale-up clauses. Another Ophthalmic Drugs Contract Manufacturing giant outsourced manufacturing of its portable multi-dose ophthalmic dispensers to a reputed Japanese contract manufacturer specializing in medical-device moulding. Leveraging expertise in micro-molding and precision assembly, the firm ensured precise dosing and improved patients' compliance. These cases illustrate effective collaborations aiding faster access of critical ophthalmic therapies. 
Get more insights on this topic: https://www.trendingwebwire.com/ophthalmic-drugs-contract-manufacturing-meeting-global-ophthalmic-medications-demands-through-specialized-services/
About Author:
Priya Pandey is a dynamic and passionate editor with over three years of expertise in content editing and proofreading. Holding a bachelor's degree in biotechnology, Priya has a knack for making the content engaging. Her diverse portfolio includes editing documents across different industries, including food and beverages, information and technology, healthcare, chemical and materials, etc. Priya's meticulous attention to detail and commitment to excellence make her an invaluable asset in the world of content creation and refinement. (LinkedIn - https://www.linkedin.com/in/priya-pandey-8417a8173/)
*Note: 1. Source: Coherent Market Insights, Public sources, Desk research 2. We have leveraged AI tools to mine information and compile it
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blackvahana ¡ 2 months ago
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reminder to self to eventually write on the coning of the term heaven (counrable noun) as distinct from realm, specifically an astral realm built to house gods. The way he described it was effectively like a software that runs well, but the hardware also supports someone walking physically through it as it's a miniature city in and of itself, with all the subsystems of sewerage and electric and so on. The way it exists is particularly intense but the mental image is of one of those rope things in a jungle gym where you can fall down it and at all layers it's supported by matrices of rope
The main thing is that a heaven is created from and supported by these ropes of big, heavy archetypal forces - it is to environments like a gods body is to a non-gods body. ANVD is going down the road of being a heaven in that it's supposed to be a house for gods, and specifically that conversation came about with the planets getting involved, those are.... heavy expressions of me and those I'm an incarnation with as well as being old and heavy divine forces - they are divine in that they blur the lines between personhood, externality, Consciousness, matter, and so on like aspects of gods do
Whether I succeed in making ANVD like this is besides the point, it's just an example: a heaven is a place that, again, is to an environment what a god is to a nongod, specifically it's lucid in many layers and has the underlying infrastructure to support god manifestation in its flesh. It's not that it just has backrooms that God's can spill into, or at least that's not what ANVD is drifting towards, it's that its flesh itself is capable of holding the consciousness.
It's ultimately a little bit more complicated than "it can withstand a god"? It's ultimately more so about the fact that gods are more present in underlying parts of reality that don't often get built up by those making realms, the behind the scenes type existence of gods fries the system. That's probably Lev's computer metaphor - a nongod can exist in a simulated mmo on a pc but will glitch the game out and fry the pc itself if present. Likewise, realms as opposed to heaven (realms, realms is still an umbrella term I'm just using it like this for now) can support those who don't exist with claws dug into the coding and logic of the realm itself as well as all the elemental things involved in it from fate to time to Mind to whatever else
It's not that heavens are just better realms either in case that seems like the implication, it's not that normal realms lack functions of heavens and that's the only difference. But now I'm sort of like... Oh right. I was trying to remember without realising I was trying to remember what exactly the afterlife and big realms were doing...
Reminder is still a thing because I'm sure I could describe this way better in the future when it's not 1am and I'm not half here
#Heavens specifically being... It's complicated actually. It's complicated#I'm not keeping blogs updated with work on ANVD which makes it more difficult. I am continuing to be very instinctively guarded about this#Not in the way I need to be it's very literally the ''touch my eggs I'll kill you'' instinct lmfao#Anyway. Wording may change but... As I said I was wondering what the difference is. Actually I've been wondering a lot of questions#And that... that crux: that heavens are to environments what god bodies are to non god bodies. That's it#There's an instinctive lived in knowing and ability to logic and create oneself in bodies god or not. Specifically gods have more opened#instincts as I'm defining god at the minute where the god is more conscious and developed I guess than the non god in terms of#all the extraneous bodies and all the spacetime selves and the powers and aspects and so on. It's the nature of Being where#something self-perpetuates and knows what it is as it has a core gravity - heavens have a core gravity and selfhood that expands like a god#does. Because non self realms are just mental realms. When the realm itself is self sustaining and anchored to various things - feeding and#producing a self and a body and so on - and that self is god-like but the environmental version of god-like. Yeah#À heaven I guess can be programmed and less self-created than this implies which is to say ANVD is very borderline a person#and I get that colours my vision of realms uh. But either way. If it's able to maintain it's own body and the body spreads into what gods#spread into and it maintains a reality and a self and a body on these levels and can house gods that's a heaven. Essentially.#ramblings //#Realms //#Im not sure about my descriptions here though I think I need to go read up on a bunch of stuff. There's something really fucking#weird in my mind in between me and realms. Like a cork on a bottle of wine. Right. Time to go drink with lev#But honestly I am something that is in a bottle and I keep trying to formulate thoughts on what realms are and something#stops me. I don't know what. Probably Black because this is what happens when I try to investigate things he doesn't want me sniffing
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neverendingford ¡ 2 months ago
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