#circovirus

[cilginfizikcilervbi]

Yeni Bir Karaciğer Virüsü Bulundu

Yeni Bir Karaciğer Virüsü Bilim insanları, geçici olarak insan sirkovirüsü 1 (HCirV-1) olarak adlandırılan, önceden bilinmeyen bir sirkovirüs türü tanımladılar. Sirkovirüsler; solunum, böbrek, dermatolojik ve üreme sorunlarına neden olabilecekleri çeşitli hayvan türlerinde ilk olarak 1974’te tanımlanan küçük, oldukça dirençli DNA virüslerinin bir ailesidir. HCirV-1, bilinen hayvan…

[megachirottera]

Da quanto tempo consumi carne di maiale con terapia genica?

Se hai gustato uno dei prodotti a base di carne preferiti in America, hai mangiato carne gene… Source: April 10, 2023; Analysis by Dr. Joseph Mercola [>Fact Checked<] (more…) “”

[reality-detective]

“I gathered all vaccine ingredients into a list and contacted Poison Control. After intros and such, and asking to speak with someone tenured and knowledgeable, this is the gist of that conversation.

Me: My question to you is how are these ingredients categorized? As benign or poison? (I ran a few ingredients, formaldehyde, Tween 80, mercury, aluminum, phenoxyethanol, potassium phosphate, sodium phosphate, sorbitol, etc.)

He: Well, that's quite a list... But I'd have to easily say that they're all toxic to humans... Used in fertilizers... Pesticides... To stop the heart... To preserve a dead body... They're registered with us in different categories, but pretty much poisons. Why?

Me: If I were deliberately to feed or inject my child with these ingredients often, as a schedule, obviously I'd put my daughter in harm's way... But what would legally happen to me?

He: Odd question... But you'd likely be charged with criminal negligence... perhaps with intent to kill... and of course child abuse... Your child would be taken away from you... Do you know of someone's who's doing this to their child? This is criminal...

Me: An industry... These are the ingredients used in vaccines... With binding agents to make sure the body won't flush these out... To keep the antibody levels up indefinitely...

The man was beside himself. He asked if I would email him all this information. He wanted to share it with his adult kids who are parents. He was horrified and felt awful he didn't know... his kids are vaccinated and they have health issues...”

~  By  Iris Figueroa

Here are just SOME vaccine ingredients present in routine vaccines:

◾️Formaldehyde/Formalin - Highly toxic systematic poison and carcinogen.

◾️Betapropiolactone - Toxic chemical and carcinogen. May cause death/permanant injury after very short exposure to small quantities. Corrosive chemical.

◾️Hexadecyltrimethylammonium bromide - May cause damage to the liver, cardiovascular system, and central nervous system. May cause reproductive effects and birth defects.

◾️Aluminum hydroxide, aluminum phosphate, and aluminum salts - Neurotoxin. Carries risk for long term brain inflammation/swelling, neurological disorders, autoimmune disease, Alzheimer's, dementia, and autism. It penetrates the brain where it persists indefinitely.

◾️Thimerosal (mercury) - Neurotoxin. Induces cellular damage, reduces oxidation-reduction activity, cellular degeneration, and cell death. Linked to neurological disorders, Alzheimer's, dementia, and autism.

◾️Polysorbate 80 & 20 - Trespasses the Blood-Brain Barrier and carries with it aluminum, thimerosal, and viruses; allowing it to enter the brain.

◾️Glutaraldehyde - Toxic chemical used as a disinfectant for heat sensitive medical equipment.

◾️Fetal Bovine Serum - Harvested from bovine (cow) fetuses taken from pregnant cows before slaughter.

◾️Human Diploid Fibroblast Cells - aborted fetal cells. Foreign DNA has the ability to interact with our own.

◾️African Green Monkey Kidney Cells - Can carry the SV-40 cancer-causing virus that has already tainted about 30 million Americans.

◾️Acetone - Can cause kidney, liver, and nerve damage.

◾️E.Coli - Yes, you read that right.

◾️DNA from porcine (pig) Circovirus type-1

◾️Human embryonic lung cell cultures (from aborted fetuses)

You can view all of these ingredients on the CDCs website: 👇

You are always welcome to do your own research, in fact I encourage you to do so. 🤔

[theramseyloft]

What’s your opinion on pigeon racing and flying? Do you think it benefits the health or tractability of a breed or could it ever be done in modest ways without the large aspects of neglect?

Ooh, this is a tough one.

Racing, in particular, is not exclusively for entertainment.

Just like riding horses or running sled dogs isn't.

The races that earn the biggest pot, for example? Supply breeding stock to the parts of the world that still exist where they are depended upon as messengers, and having them or not is still a matter of life and death.

Hell, if anything ever happened to our current means of electronic communication, Racing Homers are very literally the best possible alternative to fall back on, historically tried and tested.

And because their ability to navigate is central to meeting that need, training tosses and actual races are genuine necessities that cannot be replaced by any other means.

So I can't, in good conscience, say that the breed or practice should die out.

That said, GPS trackers are much smaller, cheaper to make, and easier to come by, though I don't know what kind of power they would need to transmit in real time, or if the addition of that would make it too heavy to carry.

If a GPS capable of real time transmission could be made small and light enough for a racing homer to carry without effecting their flight speed, I would love to see them used in tosses and races so that races could be monitored and birds who stop flying either very suddenly during the day or longer than it takes to wait out a night can be recovered.

A volunteer team of spectators would be ideal for that.

I can see some potential down sides to this, like people tracking the birds specifically to take pot shots at them, or trying to find a way to intercept and steal some, but a healthy racing homer's base speed is 60mph, with some sprinting lines clocked at up to 100.

And unless they physically can't, they do not stop until they get back!

The average person isn't going to be able to trap or catch that bird unless something is seriously wrong.

And having the on-the-move flight data in real time would be valuable to racers both for the data itself and as a means to draw spectators.

There isn't an aviary on the planet big enough for the length of sustained flight from which the musculature of the Performing breeds has developed, but we have ways to artificially enhance the immune system: Vaccines.

Natural immune systems develop over generations of survival.

Pathogens adapt to their host by becoming less lethal over time.

No host? No spread. Pathogen population dies out, and that strain becomes a dead end.

Hosts adapt to their pathogens over time by developing more and more aggressive immune responses with each exposure.

Vaccines work by presenting the immune system with the means to identify a pathogen without the damage to the host that would usually happen while the body is trying to organize the response to take it out.

We have vaccines for Paramyxovirus and Paratyphoid. There is an inoculation for Pox.

It would be amazing to have a full vaccine for Pox, not to mention Adenovirus, Circovirus, avian flu, and ornithosis, or if it were possible to vaccinate against protozoa like coccidia and trich.

Honestly, the improvement of medicine is a matter of time and funds.

In the mean time, all we can do is our best to selectively breed hosts with strong immune responses to the pathogens we don't have vaccines for yet.

[aressida]

Wrote a long one cos the in law family wanted him to take the flu shot, I said no.

"Dear Family, Friends, and Medical Professionals,

I am writing to share some thoughts and questions about vaccines, particularly in light of recent developments.

Do we believe that vaccines are the ultimate solution in medicine?

It is commonly known that influenza vaccines are reformulated each season due to the virus’s constant mutation, making it challenging to predict and protect against new strains accurately.

Is it true that these vaccines bypass the liver’s natural filtration system, potentially causing a shock to our bodies?

How should we classify these ingredients—as toxic or benign?

Here are just some vaccine ingredients, and these are being injected into your body and into your children’s bodies if you choose to vaccinate:

– Formaldehyde/Formalin – Highly toxic systemic poison and carcinogen.

– Betapropiolactone – Toxic chemical and carcinogen. May cause death or permanent injury after very short exposure to small quantities. Corrosive chemical.

– Hexadecyltrimethylammonium bromide – May cause damage to the liver, cardiovascular system, and central nervous system. May cause reproductive effects and birth defects.

– Aluminum hydroxide, aluminum phosphate, and aluminum salts – Neurotoxin. Carries risk for long-term brain inflammation/swelling, neurological disorders, autoimmune disease, Alzheimer’s, dementia, and autism. It penetrates the brain where it persists indefinitely.

– Thimerosal (mercury) – Neurotoxin. Induces cellular damage, reduces oxidation-reduction activity, cellular degeneration, and cell death. Linked to neurological disorders, Alzheimer’s, dementia, and autism.

– Polysorbate 80 & 20 – Trespasses the blood-brain barrier and carries with it aluminum, thimerosal, and viruses; allowing them to enter the brain.

– Glutaraldehyde – Toxic chemical used as a disinfectant for heat-sensitive medical equipment.

– Fetal Bovine Serum – Harvested from bovine (cow) fetuses taken from pregnant cows before slaughter.

– Human Diploid Fibroblast Cells – Aborted fetal cells. Foreign DNA has the ability to interact with our own.

– African Green Monkey Kidney Cells – Can carry the SV-40 cancer-causing virus that has already tainted about 30 million Americans.

– Acetone – Can cause kidney, liver, and nerve damage.

– E. Coli – Yes, you read that right.

– DNA from porcine (pig) Circovirus type-1

– Human embryonic lung cell cultures (from aborted fetuses)

You can view all of these ingredients on the CDC’s website. I encourage everyone to do their own research. Look up the MSDS on these chemicals. Read the thousands of peer-reviewed studies that have evaluated the biological consequences these chemicals can have on the body, especially when being injected.

Injecting foreign substances directly into the bloodstream—viruses, toxins, and proteins—has been linked to various diseases and disorders. These include conditions like atypical measles, cancer, leukemia, multiple sclerosis, and even SIDS (Sudden Infant Death Syndrome).

Conditions like Addison’s disease, anaphylactic shock, arthritis, asthma, asymptomatic COVID-19, Crohn’s disease, epilepsy, facial paralysis, fibromyalgia, fetal distress syndrome, foreign body embolism, genital herpes, hepatitis, hyperthyroidism, inflammatory bowel disease, jugular vein embolism, lung abscess, lupus, meningitis, MERS-CoV test positive, migraine-triggered seizures, multiple organ dysfunction syndrome, multiple sclerosis, multisystem inflammatory syndrome in children, pneumonia, stiff leg syndrome, stiff person syndrome, stillbirth, sudden heart attack, sudden respiratory failure, type 1 diabetes, uterine rupture, viral bronchitis—and much more.

This does not mean everyone will experience these reactions, but a significant number of test subjects have experienced one or more.

It is more than enough evidence to show that vaccine mandates are completely anti-scientific.

How can you make an informed decision if you do not have all the information?

We have also seen a shift where flu vaccines are now mRNA-based. But does a "vaccine" really prevent a virus or its recurrence as we expect it to?

The annual flu shot is, at best, a partial defense, aimed at last year’s strain. Does it truly help against the ever-mutating new flu, or is it just a temporary fix?

My concern is that this mindset—that a vaccine is a quick fix for everything—is flawed. The immune system may struggle to handle these types of agents, leading to breakthrough infections and potentially higher mortality rates.

For those who are vaccinated, I respect your choice. I simply ask for the same respect in return for my decision not to vaccinate. My reasons are personal and grounded in a belief that the government should not dictate my health choices and my family's.

Have you heard about Pfizer’s side effects?

Have you read the Pfizer documentation? Ask yourself if a drug with 32 pages of side effects is right for you.

The list of potential vaccine side effects released by Pfizer is alarming, ranging from autoimmune disorders to serious conditions like multiple organ dysfunction and sudden respiratory failure. Yet, this information was kept under wraps and only recently made public. Shouldn’t we be informed of the risks?

Do we even know the medium- or long-term effects of these vaccines?

Are they still in clinical trials? Is there a control group? What about Antibody-Dependent Enhancement (ADE) – has it been adequately tested? And why are ingredients like formaldehyde and mercury, known toxins, included in these vaccines?

Do you truly think this vaccine is 100% safe?

Transparency is crucial.

How can we make informed decisions if we are not given all the information?

We must ask ourselves, do we trust the pharmaceutical companies and their relationships with organizations like the CDC and FDA?

The FDA requested 75 years to release data on the Pfizer vaccine—why? Why did it take only 108 days to approve this vaccine, yet it supposedly requires decades to fully understand its effects?

Do you believe that SARS-CoV-2 has been isolated?

How well-informed are you about the CDC, FDA, pharmaceutical companies, and their donors? Do you think their qualifications are reliable?

These are important questions that deserve honest discussions. And, I believe it is crucial to acknowledge the existence of these alternative perspectives and engage in open discussions to gain a more comprehensive understanding.

Our health and freedom are at stake, and I urge everyone to think critically and seek out all the information before making decisions.

Thank you for taking the time to consider these points."

[despazito]

Psittacine circovirus coming soon to a herp near you!

[cyanocoraxx]

these sure are some words. wtf is circovirus like infection I'm gonna kill u

[science-sculpt]

Tiny Terrors with a Twist: Demystifying the Microscopic Marvels We Call Viruses

They're tinier than bacteria, simpler than cells, and yet they've got the whole world on edge- Viruses. The mere mention conjures images of sniffles, fevers, and global pandemics. But these microscopic marvels are far more complex and intriguing than just villainous germs. The world of viruses, where the line between life and non-life gets blurry, and surprises lurk around every protein spike. These enigmatic entities is far more surprising, and even a little strange.

First things first: are they even alive? It's a tricky question. They lack the key features of traditional life – no cells, no metabolism, no independent growth. But they carry genetic material, can evolve, and replicate inside host cells, blurring the lines. Think of them as genetic hitchhikers, commandeering the machinery of living cells to fulfill their own reproductive desires.

Let's ditch the villainous stereotype. While some viruses do cause disease, many play crucial roles in the environment and even within our own bodies. For instance, bacteriophages, also known as phage, are viruses that specifically target and kill bacteria. These tiny warriors help keep bacterial populations in check, playing a vital role in maintaining healthy ecosystems. Additionally, some viruses have been shown to boost our immune system and even offer protection against certain cancers. Talk about plot twists!

It's easy to underestimate something a million times smaller than a grain of sand. But don't let their size fool you. The world's smallest known virus is so small it could fit inside a single human protein! Its name? The Porcine circovirus type 1. Tiny but mighty! Viruses are master manipulators, capable of hijacking the machinery of living cells to replicate and spread. In fact, recent research suggests that viruses might be even more adaptable than we previously thought. A 2023 study published in Nature revealed a unique virus found in deep-sea hydrothermal vents that has rewritten its own genetic code, potentially hinting at hidden complexities in viral evolution.  The world of viruses is constantly throwing curveballs. Recently, scientists discovered a giant virus in Siberian permafrost that had been frozen for 30,000 years! It raises questions about how long viruses can survive and the potential risks of thawing permafrost in a warming world.

From bats-to-labs, Remember those scenes in movies where a zoonotic virus jumps from animals to humans? Turns out, that's not just Hollywood fiction. Scientists believe the COVID-19 pandemic originated from bats, highlighting the importance of understanding human-animal relationships and preventing future outbreaks. But don't blame all the blame on bats! Research suggests that human encroachment on natural habitats and the wildlife trade are bigger contributors to zoonotic spillover events.

While some viruses pose significant threats, we're not defenseless. Vaccines, those tiny doses of immunity, are a testament to human ingenuity. The recent success of mRNA vaccines against COVID-19 has revolutionized vaccine development, offering hope for faster and more effective responses to future viral threats.

Knowledge is power, even when it comes to viruses. By understanding these tiny invaders, we can better prepare for future outbreaks, develop innovative treatments, and appreciate the complex dance between life and its microscopic hitchhikers. So, the next time you hear about a virus, don't panic. Instead, remember the incredible science happening behind the scenes, and the fascinating world of these enigmatic players in the grand game of life.

[blizz4rd1203]

Porcine circovirus 2 is an angel to me

[o-craven-canto]

I think I've already posted it somewhere, but just in case, here is the genome of the porcine circovirus, the smallest in the world:

That's it. The whole thing. 1768 base pairs, a total of three genes (two for capsid proteins, one to replicate DNA). For comparison, the smallest bacterial genome, belonging to an intracellular parasite, has about 110,000 base pairs and 137 genes. The human genome counts about three billion base pairs and, depending on the count, some 20,000 genes.

[schlauemaus]

Porzines Circovirus 2

Erreger: Porzines Circovirus 2 (=PCV2), kleines unbehülltes ssDNA-Virus ubiquitäres Vorkommen genetisch hohe Variabilität, relativ stabil gegen Desinfektionsmittel u. hohe Temperaturen 6 verschiedene Subtypen, heute herrscht PCV2d vor

Übertragung:

Ausscheidung über alle Körper Se- u. Exkrete

oronasal

über Samen

transplanzentar

Pathogenese:

Initiale Virusreplikation in Tonsillen Primärer Befall v. lymphatischem Gewebe, aber auch viele andere Gewebe (zB Lunge, Darm, Herz, Niere, Leber, Gehirn)

Zielzellen: mononukleäre Blutzellen (Makrophagen u. dendritische Zellen) -> dort Vermehrung -> generalisierte Lymphozytendepletion -> Immunsuppression

Symptome: Unterscheidung sieben verschiedener Erscheinungsformen

Systemic disease (=Post weaning multisystemic wasting syndrome) bedeutendste Verlaufsform betrifft Absatzferkel (5.-7. Lebenswoche) Mortalität bis 20%

"Kümmern nach dem Absetzen"

struppiges Borstenkleid + übergroßer Kopf im Körperverhältnis

Gewichtsverlust

Blässe

Typisch: vergrößerte Inguinallymphknoten (aber nicht zwingend)

Atemwegsprobleme

Durchfall

evtl. Ikterus

Lung disease Teil v. PRDC, nur Lunge betroffen! 15.-22. Lebenswoche

Dyspneo

Enteric disease gelegentlich bei Absatz- u. Mastschweinen

Durchfall

Reproductive disease betrifft Jungsauen intrauterine Verteilung zw. Feten extrem langsam Tropismus zu fetalen Myocardzellen -> Feten sterben an Herzversagen

Umrauschen

SMEDI

Aborte

Neurologic disease

Opisthotonus

Nystagmus

Krämpfe

Procines Dermatitis u. Nephropathie Syndrome (=PDNS) betrifft Mastschweine hohe Mortalität

Hautveränderungen (Perianalgegend, Hintergliedmaßen, Flanken) erst kleine, rote, leicht erhabene Papeln -> dann rundlich dunkelrot -> flächenhaft konfluierende Blutungsareale wg. Gefäßschäden

Subclinical infection

Auseinanderwachsen

reduzierte Tageszunahmen

keine weiteren Symptome, aber evtl. Koinfektionen

Diagnose

Für Diagnose v. PMWS (=systemic disease) muss TRIAS erfüllt werden -> Klinik -> Typische pathologischer Veränderungen (siehe unter Sektion) -> Direkter Erregernachweis mittels Färbemethoden od. qPCR

Sektion u. Histologie:

PMWS vergrößerte Inguinallymphknoten (muss aber nicht sein) Lymphgewebe: mgr.-hgr. Lymphozytendepletion mit granulomatöser Entzündung, evtl. traubenförmige intrazytoplasmatische Einschlusskörperchen interstitielle Pneumonie, ggr.-hgr. nekrotisierende Bronchiolitis lung disease granulomatöse bronchio-interstitielle Pneumonie mit/ohne Bronchiolitis bronchioläre Fibrose Enteric disease granulomatöse Enteritis, verdickte Darmschleimhaut Payer`sche Platten: Lymphozytendepletion vergößerte Mesenteriallymphknoten Reproductive disease Feten mit myocardialer Degeneration (Nekrosen/Fibrosen) nicht-eitrige/ nekrotisierende Myocarditis Neurologic disease nicht eitrige/ granulomatöse Encephalitis PDNS bds. vergrößerte Nieren fibrinös-nekrotisierende Glomerulitis + nicht eitrige interstitielle Nephritis systemisch nekrotisierende Vaskulitis subclinical infection keine/ nur ggr. Lymphozytendepletion

Direkter Erregernachweis

Probenmaterial: primär betroffenes Gewebe PMWS: lymphatisches Gewebe (zB Inguinallymphknoten) lung disease: Lunge enteric disease: Peyer`sche Platten reproductive disease: Herzen v. Totgeburten/Aborten mittels qPCR aus Gewebe od Serum mittels in-situ-Hybridisierung + Immunhistochemie (=Goldstandard) Sensitivität u. Spezifität hoch mittels Elektronenmikroskopie mittels Virusisolation

Antikörpernachweis

mittels ELISA zum Herdenscreening od. zur Erstellung v. Serumkonversionskurven !Keine Unterscheidung möglich v. Impf-, maternalen und Antikörpern v. einer Infektion! mittels Immunfloureszenztest mittels indirektem Immunoperoxidase-Monolayer-Test mittels Serumneutralisationstest

Prophylaxe

Rein-Raus-Verfahren, kein Zurückstallen

6-wöchtige Quarantäne f. Jungsauen/Eber

Kümmerer in Krankenbuchten

korrekte Reinigung u. Desinfektion

Impfprogramm an Betrieb anpassen Ferkelschutz -> Mutterschutzimpfung 3-4 Wo. vor Abferkelung Schutz vor reproduktiver Form -> Impfung vor Belegung Schutz vor PMWS -> Impfung in Säugezeit (=vor Absetzen)

Kanülen beim Impfen nach jeder Bucht wechseln

optimale Futterqualität, hochwertiges Eiweiß, Vitaminversorgung

Sauen vor Abferkeln Waschen + entwurmen

so wenig Ferkel wie möglich versetzen

alle Ferkel am selben Tag absetzen

keine Überbelegung (in Aufzucht: max. 2 Würfe pro Bucht)

Stallklima optimieren

Therapie

Symptomatisch

Managementmaßnahmen

evtl. Antibiose wg. Sekundärerregern

[notedoller]

https://www.verifiedmarketreports.com/pt/product/porcine-circovirus-type-2-pcv2-vaccine-market/

[neosciencehub]

Engineering Recombinant Chimeric Porcine Circovirus for Combating Porcine Viral Diseases: Dr. Madhuri

“Integrated disease control strategies are essential for combating the multiple viral infections affecting the pig population in India, which pose severe economic risks to farmers,” said Dr. Madhuri Subbaiah, Scientist-E at DBT-National Institute of Animal Biotechnology, Hyderabad. Presenting her paper, co-authored with Ms. Ruchi Malwade, at the Symposium on Strategies to Combat Economically…