#aml screening

[signzyblog]

https://www.signzy.com/us/

Signzy provides identity verification solutions to businesses to accelerate their user onboarding process. Our verification suite enables businesses to complete KYC, KYB and AML screening, and stay compliant with the regulatory requirements in 200+ countries globally.

[zigram-tech]

Unlocking Confidence in Compliance: AML Risk Assessment Solutions by Zigram

In the ever-evolving landscape of financial regulations, Zigram stands as your trusted partner in navigating the complexities of Anti-Money Laundering (AML) compliance. Our cutting-edge AML risk assessment solutions empower businesses to fortify their defenses against financial crimes and regulatory penalties.

Why Choose Zigram for AML Risk Assessment?

At Zigram, we understand the critical importance of robust AML risk assessment in safeguarding your financial institution. Our tailored solutions leverage advanced technology and industry best practices to provide a comprehensive evaluation of your compliance framework. By choosing Zigram, you embrace a proactive approach to compliance that not only meets but exceeds regulatory expectations.

Key Features of Zigram's AML Risk Assessment Services

Dynamic Risk Profiling: Our adaptive risk profiling ensures a nuanced understanding of evolving risks, allowing your business to stay one step ahead.

Automated Monitoring: Zigram's state-of-the-art technology automates the monitoring process, providing real-time alerts and reducing the risk of oversight.

Customized Solutions: Recognizing the uniqueness of each business, our AML risk assessment services are tailor-made to fit your specific requirements, ensuring a personalized and effective compliance strategy.

Seamless Integration for Lasting Compliance Assurance

Zigram seamlessly integrates AML risk assessment into your existing compliance framework, minimizing disruption while maximizing effectiveness. Our user-friendly solutions ensure that compliance doesn't hinder business operations but enhances them, fostering a culture of integrity and trust.

In a world where regulatory landscapes are ever-shifting, Zigram stands as your beacon of stability. Elevate your compliance game with Zigram's AML risk assessment solutions — fortify your defenses, mitigate risks, and stride confidently towards a compliant future.

[namescan]

Sanctions and pep screening | NameScan

[eastnetsblogs]

Top Reasons Why AML Screening Solution is Crucial for Financial Institutions

In this digitally connected financial landscape, there is a great need for regulatory compliance. As financial crimes, like money laundering, rise to the top, there is pressure on the banks and other financial institutions to secure their operations and customers. In such challenges, AML screening solutions have become an essential tool in preventing and detecting these illegal activities and keeping your business safe.  Let’s uncover the significant reasons for adopting screening solutions to deter money laundering. 

1. Reducing Risks from Financial Crimes:

AML screening tools help identify suspicious transactions and individuals associated with money laundering and terrorist financing, among other financial crimes. Through such solutions, financial institutions can reduce their risk of unknowingly indulging in illegal activities.

2. Ensuring Regulatory Compliance:

Financial institutions such as banks and fin-corps are bound to comply with strict regulations that are formulated to prevent financial crimes. Sophisticated watchlist screening solutions to prevent money laundering allow the banks to maintain compliance by monitoring continuous transactions while ensuring they live up to global and local laws; hence, averting the risk of reputational damages and penalties.

3. Improving Operational Efficiency:

With automated screening, financial establishments can speed up their processes, reduce the amount of manual workload, and improve the accuracy of investigations. It helps institutions to identify and address potential risks faster, thus saving time and resources.

In a Nutshell-

AML screening solutions have elevated financial institutions to a new level. They combine screening capability with cutting-edge features like detection management, list management, and detailed reporting. Ensuring compliance and preventing financial crimes has led to greater operational efficiency through such tools, which also form a critical part of the modern financial landscape.

[ldttechnology]

Safeguarding Your Business: Why Anti-money Laundering Software is Pivotal?

In today's increasingly digital world, financial transactions are happening faster and more frequently than ever before. While this presents immense opportunities for businesses, it also creates a prime environment for criminals to engage in money laundering activities.

This is where anti-money laundering (AML) software steps in, acting as a powerful tool for financial institutions and businesses to combat financial crime and protect themselves from significant reputational and financial risks.

What is AML Software?

AML software is a specialised software solution designed to help businesses comply with AML regulations and identify suspicious financial activity. It acts as a vigilant guardian, analysing vast amounts of transaction data and customer information to detect patterns and red flags that may indicate money laundering attempts.

The Significance of Anti-money Laundering Software

However, the importance of AML goes beyond preventing fraud. Here are some key reasons why AML software is crucial:

Mitigates financial risks: Money laundering activities can lead to significant financial losses for businesses. AML software helps detect and prevent these activities, safeguarding your bottom line.

Enhances customer trust: Implementing robust AML measures demonstrates your commitment to a secure financial environment, fostering trust and loyalty among your customers.

Maintains regulatory compliance: AML regulations are constantly evolving. AML software helps ensure your business stays compliant with the latest rules and regulations, minimising legal risks.

Boosts operational efficiency: Automating AML processes through software frees up valuable resources for core business activities, leading to greater operational efficiency.

What Features Does AML Software Offer?

Modern AML software is equipped with a comprehensive suite of features to combat financial crime effectively. Here are some key capabilities:

AML Transaction Monitoring Tools: These tools monitor transaction activity for suspicious patterns, such as large, unusual cash deposits or frequent transactions between high-risk countries.

Customer Due Diligence (CDD): AML software streamlines the CDD process, facilitating the collection and verification of customer information to assess their risk profile.

Reporting and Alerting: The software generates reports on suspicious activity and automatically alerts investigators of potential money laundering attempts.

Why Choose AML Software for Your Business?

In a world where financial transactions are happening at lightning speed, manual AML compliance methods are no longer sufficient. AML software offers a robust, automated solution that provides several benefits:

Improved accuracy: Software automates AML processes, reducing the risk of human error and ensuring consistent monitoring across all transactions.

Enhanced efficiency: Automating AML tasks frees up staff to focus on other critical business functions.

Cost-effectiveness: Investing in AML software can save your business money in the long run compared to the financial and reputational costs associated with money laundering violations.

Scalability: AML software solutions can easily scale to accommodate your business's growth, ensuring ongoing compliance with AML regulations.

Wrapping Up

As the digital landscape continues to evolve, the need for robust AML measures becomes even more critical. LDT Technology, with its cutting-edge financial fraud software equipped with aml transaction monitoring tools, can be your trusted partner in mitigating financial crime risks and safeguarding your business. Contact us today to learn more about our financial fraud software, and let’s build a secure and compliant financial environment.

[fari2023]

Sanction Screening Software in Financial Institution

Sanction screening software is a crucial tool used by financial institutions, including banks, to identify and screen individuals and entities against various government and international watchlists, sanctions lists, and politically exposed persons (PEP) lists. The primary purpose of this software is to ensure compliance with global regulatory requirements and prevent financial institutions from inadvertently engaging in transactions with sanctioned individuals or entities.

Features and functions of sanction screening software typically include:

Watchlist Screening: The software cross-checks customer data, such as names, addresses, and other identifying information, against various watchlists provided by regulatory bodies.

Real-Time Monitoring: Sanction monitoring software often operates in real time, enabling immediate identification of any matches or potential matches with sanctioned individuals or entities during account opening, transactions, or any other customer interactions.

Automated Alerts and Workflow Integration:the software generates alerts for further investigation and appropriate action and  can promptly review and handle potential matches in accordance with the institution's internal policies.

Configurable Risk Assessment: The software allows for customizable risk assessment parameters, enabling institutions to prioritize and manage different levels of risk associated with potential matches more effectively.

Compliance Reporting: It facilitates the generation of comprehensive reports and audit trails for regulatory compliance purposes, demonstrating the institution's efforts to screen and monitor customer activities in accordance with international sanctions and anti-money laundering (AML) regulations.

Data Security and Privacy: Sanction screening software typically ensures robust data security and privacy measures to safeguard sensitive customer information and maintain confidentiality while conducting screening activities.

The Sanction Monitoring software solutions are designed to streamline the compliance process, reduce the risk of financial crime, and ensure that banks adhere to global regulatory requirements related to sanctions, anti-money laundering (AML), and counter-terrorist financing (CTF) measures. It is essential to consider the Best Sanction Screening softwares that is adaptable to regulatory requirements.For best screening software for your financial  business Ixsight’s Sanction Screening Software is the best solution. Detect, prevent and manage sanctions risk by screening customers and transactions in real time and make appropriately compliant risk decisions. By using our Sanctions Monitoring software – Run periodic watchlist checks. Screen with PEP, AML & Sanction lists and protect your organization.

to know us-https://ixsight.com/products/sanctions-check/

[effiyatech]

Regulation change for payment aggregators

AML laws for payment aggregators have changed!    2023 requirements by RBI for payment aggregators now make it mandatory to:  - Develop and timely update KYC  - Conduct thorough due diligence and risk assessment of the merchants they onboard  - Develop Customer Acceptance policies  Monitor large transactions and submit transaction-related data to regulatory authorities as per the prescribed timelines and formats.   Keep and make available all customer information held with them.  Adherence to other AML and #counter-terrorism financing measures    Non-compliance with the new #regulations may lead to heavy penalties. To avoid the fines, payment aggregators are forced to make significant changes to their operations.    But for many of them these changes bring risks and expenses.    Majority of #AML related solutions have long implementation time and require programming professionals to install and operate them. Large volume of false positive alerts also forces businesses to spend on the investigation teams.   This is where Effiya solution can help you comply with ease:  Quick implementation  User interface for full control that doesn’t require programming skills  AI engine to reduce false positives.   For a demo, do email us on info@effiya.com

[zigram-tech]

Empower Your Business with Zigram's Comprehensive AML Risk Assessment Solutions

Enhance security with Zigram's advanced AML risk assessment services. Our tailored solutions, blending industry expertise and innovative technology, ensure seamless compliance. Trust us for thorough risk evaluation and resilient financial protection.

[namescan]

Anti money laundering CTF | NameScan

[fooltemps]

Leukemia and Lymphoma Awareness Flags!!

This flag was designed by us, as we currently have a family member with Leukemia and wish to bring awareness to this kind of cancer.

color meaning:

#FF2D34: Myeloma

#00DC0E: Non-Hodgkin Lymphoma

#FF8C2E: Leukemia

#D12DFF: Hodgkin Lymphoma

Below is information all about Leukemia and Lymphoma Cancers.

Leukemia and Lymphoma are both cancers that are not associated with a tumor. Lymphomas are cancers that affect the lymph system and start in cells called lymphocytes. Leukemia is a cancer of the early blood-forming tissues, including your bone marrow and lymph system.

There are many types of lymphoma. Some grow and spread slowly and some are more aggressive. There are two main types of Lymphoma:

1. Hodgkin Lymphoma is cancer that starts in the B lymphocytes (B cells) of the lymph system. Your lymph system helps you fight infection and control the fluids in your body.

2. Non-Hodgkin Lymphoma (NHL) is cancer that starts in the lymphocytes anywhere lymph tissue is found:

Lymph nodes

Spleen

Bone marrow

Thymus

Adenoids and tonsils, or

The digestive track.

Leukemia typically involves white blood cells, the cells that are your infection fighters. Leukemia can be divided into categories: fast growing (acute) and slow growing (chronic); and by which white blood cells are affected:

Acute lymphocytic leukemia (ALL)

Acute myelogenous leukemia (AML)

Chronic lymphocytic leukemia (CLL

Chronic myelogenous leukemia (CML)

A screening test is used to detect cancers in people who may be at higher risk for developing the disease. With leukemia and lymphoma, there are no early detection tests. The best way to find them is to be aware of the symptoms:

Swollen lymph nodes which can appear as a lump in the neck, armpit or groin;

Fever

Night sweats

Weight loss without trying, and

Fatigue.

Leukemia can have similar symptoms but also can include:

Easy bleeding or bruising;

Recurring nosebleeds; and

Bone pain or tenderness

Myeloma is cancer of the plasma cells. Plasma cells are white blood cells that produce disease- and infection-fighting antibodies in your body. Myeloma cells prevent the normal production of antibodies, leaving your body's immune system weakened and susceptible to infection. The multiplication of myeloma cells also interferes with the normal production and function of red and white blood cells. An abnormally high amount of these dysfunctional antibodies in the bloodstream can cause kidney damage. Additionally, the myeloma cells commonly produce substances that cause bone destruction, leading to bone pain and/or fractures.

Myeloma cells are produced in the bone marrow, the soft tissue inside your bones. Sometimes myeloma cells will travel through your blood stream and collect in other bones in your body. Because myeloma frequently occurs at many sites in the bone marrow, it is often referred to as multiple myeloma.

Signs and symptoms of myeloma include the following:

Hypercalcemia (excessive calcium in the blood)

Anemia (shortage or reduced function of red blood cells)

Renal damage (kidney failure)

Susceptibility to infection

Osteoporosis, bone pain, bone swelling, or fracture

High protein levels in the blood and/or urine

Weight loss

In 2022, more than 62,650 people are expected to be diagnosed with leukemia. In addition:

Leukemia accounts for 3.6% of all new cancer cases.

The overall 5-year survival rate for leukemia has more than quadrupled since 1960.

62.7% of leukemia patients survive 5 years or more.

The diagnosis of leukemia requires specific blood tests, including an examination of cells in the blood and marrow.

Treatment and prognosis depend on the type of blood cell affected and whether the leukemia is acute or chronic. Chemotherapy and blood and marrow transplant are often used to treat leukemia.

If you wish to read more about Leukemia and Lymphoma cancer, please visit this website!

[winguardaml]

The best AML compliance companies in Dubai, UAE.

[sandeep-trading]

What Are the Cash App Bitcoin Withdrawal or Purchase Limits and How to Increase Them?

Cash App, a popular mobile payment platform, has expanded its services to include cryptocurrency transactions. Users can buy, sell, and withdraw Bitcoin directly through the app. However, like most financial platforms, Cash App imposes specific limits on Bitcoin transactions. Understanding these limits and how to increase them is essential for maximizing your crypto trading and withdrawal potential.

What Are the Cash App Bitcoin Withdrawal Limits?

Cash App has clear guidelines for Cash App Bitcoin withdrawal limits, which ensure secure transactions and compliance with regulatory standards. Below is a breakdown of these limits:

Cash App Daily Bitcoin Withdrawal Limit: The current daily withdrawal limit for Bitcoin is $2,000. This cap applies to all withdrawals within a 24-hour period.

Cash App Weekly Bitcoin Withdrawal Limit: Users are restricted to a total Bitcoin withdrawal limit of $5,000 per week. This is calculated on a rolling 7-day basis, starting from the time of your first withdrawal in that period.

These limits include both completed and pending withdrawals. If you attempt to withdraw more than the allowed amount, your transaction will not be processed until you remain within the permitted limits.

What Are the Cash App Bitcoin Purchase Limits?

In addition to withdrawal limits, Cash App imposes purchase limits on Bitcoin transactions:

Cash App Daily Purchase Limit: Users can buy Bitcoin worth up to $10,000 per day through the app. This ensures that casual and professional investors can make significant transactions without exceeding the cap.

Cash App Weekly Purchase Limit: There is no separate weekly purchase cap, but the daily limit resets every 24 hours.

These limits make Cash App a practical tool for both small-scale and moderate cryptocurrency investors. However, higher purchase demands may require alternative strategies or platforms.

Why Does Cash App Impose Bitcoin Transaction Limits?

Cash App enforces transaction limits for several reasons, including:

Regulatory Compliance: These limits help Cash App comply with financial regulations related to anti-money laundering (AML) and know-your-customer (KYC) protocols.

User Security: Limits prevent potential fraud and unauthorized transactions, ensuring a secure environment for all users.

Platform Efficiency: By capping transactions, Cash App maintains its processing capabilities, even during peak transaction times.

How to Increase Cash App Bitcoin Withdrawal or Purchase Limits

If you frequently hit your Cash App limits or need higher caps for Bitcoin transactions, follow these steps to increase your Cash App Bitcoin Withdrawal limits:

1. Complete Your Identity Verification

Verification is crucial for increasing your transaction limits. Here’s how to verify your identity on Cash App:

Open the Cash App and navigate to the profile icon.

Select “Personal” from the menu.

Provide your full legal name, date of birth, and Social Security Number (SSN).

Follow the on-screen prompts to submit additional identification documents if required.

Once your identity is verified, you may notice an immediate increase in your Bitcoin withdrawal and purchase limits.

2. Enable Bitcoin Deposits and Withdrawals

To unlock the full potential of your Cash App Bitcoin limits, you must enable Bitcoin deposits and withdrawals. Follow these steps:

Go to your Bitcoin tab on the Cash App.

Select “Enable Withdrawals and Deposits”.

Provide any additional information or verification required by the app.

Enabling this feature ensures that you can fully utilize your Bitcoin transaction capabilities on Cash App.

3. Maintain a Positive Transaction History

Frequent and responsible transactions on Cash App may lead to higher limits over time. To build a strong transaction history:

Avoid canceled or failed transactions.

Ensure all payments and Bitcoin purchases comply with Cash App policies.

Use the app regularly for both personal and business purposes.

4. Contact Cash App Support

If your Bitcoin transaction needs exceed the standard limits, consider reaching out to Cash App’s customer support. You can explain your situation and request a custom limit increase. Be prepared to provide additional documentation or proof of income to support your request.

Tips for Managing Bitcoin Limits on Cash App

To make the most of your Bitcoin transactions on Cash App, keep the following tips in mind:

Plan Withdrawals Strategically: If you’re close to reaching your withdrawal limit, schedule your transactions to avoid delays.

Diversify Platforms: If Cash App’s limits do not meet your needs, consider using additional cryptocurrency platforms with higher caps.

Monitor Limit Changes: Cash App occasionally updates its policies. Regularly check your app for notifications about limit changes or promotions.

Common Issues and Troubleshooting

Users occasionally encounter issues when trying to withdraw or purchase Bitcoin on Cash App. Here’s how to address them:

Transaction Declined Due to Limits: Double-check your daily or weekly limits and ensure you’re not exceeding them.

Verification Delays: If your verification is taking longer than expected, ensure that all submitted documents are clear and meet the app’s requirements.

Pending Withdrawals: Large withdrawals may take additional time to process. Monitor the status of your transaction in the app.

Conclusion

Understanding Cash App Bitcoin withdrawal and purchase limits is essential for seamless cryptocurrency transactions. While these limits may initially seem restrictive, completing identity verification and building a solid transaction history can help you increase your caps. For those requiring even higher limits, contacting Cash App support can provide additional options.

[jcsmicasereports]

Acute Myeloid Leukemia In Pregnancy: Difficult Journey From Diagnosis To Delivery And Treatment by Vina Kumari in Journal of Clinical Case Reports Medical Images and Health Sciences

Abstract

The incidence of Acute Myeloid Leukemia in pregnancy is about 1 in 75,000 to 1 in 100,000. Owing to the therapy attributable risks to mother and fetus, the management of AML in pregnancy is very challenging, both for the parents and the medical fraternity. Furthermore, the diagnosis of leukemia in pregnancy is very difficult owing to vague presenting symptoms like fatigue and weakness which are confused with physiological changes during pregnancy.

Case Report: Primigravida, 33 weeks 6 days gestation age, with history of weakness and fatigue for 15 days and fever, cough and cold for 3 days was referred to our hospital with blood reports of raised total leucocyte count. The lab reports showed thrombocytopenia, anemia and leukocytosis with increased circulating blasts in the peripheral smear. As she was in her third trimester, plan of induction of labor and delivery followed by chemotherapy was taken. She delivered a live healthy baby. Post-delivery, she was advised chemotherapy. She had an immediate remission after the chemotherapy. The disease relapsed after 10 months and she succumbed to the disease due to unavailability of facilities during the COVID pandemic.

Conclusion: AML during pregnancy is rare. There is no fixed protocol for management of AML during pregnancy .The aim of management should be to take care of the initial concerns regarding fetal well-being according to gestation age and commence chemotherapy as soon as possible. This would give the best survival chances to the mother.

Keywords: Acute myeloid leukemia, pregnancy, chemotherapy.

Introduction

The association of leukemia and pregnancy is very rare, rather under-diagnosed and sparsely reported. The prevalence based on diagnosed and reported cases is one in 75,000 to 100,000 pregnancies. Most of the leukemias diagnosed in pregnancy are myeloblastic.

Acute myeloid leukemia (AML) is characterized by excessive proliferation of blast cells of myeloid lineage. This results in hematopoietic insufficiency like anemia and thrombocytopenia. The symptoms are related to complications of the pancytopenia, such as infections or hemorrhagic diathesis. The mentioned initial symptoms of leukemia in pregnancy are easily attributed to physiological changes related to the pregnancy and hence are either missed or diagnosed late. We report a case of Acute Myeloid Leukemia in a pregnant patient, its management and outcome.

Case Presentation

18-year-old primigravida presented at 33 weeks 6 days gestation. She was referred with history of weakness since 15 days and fever, cough, cold since 3 days associated with raised leucocyte count. She belonged to low socioeconomic status, was unbooked and had two antenatal visits during her pregnancy. She visited the facility when she had symptoms of gross weakness.

Her first trimester was uneventful. She was registered at a local hospital but was not compliant. Dating scan, trisomy screening and anomaly scan was not done.

On examination, her pulse rate was 88, blood pressure 100/60, respiratory rate 20 per minute, and temperature 99 degree Fahrenheit. She was pale but there was no jaundice, icterus or edema. She had angular stomatitis, and glossitis indicating malnutrition. Lymph nodes were not palpable.

On per abdomen examination, Uterus was relaxed, 33-34 weeks size and fetal heart 143/min. Ultrasound showed a single live fetus in cephalic presentation with effective fetal weight of 2.4 kg and liquor 12.7cm. Placenta was in upper posterior position. The fetus had overdistended urinary bladder with hydronephrosis of fetal kidneys suggestive of bladder outlet obstruction. Moderate hepatosplenomegaly was present. She was moderately anemic with hemoglobin of 8.3 gm/dl. The leucocyte count was very high 2,66,000/cu mm with neutrophils 4, lymphocytes 1, eosinophils 1 and basophils 1. The blood picture showed marked leucocytosis with blasts cells predominating 86% and 2 myelocytes and 1 metamyelocyte. The blast cells typically showed large nuclei, opened up chromatin, prominent nucleoli and cytoplasmic blebs. This picture raised the suspicion of Acute Myeloid Leukemia in pregnancy. Her platelet count was 96000/cu mm. LDH was raised 995 U/L signifying cell lysis. Liver enzymes were also borderline raised. Dengue serology was found negative. Her blood group was O negative. Serum Creatinine - 1.05 mg/dl and Serum uric acid - 10.9 mg/dl were also raised. The blood picture thus indicated towards normochromic normocytic anemia, thrombocytopenia and leukocytosis. On further examination of the peripheral blood smear, a leukoerythroblastic formula was noted with the presence of predominant blast population (86%).

Peripheral smear showed mostly Monoblasts (red arrow), promonocytes (green arrow) and few myeloblasts (blue arrow) under the oil immersion object 100 X, Leishman stain.

Monoblasts are large cells with abundant cytoplasm, moderately to intensely basophilic, scattered fine azurophilic granules, round nuclei with lacy chromatin and one or more large nucleoli.

Promonocytes have moderate cytoplasm, less basophilic, granulated with occasional large azurophilic granules. Vacuoles are more irregular. Nuclei are delicately folded.

Myeloblasts have large nuclei, fine chromatin, 3-4 prominent nucleoli and few Auer rods in the cytoplasm.

In view of suspected Acute Myeloid Leukemia, she was advised Bone marrow aspiration, biopsy and immunophenotyping, flow cytometry and translocation (15:17) study by oncologist.

The obstetrical examination was normal. All cardiotocographies were reactive. She was started on IV antibiotics, Inj Ceftriaxone 1 gm IV BD and steroids, Inj Betamethasone was given for fetal lung maturity. In view of malignancy with pregnancy, the case was discussed in tumor board on 10/9/19 and a decision for delivery followed by chemotherapy was taken.

She was induced with one dose of intracervical dinoprostone gel following which she went into labour and delivered live baby 2.8 kg weight with good apgar. The baby was shifted to nursery in view of premature delivery and mother was planned to transfer to medical oncology department for Induction chemotherapy.

Repeat investigations three days after delivery, haemoglobin decreased to 7 g/dl, TLC increased to 3,81,000 cells per cu mm with neutrophils 2, lymphocytes 5 and myelocytes 5. The abnormal blast cells had increased to 88% and platelets decreased to 21000 per cu mm (TABLE 1). Serum creatinine also increased to 1.43 mg/dl and e-GFR decreased to 54 ml/min/1.73 m2, indicating compromised renal function. The peripheral picture showed mostly agranuloblasts with moderate to scanty grey blue vacuolated cytoplasmic nuclei showing convolutions and 1-3 nucleoli occasional myelocytes, metamyelocytes seen, findings in favour of Acute myeloid leukemia (M4/M5). On myeloperoxidase staining, only 40 % took up the stain indicating AML-M4 lineage. She was transfused with one packed cell and one single donor platelet, following which her condition improved. She was transferred to medical oncology ward where she received chemotherapy and had immediate remission of the disease.

Discussion

The Incidence of Acute Myeloid Leukemia is 1 in 75,000 to 100,000 pregnancies with maximum 40% presenting in third trimester and 23% and 37% in first and second trimester respectively. In a population based study by Nolan et al [1], out of total acute leukaemia cases, two thirds are myeloblastic and one third lymphoblastic leukemia.

The rarity of disease during pregnancy, might also be due to very low reporting in view of confusing diagnosis. The symptoms of AML can easily be confused with symptoms of anaemia like malaise, easy fatigueability, low grade fever. Thrombocytopenia and anaemia are relatively common findings in pregnancy. Although, Neutropenia is rare and merits further investigation or close monitoring. But in the developing country like India, it is majorly missed. Thus, whenever there is presence of circulating blasts in a blood film, it suggests a diagnosis of haematological malignancy and is an indication for bone marrow biopsy. The other differential diagnosis that should be kept in mind are Thrombotic microangiopathy, HELLP syndrome and Cytopenias of deficiency or immune origin [2].

The tests to be done before bone marrow aspiration are Full blood count, blood film examination, Vitamin B12, folate and ferritin measurement, Coagulation screen, Renal and liver function tests. All these were done for our patient and further bone marrow aspiration was suggested with studies directed at Immunophenotypic, cytogenetic and molecular analysis for accurate subtyping and understanding of prognostic features.

Once diagnosed, a Multidisciplinary approach comprising of hematologists, obstetricians, anesthetists and neonatologists is the key to appropriate management. Consideration should be given to health of both mother and baby. The woman should be fully informed about the diagnosis, treatment of the disease and possible complications during pregnancy , clearly implying that any treatment delays might result in compromised maternal outcome without improving the outcome for the fetus [3].

The risks of Leukemia, disease per se, to pregnancy is miscarriage, foetal growth restriction, perinatal mortality, premature labour and Intrauterine fetal death [4].

Due to the high risk of the disease, there are different recommendations for management of AML in pregnancy in the three trimesters owing to the urgent need of chemotherapeutic agents and the adverse effects of the drugs involved .

If it is diagnosed in the first trimester, the patient should be counselled for elective abortion, medical/surgical and starting of chemotherapy. Between 13- 24 weeks, the Induction chemotherapy should be started while pregnancy is continued [5]. Preterm termination of pregnancy is indicated after fetal viability. Similar conclusions were derived by Nicola et al and Farhadfar in a single centre study of 5 and 23 case of AML diagnosed during pregnancy respectively [6,7].

Between 24 - 32 weeks, chemotherapy exposure to the fetus must be balanced against risks of prematurity following elective delivery at that stage of gestation (Grade 1C). At gestation age more than 32 weeks, the fetus should be delivered prior to Induction chemotherapy.

Chemotherapy with anthracycline based regimens are favored. According to a meta-analysis done by Natanel A Horowitz et al, anthracycline based regimens were associated with maximum remission but overall maternal survival was very low (30%)[8]. Even in our case, although the mother immediately had remission with chemotherapy. There was a recurrence after disease free 10 months and she succumbed to the disease during the COVID pandemic. Quinolones, tetracyclines and sulphonamides are better avoided in pregnancy(Grade 1B).

In one case report by Abdullah et al, a trial of 5- azacytidine has shown promising results [9]. The antifungal of choice in pregnancy is Amphotericin B or lipid derivatives (Grade 2C). If blood transfusion is needed, the blood should be screened for Cytomegalovirus (Grade 1B). Supportive therapy like a course of Corticosteroids given if delivery is between 24 and 35 weeks gestation (Grade 1A) [10]. Magnesium sulphate should be considered 24 h prior to delivery before 30 weeks gestation (Grade 1A).

Delivery should be planned for a time when the woman is at least 3 weeks post-chemotherapy to minimize risk of neonatal myelosuppresion (Grade 1C). Planned delivery is preferred, like Induction of labour (Grade 2C). Caesarean section is indicated only for obstetric indications. Epidural analgesia is better avoided.

The Dose of chemotherapy is calculated on their actual body weight with dose adjustments for weight gain during pregnancy owing to various pregnancy changes.

The Chemotherapy agents have a MW of 250-400 KDa and hence can cross the placenta resulting in detrimental teratogenic effects on developing fetus.Sunny J. Patel et al have done a comprehensive analysis on outcomes in hospitalized pregnant patients with acute myeloid leukemia and come to conclusion that a multidesciplinary, holistic approach leads to quick remission of the disease [11]

After delivery, histopathologic examination of placenta to rule out placental transfer to fetus is advisable. Cytologic examination should be performed in both maternal and umbilical cord blood and neonates should be clinically examined for palpable skin lesions, organomegaly or other masses. If the baby is found to be healthy, a follow up after every six months for two years is recommended. In each visit, physical examination, chest x-ray and liver function tests should be done.

Conclusion

Acute myeloid leukemia in pregnancy is a Rare diagnosis and even rarely reported. With the trend for delaying pregnancy into the later reproductive years, we expect to see more cases of cancer complicating pregnancy. Presently, there are no clear management guidelines to address timing and dosing of anthracycline/cytarabine based regimens especially in pregnancy. The potential drug toxicity to mother and fetus and transplant considerations in intermediate and highrisk patients during pregnancy has not been addressed.

What we also need today is a National registry for leukemia patients, treated in pregnancy. This will help us to answer many unanswered queries and improve maternal and fetal overall survival rates. Although we have few comprehensive studies, but further studies and references are needed. Finally, a Multidisciplinary team is needed to provide comprehensive care to patients.

[reginap5]

Five Tips for Enhancing Your KYC Compliance and AML Procedures

In today's rapidly evolving regulatory landscape, maintaining robust Know Your Customer (KYC) and Anti-Money Laundering (AML) compliance processes is more crucial than ever for businesses. These processes go beyond mere regulatory requirements; they form the cornerstone of secure operations, global expansion, customer trust, and data-driven insights. In this article, we'll delve into five essential tips to optimize your KYC processes and ensure AML compliance.

Understanding KYC and AML Compliance

KYC, short for Know Your Customer, refers to the practice of verifying and assessing the identities and risk levels of your customers. This procedure is vital for adhering to regulatory mandates and mitigating risks associated with financial crimes like money laundering and fraud. KYC plays a pivotal role in maintaining a secure business environment and building trust with clients.

Non-compliance with KYC regulations can lead to severe repercussions such as hefty fines, legal actions, reputational damage, and business disruptions. Therefore, adhering to KYC regulations is not just a necessity; it's a protective measure for your business.

1. Screening Against Current Lists

Efficient KYC begins with screening customers against relevant, up-to-date lists. Utilizing comprehensive KYC solutions equipped with advanced technology and access to databases containing sanction lists, politically exposed persons (PEPs) databases, and other watchlists enhances the accuracy of your screening processes.

By incorporating these KYC screening tools, you minimize risks and ensure compliance while reducing false positives, which ultimately saves valuable time and resources.

2. Integration with Risk Assessment

Integrating KYC into your broader risk assessment framework is crucial for maintaining an effective process. Customer information can change rapidly, necessitating continuous monitoring. Regularly reviewing and updating KYC data enables you to adapt to shifting risk profiles and make informed decisions.

Furthermore, integrating KYC data into your risk assessment facilitates a seamless link to ongoing due diligence processes. For instance, if a customer's risk profile changes due to a new business venture, you can proactively adjust your risk mitigation strategies.

3. Establishing Scalability

Keeping up with new clients and evolving compliance requirements requires a flexible and scalable KYC process. Onboarding new clients, regardless of their type, should be a consistent and streamlined process rather than a burden.

Investing in a scalable KYC solution capable of handling increasing data volumes and simplifying onboarding processes is key. Such a solution enables instant screening and efficient onboarding, allowing you to focus on growth without hindrances.

4. Preparing for Regulatory Challenges

The landscape of AML and KYC compliance is continually evolving, with regulators worldwide tightening their grip on financial institutions. Preparing for these challenges by embracing technology-driven KYC solutions can lead to automation, enhanced accuracy, and improved customer experiences.

Automated KYC solutions provide the means to avoid the hefty fines and regulatory scrutiny associated with non-compliance. Staying ahead of regulatory changes through technology-driven approaches is a strategic move for safeguarding your business.

5. Seeking Expert Assistance

In the face of complex regulatory requirements and the ever-changing landscape of AML and KYC compliance, seeking expert assistance can prove invaluable. Companies like KYC Sweden offer AML platforms that seamlessly integrate KYC responses with transaction monitoring.

This integration allows for quick identification of unusual transaction behavior, reducing the risk of being unwittingly involved in money laundering or terrorist financing. Outsourcing transaction monitoring to experts through a Managed Service can streamline your compliance efforts.

In conclusion, optimizing your KYC and AML processes is not only about regulatory compliance but also about safeguarding your business and fostering trust with clients. By following these five tips, incorporating technology-driven solutions, and staying prepared for regulatory changes, you can streamline your KYC and AML compliance, ensuring a secure and successful business journey.

Is your business prepared for the potential consequences of regulatory audits? Have you integrated transaction monitoring with your KYC processes? If you seek further guidance on these crucial matters, don't hesitate to contact us at KYC Sweden.

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Aml Monitoring Program - Aml Partners

What are the 4 components of AML program?

AML compliance software refers to technology solutions designed to help organizations comply with Anti-Money Laundering (AML) regulations and prevent financial crimes such as money laundering and terrorist financing. These software systems use various tools and functionalities to automate processes, monitor transactions, and flag suspicious activities within financial institutions.

Key features of AML compliance software may include:

Customer Due Diligence (CDD): Collecting and verifying customer information to assess the risk associated with each client.

Transaction Monitoring: Tracking and analyzing transactions in real-time to detect unusual or suspicious behavior.

Watchlist Screening: Checking customers against global watchlists to identify individuals or entities involved in illegal activities.

Reporting and Documentation: Generating reports and maintaining records to comply with regulatory requirements.

Risk Assessment: Evaluating and assigning risk levels to customers or transactions based on various parameters.

Automated Alerts: Notifying compliance officers of potential risks or suspicious activities for further investigation.

Integration Capabilities: Connecting with other systems or databases for seamless data sharing and analysis.

AML compliance software is crucial for financial institutions to meet regulatory obligations and mitigate the risks associated with financial crimes. These tools help streamline compliance processes, reduce manual errors, and enhance the overall effectiveness of AML efforts.