#W. J. T. Mitchell

[melissande]

ESTO ESTABA EN LA DIAPOSITIVA 4

Peter Wagner condena

que se siga enfatizando la diferencia de lo que,

en esencia,

son sistemas de signos

(ya sea verbales o visuales).

E insiste en que es posible

estudiar su estructura retórica común.

W. J. T. Mitchell dice que

todas las artes son artes compuestas

(texto e imagen);

todos los medios son medios mezclados.

[southernmermaidsgrotto]

Herbalism book reccomendations 📚🌿

General herbalism:

The Herbal Medicine-Maker's Handbook by Green J. (2011)

20,000 Secrets of Tea: The Most Effective Ways to Benefit from Nature's Healing Herbs by Zak V. (1999)

The Modern Herbal Dispensatory: A Medicine-Making Guid by Easly T. (2016)

A-Z Guide to Drug-Herb-Vitamin Interactions by Gaby A.R.

American Herbal Products Association's Botanical Safety Handbook (2013) 

Medical Herbalism: The Science and Practice of Herbal Medicine by Hoffman D. (2003)

Herbal Medicine for Beginners: Your Guide to Healing Common Ailments with 35 Medicinal Herbs by Swift K & Midura R (2018)

Today's Herbal Health: The Essential Reference Guide by Tenney L. (1983)

Today's Herbal Health for Women: The Modern Woman's Natural Health Guide by Tenney L (1996)

Today's Herbal Health for Children: A Comprehensive Guide to Understanding Nutrition and Herbal Medicine for Children by Tenney L. (1996)

For my black folks!!!

African Medicine: A Complete Guide to Yoruba Healing Science and African Herbal Remedies by Sawandi T.M. (2017)

Handbook of African Medicinal Plants by Iwu M.M. (1993)

Working The Roots: Over 400 Years of Traditional African American Healing by Lee M.E. (2017)

Hoodoo Medicine: Gullah Herbal Remedies by Mitchell F. (2011)

African American Slave Medicine: Herbal and non-Herbal Treatments by Covey H.C. (2008)

The Art & Practice of Spiritual Herbalism: Transform, Heal, and Remember with the Power of Plants and Ancestral Medicine by Rose K.M. (2022)

Indigenous authors & perspectives!!

Braiding Sweetgrass: Indigenous Wisdom, Scientific Knowledge and the Teachings of Plants by Kimmerer R.W. (2015)

Gathering moss by Kimmerer R.W. (2003)

The Plants Have So Much To Give All We Have To Do Is Ask by Siisip Geniusz M. (2005)

Our Knowledge Is Not Primitive: Decolonizing Botanical Anishinaabe Teachings by Djinn Geniusz W. (2009)

Ancient Pathways, Ancestral Knowledge: ethnobotany and ecological wisdom of indigenous peoples of northwestern North America by Turner N. (2014)

A Taste of Heritage: Crow Indian Recipes and Herbal Medicines by Hogan Snell A. (2006)

Medicines to Help Us by Belcourt C. (2007)

After the First Full Moon in April: A Sourcebook of Herbal Medicine from a California Indian Elder by Grant Peters J. (2010)

Latin american herbalism works!!

Earth Medicines: Ancestral Wisdom, Healing Recipes, and Wellness Rituals from a Curandera by Cocotzin Ruiz F. (2021)

Hierbas y plantas curativas by Chiti J.F. (2015)

Del cuerpo a las raíces by San Martín P.P., Cheuquelaf I. & Cerpa C. (2011)

Manual introductorio a la Ginecología Natural by San Martín P.P.

🌿This is what I have for now but I’ll update the post as I find and read new works, so keep coming if you wanna check for updates. Thank you for reading 🌿

[cheddar-baby]

Hi there cheery baby, I've read Barthes & Sontag's books on photography. Any suggestions on who I should read next?

What Do Pictures Want? The Lives and Loves of Images by W. J. T. Mitchell

Criticizing Photographs: An Introduction to Understanding Images by Terry Barrett

Not specifically photo theory but

The Queer Art of Failure

by Jack Halberstam

I havent made it through this one yet fully cause it was a tough read but what i have read and parsed was really good stuff

The Work of Art in the Age of Mechanical Reproduction. By Walter Benjamin

[compneuropapers]

Interesting Papers for Week 32, 2024

In and Out of Criticality? State-Dependent Scaling in the Rat Visual Cortex. Castro, D. M., Feliciano, T., de Vasconcelos, N. A. P., Soares-Cunha, C., Coimbra, B., Rodrigues, A. J., … Copelli, M. (2024). PRX Life, 2(2), 023008.

An event-termination cue causes perceived time to dilate. Choe, S., & Kwon, O.-S. (2024). Psychonomic Bulletin & Review, 31(2), 659–669.

Stimulus-dependent differences in cortical versus subcortical contributions to visual detection in mice. Cone, J. J., Mitchell, A. O., Parker, R. K., & Maunsell, J. H. R. (2024). Current Biology, 34(9), 1940-1952.e5.

Sexually dimorphic control of affective state processing and empathic behaviors. Fang, S., Luo, Z., Wei, Z., Qin, Y., Zheng, J., Zhang, H., … Li, B. (2024). Neuron, 112(9), 1498-1517.e8.

Post-retrieval stress impairs subsequent memory depending on hippocampal memory trace reinstatement during reactivation. Heinbockel, H., Wagner, A. D., & Schwabe, L. (2024). Science Advances, 10(18).

An effect that counts: Temporally contiguous action effect enhances motor performance. Karsh, N., Ahmad, Z., Erez, F., & Hadad, B.-S. (2024). Psychonomic Bulletin & Review, 31(2), 897–905.

Learning enhances representations of taste-guided decisions in the mouse gustatory insular cortex. Kogan, J. F., & Fontanini, A. (2024). Current Biology, 34(9), 1880-1892.e5.

Babbling opens the sensory phase for imitative vocal learning. Leitão, A., & Gahr, M. (2024). Proceedings of the National Academy of Sciences, 121(18), e2312323121.

Information flow between motor cortex and striatum reverses during skill learning. Lemke, S. M., Celotto, M., Maffulli, R., Ganguly, K., & Panzeri, S. (2024). Current Biology, 34(9), 1831-1843.e7.

Statistically inferred neuronal connections in subsampled neural networks strongly correlate with spike train covariances. Liang, T., & Brinkman, B. A. W. (2024). Physical Review E, 109(4), 044404.

Pre-acquired Functional Connectivity Predicts Choice Inconsistency. Madar, A., Kurtz-David, V., Hakim, A., Levy, D. J., & Tavor, I. (2024). Journal of Neuroscience, 44(18), e0453232024.

Alpha-band sensory entrainment improves audiovisual temporal acuity. Marsicano, G., Bertini, C., & Ronconi, L. (2024). Psychonomic Bulletin & Review, 31(2), 874–885.

Excitability mediates allocation of pre-configured ensembles to a hippocampal engram supporting contextual conditioned threat in mice. Mocle, A. J., Ramsaran, A. I., Jacob, A. D., Rashid, A. J., Luchetti, A., Tran, L. M., … Josselyn, S. A. (2024). Neuron, 112(9), 1487-1497.e6.

Incidentally encoded temporal associations produce priming in implicit memory. Mundorf, A. M. D., Uitvlugt, M. G., & Healey, M. K. (2024). Psychonomic Bulletin & Review, 31(2), 761–771.

Intrinsic and Synaptic Contributions to Repetitive Spiking in Dentate Granule Cells. Shu, W.-C., & Jackson, M. B. (2024). Journal of Neuroscience, 44(18), e0716232024.

Dynamic prediction of goal location by coordinated representation of prefrontal-hippocampal theta sequences. Wang, Y., Wang, X., Wang, L., Zheng, L., Meng, S., Zhu, N., … Ming, D. (2024). Current Biology, 34(9), 1866-1879.e6.

Calibrating Bayesian Decoders of Neural Spiking Activity. Wei 魏赣超, G., Tajik Mansouri زینب تاجیک منصوری, Z., Wang 王晓婧, X., & Stevenson, I. H. (2024). Journal of Neuroscience, 44(18), e2158232024.

Attribute amnesia as a product of experience-dependent encoding. Yan, N., & Anderson, B. A. (2024). Psychonomic Bulletin & Review, 31(2), 772–780.

A common format for representing spatial location in visual and motor working memory. Yousif, S. R., Forrence, A. D., & McDougle, S. D. (2024). Psychonomic Bulletin & Review, 31(2), 697–707.

Unified control of temporal and spatial scales of sensorimotor behavior through neuromodulation of short-term synaptic plasticity. Zhou, S., & Buonomano, D. V. (2024). Science Advances, 10(18).

[aftermidnightfmk]

Guests

Part 2: April 11, 2024 to July 22, 2024

Tumblr limits posts to 100 links, thus the necessity of splitting of the Guests page into parts. It is inconvenient, yes. Click here for a list of all parts.

Alphabetical by last name, unless they don't have a surname, in which case, good luck.

Looking for the host? Try the Taylor Tomlinson tag.

Is a name misspelled? Link broken? Dear god, please tell me.

Please note: “kill” choices are (usually) not tagged. Therefore the links below may not be inclusive of every guest’s appearance on After Midnight.

A

Alaska 5000

Utkarsh Ambudkar

Marcella Arguello

Scott Aukerman

B

Todd Barry

Kimia Behpoornia

BenDeLaCreme

Doug Benson

Hannah Berner

Mike Birbiglia

Ashley Nicole Black

Katherine Blanford

Flula Borg

John Ross Bowie

Guy Branum

C

Drew Carey

Catherine Cohen

Sherry Cola

Michelle Collins

Kelsey Cook

Stephanie Courtney

Terry Crews

D

Rhys Darby

James Davis

Lori Beth Denberg

Debra DiGiovanni

Colton Dunn

E

Alex Edelman

Rich Eisen

Mary Elizabeth Ellis

Felipe Esparza

F

Nat Faxon

Chris Fleming

Daniel Franzese

G

Ana Gasteyer

Solomon Georgio

Zach Gilford

Lisa Gilroy

Eliot Glazer

Leo González

Brandon Kyle Goodman

Patty Guggenheim

Harvey Guillen

H

Dave Hill

Chloé Hilliard

Dave Holmes

Pete Holmes

Sandy Honig

I

J

Aaron Jackson

Gillian Jacobs

Penn Jillette

Jay Jurden

K

Moshe Kasher

Echo Kellum

Laurie Kilmartin

Jessica Kirson

Hari Kondabolu

Bert Kreischer

L

Thomas Lennon

Joe Lo Truglio

Jon Lovett

Jessica Lowe

M

Aasif Mandvi

Joe Manganiello

Joe Mantegna

Jack McBrayer

Jess McKenna

Heather McMahan

Kate Micucci

Liz Miele

Kel Mitchell

Mandy Moore

Laci Mosley

Morgan Murphy

N

Aparna Nancherla

Kevin Nealon

O

Atsuko Okatsuka

Patton Oswalt

P

Adam Pally

Punam Patel

Johnny Pemberton

Eddie Pepitone

Q

R

Diona Reasonover

Laura Ramoso

Franchesca Ramsey

Jim Rash

Chris Redd

Pat Regan

Caitlin Reilly

Andy Richter

Jason Ritter

S

Kristen Schaal

Reid Scott

Rory Scovel

Josh Sharp

Timothy Simons

Brian Simpson

Jason Sklar

Randy Sklar

Blair Socci

Betsy Sodaro

Chris Sullivan

T

Carl Tart

Danny Tamberelli

Chrissy Teigen

Sarah Tiana

Jackie Tohn

Steph Tolev

Paul F. Tompkins

U

Jenna Ushkowitz

V

Milana Vayntrub

Baron Vaughn

W

Lisa Ann Walter

Sydnee Washington

Michaela Watkins

X

Y

"Weird Al" Yankovic

Bassem Youssef

Z

Sasheer Zamata

98/100

[hollow-triad]

Bleach’s Trilingual Voice Cast - Quincies

[Karakura Town]

Masaki Kurosaki (🇯🇵: Sayaka Ohara // 🇺🇸: Ellyn Stern) Masaki Kurosaki "Young" (🇯🇵: Sayaka Ohara // 🇺🇸: Cherami Leigh)

Uryū Ishida (🇯🇵: Noriaki Sugiyama // 🇺🇸: Derek Stephen Prince) Uryū Ishida "Young" (🇯🇵: Takako Honda)

Sōken Ishida (🇯🇵: Eiji Maruyama // 🇺🇸: David Lodge -> Liam O'Brien)

Old Man Getsu (🇯🇵: Takayuki Sugo // 🇺🇸: Richard Epcar)

Ryūken Ishida (🇯🇵: Ken Narita // 🇺🇸: Michael McConnohie -> Christopher Swindle)

Izumi Ishida (🇯🇵: Rei Igarashi // 🇺🇸: Karen Strassman)

Kanae Katagiri (🇯🇵: Mamiko Noto // 🇺🇸: Megan Hollingshead)

[Wandenreich]

[A] Yhwach (🇺🇸: Richard Epcar)

[B] Jugram Haschwalth (🇺🇸: Robbie Daymond)

[J] Quilge Opie (Xander Mobus)

[H] Bazz-B (🇺🇸: Xander Mobus)

[O] Driscoll Berci (🇺🇸: Bill Butts)

[D] Askin Nakk Le Vaar (🇺🇸: Daman Mills)

[N] Robert Accutrone (🇺🇸: Neil Kaplan)

[E] Bambietta Basterbine (🇺🇸: Anne Yatco)

[F] Äs Nödt (🇺🇸: Elijah Ungvary)

[U] NaNaNa Najahkoop (🇺🇸: Zeno Robinson)

[K] BG9 (🇺🇸: Aaron LaPlante)

[W] Nianzol Weizol (🇺🇸: Robbie Daymond)

[I] Cang-Du (🇺🇸: Landon McDonald)

[S] Mask De Masculine (🇺🇸: Bill Butts)

[L] PePe Waccabrada (🇺🇸: Zeno Robinson)

[P] Meninas McAllon (🇺🇸: Anne Yatco)

[R] Jerome Guizbatt (🇺🇸: Todd Haberkorn)

[Q] Berenice Gabrielli (🇺🇸: X)

[Y] Loyd Lloyd & Royd Llyod (🇺🇸: Robbie Daymond)

[?] Shaz Domino (🇺🇸: X)

[Z] Giselle Gewelle (🇺🇸: Casey Mongillo)

[X] Lille Barro (🇺🇸: Evan Michael Lee)

[M] Gerard Valkyrie (🇺🇸: Dave B. Mitchell)

[C] Pernida Parnkgjas (🇺🇸: X)

[T] Candice Catnipp (🇺🇸: Shara Kirby)

[L] Liltotto Lamperd (🇺🇸: Cherami Leigh)

[?] James (🇺🇸: Christopher Swindle)

[V] Gremmy Thoumeaux (🇺🇸: AJ Beckles)

(🇯🇵: X // 🇺🇸: X) (🇯🇵: X // 🇲🇽: X) X (🇺🇸: X)

[ranochjart]

disclaimer: de nombreux avatars datent de 2018-2019, je les poste si jamais ils peuvent toujours intéresser

A

aaron taylor johnson

alexander o'connor

alex hogh andersen

alycia debnam carey

ana de armas

ariana grande

aron piper

ashton sanders

B

billie eilish

brie larson

C

calvin harris

camille rowe

carlson young

chord overstreet

christopher briney

cole sprouse

D

dakota fanning

domhnall gleeson

dominic harrison

E

F

G

george mckay

H

halston sage

hande erçel

harry styles

hunter schafer

I

J

jack falahee

jackson wang

james lafferty

jennifer lawrence

jessica alba

julian morris

K

kiera knightley

kim jennie

kim taehyung

L

laetitia casta

lana del rey

lee taemin

lily james

lim bora

M

madison beer

magdalena zalejska

maia mitchell

matthew daddario

miles teller

N

nadia tereszkiewicz

nicolas peltz

O

P

philip froissant

phoebe tonkin

plan rathavit

Q

R

rafael lazzini

rain spencer

S

salem mitchell

saoirse ronan

T

tia jonsson

tom hardy

tom holland

U

ursula corbero

V

victoria lee

vinnie woolston

W

X

Y

Z

zayn malik

[tomsland]

TOMSLAND'S FC MASTERLIST

Aloha! He decidido hacer este FC Masterlist en lugar de una muse page porque durante 10 años de rol tuve más niños que una guardería. A continuación encontrarán faceclaims que he roleado/roleo/me gustaría rolear. Los escritos en negrita son personajes ya creados y el icono de estrella señala a mis musas principales, pero siéntanse libre de pedirme a quién sea que tengan como wanted opposite porque me abundan las ganas de rolearlos a todos.

A

Adelaide Kane

Alexandra Park (Eleanor Henstridge - Canon)

Alexis Ren

Alycia Debnam Carey (Saoirse Townes - OC) ★

Ana de Armas

Ariana Grande (Arielle Pavlak - OC)

Ashley Frangipane "Halsey" (Gemma Lovegood - OC)

B

Barbara Palvin (Sophie Blackwood - OC)

Bella Hadid

Bill Skarsgard

Britt Robertson

C

Candice Accola

Chace Crawford

Charlie Cox (Matthew Murdock - Canon / AU )

Chloe Bennet (Daisy Johnson - OC )

Chris Evans (Oliver Cohen - OC )

Chris Wood (Diego Casillas - OC) ★

D

Daniel Gillies (Ezra Sofianos - OC)

Danielle Campbell

Diego Boneta

Dylan O'Brien

E

Elizabeth Olsen (Winter Snow - OC)

Emeraude Toubia

Emilia Clarke

Emily VanCamp

Emma Roberts

Eugenia Suarez (Fernanda Acosta - OC)

Evan Peters

F

Francisco Lachowski

G

Gigi Hadid

Grant Gustin (Barry Allen - Canon / AU)

H

Halston Sage

Harry Styles ( Andrew Levine - OC ) ★

Henry Cavill (Louis Graham - OC)

I

Ian Somerhalder

J

Jack Falahee (Santiago Cardona - OC)

Jennifer Lawrence

Jensen Ackles (Zane Davenport)

Joe Jonas ( Jose Alejandro - OC )

Joseph Morgan ( James Black - OC ) ★

Josh Dallas

K

Katherine Mcnamara (Isis Sofianos - OC)

Kendall Jenner

Kylie Jenner

L

Lauren Jauregui ( Olivia Waldorf - OC )

Leighton Meester ( Brooklyn Swarovski - OC )

Liam Payne (Carter Disney - OC)

Lily Collins (Rosie Dunne - Canon )

Lily James

Louis Tomlinson (Thomas Crawford - OC)

Luke Hemmings (Blake Parker - OC) ★

M

Marie Avgeropoulos

Martin Garrix (Matthew Hale - OC)

Michael Fassbender

N

Niall Horan (Demian Ramsay - OC)

Nick Jonas

Nicola Peltz (Darcy Styles - OC )

Nina Dobrev

O

P

R

Richard Madden (William Hilton - OC) ★★

Riley Voelkel

S

Scott Eastwood (Lucas Prescott - OC)

Sebastian Stan ( Alexander Yasikov - OC)

Selena Gomez (Reign Carrington - OC)

Sophie Turner

Shay Mitchell (Chantelle Cooper - OC)

T

Tom Austen (Jasper Frost - Canon )

Tom Hardy (Jim Westminster - OC )

Tom Hiddleston

Tom Holland (Harry Gallagher - OC)

U

V

W

Y

Z

Zayn Malik (Nicholas Stronghold - OC)

[wolfanddragon98]

SCREAM ALPHABET (SCARLETT MITCHELL EDITION)!

@dreaming-for-an-escape​

A is for Attention

Are people looking at her differently after they learn what she had experienced in her hometown?

B is for Book 

What did she think about Gale’s book?

C is for College

How well did she settle in at college?

D is for Defense

After her encounters with the killers did she start learning defense?

E is for Equipment

What is one unexpected equipment that she used to fight off Ghostface?

F is for Fear

What is her biggest fear?

G is for Grief

How does she handle grief?

H is for Husband

Over the years, how well does she get along with Randy?

I is for Injuries

Are there any major injuries that she sustained? 

J is for Jamie

How is her relationship like with Jamie?

K is for Killer

Out of all the killers, which killer had traumatized her the most? 

L is for Location

Does she often move locations with her family because she fears for their safety or does she settle in one place that feels safe to her?

M is for Movies

What is her favourite scary movie?

N is for News

How up to date is she with the news that cover crime/murder cases?

O is for Occupation

Is she content with her current occupation?

P is for Phone Call

When does she receive her first Ghostface phone call?

Q is for Questions

Was there ever a question that she always wanted to ask one of the killers or their victims, but never had the chance to ask it?

R is for Rules

What is one horror movie rule to that she always sticks to no matter what?

S is for Stab

Did she see the Stab movies?

T is for Trauma

Which event caused her the biggest trauma?

U is for Unhinged

Were there ever moments where she felt like she was losing her mind?

V is for Vengeance

Did she ever feel the urge to go after someone who hurt her or her loved ones?

W is for Weapon 

What is her typical weapon of choice?

X is for X-Ray

Any broken bones?

Y is for Yearning

What is one thing that she always yearns for after experiencing those tragic events?

Z is for Zzz

How well does she sleep after the events?

[oniria-rpg]

APERTURAS DE LAS RESERVAS

Las reservas se abrirán oficialmente el día 30 (domingo) a las 18:30 hora peninsular española.

Las pautas para las reservas son las siguientes:

Únicamente puede reservarse un arquetipo por usuario.

Algunos arquetipos tienen condiciones especiales. Hay que respetarlas o este podrá ser retirado.

El máximo de reservas de FCs es de dos y de uso propio. No se pueden reservar rostros para búsquedas (en el foro tampoco es viable).

Los rangos que tienen un límite (cinco plazas) son los siguientes: estrategas, constructores y exploradores.

El máximo de diferencia de edad entre el faceclaim y el personaje es de seis años.

Las reservas durarán 96 horas, a partir del momento que se abra el foro, a menos que nos notifiquéis complicaciones, imprevistos, etcétera.

Formulario OBLIGATORIO de reserva:

Nombre del faceclaim + arquetipo + rango — apodo de reserva — contraseña (no la publicaremos)

*Los apartados que no reservéis eliminadlos.

RESERVAS VARIAS

Arquetipos reservados:

El apostador — Nike

El bibliotecario — King

El científico — techno

El del barrio — Gengis Kan

El derrotista — JinxPoe

El hiperactivo — Fregona con patas

El líder — Sam

El manitas — Cinder

El mercenario — ElDorado

El mujeriego — Astronauta

El positivo — LadyM

El temerario — JD

El veterano — Pistachito

La constructora - Midnight rain

La muñeca rusa — Straw

La recién llegada — Ficus

Ocho — Acht

Cupos de rangos limitados:

Estrategas (5/5):

BlackRose

Calcetín

ElDorado

Navegante

Sammie

Ya no hay más cupos

Constructores (5/5):

Astronauta

Midnight Rain

Nefelibata

Techno

Maryse

Ya no hay más cupos

Exploradores (5/5):

Benoit

Cinder

JD

King

Britt

Ya no hay más cupos

RESERVAS DE FACECLAIM

A B C

Adria Arjona — BlackRose

Alina Olesheva — Pepita

Ana de Armas — Pompeii

Anya Taylor Joy — Straw

Barry Keoghan — Sam

Blanca Soler — Midnight Rain

Ben Barnes (PNJ)

Brad Pitt (PNJ)

Charleen Weiss — Chrissy

Charlie Hunnam — Cinder

Choi Soobin — Gengis Kan

Chris Woods — Frost

D E F

Danny Griffin — Pepito Personajez

Daria Sidorchuk — Gasps in spanish

David Castañeda — ElDorado

Do KyungSoo — techno

Édgar Ramírez — Red

Eiza González — LadyM

Elisabeth Olsen — Damara

Elissa Bibaud — Nike

Elle Fanning — Ficus

Emily Deschanel — DetectiveMittens

Finn Wolfhard — Silver Star

Freddy Carter — Acht

G H I J

Grace Van Die — Astronauta

Harvey Guillen — Nefelibata

Henry Cavil — Yennefer

Helena Bonham Carter (PNJ)

Jeffrey Dean Morgan — ElDorado

K L M N Ñ

Karl Urban — Peppa Pig

Keanu Reeves — Pikmina

Lindsey Morgan — Poison

Mads Mikkelsen — Pistachito

Marta Piekarz — Bolifacio

Matthew Daddario — JD

Mia Goth — Brit

Natasha Lyonne   — Piedra

Nicholas Skidmore — Benoit

O P Q R

Olivia Cooke — Maryse

Pedro Pascal — King

Robert Mitchell — Calcetín

Robert Pattinson — JinxPoe

Ruby Rose — Skylar

S T U

Samara Weaving — Sammie

Scarlet Leithold — Alenna

Scott Eastwood — Fregona con patas

Sherouk Farid — Pompeii

Sophia Carson — Midnight Rain

Tanner Reese — Calcetín

V W X Y Z

[ulkaralakbarova]

A blind Vietnam vet, trained as a swordfighter, comes to America and helps to rescue the son of a fellow soldier. Credits: TheMovieDb. Film Cast: Nick Parker: Rutger Hauer Frank Devereaux: Terry O’Quinn Billy Devereaux: Brandon Call Cobb: Charles Cooper MacCready: Noble Willingham Annie Winchester: Lisa Blount Lynn Devereaux: Meg Foster The Assassin: Sho Kosugi Slag: Randall “Tex” Cobb Lyle Pike: Nick Cassavetes Tector Pike: Rick Overton Latin Girl: Julia González Gang Leader: Paul James Vasquez Crooked Miami Cop #1: Woody Watson Crooked Miami Cop #2: Alex Morris Bus Station Cop: Mark Fickert Popcorn: Weasel Forshaw Six Pack: Roy Morgan Snow: Tim Mateer Female Biker: C.K. McFarland Cornfield Killer #1: T.J. McFarland Cornfiled Killer #2: Blue Deckert Cornfield Killer #3: Glenn Lampert Cornfield Killer #4: Red Mitchell Rockwell Mom: Bonnie Suggs Rockwell Dad: Harold Suggs Freeway Lady #1: Barbara Gulling-Goff Freeway Lady #3: Holly Cross Vagley Freeway Lady #2: Dorothy Young Colleen: Sharon Shackelford Casino Bodyguard #1: Jay Pennison Casino Bodyguard #2: Masanori Toguchi Crooked Croupier: R. Nelson Brown Croupier #2: Lincoln Casey Jr. Croupier #3: Gene Skillen Big Mama: Debora Williams Casino Cowboy: Kyle Thatcher Casino Patron: Patricia Mathews Waiter in Elevator: Mitch Hrushowy Penthouse Guard #1: Ernest Mack Penthouse Guard #2: Linwood Walker Drug Dealer: Robert Prentiss Ski Lodge Killer #1: Jeffrey J. Dashnaw Ski Lodge Killer #2: Glenn R. Wilder Ski Lodge Killer #3: David R. Ellis Ski Lodge Killer #4: Michael Adams Ski Lodge Killer #5: Dave Bartholomew Ski Lodge Killer #6: Fred Lerner Ski Lodge Killer #7: Mike Shanks Ski Lodge Killer #8: Ray Colbert Film Crew: Director of Photography: Don Burgess Executive Producer: Robert W. Cort Producer: Daniel Grodnik Director: Phillip Noyce Producer: Tim Matheson Executive Producer: David Madden Associate Producer: Charles Robert Carner Production Design: Peter Murton Editor: David A. Simmons Original Music Composer: J. Peter Robinson Location Manager: Carole Fontana Unit Production Manager: Dennis Stuart Murphy Location Scout: Mike Harrowing Set Designer: Lauren E. Polizzi Title Designer: Michael Lodge Costume Design: Katherine Dover Production Coordinator: Jeffrey J. Kiehlbauch Casting Assistant: Louise Marrufo Production Coordinator: Gina Scheerer Casting: Junie Lowry-Johnson Casting Associate: William A. Johnson Art Direction: John Myhre Casting Assistant: Elisa Goodman Location Manager: Susan Elkins Script Supervisor: Helen Caldwell Set Decoration: Tom Talbert Second Unit Director: Dick Ziker Key Makeup Artist: Karoly Balazs Special Effects Makeup Artist: J.C. Matalon Assistant Hairstylist: Jan Sebastian Key Makeup Artist: Jeanne Van Phue Hairstylist: Cinzia Zanetti Production Manager: Leonard Bram Executive In Charge Of Production: Ted Zachary Additional Second Assistant Director: Sandy Collister Second Assistant Director: K.C. Colwell First Assistant Director: Tom Davies Second Assistant Director: Douglas Dean III Second Assistant Director: Thomas A. Irvine First Assistant Director: Donald P.H. Eaton Second Unit Director: Max Kleven Set Dresser: Joel Bestrop Art Direction: Michael Marcus Set Decoration: Nicholas T. Preovolos Sound Editor: Gregg Baxter Production Sound Mixer: Jacob Goldstein Assistant Sound Editor: David Hagberg Sound Re-Recording Mixer: Grover B. Helsley Sound Editor: Michael Hilkene Sound Mixer: Walter Hoylman Sound Editor: David M. Ice Sound Editor: Doug Jackson Special Sound Effects: Eric Lindemann Sound Re-Recording Mixer: William L. McCaughey Boom Operator: Prometheus Patient ADR Editor: Tally Paulos Foley Mixer: Troy Porter Sound Re-Recording Mixer: Richard D. Rogers Foley Artist: Joan Rowe Sound Editor: Christopher Sheldon Assistant Sound Editor: Thomas W. Small Foley Artist: Jerry Trent Special Effects Coordinator: Martin Bresin Special Effects Assistant: Steven C. Foster Special Effects Assistant: Marvin Gardner Special Effects Coordinator: Allen Hall Special Effects Supervisor: Mike Manzel Special Effects Assistant: Joe Montenegr...

[identity-library]

Diverse Sexuality (Films)

A:

B:

Beauty and The Beast (2017)

LeFou (Gay)

Brokeback Mountain (2005)

Ennis del Mar (Unspecified MLM)

Jack Twist (Unspecified MLM)

C:

D:

E:

F:

G:

H:

Home for the Holidays (1995)

Tommy Larson (Gay)

I:

J:

Jungle Cruise (2021)

McGregor Houghton (Gay)

K:

L:

Lightyear (2022)

Alisha Hawthorne (Lesbian)

M:

Marvel Cinematic Universe (Franchise)

America Chavez (Lesbian)

Aneka (Lesbian)

Ayo (Lesbian)

Korg (Gay)

Loki (Bisexual)

Mister Immortal (Bisexual)

Phastos (Gay)

Valkyrie (Bisexual)

Wade Wilson/Deadpool (Pansexual)

Miraculous World: New York - United Heroez (2020)

Barbara Keynes (Unspecified WLW)

Olympia Hill (Unspecified WLW)

N:

Nimona (2023)

Ambrosius Goldenloin (Gay)

Ballister Boldheart (Gay)

O:

Onward (2020)

Specter (Lesbian)

P:

Paranorman (2012)

Mitchell George "Mitch" Downe (Unspecified MLM)

Q:

R:

S:

Strange World (2022)

Ethan Clade (Gay)

T:

The New Mutants (2020)

Dani Moonstar (Lesbian)

Rahne Sinclair (Lesbian)

The Mitchells vs. The Machines (2021)

Katie Mitchell (Lesbian)

The Old Guard (2020)

Nicolò "Nicky" di Genova (Gay)

Yusuf "Joe" al-Kaysani (Gay)

U:

V:

W:

X:

Y:

Z:

[jcmarchi]

Accelerating CAR T cell therapy: Lipid nanoparticles speed up manufacturing - Technology Org

New Post has been published on https://thedigitalinsider.com/accelerating-car-t-cell-therapy-lipid-nanoparticles-speed-up-manufacturing-technology-org/

Accelerating CAR T cell therapy: Lipid nanoparticles speed up manufacturing - Technology Org

For patients with certain types of cancer, CAR T cell therapy has been nothing short of life-changing. Developed in part by Carl June, Richard W. Vague Professor at Penn Medicine, and approved by the Food and Drug Administration (FDA) in 2017, CAR T cell therapy mobilizes patients’ own immune systems to fight lymphoma and leukemia, among other cancers.

Using activating lipid nanoparticles (aLNPs) to create CAR T cells requires fewer steps and less time.

However, the process for manufacturing CAR T cells itself is time-consuming and costly, requiring multiple steps over days. The state-of-the-art involves extracting patients’ T cells, then activating them with tiny magnetic beads, before giving the T cells genetic instructions to make chimeric antigen receptors (CARs), the specialized receptors that help T cells eliminate cancer cells.

Now, Penn Engineers have developed a novel method for manufacturing CAR T cells, one that takes just 24 hours and requires only one step. This method uses lipid nanoparticles (LNPs), the potent delivery vehicles that played a critical role in the Moderna and Pfizer-BioNTech COVID-19 vaccines.

In a new paper in Advanced Materials, Michael J. Mitchell, Associate Professor in Bioengineering, describes the creation of “activating lipid nanoparticles” (aLNPs), which can activate T cells and deliver the genetic instructions for CARs in a single step, greatly simplifying  the CAR T cell manufacturing process. “We wanted to combine these two extremely promising areas of research,” says Ann Metzloff, a doctoral student and NSF Graduate Research Fellow in the Mitchell lab and the paper’s lead author. “How could we apply lipid nanoparticles to CAR T cell therapy?”

In some ways, T cells function like a military reserve unit: in times of health, they remain inactive, but when they detect pathogens, they mobilize, rapidly expanding their numbers before turning to face the threat. Cancer poses a unique challenge to this defense strategy. Since cancer cells are the body’s own, T cells don’t automatically treat cancer as dangerous, hence the need to first “activate” T cells and deliver cancer-detecting CARs in CAR T cell therapy.

Until now, the most efficient means of activating T cells has been to extract them from a patient’s bloodstream and then mix those cells with magnetic beads attached to specific antibodies — molecules that provoke an immune response. “The beads are expensive,” says Metzloff. “They also need to be removed with a magnet before you can clinically administer the T cells. However, in doing so, you actually lose a lot of the T cells, too.”

Made primarily of lipids, the same water-repellent molecules that constitute household cooking fats like butter and olive oil, lipid nanoparticles have proven tremendously effective at delivering delicate molecular payloads. Their capsule-like shape can enclose and protect mRNA, which provides instructions for cells to manufacture proteins. Due to the widespread use of the COVID-19 vaccines, says Metzloff, “The safety and efficacy of lipid nanoparticles has been shown in billions of people around the world.”

To incorporate LNPs into the production of CAR T cells, Metzloff and Mitchell wondered if it might be possible to attach the activating antibodies used on the magnetic beads directly to the surface of the LNPs. Employing LNPs this way, they thought, might make it possible to eliminate the need for activating beads in the production process altogether. “This is novel,” says Metzloff, “because we’re using lipid nanoparticles not just to deliver mRNA encoding CARs, but also to initiate an advantageous activation state.”

Over the course of two years, Metzloff carefully optimized the design of the aLNPs. One of the primary challenges was to find the right ratio of one antibody to another. “There were a lot of choices to make,” Metzloff recalls, “since this hadn’t been done before.”

By attaching the antibodies directly to LNPs, the researchers were able to reduce the number of steps involved in the process of manufacturing CAR T cells from three to one, and to halve the time required, from 48 hours to just 24 hours. “This will hopefully have a transformative effect on the process for manufacturing CAR T cells,” says Mitchell. “It currently takes so much time to make them, and thus they are not accessible to many patients around the world who need them.”

CAR T cells manufactured using aLNPs have yet to be tested in humans, but in mouse models, CAR T cells created using the process described in the paper had a significant effect on leukemia, reducing the size of tumors, thereby demonstrating the feasibility of the technology.

Metzloff also sees additional potential for aLNPs. “I think aLNPs could be explored more broadly as a platform to deliver other cargoes to T cells,” she says. “We demonstrated in this paper one specific clinical application, but lipid nanoparticles can be used to encapsulate lots of different things: proteins, different types of mRNA. The aLNPs have broad potential utility for T cell cancer therapy as a whole, beyond this one mRNA CAR T cell application that we’ve shown here.”

Source: University of Pennsylvania

You can offer your link to a page which is relevant to the topic of this post.

[lboogie1906]

The Tuskegee Airmen were a group of African-American and Caribbean-born military pilots who fought in WWII. They formed the 332nd Fighter Group and the 477th Bombardment Group of the Army Air Forces. The name applies to the navigators, bombardiers, mechanics, instructors, crew chiefs, nurses, cooks, and other support personnel.

All African American military pilots who trained in the US trained at Moton Field, the Tuskegee Army Air Field, and were educated at Tuskegee University. The group included five Haitians from the Haitian Air Force and one pilot from Trinidad. It included a Hispanic or Latino airman born in the Dominican Republic.

March 22, 1942 - The first five cadets graduate from the Tuskegee Flying School: Captain Benjamin O. Davis, Jr. and Second Lieutenants Mac Ross,

Charles DeBow, L.R. Curtis, and George S. Roberts. They will become part of my the famous 99th Pursuit Squadron. List of Tuskegge Airmen.

Paul Adams (pilot)

Rutherford H. Adkins

Halbert Alexander

William Armstrong

Lee Archer

Robert Ashby

William Bartley

Howard Baugh

Henry Cabot Lodge Bohler

George L. Brown

Harold Brown

Roscoe Brown

Victor W. Butler

William Burden

William A. Campbell

Herbert Carter

Raymond Cassagnol

Eugene Calvin Cheatham Jr.

Herbert V. Clark

Granville C. Coggs

Thomas T.J. Collins

Milton Crenchaw

Woodrow Crockett

Lemuel R. Custis

Floyd J. Crawthon Jr

Doodie Head

Clarence Dart

Alfonza W. Davis

Benjamin O. Davis Jr. (C/O)

Charles DeBow

Wilfred DeFour

Gene Derricotte

Lawrence Dickson

Charles W. Dryden

John Ellis Edwards

Leslie Edwards Jr.

Thomas Ellis

Joseph Elsberry

Leavie Farro Jr

James Clayton Flowers

Julius Freeman

Robert Friend (pilot)

William J. Faulkner Jr.

Joseph Gomer

Alfred Gorham

Oliver Goodall

Garry Fuller

James H. Harvey

Donald A. Hawkins

Kenneth R. Hawkins

Raymond V. Haysbert

Percy Heath

Maycie Herrington

Mitchell Higginbotham

William Lee Hill

Esteban Hotesse

George Hudson Jr.

Lincoln Hudson

George J. Iles

Eugene B. Jackson

Daniel "Chappie" James Jr.

Alexander Jefferson

Buford A. Johnson

Herman A. Johnson

Theodore Johnson

Celestus King III

James Johnson Kelly

James B. Knighten

Erwin B. Lawrence Jr.

Clarence D. Lester

Theodore Lumpkin Jr

John Lyle

Hiram Mann

Walter Manning

Robert L. Martin

Armour G. McDaniel

Charles McGee

Faythe A. McGinnis

John "Mule" Miles

John Mosley

Fitzroy Newsum

Norman L Northcross

Noel F. Parrish

Alix Pasquet

Wendell O. Pruitt

Louis R. Purnell Sr.

Wallace P. Reed

William E. Rice

Eugene J. Richardson, Jr.

George S. Roberts

Lawrence E. Roberts

Isaiah Edward Robinson Jr.

Willie Rogers

Mac Ross

Robert Searcy

David Showell

Wilmeth Sidat-Singh

Eugene Smith

Calvin J. Spann

Vernon Sport

Lowell Steward

Harry Stewart, Jr.

Charles "Chuck" Stone Jr.

Percy Sutton

Alva Temple

Roger Terry

Lucius Theus

Edward L. Toppins

Robert B. Tresville

Andrew D. Turner

Herbert Thorpe

Richard Thorpe

Thomas Franklin Vaughns

Virgil Richardson

William Harold Walker

Spann Watson

Luke J. Weathers, Jr.

Sherman W. White

Malvin "Mal" Whitfield

James T. Wiley

Oscar Lawton Wilkerson

Henry Wise Jr.

Kenneth Wofford

Coleman Young

Perry H. Young Jr.

#africanhistory365 #africanexcellence

[compneuropapers]

Interesting Papers for Week 12, 2024

Neural representation of goal direction in the monarch butterfly brain. Beetz, M. J., Kraus, C., & el Jundi, B. (2023). Nature Communications, 14, 5859.

The scope and role of deduction in infant cognition. Bohus, K. A., Cesana-Arlotti, N., Martín-Salguero, A., & Bonatti, L. L. (2023). Current Biology, 33(18), 4014-4020.e5.

Increasing associative plasticity in temporo-occipital back-projections improves visual perception of emotions. Borgomaneri, S., Zanon, M., Di Luzio, P., Cataneo, A., Arcara, G., Romei, V., … Avenanti, A. (2023). Nature Communications, 14, 5720.

Dopamine and glutamate regulate striatal acetylcholine in decision-making. Chantranupong, L., Beron, C. C., Zimmer, J. A., Wen, M. J., Wang, W., & Sabatini, B. L. (2023). Nature, 621(7979), 577–585.

Perturbed Information Processing Complexity in Experimental Epilepsy. Clawson, W., Waked, B., Madec, T., Ghestem, A., Quilichini, P. P., Battaglia, D., & Bernard, C. (2023). Journal of Neuroscience, 43(38), 6573–6587.

Common population codes produce extremely nonlinear neural manifolds. De, A., & Chaudhuri, R. (2023). Proceedings of the National Academy of Sciences, 120(39), e2305853120.

Dimensionality reduction reveals separate translation and rotation populations in the zebrafish hindbrain. Feierstein, C. E., de Goeij, M. H. M., Ostrovsky, A. D., Laborde, A., Portugues, R., Orger, M. B., & Machens, C. K. (2023). Current Biology, 33(18), 3911-3925.e6.

Information-theoretic principles in incremental language production. Futrell, R. (2023). Proceedings of the National Academy of Sciences, 120(39), e2220593120.

Echoes from Intrinsic Connectivity Networks in the Subcortex. Groot, J. M., Miletic, S., Isherwood, S. J. S., Tse, D. H. Y., Habli, S., Håberg, A. K., … Mittner, M. (2023). Journal of Neuroscience, 43(39), 6609–6618.

Intrinsic dopamine and acetylcholine dynamics in the striatum of mice. Krok, A. C., Maltese, M., Mistry, P., Miao, X., Li, Y., & Tritsch, N. X. (2023). Nature, 621(7979), 543–549.

Multiple dynamic interactions from basal ganglia direct and indirect pathways mediate action selection. Li, H., & Jin, X. (2023). eLife, 12, e87644.3.

Internal feedback in the cortical perception–action loop enables fast and accurate behavior. Li, J. S., Sarma, A. A., Sejnowski, T. J., & Doyle, J. C. (2023). Proceedings of the National Academy of Sciences, 120(39), e2300445120.

A role for ocular dominance in binocular integration. Mitchell, B. A., Carlson, B. M., Westerberg, J. A., Cox, M. A., & Maier, A. (2023). Current Biology, 33(18), 3884-3895.e5.

The representation of occluded image regions in area V1 of monkeys and humans. Papale, P., Wang, F., Morgan, A. T., Chen, X., Gilhuis, A., Petro, L. S., … Self, M. W. (2023). Current Biology, 33(18), 3865-3871.e3.

Switching between External and Internal Attention in Hippocampal Networks. Poskanzer, C., & Aly, M. (2023). Journal of Neuroscience, 43(38), 6538–6552.

Reward expectations direct learning and drive operant matching in Drosophila. Rajagopalan, A. E., Darshan, R., Hibbard, K. L., Fitzgerald, J. E., & Turner, G. C. (2023). Proceedings of the National Academy of Sciences, 120(39), e2221415120.

Engram stability and maturation during systems consolidation. Refaeli, R., Kreisel, T., Groysman, M., Adamsky, A., & Goshen, I. (2023). Current Biology, 33(18), 3942-3950.e3.

Different rules for binocular combination of luminance flicker in cortical and subcortical pathways. Segala, F. G., Bruno, A., Martin, J. T., Aung, M. T., Wade, A. R., & Baker, D. H. (2023). eLife, 12, e87048.3.

Anatomical restructuring of a lateralized neural circuit during associative learning by asymmetric insulin signaling. Tang, L. T. H., Lee, G. A., Cook, S. J., Ho, J., Potter, C. C., & Bülow, H. E. (2023). Current Biology, 33(18), 3835-3850.e6.

Robust multisensory deviance detection in the mouse parietal associative area. Van Derveer, A. B., Ross, J. M., & Hamm, J. P. (2023). Current Biology, 33(18), 3969-3976.e4.

[aftermidnightfmk]

Guests

Part 1: January 16, 2025 through April 10, 2024

Tumblr limits posts to 100 links, thus the necessity of splitting of the Guests page into parts. It is inconvenient, yes. Click here for a list of all parts.

Alphabetical by last name, unless they don't have a surname, in which case, good luck.

Looking for the host? Try the Taylor Tomlinson tag.

Is a name misspelled? Link broken? Dear god, please tell me.

Please note: “kill” choices are (usually) not tagged. Therefore the links below may not be inclusive of every guest’s appearance on After Midnight.

A

Marcella Arguello

B

Maria Bamford

Suzi Barrett

W. Kamau Bell

Doug Benson

Ashley Nicole Black

Flula Borg

Wayne Brady

Guy Branum

Matt Braunger

Kurt Braunohler

Sophie Buddle

C

Reggie Conquest

Kelsey Cook

Affion Crockett

Whitney Cummings

D

Jon Daly

Chad Daniels

James Davis

Bianca Del Rio

E

Billy Eichner

F

Jackie Fabulous

Fortune Feimster

Jourdain Fisher

Chris Fleming

Ron Funches

G

Jon Gabrus

Megan Gailey

Lisa Gilroy

Vanessa Gonzalez

Chris Grace

Max Greenfield

H

Rob Haze

John Hodgman

Robby Hoffman

Pete Holmes

Sandy Honig

Rob Huebel

London Hughes

Brendan Hunt

I

J

Josh Johnson

Joyelle Nicole Johnson

Zainab Johnson

Anjelah Johnson-Reyes

K

Amir K

Moshe Kasher

Jackie Kashian

Laurie Kilmartin

Joel Kim Booster

Kyle Kinane

Nick Kocher

Nish Kumar

L

Lauren Lapkus

Natasha Leggero

Thomas Lennon

Dan Levy

Riki Lindhome

Loni Love

M

Marc Maron

Jack Martin

Mae Martin

Brian McElhaney

Wendi McLendon-Covey

Liz Miele

Will Miles

Amy Miller

Kel Mitchell

Arden Myrin

N

Aparna Nancherla

Purple Necktie

Dustin Nickerson

Tig Notaro

O

Jerry O'Connell

Atsuko Okatsuka

Taylor Ortega

Haley Joel Osment

P

Adam Pally

Caitlin Peluffo

Dewayne Perkins

Pink Foxx

Esther Povitsky

Jeff Probst

Q

R

Chloe Radcliffe

Mary Lynn Rajskub

Adam Ray

Caroline Rhea

Rob Riggle

Phoebe Robinson

Matt Rogers

Giulia Rozzi

S

Nico Santos

Anna Seregina

Jason Sklar

Randy Sklar

Dusty Slay

Dulcé Sloan

Kevin Smith

Blair Socci

Beth Stelling

T

Carl Tart

Jordan Temple

Chris Thayer

Vinny Thomas

Sarah Tiana

Greta Titelman

Paul F. Tompkins

Shane Torres

Zach Noe Towers

Irene Tu

U

V

Milana Vayntrub

Melissa Villaseñor

W

Trevor Wallace

Matt Walsh

Reggie Watts

Mo Welch

Maggie Winters

X

Monét X Change

Y

Z

Sasheer Zamata

Jenny Zigrino

Zach Zimmerman