#drug absorption

[curiousquill1]

Science Behind Spheronization: Why Shape Matters in Pharmaceutical Production

The pharmaceutical manufacturing world is pretty complex. The size of the particles is one prime consideration that can make a world of difference in achieving quality and effective medicines. At the core of it lies spheronization—the process of converting raw material into uniform spherical particles in order to improve the production efficiency and performance of the final drug product.

Awareness: Spheronization and Its Implication in the Pharmaceutical Industry

Spheronization refers to an advanced pelletizing technique that results in creating nearly round particles from a powder, granules, or other forms of solid. One can even control the process of production by changing the process variable inside a spheronizer. The size distribution is narrow and specific to formulation requirements for spherical particles resulting from the spheronizer.

So why does this round shape make so much difference in pharmaceutical? This is basically because the physical properties are unique which the spherical particle possesses. Compared with irregular particles, the spherical particle has the flowability feature. For this reason, it could easily feed to the equipment smoothly and with consistency—the tableting equipment, and the encapsulation equipment for that matter. It can be compressed to a considerable pressure, hence making sturdy, excellent tablets, capsules, and so forth.

Ultimately, the spherical shape unlocks major benefits through the entire pipeline of pharmaceutical production, from streamlining manufacturing processes to improving quality and performance of the final drug product. That is why spheronization has become an indispensable tool in the modern pharmaceutical industry.

Consideration: Technical Advantages of Spherical Particles

The very simple yet highly creative process on which lies the heart of spheronization involves taking pharmaceutical powders or granules and introducing them to the particular equipment like the spheronizer. Once this is done, a controlled rotation, coupled with friction, ensues, and the smooth agitation makes the particles turn into almost perfect spheres because of a gradual process of forming rounded shapes.

There are many technical advantages of the spherical shape per se. First, an ideally uniform particle size as well as a relatively smooth surface renders spheres better flow and handling properties which are really of great importance for assured dosing that is reproducible in the process of tabletting, encapsulation, or other types of filling operations. This sort of fluidity allows fewer stops of machinery, decreased scrap, and therefore generally increased output.

However, the advantages of spheronization go far beyond making a production process easier. The round shape also plays a very important role in performance and stability of the drug product in the end. Spherical particles are usually characterized by more favorable dissolution profiles and have drug release kinetics that are predictable and reproducible. Further, the size and distribution of spheronized particle sizes may also stabilize the physical properties of formulation, reducing the possibility of segregation or caking over time during storage and shipping.

Conclusion: Practical Applications of Spheronization Technology

The versatility of spheronization technology makes it a valuable tool for a range of pharmaceutical applications. The ability to produce high-quality, spherical particles is one of the key enablers for manufacturers looking to provide effective and reliable drug products for patients—from immediate-release tablets to controlled-release beads.

Another excellent use of spheronization is in multiparticulate drug delivery systems. Uniform spherical pellets or minitablets formed with the help of a dedicated spheronizer allow the formulator to design complex release profiles suitable for the particular physiological requirements of the patient. This precision, as one might expect, is directly translatable into improved clinical performance and patient experience.

There are many other applications where it extends far beyond the drug. Thus, manufacturing fertilizers produce spherical granules, which can improve spreading while reducing dust and will be efficient to apply without creating hazards on workers' safety. For the sphere in ceramics or abrasives, it would increase polishing performance and lessen the amount of wear of the machines.

By passage of time, its importance will continue to augment amongst the pharmaceutical industries about this spheronization technology. Through the application of principles and scientific knowledge for developing uniform, spherical particles to manufacture through a specialized machine that reduces the production line's steps and increases product quality in a final healthcare delivery line that benefits patient well-being.

In situ, raw materials are to be shaped into uniform performing particles—a vital part of the contemporary pharmaceutical arsenal with more complex drug formulations bringing a demand for improvement and spheronization. Total control by pharmaceutical companies in the science behind such a process will unlock new dimensions that can further efficiency, quality, and innovation—all within improved safety and efficacy for patients in medical treatments.

[calibraptor]

When news came out that the hydroponics department was passing out some premium green, I got an invitation to 'come over and have some edibles'.

Naturally upon actually showing up I assume the gaggle of stoned individuals before me are the edibles and start cramming them one by one into my craw!

Then, as my stomach goes to work softening and absorbing the clutch of stoners cradled in me, I decide to try a puff of that discarded dart! Naturally, never having smoked before, I end up nearly hacking my lungs up.

As my stomach recedes back against my core and my 'edibles' are fully assimilated, I start to feel fuzzy. REALLY fuzzy. I'm probably resilient enough to handle one edible, but four?! Nope, nuh uh, I'm done, utterly giga-blazed.

The friend residing on my belly just seems happy to be there.

The two filling out my haunches seem to be giggling and snickering at how LOST IN THE SAUCE I am.

The one on my tail? Uhh, well it seems like he's figured out how to take control of my tailmaw and is now cackling like a disney villian in the back of my head and making plans to add more people to the squishable collective already clinging to my body.

Pretty sure I'm too brain blasted to stop him, and soon enough the munchies will make it so I won't want to!

Art by HipHopDingo on Furaffinity

[unohanadaydreams]

With Mayuri's predilection for psychedelics and undermining his opponents, I think the Pernida fight would've been so cool with mushrooms.

Like.

Mayuri messing around with rate of decomposition of a mushroom to counteract Pernida's physical drawing of reishi which he would've started formulating from his extensive knowledge of Quincies reishi absorbing abilities before he necessarily knew Pernida was doing so physically. And better yet, using a certain mushroom to basically treat Pernida like a big old cancer growth. (Like, cue big, wide smile as Mayuri reveals the reishi that Pernida has been absorbing is the reason his advancement is halting. Because he would use that mushroom JUST to say that)

I don't feel he would need to win and would love to see him lose, but I think it just would've been even more fun--for me--and crushing--for Mayuri <3-- if he would've actually applied his exhaustive knowledge of quincy to the Pernida battle if only because he was under the assumption that he would be exclusively fighting quincy in the big quincy war. Don't even think he needs to recognize Pernida as a quincy early on even!

Honestly, appalling that Mayuri doesn't have more canon dabbling with mushrooms. Like using altered cordyceps in his fight with the zombies?? Creating a horrible malformation of a coffin mushroom that decomposes Giselle's zombies in 3 minutes rather than 3 years...................AH.

I feel like it would've fit TYBW more than the weird fantasy thyroid thing that hardly made sense and had me squinting for 15 minutes trying to cobble together even that vague description--fantasy thyroid thing--when reading descriptions of how Mayuri was using Nemu to beat Pernida and reviving Hitsugaya & Matsumoto.

Also, he would still get to make people trip balls and question their sanity, which is part of his pyramid of fulfillment.

ALSO roots and spores are very convenient when trying to bullshit that Mayuri was actually doing something All Along when he definitely was not.

[mini-uzzy]

phamacist info dump in the tags :

i know vitamin c basically neutralizes adhd meds but lemonade good

[lifechangingtips]

Understanding Anti-Obesity Medications: A Comprehensive Guide

Exploring the Mechanism of Anti-obesity medications: A Comprehensive Guide Understanding the mechanism of anti-obesity medications can seem like a daunting task, but it doesn’t have to be. Let’s break it down in a way that’s easy to digest, no pun intended. If you want more information about diet, please visit my website! Here Understanding Anti-Obesity Medications: A Comprehensive…

[harmeet-saggi]

Winning The Battle Against Obesity: The Role Of Obesity Drugs

Greetings, health-conscious readers! Today, we're delving into a topic that impacts millions worldwide – the ongoing fight against obesity. This topic is close to our hearts because, after all, who doesn't aspire to live a healthy life? In this article, we'll explore the dynamic and ever-evolving world of obesity drugs. We'll discuss the challenges, breakthroughs, and all you need to know about these vital tools in the fight against excess weight. 

Know more

[ahopefulbromantic]

Hello Mouthwashing enjoyers, a doctor here

So i finally played the game yesterday and noticed a detail that isn't talked about enough:

10 mg oxycodone for someone in Curly's condition wouldn't do jack as a painkiller. From what i understood, he also takes it only once a day orally. When he's easily at the very top of the analgesic ladder (meaning due to his state he would need the strongest narcotics in the highest doses, preferably intravenously). Especially that 1) idk about the state of his digestive tract but i can venture to say the absorption would be very poor (meaning a big portion of the drug would just pass through his guts without actually going into the body), and 2) he's been taking it for months and oxycodone as an opioid builds tolerance (meaning his organism "gets used to" the drug and gradually needs more for the same effect). He probably feels that himself, that's why he's reluctant to take it throughout the game.

But don't worry, it gets worse!

Because later on, when we find out we're out of meds and find a hidden stash, it turns out to be...

500 mg paracetamol. As in, half a dose you yourself would take for a headache on a good day. It's placebo at best. What's even the point.

So yeah, if any of you playing thought something along the lines of "it's horrible i hate it i hate giving meds to Curly but at least the painkillers make him feel better" No. They don't. They never did. He may moan less but he's not in any less pain. I'm sorry.

[wellhealthhub]

Diabetes Medication for Weight Loss: An Effective Approach to Manage Diabetes and Shed Pounds

Unearth the profound potential of diabetes medication in facilitating weight loss endeavors. Embark on an enlightening journey to grasp the multifarious types of antidiabetic drugs, discern their intricate mechanisms of action, and appreciate the paramount significance of personalized approaches to treatment. Discover a plethora of answers to frequently asked questions, coupled with comprehensive…

[iconhub2023]

Lipid Control Plus Cholesterol

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[literaryvein-reblogs]

Writing Notes: Poison

References (Forms, Actions & Examples of Poison; Route of Administration; Some Symptoms; What to do if a Poisoning Happens)

400 years back, Paracelsus stated that, “All substances are poisons; there is none which is not a poison.”

If the right dose is taken, it could become a remedy, otherwise poisonous.

Poison - a substance which when administered, inhaled or swallowed by living organism causes ill effects on the body. It is defined also as a medicine in a toxic dose. Toxic substance may be solid, liquid, gas or any environmental agent.

Forms of Poison

Physical form: Gaseous/volatile/vaporous forms of poisons act faster than liquid poisons as they are quickly absorbed. Similarly, liquid poisons act faster than solid poisons. Gaseous or volatile > liquid > solid. For solid poisons, powdered poisons act quickly than the lumps. For example, there are certain seeds that escape the gastrointestinal tract as they are solid, but when crushed, they can be fatal. For solids: powdered > lumps

Chemical form: Few substances like mercury or arsenic are not poisonous as they are insoluble and cannot be absorbed when they are in combination with other substances like mercuric chloride, arsenic oxide, etc. In other cases, the action is vice versa. For example, there are some substances that become inert in combination with silver nitrate and hydrochloric acid and are deadly and poisonous when present in pure forms.

Mechanical combination: The effect of poisons is significantly altered when they are combined with inert substances.

Action of Poisons

Local action: Direct action on the affected site of the body. Examples include irritation and inflammation in strong mineral acids and alkalis, congestion and inflammation by irritants, the effect on motor and sensory nerves, etc.

Remote action: Affects the person due to absorption of that poison into the system of that person. For example, alcohol is absorbed in the system and then it affects the person.

Local and remote actions: Some poisons can affect both local and remote organs. Thus, they not only affect the area with contact to the poison but also cause toxic effect after absorption into the system.

General action: The absorbed poison affects more than one system of the body, for example, mercury, arsenic, etc.

Route of Administration

The route of administration is the path through which a drug, toxin, or poison is taken or administered into the body of a person which is distinguished by the location where any drug is applied. It is mostly classified on the basis of its target:

Topical—has a local effect

Enteral—has a wide effect, i.e., affect the whole system

Parental—follows a systemic action

Poisons are given or taken so that death can occur at once by shock due to stoppage of body’s vital systems.

Route of administration plays a very important role in determination of death by poison as time in which death occurs are fastest in inhaled poisons, relatively slow in injected and lastly when ingested orally.

Some Symptoms

Sore throat

Trouble breathing

Drowsiness, irritability, or jumpiness

Nausea, vomiting, or stomach pain without fever

Lip or mouth burns or blisters

Unusual drooling

Strange odors on breath

Unusual stains on clothing

Seizures or unconsciousness

Examples

Poisons Based on Mode of Action

1. Corrosive poisons

Strong Acid - sulfuric acid, nitric acid, hydrochloric acid

Strong Base - sodium hydroxide, potassium hydroxide, ammoniumhydroxide

2. Irritant poisons

(a) Inorganic:

Metallic - lead, arsenic, mercury, antimony, copper, zinc

Non-metallic - chlorine, bromine, iodine

(b) Organic:

Vegetable - croton oil, castor oil

Animal - snake venom, scorpion venom, spider venom

(c) Mechanical: powder glass, diamond dust

3. Neurotic poisons

Cerebral - alcohol, opium, barbiturates, benzodiazepines

Spinal - strychnine

Peripheral - curare

4. Cardiac poisons

5. Asphyxiants - CO2, CO

Poisons Based on Medicolegal Classification

Homicidal poisons - aconite, abrus precatorius, strychnos nux vomica

Suicidal poisons - opium, barbiturate, organophosphorous, organochloro compounds

Accidental poisons - snake bite, CO, dhatura's seeds as it resembles capsicum seeds

Abortifacient poisons - quinine, calotropis

Stupefying agents - dhatura, chloral hydrate

Agents used to cause body injury - corrosive acids

Cattle poison - abrus precatorius, calotropis

Used for malingering - semicarpus anacardium

Poisons Based on Toxico-analytical Classification

1. Gaseous poisons: methanol, ethanol, benzene, toluene, acetone

2. Volatile substances: ethane, butane

3. Organic Non-volatile substances:

Drugs - opiates and synthetic narcotics, sedatives and hypnotics, stimulants, depressants

Pesticides - insecticides, fungicides, herbicides, rodenticides, nematocides

4. Metallic poisons: arsenic, lead, mercury, antimony, zinc, copper

5. Anion poisons: bromide, cyanide, fluoride, hypochlorite, nitrate, phosphate, sulfide, sulfate

Poisons Based on Physical State

1. Solid: lead, arsenic, mercury

2. Liquid:

Organic - ethanol, methanol, chloroform, acetone

Inorganic - liquid ammonia, liquid sulfur dioxide

3. Gaseous: carbon dioxide, carbon monoxide

Poisonous Fumes or Gases

In the home, poisonous fumes can be emitted from the following sources:

A car running in a closed garage

Leaky gas vents

Wood, coal, or kerosene stoves that are not working properly

Mixing bleach and ammonia together while cleaning, which makes chloramine gas

Strong fumes from other cleaners and solvents

Common Household Products

Oily hydrocarbon products are thin and slippery and can easily suffocate if the substances are drawn into the lungs when ingested. The products can cause chemical pneumonia by coating the inside of the lungs. Products that are required to have a safety lid include:

Baby oils

Sunscreens

Nail enamel dryers

Hair oils

Bath, body, and massage oils

Makeup removers

Some automotive chemicals (gasoline additives, fuel injection cleaners, and carburetor cleaners)

Cleaning solvents (wood oil cleaners, metal cleaners, spot removers, and adhesive removers)

Some water repellents containing mineral spirits used for decks, shoes, and sports equipment

General-use household oil

Gun-cleaning solvents containing kerosene

Oil products that are thicker and more "syrupy" are not as problematic, since they are not as easily inhaled into the lungs.

What to do if a poisoning happens

Swallowed poisons

Stay calm, act quickly, and follow these guidelines:

Get the poison away

If the substance is still in the mouth, make them spit it out or remove it with your fingers (keep this along with any other evidence of what was swallowed)

Do not make them vomit

Do not follow instructions on packaging regarding poisoning because these are often outdated. Instead, call Poison Help to get connected to a local poison center.

Take or send the poison container with you to help the healthcare provider find out what was swallowed.

Poisons on the skin

If someone spills a chemical on his or her body, remove his or her clothes and rinse the skin with lukewarm—not hot—water.

If the area shows signs of being burned, continue rinsing for at least 15 minutes, no matter how much they may protest.

Then call the poison control center for further advice.

Do not use ointments or grease.

Poison in the eye

Flush the eye by holding the eyelid open and pouring a steady stream of lukewarm—not hot—water into the inner corner of the eye.

If this is a child, you may need help from another adult to hold the child while you rinse the eye.

Continue flushing the eye for 15 minutes, and call the poison control center for further instructions.

Do not use an eyecup, eyedrops, or ointment unless the poison center tells you to do so.

Poisonous fumes or gases

If someone breathes in fumes or gases, get him or her into fresh air right away.

If they are breathing without a problem, call the poison center for further instructions.

If they are having difficulty breathing, call 911 or your local emergency service (EMS).

If they have stopped breathing, start CPR and do not stop until they breathe on their own or someone else can take over.

If you can, have someone call 911 right away.

If you are alone, perform CPR for 2 minutes and then call 911.

Be prepared for a poisoning emergency by posting the poison center telephone number by every telephone in your home.

Sources: 1 2 3 ⚜ Writing Notes & References

Writing Notes: Fictional Poisons

[metalheadsforblacklivesmatter]

For the love of the gods. STOP SAYING "CHECK MEDICATION INTERACTIONS" ON MY ACTIVATED CHARCOAL POSTS.

This is what it said if I "check drug interactions" between ibuprofen (a common pain medication) and activated charcoal.

You see how it says "no drug interaction"?

This is what I get when I look up scholarly articles on the effects of activated charcoal.

You see where it says "Activated charcoal will block the absorption"?

Because there's a difference between "that's what activated charcoal does" and "drug interaction".

You're not gonna experience any ill effects of the "drug interaction" You're gonna experience the effects of your chronic pain and other disabilities because activated charcoal makes your meds not work.

-fae

[lonelynpc]

Medical Inaccuracies I Commonly See In Fics

the titanium skull: characters getting hit on the head and just walking it off or having no repercussions.

swiss army doctor: this doctor knows everything about every specialty. bow before them.

that's my son!: a medical professional treats a loved one.

no nurses needed: the doctor does everything.

companionless, powerful, resolute (CPR): a character does CPR for more than 2 minutes without getting fatigued or swapping out without compromising the quality of their compressions.

shocking asystole: it is simply not a shockable rhythm. please, stop shocking asystole.

'tis but a scratch: a character coughs up or vomits blood but then is fine. also when someone gets shot or stabbed in the hand, leg or shoulder with no lasting impacts.

sims pregnancy: character takes a test the morning after and it's positive.

a refreshing nap: comatose patients waking up and moving around immediately.

neck needles: a character injects something into someone's neck with ease, i guess their neck veins are just magnetised or something.

zap zap: electrocution with no burns, entry or exit, nerve or cardiac damage, dislocations, etc. did you know one of the causes of the less common posterior shoulder dislocation is electrocution?

i don't need this anymore: character gets stabbed and pulls. out. the. blade. to no ill effect.

tourniquets, tourniquets and more tourniquets: a character is bleeding? oh no, time to grab the TQ.

calm, level-headed, tranquil: this character is such a seasoned professional that they don't get an adrenaline rush anymore.

one-way ticket to the afterlife please: character uses a medication or treatment that would do the opposite of treating their condition but it works somehow. (hypoglycaemic patient uses insulin for example)

bumper cars: character is in a major car accident and just walks away with minor injuries.

here's all that confidential information you ordered: character asks for an update on an injured or sick character and the staff just give them the information without consent.

instant absorption: character is given a drug and it works immediately.

[againstme]

idk man i’m just thinking about against me! and transness, especially cause we’re coming up on ten fucking years of transgender dysphoria blues, on the 21st.

lyrics have been swimming in my head lately.

“what god doesnt give to you, you’ve got to go and get for yourself.”

“if i could’ve chosen, i would’ve been born a woman. my mother once told me she would’ve named me laura. i’d grow up to be strong and beautiful like her.”

“you wouldn’t think something like gender identity would complicate something like asking for some company.”

“she spent the last few years of her life running from the boy she used to be.”

“standing naked in front of that hotel bathroom mirror, in her dysphoria’s reflection, she still saw her mother’s son.”

“agitated states of amazement, never quite the woman that she wanted to be.”

“you want them to see you like they see every other girl, they just see a faggot, they hold their breath not to catch the sick.”

“chipped nail polish and a barbed wire dress. is your mother proud of your eyelashes? silicone chest, and collagen lips. how would you even recognize me?”

“no more troubled sleep, there’s a brave new world that’s raging inside of me.”

“all my life, wishing i was one of them. there will always be a difference between me and you.”

“what’s the best end you can hope for? pity fucks and table scraps?”

“all the young graves filled, don’t the best all burn out so bright and so fast?”

“sometimes at night, i pray to wake a different person in a different place.”

“i don’t want to hang around the graveyard, waiting for something dead to come back. i know you think you’ve got one up on me, that you can see something i can’t.”

“i wanna be so real, you can see the difference.”

“dig up your bones, early graves are not homes.”

“come on, shape shift with me! what’ve you got to lose? fuck it!”

“confessing childhood secrets of dressing up in women’s clothes, compulsions you never knew the reasons to.”

“i’m sick of feeling like i’m losing my mind. sick of doing the same things most nights after night. sick of self loathing and self absorption, self destructive narcissism.”

some of these are directly referencing transness, some just alluding to it. some are just ones that i relate to as i’ve grown up struggling with my gender and sexuality and accepting my own transness and dealing with self harm and self destruction and relying too much on drugs.

finding myself buying baggies of coke and just stuffing them in my wallet while i walked downtown, feeling this immense guilt at the bottom of my stomach for essentially just wasting 25 dollars on a drug that wasn’t doing much for me besides making me feel like i was feeling something different than what my life was. getting scared shitless while in the line at the convenience store after picking up, seeing cops come into the store, and the small tied up bag filled with what was more baby powder than coke in my back pocket felt like the the heaviest and most obvious thing in the world.

and then i’d find myself on calls with my friends, with my camera turned off or pointing at the ceiling, suddenly muting my mic holding a cut up piece of a straw in my teeth as i crushed shit up with my library card from a city i wasn’t planning on living in again. just having them talk while i was racking baby lines, tilting my head back and rubbing it on my gums after. i was sniffling all the time. sometimes my nose would bleed when i would wake up. and i wasn’t even really feeling much; i didn’t know at the time that this would be because of having adhd and just basically spending money on overpriced shit that was just like taking an adderall, but it was a drug in front of me, that gave me the idea or the false hope of running away from my life during the short lived high.

“before you know it, here i am again, fucking 6 o’clock in the morning, rolled up dollar bill in my hand.”

“what the fuck are you cutting this with, anyway?”

“how low can you go before you can’t turn around?”

i don’t think that when i was 14 and getting into against me! that i would ever actually get to a point of fully relating to those lyrics. of running away from such a huge part of yourself or your problems, trying to fill the void with drugs that you’d plow through so quickly, faster than you thought you would every time.

the thing is, was that at this point, i had already started my transition. i was already “passing.” but i never got to the root of it. sure, i’m trans, but who am i? and i didn’t know how to answer that question. so i just pushed it away, pushed it under the rug.

“you can pray all night and day, but you’ll still wake up the same person in the same fucking place.”

against me! has been there for me for ten years. throughout so many transformations of myself, so much shape shifting, so much dysphoria, so many late nights wishing i was a different person in a different place.

i found solace in their lyrics. it gave me some small bit of hope, some realization that i didn’t know that i needed; that trans people always have been and always will be here, that being able to be trans and be alive is possible, and that i don’t have to be digging my own grave, spending late nights staring at the mirror and seeing the girl who i used to be.

against me! gave me the courage to be alive.

[gay-jewish-bucky]

IMPORTANT PSA

As we approach spooky season and you start seeing food coloured black, remember that foods with activated charcoal can be very dangerous if you take medications, because it reduces or completely counteracts the absorption of prescription drugs into your system, this is why it's commonly used in the medical field to counteract orally ingested poisons.

[lifechangingtips]

Understanding Anti-Obesity Medications: What You Need to Know

Exploring the Efficacy of Anti-Obesity Medications: A Comprehensive Guide Anti-Obesity Medications: Understanding Their Role in Weight Loss Introduction Obesity is a significant global health concern that can lead to chronic conditions such as diabetes, heart disease, and certain cancers. For many, lifestyle changes like diet and exercise are the first steps in managing obesity. However, some…

[j2h5b5]

It didn’t take a genius to realize that Steve Harrington was devoted to his kids.

And they were indeed Steve’s kids. He knew it, they knew it, anyone who saw him with them knew it, including, oddly enough, the children’s actual parents. They might not have understood exactly why their offspring were so tightly intertwined—with each other and with Steve and with the small assemblage of Hawkinsians that included the chatty and rather eccentric girl who worked with Steve at the local video store, a straight-laced honor student turned journalist who had recently taken up a distinct interest in (and displayed an alarming talent for) deadly weaponry, the lead singer of a heavy metal band who was also known to be a petty drug dealer, and, perhaps most baffling of all, the former police chief.

The biological parents might not have known why, but they knew that these people made up their kids’ other family—their Chosen Family, as it were. And not a single one of them—for reasons rooted in either blissful ignorance, parental inadequacy, self-absorption, or just relief that someone else was handling the hard stuff—was about to interfere in that.