#albumin is what

[somuchtostudysolittletime]

ITU course expectation: that I will read 50 pages about fluids

ITU course reality: me googling “what is a colloid” because I don’t know anything about fluids let alone 50 pages of advanced fluids

[neonotoniawightii]

omegaverse niktyom where nikita is an omega who smells like the sweet subtone of decomposing trash and the sourness of teenage armpit sweat

[sonjabysonjamorgan]

ndjsjxndj i hate having too much medical knowledge it takes me out of medical shows (wtf does this giant rich hospital not have any resources beyond a dumbass resident and a chaplain for a maybe dying teen who’s worried about dying) but not enough medical knowledge to like. know what anything does.

[atomicstarburstlabware]

every day feels like i'm taking a couple of huge steps forwards at cost of at least half a dozen steps back (and just as many gaffes)

[harmeet-saggi]

Understanding Microalbumin Creatinine Ratio: A Comprehensive Guide To Kidney Health

Are you familiar with the microalbumin creatinine ratio, a crucial parameter in the world of kidney health? In this comprehensive guide, we will delve into the significance of this ratio, how it aids in evaluating kidney health, and its role in detecting early signs of kidney damage. We'll explore the normal ranges, its importance for individuals with conditions like diabetes or high blood pressure, and the straightforward formula for calculating it. Let's embark on a journey to understand how the microalbumin creatinine ratio plays a vital role in maintaining healthy kidneys.

[scientia-rex]

I also spend a lot of time trying to convince people to prevent problems, because prevention still works better than cures. Don't fucking smoke! I would instantly become the best doctor who ever lived if I could just convince all my patients to quit smoking. Avoid alcohol! Don't do meth! Don't do fentanyl! Things that are poisons will poison you in ways you understand, in the short term, but also ways you can't really understand until you've watched dozens of people die from it thirty years later, struggling to breathe from their COPD or weak and nauseated beyond bearing from their end-stage liver disease. I watched a man take 3 weeks in the ICU to die from what meth did to his heart. Your heart isn't meant to beat 145 times a minute for weeks on end. Your liver isn't meant to metabolize 5 shots of gin a day. You aren't going to be able to use denial and willpower to repair the damage your own habits did.

I drink a lot less now than I did before I went into medicine. Lot of different reasons, including that I'm older and more settled. But I can't look at it the same way I used to; I can't brush off as a "fun quirk" what I know is alcohol use on a level that risks withdrawal seizures if they were to suddenly stop, like some of my family members do, nervously asking me about their loved one's drinking when we're alone because beneath the jokes they know it's a problem.

If you're having more than one, maybe two drinks a day on average, over a long period of time, you are damaging your body in ways you don't understand. You're setting up a permanent heightened inflammatory state. Your heart cells don't like alcohol; Google "alcohol-induced cardiomyopathy." Your esophagus and stomach respond to incessant bathing in poison by first developing wounds and then cancer. Your liver, of course, doesn't like it. Your liver not only converts poisons to harmless substances you can excrete, it also makes your platelets, so your blood can clot. It makes albumin, a protein that's essentially for keeping water in your blood vessels and not letting it leach into your tissues. So people who are dying of liver failure are in pain and weak and tired and sad the whole fucking time! And the only solution, a liver transplant, will come with a lifetime of medication and specialist check-ups and the knowledge that if you fuck up and kill this liver, too, no one is going to be eager to give you another try.

I don't guilt-trip my alcoholic patients with liver disease. I don't guilt-trip my smokers with COPD. They chose to cope with substances for reasons, even if I disagree with their reasons, even if those reasons are opaque to me. They will suffer the natural consequences of those actions whether I guilt-trip them or not. I want them to continue to see me, I want them to be honest with me. Other people will lay enough guilt on them. And nothing I can say or do would ever compare to the physical and mental suffering that goes with those diseases.

But if you can prevent these diseases in yourself, prevent them. Quit smoking. Do it now. Your lungs are going to look better starting almost immediately, with positive changes continuing for many years. Drink less alcohol. Sure, it's fun, sure, it's a longstanding human tradition, but it is also unfortunately a straight up poison and your body knows that no matter how persuasively you argue about the obvious failure of Prohibition. You can't argue with a cell. You can't convince your kidneys that high blood pressure shouldn't damage them. They are a system; they do what they do; they existed long before prefrontal cortex existed to justify what we want to do but know to be harmful.



[spookyfluffy]

Jaiden might have had some "adult beverages" before showing up on BBH and Foolish's streams so here's some Drunk Jaiden shenanigans:

Confessed to metagaming because she watched BBH's stream to see how badly she messed up during the interrogation. She laughed at her accidentally messaging to Bad instead of Foolish and insisted (badly) she never lied.

Joined a game of making Pommè choose her favorite and told Pommè "Who should kill themselves in front of you? Pick now, quickly!"

Yelled "DAPPER" every time he showed up.

Tried to read Dapper's book of experiments AWFULLY and didn't know what albumin is ("all-boo-min"). Ended with "I did not absorb any of that."

Bad gaslighted her into thinking she's repeating herself after she told him she has bad memory.

Watched Foolish placed TNT to upset Pommè and immediately started pole dancing.

Used an elevator and went "Woah! It's like me but higher up!"

Saw a lion and asked Foolish "Have you seen the one where he's cooking crystal meth?"

"I think the biggest animal I could take on is a toddler."

"What if the rabbits stack on top of each other and they have a rabbit ladder?"

"Half of the rabbits attack you and half of them go bang. Which section do you attack first?"

[weirdmarioenemies]

Name: Barrel Bomb

Debut: Mario Kart Tour

I gotta be honest, all this time I thought this thing was just called Obstacle. That was much funnier to me. Is it ok if I start this post over and you all pretend its official name is Obstacle? Thank you so much.

Name: Obstacle

Debut: Mario Kart Tour

Yep. That sure is an Obstacle if I've ever seen one! They really named this thing Obstacle. I can't say I disagree! It has a bright red Bowser face, and best of all, its metal rims have spikes like the spiked bands Bowser wears. This barrel isn't just designed that way, it's wearing accessories! It's wearing spiked bands, and technically, it has a face, so I think Obstacle counts as a member of the Koopa Troop. It hangs out with them, and one day, hopes to maybe even drive a kart of its own...!

Obstacle is like the evil version of the DK Barrel. Donkey Kong? Now that guy is my funny friend. If one of HIS barrels is in the way, it's probably not too intrusive, and might even have goodies inside! It might also have him inside! Remember the recent confirmation that Kongs are not apes? That makes it more likely that wooden barrels are their eggs, and they are full of albumin. Be careful breaking them... you might be in for a Wet Surprise! Don't act like it's weird, Yoshi's whole brand is eggs and we let that happen!

Don't even think about crashing into Obstacle. You'll be obstructed if you do! Maybe you'd think "This obstacle is a bad guy and I should kill it by running it over with my car" (and you would have a point because this barrel is clearly the moral scum of the earth, quite frankly), but impact with Obstacle will cause you to Explode. It will also explode if it from afar with something such as a shell, which is utilized in some challenges to defeat large groups of Goombas. You might think Obstacle was just trying to hang out with the Goombas, but remember what an utterly reprehensible villain Obstacle is. I bet it stationed itself there on purpose, so that it could sacrifice itself to destroy its supposed friends. Irredeemable!

My favorite thing about Obstacle is that they are Bowser-branded at all, here in this game where Bowser and his cronies are playable. A Bowser face to communicate "Bad! Stay away!" when you could easily be playing as Bowser. It makes sense from a game design standpoint, but it's still silly! Obstacle will make no exception for its boss. Maybe the Koopa Kingdom is the most notable exporter of obstacles in the Mushroom World, and Bowser provides the Obstacles like BaNaNa Boy provides the bananas! He should have given them a better name, though. "Obstacle"? That's so vague!

[macgyvermedical]

Possibly(?) easy question if you're inclined: Beyond saline, are there some common IV nutrients/supplements a person might be likely to be given if they've been in a physically stressful situation for a while (where they haven't been able to take good care of themself/have lost some weight) and have now reached medical care but are going to need to be going into surgery in the near future?

We don't typically give nutrients IV. If a person can't use their mouth to eat we typically give them an NG tube into their stomach so we can give tube feed. If they can't use their whole digestive system, we might give TPN (total parenteral nutrition) via IV but TPN is somewhat dangerous and very expensive, so we'll exhaust a lot of options prior to this method.

What we might do is if the person has very low protein in their blood, we can give protein in the form of human albumin. It is important to have protein in the blood to both maintain blood pressure and to be able to use certain medications. Human albumin is a blood product, meaning it is derived from donated blood.

We may also give an IV solution called lactated ringers. This is kind of like an IV sports drink, and it replaces many lost electrolytes. If there are any particular electrolytes (like potassium or magnesium) that need replaced, those may also be given, either orally or in IV form.

[communist-manifesto-daily]

Socialism: Utopian and Scientific - Part 5

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Again, our agnostic admits that all our knowledge is based upon the information imparted to us by our senses. But, he adds, how do we know that our senses give us correct representations of the objects we perceive through them? And he proceeds to inform us that, whenever we speak of objects, or their qualities, of which he cannot know anything for certain, but merely the impressions which they have produced on his senses. Now, this line of reasoning seems undoubtedly hard to beat by mere argumentation. 

But before there was argumentation, there was action. Im Anfang war die That. [from Goethe's Faust: "In the beginning was the deed."] And human action had solved the difficulty long before human ingenuity invented it. The proof of the pudding is in the eating. From the moment we turn to our own use these objects, according to the qualities we perceive in them, we put to an infallible test the correctness or otherwise of our sense-perception. If these perceptions have been wrong, then our estimate of the use to which an object can be turned must also be wrong, and our attempt must fail. But, if we succeed in accomplishing our aim, if we find that the object does agree with our idea of it, and does answer the purpose we intended it for, then that is proof positive that our perceptions of it and of its qualities, so far, agree with reality outside ourselves. And, whenever we find ourselves face-to-face with a failure, then we generally are not long in making out the cause that made us fail; we find that the perception upon which we acted was either incomplete and superficial, or combined with the results of other perceptions in a way not warranted by them — what we call defective reasoning. So long as we take care to train our senses properly, and to keep our action within the limits prescribed by perceptions properly made and properly used, so long as we shall find that the result of our action proves the conformity of our perceptions with the objective nature of the things perceived. Not in one single instance, so far, have we been led to the conclusion that our sense-perception, scientifically controlled, induce in our minds ideas respecting the outer world that are, by their very nature, at variance with reality, or that there is an inherent incompatibility between the outer world and our sense- perceptions of it.

But then come the Neo-Kantian agnostics and say: We may correctly perceive the qualities of a thing, but we cannot by any sensible or mental process grasp the thing-in-itself. This "thing-in-itself" is beyond our ken. To this Hegel, long since, has replied: If you know all the qualities of a thing, you know the thing itself; nothing remains but the fact that the said thing exists without us; and, when your senses have taught you that fact, you have grasped the last remnant of the thing-in-itself, Kant's celebrated unknowable Ding an sich. To which it may be added that in Kant's time our knowledge of natural objects was indeed so fragmentary that he might well suspect, behind the little we knew about each of them, a mysterious "thing-in- itself". But one after another these ungraspable things have been grasped, analyzed, and, what is more, reproduced by the giant progress of science; and what we can produce we certainly cannot consider as unknowable. To the chemistry of the first half of this century, organic substances were such mysterious object; now we learn to build them up one after another from their chemical elements without the aid of organic processes. Modern chemists declare that as soon as the chemical constitution of no-matter-what body is known, it can be built up from its elements. We are still far from knowing the constitution of the highest organic substances, the albuminous bodies; but there is no reason why we should not, if only after centuries, arrive at the knowledge and, armed with it, produce artificial albumen. But, if we arrive at that, we shall at the same time have produced organic life, for life, from its lowest to its highest forms, is but the normal mode of existence of albuminous bodies.

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[reality-detective]

In the first 6 years of life your child receives the following through vaccines:

•17,500 mcg 2-phenoxyethanol (antifreeze)

•5,700 mcg aluminum (neurotoxin)

•Unknown amounts of fetal bovine serum(aborted cow blood)

•801.6 mcg formaldehyde (carcinogen, embalming agent)

•23,250 mcg gelatin (ground up animal carcass)

•500 mcg human albumin (human blood)

•760 mcg of monosodium L-glutamate (causes obesity & diabetes)

•Unknown amounts of MRC-5 cells (aborted human babies)

•Over 10 mcg neomycin (antibiotic)

•Over 0.075 mcg polymyxin B (antibiotic)

•Over 560 mcg polysorbate 80 (carcinogen)

•116 mcg potassium chloride (used in a lethal injection)

•188 mcg potassium phosphate (liquid fertilizer agent)

•260 mcg sodium bicarbonate (baking soda)

•70 mcg sodium borate (Borax, used for cockroach control)

•54,100 mcg of sodium chloride (table salt)

•Unknown amounts of sodium citrate (food additive)

•Unknown amounts of sodium hydroxide (Danger! Corrosive)

•2,800 mcg sodium phosphate (toxic to any organism)

•Unknown amounts of sodium phosphate monobasic monohydrate (toxic to any organism)

•32,000 mcg sorbitol (Not to be injected)

•0.6 mcg streptomycin (antibiotic)

•Over 40,000 mcg sucrose (cane sugar)

•35,000 mcg yeast protein (fungus)

•5,000 mcg urea (metabolic waste from human urine)

•Other chemical residuals

(From the book, "What The Pharmaceutical Companies Don't Want You To Know About Vaccines" - By Dr.Todd M. Elsner)

Let this sink in. 🤔

[erose-this-name]

Every Time a Bell Rings

Cult of the Lamb Ficlet

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It had been a long night serving at the drinkhouse for the yellow-furred cat follower (of varying name). He is behind on getting everything cleaned and shut down for the day.

Then the Lamb happens to walk by, yawns, and picks up a mop. Their favorite, eldritch mop.

The yellow cat says, “Leader, it’s fine, really, I can handle this on my own.”

“And yet, you have my help.” The Lamb smiles.

If the yellow cat has learned anything about his leader, it’s that they’re not the kind to delegate. If they see something that needs doing, they just do it. No matter how dirty. This is starkly contrast to every other crown bearer he’s ever heard of.

The bell around the Lamb’s neck rings with each push of their mop.

“Leader, I hope you don’t mind my asking, but why are you always wearing that bell?” The yellow cat asks.

“Huh? Oh, I’m sorry, it’s not annoying, is it? I suppose I could change into another fleece…” Lamb says.

Yellow cat says, “No, no! Not at all. Actually, it's nice to hear you’re near, makes me feel safe. It’s just, I mean, a lot of us have been wondering why you wear it? Isn’t it annoying for you?”

“Oh, baahaahaa! Yeah, I guess it’s not a very ‘fashionable’ accessory, is it?” The Lamb laughs.

Somehow the thought people would question the bell has never crossed the sheep's mind. They goes back to mopping, their brow furrowing slightly.

“Um, so when I was very young, I used to crawl all over the place. You know how babies do that. And, my parents were afraid I’d wander too far and, uh… attract the Bishops to our hidden refuge. So they put the bell on me. So they’d always know where I was. Even when I got old enough to not need it, when I understood… it just kind of felt wrong if a bell doesn’t ring with every step, you know? I was so used to it.” They say.

The cult leader has been absentmindedly moping and mopping the same patch of floor well past the point of spotless.

The Lamb holds the base of the bell and rings it in their hand. Its tinkling sound rings clearly. “I find it calming.”

Yellow Cat sees that several other faint children’s names had been crudely engraved into the base of that old, dinged up bell, then scratched out. Each name’s marks are increasingly worn down and filled with tarnish. The last name has had every letter except L-A-M-B scratched off, in their place are marks fresh enough to still expose raw shiny brass beneath the layers of patina.

SHEPHERD RAMSES BOPEEP COSSETTE LAMBERT

The feline follower’s expression had been steadily falling through the whole story. “Oh, right. Of course… I’m sorry I asked, Leader.”

The Lamb puts on a half smile and coquettishly tilts their head to the side. ��Don’t worry about it. Also, the collar keeps my head from falling off.”

"Huh?"

⋅∴∵∴∵∴∵⁂∵∴∵∴∵∴⋅

One day, many days later, Leshy and that same yellow furred cat he hangs around barge into the Lamb’s office.

The yellow cat stutters, face turning more red than yellow. “Hey, Leader, so… um…”

Leshy cuts off yellow cat, “I have utilized this lowly cat’s perfect genes to mother a demigod heir to rival your tyranny, foul Lamb.”

Leshy holds up an egg. It is the cult’s first birth.

The Lamb stares, at a loss for words, “What?… an *egg*? I thought you’re both male? Didn’t you just… HOW?”

“Do not underestimate the power of my clitellum, small-minded mammal!” Says the green earthworm.

The yellow cat mumbles, traumatized, “I didn’t even realize we were having sex that way, worms are so weird…”

⋅∴∵∴∵∴∵⁂∵∴∵∴∵∴⋅

The egg is about to hatch. Yellow Cat, Leshy, Lamb, Shamura, Kallamar, Narinder, and Heket have gathered around to watch.

Kallamar delivers the baby and, despite being a potent source of slime himself, he recoils at the albumin and viscera.

Yellow Cat and Lamb are the only one’s to greet the new life with smiles, everyone else grimaces at the hideous abomination of nature. Except for Leshy and Shamura, who have no idea what’s happening.

Leshy asks, “Well? Is it mighty? DOES IT HAVE MY TEETH?” 

Kallamar wrinkles his lack of a nose, “It’s… uh, I mean, I guess it is healthy, but…”

Narinder says, “It’s an ‘it’, alright. Aym and Baal were much cuter kits.”

“SACRILEGIOUS BEAST, GIVE ME THE RED CROWN, SO I MAY SEE MY CHILD THROUGH IT!” The horned worm leaps at the Lamb, trying to wrestle the Red Crown away from them.

“NEVER! IT’S MINE! MY PRECIOUS!” The woolly God of Death roars as they push the ex-god off them. Narinder rolls his eyes.

Yellow cat says, nervously, “They’re… I mean, I love them, and they’re a perfect ball of joy… but…”

“WON’T SOMEONE TELL ME HOW OUR CHILD LOOKS?!” Leshy cries.

“… ugly…” Heket croaks.

Leshy falls to his knees, “NOOOOOOO!”

Yellow cat turns to the Lamb and gently hands the baby to them.

“Leader, we talked it over, and we thought it’d be best if you name it.” Yellow cat says.

The Lamb smiles, “I’d be honored to-”

“Wait, no, what were you thinking, cat? GET AWAY FROM MY DEMIGOD, GOD-MURDERER! Godparent Shamura, you shall name it!” Leshy commands.

The ex-chaos bishop rips the infant away from the Lamb and thrusts it into Shamura’s arms, who is about as surprised as everyone else.

The concussed spider looks down at their new niece/nephew, cradling it in two of their arms while gently wrapping it in a silk swaddle with another two. Tiny malformed fingers wrap around a thin chitinous thumb.

Shamura mumbles, “Hmm… Yes. I see you, lowliest worm, just begun. Becoming our moon, yet you reached for the sun. Zero becomes one becomes two. You are named ‘Metztli’, aren’t you? She has your eyes, Leshy. And my thumb.”

The yellow cat smiles, “‘Metztli’, what a beautiful name. Leshy, your eye looked like that? They’re so pretty!”

⋅∴∵∴∵∴∵⁂∵∴∵∴∵∴⋅

Several days later, after returning from an impromptu crusade, Lamb knocks on Leshy and the yellow cat’s door. They are greeted by the cat.

The Lamb says, “Hello! I have a gift for Meztli… uh, Metzi? Mets-klee-”

“Metztli?” The cat corrects.

Lamb nods, “Yes, that. I can speak in tongues, how do you do that?”

The Lamb gives the yellow cat a small box. The feline follower opens it to find a single fine golden bell on a soft ribbon necklace. It is expertly engraved with the name Metztli.

Lamb says, their own bell jingling, “I’ve been worrying about her… I just wanted to keep her safe.”

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[murky-tannin]

Dapper's Hemomancy notes

Dapper also said Bad's blood wasn't human, but that's hardly news.

Transcription of the text under cut!

dapper's hemomancy notes: I have seen dad and the others leak this red liquid, they call it blood. apparently they share composition with that of villagers. I also found some practical uses for it. its quite rich in materials. I can use it

so Albumin is the protein inside eggs that work as a binding agent in baking. an egg has 4.225 grams of albumin. a liter of human blood has around 35-50 grams. if we use 42.5 as a middle point we get that we need 99.4 millimeters of blood to replace an egg

if the standard adult male has between 5 or 6 liters of blood. if we round it to 5.5 and we again say it has an albumin content of 42.5 grams per liter, a person can replace about 553 eggs with a Margin of error of about 50 eggs depending on the amount of blood volume it has

Human bodies have iron, mainly in the blood. a standard european longsword weights 1.2 to 1.8 kilos so rounding it to 1.6 kilos, in about 5.5 liters of standard blood we can find 3.5 to 4.5 grams of blood, so we round it up to 4 since there is about 0.45 grams per liter.

all of this means we would need the blood of 3556 people to make a european Iongsword that weights 1.6 kilos

Chlorine and sodium are also part of the human's blood, and its also part of what they know as table salt. due to molecular masses in a kilo of table salt we would have about 607 grams of chlorine and 393 grams of sodium. a liter of blood has 3.545 grams of chlorine and about

3.2206 grams of sodium. this means that you would need 171.44 liters of human blood to reach the required chlorine and in it you would already have the 122.1 liters required to reach the amount of sodium required for the kilo of table salt.

I have realized human's blood also contain phosphorus, I remember using it in matches. a box of matches of say 30 matches of bad quality so of about 1 gram of phosphorus each. and in the case that you are able to do allotropy to convert the white phosphorus from human's blood

into the required red phosphorus for matches (which is apparently a 1 to 1 conversation due to laws of conservation of mass). now in a liter of human blood you can find about 0.25 to 0.45 milligrams of human blood so we round it to 0.35 milligrams. now if we want to make the box

of matches from it we would need about 85,714.29 liters of human blood to get enough phosphorus for 30 mediocre matches. this is without counting the igniting stick as I dont know the standard length of those to calculate them aswell. I need more research

[pippindot]

Lots of good vibes for Pip please. Her tummy is still getting bigger. She does not seem uncomfortable, and is in fact currently begging me for breakfast, but I don't like to see this increase. I'm suspicious this is actually a result of her very low protein diet, as she's having no other symptoms of liver distress. We all need some protein to build albumin, and albumin is what keeps your fluid inside your blood vessels. Low albumin means leaky vessels means ascites. There are some other liver formulations out there with slightly higher protein, so we might climb the scale. The main goal of low protein is to avoid neurological symptoms, and we haven't had any of those, so it should be safe to try. Nutrition consult tomorrow and I hope they're ready for the freight train.

Worst case, I may bip my little self on over to their ER and get some diuretics for her. The timing is very poor since we are traveling for Boofest, but at least we are going to be in an area with a lot of specialty services.

Most of all, she seems in good spirits and is not having any trouble breathing. Let's hope this is temporary and won't require long term medication to manage. I want to preserve her kidneys as much as we can.

[sonjabysonjamorgan]

actually speaking of albumin last time i went to a resident and told them to correct their order bc what they wrote won’t fly w the blood bank they were like “oh sure, i don’t rly think albumin does anything anyways so whatever” and i was like okay cool! i can’t tell if that was crazy or not or like u should not be in medicine crazy or just somewhat radical theory crazy

[willowreader]

Story out! An albumin fused ACE2 design that blocks all SARS-CoV-2 variants. The design has a long plasma half-life and can be delivered in a needle-free manner across mucosal surfaces.

This is fantastic news. A COVID blocker is exactly what we need.