#death cell
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fisherrprince · 3 months ago
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dummy trio let’s go ‼️‼️
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if-you-fan-a-fire · 3 years ago
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“SLAYER OF FATHER SENTENCED TO HANG,” Montreal Star. November 11, 1931. Page 28. ---- BARRIE, Ont., Nov. 11. - (C. P.) - Thomas Wesley Campbell, 56, of Alliston, recently convicted of the murder of his father, was last night sentenced by Mr. Justice Jeffrey to hang on January 16 next. An Assize Court jury returned a verdict of guilty at the trial of Campbell two weeks ago for the death of his father. William Campbell, 82-year-old retired farmer of Alliston.
Campbell heard the death sentence without any visible sign of emotion. Then he was led into solitary confinement in the death cell at the county jail here.
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cheetyuwu · 2 months ago
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blabberoo · 7 months ago
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:")
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reasonsforhope · 2 days ago
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"A study looking at the bearers of artificial hearts found that a subset of them can regenerate heart muscle tissue—the first time such an observation has ever been made.
It may open the door to new ways to treat and perhaps someday cure heart failure, the deadliest non-communicable disease on Earth. The results were published in the journal Circulation.
A team of physician-scientists at the University of Arizona’s Heart Center in Tucson led a collaboration of international experts to investigate whether heart muscles can regenerate.
According to the Centers for Disease Control and Prevention, heart failure affects nearly 7 million US adults and is responsible for 14% of deaths per year. There is no cure for heart failure, though medications can slow its progression. The only treatment for advanced heart failure, other than a transplant, is a pump replacement through an artificial heart, called a left ventricular assist device, which can help the heart pump blood.
“Skeletal muscle has a significant ability to regenerate after injury. If you’re playing soccer and you tear a muscle, you need to rest it, and it heals,” said Hesham Sadek, director of the University’s Sarver Heart Center.
It was previously thought that when a heart muscle is injured, it could never grow back.
“Irrefutable evidence of heart muscle regeneration has never been shown before in humans,” he said. “This study provided direct evidence.”
The project began with tissue from artificial heart patients provided by colleagues at the University of Utah Health and School of Medicine led by Stavros Drakos, MD, PhD, and a pioneer in left ventricular assist device-mediated recovery.
Teams in Sweden and Germany used their innovative method of carbon dating human heart tissue to track whether these samples contained newly generated cells. The investigators found that patients with artificial hearts regenerated muscle cells at more than six times the rate of healthy hearts.
“This is the strongest evidence we have, so far, that human heart muscle cells can actually regenerate, which really is exciting, because it solidifies the notion that there is an intrinsic capacity of the human heart to regenerate,” Sadek said.
“It also strongly supports the hypothesis that the inability of the heart muscle to ‘rest’ is a major driver of the heart’s lost ability to regenerate shortly after birth. It may be possible to target the molecular pathways involved in cell division to enhance the heart’s ability to regenerate.”
In 2011, Sadek published a paper in Science showing that while heart muscle cells actively divide in utero, they stop dividing shortly after birth to devote their energy to pumping blood through the body nonstop, with no time for breaks.
In 2014, he published evidence of cell division in patients with artificial hearts, hinting that their heart muscle cells might have been regenerating because they were able to rest.
These findings, combined with other research teams’ observations that some artificial heart patients could have their devices removed after experiencing a reversal of symptoms, led him to wonder if the artificial heart provides cardiac muscles the equivalent of bed rest like a person needs when recovering from injury.
“The pump pushes blood into the aorta, bypassing the heart,” he said. “The heart is essentially resting.”
Sadek’s previous studies indicated that this rest might be beneficial for the heart muscle cells, but he needed to design an experiment to determine whether patients with artificial hearts were actually regenerating muscles.
Next, Sadek wants to figure out why only about 25% of patients are “responders” to artificial hearts, meaning that their cardiac muscle regenerates.
“It’s not clear why some patients respond and some don’t, but it’s very clear that the ones who respond have the ability to regenerate heart muscle,” he said. “The exciting part now is to determine how we can make everyone a responder, because if you can, you can essentially cure heart failure.
“The beauty of this is that a mechanical heart is not a therapy we hope to deliver to our patients in the future—these devices are tried and true, and we’ve been using them for years.”"
-via Good News Network, December 31, 2024
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mutable-manifestation · 2 months ago
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Ghost Chirps AU Part 5
Part 1 & 2
Part 3
Part 4
***
While “Jason” (i.e. Alfred with an empty jet that Jason will meet up with later in order to “arrive” in Amity) hops a private jet, Red Hood is busy searching the Fenton home from top to bottom.
The local police move slowly, and by the time they arrive Jack and Maddie Fenton are both tied up and disarmed in their living room under heavy guard.
They hadn’t been restrained immediately, Batman talking him into giving them a chance to implicate themselves first.
Hood let him take the lead, but he didn’t even get a chance to ask a question, being cut off at the first indication he might want to talk about their “work.” Less than 60 seconds in, and the pair had outright confessed to violating the meta protection acts - and in tedious detail.
The questioning didn’t suffer any from them being tied up.
Far from the mulish silence or crocodile-tear laden denial of most criminals, they instead doubled down, insisting that nothing they had done was illegal, then jumping to the assumption that they were “possessed” - and boy had it been a nasty surprise when the whole house came alive trying to attack them with a quick verbal command.
Well, trying to attack Hood. And only him, for some reason.
One laser also freed the Fentons, who turned out to have even more weapons built into their suits. 
Somehow. 
Despite them being skintight.
That had been a pain, but Red Robin was able to hack the system using one of the couples’ own devices while Hood dodged - and kept the stray fire away from the others - leaving everyone else to recapture the pair. A blessedly simple task once they found out the lasers would splash harmlessly off of their armor (save for a gross film of green goop left wherever they grazed).
They take turns knocking each unconscious to change them in order to properly disarm them - Batman and Nightwing taking Jack first, followed by Orphan and Spoiler dealing with Maddie. 
The only non-weapon laden clothing they own turns out to be pajamas. 
This is around when the police show up, looking hesitant.
They, too, cite the “Anti-Ecto Acts.”
Oracle had debriefed them on the supposed Acts and “Ghost Investigation Ward” on their short drive over. Both were utterly bogus - the Acts had never even been proposed, let alone been approved as law, and the so-called “GIW” had no ties to the government.
The Fentons had been furious and denied the information intensely when told, but the cops mostly just looked relieved.
Apparently there’d been a lot of property damage by the GIW and Fentons both that had supposedly been dismissed under the Acts as “necessary in the pursuit of ecto-scum.”
For the Fentons, half of this damage was in the form of broken fire hydrants, cracked sidewalks, and totaled cars - they’d never been good drivers, before, the cops disclosed, but they’d become even more negligent since the ghosts began appearing, to the point they had to have a news segment warning when they would be on the road.
The lack of fatalities thus far had been nothing short of a miracle, they claimed.
“Of course there haven’t been any fatalities!” Mrs Fenton defends. “Our work is to protect people from those things, not make more! Officers, listen to reason-” Hood snorts disdainfully -”The Red Hood is clearly a ghost! All our systems targeted him the moment they came online - and they only target ecto-entities. He’s clearly taken these heroes under his sway - why else would they be working with a murderer!? You have to do something before he starts up his killing here in Amity!”
The officers look at him a bit hesitantly, but Batman is unmoved and gives the cover story Hood had outlined back in the alley.
Any concerns the locals have are quickly assuaged.
But for the whole explanation, Jason is trying not to shake even as he falls apart in place.
Their little website called them ghost-hunters, making it pretty clear what “ecto-entities” meant. 
Their system supposedly only targets ecto-entities.
The system had only targeted him.
The system only targets ghosts.
Jason had died.
A lot of his family members had died, too, granted. 
But Jason was the only one who seemed to come back wrong - anger sticking in his throat and never quite fading, an inclination towards violence even when he wasn’t angry well beyond what he’d ever felt before, and a sea of other emotions (that he would never acknowledge aloud) and triggers for those emotions that he always struggled to make heads or tails of.
He doesn’t have the meta gene. He knows that. He knew that.
He just assumed that the test missed it, because he knows he doesn’t know magic - the All Blades being the only exception - and he couldn’t think of another explanation at the time.
But he came back wrong.
And as he stands there, he wonders if he came back at all, mind on Solomon Grundy.
Wonders if he isn’t just some ghost, wandering around possessing his own corpse.
He jolts, as the thought strikes him: what about Danny?
If he’s a ghost and chirping is a ghost thing then what about his KID!?
Absently, he notes that Bruce has started interrogating the cops on what they meant by “ghost attacks.” 
He ignores the discussion, hustling for the door in the kitchen down to the lab.
He slams and locks the door behind him - in Red Robin’s face - as he descends, making a b-line for the computer he’d seen when the Fentons had dragged them all down there to start bragging about their crimes.
The only thing Oracle could get out of the whole building was things that were openly available online; direct connections were impossible.
Opening up the screen, he gets to cracking.
Going for the surface level files first, it turns out he doesn’t even need so much as a password to find what he wants.
One of the video game sub-files has an unrelated file in it: ghost notes.
There are plenty of other notes, of course, but he’d only been skimming to start, looking for anything hidden.
The Fenton parents were too open to bother, of course, with plenty of more obvious files strewn haphazardly across the home screen, but it’s always better to check. That there is a hidden file means it was likely made by either Danny or Jazz.
And it’s a treasure trove.
Sub-files for rogues, allies, conditional allies, and “halfas” were what greeted him.
The last being the only term he didn’t recognize, he clicked.
6 files: Clones, Danny, Dani, Dan, Vlad, and Red Hood.
He clicks his own file.
What greets him is a picture of himself 4 days ago, looking just to the left of the lens in an alley that he distinctly remembers searching for the kid in.
Just below is text.
~~~
??? Name: Red Hood
Species: probably a halfa
Status: Nnnneutral? I think? I know, I know, heads in bags. But Valerie tries to kill me all the time! And we’re allies sometimes! Hood- uh- looked for me? Okay I guess I can’t really judge this yet but please read the first met section before you judge please you guys?
First met: Aug 17, 2005, was in Gotham to bother Batman, stopped to think a bit on some fire escape - decide on the first prank yknow - but then my ghost sense went off. It felt like a halfa so I thought “oh cool, must be Dani” so I chirped, but then Red Hood - who was chasing some guy down an alley at the time - froze and looked around. I dropped visibility and chirped again and yeah, he definitely heard it. Humans can’t so he’s definitely a halfa - no glow so he can’t be a full ghost and it felt nothing like an overshadowing. 
Ended up following Hood around the rest of week - forgot to prank Batman, damn - and playing hide-and-seek with the chirps. It was really funny. But he very obviously doesn’t know he’s a halfa. But the guy is, like, scary levels of smart, so I’m sure he’ll figure it out on his own now that the chirp thing made it clear that something is up. Hopefully.
I figure I can go back in winter break - he should have it figured out and let his emotions process enough by then to at least hear me out when I explain the AEA and GIW and everything, then it won’t matter so much if he can, like, track me by voice or something if I talk since we’ll have MAD by then.
Despite his reputation, the people living in his haunt seem to love the guy. I can see why. On top of the whole smart he’s actually really nice to people he’s not shooting in the knees (which only even happened one time in the week I was there? It was actually pretty relaxing - most quiet week I’ve had since the portal opened THANK YOU TUCKER for hacking the portal hatch to be inoperable for a week). 
Where was I? Oh yeah, he’s actually surprisingly nice to people? So like, I think he’ll probably hear me out if I go back and be polite? I hope. Hate to leave the guy in the dark and him end up on the GIWs dissection table for “lots and lots of painful experiments.”
Not that those guys could even catch the Box Ghost. But uh, Hood doesn’t seem to have powers either? Or if he does he doesn’t know about them I don’t think - he only used the chirp the whole time I was their - not even to cheat with moving around.
Seriously. That guy's acrobatics could make Freakshow’s contortionist green - er, red??? - with envy. Actually wait, aren’t contortionists and acrobats different things?
SAM NOTE: help^?
Powers: 
?
~~~
Jason leans back, breathing deeply.
“Not a full ghost,” “not 'overshadowed'” - a term that sounds likke some kind of cousin to possesision - “definitely a halfa,” “humans can’t hear chirps.”
Halfa. 
Half. 
Ghost. 
Half Ghost.
It should sound absurd - you can’t be half alive and half dead.
But Jason has seen the Lazarus pits, has met Solomon Grundy, has met aliens and bullshit magic and can pull magical swords out of his own damn chest.
Half alive. Half dead.
Hopefully not just a fancy way to say possessing his own corpse.
He doesn’t have time to deal with every file - he’ll “confiscate” one of their USBs with a copy of everything for himself before leaving the rest to Batman & co, of course, minus the halfa files (a small part of him wants to shove his condition in Bruce’s face and demand he kill the clown again even though he knows it’s a futile hope, but the rest - the same part that snapped and denied and refused to say he was a meta less that a day ago now - cannot stomach the thought of even more rejection. Of a Bruce that believes he’s a monster. Of a Bruce that mourns him even while he’s right there. Or at least, more than he already does.) - but while the files copy he take the time to look at Danny’s.
The image has two people, Danny Fenton on one side and a version of the kid in a black hazmat suit with white hair, tanned skin, and painfully familiar green eyes. And floating.
~~~
Human Name: Danny Fenton
Ghost Name: Danny Phantom
Species: Halfa (half-human, half ghost)
~~~
It’s the section after that that makes Jason’s breath catch in his throat.
~~~
Death: The Portal Accident
So like, there was no audio (thank GOD I do not want to hear myself screaming) so. Details: When the portal didn’t work when they plugged it in mom and dad left for fudge, Jazz went to try and talk them into a more realistic career choice than ghosts. Sam and Tucker came over and Sam dared me to climb in and check it out - it was broken anyway so no harm. Except it wasn’t broken, just that my parents put the on button inside. Which I caught myself on when I tripped on a wire.
Anyway, electrocution! 
(T - Danny for the love of god be more serious, the cheerful tone is creepy)
(D - Hey! I’m the one who died! Shouldn’t I at least get to write my own epitaph)
(S - …Danny this is not an epitaph. You don’t even HAVE a grave)
(D - wow way to rub it in Sam)
(T - yeah Sam)
(S - ugh! Whatever, just stop with the chatting in official files)
(T - “official”)
(S - Tucker.)
(T - shutting up now)
Electrocution! I got zapped to death, but the ectoplasm from the portal was also opening up on top of me and a lot got bonded to me I guess (S - probably because of the electricity with how you ended up with some of Vortex' powers for a little while) at the same time said electricity was reviving me? - probably getting my heart beating again or something, I was a little busy screaming to pay attention (T - yeah okay we're going to Nasty Burger after this. And playing Doomed) - not that it would’ve mattered without the ghostification preventing me from melting me all the way to death.
Status: Me!
Powers:
Chirps! (ghost echolocation of some kind! humans can't hear em - halfas can, of course, in either form)
Form Change (really Sam? This barely counts)
Human form
Ghost form (no need to breathe)
Flight (last clock speed 210mph) (T - and climbing. Dang dude)
Invisibility (S - don’t forget shareable.) (Shareable. sigh)
Intangibility (Shareable)
Ecto Rays (eyes & hands) (T - and butt) (D - dude! I’m deleting that. Tucker why can't I delete it. TUCKER) (T - bow down in awe of my ksill) (S - ksill) (D - ksill) (T - yeah okay it’s permanent now) (D - aw man!)
Ghost Sense (S - why do we never test your range?) (D - no need? They always make themselves obvious or are being sneaky specifically to annoy me so *shrug*) (S - I still think we should test it)
Power Absorption (that time with Vortex’s weather powers)
Cryokinesis (Wayyyyy to much ice. NOT testing max output on that) (T - yeah frozen city was enough, let’s not cause an ice age. Tech needs some cool but too much is still bad and I just upgraded Patricia)
Ghostly Wail (cone of destruction, very exhausting - always at max output. Not to be used)
GHOST FORM ONLY (but really just never)
Cartoon Body (D - what???) (S - Freakshow literally turned you into a puddle and you just turned back and were fine. I don’t know what else to call that) (D - okay fair. but:)
GHOST FORM ONLY
Physical Enhancement (better strength, speed, stamina, durability, reflexes, balance, etc much better than human) (T - why does this look like dnd knockoff stats haha)
GHOST FORM ONLY (S - obviously mr last place in PE)
Resistances (pretty solid on the overshadowing, avoided being taken in by Ember until targeted, didn’t get turned to stone during the Medusa thing) (S - which was pure luck! Be careful!)
Ecto Electricity (ghost stinger, but I really don’t think this counts Sam. I mean I just. Make my ecto zappy. But it’s still just ecto) (S - so is your ICE and you don’t just call that "just cold ecto") (D - fine, but it feels overly specific) (S - maybe writing it all down will make you stop. Forgetting. POWERS!) (D - come on Sam that was a lucky hit! I was distracted! And it turned out fine!) (S - Fenton…) (D - oop okay doing fire now)
Ecto Fire (made Dash’s shoes melty that one time by make the ecto hot) (T - really needs more testing)
Tech possession (chasing Technus into computers, not very tested)
Ghost form only, i guess?
Overshadowing (control people, copy their voice, invade dreams - the control one erases the person’s memory so they don’t know they were overshadowed just lost time. I hate Walker. SO much) (T - rip Danny’s reputation, you’ll be missed)
Probably ghost form only
Duplication (T - That’s optimistic) (D - I’M WORKING ON IT OKAY!?) (S - pretty sure it just falls under cartoon body until you can actually separate) (D - :( betrayal)
Probably ghost form only
More? (D - ugh I hope not) (T - hey don’t say that, maybe you’ll get a power to make the JL give a crap about Amity) (D - honestly I’m getting pretty close to letting Boxy loose in Gotham) (S - Danny, don’t stoop to their level!) (D - it's only box ghost!) (T - I mean he has a point)
~~~
Jason changes his mind, seeing the commentary, and deletes the entire hidden file from the computer as soon as his copy is made. He can go over everything and bring any important info to Bruce separately, the bat’s can just chew on the parents’ files for now.
Once the original files are thoroughly and irretrievably removed he pockets his shiny new USB, makes a second one with all the official files, and heads back up and out - carelessly brushing past a thoroughly irate Red Robin with a pair of firemen and broken jaws of life. And not a scratch on the door; impressive - just in time to get Oracle’s text that he’s got 2 hours and 16 minutes to be at the location on his HUD so he can “arrive” to Amity.
And a fresh set of civilian clothes will be waiting in the plane, Alfred as reliable as ever.
“Files,” he says, tossing the safe USB to Batman and interrupting his interrogation of the police officer.
He catches it effortlessly of course, but the officer stops paying attention to him to jolt at Hood’s reappearance - even outside of Gotham his reputation is fierce.
“I sent a copy to myself. I’ll review them and give you an overview, but other than that consider this the end of my involvement in this little shitshow,” he says, continuing smoothly to the door. “I’m heading back to Gotham.”
Now, he has a little over two hours before Jason Todd needs to arrive in Amity Park. He only needs to lay hands on a laptop that he can isolate from Babs’ influence and he should be able to review the Halfa files in full before he "lands" - after he figures out just why the kid has a grudge against the JL.
#The defenses only attacked jason because the others are liminal#But not quite liminal enough for the Fenton House to pick up on#He’s the only one who died and had it really *stick* thus why he’s the only halfa#Sure the others died but they were all revived fully#Death left a stain#Not a chain#Jason has one foot in the grave#The others bat’s just have some graveyard dirt smudged on their pants cuffs#I can keep going with the metaphors#lol#Anyway#Their contamination is. Like. not worse than the average person living on the opposite side of the city as the Fentons#(which is a lot compared to everyone else in the whole world#but not much in terms of “will the house shoot me”#Fenton ghost detecting devices aren’t that precise yet)#The “files” aren’t super professional because like. They’re 14.#It’s organized sure but it’s not gonna be scientific paper levels (& they’d feel uncomfy making it too scientific sounding)#There’s powers missing on purpose (not thinking of thing as a power. All 3 forgot about it. Etc)#So why did the JL ignore Amity you ask?#Info blackout#One does not simply ignore the Meta Protection Acts and pretend to be a gov’t agency without taking precautions#Everything out of Amity Park is sanitized as hell. (ha#and doesn’t that just fit the GIW clean-obsession)#“But Mutable!” I hear you cry “What about Undergrowth & Vortex!”#I don’t remember Undergrowth’s radius of effect but I’m saying my AU he was Amity-only and the GIW set up a blockade to intimidate witnesse#Same deal with Pariah town-knapping the place (GIW base was JUST out of the town-knapping radius. Lucky them)#As for Vortex#the storms themselves made it impossible to track anything through normal means#(ie no cams caught Sam & Tucker’s jet taunting Vortex except some people with cells on the street. But wind killed all the audio)#So as far as the world is concerned there was a freak storm and it went away
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mrklonn · 3 months ago
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yep...
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alleyesony0u · 24 days ago
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evbo wakes up in pvp civilization remembering only three things — his name, his age, and his birthday. he knows it’s some… vague date. he tries to keep track of his days in his home. he is turning fifteen in a few months, after all. wouldn’t want to miss the big one five.
he tries to keep track of the days in his cell too. markings scraped on the walls that tell him time has passed. too much time. one day he wakes up with a horrible feeling of dread deep in his gut. like a black hole. when he goes to mark the day on the wall, it takes him a moment to register the fact that it’s his birthday. congrats kid. you’re fifteen now. do you like chocolate or vanilla? buttercream or fondant? a year from now you can get that car you wanted. for now, how about that exciting new video game or a pair of new kicks?
happy birthday, kid. they’re opening up the door now with shiny blades and prayers. or shiny blades and looks of cruel glee. do you really think they care? do you think when your blood stains the crevices of all the tiny markings on your wall they look at it and think, happy birthday kid, you’re fifteen?
happy birthday, kid. you’re still waking up with a gasp and a new scar, morphing into all the old ones on your skin. that pillow is comfortable, maybe you lay there for a while and dream. not the best present in the world but it’s better than nothing, no?
happy birthday, kid. the guard coming to collect you is the better one, even with all his sneers and insults. he leads you to the red gate and wishes you luck and when you turn to look at him and say “it’s my birthday today. i’m fifteen.” his mask will slip and he will look upon the wobbly kneed calf in horror as the stone door grinds shut behind you.
happy birthday, kid. you’ve died again and the guard coming to collect you is the worse one. he shoves you forward and his patience is tick tick ticking. you could tell him it’s your birthday today, but that wouldn’t change much. birthdays don’t divert destinies.
happy birthday, kid. you’re sitting in your own gore but you’ve managed to snatch a flint and steel at one of your respawns and a twig from one of the trees you pass by on your way down. you light the twig with the flame and it is warm. and it is light. and your cell is so very cold and dark. you close your eyes and make a wish. or two. or three. i want to save tabi. i want to go home. i don’t want to die.
you blow out your makeshift candle and the cell is cold and dark again. not for long though, because the door opens again and your blood spatters on the walls and floors. again. happy birthday, kid. you’re fifteen. remember what you were born for.
and as the day dwindles to its close, a man adorning a golden crown, dressed in yellow opens the door. he says, “fifteen, huh?”
and you ask, “you know my birthday?”
and he says, “of course i do. it’s just practical.”
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eightspringdays · 4 months ago
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Death Note 29: Father
"Your true name is Mihael Keehl."
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lotus-pear · 1 year ago
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regret
#literally excuse the shitty anatomy and cell shading i was thinking abt chuuyas reaction to what he'd done and i decided to make it skk#bc skk copium :')#the way i've hated dazai so fucking much but i still cried like a bitch when he died#he's not dead the bsd fandom has this phase like the elevator chapter where we're like ''dazai's not gonna make it he's done for!!''#and then he comes back next chapter like surprise bitches yall thought i was dead lmao#this chapter fucking HURT for skk shippers tho like we rly lost this time around huh#deluding myself into thinking that chuuya used gravity manipulation to slow the bullet#bc we didn't see a bullet hole behind dazais head like when chuuya shot his shoulder even though the bullet to his skull was fired at close#the reason theres a wound is bc the compressed air that was still fired was enough to wound him#and the shock wave that followed caused him to pass out bc of the sudden tension to his head intermingled with the blood loss and poison#we also know dazai can control his heart rate at will so maybe he can drop his pulse to zero for like thirty secs#enough to make fyodor believe he's dead#in the event that all of this is untrue and dazai rly does die the way my entire being will go numb and cold and dead#knowing that fyodor will most likely use dazai's death as a weapon against chuuya effectively chaining him to his side#like bffr chuuya may dislike dazai but that's his partner his reflection the boy that makes him desperately want to be human#dazai is the embodiment of chuuyas humanity and once chuuya loses that tether to his human side he will snap and the facade will shatter#and we will truly see chuuya unhinged with nothing more keeping him bound to his mortal shell#this wasn't the skk reunion we wanted asigiri what the fuck :(#bungou stray dogs#bungo stray dogs#bsd#nakahara chuuya#chuuya nakahara#osamu dazai#dazai osamu#skk#soukoku#lotus draws
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hmtaxidermy · 1 year ago
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Shoutout to this massive buck that had a third antler growing in
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poisonousquinzel · 1 month ago
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they deserved better idc 😐
#it was so cool seeing the sign language and isha being mute was never something that needed fixing#she found a home and jinx found a reason to live#i know people are saying jinx survived because of the scene with Caitlyn but like...#why would jinx do that? she wanted to die this whole season she wanted to die at the beginning of the episode & that depression never faded#her escaping through the air vents implies a will to live#something jinx did not have#i thought it felt like the ending of ep 7 in the season one#trying to kill herself with ekko cause she didnt want to die alone. she had warwick when she pulled out & detonated one of her monkey bombs#like I'd love it if she was alive and left cause yea fuck Piltover get outta there honey!#and Isha's sacrifice meant nothing. she's just not mentioned at all we didnt even see Sevika's reaction to her death...#not dc#arcane#arcane spoilers#jinx arcane#isha arcane#tw suicide mention#the ending with Caitlyn felt like another moment of her and Vi having no idea the severity of Jinx's mental health issues#vi was upset she didnt wanna fight and go make change and shit and never mentioned the ''my sister wants to kill herself''#as if jinx wasn't in a depressive state every time we saw her in that cell.#and her removing herself from the equation so the others can be happy is ??????#so i guess she was a jinx to her family??? that she was the problem? its a frankly gross message to send with a suicidal character#that yes actually your loved ones will be better off without you in the picture you complicate things
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valfeathers · 2 years ago
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gtfo hes playing minecraft
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silverskye13 · 3 months ago
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The Red Star
Doodle of my DnD group that got a little out of hand whoops.
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reasonsforhope · 8 months ago
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"In a first-ever human clinical trial, an mRNA cancer vaccine developed at the University of Florida successfully reprogrammed patients’ immune systems to fiercely attack glioblastoma, the most aggressive and lethal brain tumor.
The results in four adult patients mirrored those in 10 pet dog patients suffering from brain tumors whose owners approved of their participation.
The discovery represents a potential new way to recruit the immune system to fight treatment-resistant cancers using an iteration of mRNA technology and lipid nanoparticles, similar to COVID-19 vaccines, but with two key differences: use of a patient’s own tumor cells to create a personalized vaccine, and a newly engineered complex delivery mechanism within the vaccine.
“Instead of us injecting single particles, we’re injecting clusters of particles that are wrapping around each other like onions,” said senior author Elias Sayour, M.D., Ph.D., a UF Health pediatric oncologist who pioneered the new vaccine, which like other immunotherapies attempts to “educate” the immune system that a tumor is foreign.
“These clusters alert the immune system in a much more profound way than single particles would.”
Among the most impressive findings was how quickly the new method spurred a vigorous immune-system response to reject the tumor, said Sayour, principal investigator at the University’s RNA Engineering Laboratory and McKnight Brain Institute investigator who led the multi-institution research team.
“In less than 48 hours, we could see these tumors shifting from what we refer to as ‘cold’—very few immune cells, very silenced immune response—to ‘hot,’ very active immune response,” he said.
“That was very surprising given how quick this happened, and what that told us is we were able to activate the early part of the immune system very rapidly against these cancers, and that’s critical to unlock the later effects of the immune response,” he explained in a video (below).
Glioblastoma is among the most devastating diagnoses, with median survival around 15 months. Current standard of care involves surgery, radiation and some combination of chemotherapy.
The new report, published May 1 in the journal Cell, is the culmination of seven years of promising studies, starting in preclinical mouse models.
In the cohort of four patients, genetic material called RNA was extracted from each patient’s own surgically removed tumor, and then messenger RNA (mRNA)—the blueprint of what is inside every cell, including tumor cells—was amplified and wrapped in the newly designed high-tech packaging of biocompatible lipid nanoparticles, to make tumor cells “look” like a dangerous virus when reinjected into the bloodstream to prompt an immune-system response.
The vaccine was personalized to each patient with a goal of getting the most out of their unique immune system...
While too early in the trial to assess the clinical effects of the vaccine, the patients either lived disease-free longer than expected or survived longer than expected. The 10 pet dogs lived a median of 4.5 months, compared with a median survival of 30-60 days typical for dogs with the condition.
The next step, with support from the Food and Drug Administration and the CureSearch for Children’s Cancer foundation, will be an expanded Phase I clinical trial to include up to 24 adult and pediatric patients to validate the findings. Once an optimal and safe dose is confirmed, an estimated 25 children would participate in Phase 2."
-via Good News Network, May 11, 2024
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-video via University of Florida Health, May 1, 2024
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dailycupofcreativitea · 2 years ago
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Of course it was Gohan 🙄
(Based off a reply to this tweet!)
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